Allocholic acid

Cat. No.: HY-125934: Data Sheet
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Allocholic acid is a typically fetal bile acid found in vertebrates and reappears during liver regeneration and carcinogenesis, besides it is also a conjugate acid of allocholate and an isomer of cholic acid. Allocholic acid is a potent and specific stimulant of the adult olfactory system, it has a role as a marine metabolite, a rat metabolite and a human metabolite.

For research use only. We do not sell to patients.

Allocholic acid Chemical Structure

CAS No. : 2464-18-8

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2 Publications Citing Use of MCE Allocholic acid

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Description

In Vitro

Allocholic acid induces the bai operon and stimulates the conversion of [24-¹⁴C] cholic acid to [24-¹⁴C] allodeoxycholic acid in cultures of C. scindens and C. hylemonae allodeoxycholic acid^[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Allocholic acid is the major acidic biliary metabolite of cholestanol in the rat and in the gerbil^[5].
In the rat allolithocholic acid and allodeoxycholic acid undergo 7a-hydroxylation in the liver to provide allochenodeoxycholic and allocholic acids, respectively^[5].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

408.57

Formula

C₂₄H₄₀O₅

CAS No.

2464-18-8

Appearance

Solid

Color

White to light yellow

SMILES

C[C@H](CCC(O)=O)[C@H]1CC[C@@]2([H])[C@]3([H])[C@H](O)C[C@@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])C[C@H](O)[C@]12C

Structure Classification

Steroids

Initial Source

Animals

Microorganisms

Duck gall

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Purity & Documentation

Purity: 99.76%

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Data Sheet (275 KB) SDS (251 KB)

COA (251 KB)

Handling Instructions (2659 KB)

References

[1]. ThomasBriggs, et al. Allocholic acid, the major component in bile from the river carpsucker, Carpiodes carpio (Rafinesque) (Catostomidae). Comp Biochem Physiol B. 1972 Jul 15;42(3):493-6. [Content Brief]

[2]. Li W, et al. The olfactory system of migratory adult sea lamprey (Petromyzon marinus) is specifically and acutely sensitive to unique bile acids released by conspecific larvae. J Gen Physiol. 1995 May;105(5):569-87. [Content Brief]

[3]. Mendoza ME, et al. Physiological characteristics of allo-cholic acid. J Lipid Res. 2003 Jan;44(1):84-92. [Content Brief]

[4]. Ridlon JM, et al. Isolation and characterization of a bile acid inducible 7alpha-dehydroxylating operon in Clostridium hylemonae TN271. Anaerobe. 2010 Apr;16(2):137-46. [Content Brief]

[5]. Elliott WH, Hyde PM. Metabolic pathways of bile acid synthesis. Am J Med. 1971 Nov;51(5):568-79. [Content Brief]

Allocholic acid Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Allocholic acid2464-18-8Endogenous Metabolitevertebratesstimulantolfactorysystemfetalbilemetaboliteolfactory systemisomerInhibitorinhibitorinhibit

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