Fmoc-Gly-Gly-allyl propionate

Cat. No.: HY-400191A: FAQs
Data Sheet Handling Instructions Technical Support

Fmoc-Gly-Gly-allyl propionate is a cleavable linker that can be used to synthesize Antibody-Drug Conjugates (ADCs).

For research use only. We do not sell to patients.

Fmoc-Gly-Gly-allyl propionate Chemical Structure

Size	Price	Stock
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution		Ask For Quote & Lead Time
Solution
10 mM * 1 mL in DMSO		Ask For Quote & Lead Time
Solid
5 mg		Ask For Quote & Lead Time
10 mg		Ask For Quote & Lead Time
25 mg		Ask For Quote & Lead Time
50 mg		Ask For Quote & Lead Time
100 mg		Ask For Quote & Lead Time

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This product is a controlled substance and not for sale in your territory.

Other Forms of Fmoc-Gly-Gly-allyl propionate:

Fmoc-Gly-(d-Gly)-allyl propionate Get quote

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•Related Small Molecules:

•Related Proteins:

View All ADC Linker Isoform Specific Products:

View All Isoforms

Cleavable Linker Non-cleavable Linker Acid Cleavable Linker Disulfide Cleavable Linker Protease Cleavable Linker Glycosidase Cleavable Linker Phosphatase Cleavable Linker

Biological Activity
Purity & Documentation
References
Customer Review

Description

Fmoc-Gly-Gly-allyl propionate is a cleavable linker that can be used to synthesize Antibody-Drug Conjugates (ADCs)^[1].

Molecular Weight

466.48

Formula

C₂₅H₂₆N₂O₇

CAS No.

2766214-15-5

Appearance

Solid

SMILES

C=CCOC(CC[C@@H](C(O)=O)NC(CNC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility

In Vitro:

DMSO : 110 mg/mL (235.81 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.1437 mL	10.7186 mL	21.4371 mL
5 mM	0.4287 mL	2.1437 mL	4.2874 mL
10 mM	0.2144 mL	1.0719 mL	2.1437 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. https://pubchem.ncbi.nlm.nih.gov

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.1437 mL	10.7186 mL	21.4371 mL	53.5929 mL
	5 mM	0.4287 mL	2.1437 mL	4.2874 mL	10.7186 mL
	10 mM	0.2144 mL	1.0719 mL	2.1437 mL	5.3593 mL
	15 mM	0.1429 mL	0.7146 mL	1.4291 mL	3.5729 mL
	20 mM	0.1072 mL	0.5359 mL	1.0719 mL	2.6796 mL
	25 mM	0.0857 mL	0.4287 mL	0.8575 mL	2.1437 mL
	30 mM	0.0715 mL	0.3573 mL	0.7146 mL	1.7864 mL
	40 mM	0.0536 mL	0.2680 mL	0.5359 mL	1.3398 mL
	50 mM	0.0429 mL	0.2144 mL	0.4287 mL	1.0719 mL
	60 mM	0.0357 mL	0.1786 mL	0.3573 mL	0.8932 mL
	80 mM	0.0268 mL	0.1340 mL	0.2680 mL	0.6699 mL
	100 mM	0.0214 mL	0.1072 mL	0.2144 mL	0.5359 mL