1. PROTAC
  2. Ligands for Target Protein for PROTAC
  3. TH10184

TH10184 is a NUDT5 inhibitor. TH10184 can be conjugated with VH032 (HY-125845) and linker (HY-W001958) to synthesize PROTAC NUDT5 degrader DDD2 (HY-176261).

For research use only. We do not sell to patients.

TH10184 Chemical Structure

TH10184 Chemical Structure

CAS No. : 2271044-59-6

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Description

TH10184 is a NUDT5 inhibitor. TH10184 can be conjugated with VH032 (HY-125845) and linker (HY-W001958) to synthesize PROTAC NUDT5 degrader DDD2 (HY-176261)[1].

Molecular Weight

466.49

Formula

C22H26N8O4

CAS No.
SMILES

COC(C=C1C(O2)=NN=C2CN3C(C(N(C(N4C)=O)C)=O)=C4N=C3N5CCNCC5)=C(C=C1)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
TH10184
Cat. No.:
HY-176262
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