2. Antibody-drug Conjugate/ADC Related Protein Tyrosine Kinase/RTK JAK/STAT Signaling Immunology/Inflammation
  3. Antibody-Drug Conjugates (ADCs) EGFR Toll-like Receptor (TLR)
  4. Pertuzumab zuvotolimod

Pertuzumab zuvotolimod  (Synonyms: SBT6050)

Cat. No.: HY-P9994
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Pertuzumab zuvotolimod (SBT6050) is an anti-HER2 antibody-drug conjugate (ADC). Pertuzumab zuvotolimod is composed of a humanized anti-HER2 antibody (Pertuzumab) (HY-P9912A), a linker, a TLR8 agonist payload, and the drug-linker conjugate for ADC is Zuvotolimod (HY-145620). Pertuzumab zuvotolimod potently induces multiple anti-tumor immune activities through the direct activation myeloid cells and the subsequent induction of T and NK cell cytolytic activity. Pertuzumab zuvotolimod can be used for HER2-expressing solid tumors research.

For research use only. We do not sell to patients.

CAS No. : 2500674-05-3

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Pertuzumab zuvotolimod Related Antibodies

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Description

Pertuzumab zuvotolimod (SBT6050) is an anti-HER2 antibody-drug conjugate (ADC). Pertuzumab zuvotolimod is composed of a humanized anti-HER2 antibody (Pertuzumab) (HY-P9912A), a linker, a TLR8 agonist payload, and the drug-linker conjugate for ADC is Zuvotolimod (HY-145620). Pertuzumab zuvotolimod potently induces multiple anti-tumor immune activities through the direct activation myeloid cells and the subsequent induction of T and NK cell cytolytic activity. Pertuzumab zuvotolimod can be used for HER2-expressing solid tumors research[1].

IC50 & Target

ERBB2/HER2/CD340
CAS No.
SMILES

[Pertuzumab zuvotolimod]
Storage

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Format
  • Human IgG1 kappa
Purity & Documentation
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Pertuzumab zuvotolimod Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pertuzumab zuvotolimod2500674-05-3SBT6050SBT 6050SBT-6050Antibody-Drug Conjugates (ADCs)EGFRToll-like Receptor (TLR)Antibody-Drug ConjugatesEpidermal growth factor receptorErbB-1HER1HER2Antibody-drug conjugateADCAnti-tumorImmuneSolid tumorsInhibitorinhibitorinhibit

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