2. PROTAC Apoptosis
  3. Ligands for Target Protein for PROTAC Bcl-2 Family
  4. BCL-xL ligand 2

BCL-xL ligand 2 is a ligand for BCL-xL. BCL-xL ligand 2 can be conjugated with E3 ligase Ligand (HY-138793) and linker to synthesize Bcl-xL PROTAC degrader PZ671 (HY-174876).

For research use only. We do not sell to patients.

BCL-xL ligand 2 Chemical Structure

BCL-xL ligand 2 Chemical Structure

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BCL-xL ligand 2 Related Antibodies

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Bcl-2 Bcl-xL Bcl-W Mcl-1 Bfl-1 Bcl-B Bax Bak Bim

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Description

BCL-xL ligand 2 is a ligand for BCL-xL. BCL-xL ligand 2 can be conjugated with E3 ligase Ligand (HY-138793) and linker to synthesize Bcl-xL PROTAC degrader PZ671 (HY-174876)[1].

Molecular Weight

903.49

Formula

C43H46ClF3N4O6S3
SMILES

O=C(NS(=O)(C1=CC=C(N[C@@H](CSC2=CC=CC=C2)CC=O)C(S(=O)(C(F)(F)F)=O)=C1)=O)C3=CC=C(N4CCN(CC5=C(C6=CC=C(Cl)C=C6)CCC(C)(C)C5)CC4)C=C3
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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BCL-xL ligand 2 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BCL-xL ligand 2Ligands for Target Protein for PROTACBcl-2 FamilyTarget Protein-binding MoietyInhibitorinhibitorinhibit

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