2. Antibody-drug Conjugate/ADC Related
  3. Drug-Linker Conjugates for ADC
  4. (1R)-Deruxtecan

(1R)-Deruxtecan is a drug-linker conjugates for ADC.

For research use only. We do not sell to patients.

(1R)-Deruxtecan Chemical Structure

(1R)-Deruxtecan Chemical Structure

CAS No. : 2270986-87-1

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Other Forms of (1R)-Deruxtecan:

(1R)-Deruxtecan Related Antibodies

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Description

(1R)-Deruxtecan is a drug-linker conjugates for ADC[1].

Molecular Weight

1034.05

Formula

C52H56FN9O13
CAS No.
Appearance

Solid

Color

Light yellow to brown

SMILES

CC[C@]1(C(OCC2=C1C=C3C4=C(C5=C6C(C=C(C(C)=C6CC[C@H]5NC(COCNC(CNC([C@@H](NC(CNC(CNC(CCCCCN7C(C=CC7=O)=O)=O)=O)=O)CC8=CC=CC=C8)=O)=O)=O)F)=N4)CN3C2=O)=O)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (96.71 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.9671 mL 4.8354 mL 9.6707 mL
5 mM 0.1934 mL 0.9671 mL 1.9341 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.9671 mL 4.8354 mL 9.6707 mL 24.1768 mL
5 mM 0.1934 mL 0.9671 mL 1.9341 mL 4.8354 mL
10 mM 0.0967 mL 0.4835 mL 0.9671 mL 2.4177 mL
15 mM 0.0645 mL 0.3224 mL 0.6447 mL 1.6118 mL
20 mM 0.0484 mL 0.2418 mL 0.4835 mL 1.2088 mL
25 mM 0.0387 mL 0.1934 mL 0.3868 mL 0.9671 mL
30 mM 0.0322 mL 0.1612 mL 0.3224 mL 0.8059 mL
40 mM 0.0242 mL 0.1209 mL 0.2418 mL 0.6044 mL
50 mM 0.0193 mL 0.0967 mL 0.1934 mL 0.4835 mL
60 mM 0.0161 mL 0.0806 mL 0.1612 mL 0.4029 mL
80 mM 0.0121 mL 0.0604 mL 0.1209 mL 0.3022 mL
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(1R)-Deruxtecan Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(1R)-Deruxtecan2270986-87-1Drug-Linker Conjugates for ADCdrug-linker conjugates for ADCInhibitorinhibitorinhibit

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