2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Aspartylglutamate

Aspartylglutamate  (Synonyms: Asp-Glu)

Cat. No.: HY-136980 Purity: 99.79%
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Aspartylglutamate (Asp-Glu) is a dipeptide that exhibits excitatory activity, as it has been shown to depolarize CA1 pyramidal neurons and increase conductance in response to stimulation. Aspartylglutamate selectively binds to certain glutamate receptors and demonstrates potent effects in specific regions of the hippocampus, particularly in the stratum radiatum where it enhances excitatory neurotransmission.

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Aspartylglutamate Chemical Structure

Aspartylglutamate Chemical Structure

CAS No. : 6157-06-8

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Aspartylglutamate Related Antibodies

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Description

Aspartylglutamate (Asp-Glu) is a dipeptide that exhibits excitatory activity, as it has been shown to depolarize CA1 pyramidal neurons and increase conductance in response to stimulation. Aspartylglutamate selectively binds to certain glutamate receptors and demonstrates potent effects in specific regions of the hippocampus, particularly in the stratum radiatum where it enhances excitatory neurotransmission.

Molecular Weight

262.22

Formula

C9H14N2O7
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OC(C[C@H](N)C(N[C@H](C(O)=O)CCC(O)=O)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 12 mg/mL (45.76 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.8136 mL 19.0680 mL 38.1359 mL
5 mM 0.7627 mL 3.8136 mL 7.6272 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

V1

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Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.8136 mL 19.0680 mL 38.1359 mL 95.3398 mL
5 mM 0.7627 mL 3.8136 mL 7.6272 mL 19.0680 mL
10 mM 0.3814 mL 1.9068 mL 3.8136 mL 9.5340 mL
15 mM 0.2542 mL 1.2712 mL 2.5424 mL 6.3560 mL
20 mM 0.1907 mL 0.9534 mL 1.9068 mL 4.7670 mL
25 mM 0.1525 mL 0.7627 mL 1.5254 mL 3.8136 mL
30 mM 0.1271 mL 0.6356 mL 1.2712 mL 3.1780 mL
40 mM 0.0953 mL 0.4767 mL 0.9534 mL 2.3835 mL
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Aspartylglutamate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Aspartylglutamate6157-06-8Asp-GluEndogenous MetaboliteInhibitorinhibitorinhibit

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