1. Immunology/Inflammation
  2. NOD-like Receptor (NLR)
  3. C12-iE-DAP hydrochloride

C12-iE-DAP hydrochloride  (Synonyms: Lauroyl-γ-D-glutamyl-meso-diaminopimelic acid hydrochloride; γ-D-glutamyl-meso-diaminopimelic acid hydrochloride)

Cat. No.: HY-P5524A
Handling Instructions Technical Support

C12-iE-DAP hydrochloride is the hydrochloride salt form of C12-iE-DAP (HY-P5524). C12-iE-DAP hydrochloride is a biologically active peptide that has agonistic effects on NOD1.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

C12-iE-DAP hydrochloride Chemical Structure

C12-iE-DAP hydrochloride Chemical Structure

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Based on 1 publication(s) in Google Scholar

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Description

C12-iE-DAP hydrochloride is the hydrochloride salt form of C12-iE-DAP (HY-P5524). C12-iE-DAP hydrochloride is a biologically active peptide that has agonistic effects on NOD1[1].

Molecular Weight

538.07

Synonyms

Lauroyl-γ-D-glutamyl-meso-diaminopimelic acid hydrochloride; γ-D-glutamyl-meso-diaminopimelic acid hydrochloride

Formula

C24H44ClN3O8

Appearance

Solid

Sequence

Lauroyl-γ-d-Glu-meso-diaminopimelic acid

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (185.85 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8585 mL 9.2925 mL 18.5849 mL
5 mM 0.3717 mL 1.8585 mL 3.7170 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.8585 mL 9.2925 mL 18.5849 mL 46.4624 mL
5 mM 0.3717 mL 1.8585 mL 3.7170 mL 9.2925 mL
10 mM 0.1858 mL 0.9292 mL 1.8585 mL 4.6462 mL
15 mM 0.1239 mL 0.6195 mL 1.2390 mL 3.0975 mL
20 mM 0.0929 mL 0.4646 mL 0.9292 mL 2.3231 mL
25 mM 0.0743 mL 0.3717 mL 0.7434 mL 1.8585 mL
30 mM 0.0619 mL 0.3097 mL 0.6195 mL 1.5487 mL
40 mM 0.0465 mL 0.2323 mL 0.4646 mL 1.1616 mL
50 mM 0.0372 mL 0.1858 mL 0.3717 mL 0.9292 mL
60 mM 0.0310 mL 0.1549 mL 0.3097 mL 0.7744 mL
80 mM 0.0232 mL 0.1162 mL 0.2323 mL 0.5808 mL
100 mM 0.0186 mL 0.0929 mL 0.1858 mL 0.4646 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
C12-iE-DAP hydrochloride
Cat. No.:
HY-P5524A
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