Search Result

Pathways Recommended:	Antibody-drug Conjugate/ADC Related

Results for "

conjugates

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Linker (759) Antibody-Drug Conjugates (ADCs) (93) Antibody-Oligonucleotide Conjugates (AOCs) (5) Drug-Linker Conjugates for ADC (352) E3 Ligase Ligand-Linker Conjugates (677) Peptide-Drug Conjugates (PDCs) (14) PROTAC-Linker Conjugates for PAC (9) Radionuclide-Drug Conjugates (RDCs) (83) Target Protein Ligand-Linker Conjugates (60) 17β-HSD (3) ADC Antibody (36) ADC Payload (107) Adrenergic Receptor (1) Akt (9) ALCAM/CD166 (1) Aldehyde Dehydrogenase (ALDH) (1) Amino Acid Derivatives (8) Aminopeptidase (2) AMPK (1) Amyloid-β (5) Anaplastic lymphoma kinase (ALK) (2) Androgen Receptor (6) Angiotensin Receptor (2) ANGPTL (2) Antibiotic (29) Antifolate (3) Apolipoprotein (4) Apoptosis (211) Aurora Kinase (2) AUTACs (5) Autophagy (192) AUTOTACs (6) Bacterial (49) Bcl-2 Family (6) BCL6 (1) Bcr-Abl (12) BCRP (1) Beclin1 (1) Beta-lactamase (1) Biochemical Assay Reagents (357) Btk (6) c-Met/HGFR (6) c-Myc (3) Calcium Channel (1) CaMK (1) Cannabinoid Receptor (1) Carbonic Anhydrase (1) Casein Kinase (2) Caspase (6) CCR (7) CD1 (1) CD19 (1) CD2 (1) CD20 (1) CD22 (6) CD276/B7-H3 (2) CD47 (2) CDK (5) Checkpoint Kinase (Chk) (1) Cholinesterase (ChE) (1) CMV (2) Complement System (3) COX (1) CRM1 (1) CXCR (6) Cytochrome P450 (6) Deubiquitinase (1) DNA Alkylator/Crosslinker (21) DNA/RNA Synthesis (27) Dopamine Receptor (1) Drug Derivative (15) Drug Intermediate (25) Drug Isomer (1) Drug Metabolite (17) E-Selectin (2) E1/E2/E3 Enzyme (5) EGFR (31) Elastase (1) Endogenous Metabolite (101) Endothelin Receptor (1) Ephrin Receptor (2) Epigenetic Reader Domain (29) ERK (2) Estrogen Receptor/ERR (11) Eukaryotic Initiation Factor (eIF) (3) FAAH (2) FAP (5) Fatty Acid Synthase (FASN) (1) Ferroptosis (6) FGFR (3) FKBP (2) FLT3 (3) Fluorescent Dye (106) Folate Receptor (FR) (2) Fungal (1) GABA Receptor (1) Galectin (1) GCGR (2) GHR (3) GLP Receptor (2) Glucocorticoid Receptor (14) GLUT (3) Glutathione Peroxidase (3) Glutathione S-transferase (2) Guanylate Cyclase (1) HBV (3) HCV (2) HDAC (5) Hedgehog (1) Heme Oxygenase (HO) (1) Herbicide (1) HIF/HIF Prolyl-Hydroxylase (4) Histamine Receptor (2) Histone Acetyltransferase (2) Histone Demethylase (1) Histone Methyltransferase (2) HIV (6) HSP (6) HSV (2) IAP (3) IGF-1R (1) IKK (1) Influenza Virus (2) Integrin (12) Interleukin Related (12) IRE1 (1) Isotope-Labeled Compounds (39) JAK (1) JNK (2) Keap1-Nrf2 (1) Kinesin (2) Lactate Dehydrogenase (2) LDLR (1) Leukotriene Receptor (1) Ligands for E3 Ligase (69) Ligands for Target Protein for PROTAC (9) Liposome (63) LXR (1) LYTACs (2) MAGL (1) MAP4K (2) MARCKS (1) MDM-2/p53 (2) Melatonin Receptor (1) Mesothelin (1) MicroRNA (2) Microtubule/Tubulin (108) Mitochondrial Metabolism (4) Mitophagy (2) Mixed Lineage Kinase (2) MMP (3) Molecular Glues (1) Monoamine Oxidase (3) mTOR (1) Mucin (2) N-myristoyltransferase (1) Na+/K+ ATPase (1) NAMPT (4) Nectin-4 (3) Neurokinin Receptor (1) NF-κB (3) Notch (2) Nucleoside Antimetabolite/Analog (5) Opioid Receptor (1) Orexin Receptor (OX Receptor) (1) Orphan GPCR (1) Orthopoxvirus (3) Oxysterol-binding Protein-related Protein (ORP) (1) P2Y Receptor (1) p38 MAPK (1) p62 (1) Parasite (5) PARP (3) PD-1/PD-L1 (10) PERK (1) Phosphodiesterase (PDE) (2) Photosensitizer (1) Phytohormone (2) PI3K (3) PIKfyve (1) PKC (7) Polo-like Kinase (PLK) (1) Potassium Channel (2) PPAR (1) Pregnane X Receptor (PXR) (2) Prolyl Endopeptidase (PREP) (1) Prostaglandin Receptor (1) PROTAC Linkers (209) PROTACs (75) Proteasome (1) Proton Pump (1) PSMA (13) RAR/RXR (1) Ras (4) Reactive Oxygen Species (ROS) (10) Reference Standards (24) RET (2) RIP kinase (2) SARS-CoV (2) Ser/Thr Protease (3) SGK (2) Sigma Receptor (1) Small Interfering RNA (siRNA) (9) SNIPERs (13) SOD (1) Sodium Channel (5) Sodium Phosphate Cotransporter (1) Somatostatin Receptor (11) SOS1 (1) Src (2) STAT (4) STING (12) SWI/SNF Complex (1) TAM Receptor (4) Tau Protein (2) Thrombin (1) Thrombopoietin Receptor (2) Thyroid Hormone Receptor (1) TNF Receptor (12) Toll-like Receptor (TLR) (13) Topoisomerase (87) Transferrin Receptor (4) Transmembrane Glycoprotein (11) Transthyretin (TTR) (2) TROP2 (6) TRP Channel (2) Urease (1) VEGFR (1) Virus Protease (1) WDR5 (2) Wee1 (1) Wnt (1) YAP (2) YTHDF (1) β-catenin (1)
By Research Areas:	Cancer (2491) Cardiovascular Disease (34) Endocrinology (6) Infection (70) Inflammation/Immunology (251) Metabolic Disease (87) Neurological Disease (46)
Click Chemistry:	ADC Synthesis (244) Labeling and Fluorescence Imaging (4) TCO (15) DBCO (77) PROTAC Synthesis (61) Azide (128) BCN (22) Tetrazine (33) Alkynes (70)
Oligonucleotides:	Fluorescent Lipids (7) Pegylated Lipids (48) Nucleotide Analogs (2) Aptamers (1) Phospholipids (3) Cationic Lipids (1) siRNA drugs (9) Polymers (16) Antisense Oligonucleotides (13) Cholesterol (5) siRNAs (11)

3355

Inhibitors & Agonists

Screening Libraries

121

Fluorescent Dye

384

Biochemical Assay Reagents

146

Peptides

MCE Kits

Inhibitory Antibodies

Natural
Products

Isotope-Labeled Compounds

339

Click Chemistry

Oligonucleotides

Targets Recommended: Antibody-Drug Conjugates (ADCs) Peptide-Drug Conjugates (PDCs) Target Protein Ligand-Linker Conjugates PROTAC-Linker Conjugates for PAC Radionuclide-Drug Conjugates (RDCs) Drug-Linker Conjugates for ADC Antibody-Oligonucleotide Conjugates (AOCs) ADC Linker E3 Ligase Ligand-Linker Conjugates

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-175360

*USP7 Ligand-Linker Conjugates* 1**	Target Protein Ligand-Linker Conjugates Deubiquitinase	Cancer
USP7 Ligand-Linker Conjugates 1 is an Target Protein Ligand-Linker Conjugate that incorporates a ligand for USP7 (HY-175359) and a PROTAC linker, which recruits E3 ligases. USP7 Ligand-Linker Conjugates 1 can be used for synthesis of PROTAC USP7 Degrader-1 (HY-175358) .

HY-176788

*EGFR Ligand-Linker Conjugates* 1**	Target Protein Ligand-Linker Conjugates EGFR	Cancer
EGFR Ligand-Linker Conjugates 1 is an Target Protein Ligand-Linker Conjugate that incorporates a ligand for EGFR (HY-150905) and a PROTAC linker, which recruits E3 ligases. EGFR Ligand-Linker Conjugates 1 can be used for synthesis of PROTAC EGFR degrader 3 (HY-144605) .

HY-176791

*CDK12-Cyclin K Ligand-Linker Conjugates* 1**	Target Protein Ligand-Linker Conjugates CDK	Cancer
CDK12-Cyclin K Ligand-Linker Conjugates 1 is an Target Protein Ligand-Linker Conjugate that incorporates a ligand for CDK12-Cyclin K (HY-176790) and a PROTAC linker (HY-W244922), which recruits E3 ligases. CDK12-Cyclin K Ligand-Linker Conjugates 1 can be used for synthesis of PROTAC PP-C8 (HY-144691) .

HY-130270

*AhR Ligand-Linker Conjugates* 1** E3 Ligase Ligand-Linker conjugates 57	E3 Ligase Ligand-Linker Conjugates	Cancer
AhR Ligand-Linker Conjugates 1 (E3 Ligase Ligand-Linker Conjugates 57) incorporates an IAP ligand for the E3 ubiquitin ligase, and a SNIPER linker. AhR Ligand-Linker Conjugates 1 can be used to design SNIPER .

HY-125906

*VHL Ligand-Linker Conjugates* 15** E3 Ligase Ligand-Linker conjugates 56	E3 Ligase Ligand-Linker Conjugates	Cancer
VHL Ligand-Linker Conjugates 15 incorporates an VHL ligand for the E3 ubiquitin ligase, and a PROTAC linker. VHL Ligand-Linker Conjugates 15 can be used to design PROTACs .

HY-139655

*cIAP1 Ligand-Linker Conjugates* 16**	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 16 is an E3 ligase ligand-linker conjugate that can be used in the synthesis of PROTACs.

HY-128820

*cIAP1 Ligand-Linker Conjugates* 1** E3 ligase Ligand-Linker conjugates 41	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 1 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 1 can be used to design SNIPERs .

HY-128819

*cIAP1 Ligand-Linker Conjugates* 3** E3 ligase Ligand-Linker conjugates 40	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 3 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 3 can be used to design SNIPERs .

HY-128822

*cIAP1 Ligand-Linker Conjugates* 13** E3 ligase Ligand-Linker conjugates 43	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 13 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 13 can be used to design SNIPERs .

HY-128813A

*cIAP1 Ligand-Linker Conjugates* 15 hydrochloride** E3 ligase Ligand-Linker conjugates 34 hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 15 hydrochloride incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 15 hydrochloride can be used to design SNIPERs .

HY-128815

*cIAP1 Ligand-Linker Conjugates* 14** E3 ligase Ligand-Linker conjugates 36	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 14 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 14 can be used to design SNIPERs .

HY-128816A

*cIAP1 Ligand-Linker Conjugates* 2 Hydrochloride** E3 ligase Ligand-Linker conjugates 37 Hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 2 Hydrochloride incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 2 Hydrochloride can be used to design SNIPERs .

HY-128826

*cIAP1 Ligand-Linker Conjugates* 10** E3 ligase Ligand-Linker conjugates 47	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 10 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 10 can be used to design SNIPERs .

HY-128812A

*cIAP1 Ligand-Linker Conjugates* 11 Hydrochloride** E3 ligase Ligand-Linker conjugates 33 Hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 11 Hydrochloride incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 11 Hydrochloride can be used to design SNIPERs .

HY-128813

*cIAP1 Ligand-Linker Conjugates* 15** E3 ligase Ligand-Linker conjugates 34	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 15 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 15 can be used to design SNIPERs .

HY-128824

*cIAP1 Ligand-Linker Conjugates* 9** E3 ligase Ligand-Linker conjugates 45	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 9 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 9 can be used to design SNIPERs .

HY-128812

*cIAP1 Ligand-Linker Conjugates* 11** E3 ligase Ligand-Linker conjugates 33	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 11 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 11 can be used to design SNIPERs .

HY-128817

*cIAP1 Ligand-Linker Conjugates* 12** E3 ligase Ligand-Linker conjugates 38	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 12 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 12 can be used to design SNIPERs .

HY-128825

*cIAP1 Ligand-Linker Conjugates* 8** E3 ligase Ligand-Linker conjugates 46	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 8 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 8 can be used to design SNIPERs .

HY-128823

*cIAP1 Ligand-Linker Conjugates* 7** E3 ligase Ligand-Linker conjugates 44	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 7 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 7 can be used to design SNIPERs .

HY-128818

*cIAP1 Ligand-Linker Conjugates* 5** E3 ligase Ligand-Linker conjugates 39	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 5 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 5 can be used to design SNIPERs .

HY-128821

*cIAP1 Ligand-Linker Conjugates* 4** E3 ligase Ligand-Linker conjugates 42	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 4 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 4 can be used to design SNIPERs .

HY-128816

*cIAP1 Ligand-Linker Conjugates* 2** E3 ligase Ligand-Linker conjugates 37	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 2 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 2 can be used to design SNIPERs .

HY-128814

*cIAP1 Ligand-Linker Conjugates* 6 hydrochloride** E3 ligase Ligand-Linker conjugates 35 hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 6 hydrochloride incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 6 hydrochloride can be used to design SNIPERs .

HY-128941

*CCK2R Ligand-Linker Conjugates* 1**	Drug-Linker Conjugates for ADC	Cancer
CCK2R Ligand-Linker Conjugates 1 is a ligand-linker conjugate, which conjugates to the cytotoxic antimicrotubule agents Desacetyl Vinblastine Hydrazide (DAVBH) and Tubulysin B Hydrazide (TubBH) via a hydrophilic peptide linker .

HY-168693

*Target Protein Ligand-Linker Conjugates* 2**	Target Protein Ligand-Linker Conjugates
Target Protein Ligand-Linker Conjugates 2 is a conjugate of the Target Protein Ligand and Linker, consisting of Desmethyl-QCA276 (HY-44103) and the corresponding Linker. Target Protein Ligand-Linker Conjugates 2 can be used to synthesize PROTAC BD-9136 (HY-149878) .

HY-133046

*VHL Ligand-Linker Conjugates* 17**	E3 Ligase Ligand-Linker Conjugates	Cancer
VHL Ligand-Linker Conjugates 17 incorporates a VHL ligand for the E3 ubiquitin ligase, and a PROTAC linker. VHL Ligand-Linker Conjugates 17 can be used in the synthesis of a series of PROTACs, such as ARD-266 (HY-133020). ARD-266 is a highly potent androgen receptor (AR) PROTAC degrader . VHL Ligand-Linker Conjugates 17 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-21930

Pomalidomide-PEG4-C-COOH Cereblon Ligand -Linker conjugates 1; E3 Ligase Ligand-Linker conjugates 1	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide-PEG4-C-COOH (Cereblon Ligand -Linker Conjugate 1) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 4-unit PEG linker used in PROTAC technology.

HY-176787

*KRAS G12C Ligand-Linker Conjugates* 1**	Target Protein Ligand-Linker Conjugates Ras	Cancer
KRAS G12C Ligand-Linker Conjugates 1 is a conjugate of KRAS ^G12C ligand and linker, which can be used in the synthesis of PROTAC YF135 (HY-144323) .

HY-130499

*ERRα Ligand-Linker Conjugates* 1**	Target Protein Ligand-Linker Conjugates	Cancer
ERRα Ligand-Linker Conjugates 1 incorporates a ligand for estrogen-related receptor alpha (ERRα), and a PROTAC linker, which recruit E3 ligases MDM2. ERRα Ligand-Linker Conjugates 1 can be used in the synthesis of a series of PROTACs, such as PROTAC ERRalpha Degrader-1 (HY-128838). PROTAC ERRalpha Degrader-1 is an ERRα degrader .

HY-112618

Thalidomide-O-amido-C6-NH2 Cereblon Ligand-Linker conjugates 11; E3 Ligase Ligand-Linker conjugates 25	E3 Ligase Ligand-Linker Conjugates Autophagy Apoptosis	Cancer
Thalidomide-O-amido-C6-NH2 (Cereblon Ligand-Linker Conjugates 11), a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs .

HY-107439

Thalidomide-O-amido-C8-NH2 Cereblon Ligand-Linker conjugates 2; E3 Ligase Ligand-Linker conjugates 20	E3 Ligase Ligand-Linker Conjugates Autophagy Apoptosis	Cancer
Thalidomide-O-amido-C8-NH2 (Cereblon Ligand-Linker Conjugates 2), a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs .

HY-107438

Thalidomide-O-amido-C4-NH2 Cereblon Ligand-Linker conjugates 6; E3 Ligase Ligand-Linker conjugates 19	E3 Ligase Ligand-Linker Conjugates Autophagy Apoptosis	Cancer
Thalidomide-O-amido-C4-NH2 (Cereblon Ligand-Linker Conjugates 6), a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs .

HY-147225

*TSPO Ligand-Linker Conjugates* 1**	AUTACs Mitophagy	Neurological Disease Metabolic Disease Cancer
TSPO Ligand-Linker Conjugates 1 contains a ligand for translocator protein (TSPO) and a linker, which is used for the synthesis of mitochondria-targeting autophagy-targeting chimera (AUTAC). AUTAC can bind the TSPO on the outer mitochondrial membrane (OMM) of mitochondria and degrades impaired mitochondria and proteins via mitophagy, and improves mitochondrial activity. TSPO Ligand-Linker Conjugates 1 can be used in mitochondrial dysfunction related research, including neurodegenerative diseases, cancer, and diabetes .

HY-128716B

Pomalidomide-PEG3-C2-NH2 hydrochloride Cereblon Ligand-Linker conjugates 5 hydrochloride; E3 ligase Ligand-Linker conjugates 30 hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide-PEG3-C2-NH2 (Cereblon Ligand-Linker Conjugates 5) hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology .

HY-111824

VH032-thiol-C6-NH2 VHL Ligand-Linker conjugates 14; E3 ligase Ligand-Linker conjugates 29	E3 Ligase Ligand-Linker Conjugates	Cancer
VH032-thiol-C6-NH2 (VHL Ligand-Linker Conjugates 14) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used in PROTAC technology.

HY-130521

Pomalidomide-amido-PEG3-C2-NH2 Cereblon Ligand-Linker conjugates 22; E3 ligase Ligand-Linker conjugates 55	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide-amido-PEG3-C2-NH2 (Cereblon Ligand-Linker Conjugates 22) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology .

HY-103614

Thalidomide-O-amido-C8-NH2 TFA 1 Publications Verification Cereblon Ligand -Linker conjugates 2 TFA; E3 Ligase Ligand-Linker conjugates 20 TFA	E3 Ligase Ligand-Linker Conjugates Autophagy Apoptosis	Cancer
Thalidomide-O-amido-C8-NH2 TFA (Cereblon Ligand -Linker Conjugates 2 TFA) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-103613

Thalidomide-O-amido-C4-NH2 TFA Cereblon Ligand-Linker conjugates 6 TFA; E3 ligase Ligand-Linker conjugates 19 TFA	E3 Ligase Ligand-Linker Conjugates Autophagy Apoptosis	Others
Thalidomide-O-amido-C4-NH2 TFA (Cereblon Ligand-Linker Conjugates 6 TFA) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-112618A

Thalidomide-O-amido-C6-NH2 TFA Cereblon Ligand-Linker conjugates 11 TFA; E3 Ligase Ligand-Linker conjugates 25 TFA	E3 Ligase Ligand-Linker Conjugates Autophagy Apoptosis	Cancer
Thalidomide-O-amido-C6-NH2 TFA (Cereblon Ligand-Linker Conjugates 11 TFA), a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs .

HY-128846A

Pomalidomide-C2-NH2 hydrochloride Cereblon Ligand-Linker conjugates 15 hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide-C2-NH2 (Cereblon Ligand-Linker Conjugate 15) hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-107440

Thalidomide-O-amido-PEG3-C2-NH2 Cereblon Ligand-Linker conjugates 3 ; E3 Ligase Ligand-Linker conjugates 14	E3 Ligase Ligand-Linker Conjugates Autophagy Apoptosis	Cancer
Thalidomide-O-amido-PEG3-C2-NH2 (Cereblon Ligand-Linker Conjugates 3) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.

HY-103612

Thalidomide-O-amido-C3-COOH Cereblon Ligand-Linker conjugates 7; E3 ligase Ligand-Linker conjugates 15	E3 Ligase Ligand-Linker Conjugates Autophagy Apoptosis	Cancer
Thalidomide-O-amido-C3-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-115560

Thalidomide-O-amido-C3-NH2 Cereblon Ligand-Linker conjugates 16; E3 Ligase Ligand-Linker conjugates 52	E3 Ligase Ligand-Linker Conjugates Autophagy Apoptosis	Cancer
Thalidomide-O-amido-C3-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-41549

Pomalidomide-PEG4-Ph-NH2 Cereblon Ligand-Linker conjugates 9; E3 Ligase Ligand-Linker conjugates 2	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide-PEG4-Ph-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 4-unit PEG linker used in PROTAC technology.

HY-128716A

Pomalidomide-PEG3-C2-NH2 TFA Cereblon Ligand-Linker conjugates 5 TFA; E3 ligase Ligand-Linker conjugates 30 TFA	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide-PEG3-C2-NH2 TFA (Cereblon Ligand-Linker Conjugates 5 (TFA)) is a synthetic E3 ligase ligand-linker conjugate comprising a Pomalidomide (HY-10984)-based cereblon ligand and a 3-unit PEG linker. Pomalidomide-PEG3-C2-NH2 TFA can be used for the synthesis of PROTACs .

HY-128716

Pomalidomide-PEG3-C2-NH2 Cereblon Ligand-Linker conjugates 5; E3 ligase Ligand-Linker conjugates 30	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide-PEG3-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.

HY-112599

Pomalidomide-PEG4-C2-NH2 Cereblon Ligand-Linker conjugates 8; E3 Ligase Ligand-Linker conjugates 22	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide-PEG4-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 4-unit PEG linker used in PROTAC technology.

HY-125884

Pomalidomide-amido-C4-amido-C6-NH-Boc Cereblon Ligand-Linker conjugates 21; E3 Ligase Ligand-Linker conjugates 54	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide-amido-C4-amido-C6-NH-Boc is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-115560A

Thalidomide-O-amido-C3-NH2 TFA Cereblon Ligand-Linker conjugates 16 TFA; E3 Ligase Ligand-Linker conjugates 52 TFA	E3 Ligase Ligand-Linker Conjugates Autophagy Apoptosis	Cancer
Thalidomide-O-amido-C3-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W007324

Maleimide	Alkaloids Microorganisms Pyrrole Alkaloids Other Alkaloids Source classification Endogenous metabolite Disease Research Fields Cancer	ADC Linker Biochemical Assay Reagents
Maleimide can be used for production of antibody-drug conjugate (ADC) which is used in cancer research. Maleimide also be leveraged for the preparation of fluorogenic probe, which is mainly used for the specific detection of thiol analytes .

HY-141793

ATRA-biotin Biotin-ATRA-conjugate	Alkaloids Classification of Application Fields Other Alkaloids Source classification Endogenous metabolite Disease Research Fields Cancer	RAR/RXR PPAR Endogenous Metabolite Autophagy
ATRA-biotin (Biotin-ATRA-conjugate) is a biotin-conjugated ATRA. ATRA-biotin can be used to track ATRA in cells or a given tissue .

HY-113293A

Estrone sulfate potassium 2 Publications Verification	Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Steroids Cancer	Endogenous Metabolite
Estrone sulfate potassium is a natural endogenous steroid and is an estrogen ester and conjugate .

HY-N1424

Glycoursodeoxycholic acid 3 Publications Verification Ursodeoxycholylglycine	Source classification Endogenous metabolite Steroids	Endogenous Metabolite
Glycoursodeoxycholic acid, a acyl glycine and a bile acid-glycine conjugate, is a metabolite of ursodeoxycholic acid.

HY-124422

Pentacosanoic acid	other families Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Plants Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Pentacosanoic acid is a 25-carbon long-chain saturated fatty acid. Pentacosanoic is a conjugate acid of a pentacosanoate .

HY-N1108

Uvedalin	Terpenoids Smallanthus uvedalia (Linnaeus) Mackenzie Source classification Diterpenoids Plants Compositae	Others
Uvedalin is a conjugated γ-lactone and oxygenated germacranolide that can be isolated from Polymnia uvedalia (L.) .

HY-N16461

Albomycin ε	Microorganisms Antibiotics Source classification	Antibiotic Bacterial
Albomycin ε is a siderophore-antibiotic conjugate targeting bacterial ribosomes (MIC values:>512 μg/mL). Albomycin ε is promising for research of Streptococcus pneumoniae and Staphylococcus aureus infections .

HY-N16460

Albomycin δ2	Microorganisms Antibiotics Source classification	Antibiotic Bacterial
Albomycin δ2 is a siderophore-antibiotic conjugate targeting bacterial ribosomes (MIC: 0.0625 μg/mL against S. pneumoniae, 0.125 μg/mL against MRSA). Albomycin δ2 is promising for research of Streptococcus pneumoniae and Staphylococcus aureus infections .

HY-W741651

Biotin S1P	Lipid	Biochemical Assay Reagents
Biotin S1P is a biotinylated lipid that can be conjugated to streptavidin.

HY-N8252

Xanthoquinodin A1	Infection Quinones Microorganisms Classification of Application Fields Source classification Naphthalene Quinones Disease Research Fields	Antibiotic
Xanthoquinodin A1 is an anticoccidial antibiotic having a new xanthone-anthraquinone conjugate system .

HY-N15827

Glyco-ω-muricholanoic acid	Lipid	Endogenous Metabolite
Glyco-ω-muricholanoic acid is an endogenous metabolite and a glycine conjugated bile acid (BA) of ω-Muricholanoic Acid.

HY-N15970

18:1-12:0 Biotin PA ammonium	Lipid	Biochemical Assay Reagents
18:1-12:0 Biotin PA ammonium is a biotinylated form of phosphatidic acid that can be conjugated to streptavidin.

HY-N1424R

Glycoursodeoxycholic acid (Standard) Ursodeoxycholylglycine (Standard)	Microorganisms Source classification Endogenous metabolite Steroids	Reference Standards Endogenous Metabolite
Glycoursodeoxycholic acid (Standard) is the analytical standard of Glycoursodeoxycholic acid. This product is intended for research and analytical applications. Glycoursodeoxycholic acid, a acyl glycine and a bile acid-glycine conjugate, is a metabolite of ursodeoxycholic acid.

HY-N0324A

Cholic acid sodium 15+ Cited Publications Sodium cholate	Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite
Cholic acid sodium is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. Cholic acid sodium is orally active .

HY-N0324

Cholic acid 15+ Cited Publications	Human Gut Microbiota Metabolites Microorganisms Other disease Classification of Application Fields Source classification Disease markers Metabolic Disease Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite
Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. Cholic acid is orally active .

HY-N0324B

Cholic acid sodium hydrate	Source classification Endogenous metabolite Steroids	Endogenous Metabolite
Cholic acid sodium hydrate is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. Cholic acid sodium hydrate facilitates fat absorption and cholesterol excretion. Cholic acid sodium hydrate is orally active .

HY-W034595

Eicosanedioic acid	Microorganisms Source classification	ADC Linker PROTAC Linkers
Eicosanedioic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Eicosanedioic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis

HY-117371

Hemiasterlin (-)-Hemiasterlin; Milnamide B	Alkaloids Animals Classification of Application Fields Marine natural products Sponge Disease Research Fields Indole Alkaloids Cancer	ADC Payload
Hemiasterlin ((-)-Hemiasterlin) is an antimitotic marine natural product with potent anticancer effects. Hemiasterlin can be used as a cytotoxic payload (ADC Cytotoxin) in antibody-drug conjugates (ADCs) .

HY-N16319

DSG-pSar25	Lipid	Biochemical Assay Reagents
DSG-pSar25 is a lipid conjugated to DSG and pSar25 polymer. DSG-pSar25 can be used to prepare lipid nanoparticles for drug delivery.

HY-N16040

DMG-pSar25	Lipid	Biochemical Assay Reagents
DMG-pSar25 is a lipid conjugated to DMG and pSar25 polymer. DMG-pSar25 can be used to prepare lipid nanoparticles for drug delivery.

HY-N15903

DSPE-PEG2k-tri Mannose ammonium	Lipid	Biochemical Assay Reagents
DSPE-PEG2k-tri Mannose ammonium is a trimannose-DSPE-conjugated PEG derivative that can be used to synthesize lipid nanoparticles for drug delivery.

HY-77641

Cinnamoylglycine	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Cinnamoylglycine is a human urinary metabolite and PPG analog. Cinnamoylglycine is a conjugate of cinnamic acid and glycine. Cinnamoylglycine is used as a urine marker. Cinnamoylglycine can be used in adipogenic differentiation studies .

HY-W041895

DL-Glutamic acid	Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
DL-Glutamic acid is the conjugate acid of Glutamic acid, which acts as a fundamental metabolite. Comparing with the second phase of polymorphs α and β L-Glutamic acid, DL-Glutamic acid presents better stability .

HY-W034918

Docosanedioic acid	other families Classification of Application Fields Ketones, Aldehydes, Acids Source classification Plants Disease Research Fields Cancer	ADC Linker PROTAC Linkers
Docosanedioic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Docosanedioic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

HY-124422R

Pentacosanoic acid (Standard)	other families Ketones, Aldehydes, Acids Source classification Plants Endogenous metabolite	Reference Standards Endogenous Metabolite
Pentacosanoic acid (Standard) is the analytical standard of Pentacosanoic acid. This product is intended for research and analytical applications. Pentacosanoic acid is a 25-carbon long-chain saturated fatty acid. Pentacosanoic is a conjugate acid of a pentacosanoate[1].

HY-N15976

DMG-pSar25 Maleimide	Lipid	Biochemical Assay Reagents
DMG-pSar25 Maleimide is a lipid conjugated to DMG, Maleimide and pSar25 polymer. DMG-pSar25 Maleimide can be used to prepare lipid nanoparticles for drug delivery.

HY-N16041

N-Octadecyl-pSar25	Lipid	Biochemical Assay Reagents
N-Octadecyl-pSar25 is a lipid that is composed of a N-octadecyl unit conjugated to a pSar25 polymer. N-Octadecyl-pSar25 can be used to synthesize lipid nanoparticles for drug delivery.

HY-N16037

N-Dodecyl-pSar25	Lipid	Biochemical Assay Reagents
N-Dodecyl-pSar25 is a lipid that is composed of a N-dodecyl unit conjugated to a pSar25 polymer. N-Dodecyl-pSar25 can be used to synthesize lipid nanoparticles for drug delivery.

HY-131663

L-Lysinamide	Microorganisms Source classification Amino acids	Amino Acid Derivatives
L-Lysinamide is an amide form of L-Lysine (HY-N0469). L-Lysinamide can be conjugated with Cholesterol (HY-N0322) and L-ornithinamide for use as a DNA delivery agent .

HY-N16285

DSPE-PEG400 carboxylic acid sodium	Lipid	Biochemical Assay Reagents
DSPE-PEG400 carboxylic acid sodium is a lipid that consists of a DSPE-PEG400 unit conjugated to a carboxy group. DSPE-PEG400 carboxylic acid sodium can be used to prepare lipid nanoparticles for drug delivery.

HY-116374

Glycolithocholic acid 2 Publications Verification Lithocholylglycine	Human Gut Microbiota Metabolites Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields Steroids	Endogenous Metabolite
Glycolithocholic acid (Lithocholylglycine), an endogenous metabolite, is a glycine-conjugated secondary bile acid. Glycolithocholic acid can be used to diagnose ulcerative colitis (UC), non-alcoholic steatohepatitis (NASH) and primary sclerosing cholangitis (PSC) .

HY-N16291

DSG-pSar25-Maleimide	Lipid	Biochemical Assay Reagents
DSG-pSar25-Maleimide is a lipid that is composed of a DSG unit conjugated to a pSar25 polymer. DSG-pSar25-Maleimide can be used to prepare lipid nanoparticles for drug delivery.

HY-N6740

Beta-Zearalanol	Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Phenols Polyphenols Metabolic Disease Antibacterial Disease Research Disease Research Fields	Apoptosis
Beta-Zearalenol is an mycotoxin produced by Fusarium spp, which causes apoptosis and oxidative stress in mammalian reproductive cells . Beta-Zearalenol is the derivative of zearalenone (ZEA) which can conjugate with glucuronic acid .

HY-N16299

DSPE-PEG12 carboxy sodium	Lipid	Biochemical Assay Reagents
DSPE-PEG12 carboxy sodium is a lipid that consists of a DSPE-PEG12 unit conjugated to a carboxy group. DSPE-PEG12 carboxy sodium can be used to prepare lipid nanoparticles for drug delivery.

HY-121271

Kadsurin	Classification of Application Fields Source classification Lignans Phenylpropanoids Plants Schisandraceae Disease Research Fields Inflammation/Immunology Schisandra chinensis (Turcz.) Baill.	Others
Kadsurin, a natural compound from the stems of Kadsura heteroclita (Schizandraceae), results in significant decreases of CCL₄- induced lipid-peroxidation products, such as thiobarbituric acid reactive substances (TBA-RS), conjugated dienes and fluorescent products in the liver of mice .

HY-N7550

Latrunculin M	Natural Products Marine natural products Source classification Sponge	Fluorescent Dye
Latrunculin M is a highly selective actin-macrolide conjugate that can be isolated from marine products. Latrunculin M can be converted from Latrunculin B, which can effectively induce actin depolymerization and is a good probe for detecting the actin skeleton.

HY-101397R

Allopurinol riboside (Standard)	Alkaloids Source classification Endogenous metabolite Indole Alkaloids	Reference Standards Parasite Drug Metabolite Endogenous Metabolite
Cholic acid (Standard) is the analytical standard of Cholic acid. This product is intended for research and analytical applications. Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. Cholic acid is orally active .

HY-122141

Glycohyocholic acid GHCA	Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite
Glycohyocholic acid (GHCA) is a primary conjugated bile acid formed by the conjugation of Cholic acid (HY-N0324) and Glycine (HY-Y0966). Glycohyocholic acid can be used in the study of hepatitis C-related cirrhosis and diabetes mellitus .

HY-N0324R

Cholic acid (Standard) 10+ Cited Publications	Human Gut Microbiota Metabolites Microorganisms Other disease Classification of Application Fields Source classification Disease markers Metabolic Disease Endogenous metabolite Disease Research Fields Steroids	Reference Standards Endogenous Metabolite
Cholic acid (Standard) is the analytical standard of Cholic acid. This product is intended for research and analytical applications. Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. Cholic acid is orally active .

HY-112942

CMP-Sialic acid CMP-Neu5Ac	Natural Products Human Gut Microbiota Metabolites Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
CMP-Sialic acid (CMP-Neu5Ac) is an allosteric inhibitor of UDP-GlcNAc 2-epimerase. CMP-Sialic acid provides a substrate for Golgi sialyltransferases. CMP-Sialic acid is an important sugar nucleotide for biosynthesis of sialic acid and its conjugates .

HY-113095

γ-CEHC	Monophenols Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Phenols Endogenous metabolite Disease Research Fields	Drug Metabolite Endogenous Metabolite
γ-CEHC is a γ-tocopherol (HY-N7148) metabolite. γ-CEHC is mainly excreted into the urine rather than into the bile. γ-CEHC is present in conjugated form in human urine, mainly as glucuronide .

HY-134544

Calendic acid	Ketones, Aldehydes, Acids Source classification Plants Compositae Millettia usaramensis Taub.	Apoptosis
Calendic acid (8(E),10(E),12(Z)-Octadecatrienoic acid) is a conjugated polyunsaturated fatty acid (PUFA) that can be isolated from C. officinalis seed oil. Calendic acid has anticancer activity .

HY-112942A

CMP-Sialic acid sodium salt 2 Publications Verification CMP-Neu5Ac sodium salt	Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
CMP-Sialic acid (CMP-Neu5Ac) sodium salt is an allosteric inhibitor of UDP-GlcNAc 2-epimerase. CMP-Sialic acid sodium salt provides a substrate for Golgi sialyltransferases. CMP-Sialic acid sodium salt is an important sugar nucleotide for biosynthesis of sialic acid and its conjugates .

HY-N0324AR

Cholic acid sodium (Standard) Sodium cholate (Standard)	Source classification Endogenous metabolite Steroids	Reference Standards Endogenous Metabolite
Cholic acid (sodium) (Standard) is the analytical standard of Cholic acid (sodium). This product is intended for research and analytical applications. Cholic acid sodium is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. Cholic acid sodium is orally active[1][2].

HY-N16233

Chol-PEG2000 fluorescein	Lipid	Fluorescent Dye
Chol-PEG2000 fluorescein is a fluorescent lipid that consists of a cholesterol-PEG2000 unit conjugated to fluorescein. Chol-PEG2000 fluorescein can be used to prepare lipid nanoparticles for drug delivery research (Ex/Em = 480/520 nm).

HY-W751418

N-Nervonoyl taurine (Z)-2-tetracos-15-enamidoethanesulfonic acid	Natural Products Source classification Endogenous metabolite	FAAH
N-Nervonoyl taurine ((Z)-2-tetracos-15-enamidoethanesulfonic acid) is a fatty acid-taurine conjugate derived from nervonic acid. N-Nervonoyl taurine is a substrate of fatty acid amide hydrolase (FAAH) discovered during metabolite profiling .

HY-N7497

Protoescigenin	Triterpenes other families Classification of Application Fields Terpenoids Source classification Other Diseases Plants Disease Research Fields	Others
Protoescigenin is the main aglycone of horse chestnut saponin mixture known as escin. Protoescigenin is selected as substrate for exploratory chemistry towards selective protection, followed by propargyl ether formation and subsequent condensation with azido-monosaccharides, to obtain novel triazole linked conjugates of the triterpene .

HY-77641R

Cinnamoylglycine (Standard)	Microorganisms Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Reference Standards Endogenous Metabolite
Cinnamoylglycine (Standard) is the analytical standard of Cinnamoylglycine. This product is intended for research and analytical applications. Cinnamoylglycine is a glycine conjugate of cinnamic acid and a urinary metabolite in human. Cinnamoylglycine is used as a potential urinary biomarker indicating intact or disrupted colonization resistance during and after antibiotic treatment .

HY-N16234

Chol-PEG1000 fluorescein	Lipid	Fluorescent Dye
Chol-PEG1000 fluorescein is a fluorescent lipid that consists of a cholesterol-PEG1000 unit conjugated to fluorescein. Chol-PEG1000 fluorescein can be used to prepare lipid nanoparticles for drug delivery research (Ex/Em = 480/520 nm).

HY-N16323

DSPE-PEG2K-triGalNAc (II) ammonium	Lipid	Biochemical Assay Reagents
DSPE-PEG2K-triGalNAc (II) ammonium is a functionalized PEG lipid that consists of a DSPE unit conjugated to a triGalNAc. DSPE-PEG2K-triGalNAc (II) ammonium can be used to prepare lipid nanoparticles for drug delivery.

Cat. No.	Product Name	Chemical Structure

HY-15575S

VcMMAE-d8
VcMMAE-d8 is an isotope of VcMMAE (HY-15575). VcMMAE-d8 is a *agent-linker conjugate* for ADC** with potent antitumor activity by using the anti-mitotic agent, monomethyl auristatin E (MMAE, a tubulin inhibitor), linked via the lysosomally cleavable dipeptide, valine-citrulline (vc) .

HY-15583S

Auristatin F-d8
Auristatin F-d₈ is deuterium labeled Auristatin F (HY-15583). Auristatin F is a potent cytotoxin in antibo-conjugated agents and an analogue of MMAF. Auristatin F is a potent microtubule inhibitor and vascular damaging agent (VDA). Auristatin F inhibits cell division by preventing tubulin aggregation.Auristatin F can be used in antibody-drug conjugates (ADC) .

HY-145989S

Aminobenzenesulfonic auristatin E-d8
Aminobenzenesulfonic auristatin E-d₈ is the deuterium labeled Aminobenzenesulfonic auristatin E. Aminobenzenesulfonic auristatin E is a drug-linker conjugate for ADC. Aminobenzenesulfonic auristatin E has potent antitumor activity by using Auristatin E (a cytotoxic tubulin modifier), linked via the ADC linker Aminobenzenesulfonic .

HY-N0324S1

Cholic acid-d5
Cholic acid-d₅ is the deuterium labeled Cholic acid. Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion.

HY-N0324S

Cholic acid-d4 3 Publications Verification
Cholic acid-d₄ is the deuterium labeled Cholic acid. Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion.

HY-N1424S

Glycoursodeoxycholic Acid-d4
Glycoursodeoxycholic acid-d₄ (Ursodeoxycholylglycine-d₄) is the deuterium labeled Glycoursodeoxycholic acid. Glycoursodeoxycholic acid, a acyl glycine and a bile acid-glycine conjugate, is a metabolite of ursodeoxycholic acid .

HY-N0324S2

Cholic acid-13C
Cholic acid- ¹³C is the ¹³C-labeled Cholic acid. Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion.

HY-N1420AS2

Rhamnose-13C-2 monohydrate
Rhamnose- ¹³C-2 (monohydrate) is the ¹³C labeled Rhamnose monohydrate. Rhamnose monohydrate (L-Rhamnose monohydrate) is a monosaccharide found in plants and bacteria. Rhamnose monohydrate-conjugated immunogens is used in immunotherapies. Rhamnose monohydrate

HY-W653947

Glycoursodeoxycholic acid-d5
Glycoursodeoxycholic acid-d₅ (Ursodeoxycholylglycine-d₅) is the deuterium labeled Glycoursodeoxycholic acid (HY-N1424). Glycoursodeoxycholic acid, a acyl glycine and a bile acid-glycine conjugate, is a metabolite of ursodeoxycholic acid.

HY-N1420AS

Rhamnose-13C monohydrate
Rhamnose- ¹³C (monohydrate) is the ¹³C labeled Rhamnose monohydrate. Rhamnose monohydrate (L-Rhamnose monohydrate) is a monosaccharide found in plants and bacteria. Rhamnose monohydrate-conjugated immunogens is used in immunotherapies. Rhamnose monohydrate c

HY-12454S

DM4-d6
DM4-d₆ is deuterium labeled DM4. DM4 is is an antitubulin agent that inhibit cell division. DM4 can be used in the preparation of antibody agent conjugate.

HY-77641S

Cinnamoylglycine-d2
Cinnamoylglycine-d₂ is the deuterium labeled Cinnamoylglycine. Cinnamoylglycine is a glycine conjugate of cinnamic acid and a urinary metabolite in human. Cinnamoylglycine is used as a potential urinary biomarker indicating intact or disrupted colonization resistance during and after antibiotic treatment .

HY-Y1055S

Guanine-13C
Guanine- ¹³C is the ¹³C labeled Guanine . Guanine (2-Aminohypoxanthine) is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds.

HY-W019776

Sudan I-d5
Sudan I-d₅ is a the deuterated Sudan I. Sudan I is a diazo-conjugate red dye and can be used as an additive to products such as oils, solvents or polishes. Sudan I inhibits growth of bacterial strains Clostridium perfringens and L. rhamnosus .

HY-13631DS

Dxd-d5
Dxd-d₅ is a deuterium labeled Dxd. Dxd is a potent DNA topoisomerase I inhibitor, with an IC₅₀ of 0.31 μM, used as a conjugated drug of HER2-targeting ADC (DS-8201a) .

HY-W041895S1

DL-Glutamic acid-d3
DL-Glutamic acid-d₃ is the deuterium labeled DL-Glutamic acid. DL-Glutamic acid is the conjugate acid of Glutamic acid, which acts as a fundamental metabolite. Comparing with the second phase of polymorphs α and β L-Glutamic acid, DL-Glutamic acid presents better stability .

HY-W041895S

DL-Glutamic acid-d5
DL-Glutamic acid-d₅ is the deuterium labeled DL-Glutamic acid. DL-Glutamic acid is the conjugate acid of Glutamic acid, which acts as a fundamental metabolite. Comparing with the second phase of polymorphs α and β L-Glutamic acid, DL-Glutamic acid presents better stability .

HY-116374S

Glycolithocholic acid-d4
Glycolithocholic acid-d₄ is the deuterium labeled Glycolithocholic acid. Glycolithocholic acid, an endogenous metabolite, is a glycine-conjugated secondary bile acid and can be used to diagnose ulcerative colitis (UC), non-alcoholic steatohepatitis (NASH) and primary sclerosing cholangitis (PSC) .

HY-18569S

3-Indoleacetic acid-d5 2 Publications Verification
3-Indoleacetic acid-d₅ is the deuterium labeled 3-Indoleacetic acid (HY-18569). 3-Indoleacetic acid-d₅ can be used as internal standard for assay of IAA releases by alkaline hydrolysis of ester and amide conjugates .

HY-Y1055S3

Guanine-15N5
Guanine- ¹⁵N₅ is ¹⁵N labeled Guanine (HY-Y1055). Guanine (2-Aminohypoxanthine) is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds.

HY-13631ES4

Deruxtecan-d5
Deruxtecan-d₅ is deuterium labeled Deruxtecan (HY-13631E). Deruxtecan is an ADC drug-linker conjugate composed of an DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402.

HY-Y1055S1

Guanine-13C,15N2
Guanine- ¹³C, ¹⁵N₂ is the ¹³C and ¹⁵N labeled Guanine . Guanine (2-Aminohypoxanthine) is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds.

HY-Y1055S4

Guanine-13C5
Guanine- ¹³C₅ is ¹³C-labeled Guanine (HY-Y1055). Guanine (2-Aminohypoxanthine) is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds.

HY-I1129

Fmoc-3VVD-OH-d8
Fmoc-3VVD-OH-d₈ is a deuterium labeled Fmoc-3VVD-OH (HY-78921). Fmoc-3VVD-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-13631ES

Deruxtecan-d4
Deruxtecan-d₄ is deuterium labeled Deruxtecan (HY-13631E). Deruxtecan is an ADC drug-linker conjugate composed of an DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402.

HY-13631ES3

Deruxtecan-d2
Deruxtecan-d₂ is the deuterium labeled Deruxtecan (HY-13631E) . Deruxtecan is an ADC drug-linker conjugate composed of an DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402.

HY-114360AS1

Taurohyodeoxycholic acid-d4 sodium
Taurohyodeoxycholic acid-d4 (sodium) is a deuterated labeled Taurohyodeoxycholic acid (sodium) . Taurohyodeoxycholic acid (THDCA) sodium is the taurine-conjugated form of the secondary bile acid hyodeoxycholic acid. Taurohyodeoxycholic acid can also reduce the activity and expression of myeloperoxidase TNF-α and IL-6, as well as colonic damage in TNBS-induced ulcerative colitis mouse model.

HY-13631ES2

Deruxtecan-d4-1
Deruxtecan-d₄-1 is the deuterium labeled Adenosine Deruxtecan (HY-13631E) . Deruxtecan is an ADC drug-linker conjugate composed of an DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402.

HY-Y1055S2

Guanine-13C5,15N5
Guanine- ¹³C₅, ¹⁵N₅ is ¹³C and ¹⁵N-labeled Guanine (HY-Y1055). Guanine (2-Aminohypoxanthine) is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds.

HY-W750488

Glycolithocholic acid-d5
Glycolithocholic acid-d₅ (Lithocholylglycine-d₅) is the deuterium labeled Glycolithocholic acid (HY-116374). Glycolithocholic acid (Lithocholylglycine), an endogenous metabolite, is a glycine-conjugated secondary bile acid. Glycolithocholic acid can be used to diagnose ulcerative colitis (UC), non-alcoholic steatohepatitis (NASH) and primary sclerosing cholangitis (PSC) .

HY-122141S

Glycohyocholic acid-d4
Glycohyocholic acid-d₄ is the deuterium labeled Glycohyocholic acid (HY-122141). Glycohyocholic acid (GHCA) is a primary conjugated bile acid formed by the conjugation of Cholic acid (HY-N0324) and Glycine (HY-Y0966). Glycohyocholic acid can be used in the study of hepatitis C-related cirrhosis and diabetes mellitus .

HY-N6740S

β-Zearalanol-d4
β-Zearalanol-d₄ is a deuterium labeled Beta-Zearalanol (HY-N6740） . Beta-Zearalenol is an mycotoxin produced by Fusarium spp, which causes apoptosis and oxidative stress in mammalian reproductive cells . Beta-Zearalenol is the derivative of zearalenone (ZEA) which can conjugate with glucuronic acid .

HY-N6740S2

Beta-Zearalanol-d5
Beta-Zearalanol-d₅ is the deuterium labeled Beta-Zearalanol (HY-N6740). Beta-Zearalenol is an mycotoxin produced by Fusarium spp, which causes apoptosis and oxidative stress in mammalian reproductive cells . Beta-Zearalenol is the derivative of Zearalenone (HY-103447) which can conjugate with glucuronic acid .

HY-145397S

(4-NH2)-Exatecan-d5
(4-NH2)-Exatecan-d5 is a deuterated labeled (4-NH2)-Exatecan . (4-NH2)-Exatecan (compound A), a topoisomerase inhibitor, is a derivative of Exatecan. (4-NH2)-Exatecan can be used in the synthesis of antibody-drug conjugates (ADCs) .

HY-W004260S2

Arachidic acid-d3
Arachidic acid-d₃ is the deuterium labeled Arachidic acid (HY-W004260). Arachidic acid (Eicosanoic acid) is a long-chain saturated fatty acid. Arachidic acid can be found in the human organism from the plasma phospholipid, fish, cannabis and other plant oils. Arachidic acid conjugated with Chitosan oligosaccharide (HY-112108) can be used for anti-cancer drug delivery research .

HY-W004260S

Arachidic acid-d2
Arachidic acid-d₂ is the deuterium labeled Arachidic acid (HY-W004260). Arachidic acid (Eicosanoic acid) is a long-chain saturated fatty acid. Arachidic acid can be found in the human organism from the plasma phospholipid, fish, cannabis and other plant oils. Arachidic acid conjugated with Chitosan oligosaccharide (HY-112108) can be used for anti-cancer drug delivery research .

HY-W004260S5

Arachidic acid-d4-1
Arachidic acid-d₄-1 is the deuterium labeled Arachidic acid (HY-W004260). Arachidic acid (Eicosanoic acid) is a long-chain saturated fatty acid. Arachidic acid can be found in the human organism from the plasma phospholipid, fish, cannabis and other plant oils. Arachidic acid conjugated with Chitosan oligosaccharide (HY-112108) can be used for anti-cancer drug delivery research .

HY-W004260S4

Arachidic acid-d4
Arachidic acid-d₄ is the deuterium labeled Arachidic acid (HY-W004260). Arachidic acid (Eicosanoic acid) is a long-chain saturated fatty acid. Arachidic acid can be found in the human organism from the plasma phospholipid, fish, cannabis and other plant oils. Arachidic acid conjugated with Chitosan oligosaccharide (HY-112108) can be used for anti-cancer drug delivery research .

HY-W004260S1

Arachidic acid-d39
Arachidic acid-d₃₉ is the deuterium labeled Arachidic acid (HY-W004260). Arachidic acid (Eicosanoic acid) is a long-chain saturated fatty acid. Arachidic acid can be found in the human organism from the plasma phospholipid, fish, cannabis and other plant oils. Arachidic acid conjugated with Chitosan oligosaccharide (HY-112108) can be used for anti-cancer drug delivery research .

HY-W778114

Guanine-13C2,7-15N

Guanine- ¹³C₂, ¹⁵N is the ¹³C- and ¹⁵N-labeled Guanine (HY-Y1055). Guanine is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds. Guanine has the potential to serve as a large-capacity N pool. Guanine has cytotoxic, antinociceptive and neuroprotective effects .

HY-W777809

Guanine-13C2,15N

HY-117259S

Valiltramiprosate-d6

Valiltramiprosate-d₆ (ALZ-801-d₆) is deuterium labeled Valiltramiprosate. ALZ-801 is a potent and orally available small-molecule β-amyloid (Aβ) anti-oligomer and aggregation inhibitor, valine-conjugated proagent of Tramiprosate with substantially improved PK properties and gastrointestinal tolerability compared with the parent compound . ALZ-801 is an advanced and markedly improved candidate for the treatment of alzheimer’s disease .

HY-113427S

trans-Vaccenic acid-d13

trans-Vaccenic acid-d₁₃ is deuterium labeled trans-Vaccenic acid (HY-113427). trans-Vaccenic acid is a naturally occurring trans fatty acid (TFA). trans-Vaccenic acid inhibits nasopharyngeal carcinoma (NPC) cell growth and induces apoptosis through the inhibition of Bad/Akt phosphorylation. trans-Vaccenic acid is a precursor for the synthesis of saturated fatty acid in the rumen and of conjugated Linoleic acid (CLA) at the tissue level. trans-Vaccenic acid exerts hypolipidemic effects in a rat model of obesity .

HY-114816S

N-butyryl-L-Homoserine lactone-d5

N-butyryl-L-Homoserine lactone-d₅ is the deuterium labeled N-Butanoyl-L-homoserine lactone. N-Butanoyl-L-homoserine lactone (C4-HSL) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Butanoyl-L-homoserine lactone has antibacterial activity and is used in antibacterial biofilm . N-Butanoyl-L-homoserine lactone aptamers blocks qurom sensing and inhibits biofilm formation in Pseudomonas aeruginosa .

HY-161022S1

FL118-C3-O-C-amide-C-NH2-d5 formate
FL118-C3-O-C-amide-C-NH2-d5 formate is a deuterium labeled FL118-C3-O-C-amide-C-NH2 formate. FL118-C3-O-C-amide-C-NH2 formate is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-W588263S1

Indole-3-acetyl glutamate-d4

Indole-3-acetyl glutamate-d₄ (IAGlu-d₄) is deuterium labeled Indole-3-acetyl glutamate. Indole-3-acetyl glutamate (IAGlu) is a derivative of the plant hormone indole-3-acetic acid (IAA). As a conjugated form of IAA, Indole-3-acetyl glutamate involves in the transport, storage, and homeostatic regulation of IAA within the plant. Indole-3-acetyl glutamate can be used for research into the effects of plant hormones on the growth and development of plants .

HY-14532S

Brincidofovir-d6

Brincidofovir-d₆ (CMX001-d₆) is the deuterium labeled Brincidofovir (HY-14532). Brincidofovir (CMX001), the lipid-conjugated prodrug of Cidofovir (HY-17438), is an orally available, long-acting antiviral. Brincidofovir shows activity against a broad spectrum of DNA viruses including cytomegalovirus (CMV), adenovirus (ADV), varicella zoster virus, herpes simplex virus, polyomaviruses, papillomaviruses, poxviruses, and mixed double-stranded DNA virus infections. Brincidofovir, an oral antiviral in late stage development, has proven effective against orthopoxviruses in vitro and in vivo. .

HY-W767865

Cyclic GMP sodium-13C5

Cyclic GMP sodium- ¹³C₅ is the ¹³C-labeled Cyclic GMP sodium (HY-113469A). Cyclic GMP (cGMP) sodium, an important second messenger, is a major intracellular mediator of extracellular signals such as nitric oxide (NO) and natriuretic peptides (NPs). Effects of Cyclic GMP sodium occur through three main groups of cellular targets: cGMP-dependent protein kinases (PKGs), cGMP-gated cation channels, and PDEs. Cyclic GMP can inhibit both platelet adhesion and aggregation. cGAMP (Cyclic-GMP-AMP) (HY-12512), a conjugate of Cyclic GMP and AMP, can induce IRF3 phosphorylation and nuclear translocation, enhancing antiviral immune responses .

HY-W654000

Cyclic GMP-13C,15N2

Cyclic GMP- ¹³C, ¹⁵N₂ is ¹³C and ¹⁵N labeled Cyclic GMP (HY-113469). Cyclic GMP (cGMP), an important second messenger, is a major intracellular mediator of extracellular signals such as nitric oxide (NO) and natriuretic peptides (NPs). Effects of Cyclic GMP occur through three main groups of cellular targets: cGMP-dependent protein kinases (PKGs), cGMP-gated cation channels, and PDEs. Cyclic GMP can inhibit both platelet adhesion and aggregation. cGAMP (Cyclic-GMP-AMP) (HY-12512), a conjugate of Cyclic GMP and AMP, can induce IRF3 phosphorylation and nuclear translocation, enhancing antiviral immune responses .

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks