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Glu

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W016012

**Glu-Glu**	Amino Acid Derivatives	Others
Glu-Glu is a glutamic acid derivative containing amino and carboxyl groups. Glu-Glu is an analogs of acidic tripeptide and can contribute to calcium absorption .

HY-147287

Glu-urea-Glu-NHS ester	PSMA	Cancer
Glu-urea-Glu-NHS ester (compound 21) is an activated N-hydroxysuccinamide (NHS) ester of Glu-urea-Glu which can be used as a pharmacophore for linking with prostate specific membrane antigen (PSMA) inhibitors .

HY-P3960

*(Glu2)-TRH*	Thyroid Hormone Receptor Endogenous Metabolite	Neurological Disease
(Glu2)-TRH, a metabolically stable analogue of Thyrotropin-releasing hormone (TRH; HY-P0002), is a negative modulator for the cholinergic effect of TRH in the mouse brain. (Glu2)-TRH significantly attenuates TRH-induced hippocampal extracellular acetylcholine release. (Glu2)-TRH is not metabolized by thyroliberinase. (Glu2)-TRH manifests neuroprotective, antidepressant, anticonvulsant in the CNS .

HY-P4588

*(Glu17,21,24)-Osteocalcin (1-49) (human)*	GLUT	Metabolic Disease
(Glu17,21,24)-Osteocalcin (1-49) (human) is a bone-specific protein involved in bone formation and glucose metabolism .

HY-159628A

Glu-AMS TEA	Aminoacyl-tRNA Synthetase Bacterial	Infection
Glu-AMS TEA is a competitive inhibitor of Escherichia coli glutamyl-tRNA synthetase (GluRS), with the K_i of 2.8 nM .

HY-E70194

*Endoproteinase Glu-C (MS grade)* V8 protease; Glu-C	Ser/Thr Protease	Others
Endoproteinase Glu-C (MS grade) is a serine proteinase. Endoproteinase GluC is able to hydrolyze some serpins and all classes of mammalian immunoglobulins .

HY-P3794

Glu-Ala-Leu-Phe-Gln-pNA	Virus Protease	Infection
Glu-Ala-Leu-Phe-Gln-pNA is a Chiba virus 3C-like protease (CVP) substrate .

HY-148326

Glu(OtBu)-Val-Cit-PAB-OH	ADC Linker	Others
Glu(OtBu)-Val-Cit-PAB-OH (compound L5-1c) is an non-cleavable ADC linker. Glu(OtBu)-Val-Cit-PAB-OH has been used to synthesis protein-tubulysin conjugates .

HY-P3846

*(Glu20)-Amyloid β-Protein (1-42)*	Amyloid-β	Neurological Disease
(Glu20)-Amyloid β-Protein (1-42) is a slower fibrillizing variant of amyloid β-protein (Aβ). The Glu20 mutation reduces the aggregation propensity of Aβ42 and prevents accumulation of the slowly fibrillizing peptide. Amyloid β-protein is the primary component of both vascular and parenchymal amyloid deposits in Alzheimer's disease .

HY-400878

*Glucocorticoid receptor agonist-1 phosphate Gly-Glu-Mal*	Glucocorticoid Receptor Drug-Linker Conjugates for ADC	Cancer
Glucocorticoid receptor agonist-1 phosphate Gly-Glu-Mal, a glucocorticoid receptor agonist, is a drug-linker conjugate for ADC. Glucocorticoid receptor agonist-1 phosphate Gly-Glu-Mal can be used to synthesize the anti-CD40 antibody agent conjugates (WO2019106608A1; example 9) .

HY-400356

*Glucocorticoid receptor agonist-1 phosphate Gly-Glu* TFA**	ADC Linker	Cancer
Glucocorticoid receptor agonist-1 phosphate Gly-Glu (TFA) is a cleavable linker, that can be used to synthesize Antibody-Drug Conjugates (ADCs).

HY-137883

*Glucocorticoid receptor agonist-1 phosphate Gly-Glu-Br*	Drug-Linker Conjugates for ADC	Cancer
Glucocorticoid receptor agonist-1 phosphate Gly-Glu-Br is a drug-linker conjugate for ADC that can be used to synthesize ABBV-154, ABBV-927, ABBV-368 or their analogs .

HY-P1145

Glucagon-like peptide 1 (1-37), human 1 Publications Verification HuGLP-1	GCGR	Metabolic Disease
Glucagon-like peptide 1 (1-37), human is a highly potent agonist of the GLP-1 receptor.

HY-P1145A

Glucagon-like peptide 1 (1-37), human TFA 1 Publications Verification HuGLP-1 TFA	GCGR	Metabolic Disease
Glucagon-like peptide 1 (1-37), human (TFA) is a highly potent agonist of the GLP-1 receptor.

HY-P5815

GLP-1 (1-36) amide (human, rat) Glucagon-like Peptide 1 (1-36) amide (human, rat)	GLP Receptor GCGR	Metabolic Disease
GLP-1 (1-36) amide (human, rat) (Glucagon-like Peptide 1 (1-36) amide (human, rat) ) is a molecular variant of glucagon-like peptide 1 (GLP-1)-(7-36) amide. GLP-1 (1-36) amide (human, rat) can stimulate [14C]aminopyrine accumulation on enzymatically dispersed enriched rat parietal cells .

HY-P5815A

GLP-1 (1-36) amide (human, rat) TFA Glucagon-like Peptide 1 (1-36) amide (human, rat) TFA	GLP Receptor GCGR	Metabolic Disease
GLP-1 (1-36) amide (human, rat) (Glucagon-like Peptide 1 (1-36) amide (human, rat) ) TFA is a molecular variant of glucagon-like peptide 1 (GLP-1)-(7-36) amide. GLP-1 (1-36) amide (human, rat) TFA can stimulate [14C]aminopyrine accumulation on enzymatically dispersed enriched rat parietal cells .

HY-P0054B

GLP-1(7-36), amide TFA 5+ Cited Publications Glucagon-like peptide-1 (GLP-1)(7-36), amide TFA; Human GLP-1 (7-36), amide TFA	GCGR	Metabolic Disease
GLP-1(7-36), amide TFA is a major intestinal hormone that stimulates glucose-induced insulin secretion from β cells .

HY-P0054

GLP-1(7-36), amide acetate 5+ Cited Publications Glucagon-like peptide-1 (GLP-1)(7-36), amide acetate; Human GLP-1 (7-36), amide acetate	GCGR	Metabolic Disease
GLP-1(7-36), amide acetate is a major intestinal hormone that stimulates glucose-induced insulin secretion from β cells.

HY-P0054A

GLP-1(7-36), amide 5+ Cited Publications Glucagon-like peptide-1 (GLP-1)(7-36), amide; Human GLP-1 (7-36), amide	GCGR	Metabolic Disease
GLP-1(7-36), amide is a physiological incretin hormone that stimulates insulin secretion.

HY-P2535

Glucagon-Like Peptide 1 (GLP-1) (7-36)-Lys (Biotin), amide, human	GLP Receptor	Metabolic Disease
Glucagon-Like Peptide 1 (GLP-1) (7-36)-Lys (Biotin), amide, human is an C-terminal-labelled biotinylated GLP-1 (7-36) amide.

HY-P10972

GIP (22-51) human Glucose-dependent Insulinotropic Peptide (22-51) (human)	NF-κB MMP Calcium Channel	Cardiovascular Disease Neurological Disease
GIP (22-51) human (Glucose-dependent Insulinotropic Peptide (22-51) human) is a potent proatherosclerotic peptide hormone consisting of 30 amino acids. GIP (22-51) human can activate the NF-κB signaling pathway, promote the expression of MMP-8, and induce the expression of proinflammatory and proatherosclerotic proteins. GIP (22-51) human can also increase the level of intracellular free Ca ²⁺ in THP-1-induced macrophages. GIP (22-51) human can be used in the research of atherosclerosis .

HY-P5487

GluR23Y	iGluR	Others
GluR23Y is a biological active peptide. (This GluR23Y peptide was used in ELISA cell-surface assay for the insulin-stimulated endocytosis of native AMPA receptors in cultured hippocampal neurons. GluR23Y prevented any insulin-induced reduction. The blockade of insulin action was observed when the GluR23Y peptide was delivered into neurons by fusing it to the membrane transduction domain of HIV-1.)

HY-P5912

GluN1(356-385)	iGluR	Neurological Disease
GluN1 (356-385) is an antigenic peptide against N-methyl-D-aspartate receptor (NMDAR) encephalitis. GluN1 (356-385) has the effect of reducing the density of surface NMDAR clusters in hippocampal neurons. GluN1 (356-385) can be used to study the pathogenesis of anti-NMDAR encephalitis .

HY-P1841

Glucagon-Like Peptide (GLP) II, human	Endogenous Metabolite Apoptosis	Metabolic Disease
Glucagon-Like Peptide (GLP) II, human is a 33-amino acid peptide derived from the C-terminal of proglucagon and mainly produced by the intestinal L cells. Glucagon-Like Peptide (GLP) II, human stimulates intestinal mucosal growth and decreases apoptosis of enterocytes .

HY-P1024

GLP-2(1-33)(human) GLP-2 (human); Glucagon-like peptide 2 (human)	GCGR	Metabolic Disease
GLP-2(1-33) (human) is an enteroendocrine hormone which can bind to the GLP-2 receptor and stimulate the growth of intestinal epithelium.

HY-122259

AMPte-Glu-γ-Glu	Antifolate	Cancer
AMPte-Glu-γ-Glu is a substrate for folylpoly-γ-glutamate synthetase (FPGS). AMPte-Glu-γ-Glu exhibits cytotoxicity against chinese hamster ovaries cells, with IC₅₀s of 20, 350 and 3 nM, for Pro3, R2, and 43-10, respectively .

HY-P4632

*H-γ-Glu-Leu-OH* 1 Publications Verification γ-Glu-Leu	Amino Acid Derivatives	Others
H-γ-Glu-Leu-OH (γ-Glu-Leu) is a dipeptide consisting of γ-glutamic acid and leucine, terminated by a hydroxyl group .

HY-P1200

*Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH*	Src	Cancer
Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH (compound 1) is a high-affinity pentapeptide to bind to the src SH2 domain (IC₅₀≈1 µM). Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH is an inhibitor for src SH3-SH2:phosphoprotein interactions .

HY-P3218A

*[Glu4]-Oxytocin acetate*	Drug Derivative	Endocrinology
[Glu4]-Oxytocin acetate is an appropriate derivative of oxytocin for conducting a comprehensive investigation by a variety of methods of the conformation of oxytocin-like molecules in aqueous solution .

HY-P3218

*[Glu4]-Oxytocin*	Oxytocin Receptor	Endocrinology
[Glu4]-Oxytocin is an appropriate derivative of oxytocin for conducting a comprehensive investigation by a variety of methods of the conformation of “oxytocin-like” molecules in aqueous solution .

HY-P1200A

*Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH TFA*	Src	Cancer
Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH TFA (compound 1) is a high-affinity pentapeptide to bind to the src SH2 domain (IC₅₀≈1 µM). Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH TFA is an inhibitor for src SH3-SH2:phosphoprotein interactions .

HY-137286

*Z-Leu-Leu-Glu-βNA* Z-Leu-Leu-Glu-β-naphthylamide	Proteasome	Others
Z-Leu-Leu-Glu-βNA (Z-Leu-Leu-Glu-β-naphthylamide) is a substrate for determination of the glutamylpeptidyl-peptide hydrolase activity of the 20S proteasome .

HY-P4376A

*Gamma-Glu-Abu TFA*	CaSR	Neurological Disease
Gamma-Glu-Abu TFA is the TFA salt form of Gamma-Glu-Abu (HY-P4376). Gamma-Glu-Abu TFA is an agonist for calcium sensing receptor (CaSR), that activates the CaSR with an EC₅₀ of 0.21 μM in HEK-293 cell .

HY-P1143

*[Des-His1,Glu9]-Glucagon amide*	GCGR	Metabolic Disease
[Des-His1,Glu9]-Glucagon amide is a potent and peptide antagonist of the glucagon receptor, with a pA₂ of 7.2. [Des-His1,Glu9]-Glucagon amide is potentially useful in the study of the pathogenesis of diabetes .

HY-P4243

*Dansyl-Glu-Gly-Arg-Chloromethylketone*	Ser/Thr Protease	Others
Dansyl-Glu-Gly-Arg-Chloromethylketone is a protease inhibitor, and inhibits serine/threonine proteases. Dansyl-Glu-Gly-Arg-Chloromethylketone inhibits activated porcine factor IX .

HY-145779

*H-Glu(Met-OH)-OH* γ-Glu-Met	Biochemical Assay Reagents	Metabolic Disease
H-Glu(Met-OH)-OH (γ-Glu-Met) could induce oxidation of hydroxyl radical .

HY-W099578

*Pal-Glu(OSu)-OtBu* Palmitoyl-Glu(OSu)-OBut	Drug Intermediate	Others
Pal-Glu(OSu)-OtBu (Palmitoyl-Glu(OSu)-OBut) is an important intermediate in the synthesis process of Liraglutide (HY-P0014) .

HY-P0308

*[Glu1]-Fibrinopeptide B*	Drug Intermediate	Cardiovascular Disease
[Glu1]-Fibrinopeptide B is derived from fibrinopeptide B amino acid residues 1-14. Human fibrinopeptide B (hFpB), a thrombin-derived proteolytic cleavage product of the fibrinogen B beta-chain, to stimulate neutrophils (PMN), monocytes, and fibroblasts.

HY-P1143A

*[Des-His1,Glu9]-Glucagon amide TFA*	GCGR	Metabolic Disease
[Des-His1,Glu9]-Glucagon amide TFA is a potent and peptide antagonist of the glucagon receptor, with a pA₂ of 7.2. [Des-His1,Glu9]-Glucagon amide TFA is potentially useful in the study of the pathogenesis of diabetes .

HY-117483

Gly-Pro-Glu	iGluR	Neurological Disease
Gly-Pro-Glu is a neuroactive peptide with a potent action on acetylcholine release. Gly-Pro-Glu is the N-terminal tripeptide of insulin-like growth factor-I. Gly-Pro-Glu inhibits glutamate binds to N-methyl-D-aspartate (NMDA) receptor with an IC₅₀ value of 14.7 μM. Gly-Pro-Glu can be used for the research of neuroprotection .

HY-W011075

*Z-D-Glu-Obzl*	Amino Acid Derivatives	Others
Z-D-Glu-Obzl is a derivative of D-Glu, can be used for synthesis of compounds .

HY-35028

*Boc-Glu-Ofm*	Amino Acid Derivatives	Others
Boc-Glu-Ofm is a peptide. Boc-Glu-Ofm has been used for the synthesis of ester insulin and cyclic peptide mixtures .

HY-P4243A

*Dansyl-Glu-Gly-Arg-Chloromethylketone TFA*	Ser/Thr Protease	Others
Dansyl-Glu-Gly-Arg-Chloromethylketone TFA is a protease inhibitor, and inhibits serine/threonine proteases. Dansyl-Glu-Gly-Arg-Chloromethylketone TFA inhibits activated porcine factor IX .

HY-146343

BMI-Glu	Fluorescent Dye γ-Glutamyl Transferase (GGT)	Inflammation/Immunology Cancer
BMI-Glu is a selective γ-glutamyl transpeptidase (GGT) fluorescent probe with a K_m of 69.63 µM. BMI-Glu has high sensitivity, good water solubility and biocompatibility .

HY-P11200

*γ-Glu-Asn* γ-Glutamylasparagine	Calcium Channel	Neurological Disease
γ-Glu-Asn (γ-Glutamylasparagine) is a calcium sensing receptor (CaSR) agonist. γ-Glu-Asn is a dipeptide composed of glutamic acid and asparagine .

HY-P3608

*[Des-His1,Glu9] Glucagon*	GCGR	Metabolic Disease
[Des-His1,Glu9] Glucagon is a potent glucagon receptor system peptide antagonist. [Des-His1,Glu9] Glucagon enhances the glucose-stimulated release of insulin from pancreatic islet cells. [Des-His1,Glu9] Glucagon can be used to research diabetes .

HY-N11598

α-GLU	Others	Metabolic Disease
α-GLU stands for α-glucosidase. α-GLU hydrolyzes starch and disaccharides via targeting to terminal, non-reducing (1→4)-linked α-D-glucose residues to produce α-glucose. α-GLU is substrate selective .

HY-W013678R

*H-Glu(OMe)-OH (Standard)*	Amino Acid Derivatives Reference Standards	Others
H-Glu(OMe)-OH (Standard) is the analytical standard of H-Glu(OMe)-OH. This product is intended for research and analytical applications. H-Glu(OMe)-OH is a glutamic acid derivative .

HY-174300

Cholic acid-Glu	Pregnane X Receptor (PXR)	Metabolic Disease
Cholic acid-Glu is a derivative of Cholic acid (HY-N0324). The abundance of Cholic acid-Glu is increased in Crohn’s disease. Cholic acid-Glu increases PXR activation and significantly increases the expression of the downstream PXR target gene Cyp3a11 in small intestinal organoid tissue .

HY-W041988

*Fmoc-Glu-OMe*	Bacterial	Infection
Fmoc-Glu-OMe, a glutamic acid derivative, shows antibacterial activity and gelation property in AgNO₃ solution. Fmoc-Glu-OMe is a mouldable wound healing biomaterial .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-P3960

*(Glu2)-TRH*	Natural Products Neurological Disease Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	Thyroid Hormone Receptor Endogenous Metabolite
(Glu2)-TRH, a metabolically stable analogue of Thyrotropin-releasing hormone (TRH; HY-P0002), is a negative modulator for the cholinergic effect of TRH in the mouse brain. (Glu2)-TRH significantly attenuates TRH-induced hippocampal extracellular acetylcholine release. (Glu2)-TRH is not metabolized by thyroliberinase. (Glu2)-TRH manifests neuroprotective, antidepressant, anticonvulsant in the CNS .

HY-101399

*γ-Glu-Phe* γ-Glutamylphenylalanine	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
γ-Glu-Phe (γ-Glutamylphenylalanine) is synthesized by Bacillus amyloliquefaciens (GBA) and Aspergillus oryzae (GAO). γ-Glu-Phe or the post-enzymatic reaction mixture enhances the umami intensity of commercial soy sauce and model chicken broth .

HY-P3280

*γ-Glu-Gly*	Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
γ-Glu-Gly, a γ-glutamyl dipeptide, is a human lipid metabolite.γ-Glu-Gly has a similar structure to GABA (γ-aminobutyric acid) and can act as an antagonist of excitatory amino acids .

HY-101399A

*γ-Glu-Phe TFA* γ-Glutamylphenylalanine TFA	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Disease Research Fields	Endogenous Metabolite
γ-Glu-Phe TFA (γ-Glutamylphenylalanine TFA) is synthesized by Bacillus amyloliquefaciens (GBA) and Aspergillus oryzae (GAO). γ-Glu-Phe TFA or the post-enzymatic reaction mixture enhances the umami intensity of commercial soy sauce and model chicken broth .

HY-113003

*H-γ-Glu-Gln-OH* γ-GlutamylGlutamine; γ-Glu-Gln	Animals Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Others
H-γ-Glu-Gln-OH is a hydrophilic peptide and can be conjugated to drugs. The carrier composed of H-γ-Glu-Gln-OH has the characteristics of high water solubility and drug-loading capacity, good biocompatibility, low toxicity, improved tumor targeting ability, and anti-tumor efficacy .

HY-113083

Acetaminophen glucuronide APAP-Glu	Alkaloids Classification of Application Fields Other Alkaloids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Drug Metabolite Endogenous Metabolite
Acetaminophen glucuronide (APAP-glu) is an inactive glucuronide metabolite of Acetaminophen (HY-66005) . Acetaminophen is a selective cyclooxygenase-2 (COX-2) inhibitor and a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor .

HY-N11140

Glu-Lys	Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Others
Glu-Lys is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P1841

Glucagon-Like Peptide (GLP) II, human	Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite Apoptosis
Glucagon-Like Peptide (GLP) II, human is a 33-amino acid peptide derived from the C-terminal of proglucagon and mainly produced by the intestinal L cells. Glucagon-Like Peptide (GLP) II, human stimulates intestinal mucosal growth and decreases apoptosis of enterocytes .

HY-P3280A

*γ-Glu-Gly TFA*	Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
γ-Glu-Gly TFA, a γ-glutamyl dipeptide, is a human lipid metabolite.γ-Glu-Gly TFA has a similar structure to GABA (γ-aminobutyric acid) and can act as an antagonist of excitatory amino acids .

HY-N12622

AChE-IN-58	Flavonoids Flavones Source classification Camellia sinensis (L.) O. Ktze. Plants Theaceae	Cholinesterase (ChE)
AChE-IN-58 (Compound 3) is an acetylcholinesterase (AChE) inhibitor. AChE-IN-58 can extend the mean lifespan, delay the Aβ₁-42-induced paralysis, enhanc the locomotion, and alleviate glutamic acid (Glu)-induced neurotoxicity of CL4176 worms .

HY-113083R

Acetaminophen glucuronide (Standard) APAP-Glu (Standard)	Alkaloids Other Alkaloids Source classification Endogenous metabolite	Reference Standards Drug Metabolite Endogenous Metabolite
Acetaminophen glucuronide (Standard) is the analytical standard of Acetaminophen glucuronide. This product is intended for research and analytical applications. Acetaminophen glucuronide (APAP-glu) is an inactive glucuronide metabolite of Acetaminophen (HY-66005) . Acetaminophen is a selective cyclooxygenase-2 (COX-2) inhibitor and a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor .

HY-113089A

Epsilon-(gamma-glutamyl)-lysine TFA H-Glu(H-Lys-OH)-OH TFA; γ-Glu-ε-Lys TFA	Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Epsilon-(gamma-glutamyl)-lysine (H-Glu(H-Lys-OH)-OH) TFA is an N(6)-acyl-L-lysine derivative. The enzyme tissue transglutaminase (tTg) helps the formation of epsilon-(gamma-glutamyl)lysine bonds between ECM components in some disease, such as non-diabetic kidney, glaucoma filtration .

HY-13718

Oglufanide H-Glu-Trp-OH; L-Glutamyl-L-tryptophan	Cardiovascular Disease Classification of Application Fields Animals Ketones, Aldehydes, Acids Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	VEGFR HCV Endogenous Metabolite
Oglufanide (H-Glu-Trp-OH) is a dipeptide immunomodulator isolated from calf thymus. Oglufanide inhibits vascular endothelial growth factor (VEGF). Oglufanide can stimulate the immune response to hepatitic C virus (HCV) and intracellular bacterial infections. Oglufanide shows antitumor and anti-angiogenesis activities .

HY-112171

γ-L-Glutamyl-L-alanine 1 Publications Verification γ-Glu-Ala	Natural Products Human Gut Microbiota Metabolites Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite CaSR
γ-L-Glutamyl-L-alanine (γ-Glu-Ala), composed of gamma-glutamate and alanine, is a proteolytic breakdown product of larger proteins. γ-L-Glutamyl-L-alanine is a natural substrate of the γ-Glutamylcyclotransferase. γ-L-Glutamyl-L-alanine is a positive modulator of calcium-sensing receptor (CaR) function .

HY-113089

Epsilon-(gamma-glutamyl)-lysine H-Glu(H-Lys-OH)-OH; γ-Glu-ε-Lys	Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Epsilon-(gamma-glutamyl)-lysine is an N(6)-acyl-L-lysine derivative. The enzyme tissue transglutaminase (tTg) helps the formation of epsilon-(gamma-glutamyl)lysine bonds between ECM components in some disease, such as non-diabetic kidney, glaucoma filtration .

HY-113402

Gamma-glutamylcysteine 3 Publications Verification γ-Glu-Cys	Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite
Gamma-glutamylcysteine (γ-Glutamylcysteine), a dipeptide containing cysteine and glutamic acid, is a precursor to glutathione (GSH). Gamma-glutamylcysteine is a cofactor for glutathione peroxidase (GPx) to increase GSH levels .

HY-101399R

*γ-Glu-Phe (Standard)* γ-Glutamylphenylalanine (Standard)	Microorganisms Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Reference Standards Endogenous Metabolite
Ceftezole (sodium) (Standard) is the analytical standard of Ceftezole (sodium). This product is intended for research and analytical applications. Ceftezole sodium (CTZ sodium) is a broad-spectrum cephem antibiotic against many species of gram-positive and gram-negative bacteria. Ceftezole sodium (CTZ sodium) is an alpha-glucosidase inhibitor with in vivo anti-diabetic activity .

HY-113402R

Gamma-glutamylcysteine (Standard) γ-Glu-Cys (Standard)	Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Reference Standards Endogenous Metabolite
Gamma-glutamylcysteine (Standard) is the analytical standard of Gamma-glutamylcysteine. This product is intended for research and analytical applications. Gamma-glutamylcysteine (γ-Glutamylcysteine), a dipeptide containing cysteine and glutamic acid, is a precursor to glutathione (GSH). Gamma-glutamylcysteine is a cofactor for glutathione peroxidase (GPx) to increase GSH levels .

HY-N10477

gamma-Glutamylarginine L-γ-Glutamyl-L-arginine; γ-Glu-Arg	Panax ginseng C. A. Meyer Natural Products Classification of Application Fields Source classification Other Diseases Plants Disease Research Fields Araliaceae	Amino Acid Derivatives
gamma-Glutamylarginine (L-γ-Glutamyl-L-arginine), an γ-glutamic acid oligopeptide, can be isolated from Panax ginseng .

HY-112171R

γ-L-Glutamyl-L-alanine (Standard) γ-Glu-Ala (Standard)	Natural Products Human Gut Microbiota Metabolites Source classification Endogenous metabolite	Endogenous Metabolite CaSR
γ-L-Glutamyl-L-alanine (Standard) is the analytical standard of γ-L-Glutamyl-L-alanine. This product is intended for research and analytical applications. γ-L-Glutamyl-L-alanine, composed of gamma-glutamate and alanine, is a proteolytic breakdown product of larger proteins. γ-L-Glutamyl-L-alanine is a natural substrate of the γ-Glutamylcyclotransferase. γ-L-Glutamyl-L-alanine is a positive modulator of calcium-sensing receptor (CaR) function .

HY-N0240

Herbacetin 4 Publications Verification	Flavonols Flavonoids Linum usitatissimum Linn. Classification of Application Fields Linaceae Source classification Phenols Polyphenols Plants Disease Research Fields Cancer	Ornithine decarboxylase (ODC)
Herbacetin is a natural flavonoid from flaxseed, exerts various pharmacological activities, including antioxidant, anti-inflammatory and anticancer effects . Herbacetin is an Ornithine decarboxylase (ODC) allosteric inhibitor, directly binds to Asp44, Asp243, and Glu384 on ODC. Ornithine decarboxylase (ODC) is a rate-limiting enzyme in the first step of polyamine biosynthesis .

HY-N0240R

Herbacetin (Standard)	Flavonols Flavonoids Linum usitatissimum Linn. Linaceae Source classification Phenols Polyphenols Plants	Reference Standards Others
Herbacetin (Standard) is the analytical standard of Herbacetin. This product is intended for research and analytical applications. Herbacetin is a natural flavonoid from flaxseed, exerts various pharmacological activities, including antioxidant, anti-inflammatory and anticancer effects . Herbacetin is an Ornithine decarboxylase (ODC) allosteric inhibitor, directly binds to Asp44, Asp243, and Glu384 on ODC. Ornithine decarboxylase (ODC) is a rate-limiting enzyme in the first step of polyamine biosynthesis .

HY-113089AR

Epsilon-(gamma-glutamyl)-lysine TFA (Standard)	Natural Products Source classification Endogenous metabolite	Endogenous Metabolite
Epsilon-(gamma-glutamyl)-lysine (TFA) (Standard) is the analytical standard of Epsilon-(gamma-glutamyl)-lysine (TFA). This product is intended for research and analytical applications. Epsilon-(gamma-glutamyl)-lysine (H-Glu(H-Lys-OH)-OH) TFA is an N(6)-acyl-L-lysine derivative. The enzyme tissue transglutaminase (tTg) helps the formation of epsilon-(gamma-glutamyl)lysine bonds between ECM components in some disease, such as non-diabetic kidney, glaucoma filtration .

HY-N15365

Antcin B	Microorganisms Ketones, Aldehydes, Acids Source classification	Virus Protease SARS-CoV
Antcin B is a SARS-CoV-2 3-chymotrypsin-like protease (3CL Pro) inhibitor. Antcin B binds to multiple key amino acid residues of 3CL Pro(such as Leu141, Asn142, Glu166, His163, etc.) through hydrogen bonds, salt bridges, and hydrophobic interactions, thereby inhibiting the activity of 3CL Pro, blocking the cleavage process of viral polyproteins, and suppressing the replication of the SARS-CoV-2 virus in host cells. Antcin B is promising for research of COVID-19 .

HY-P1543

Exendin-3	Natural Products Animals Source classification	GLP Receptor Amylases GCGR
Exendin-3 is a biologically active peptides isolated from venoms of the Gila monster lizards, Heloderma horridurn.

HY-P5708

Adenoregulin Dermaseptin b2	Animals Ketones, Aldehydes, Acids Source classification	Antibiotic Fungal Bacterial
Adenoregulin (Dermaseptin b2) is an antimicrobial peptide antibiotic. Adenoregulin is active against Gram-negative and Gram-positive bacteria, yeast and fungi. Adenoregulin also enhances the binding of agonists to the A1 adenosine receptor .

HY-P1189

Echistatin	Natural Products Animals Classification of Application Fields Source classification Inflammation/Immunology Disease Research Fields	Integrin
Echistatin, the smallest active RGD protein belonging to the family of disintegrins that are derived from snake venoms, is a potent inhibitor of platelet aggregation. Echistatin is a potent inhibitor of bone resorption in culture. Echistatin is a potent antagonist of α_IIbβ₃, α_vβ₃ and α₅β₁ .

HY-P1189A

Echistatin TFA	Natural Products Animals Classification of Application Fields Source classification Metabolic Disease Inflammation/Immunology Disease Research Fields	Integrin
Echistatin TFA, the smallest active RGD protein belonging to the family of disintegrins that are derived from snake venoms, is a potent inhibitor of platelet aggregation. Echistatin is a potent inhibitor of bone resorption in culture. Echistatin is a potent antagonist of α_IIbβ₃, α_vβ₃ and α₅β₁ .

HY-P3055

Dendrotoxin-I DTX-I	Animals Cyclopeptides Source classification Animal Venoms	Potassium Channel
Dendrotoxin-I (DTX-I) is a potent K ⁺ channels blocker with IC₅₀s of 0.13-50 nM for voltage-gated potassium channel subunits K_V1.1, K_V1.2 and K_V1.6, respectively. Dendrotoxin-I, a neurotoxin, has the potential for cancer research .

HY-P5719

Andropin	Animals Ketones, Aldehydes, Acids Source classification	Bacterial
Andropin is a male-specific antibacterial peptide that can be found in Drosophila melanogaster .

HY-P0017

Aprotinin Maximum Cited Publications 27 Publications Verification	Cardiovascular Disease Natural Products Animals Source classification Disease Research Fields	Influenza Virus Ser/Thr Protease
Aprotinin is a bovine pancreatic trypsin inhibitor (BPTI) inhibitor which inhibits trypsin and chymotrypsin with K_is of 0.06 pM and 9 nM, respectively.

HY-P3065

Calcicludine	Natural Products Animals Source classification	Calcium Channel
Calcicludine is a protein toxin from the venom of the green mamba that inhibits high-voltage-activated calcium channel, especially L-type calcium channel .

HY-P5699

Cyclopetide 2	Animals Ketones, Aldehydes, Acids Source classification	Bacterial
Cyclopetide 2 (Compound 2) is an antimicrobial peptide with moderate activity against B. subtilis, with a MIC of 50 μg/mL .

HY-P5698

Cyclopetide 1	Animals Ketones, Aldehydes, Acids Source classification	Bacterial
Cyclopetide 1 (Compound 1) is an antimicrobial peptide with moderate activity against B. subtilis, with a MIC of 25 μg/mL .

HY-105174

BPC 157	Alkaloids Pyrrole Alkaloids Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	JAK FAK
BPC 157 is the 15-amino acide fragment of gastric peptide BPC. BPC 157 exhibits wound healing promoting and neuroprotective activity. BPC 157 maintains the integrity of the gastrointestinal mucosa without significant toxicity. BPC 157 acetate counteracts NSAIDs/insulin overdose/copper-induced toxicity. BPC 157 ameliorates specific (over)stimulated/damaged neurotransmitter systems-induced behavioral disorders through serotonergic and dopaminergic systems .

HY-N6708

Alamethicin 1 Publications Verification	Infection Microorganisms Classification of Application Fields Antibiotics Source classification Mammalian Cell Culture Antibacterial Disease Research Disease Research Fields Other Antibiotics	Antibiotic Bacterial
Alamethicin is a linear 20-amino acid antibiotic, which can induce voltage-gated conductance in model and cell membranes. Alamethicin exhibits antimicrobial activity against Gram-positive bacteria, but not Gram-negative bacteria. Alamethicin can form an amphipathic α-helical structure in biological membranes .

HY-B0108

Daptomycin 20+ Cited Publications LY146032	Infection Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Mammalian Cell Culture Antibacterial Disease Research Disease Research Fields	Bacterial Antibiotic
Daptomycin is a lipopeptide antibiotic with rapid in vitro bactericidal activity against gram-positive organisms.

HY-P0269

Magainin 1 Magainin I	Infection Natural Products Animals Classification of Application Fields Source classification Disease Research Fields	Bacterial Fungal Antibiotic
Magainin 1 (Magainin I) is an antimicrobial and amphipathic peptide isolated from the skin of Xenopus laevis. Magainin 1 exhibits antibiotic activity against numerous Gram-negative and Gram-positive bacteria .

HY-P0269A

Magainin 1 TFA Magainin I TFA	Infection Natural Products Animals Classification of Application Fields Source classification Disease Research Fields	Bacterial Fungal Antibiotic
Magainin 1 TFA (Magainin I TFA) is an antimicrobial and amphipathic peptide isolated from the skin of Xenopus laevis. Magainin 1 TFA exhibits antibiotic activity against numerous Gram-negative and Gram-positive bacteria .

HY-P0270

Magainin 2 Magainin II	Infection Natural Products Animals Classification of Application Fields Source classification Disease Research Fields	Bacterial Antibiotic Fungal
Magainin 2 (Magainin II) is an antimicrobial peptide (AMP) isolated from the skin of the African clawed frog Xenopus laevis. Magainin 2 displays antibiotic activity against numerous gram-negative and gram-positive bacteria. Magainin 2 also is active against protozoa . Magainin 2 exerts its cytotoxicity effects by preferential interactions with anionic phospholipids abundant in bacterial membranes .

HY-P2358

PSMα3	Natural Products Microorganisms Classification of Application Fields Source classification Inflammation/Immunology Disease Research Fields	Toll-like Receptor (TLR)
PSMα3 is a peptide for manipulating DCs to become tolerogenic for DC vaccination strategies. PSMα3 penetrates and modulates human monocyte-derived DCs by altering the TLR2- or TLR4-induced maturation, inhibiting pro- and anti-inflammatory cytokine production and reducing antigen uptake. PSMα3 is an important toxin released by the most virulent strains of methicillin-resistant Staphylococcus aureus (MRSA) .

HY-P0259

Xenin	Natural Products Source classification Endogenous metabolite	Endogenous Metabolite
Xenin is a 25-amino acid peptide initially isolated from human gastric mucosa. Xenin is a gut hormone that can reduce food intake.

HY-P5670

Maximin 31	Animals Ketones, Aldehydes, Acids Source classification	Bacterial
Maximin 31 is an antimicrobial peptide derived from the toad brain. Maximin 31 is active against Staphylococcus aureus and Escherichia coli, with MIC values of 37.5, 75 μg/mL, respectively .

HY-P5682

Maximin 41	Animals Ketones, Aldehydes, Acids Source classification	Bacterial
Maximin 41 is an antimicrobial peptide. Maximin 41 has antibacterial activity against S. aureus (MIC: 75 μg/mL). Maximin 41 has hemolytic activities against human red cells .

HY-P5692

Maximin 77	Animals Ketones, Aldehydes, Acids Source classification	Bacterial
Maximin 77 is an antimicrobial peptide. Maximin 77 has antibacterial activity against S. aureus (MIC: 18.8 μg/mL). Maximin 77 has hemolytic activities against human red cells .

HY-P5689

Maximin 42	Animals Ketones, Aldehydes, Acids Source classification	Bacterial
Maximin 42 is an antimicrobial peptide. Maximin 42 has antibacterial activity against S. aureus (MIC: 37.5 μg/mL). Maximin 42 has hemolytic activities against human red cells .

HY-P5685

Maximin 49	Animals Ketones, Aldehydes, Acids Source classification	Bacterial
Maximin 49 is an antimicrobial peptide. Maximin 49 has antibacterial activity against S. aureus (MIC: 18.8 μg/mL). Maximin 49 has hemolytic activities against human and rabbit red cells .

HY-P5621

Maximin 63	Animals Ketones, Aldehydes, Acids Source classification	Bacterial
Maximin 63 is an antimicrobial peptide derived from the brain of a toad. Maximin 63 has strong activity against S.aureus (MIC: 18.8 μg/mL) .

HY-P5683

Maximin 45	Animals Ketones, Aldehydes, Acids Source classification	Bacterial
Maximin 45 is an antimicrobial peptide. Maximin 41 has antibacterial activity against S. aureus, E. coli, B. subtilis (MIC: 4.7, 9.4, 75 μg/mL). Maximin 45 has hemolytic activities against human and rabbit red cells .

HY-P5671

Maximin 32	Animals Ketones, Aldehydes, Acids Source classification	Bacterial
Maximin 32 is an antimicrobial peptide derived from the toad brain. Maximin 32 is active against Staphylococcus aureus and Escherichia coli, with MIC values of 9.4, 18.8 μg/mL, respectively .

Cat. No.	Product Name	Chemical Structure

HY-W015241S

*Ac-D-Glu-OH-d5*
Ac-D-Glu-OH-d₅ is the deuterium labeled Ac-D-Glu-OH.

HY-101399SA

*γ-Glu-(Phe-13C9,15N) TFA*
γ-Glu-(Phe-13C9,15N) (γ-Glutamylphenylalanine-13C9,15N) TFA is the ¹³C- and ¹⁵N-labeled γ-Glu-Phe TFA (HY-101399A). γ-Glu-Phe TFA is synthesized by Bacillus amyloliquefaciens (GBA) and Aspergillus oryzae (GAO). γ-Glu-Phe TFA or the post-enzymatic reaction mixture enhances the umami intensity of commercial soy sauce and model chicken broth .

HY-141902S

*Fmoc-Glu(OtBu)-OH-13C5,15N*
FMOC-L-Glutamic Acid- ¹³C₅, ¹⁵N-5-t-butyl ester is the ¹³C and ¹⁵N labeled FMOC-L-Glutamic Acid-5-t-butyl ester .

HY-70057S1

Safinamide-d4-1

Safinamide-d₄-1 is deuterium labeled Safinamide. Safinamide is a potent, selective, and reversible monoamine oxidase B (MAO-B) inhibitor (IC₅₀=0.098 μM) over MAO-A (IC₅₀=580 μM) . Safinamide also blocks sodium channels and modulates glutamate (Glu) release, showing a greater affinity at depolarized (IC₅₀=8?μM) than at resting (IC₅₀=262?μM) potentials. Safinamide has neuroprotective and neurorescuing effects and can be used for the study of parkinson disease, ischemia stroke etc.al .

HY-Y0134S

*Fmoc-Glu(OtBu)-OH-15N*
Fmoc-Glu(OtBu)-OH- ¹⁵N is a ¹⁵N-labeled Fmoc-Glu(OtBu)-OH .

HY-101399S

*γ-Glu-(Phe-13C9,15N)*
γ-Glu-(Phe- ¹³C9, ¹⁵N) is the ¹³C and ¹⁵N labeled isotope of γ-Glu-Phe(HY-101399).γ-Glu-Phe or the postenzymatic reaction mixture enhanced the umami intensity of commercial soy sauce and model chicken soup.

HY-W777099

*N-Cbz-O-Bzl-L-Glu-S-Bzl-L-Cys-Gly[13C2,15N]-OBzl*
N-Cbz-O-Bzl-L-Glu-S-Bzl-L-Cys-Gly[ ¹³C₂, ¹⁵N]-OBzl is the ¹³C- and ¹⁵N-labeled N-Cbz-O-Bzl-L-Glu-S-Bzl-L-Cys-Gly-OBzl.

HY-70057S4

Safinamide-d5

Safinamide-d₅ (FCE 26743-d₅) is deuterium labeled Safinamide. Safinamide is a potent, selective, and reversible monoamine oxidase B (MAO-B) inhibitor (IC₅₀=0.098 μM) over MAO-A (IC₅₀=580 μM) . Safinamide also blocks sodium channels and modulates glutamate (Glu) release, showing a greater affinity at depolarized (IC₅₀=8?μM) than at resting (IC₅₀=262?μM) potentials. Safinamide has neuroprotective and neurorescuing effects and can be used for the study of parkinson disease, ischemia stroke etc.al .

HY-13443S

Exendin-4 (Leu-13C6,15N) TFA
Exendin-4 (Leu- ¹³C₆, ¹⁵N) (Exenatide (Leu- ¹³C₆, ¹⁵N)) TFA is the ¹³C- and ¹⁵N-labeled Exendin-4 TFA (HY-13443). Exendin-4 (Exenatide), a 39 amino acid peptide, is a long-acting glucagon-like peptide-1 receptor agonist with an IC₅₀ of 3.22 nM .

HY-P0119S

Lixisenatide (Leu-13C6,15N) TFA

Lixisenatide (Leu- ¹³C₆, ¹⁵N) TFA is the ¹³C- and ¹⁵N-labeled Lixisenatide (HY-P0119). Lixisenatide is a glucagon-like peptide-1 (GLP-1) receptor agonist. Lixisenatide inhibits the inflammatory response through down regulation of pro-inflammatory cytokines, and suppresses of the Akt-MEK1/2 signaling pathway. Lixisenatide can inhibit oxidative stress, mitochondrial dysfunction and apoptosis. Lixisenatide can be used for the researches of inflammation, metabolic disease, neurological disease and cardiovascular disease, such as rheumatoid arthritis, diabetes, Alzheimer's disease and atherosclerosis .

HY-P4229

([D8]Val7,10)-C-Peptide (human)
([D8]Val7,10)-C-Peptide (human) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-114118S3

Semaglutide-13C6,15N TFA

Semaglutide- ¹³C₆, ¹⁵N TFA is the ¹³C- and ¹⁵N-labeled Semaglutide TFA (HY-114118A). Semaglutide TFA is a long-acting, selective, competitive GLP-1R agonist that can penetrate the blood-brain barrier. After activating GLP-1R, Semaglutide TFA promotes insulin secretion, inhibits gastric emptying and appetite, and at the same time enhances autophagy, inhibits oxidative stress and apoptosis. Semaglutide TFA also regulates mitochondrial function and lipid metabolism (such as reducing de novo lipogenesis in the liver). Semaglutide TFA has activities such as lowering blood sugar, reducing weight, neuroprotection (such as improving motor function in Parkinson's disease models, reducing α-synuclein aggregation) and improving hepatic steatosis. Semaglutide TFA can be used for the study of neurodegenerative diseases and liver diseases such as type 2 diabetes, obesity, Parkinson's disease, metabolic associated fatty liver disease (MASLD), and cancer .

HY-114118S1

Semaglutide-d8 tetraTFA

Semaglutide-d₈ tetraTFA is the deuterium labeled Semaglutide (HY-114118). Semaglutide is a long-acting, selective, competitive GLP-1R agonist that can penetrate the blood-brain barrier. After activating GLP-1R, Semaglutide promotes insulin secretion, inhibits gastric emptying and appetite, and at the same time enhances autophagy, inhibits oxidative stress and apoptosis. Semaglutide also regulates mitochondrial function and lipid metabolism (such as reducing de novo lipogenesis in the liver). Semaglutide has activities such as lowering blood sugar, reducing weight, neuroprotection (such as improving motor function in Parkinson's disease models, reducing α-synuclein aggregation) and improving hepatic steatosis. Semaglutide can be used for the study of neurodegenerative diseases and liver diseases such as type 2 diabetes, obesity, Parkinson's disease, metabolic associated fatty liver disease (MASLD), and cancer .

HY-114118S

Semaglutide-d8

Semaglutide-d₈ is the deuterium labeled Semaglutide (HY-114118). Semaglutide is a long-acting, selective, competitive GLP-1R agonist that can penetrate the blood-brain barrier. After activating GLP-1R, Semaglutide promotes insulin secretion, inhibits gastric emptying and appetite, and at the same time enhances autophagy, inhibits oxidative stress and apoptosis. Semaglutide also regulates mitochondrial function and lipid metabolism (such as reducing de novo lipogenesis in the liver). Semaglutide has activities such as lowering blood sugar, reducing weight, neuroprotection (such as improving motor function in Parkinson's disease models, reducing α-synuclein aggregation) and improving hepatic steatosis. Semaglutide can be used for the study of neurodegenerative diseases and liver diseases such as type 2 diabetes, obesity, Parkinson's disease, metabolic associated fatty liver disease (MASLD), and cancer .

HY-159191S

VQPGQN(Phe-13C9,15N)HMFTKEKLEEVIKDI TFA
VQPGQN(Phe- ¹³C9, ¹⁵N)HMFTKEKLEEVIKDI (TFA) is the ¹³C and ¹⁵N labeled isotope of VQPGQN-HMFTKEKLEEVIKDI (TFA) .

HY-158994S

MEGDSRGG-(Ala-13C3,15N)-GGEA-(Leu-13C6,15N)-DPESAASSLSGAS TFA
MEGDSRGG-(Ala- ¹³C₃, ¹⁵N)-GGEA-(Leu- ¹³C₆, ¹⁵N)-DPESAASSLSGAS TFA is a ¹³C- and ¹⁵N-labeled peptide containing ¹³C₃, ¹⁵N-labeled alanine (Ala) and ¹³C₆, ¹⁵N-labeled leucine (Leu).

HY-P0014AS

Liraglutide-d8 tetraTFA
Liraglutide-d₈ tetraTFA is deuterium labeled Liraglutide (HY-P0014). Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used for the study of type 2 diabetes mellitus .

HY-P0014S2

Liraglutide-13C6,15N TFA
Liraglutide- ¹³C₆, ¹⁵N (TFA)is the ¹³C and ¹⁵N labeledLiraglutide(HY-P0014). Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used clinically to treat type 2 diabetes mellitus .

HY-P0014S1

Liraglutide-13C5,15N TFA
Liraglutide- ¹³C₅, ¹⁵N (tetraTFA) is the ¹³C and ¹⁵N labeled Liraglutide (HY-P0014) . Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used clinically to treat type 2 diabetes mellitus .

HY-P1363S1

β-Amyloid (1-42), human, Ala(13C3,15N) TFA

β-Amyloid (1-42), human, Ala( ¹³C₃, ¹⁵N) TFA is the ¹³C and ¹⁵N-labeled β-Amyloid (1-42), human (HY-P1363A). β-Amyloid (1-42) (Amyloid β-peptide (1-42)), human, a 42-amino acid peptide that has not been treated with HFIP, is a brain-penetrant amyloid protein fragment, which can be used in research on Alzheimer's disease and Down’s syndrome. β-Amyloid (1-42), human remaining as a monomer exhibits antioxidant and neuroprotective effects. β-Amyloid (1-42), human, after being monomericized by HFIP and dissolved in DMSO to form the stock solution, on the one hand, can form soluble oligomers (AβOs) when incubated at 4 ℃, which have synaptic toxicity and neurotoxicity; on the other hand, it can be incubated at 37 ℃ to form insoluble fibrils, with lower neurotoxicity, and participating in the oxidative damage process. Aβ42 oligomers bind to various neuronal surface receptors (such as PrPc, mGluR5, NMDA receptors, etc.), triggering oxidative stress, calcium homeostasis imbalance, and synaptic toxicity via activating downstream signaling pathways, leading to neuronal dysfunction and death .

HY-163423S

TELAEPTSTR-(Arg-13C6,15N4)
TELAEPTSTR-(Arg- ¹³C₆, ¹⁵N₄) is ¹³C and ¹⁵N labeled TELAEPTSTR-(Arg).

HY-156344S1

GLEWVAEIR-(Arg-13C6,15N4) (TFA)
GLEWVAEIR-(Arg- ¹³C₆, ¹⁵N₄) (TFA) is the peptide containing ¹³C- and ¹⁵N-labeled Arg.

HY-173102S

LQEEIDAVL(Pro-13C5,15N)NK TFA
LQEEIDAVL(Pro- ¹³C₅, ¹⁵N)NK TFA is the ¹³C- and ¹⁵N-labeled LQEEIDAVL(Pro)NK TFA.

HY-176277S

Fibrinopeptide B, human-(Val-13C5,15N, Arg-13C6,15N4) TFA
Fibrinopeptide B, human-(Val- ¹³C₅, ¹⁵N, Arg- ¹³C₆, ¹⁵₄) TFA is the ¹³C- and ¹⁵N-labeled Fibrinopeptide B, human (HY-P1493). Fibrinopeptide B, human is a 14-aa peptide, released from the amino-terminus of β-chains of fibrinogen by thrombin .

HY-173105S

TPEEAHALSA(Pro-13C5,15N)TSR TFA
TPEEAHALSA(Pro- ¹³C₅, ¹⁵N)TSR TFA is the ¹³C- and ¹⁵N-labeled TPEEAHALSA(Pro)TSR TFA.

HY-163427S

FNLEALVTHTLPFEK-(Lys-13C6,15N2)
FNLEALVTHTLPFEK-(Lys- ¹³C₆, ¹⁵N₂) is ¹³C and ¹⁵N labeled FNLEALVTHTLPFEK-(Lys) .

HY-173091S

pyroE-QEAVEGGC(Cam)SHLGQSYADR-(Arg-13C6,15N4) TFA
pyroE-QEAVEGGC(Cam)SHLGQSYADR-(Arg- ¹³C₆, ¹⁵N₄) TFA is the ¹³C- and ¹⁵N-labeled pyroE-QEAVEGGC(Cam)SHLGQSYADR-(Arg) TFA.

HY-158992S

SP-(Val-13C5,15N)-EKNQ-(Leu-13C6,15N)-TIDFINIVKDPVPHNEYKT TFA
SP-(Val- ¹³C₅, ¹⁵)-EKNQ-(Leu- ¹³C₆, ¹⁵)-TIDFINIVKDPVPHNEYKT TFA is a ¹³C- and ¹⁵N-labeled peptide containing ¹³C₅, ¹⁵N-labeled valine (Val) and ¹³C₆, ¹⁵N-labeled leucine (Leu).

HY-P0265AS

β-Amyloid-15N (1-40) TFA
β-Amyloid- ¹⁵N (1-40) (TFA) is the ¹⁵N-labledβ-Amyloid (1-40) (TFA). β-Amyloid (1-40) is a primary protein in plaques found in the brains of patients with Alzheimer's disease .

HY-P1363S

β-Amyloid-15N (1-42), human TFA
β-Amyloid- ¹⁵N (1-42), human (TFA) is the ¹⁵N-labledβ-Amyloid (1-42) (TFA). β-Amyloid (1-42), human TFA (Amyloid β-Peptide (1-42) (human) TFA) is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease .

HY-173100S

GIFP(Leu-13C6,15N)AER TFA
GIFP(Leu- ¹³C₆, ¹⁵N)AER TFA is the ¹³C- and ¹⁵N-labeled GIFP(Leu)AER TFA.

HY-173101S

GHFP(Leu-13C6,15N)AER TFA
GHFP(Leu- ¹³C₆, ¹⁵N)AER TFA is the ¹³C- and ¹⁵N-labeled GHFP(Leu)AER TFA.

HY-P6421S

LGPLVEQG-Arg(13C6,15N4) TFA
LGPLVEQG-Arg( ¹³C₆, ¹⁵N₄) TFA is a peptide containing ¹³C₆ and ¹⁵N₄ labeled Arg .

HY-P6425S

LCADMEDV-Arg(13C6,15N4) TFA
LCADMEDV-Arg( ¹³C₆, ¹⁵N₄) TFA is a peptide containing ¹³C₆ and ¹⁵N₄ labeled Arg .

HY-173085S

TPPSSGEPPK-(Lys-13C6,15N2) TFA
TPPSSGEPPK-(Lys- ¹³C₆, ¹⁵N₂) TFA is the ¹³C- and ¹⁵N-labeled TPPSSGEPPK-(Lys) TFA.

HY-P6696S

β-CL, Ala(13C3,15N) TFA
β-CL, Ala(sup>13C₃, ¹⁵N) TFA is the ¹³C- and ¹⁵N-labeled β-CL TFA.

HY-P6424S

LGADMEDVCG-Arg(13C6,15N4) TFA
LGADMEDVCG-Arg( ¹³C₆, ¹⁵N₄) TFA is a peptide containing ¹³C₆ and ¹⁵N₄ labeled Arg .

HY-P5190S

RQIK-(Lys-fructosyl)-QTA-(Leu-13C6,15N)-VE
RQIK-(Lys-fructosyl)-QTA-(Leu- ¹³C₆, ¹⁵N)-VE is the ¹³C and ¹⁵N labeled compound .

HY-176179S

LFFAADHLV(Val-13C5,15N)CE
LFFAADHLV(Val- ¹³C₅, ¹⁵N)CE is the ¹³C- and ¹⁵N-labeled LFFAADHLVCE.

HY-163422S

PHSHPALTPEQK-(Lys-13C6,15N2)
PHSHPALTPEQK-(Lys- ¹³C₆, ¹⁵N₂) is ¹³C and ¹⁵N labeled PHSHPALTPEQK-(Lys).

HY-163426S

AFFGHYLYEVAR-(Arg-13C6,15N4)
AFFGHYLYEVAR-(Arg- ¹³C₆, ¹⁵N₄) is ¹³C and ¹⁵N labeled AFFGHYLYEVAR-(Arg) .

HY-P5201S1

VTSEGAGLQLQK-13C6,15N2 TFA
VTSEGAGLQLQK- ¹³C₆, ¹⁵N₂ (TFA) is the ¹³C- and ¹⁵N-labeled VTSEGAGLQLQK. VTSEGAGLQLQK is an amino acid sequence in the C-terminal region of recombinant human alpha-acid glucosidase (rhGAA), which can be used to bind anti-drug antibodies in plasma and quantitatively analyze the therapeutic effect .

HY-173087S

TPPSSGEPPKSGDR-(Arg-13C6,15N4) TFA
TPPSSGEPPKSGDR-(Arg- ¹³C₆, ¹⁵N₄) TFA is a is the ¹³C- and ¹⁵N-labeled TPPSSGEPPKSGDR-(Arg) TFA.

HY-173089S

TPSLP(pT)PP(pT)REPK-(Lys-13C6,15N2) TFA
TPSLP(pT)PP(pT)REPK-(Lys- ¹³C₆, ¹⁵N₂) TFA is the ¹³C- and ¹⁵N-labeled TPSLP(pT)PP(pT)REPK-(Lys) TFA.

HY-156343S1

SNNYATHYAESVK-(Lys-13C6,15N2) (TFA)
SNNYATHYAESVK-(Lys- ¹³C₆, ¹⁵N₂) (TFA) is the peptide containing ¹³C- and ¹⁵N-labeled Lys.

HY-176176S

MDEKMLVLWVVALS(Gly-13C2,15N)IST
MDEKMLVLWVVALS(Gly- ¹³C₂, ¹⁵N)IST is the ¹³C- and ¹⁵N-labeled MDEKMLVLWVVALSIST.

HY-163992S

VTMTRDTSISTAYMELSR-(Ile-13C6,15N)
VTMTRDTSISTAYMELSR-(Ile-13C6,15N) is the ¹³C and ¹⁵N labeled isotope of VTMTRDTSISTAYMELSR .

HY-176177S

DEKM(Leu-13C6,15N)VLWVVALSGISTLFFAA
DEKM(Leu- ¹³C₆, ¹⁵N)VLWVVALSGISTLFFAA is the ¹³C- and ¹⁵N-labeled DEKMVLWVVALSGISTLFFAA.

HY-159192S

SADDNIKTPAE(Arg-13C6,15N4)LLGPLPPSADDNLKT TFA
SADDNIKTPAE(Arg- ¹³C6, ¹⁵N4)LLGPLPPSADDNLKT (TFA) is the ¹³C and ¹⁵N labeled isotope of SADDNIKTPAE-LLGPLPPSADDNLKT (TFA) .

HY-P2625S

GLP-2(3-33) (Leu-13C6,15N)
GLP-2(3-33) (Leu- ¹³C₆, ¹⁵N) is ¹³C and ¹⁵N labeled GLP-2(3-33) (HY-P2625). GLP-2(3-33), generated naturally by dipeptidylpeptidase IV (DPPIV), acts as a partial agonist on GLP-2 receptor (EC₅₀=5.8 nM).

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