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2336

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

MCE Kits

Inhibitory Antibodies

315

Natural
Products

319

Recombinant Proteins

Isotope-Labeled Compounds

141

Antibodies

Click Chemistry

790

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-106031

F-14512	Topoisomerase	Cancer
F-14512 is a targeted cytotoxic compound that utilizes the polyamine transport system (PTS) to selectively deliver polyamine-containing drugs to cancer cells. F-14512 combines an epipodophyllotoxin core that targets topoisomerase II with a spermine group that acts as a cell delivery vehicle, with improved selectivity for tumor cells. F-14512 exhibits significant cytotoxicity against cells with high PTS activity and demonstrates high potency in multiple human cell lines (median IC₅₀=0.18 μM). In the MX1 breast tumor xenograft model, F-14512 exhibits potent antitumor activity .

HY-19886

F 16915	Drug Intermediate	Cardiovascular Disease
F 16915, a Docosahexaenoic Acid (DHA, HY-B2167) derivative, is a potent pro-agent of DHA. F 16915 can prevent heart failure-induced atrial fibrillation .

HY-146232

F 13714 F 14679	5-HT Receptor	Others
F 13714 (F 14679) is a prototypical 5-HT_1A agonist with a pK_i of 10.23. F 13714 induces large Ca ²⁺ responses .

HY-115969

F-17	Bacterial	Infection
F-17 is a potential inhibitor of virulence factor. F-17 shows very significant inhibitory effect on biofilm, elastase, pyocyanin, and swarming motility. F-17 also shows a good binding effect on LasR and PqsR. F-17 has no obvious cytotoxicity .

HY-106902

F-1394	Acyltransferase	Cardiovascular Disease
F-1394 is an orally active acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor that inhibits dietary cholesterol absorption in mice. F-1394 can be used in cardiovascular disease research .

HY-N6217

F-14329	Endogenous Metabolite	Others
F-14329 is a tetramic acid fungal metabolite .

HY-N10471

F3226-1387	Parasite Endogenous Metabolite	Infection
F3226-1387 is a potent Entamoeba histolytica O-acetylserine sulfhydrylase EhOASS3 inhibitor with an IC₅₀ value of 38 μM. F3226-1387 can suppress the growth of the amoeba .

HY-161758

F0045(S)	Influenza Virus	Infection
F0045(S) is a potent influenza hemagglutinin inhibitor with a K_D value of 6.1 µM. F0045(S) protects human cells from influenza infection .

HY-172958

F6524-1593	Anaplastic lymphoma kinase (ALK)	Cancer
F6524-1593 is an ALK inhibitor. F6524-1593 has inhibitory activity against A549 and HepG-2 cells with IC₅₀ values of 161.1 μM and 91.03 μM, respectively. F6524-1593 can be used in the research of ALK-related cancers (such as non-small cell lung cancer, lymphoma and neuroblastoma) .

HY-N11430

F1839-I	HIV	Infection
F1839-I is a compound that can be isolated from Stachybotrys. F1839-I has weak cytotoxicity and anti-HIV activity with an IC₅₀ value of 15.6 μM .

HY-171148

F1-RIBOTAC	PROTACs	Cancer
F1-RIBOTAC is a ribonuclease-targeting chimeras (RIBOTACs). F1-RIBOTAC decreases QSOX1-a mRNA expression level in an RNase L-dependent manner. F1-RIBOTAC can be used for the research of cancer . (Pink: RNA ligand (HY-168460); Black: linker (HY-W008005); Blue: RNase L ligand (HY-168452))

HY-154850

F-CRI1	STING	Cancer
F-CRI1 is a potent STING agonist with a K_d value of 40.62 nM. F-CRI1 is a radioactive probe with 18F-labeled modification. F-CRI1 can be used to study STING visualization in the tumor microenvironment .

HY-W590849

F1874-108	Endogenous Metabolite	Metabolic Disease
F1874-108 is an inhibitor of brassinosteroid biosynthesis and signal transduction .

HY-163436

F44-A13	FXR Cytochrome P450 RAR/RXR PPAR ROR	Metabolic Disease
F44-A13 is an orally active and highly selective farnesoid X receptor (FXR) antagonist with an IC₅₀ value of 1.1 μM. F44-A13 can optimize cholesterol metabolism and reduce its activity by inducing CYP7A1 expression. F44-A13 reduces levels of cholesterol, triglycerides, and low-density lipoprotein cholesterol (LDL-C) in mouse models. F44-A13 can be used in the study of metabolic diseases associated with lipid disorders .

HY-123363

Tafluposide F-11782	Topoisomerase	Cancer
Tafluposide (F-11782) is a DNA topoisomerase inhibitor. Tafluposide has antitumor activity .

HY-P10310

F9170	HIV	Infection
F9170 is an amphipathic peptide with an activity of inactivate HIV-1 virions. F9170 targets the conserved cytoplasmic tail of HIV-1 env and disrupts the integrity of the viral membrane. F9170 is able to cross the blood-brain barrier (BBB) .

HY-19463A

F15845	Sodium Channel	Cardiovascular Disease
F 15845 is a highly effective persistent sodium current blocker. F 15845 also is a cardioprotective agent, has anti-ischemic activity and exerts short- and long-term cardioprotection after myocardial infarction. F 15845 can be used for the research of myocardium functional impairment .

HY-137985

Mer-NF5003F Stachybotrydial; F 1839M; Stachybotrydial	HSV Virus Protease	Infection
Mer-NF5003F (Stachybotrydial; F 1839M), a sesquiterpene isolated from Stachybotrys, inhibits avian medulloblastoma virus (AMV) protease (IC₅₀=7.8 μM). Mer-NF5003F inhibits sialyltransferase 6N (ST6N), ST3O, and ST3N (IC₅₀=0.61, 6.7, and 10 μg/mL, respectively), and fucosyltransferase (IC₅₀=11.3 μg/mL). Mer-NF5003F has in vitro activity against herpes simplex virus HSV-1 (IC₅₀=4.32 μg/mL) and multidrug-resistant Plasmodium falciparum K1 strain (IC₅₀=0.85 μg/mL).

HY-158231

Polyether F127 Diacrylate F127DA	Biochemical Assay Reagents	Others
Polyether F127 Diacrylate (F127DA) is a triblock copolymer of acrylated polyethylene glycol-polypropylene glycol-polyethylene glycol. Polyether F127 Diacrylate rapidly crosslinks and cures to form a gel under the action of photoinitiators in UV and visible light. Polyether F127 Diacrylate has excellent thermo-gelling properties and good biosafety. Polyether F127 Diacrylate needs to self-assemble into fibrous hydrogel under the action of photoinitiator LAP (HY-44076), and target bioactive adhesion sites, play an inherent supporting role for tissue cells and biodegradable activity. Application: cell culture, biological 3D printing, tissue engineering, etc.

HY-101510

F1063-0967	Phosphatase	Cancer
F1063-0967 is a Dual-specificity phosphatase 26 (DUSP26) inhibitor with an IC₅₀ of 11.62 μM.

HY-D1779

Fura-5F pentapotassium	Fluorescent Dye	Others
Fura-5F pentapotassium is a cell-impermeant fluorescent calcium indicator.

HY-163281

FSY-OSO2F	Fluorescent Dye	Cancer
FSY-OSO2F shows an uptake in MCF-7 cells through the regulation of L-Tyr, ASC, and ASC2 transporters. FSY-OSO2F can be used as a PET tracer, when labeled with ¹⁸F, and exhibits good uptake and good contrast in MCF-7 and 22Rv1 subcutaneous tumors .

HY-139171

F092	PGE synthase	Inflammation/Immunology
F092 is an inhibitor of hematopoietic prostaglandin D synthase (H-PGDS) with a K_D value of 0.14 nM. F092 can be used in the study of allergic and inflammatory responses .

HY-126560

F-Amidine	Protein Arginine Deiminase	Inflammation/Immunology
F-Amidine is a Protein arginine deiminase 4 (PAD4) inhibitor. F-Amidine can be used in the study of inflammatory and immune system diseases (such as rheumatoid arthritis) .

HY-D1761

Fura-4F pentapotassium	Fluorescent Dye	Others
Fura-4F pentapotassium is a cell-impermeant fluorescent indicator for intracellular calcium ion measurement.

HY-P10310A

F9170 TFA	HIV	Infection
F9170 TFA is an amphipathic peptide with an activity of inactivate HIV-1 virions. F9170 TFA targets the conserved cytoplasmic tail of HIV-1 env and disrupts the integrity of the viral membrane. F9170 TFA is able to cross the blood-brain barrier (BBB) .

HY-D1492

Fast Sulphon Black F	Fluorescent Dye	Others
Fast Sulphon Black F is a specific copper indicator. Fast Sulphon Black F can be used for EDTA titration .

HY-150190

F5446	Histone Methyltransferase Apoptosis	Cancer
F5446 (Compound 1) is a selective small molecule inhibitor of SUV39H1 methyltransferase. F5446 decreases H3K9me3 deposition at the FAS promoter, increases Fas expression and increases colorectal carcinoma cell sensitivity to FasL-induced apoptosis in vitro. F5446 suppresses human colon tumor xenograft growth in vivo .

HY-19863A

F-15599 tosylate NLX-101 tosylate	5-HT Receptor	Neurological Disease
F-15599 tosylate is a highly selective G-protein biased 5-HT1A receptor agonist, with K_i of 3.4 nM.

HY-19863

F-15599 2 Publications Verification NLX-101	5-HT Receptor	Neurological Disease
F-15599 is a highly selective G-protein biased 5-HT1A receptor agonist, with K_i of 3.4 nM.

HY-126560A

F-Amidine TFA	Protein Arginine Deiminase	Inflammation/Immunology
F-Amidine TFA is a Protein arginine deiminase 4 (PAD4) inhibitor. F-Amidine TFA can be used in the study of inflammatory and immune system diseases (such as rheumatoid arthritis) .

HY-160943A

F594-1001 hydrochloride	SARS-CoV	Infection
F594-1001 (compound 6) hydrochloride is a potent and highly selective SARS-CoV-2 Mac1-ADP-ribose inhibitor with IC₅₀s of 8.5 μM, 68 μM and 45 μM for SARS-CoV-2 in AS, FP, and FRET assays, respectively. F594-1001 hydrochloride directly binds to SARS-CoV-2 Mac1 and exhibits a dose-dependent inhibition of Mac1 ADP-ribosylhydrolase activity .

HY-160943

F594-1001	SARS-CoV	Infection
F594-1001 (compound 6) is a potent and highly selective SARS-CoV-2 Mac1-ADP-ribose inhibitor with IC₅₀s of 8.5 μM, 68 μM and 45 μM for SARS-CoV-2 in AS, FP, and FRET assays, respectively. F594-1001 directly binds to SARS-CoV-2 Mac1 and exhibits a dose-dependent inhibition of Mac1 ADP-ribosylhydrolase activity .

HY-147845

F8-S40	SARS-CoV	Infection
F8-S40 is an inhibitor of SARS-CoV-2 main protease, with an IC₅₀ of 10.88 μM .

HY-128901

F 13714 fumarate F 14679 fumarate	5-HT Receptor	Neurological Disease
F13714 fumarate, a selective 5-HT1A receptor biased agonist, shows antidepressant-like properties after a single administration in the mouse model of chronic mild stress .

HY-101427

Bamaquimast F 10126; L 0042	Others	Inflammation/Immunology
Bamaquimast (F 10126; L 0042) is a potent antiasthmatic agent .

HY-159045

F-SAHA p-Fluoro-SAHA	HDAC	Cancer
F-SAHA is a HDAC inhibitor (HDACi) and its ¹⁸F labeled derivative can be used in tumor imaging research .

HY-N14340

Fibrostatin F	HIF/HIF Prolyl-Hydroxylase	Metabolic Disease
Fibrostatin F is a proline hydroxylase inhibitor found in Strptomyces catenulae .

HY-P0041

F992	Vasopressin Receptor	Neurological Disease
F992 is an antidiuretic peptide and vasopressin (antidiuretic hormone) analogue .

HY-D1758

Fura-5F AM	Fluorescent Dye	Others
Fura-5F AM is a membrane-permeant fluorescent calcium indicator. Upon entering the cell, this probe is hydrolyzed by cytosilic esterases and trapped as the active chelator.

HY-D1759

Fura-4F AM	Fluorescent Dye	Others
Fura-4F AM is a cell-permeant fluorescent calcium indicator. Upon entering the cell, this probe is hydrolyzed by cytosilic esterases and trapped as the active chelator.

HY-153990

FKBP51F67V-selective antagonist Ligand2	FKBP	Neurological Disease
FKBP51F67V-selective antagonist Ligand2 (example 3-3) is a potent FKBP51 F67V-selective antagonist ligand. FKBP51F67V-selective antagonist Ligand2 reverses the anxiogenic phenotype induced by overexpression of FKBP51 F67V in the amygdala. FKBP51F67V-selective antagonist Ligand2 binds to FKBP51 F67V, but not to wild-type FKBP51 or FKBP52 .

HY-19286

Eflucimibe F 12511	Acyltransferase	Cancer
Eflucimibe (F 12511) is a new acyl-coenzyme A cholesterol O-acyltransferase (ACAT) inhibitor. Eflucimibe can be used in the research of atherosclerosis .

HY-104029

Olorofim F901318	Fungal Dihydroorotate Dehydrogenase	Infection
Olorofim (F901318) selectively inhibits fungal dihydroorotate dehydrogenase (DHODH), a key enzyme in the pyrimidine biosynthesis pathway. Olorofim (F901318). Olorofim exhibits excellent activity against A. fumigatus and other Aspergillus spp. .

HY-103091

Donitriptan hydrochloride F-11356	5-HT Receptor	Neurological Disease
Donitriptan hydrochloride (F-11356) is a potent, high efficacy agonist at 5-HT_1B/1D receptors with pK_is of 9.4 and 9.3, respectively .

HY-W391641

F8BT	Biochemical Assay Reagents Endogenous Metabolite
F8BT is a polymer material with excellent photoelectric properties. F8BT is widely used in organic light-emitting diodes (OLEDs) and organic solar cells (PLEDs), and can effectively improve the luminous efficiency and energy conversion efficiency of the devices. The structure of F8BT makes it perform well in photoelectric conversion and electron transport, making it an important object of modern electronic material research.

HY-100866B

F1324 acetate	Bcl-2 Family	Cancer
F1324 acetate is a potent, high affinity peptidic inhibitor of B cell lymphoma 6 (BCL6), with an IC₅₀ of 1 nM. F1324 acetate exhibits binding t_1/2 value of 441 s and has strong inhibition activity against BCL6 PPI .

HY-100866

F1324	Bcl-2 Family	Cancer
F1324 is a potent, high affinity peptidic inhibitor of B cell lymphoma 6 (BCL6) with an IC₅₀ of 1 nM. F1324 exhibits binding t_1/2 value of 441 s and has strong inhibition activity against BCL6 PPI .

HY-158465

GPEP FA2-KVANKT glycopeptide F(3)A2 glycan-KVANKT & F(6)A2 glycan-KVANKT	Biochemical Assay Reagents	Others
GPEP FA2-KVANKT glycopeptide (F(3)A2 glycan-KVANKT & F(6)A2 glycan-KVANKT) is a N-polysaccharide protein and a multifunctional fluorescent linker. The resulting conjugates exhibit high sensitivity and specificity by mimicking the antennal elements of N-glycans .

HY-RS04646

F8 Human Pre-designed siRNA Set A AHF; F8B; F8C; HEMA; FVIII; THPH13; DXS1253E	Small Interfering RNA (siRNA)	Others
F8 Human Pre-designed siRNA Set A contains three designed siRNAs for F8 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

F8 Human Pre-designed siRNA Set A F8 Human Pre-designed siRNA Set A

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N6217

F-14329	Alkaloids Monophenols Microorganisms Pyrrole Alkaloids Classification of Application Fields Source classification Other Diseases Phenols Disease Research Fields	Endogenous Metabolite
F-14329 is a tetramic acid fungal metabolite .

HY-N10471

F3226-1387	Natural Products Microorganisms Source classification	Parasite Endogenous Metabolite
F3226-1387 is a potent Entamoeba histolytica O-acetylserine sulfhydrylase EhOASS3 inhibitor with an IC₅₀ value of 38 μM. F3226-1387 can suppress the growth of the amoeba .

HY-N11430

F1839-I	Structural Classification Monophenols Microorganisms Source classification Phenols	HIV
F1839-I is a compound that can be isolated from Stachybotrys. F1839-I has weak cytotoxicity and anti-HIV activity with an IC₅₀ value of 15.6 μM .

HY-N14340

Fibrostatin F	Quinones Structural Classification Microorganisms Source classification Naphthalene Quinones	HIF/HIF Prolyl-Hydroxylase
Fibrostatin F is a proline hydroxylase inhibitor found in Strptomyces catenulae .

HY-N7397

Forsythoside F Arenarioside	Classification of Application Fields Oleaceae Simple Phenylpropanols Source classification Phenols Polyphenols Metabolic Disease Phenylpropanoids Plants Forsythia suspensa (Thunb.) Vahl Disease Research Fields	Xanthine Oxidase
Forsythoside F (Arenarioside) is a xanthine oxidase inhibitor and possesses antihyperuricemic effects in vivo .

HY-W698254

Fluopsin F	Structural Classification Natural Products Microorganisms Source classification	Antibiotic Bacterial
Fluopsin F is an antibiotic containing metallic iron with strong anti-Gram-positive and negative bacteria activity and anti-tumor activity .

HY-N3897

Flavaprin Phellodensin F	Structural Classification Flavonoids Flavonones Source classification Rutaceae Plants Tetradium ruticarpum (A. Jussieu) T. G. Hartley	Others
Flavaprin (Phellodensin F) is a Lignans product that can be isolated from the stem barks of Xanthoxylum piperitum DC. .

HY-P1974

FR 901379 WF11899A	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Antibiotic
FR901379 (WF11899A) is a novel echinocandin-type lipopeptide antibiotic. FR901379 is primarily produced by mutant strain M-7 of Coleophoma empetri F-11899 (FERM BP-2635) .

HY-121431

FR-901235	Structural Classification Microorganisms Source classification Phenols Polyphenols	Fungal
FR-901235 is a new type of immunoactive substance produced by an imperfect fungus, Paecilomyces carneus F-4882. FR-901235 partially restored the impaired delayed-type hypersensitivity to sheep red blood cells in tumor-bearing mice .

HY-N14364

Flavipucine Flavipucin	Structural Classification Natural Products Microorganisms Source classification	Antibiotic Bacterial Parasite
Flavipucine (Flavipucin), a glutarimide antibiotic, is found in the strain of Aspergillus flavipes F-2090/7. Flavipucine has antibacterial activity against B. subtilis. Flavipucine has antiprotozoal activity. Flavipucine has cytotoxic activity against several cancer cells .

HY-N10818

Fipsomin	Structural Classification Source classification Coumarins Phenylpropanoids Plants Moraceae Ficus sarmentosa var. nipponica (Fr.et Sav.)Corner	Others
Fipsomin is a natural product that can be isolated from the fruits of F. nipponica .

HY-N9379

Fissistigine A	Alkaloids Monophenols Classification of Application Fields Goniothalamus amuyon (Bl.) Merr. Source classification Other Diseases Phenols Plants Annonaceae Isoquinoline Alkaloids Disease Research Fields	Others
Fissistigine A is an alkaloid separated of the basic fractions from Formosan Fissistigma glaucescens, F. oldhamii and Goniothalamus amuyon .

HY-Y1309

1-Naphthol Furro ER; NSC 9586; Nako TRB	Structural Classification Monophenols Classification of Application Fields Source classification Other Diseases Phenols Endogenous metabolite Disease Research Fields	Endogenous Metabolite
1-naphthol (Furro ER) is an excited state proton transfer (ESPT) fluorescent molecular probe. 1-naphthol can sense the hydrophobic domains in micellar aggregation and accurately sense the sol-gel transition. 1-naphthol can be used to study the thermally induced microenvironmental changes and hydration levels of Pluronic F127 (PF127) in different microenvironments in aqueous media .

HY-N12604

Penicisteck acid F	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	NF-κB
Penicisteck acid F (Compound 2) is a Marine derived tanzanic acid derivative that is a NF-κB inhibitor. Penicisteck acid F inhibits osteoclast expression by decreasing RANKL-induced IκBα degradation, NF-κB p65 nuclear translocation, NFATc1 activation and nuclear translocation, and related mRNA expression. Penicisteck acid F can be used in osteoporosis research .

HY-N1208

Spiradine F O-Acetylspiradine G; Spiradine G acetate	Structural Classification Alkaloids Pyrrole Alkaloids Source classification Rosaceae Spiraea japonica Plants	Others
Spiradine F is a main alkaloidal component of spiraea japonioa L. fil. Spiradine F derivative can inhibit platelet-activating factor (PAF)-induced platelet aggregation .

HY-113246

15-keto-Prostaglandin F2a 15-keto-PGF2α	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields Endocrinology	Prostaglandin Receptor Endogenous Metabolite
15-keto-Prostaglandin F2α (15-keto-PGF2α) is a metabolite of Prostaglandin F2α. Prostaglandin F2α. Prostaglandin F2α is an orally active, potent prostaglandin F (PGF) receptor (FP receptor) agonist and plays a key role in the onset and progression of labour .

HY-N15473

Isopaucifloral F (±)-Isopaucifloral F	Structural Classification Source classification Phenols Polyphenols Plants Dipterocarpaceae Vatica pauciflora (Korth.) Blume	Estrogen Receptor/ERR Drug Derivative
Isopaucifloral F ((±)-Isopaucifloral F) is a Resveratrol (HY-16561)-derived sesquiterpenes. Isopaucifloral F is an orally active ERβ agonist (EC₅₀: 46.96 μM). Isopaucifloral F has antiosteoporosis activity. LD₅₀ in rats: > 5 mg/kg .

HY-N7223

Lappaol F	Structural Classification Source classification Lignans Phenylpropanoids Plants Compositae Gueldenstaedtia verna (Georgi) Boriss.	YAP Apoptosis
Lappaol F, a lignin, is an anticancer agent. Lappaol F inhibits YAP mRNA and protein level. Lappaol F inhibits tumor cell growth by inducing cell cycle arrest. Lappaol F induces cancer cell apoptosis, and inhibits tumor growth. Lappaol F can be isolated from Arctium lappa Linne (Asteraceae) .

HY-N8619

Minimolide F	Structural Classification Terpenoids Sesquiterpenes Euchresta horsfieldii (Lesch.) J. Benn. Plants Compositae	Others
Minimolide F is a sesquiterpene lactone. Minimolide F has inhibitory activity against human nasopharyngeal cancer cells. Minimolide F can be used for the research of cancer .

HY-N10952

Epicornuin F	Structural Classification Flavonoids Source classification Phenols Epimedium brevicornu Maxim. Plants Berberidaceae Isoflavones	Others
Epicornuin F is a prenylated flavonoid. Epicornuin F can be isolated from the leaves of Epimedium brevicornu. Epicornuin F has the cytotoxic activity against HepG2 cells with an IC₅₀ value of 33.4 μM. Epicornuin F can be used for the research of cancer .

HY-N10380

Inonotusol F	Natural Products Microorganisms Source classification	Others
Inonotusol F is a triterpene isolated from Inonotus obliquus. Inonotusol F shows hepatoprotective effects against D-galactosamine-induced WB-F344 cell damage .

HY-113732

Kazinol F	Structural Classification Source classification Phenols Polyphenols Plants Moraceae Broussonetia papyrifera (Linnaeus) L'Heritier ex Ventenat	SARS-CoV
Kazinol F is a polyphenol from Broussonetia papyrifera. Kazinol F also is an effective Mpro inhibitor. Kazinol F has interaction with both the catalytic residues (His41 and Cys145) of Mpro and exhibits good binding affinity. Kazinol F can be used for the research of COVID-19 .

HY-N14022

Glidobactin F	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Antibiotic Fungal
Glidobactin F is an anti-tumor antibiotic. Glidobactin F has the activity against pathogenic fungi and yeast. Glidobactin F also extends the survival of mice inoculated with leukemia P388 cells .

HY-N14078

Monamycin F	Structural Classification Microorganisms Macrolide Antibiotics Antibiotics Source classification	Antibiotic Bacterial
Monamycin F is an ester peptide antibiotic. Monamycin F has activity against Gram-positive bacteria .

HY-133220A

Guajadial F	Structural Classification Other Monoterpenes Terpenoids Source classification Psidium guajava Linn. Myrtaceae Plants	Others
Guajadial F is a natural product that can be found in Psidium guajava. Guajadial F shows cytotoxicity .

HY-N12241

Sterebin F	Structural Classification Terpenoids Source classification Cassia Diterpenoids Plants Compositae	Others
Sterebin F is a steroid isolated from the Stevia rebaudiana leaves. Sterebin F has hypoglycemic activity .

HY-N0861

Ikarisoside F Ikarisoside-F; Icarisoside-F	Flavonols Flavonoids Classification of Application Fields Source classification Phenols Polyphenols Epimedium brevicornu Maxim. Plants Berberidaceae Disease Research Fields Cancer	Others
Ikarisoside F is a flavonol glycoside from Vancouveria hexandra; could bind to AdoHcy hydrolase.

HY-N13098

Elatoside F	Triterpenes Structural Classification Terpenoids Source classification Aralia elata (Miq.) Seem. Plants Araliaceae	NF-κB
Elatoside F is a triterpenoid saponin with anti-inflammatory activity. Elatoside F inhibits lipopolysaccharide-induced nitric oxide production and nuclear factor NF-κB activation. Elatoside F can be isolated from Aralia elata in one step.

HY-N8386

Berkeleylactone F	Infection Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields	Antibiotic
Berkeleylactone F is an antibiotic macrolide compound. Berkeleylactone F showed modest inhibition of CCRF-CEM leukemia cells .

HY-N10661

Ipomoeassin F Ipom-F	Structural Classification Natural Products Ipomoea squamosa Choisy Plants Convolvulaceae	SARS-CoV
Ipomoeassin F is a potent and selective endoplasmic reticulum (ER) protein-translocation inhibitor by targeting the pore-forming subunit of the Sec61 complex (Sec61α) at the ER membrane. Ipomoeassin F selectively inhibits the ER membrane translocation of SARS-CoV-2 proteins. Ipomoeassin F block the ER translocation of secretory proteins and type I transmembrane proteins (TMPs), but not type III TMPs .

HY-N2241

Hosenkoside F (+)-Hosenkoside F	Triterpenes Structural Classification Classification of Application Fields Terpenoids Impatiens balsamina Linn. Source classification Balsaminaceae Plants Inflammation/Immunology Disease Research Fields	Others
Hosenkoside F is a baccharane glycoside isolated from the seeds of impatiens balsamina.

HY-N3518

Mulberroside F	Structural Classification Monophenols other families Classification of Application Fields Whitening Agent Source classification Phenols Metabolic Disease Cosmetic Research Plants Disease Research Fields	Tyrosinase
Mulberroside F is one of the main bioactive constituents in mulberry (Morus alba L.) . Mulberroside F shows inhibitory effects on tyrosinase activity and on the melanin formation. Mulberroside F also exhibits superoxide scavenging activity that is involved in the protection against auto-oxidation .

HY-N14968

Enniatin F	Structural Classification Natural Products Microorganisms Source classification	Parasite Fungal
Enniatin F has insecticidal and antifungal activity. Enniatin F also can inhibit acyl-CoA, cholesterol acyltransferase (ACAT) .

HY-N14210

Epithienamycin F	Structural Classification Natural Products Microorganisms Source classification	Antibiotic Bacterial
Epithienamycin F is a carbapenem antibiotic. Epithienamycin F has anti-Gram-positive bacteria and anti-Gram-negative bacteria activity .

HY-N3532

Cannabisin F	Structural Classification Monophenols Source classification Phenols Solanaceae Plants Datura metel Linn.	Sirtuin
Cannabisin F is a SIRT1 modulator. Cannabisin F, as a hempseed lignanamide, can be used for the research of anti-inflammatory and anti-oxidative. Cannabisin F may be a potential agent of neurodegenerative diseases as modulators of SIRT1/NF-κB and Nrf2 .

HY-N13926

Arisugacin F	Structural Classification Natural Products Microorganisms Source classification	Cholinesterase (ChE)
Arisugacin F, a microbial metabolite, is a structural analog of Arisugacin A (HY-N13901). Arisugacin F shows no activity against AChE .

HY-N14396

Sannamycin F	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Antibiotic Bacterial
Sannamycin F is an aminoglycoside antibiotic. Sannamycin F has weak antibacterial activity against Gram-positive bacteria and Gram-negative bacteria .

HY-N10766

Ampelopsin F	Structural Classification Vitis coignetiae Source classification Phenols Polyphenols Plants Vitaceae	Others
Ampelopsins F is a bridged plant oligostilbene that can be isolated from Ampelopsis brevipedunculata var. hancei roots. Ampelopsins F is a resveratrol dimer .

HY-N12638

Endolide F	Structural Classification Microorganisms Cyclopeptides Source classification	Vasopressin Receptor
Endolide F (Compound 2) is a proline-containing lactone. Endolide F is a moderate antagonist of the arginine antidiuretic hormone V1A receptor .

HY-N12339

Wulfenioidin F	Structural Classification Terpenoids Labiatae Ambrosia psilostachya DC. Source classification Diterpenoids Plants	Virus Protease
Wulfenioidin F is a diterpenoid, that can be isolated from the whole plant of Orthosiphon wulfenioides. Wulfenioidin F exhibits activity against Zika virus (ZIKV) with an EC₅₀ of 8.07 μM. Wulfenioidin F interferes with the replication of the ZIKV by inhibiting the expression of the ZIKV envelope (E) protein .

HY-N10017

Lucidone F	Triterpenes Structural Classification Microorganisms Terpenoids Source classification	Others
Lucidone F is a nortriterpenoid analogue which is derivated from Ganoderma resinaceum. Lucidone F is promising for research of immune-regulation, hyperglycemia and liver disease .

HY-N15559

Thaigranatumin F	Structural Classification Natural Products Xylocarpus granatum J. Koenig Source classification Plants Meliaceae	Drug Derivative
Thaigranatumin F is a protolimonoid compound found in the seeds of the Thai mangrove (Xylocarpus granatum). Thaigranatumin F is promising for research of neurodegenerative diseases such as Parkinson's diseases .

HY-N13944

Argyrin F	Structural Classification Natural Products Microorganisms Source classification	Apoptosis
Argyrin F a cyclic peptide with antitumoral activities. Argyrin F inhibits cell proliferation, migration, invasion and colony formation by partial induction of apoptosis and epithelial-mesenchymal transition (EMT). Argyrin F stabilizes p27 ^kip, up-regulated p21 ^waf1/cip1 and depletes COX2. Argyrin F can be used for the study of pancreatic ductal adenocarcinoma (PDAC) .

HY-N6036R

Ganoderic acid F (Standard)	Triterpenes Structural Classification Microorganisms Terpenoids Polyporaceae Source classification Ganoderma lucidum (Leyss. Ex Fr.) Karst. Plants	Reference Standards Others
Ganoderic acid F (Standard) is the analytical standard of Ganoderic acid F. This product is intended for research and analytical applications. Ganoderic acid F is a ganoderic acid. Ganoderic acid F exhibits antitumor and antimetastatic activities through inhibition of angiogenesis and alteration of proteins involving cell proliferation and/or cell death, carcinogenesis, oxidative stress, calcium signaling, and endoplasmic reticulum stress .

HY-N6048

Lancifodilactone F	Schisandra lancifolia (Rehd. et Wils.) A. C. Smith Triterpenes Structural Classification Terpenoids Source classification Plants Schisandraceae	HIV
Lancifodilactone F (compound 1) can be isolated from the leaves and stems of Schisandra lancifolia. Lancifodilactone F has anti-HIV activity with EC₅₀=20.69 μg/mL. Lancifodilactone F has cytotoxicity against C8166 cells (CC₅₀ >200 μg/mL) .

HY-N15561

Batzelladine F	Structural Classification Alkaloids Other Alkaloids Marine natural products Source classification Sponge	Parasite
Batzelladine F is a potent *Plasmodium falciparum* inhibitor (IC₅₀ ^3D7= 0.13 μM). Batzelladine F shows moderate cytotoxicity to HepG2 cells (CC₅₀=10.6 μM) with antimalarial properties. Batzelladine F is promising for research of antimalarial agents .

HY-N8174

Valeriandoid F	Structural Classification Valeriana jatamansi Jones Iridoids Classification of Application Fields Terpenoids Source classification Plants Valerianaceae Inflammation/Immunology Disease Research Fields	NO Synthase
Valeriandoid F is an iridoid, which potently inhibits NO production with an IC₅₀ value of 0.88 μM. Valeriandoid F has anti-inflammatory and antiproliferative activities .

HY-N10822

Ajugamarin F4	Structural Classification Portulacaceae Terpenoids Source classification Diterpenoids Plants Portulaca oleracea Linn.	Others
Ajugamarin F4 is a natural product. Ajugamarin F4 can be isolated from the leaves of Ajuga Parviflora .

HY-N5165

Arborcandin F	Structural Classification Natural Products Microorganisms Source classification	Antibiotic Fungal
Arborcandin F is a 1,3-β-glucan synthase inhibitor that serves as an antifungal antibiotic. Arborcandin F exhibits IC₅₀ values of 0.012 μg/mL against both Candida albicans and Aspergillus fumigatus. Additionally, Arborcandin F has an MIC of 2-4 μg/mL against the genus Candida .

HY-125416

Streptothricin F	Microorganisms Source classification	Antibiotic Bacterial
Streptothricin F is a bactericidal antibiotic. Streptothricin F interacts with the 30S subunit of 70S ribosome. Streptothricin F shows rapid, bactericidal activity against highly drug-resistant, carbapenem-resistant Enterobacterales (CRE) (MIC₅₀ and MIC₉₀: 2 and 4 μM, respectively) and Acinetobacter baumannii .

Cat. No.	Product Name	Chemical Structure

HY-12542S

Dantrolene-13C3

Dantrolene- ¹³C₃ is the ¹³C₃ labeled Dantrolene. Dantrolene (F368), a muscle relaxant, non-competitively inhibits human erythrocyte glutathione reductase. Ki and IC50 values are 111.6 μM and 52.3 μM, respectively. Dantrolene is a ryanodine receptor antagonist and Ca2+ signaling stabilizer. Dantrolene can be used for the research of muscle spasticity, malignant hyperthermia, Huntington's disease and other neuroleptic malignant syndrome.

HY-15583S

Auristatin F-d8
Auristatin F-d₈ is deuterium labeled Auristatin F (HY-15583). Auristatin F is a potent cytotoxin in antibo-conjugated agents and an analogue of MMAF. Auristatin F is a potent microtubule inhibitor and vascular damaging agent (VDA). Auristatin F inhibits cell division by preventing tubulin aggregation.Auristatin F can be used in antibody-drug conjugates (ADC) .

HY-B1658BS

Frovatriptan-d3 succinate

Frovatriptan-d₃ (succinate) is deuterium labeled Frovatriptan (succinate). Frovatriptan succinate ((R)-Frovatriptan succinate) is a potent, high affinity, selective and orally active 5-HT1B (pK50 of 8.2) and 5-HT1D receptor agonist. Frovatriptan succinate exhibits >10-fold selectivity for 5-HT1B and 5-HT1D over 5-HT1A, 5-HT1F, and 5-HT7 and >1000-fold selectivity over other 5-HT, dopamine, histamine H1, and α1-adrenoceptor. Frovatriptan succinate has the potential for migraine research .

HY-14794AS

Levomilnacipran-d10 hydrochloride

Levomilnacipran-d₁₀ ((1S,2R)-Milnacipran-d₁₀) hydrochloride is deuterium labeled Levomilnacipran hydrochloride (HY-B0168B). Levomilnacipran ((1S,2R)-Milnacipran) hydrochloride is the enantiomer of Milnacipran (HY-B0168) and a strong substrate of P-gp that can cross the blood-brain barrier. Levomilnacipran hydrochloride is a serotonin and norepinephrine reuptake inhibitor, with IC₅₀ values of 10.5 nM and 19.0 nM, and K_i values of 92.2 nM and 1.2 nM for human norepinephrine transporter (NET) and serotonin transporter (SERT), respectively. Levomilnacipran hydrochloride has antidepressant and anxiolytic activities. Levomilnacipran hydrochloride can be used for the research of depression .

HY-B0168BS

Levomilnacipran-d5 hydrochloride

Levomilnacipran-d5 ((1S,2R)-Milnacipran-d5) hydrochloride is deuterium labeled Levomilnacipran hydrochloride (HY-B0168B). Levomilnacipran ((1S,2R)-Milnacipran) hydrochloride is the enantiomer of Milnacipran (HY-B0168) and a strong substrate of P-gp that can cross the blood-brain barrier. Levomilnacipran hydrochloride is a serotonin and norepinephrine reuptake inhibitor, with IC₅₀ values of 10.5 nM and 19.0 nM, and K_i values of 92.2 nM and 1.2 nM for human norepinephrine transporter (NET) and serotonin transporter (SERT), respectively. Levomilnacipran hydrochloride has antidepressant and anxiolytic activities. Levomilnacipran hydrochloride can be used for the research of depression .

HY-10409S

Fedratinib-d9

Fedratinib-d₉ (TG-101348-d₉) is deuterium labeled Fedratinib. Fedratinib (TG-101348) is a potent, selective, ATP-competitive and orally active JAK2 inhibitor with IC₅₀s of 3 nM for both JAK2 and JAK2V617F kinase. Fedratinib shows 35- and 334-fold selectivity over JAK1 and JAK3, respectively. Fedratinib induces cancer cell apoptosis and has the potential for myeloproliferative disorders research .

HY-113459S

Prostaglandin F1a-d9
Prostaglandin F1a-d₉ is the deuterium labeled Prostaglandin F1a .

HY-114695S

Prostaglandin F2α-1-glyceryl ester-d5
Prostaglandin F2α-1-glyceryl ester-d₅ is the deuterium labeled Prostaglandin F2α-1-glyceryl ester .

HY-113358S

6-keto Prostaglandin F1α-d4
6-keto Prostaglandin F1α-d₄ is the deuterium labeled 6-keto Prostaglandin F1α .

HY-137012S

8-iso Prostaglandin F1α-d9
8-iso Prostaglandin F1α-d₉ is the deuterium labeled 8-iso Prostaglandin F1α .

HY-134178S

5-Fluorouridine 5'-triphosphate-19F
5-Fluorouridine 5'-triphosphate- ¹⁹F is a ¹⁹F labeled 5-Fluorouridine 5'-triphosphate.

HY-113209S1

8-iso Prostaglandin F2α-d9

8-iso Prostaglandin F2α-d₉ is the deuterium labeled 8-Isoprostaglandin F2α. 8-Isoprostaglandin F2α is an isoprostane produced by the non-enzymatic peroxidation of arachidonic acid in membrane phospholipids. 8-Isoprostaglandin F2α is present in human plasma in two distinct forms - esterified in phospholipids and as the free acid. 8-Isoprostaglandin F2α is a weak TP receptor agonist in vascular smooth muscle.

HY-113209S2

8-Isoprostaglandin F2α-13C5

8-Isoprostaglandin F2α- ¹³C₅ is ¹³C labeled 8-Isoprostaglandin F2α (HY-113209). 8-Isoprostaglandin F2α is an isoprostane produced by the non-enzymatic peroxidation of arachidonic acid in membrane phospholipids. 8-Isoprostaglandin F2α is present in human plasma in two distinct forms - esterified in phospholipids and as the free acid. 8-Isoprostaglandin F2α is a weak TP receptor agonist in vascular smooth muscle.

HY-113887S

Prostaglandin F1β-d9
Prostaglandin F1β-d₉ is deuterium labeled Prostaglandin F1β.

HY-W701060

2-Amino-3-Methylimidazo[4,5-f]quinoxaline-d3
2-Amino-3-Methylimidazo[4,5-f]quinoxaline-d₃ is the deuterium labeled 2-Amino-3-Methylimidazo[4,5-f]quinoxaline (HY-W585908).

HY-W281364S

2-Ammo-3-memyl-imidazo-[4,5-f]-quinoIine-13C
2-Ammo-3-memyl-imidazo-[4,5-f]-quinoIine- ¹³C is the ¹³C-labeled 2-Ammo-3-memyl-imidazo-[4,5-f]-quinoIine (HY-W281364). 2-Ammo-3-memyl-imidazo-[4,5-f]-quinoIine is a mutagenic compound .

HY-W014901S1

Bisphenol F-13C12

Bisphenol F- ¹³C₁₂ is the ¹³C labeled Bisphenol F (HY-W014901). Bisphenol F is an orally active endocrine disruptor. Bisphenol F promotes ROS generation, upregulates p-AKT/p-GSK3β, and induces Apoptosis. Bisphenol F interferes with glucose metabolism, affects neurodevelopment and reproductive function. Bisphenol F reduces social novelty preference in mouse offspring. Bisphenol F can be used in bone, blood, and fat-related studies. Bisphenol F is used as a substitute for Bisphenol A (HY-18260) .

HY-W014901S

Bisphenol F-13C6

Bisphenol F- ¹³C₆ is the ¹³C labeled Bisphenol F (HY-W014901). Bisphenol F is an orally active endocrine disruptor. Bisphenol F promotes ROS generation, upregulates p-AKT/p-GSK3β, and induces Apoptosis. Bisphenol F interferes with glucose metabolism, affects neurodevelopment and reproductive function. Bisphenol F reduces social novelty preference in mouse offspring. Bisphenol F can be used in bone, blood, and fat-related studies. Bisphenol F is used as a substitute for Bisphenol A (HY-18260) .

HY-W706319

2-Amino-3-methyl-3H-imidazo[4,5-f]quinoline-d3
2-Amino-3-methyl-3H-imidazo[4,5-f]quinoline-d₃ is deuterium labeled 2-Ammo-3-memyl-imidazo-[4,5-f]-quinoIine. 2-Ammo-3-memyl-imidazo-[4,5-f]-quinoIine is a mutagenic compound .

HY-129953S1

9α,11β-Prostaglandin F2α-d9
9α,11β-Prostaglandin F2α-d₉ is the deuterium labeled 9α,11β-Prostaglandin F2α .

HY-W779193

2-Amino-3-methyl-3H-imidazo[4,5-f]quinoline-2-13C
2-Amino-3-methyl-3H-imidazo[4,5-f]quinoline-2- ¹³C is ¹³C labeled 2-Ammo-3-memyl-imidazo-[4,5-f]-quinoIine. 2-Ammo-3-memyl-imidazo-[4,5-f]-quinoIine is a mutagenic compound .

HY-129953S

9α,11β-Prostaglandin F2α-d4
9α,11β-Prostaglandin F2α-d4 is a deuterated labeled 9α,11β-Prostaglandin F2α . 9α,11β-Prostaglandin F2α is an endogenous metabolite present in Urine that can be used for the research of Asthma .

HY-103447S1

Zearalenone-13C18
Zearalenone- ¹³C₁₈ (Mycotoxin F2- ¹³C₁₈; Toxin F2- ¹³C₁₈) is the ¹³C labeled Zearalenone (HY-103447) . Zearalenone is a mycotoxin produced mainly by fungi belonging to the genus Fusarium in foods and feeds. Possess oestrogenic activity in pigs, cattle and sheep, with low acute toxicity. Causes precocious development of mammae and other estrogenic effects in young gilts .

HY-113459S1

13,14-Dihydro-15-keto Prostaglandin F2α-d4
13,14-Dihydro-15-keto Prostaglandin F2α-d4 (13,14-Dihydro-15-keto-PGF2α-d4) is a deuterated labeled 13,14-Dihydro-15-keto Prostaglandin F2α (HY-113208). 13,14-Dihydro-15-keto Prostaglandin F2α-d4 is an endogenous metabolite present in Blood that can be used for the research of Pregnancy .

HY-W706161

Kresoxim-methyl-d7
Kresoxim-methyl-d₇ (BAS 490 F-d₇) is deuterium labeled Kresoxim-methyl .

HY-113209S

8-Iso-PGF2a-d4
8-Iso-PGF2a-d4 (8-iso Prostaglandin F2α-d4) is an active compound. 8-Iso-PGF2a-d4 can be used the internal standard .

HY-W725077S

Benalaxyl metabolite F4-d9
Benalaxyl metabolite F4-d₉ (Methyl N-(2,6-dimethylphenyl)-N-(formyl)-DL-alaninate-d₉) is deuterium labeled Methyl N-(2,6-dimethylphenyl)-N-formylalaninate .

HY-13631AS1

Exatecan-d3 mesylate
Exatecan-d₃ (DX8951f-d₃) mesylate is deuterium-labeled Exatecan mesylate (HY-13631A). Exatecan mesylate is a DNA topoisomerase I inhibitor, with an IC₅₀ of 0.975 μg/mL .

HY-134178S1

5-Fluorouridine 5'-triphosphate-13C,19F,d1
5-Fluorouridine 5'-triphosphate- ¹³C, ¹⁹F,d₁ is deuterium and ¹³C-labeled 5-Fluorouridine 5'-triphosphate (HY-134178).

HY-129397S

2,3-Dinor-11β-prostaglandin F2α-d9
2,3-Dinor-11β-prostaglandin F2α-d₉ is the deuterium labeled 2,3-Dinor-11β-prostaglandin F2α .

HY-12956S

Dinoprost-d4
Dinoprost-d₄ is the deuterium labeled Dinoprost. Dinoprost (Prostaglandin F2α) is an orally active, potent prostaglandin F (PGF) receptor (FP receptor) agonist. Dinoprost is a luteolytic hormone produced locally in the endometrial luminal epithelium and corpus luteum (CL). Dinoprost plays a key role in the onset and progression of labour .

HY-12956S1

Dinoprost-d9
Dinoprost-d₉ is the deuterium labeled Dinoprost. Dinoprost (Prostaglandin F2α) is an orally active, potent prostaglandin F (PGF) receptor (FP receptor) agonist. Dinoprost is a luteolytic hormone produced locally in the endometrial luminal epithelium and corpus luteum (CL). Dinoprost plays a key role in the onset and progression of labour .

HY-113208AS1

11β-13,14-Dihydro-15-keto Prostaglandin F2α-d4
11β-13,14-Dihydro-15-keto Prostaglandin F2α-d₄ is is the deuterium labeled 11β-13,14-dihydro-15-keto Prostaglandin F2α.

HY-12956S2

Dinoprost-13C5
Dinoprost- ¹³C₅ is ¹³C labeled Dinoprost (HY-12956). Dinoprost (Prostaglandin F2α) is an orally active, potent prostaglandin F (PGF) receptor (FP receptor) agonist. Dinoprost is a luteolytic hormone produced locally in the endometrial luminal epithelium and corpus luteum (CL). Dinoprost plays a key role in the onset and progression of labour .

HY-103447S2

Zearalenone-13C7
Zearalenone- ¹³C₇ (Mycotoxin F2- ¹³C₇) is ¹³C labeled Zearalenone. Zearalenone is a mycotoxin produced mainly by fungi belonging to the genus Fusarium in foods and feeds. Possess oestrogenic activity in pigs, cattle and sheep, with low acute toxicity. Causes precocious development of mammae and other estrogenic effects in young gilts .

HY-13631AS

Exatecan-d5 mesylate
Exatecan-d₅ (DX8951f-d₅) mesylate is deuterium labeled Exatecan mesylate (HY-13631A). Exatecan mesylate is a DNA topoisomerase I inhibitor, with an IC₅₀ of 2.2 μM (0.975 μg/mL). Exatecan mesylate can be used in cancer research .

HY-W754764S

11-(4-Nitrosopiperazin-1-yl)dibenzo[b,f][1,4]thiazepine-d8
11-(4-Nitrosopiperazin-1-yl)dibenzo[b,f][1,4]thiazepine-d₈ (Nitroso aryl piperazine-d₈) is deuterium labeled Nitroso aryl piperazine .

HY-W128969S

5-Bromo-2,4-di-tert-butoxypyrimidine-13C,15N2
5-Bromo-2,4-di-tert-butoxypyrimidine- ¹³C, ¹⁵N₂ (IFLAB-BB F1371-0151- ¹³C, ¹⁵N₂) is the ¹³C- and ¹⁵N-labeled 5-Bromo-2,4-di-tert-butoxypyrimidine (HY-W128969).

HY-114553S

1-(5-Fluoropentyl)-1H-indole-3-carboxylic acid-d5
1-(5-Fluoropentyl)-1H-indole-3-carboxylic acid-d₅ (5F-PB-223-Carboxyindolemetabolite-d₅) is deuterium labeled 1-(5-Fluoropentyl)-1H-indole-3-carboxylic acid .

HY-44745S

4-Ethyl-1,4,7,8-tetrahydro-3H,10H-spiro[pyrano[3,4-f]indolizine-6,2'-[1,3]dioxolane]-3,10-dione-d5
4-Ethyl-1,4,7,8-tetrahydro-3H,10H-spiro[pyrano[3,4-f]indolizine-6,2'-[1,3]dioxolane]-3,10-dione-d5 is the deuterium labeled 4-Ethyl-1,4,7,8-tetrahydro-3H,10H-spiro[pyrano[3,4-f]indolizine-6,2'-[1,3]dioxolane]-3,10-dione .

HY-W779191

MeIQx-13C
MeIQx- ¹³C (2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline-2- ¹³C) is the ¹³C-labeled MeIQx (HY-W355129). MeIQx, a dietary aromatic amine, is mutagenic compound could be isolated from present in fried beef and beef extracts. MeIQx binds covalently to hemoglobin. MeIQx induces liver tumors .

HY-44302S

4'-Ethyl-4'-hydroxy-7',8'-dihydrospiro[[1,3]dioxolane-2,6'-pyrano[3,4-f]indolizine]-3',10'(1'H,4'H)-dione-d5
4'-Ethyl-4'-hydroxy-7',8'-dihydrospiro[[1,3]dioxolane-2,6'-pyrano[3,4-f]indolizine]-3',10'(1'H,4'H)-dione-d₅ is the deuterium labeled 4'-Ethyl-4'-hydroxy-7',8'-dihydrospiro[[1,3]dioxolane-2,6'-pyrano[3,4-f]indolizine]-3',10'(1'H,4'H)-dione .

HY-14648S5

Dexamethasone-d3-1

Dexamethasone-d₃-1 (Hexadecadrol-d₃-1; Prednisolone F-d₃-1) is a deuterium labeled Dexamethasone (HY-14648). Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist. Dexamethasone also significantly decreases CD11b, CD18, and CD62L expression on neutrophils, and CD11b and CD18 expression on monocytes. Dexamethasone is highly effective in the control of COVID-19 infection. Dexamethasone inhibits production of exosomes containing inflammatory microRNA-155 in lipopolysaccharide-induced macrophage inflammatory responses.

HY-W011577S1

Dibenzo[a,c]anthracene-13C6

Dibenzo[a,c]anthracene- ¹³C₆ (2,3-Benzotriphenylene- ¹³C₆) is ¹³C labeled Benzo[f]tetraphene. Benzo[f]tetraphene (Dibenz[a,c]anthracene) is a polycyclic aromatic hydrocarbon with significant antitumor activity. Benzo[f]tetraphene is used as a luminescent probe in cell biology research and can effectively detect reactive oxygen species in biological systems. Benzo[f]tetraphene can also be used as a potential photosensitizer and shows good application prospects in photodynamic inhibition.

HY-169326S

JAK2-IN-11
JAK2-IN-11 (Example 6) is a JAK2 kinase inhibitor with IC₅₀ ≤10 nM against JH2 BIND WT/V617F. JAK2-IN-11 has antitumor activity .

HY-13017S2

Ivacaftor-d18
Ivacaftor-d₁₈ is the deuterium labeled Ivacaftor . Ivacaftor (VX-770) is a potent and orally bioavailable CFTR potentiator, targeting G551D-CFTR and F508del-CFTR with EC₅₀s of 100 nM and 25 nM, respectively .

HY-159578S

VU6036864
VU6036864 (compound 45) is an orally active, selective mAChR M5 antagonist with IC₅₀=20 nM for human M5. VU6036864 is >500-fold selective for human M1-4, with BBB characteristic and high oral bioavailability (%F>100%) .

HY-113437AS

1,2-Dipalmitoyl-sn-glycerol 3-phosphate-d62 sodium
1,2-Dipalmitoyl-sn-glycerol 3-phosphate-d₆₂ (sodium) is deuterium labeled 1,2-Dipalmitoyl-sn-glycerol 3-phosphate. 1,2-Dipalmitoyl-sn-glycerol 3-phosphate sodium (compound 3-F7) is a phosphatidic acid and a human endogenous metabolite .

HY-152066S

Chlorprothixene-d3
Chlorprothixene-d₃ is the deuterium labeled Chlorprothixene Ep Impurity F (HY-Z16039).

HY-13017S4

Ivacaftor-13C6
Ivacaftor- ¹³C₆ (VX-770- ¹³C₆) is ¹³C labeled Ivacaftor. Ivacaftor (VX-770) is a potent and orally bioavailable CFTR potentiator, targeting G551D-CFTR and F508del-CFTR with EC₅₀s of 100 nM and 25 nM, respectively.

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