Gly-7-MAD-MDCPT hydrochloride

Cat. No.: HY-132164A Purity: 98.27%: Data Sheet
COA

SDS
Handling Instructions
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Gly-7-MAD-MDCPT (Compound 4b) hydrochloride is an anticancer agent. Gly-7-MAD-MDCPT hydrochloride is a Camptothecin (HY-16560) compound, which shows cytotoxicity to various cancer cells with IC₅₀ values of 10-1000 nM.

For research use only. We do not sell to patients.

Gly-7-MAD-MDCPT hydrochloride Chemical Structure

Size	Stock	Quantity
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Gly-7-MAD-MDCPT hydrochloride:

Gly-7-MAD-MDCPT Get quote

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Molecular Weight

514.92

Formula

C₂₄H₂₃ClN₄O₇

Appearance

Solid

Color

Light yellow to yellow

SMILES

NCC(NCC1=C2C(C(N3C2)=CC([C@](O)(C(OC4)=O)CC)=C4C3=O)=NC5=CC(OCO6)=C6C=C51)=O.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : 16.67 mg/mL (32.37 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.9420 mL	9.7102 mL	19.4205 mL
5 mM	0.3884 mL	1.9420 mL	3.8841 mL
10 mM	0.1942 mL	0.9710 mL	1.9420 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 98.27%

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Data Sheet (276 KB) SDS (251 KB)

COA (261 KB) HNMR (530 KB) CNMR (105 KB) LCMS (96 KB)

Handling Instructions (2659 KB)

References

[1]. Jeffrey Scott, et al. Preparation of camptothecin peptide conjugates as antitumor agents. WO2019195665. 2019 10-10.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.9420 mL	9.7102 mL	19.4205 mL	48.5512 mL
	5 mM	0.3884 mL	1.9420 mL	3.8841 mL	9.7102 mL
	10 mM	0.1942 mL	0.9710 mL	1.9420 mL	4.8551 mL
	15 mM	0.1295 mL	0.6473 mL	1.2947 mL	3.2367 mL
	20 mM	0.0971 mL	0.4855 mL	0.9710 mL	2.4276 mL
	25 mM	0.0777 mL	0.3884 mL	0.7768 mL	1.9420 mL
	30 mM	0.0647 mL	0.3237 mL	0.6473 mL	1.6184 mL