2. Metabolic Enzyme/Protease Vitamin D Related/Nuclear Receptor Cell Cycle/DNA Damage Autophagy
  3. RAR/RXR PPAR Endogenous Metabolite Autophagy
  4. ATRA-biotin

ATRA-biotin  (Synonyms: Biotin-ATRA-conjugate)

Cat. No.: HY-141793 Purity: 98.43%
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Handling Instructions Technical Support

ATRA-biotin (Biotin-ATRA-conjugate) is a biotin-conjugated ATRA. ATRA-biotin can be used to track ATRA in cells or a given tissue.

For research use only. We do not sell to patients.

ATRA-biotin Chemical Structure

ATRA-biotin Chemical Structure

CAS No. : 2226143-93-5

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Based on 1 publication(s) in Google Scholar

ATRA-biotin Related Antibodies

Top Publications Citing Use of Products

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  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

ATRA-biotin (Biotin-ATRA-conjugate) is a biotin-conjugated ATRA. ATRA-biotin can be used to track ATRA in cells or a given tissue[1].

In Vitro

ATRA-biotin (1-10 μM; 1-72 h) has biocompatibility demonstrated via cell viability assays in cultured N2a-cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

ATRA-biotin Related Antibodies
Molecular Weight

625.90

Formula

C36H55N3O4S
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

CC1(C)C(/C=C/C(C)=C/C=C/C(C)=C/C(OCCCCCCNC(CCCC[C@H]2[C@]3([H])[C@](NC(N3)=O)([H])CS2)=O)=O)=C(C)CCC1
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (159.77 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.5977 mL 7.9885 mL 15.9770 mL
5 mM 0.3195 mL 1.5977 mL 3.1954 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.5977 mL 7.9885 mL 15.9770 mL 39.9425 mL
5 mM 0.3195 mL 1.5977 mL 3.1954 mL 7.9885 mL
10 mM 0.1598 mL 0.7988 mL 1.5977 mL 3.9942 mL
15 mM 0.1065 mL 0.5326 mL 1.0651 mL 2.6628 mL
20 mM 0.0799 mL 0.3994 mL 0.7988 mL 1.9971 mL
25 mM 0.0639 mL 0.3195 mL 0.6391 mL 1.5977 mL
30 mM 0.0533 mL 0.2663 mL 0.5326 mL 1.3314 mL
40 mM 0.0399 mL 0.1997 mL 0.3994 mL 0.9986 mL
50 mM 0.0320 mL 0.1598 mL 0.3195 mL 0.7988 mL
60 mM 0.0266 mL 0.1331 mL 0.2663 mL 0.6657 mL
80 mM 0.0200 mL 0.0999 mL 0.1997 mL 0.4993 mL
100 mM 0.0160 mL 0.0799 mL 0.1598 mL 0.3994 mL
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ATRA-biotin Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ATRA-biotin2226143-93-5Biotin-ATRA-conjugateRAR/RXRPPAREndogenous MetaboliteAutophagyRetinoic acid receptorsRetinoid X receptorsPeroxisome proliferator-activated receptorstrackInhibitorinhibitorinhibit

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