iE-DAP dihydrochloride

Cat. No.: HY-P5523A: Data Sheet Handling Instructions
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iE-DAP dihydrochloride is a Nod1 agonist. Nod1 recognition of iE-DAP dihydrochloride can activate the NF-κB pathway, leading to an inflammatory cytokine response. iE-DAP dihydrochloride can be used for the research of maternal-fetal inflammation and preterm labor.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

iE-DAP dihydrochloride Chemical Structure

Size	Stock	Quantity
1 mg	In-stock	Estimated Time of Arrival: December 31
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

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This product is a controlled substance and not for sale in your territory.

Other Forms of iE-DAP dihydrochloride:

iE-DAP Get quote

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•Related Screening Libraries:

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View All NOD-like Receptor (NLR) Isoform Specific Products:

View All Isoforms

NLRP3 NLRP1 NOD1 NOD2

Biological Activity
Purity & Documentation
References
Customer Review

Description

Molecular Weight

392.23

Formula

C₁₂H₂₃Cl₂N₃O₇

Appearance

Solid

Sequence

γ-d-Glu-meso-DAP

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (254.95 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.5495 mL	12.7476 mL	25.4952 mL
5 mM	0.5099 mL	2.5495 mL	5.0990 mL
10 mM	0.2550 mL	1.2748 mL	2.5495 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Cardenas I, et al. Nod1 activation by bacterial iE-DAP induces maternal-fetal inflammation and preterm labor. J Immunol. 2011 Jul 15;187(2):980-6. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.5495 mL	12.7476 mL	25.4952 mL	63.7381 mL
	5 mM	0.5099 mL	2.5495 mL	5.0990 mL	12.7476 mL
	10 mM	0.2550 mL	1.2748 mL	2.5495 mL	6.3738 mL
	15 mM	0.1700 mL	0.8498 mL	1.6997 mL	4.2492 mL
	20 mM	0.1275 mL	0.6374 mL	1.2748 mL	3.1869 mL
	25 mM	0.1020 mL	0.5099 mL	1.0198 mL	2.5495 mL
	30 mM	0.0850 mL	0.4249 mL	0.8498 mL	2.1246 mL
	40 mM	0.0637 mL	0.3187 mL	0.6374 mL	1.5935 mL
	50 mM	0.0510 mL	0.2550 mL	0.5099 mL	1.2748 mL
	60 mM	0.0425 mL	0.2125 mL	0.4249 mL	1.0623 mL
	80 mM	0.0319 mL	0.1593 mL	0.3187 mL	0.7967 mL
	100 mM	0.0255 mL	0.1275 mL	0.2550 mL	0.6374 mL