2. Antibody-drug Conjugate/ADC Related Apoptosis
  3. Antibody-Drug Conjugates (ADCs) Apoptosis
  4. PF-06688992

PF-06688992 is an antibody-drug conjugate (ADC) targeting the GD3 antigen, which is composed of humanized anti-GD3 huR24 linked to a chemotherapeutic agent. PF-06688992 can induce tumor cell apoptosis. PF-06688992 is promising for research of GD3-overexpressing tumors such as melanoma.

For research use only. We do not sell to patients.

PF-06688992

PF-06688992 Chemical Structure

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PF-06688992 Related Antibodies

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Description

PF-06688992 is an antibody-drug conjugate (ADC) targeting the GD3 antigen, which is composed of humanized anti-GD3 huR24 linked to a chemotherapeutic agent. PF-06688992 can induce tumor cell apoptosis. PF-06688992 is promising for research of GD3-overexpressing tumors such as melanoma[1].

Species Reactivity

Human
IC50 & Target

ganglioside GD3
Gene ID

100049518  [NCBI]

Accession
Target

ganglioside GD3
Application

ELISA, FACS, Functional assay
Conjugated

Unconjugated
Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.
SMILES

N/A
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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PF-06688992 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PF-06688992PF06688992PF 06688992Antibody-Drug Conjugates (ADCs)ApoptosisAntibody-Drug ConjugatesADCGD3melanomaInhibitorinhibitorinhibit

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PF-06688992
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HY-P991668
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