2. Antibody-drug Conjugate/ADC Related Immunology/Inflammation Cytoskeleton Cell Cycle/DNA Damage
  3. Antibody-Drug Conjugates (ADCs) PD-1/PD-L1 Microtubule/Tubulin
  4. PF-08046054

PF-08046054 (SGN-PDL1V) is a PD-L1-directed antibody-drug conjugate (ADC), which is comprised of an anti-PD-L1 antibody conjugated to the vedotin drug-linker, VcMMAE (HY-15575). PF-08046054 is direct cytotoxicity to PD-L1-expressing tumor cells via the intracellular delivery of MMAE. PF-08046054 can be used for the study of solid tumors.

For research use only. We do not sell to patients.

PF-08046054 Chemical Structure

PF-08046054 Chemical Structure

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PF-08046054 Related Antibodies

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Description

PF-08046054 (SGN-PDL1V) is a PD-L1-directed antibody-drug conjugate (ADC), which is comprised of an anti-PD-L1 antibody conjugated to the vedotin drug-linker, VcMMAE (HY-15575). PF-08046054 is direct cytotoxicity to PD-L1-expressing tumor cells via the intracellular delivery of MMAE. PF-08046054 can be used for the study of solid tumors[1].

SMILES

[PF-08046054]
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PF-08046054 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PF-08046054SGN-PDL1VPF08046054PF 08046054Antibody-Drug Conjugates (ADCs)PD-1/PD-L1Microtubule/TubulinAntibody-Drug ConjugatesPD-1/Programmed death-ligand 1PD-L1 ADCVcMMAEsolid tumorsInhibitorinhibitorinhibit

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