1. Antibody-drug Conjugate/ADC Related GPCR/G Protein Cytoskeleton Cell Cycle/DNA Damage Apoptosis
  2. Antibody-Drug Conjugates (ADCs) Endothelin Receptor Microtubule/Tubulin Apoptosis
  3. DEDN6526A

DEDN6526A is an antibody-drug conjugate (ADC) consisting of the humanized anti-ETBR antibody DEDN6526A (RG-7636) (HY-P990573 conjugated with valine-citrulline (vc) and the tubulin inhibitor MMAE (McMMAF) (HY-15575). DEDN6526A induces apoptosis and can be used in melanoma research.

For research use only. We do not sell to patients.

DEDN6526A Chemical Structure

DEDN6526A Chemical Structure

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Description

DEDN6526A is an antibody-drug conjugate (ADC) consisting of the humanized anti-ETBR antibody DEDN6526A (RG-7636) (HY-P990573 conjugated with valine-citrulline (vc) and the tubulin inhibitor MMAE (McMMAF) (HY-15575). DEDN6526A induces apoptosis and can be used in melanoma research[1].

SMILES

[DEDN6526A]

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
DEDN6526A
Cat. No.:
HY-171734
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