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Lovastatin-d<sub>3</sub> hydroxy acid

" in MedChemExpress (MCE) Product Catalog:

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Click Chemistry:	Labeling and Fluorescence Imaging (6) DBCO (1) PROTAC Synthesis (1) Azide (41) Alkynes (59)
Oligonucleotides:	A (3) C (5) G (7) Flavoring Agents (1) I (1) Phospholipids (16) siRNA drugs (10) Antisense Oligonucleotides (1) siRNAs (13) Pegylated Lipids (3) U (6) Liposomal Film-forming Agents (1) Disintegrants (1) Mouse Pre-designed siRNA Sets (1) Cationic Lipids (8) Human Pre-designed siRNA Sets (1) Polymers (4) Nucleosides and their Analogs (22) Thickeners (1) Nucleoside Phosphoramidites (3) Rat Pre-designed siRNA Sets (1) Suspending Agents (1) Solubilizing Agents (1) Freeze-drying Protective Agents (1) Cholesterol (2) Nucleotides and their Analogs (8) Emulsifiers (2) Sweetening Agents (1)

8292

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

367

Biochemical Assay Reagents

1611

Peptides

Inhibitory Antibodies

836

Natural
Products

Recombinant Proteins

3945

Isotope-Labeled Compounds

Antibodies

102

Click Chemistry

Oligonucleotides

Targets Recommended: Amino acid Transporter Amino Acid Derivatives Amino Acid Decarboxylase Hydroxycarboxylic Acid Receptor (HCAR) Amino Acid Oxidase Free Fatty Acid Receptor Fatty Acid Synthase (FASN) P-glycoprotein Apical Sodium-Dependent Bile Acid Transporter G protein-coupled Bile Acid Receptor 1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W008216S

HMMNI-d3 hydroxy Dimetridazole-d<sub>3sub>	Drug Metabolite Isotope-Labeled Compounds Parasite	Infection
HMMNI-d₃ (Hydroxy Dimetridazole-d₃) is deuterium labeled HMMNI (HY-W008216). HMMNI (Hydroxy dimetridazole) is a hydroxy metabolite of Dimetridazol (HY-B1244). Dimetridazole is a nitroimidazole class agent that combats protozoan infections .

HY-N0504S2

Lovastatin-d3 Mevinolin-d<sub>3sub>	Isotope-Labeled Compounds HMG-CoA Reductase (HMGCR) Autophagy Ferroptosis	Cardiovascular Disease Cancer
Lovastatin-d₃ is deuterium labeled Lovastatin. Lovastatin is a cell-permeable HMG-CoA reductase inhibitor used to lower cholesterol.

HY-123672S

Lovastatin-d3 hydroxy acid sodium	Isotope-Labeled Compounds HMG-CoA Reductase (HMGCR)	Metabolic Disease
Lovastatin-d₃ hydroxy acid (sodium) is the deuterium labeled Lovastatin hydroxy acid sodium. Lovastatin hydroxy acid sodium (Mevinolinic acid sodium) is a highly potent inhibitor of HMG-CoA reductase with a K_i of 0.6 nM .

HY-N0504S1

Lovastatin-d9	Isotope-Labeled Compounds HMG-CoA Reductase (HMGCR) Autophagy Ferroptosis	Cardiovascular Disease Cancer
Lovastatin-d₉ is the deuterium labeled Lovastatin. Lovastatin is a cell-permeable HMG-CoA reductase inhibitor used to lower cholesterol.

HY-G0003S1

*Iloperidone metabolite Hydroxy* Iloperidone-d3** P88-d<sub>3sub>; hydroxy Iloperidone-d<sub>3sub>	Drug Metabolite	Others
Iloperidone metabolite Hydroxy Iloperidone-d₃ is the deuterium labeled Iloperidone metabolite Hydroxy Iloperidone .

HY-RS13999

SUB1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SUB1 Human Pre-designed siRNA Set A contains three designed siRNAs for SUB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SUB1 Human Pre-designed siRNA Set A SUB1 Human Pre-designed siRNA Set A

HY-RS18793

Sub1 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Sub1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Sub1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Sub1 Mouse Pre-designed siRNA Set A Sub1 Mouse Pre-designed siRNA Set A

HY-RS25282

Sub1 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Sub1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Sub1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Sub1 Rat Pre-designed siRNA Set A Sub1 Rat Pre-designed siRNA Set A

HY-146227

DNA topoisomerase II inhibitor 1	Topoisomerase Apoptosis	Cancer
DNA topoisomerase II inhibitor 1 (compound 8ed) is a potent DNA topoisomerase II inhibitor. DNA topoisomerase II inhibitor 1 shows anti-proliferative activity. DNA topoisomerase II inhibitor 1 induces apoptosis and cell cycle arrest at sub G1 phase .

HY-108263S

*3-Hydroxy* Midostaurin-d5** CGP52421-d<sub>5sub>	Isotope-Labeled Compounds FLT3	Cancer
3-Hydroxy Midostaurin-d₅ is a deuterium labeled 3-Hydroxy Midostaurin. 3-Hydroxy Midostaurin is a metabolite of PKC412, which effectively inhibits FMS-like tyrosine kinase-3 (FLT3) autophosphorylation with IC₅₀s of approximately 132 nM and 9.8 μM in culture medium and plasma, respectively .

HY-169892S

*4-Hydroxy* Nonenal Glutathione-d3** 4-HNE-GSH-d<sub>3sub>	Isotope-Labeled Compounds	Others
4-Hydroxy Nonenal Glutathione-d₃ (4-HNE-GSH-d₃) is deuterium labeled 4-Hydroxy Nonenal Glutathione .

HY-W354610S

*N-(4-Hydroxy-3-methoxybenzyl)stearamide-d3* N-Vanillyloctadecanamide-d<sub>3sub>	Isotope-Labeled Compounds	Others
N-(4-Hydroxy-3-methoxybenzyl)stearamide-d₃ is the deuterium labeled N-(4-hydroxy-3-methoxybenzyl)stearamide .

HY-139429S

*(−)-11-Hydroxy-Δ8-THC-d3* (−)-11-Hydoxy-Δ8-Tetahydocaabiol-d<sub>3sub>; (−)-tas-Δ8-THC-d<sub>3sub>; 7-hydoxy-Δ6-THC-d<sub>3sub>	Isotope-Labeled Compounds	Others
(?)-11-Hydroxy-Δ8-THC-d₃ ((?)-11-Hydoxy-Δ8-Tetahydocaabiol-d₃) is deuterium labeled (?)-11-hydroxy-Δ8-THC .

HY-W012927S

*4-Hydroxy-5-methylfuran-3(2H)-one-d3* Chicory furaneol-d<sub>3sub>	Isotope-Labeled Compounds	Others
4-Hydroxy-5-methylfuran-3(2H)-one-d₃ is deuterated labeled 4-Hydroxy-5-methylfuran-3(2H)-one (HY-W012927). 4-Hydroxy-5-methylfuran-3(2H)-one (Chicory furaneol) can be used to assay oxidoreductase activity. 4-Hydroxy-5-methylfuran-3(2H)-one is a kind of biological materials or organic compounds that are widely used in life science research .

HY-W021008S

*3-Hydroxy-4,5-dimethylfuran-2(5H)-one-d2* Dimethylhydroxyfuranone-d<sub>2sub>	Isotope-Labeled Compounds	Others
3-Hydroxy-4,5-dimethylfuran-2(5H)-one-d₂ is deuterated labeled 3-Hydroxy-4,5-dimethylfuran-2(5H)-one.

HY-126121S

*2-Hydroxy* Ibuprofen-d6** (±)-2-hydroxy Ibuprofen-d<sub>6sub>	Isotope-Labeled Compounds COX	Inflammation/Immunology Cancer
2-Hydroxy Ibuprofen-d₆ is the deuterium labeled 2-Hydroxy Ibuprofen. 2-Hydroxy Ibuprofen is a metabolite of Ibuprofen. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC₅₀s of 13 μM and 370 μM, respectively .

HY-10844S1

Pretomanid-d5 PA-824-d<sub>5sub>; (S)-PA 824-d<sub>5sub>	Antibiotic Bacterial Isotope-Labeled Compounds	Infection Cancer
Pretomanid-d₅ is deuterated labeled Pretomanid (HY-10844). Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 μg/mL.

HY-P10215

Ac-{Cpg}-Thr-Ala-{Ala(CO)}-Asp-{Cpg}-NH2	Parasite	Infection
Ac-{Cpg}-Thr-Ala-{Ala(CO)}-Asp-{Cpg}-NH2 (compound 40) is a potent **Plasmodium subtilisin-like protease 1 (SUB1)** inhibitor. SUB1-IN-1 shows IC₅₀ values of 12 nM and 10 nM against P. vivax and P. falciparum SUB1 (Pv- and PfSUB1), respectively .

HY-12773AS2

*5-Hydroxy* Propafenone-d6 hydrochloride** GPV-129-d<sub>6sub> hydrochloride	Isotope-Labeled Compounds	Others
5-Hydroxy Propafenone-d₆ hydrochloride is deuterated labeled 5-Hydroxy Propafenone.

HY-12772S

Hydroxy Itraconazole-d8 R-63373-d<sub>8sub>	Fungal	Others
Hydroxy Itraconazole-d₈ is the deuterium labeled Hydroxy Itraconazole. Hydroxy Itraconazole is an active metabolite of Itraconazole (ITZ), which is a triazole antifungal agent.

HY-12772S3

Hydroxy Itraconazole-d6 R-63373-d<sub>6sub>	Isotope-Labeled Compounds Fungal	Others
Hydroxy Itraconazole-d₆ (R-63373-d₆) is deuterium labeled Hydroxy Itraconazole. Hydroxy Itraconazole (Itraconazole metabolite Hydroxy Itraconazole; R-63373) is an active metabolite of Itraconazole (ITZ), which is a triazole antifungal agent.

HY-131543S

*22-Hydroxy* Mifepristone-d6** RU 42698-d<sub>6sub>	Isotope-Labeled Compounds	Others
22-Hydroxy Mifepristone-d₆ is the deuterium labeled 22-Hydroxy Mifepristone (HY-131543). 22-Hydroxy Mifepristone (RU 42698) is an orally active hydroxylated alcoholic metabolite with antiprogestational and antiglucocorticoidal activities, which contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. The relative binding affinity of 22-Hydroxy Mifepristone to the human glucocorticoid receptor is 48% .

HY-W025101S

*Ethyl 3-hydroxy-3-methylbutanoate-d6* Ethyl 3-hydroxy-3-methylbutyrate-d<sub>6sub>	Isotope-Labeled Compounds	Others
Ethyl 3-hydroxy-3-methylbutanoate-d₆ is the deuterium labeled Ethyl 3-hydroxy-3-methylbutanoate .

HY-151930S1

*8′-Hydroxy* ABA-d2** 8'-OH-ABA-d<sub>2sub>	Drug Metabolite	Others
8′-Hydroxy ABA-d₂ is the deuterium labeled 8’-Hydroxy ABA .

HY-111975S5

*7'-Hydroxy* ABA-d7** 7'-OH ABA-d<sub>7sub>	Isotope-Labeled Compounds	Others
7'-Hydroxy ABA-d₇ is the deuterium labeled 7'-Hydroxy ABA .

HY-151930S

*8′-Hydroxy* ABA-d8** 8'-OH-ABA-d<sub>8sub>	Drug Metabolite	Others
8′-Hydroxy ABA-d₈ is the deuterium labeled 8’-Hydroxy ABA .

HY-111975S1

*7'-Hydroxy* ABA-d2** 7'-OH ABA-d<sub>2sub>	Isotope-Labeled Compounds	Others
7'-Hydroxy ABA-d₂2 is the deuterium labeled 7'-Hydroxy ABA .

HY-115354S

*4-Hydroxy* Alprazolam-d5** 4-hydroxyalprazolam-d<sub>5sub>; RS-4-hydroxyalprazolam-d<sub>5sub>	Isotope-Labeled Compounds	Others
4-Hydroxy Alprazolam-d5 (4-Hydroxyalprazolam-d5; RS-4-Hydroxyalprazolam-d5) is the deuterium labeled 4-hydroxy Alprazolam (HY-115354) .

HY-W008216

HMMNI hydroxy Dimetridazole	Drug Metabolite Parasite	Infection
HMMNI (Hydroxy dimetridazole) is a hydroxy metabolite of Dimetridazole (HY-B1244). Dimetridazole is a nitroimidazole class drug that combats protozoan infections .

HY-U00050S

(E)-10-Hydroxynortriptyline-d3 E-10-OH-NT-d<sub>3sub>	Isotope-Labeled Compounds Drug Metabolite	Neurological Disease
(E)-10-Hydroxynortriptyline-d₃ is a deuterium labeled (E)-10-Hydroxy Nortriptyline. (E)-10-Hydroxy Nortriptyline is a metabolite of Nortriptyline. Nortriptyline is a tricyclic antidepressant and the main active metabolite of Amitriptyline, and is used to relieve the symptoms of depression .

HY-B1189S

Meglutol-d3 Dicrotalic acid-d<sub>3sub>; 3-hydroxy-3-methylglutaric acid-d<sub>3sub>	Autophagy HMG-CoA Reductase (HMGCR) Endogenous Metabolite	Cardiovascular Disease
Meglutol-d₃ is the deuterium labeled Meglutol . Meglutol is an antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids, and inhibits the activity of hydroxymethylglutarryl CoA reductases, which is the rate limiting enzyme in the biosynthesis of cholesterol.

HY-121385S1

Hydroxy Bosentan-d4 Ro 48-5033-d<sub>4sub>	Isotope-Labeled Compounds Endogenous Metabolite	Cardiovascular Disease
Hydroxy Bosentan-d₄ is deuterium labeled Hydroxy bosentan. Hydroxy bosentan (Ro 48-5033) is a primary metabolite of Bosentan (BOS) metabolized by the cytochrome P450 system in the liver. Ro 48-5033 assists BOS pharmacologically, retaining 10%-20% activities .

HY-121385S

Hydroxy Bosentan-d6 Ro 48-5033-d<sub>6sub>	Isotope-Labeled Compounds Endogenous Metabolite	Cardiovascular Disease
Hydroxy Bosentan-d₆ is deuterium labeled Hydroxy bosentan. Hydroxy bosentan (Ro 48-5033) is a primary metabolite of Bosentan (BOS) metabolized by the cytochrome P450 system in the liver. Ro 48-5033 assists BOS pharmacologically, retaining 10%-20% activities .

HY-B1159S1

Nitroxoline-d5 8-hydroxy-5-nitroquinoline-d<sub>5sub>; 5-Nitro-8-quinolinol-d<sub>5sub>	Isotope-Labeled Compounds Antibiotic Bacterial Apoptosis Autophagy	Infection Cancer
Nitroxoline-d₅ (8-Hydroxy-5-nitroquinoline-d₅) is deuterium labeled Nitroxoline. Nitroxoline (8-Hydroxy-5-nitroquinoline), an antibiotic, is an orally active antibiofilm agent. Nitroxoline reduces the formation and induces the dispersal of Pseudomonas aeruginosa biofilms by chelation of iron and zinc. Nitroxoline can be used for the urinary tract infections and cancer research ^[3].

HY-W008216R

HMMNI (Standard) hydroxy Dimetridazole (Standard)	Drug Metabolite Parasite	Infection
HMMNI (Standard) (Hydroxy Dimetridazole (Standard)) is the analytical standard of HMMNI (HY-W008216). This product is intended for research and analytical applications. HMMNI (Hydroxy dimetridazole) is a hydroxy metabolite of Dimetridazol (HY-B1244). Dimetridazole is a nitroimidazole class drug that combats protozoan infections .

HY-12773AS

*5-Hydroxy* Propafenone-d5 hydrochloride** GPV-129 D5 Hydrochloride; Lu 40-545 d<sub>5sub>	Isotope-Labeled Compounds	Cardiovascular Disease
5-Hydroxy Propafenone-d₅ (hydrochloride) is the deuterium labeled 5-Hydroxy Propafenone.

HY-118714S

*α-Hydroxy* alprazolam-d5** U 40125-d<sub>5sub>; alpha-hydroxyalprazolam-d<sub>5sub>	Isotope-Labeled Compounds	Others
α-Hydroxy alprazolam-d₅ (U 40125-d₅; alpha-Hydroxyalprazolam-d₅) is the deuterium labled α-hydroxy alprazolam (HY-118714).

HY-17461S3

Cortisone-d2 17-hydroxy-11-dehydrocorticosterone-d<sub>2sub>; Kendall's compound E-d<sub>2sub>	Isotope-Labeled Compounds Glucocorticoid Receptor Endogenous Metabolite	Endocrinology
Cortisone-d₂ is the deuterium labeled Cortisone. Cortisone (17-Hydroxy-11-dehydrocorticosterone), an oxidized metabolite of Cortisol (a Glucocorticoid). Cortisone acts as an immunosuppressant and anti-inflammatory agent. Cortisone can partially intervene in binding of Glucocorticoid to Glucocorticoid-receptor at high concentrations ^[3] .

HY-124352S

*2-Nonyl-3-hydroxy-4-quinolone-d4* C9-PQS-d<sub>4sub>	Isotope-Labeled Compounds Bacterial	Others
2-Nonyl-3-hydroxy-4-quinolone-d₄ (C9-PQS-d₄) is deuterium labeled 2-Nonyl-3-hydroxy-4-quinolone. 2-nonyl-3-hydroxy-4-Quinolone (C9-PQS) is a quinolone compound produced by P. aeruginosa and other related bacterias. 2-nonyl-3-hydroxy-4-Quinolone is a quorum sensing (QS) signal molecule that controls the expression of many virulence genes as a function of cell population density .

HY-B0648S

Medroxyprogesterone-d3 17α-hydroxy-6α-methylprogesterone-d<sub>3sub>; U8840-d<sub>3sub>	Progesterone Receptor	Endocrinology
Medroxyprogesterone-d₃ is the deuterium labeled Medroxyprogesterone. Medroxyprogesterone is a progestin, a synthetic variant of the human hormone progesterone and a potent progesterone receptor agonist.

HY-130319

9(S)-HEPE	Drug Metabolite	Metabolic Disease
9(S)-HEPE, a hydroxy fatty acid, is a metabolite of Eicosapentaenoic acid .

HY-32351AS

Calcifediol-d6 monohydrate 25-hydroxy Vitamin D3-d<sub>6sub> monohydrate	Isotope-Labeled Compounds VD/VDR Endogenous Metabolite	Metabolic Disease
Calcifediol-d₆ monohydrate is the deuterium labeled Calcifediol monohydrate. Calcifediol monohydrate (25-hydroxy Vitamin D3 monohydrate), is an effective VDR ligand and VD supplement. Calcifediol is a prohormone of the vitamin D endocrine system (VDES) and is hydroxylated in the liver to produce the active form, calcitriol. Calcifediol can rapidly increase serum VD levels ^[3].

HY-B1689AS

Methantheline-d3 bromide MTB 51-d<sub>3sub>; Mantheline-d<sub>3sub>; Metantyl-d<sub>3sub>; Metanyl-d<sub>3sub>; Metaxan-d<sub>3sub>; Methanide-d<sub>3sub>	Isotope-Labeled Compounds	Others
Methantheline-d₃ (bromide) is the deuterium labeled Methantheline bromide .

HY-W700392

IMPDH-IN-2	IMPDH	Cancer
IMPDH-IN-2 (compound 2) is an inhibitor of inosine monophosphate dehydrogenase (IMPDH) with *IC_{50 for IMPDH I and IMPDH II >}*Values are 0.15 and 0.17 μM, respectively. IMPDH-IN-2 has antitumor activity .

HY-I0637S

Isovanillin-d3 3-hydroxy-4-methoxybenzaldehyde-d<sub>3sub>	Isotope-Labeled Compounds	Metabolic Disease
Isovanillin-d₃ is the deuterium labeled Isovanillin . Isovanillin is an aldehyde oxidase inhibitor . Antispasmodic activities ^[3]. Antidiarrheal activities .

HY-165678S

*(±)-10-Hydroxy-12(Z)-Octadecenoic acid-d5* 10-Hydoxy-cis-12-Octadeceoic acid-d<sub>5sub>	Isotope-Labeled Compounds	Others
(±)-10-Hydroxy-12(Z)-Octadecenoic acid-d₅ (10-Hydoxy-cis-12-Octadeceoic Acid-d₅) is deuterium labeled (±)-10-Hydroxy-12(Z)-Octadecenoic acid .

HY-113323S

3-Methoxy-4-hydroxyphenylglycol-d3 HMPG-d<sub>3sub>; MHPG-d<sub>3sub>; MOPEG-d<sub>3sub>	Endogenous Metabolite	Others
3-Methoxy-4-hydroxyphenylglycol-d₃ is the deuterium labeled 3-Methoxy-4-hydroxyphenylglycol.

HY-125833

Alpha-Naphthoflavone 5+ Cited Publications	Cytochrome P450 Aryl Hydrocarbon Receptor Apoptosis	Cancer
Alpha-Naphthoflavone is an orally active flavonoid that is a potent, competitive inhibitor of aromatase< b>aromatase. < b > IC < sub > 50 < / sub > < / b > and < b > K < sub > I < / sub > < / b > value were 0.5 and 0.2 microns. Alpha-Naphthoflavone can inhibit cell proliferation and induce apoptosis ^[3] .

HY-B1773AS5

Sodium Propionate-d3 Mycoban-d<sub>3sub>; Napropion-d<sub>3sub>; Ocuseptine-d<sub>3sub>	Isotope-Labeled Compounds	Others
Sodium Propionate-d₃ is the deuterium labeled Sodium Propionate .

HY-17413S

Zidovudine-d3 Azidothymidine-d<sub>3sub>; AZT-d<sub>3sub>; ZDV-d<sub>3sub>	Isotope-Labeled Compounds HIV	Infection Cancer
Zidovudine-d₃ is the deuterium labeled Zidovudine. Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-125833

Alpha-Naphthoflavone 5+ Cited Publications	Flavonoids Flavones Source classification Indigofera heterantha Wall. ex Brand. Plants Compositae Disease Research Fields Cancer	Cytochrome P450 Aryl Hydrocarbon Receptor Apoptosis
Alpha-Naphthoflavone is an orally active flavonoid that is a potent, competitive inhibitor of aromatase< b>aromatase. < b > IC < sub > 50 < / sub > < / b > and < b > K < sub > I < / sub > < / b > value were 0.5 and 0.2 microns. Alpha-Naphthoflavone can inhibit cell proliferation and induce apoptosis ^[3] .

HY-116688

*2-Hydroxy-4-(methylthio)butyric acid*	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Bacterial
2-Hydroxy-4-(methylthio)butyric acid is a dietary essential amino acid which is converted to Methionine (HY-13694) by 2-hydroxy acid dehydrogenase and 2-hydroxy acid oxidase. 2-Hydroxy-4-(methylthio)butyric acid is promising for research of gut disease .

HY-142105

2-Ethyl-2-hydroxybutanoic acid 2-Ethyl-2-hydroxybutyric acid	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
2-Ethyl-2-hydroxybutanoic acid (2-Ethyl-2-hydroxybutyric acid) is a hydroxy fatty acid. 2-Ethyl-2-hydroxybutanoic is a metabolite of DEHP (HY-B1945) .

HY-N3287

*Methyl 3-hydroxy-4,5-dimethoxybenzoate*	Infection Monophenols Classification of Application Fields Source classification Phenols Euphorbiaceae Plants Disease Research Fields Macaranga sinensis (Baill.) Muell. Arg.	Bacterial
Methyl 3-hydroxy-4,5-dimethoxybenzoate is a gallic acid derivant isolated from myricaria Laxiflora. Methyl 3-hydroxy-4,5-dimethoxybenzoate shows obvious antimicrobial activities. Methyl 3-hydroxy-4,5-dimethoxybenzoate shows fairly active for oxidation resistance in the presence of H₂O₂ .

HY-B0504S

Creatinine-d3 4 Publications Verification NSC13123-d<sub>3sub>	Classification of Application Fields Metabolic Disease Disease Research Fields	Isotope-Labeled Compounds Endogenous Metabolite
Creatinine-d₃ is a deuterium labeled Creatinine. Creatinine is a break-down product of creatine phosphate in muscle .

HY-W011474

Geranylgeraniol	Structural Classification Natural Products Microorganisms	NF-κB
Geranylgeraniol is an orally acitve vitamin K₂ sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model ^[3] .

HY-117586

9-PAHPA	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite
9-PAHPA is a fatty acid esters of hydroxy fatty acid (FAHFA). FAHFAs are a new family of endogenous lipids, have antidiabetic and anti-inflammatory effects .

HY-116688R

*2-Hydroxy-4-(methylthio)butyric acid (Standard)*	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Others
2-Hydroxy-4-(methylthio)butyric acid (Standard) is the analytical standard of 2-Hydroxy-4-(methylthio)butyric acid. This product is intended for research and analytical applications. 2-Hydroxy-4-(methylthio)butyric acid is a dietary essential amino acid which is converted to Methionine (HY-13694) by 2-hydroxy acid dehydrogenase and 2-hydroxy acid oxidase. 2-Hydroxy-4-(methylthio)butyric acid is promising for research of gut disease .

HY-125833R

Alpha-Naphthoflavone (Standard)	Flavonoids Flavones Source classification Indigofera heterantha Wall. ex Brand. Plants Compositae	Cytochrome P450 Aryl Hydrocarbon Receptor Apoptosis
Alpha-Naphthoflavone (Standard) is the analytical standard of Alpha-Naphthoflavone. This product is intended for research and analytical applications. Alpha-Naphthoflavone is an orally active flavonoid that is a potent, competitive inhibitor of aromatase< b>aromatase. < b > IC < sub > 50 < / sub > < / b > and < b > K < sub > I < / sub > < / b > value were 0.5 and 0.2 microns. Alpha-Naphthoflavone can inhibit cell proliferation and induce apoptosis ^[3] .

HY-N11799

Neochilenin 3-O-Methylquercetin 4′-O-glucoside	Structural Classification Flavonoids Source classification Plants Compositae Other Flavonoids	Others
Neochilenin (3-O-Methylquercetin 4 '-O-glucoside) is a glycoside of 3-O-methylquercetin, which can be isolated from the sub-family Cereoideae (Cactaceae). .

HY-105055

Didemnin B	Structural Classification Natural Products Animals Classification of Application Fields Marine natural products Source classification Other marine organisms Disease Research Fields Cancer	Others
Didemnin B is a depsipeptide extracted from the marine tunicate Trididemnin cyanophorum. Didemnin B can be used for the research of cancer .

HY-N0761A

trans-Isoferulic acid trans-3-hydroxy-4-methoxycinnamic acid	Ketones, Aldehydes, Acids Source classification Ranunculaceae Plants	NO Synthase Prostaglandin Receptor
trans-Isoferulic acid (trans-3-Hydroxy-4-methoxycinnamic acid) is an aromatic acid isolated from the roots of Clematis florida var. plena. trans-Isoferulic acid exhibits anti-inflammatory activity .trans-isoferulic acid suppresses NO and PGE2 production through the induction of Nrf2-dependent heme oxygenase-1 (HO-1) .

HY-N9012

*2-Hydroxy-5-(2-hydroxy-4-methoxybenzyl)-4-methoxybenzaldehyde*	Structural Classification Source classification Phenols Dalbergia congesta Graham ex Wight & Arn. Plants Fabaceae	Others
2-Hydroxy-5-(2-hydroxy-4-methoxybenzyl)-4-methoxybenzaldehyde is a Phenols product that can be isolated from the roots of Dalbergia congesta .

HY-N15356

9-Oxooctadecanedioic acid	Structural Classification Ketones, Aldehydes, Acids Source classification Plants Quercus suber L. Fagaceae	Bacterial
9-Oxooctadecanedioic acid is an α,ω-dicarboxylic fatty acid monomer found in the cork suberin of Quercus suber. It contributes to the formation of the hydrophobic barrier structure in plant cell walls and may play an important role in functions such as water resistance and protection against microbial penetration .

HY-N9241

*3-Hydroxy-7-methoxyflavone*	Structural Classification Flavonols Flavonoids Labiatae Source classification Gymnaster koraiensis Plants	Others
3-Hydroxy-7-methoxyflavone (compound 1) is a flavonoid. 3-Hydroxy-7-methoxyflavone is isolated from natural Salvia elegans. 3-Hydroxy-7-methoxyflavone has anti-anxiety effect .

HY-113259

*7α-Hydroxy-4-cholesten-3-one*	Structural Classification Microorganisms Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite
7α-Hydroxy-4-cholesten-3-one is an intermediate in synthesis of bile acids from cholesterol. 7α-Hydroxy-4-cholesten-3-one is a pregnane X receptor (PXR) agonist. 7α-Hydroxy-cholest-4-en-3-one is a biomarker for bile acid loss, irritable bowel syndrome, and other diseases associated with defective bile acid biosynthesis. 7α-Hydroxy-cholest-4-en-3-one is the physiological substrate for CYP8B1 .

HY-N9224

*5-Acetyl-6-hydroxy-2-(1-hydroxy-1-methylethyl)benzofuran*	Structural Classification Monophenols Source classification Artemisia dracunculus L. Phenols Plants Compositae	Others
5-Acetyl-6-hydroxy-2-(1-hydroxy-1-methylethyl)benzofuran is a Phenols product that can be isolated from the herbs of Artemisia dracunculus. .

HY-N14387

*5-Hydroxy-9-methylstreptimidone*	Structural Classification Natural Products Microorganisms Source classification	Antibiotic Bacterial Herbicide
5-Hydroxy-9-methylstreptimidone is a glutarimide antibiotic. 5-Hydroxy-9-methylstreptimidone has a weak weeding effect .

HY-N2674

*5-Hydroxy-1-methoxyxanthone* 5-hydroxy-1-methoxyxanthen-9-one	Structural Classification Flavonoids Hypericum brasiliense Choisy Source classification Hypericaceae Plants Other Flavonoids	Others
5-Hydroxy-1-methoxyxanthone (5-Hydroxy-1-methoxyxanthen-9-one) is a Iridoids product that can be isolated from the roots of Lamiophlomis rotata (Benth.) Kudo .

HY-135212R

Hydroxy ipronidazole (Standard)	Structural Classification Natural Products Source classification Endogenous metabolite	Endogenous Metabolite
Hydroxy ipronidazole (Standard) is the analytical standard of Hydroxy ipronidazole. This product is intended for research and analytical applications. Hydroxy ipronidazole (Ipronidazole-OH) is a metabolite of nitroimidazole antibiotics, such as ipronidazole (IPZ). Hydroxy ipronidazole may has similar mutagenic potential as the parent compound .

HY-126121R

*2-Hydroxy* Ibuprofen (Standard)**	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	COX
2-Hydroxy Ibuprofen (Standard) is the analytical standard of 2-Hydroxy Ibuprofen. This product is intended for research and analytical applications. 2-Hydroxy Ibuprofen is a metabolite of Ibuprofen. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively.

HY-W010254

*4′-Hydroxy-2′-methylacetophenone*	Infection Structural Classification Monophenols Epiphyllum oxypetalum (DC.) Haw. Cactaceae Classification of Application Fields Ketones, Aldehydes, Acids Source classification Phenols Plants Disease Research Fields	Parasite
4′-Hydroxy-2′-methylacetophenone, an aroma compound of red wines, is isolated from cv. Bobal grape variety. 4′-Hydroxy-2′-methylacetophenone has ciliate toxicity. 4′-Hydroxy-2′-methylacetophenone inhibits the growth of T. pyriformis, with an IC₅₀ of 0.65 mM .

HY-P2274

Argifin	Infection Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields	Parasite
Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms, with IC₅₀s of 0.025 μM, 6.4 μM , 1.1 μM and 4.5 μM for SmChiA (Serratia marcescens chitinaese A), SmChiB, Aspergillus fumigatus chitinase B1 and human chitotriosidase, respectively .

HY-N8047

*5-Hydroxy-7-(4'-hydroxy-3'-methoxyphenyl)-1-phenyl-3-heptanone*	Structural Classification Source classification Phenols Plants Curcuma longa Zingiberaceae	Others
5-Hydroxy-7-(4'-hydroxy-3'-methoxyphenyl)-1-phenyl-3-heptanone is a Phenols product that can be isolated from the rhizomes of Curcuma longa L. .

HY-N13284

*13-Hydroxy-9-octadecenoic acid*	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Fungal
13-Hydroxy-9-octadecenoic acid is a hydroxy unsaturated fatty acid (HUFA) that has anti-fungal activity .

HY-N7602

*10-Hydroxy* majoroside**	Plantaginaceae Natural Products Classification of Application Fields Source classification Other Diseases Plantago asiatica L. Plants Disease Research Fields	Others
10-Hydroxy majoroside is a methanol extract isolated from plantago asiatica .

HY-N0445

*2-Hydroxy-4-methoxybenzaldehyde*	Structural Classification Monophenols other families Classification of Application Fields Simple Phenylpropanols Source classification Other Diseases Phenols Phenylpropanoids Plants Disease Research Fields	Tyrosinase Bacterial
2-hydroxy-4-methoxybenzaldehyde is a potent tyrosinase inhibitor . 2-Hydroxy-4-methoxybenzaldehyde, an isomer of Vanillin, could be used to synthesis Urolithin M7

HY-W001663

*4'-Hydroxy-3'-methylacetophenone*	Infection Monophenols Classification of Application Fields Ketones, Aldehydes, Acids Source classification Rubiaceae Phenols Plants Disease Research Fields Coffea arabica L.	Bacterial
4'-Hydroxy-3'-methylacetophenone, a phenolic volatile compound, is isolated from Hawaiian green coffee beans (Coffea Arabica L.). 4'-Hydroxy-3'-methylacetophenone has potent antioxidant activities. 4'-Hydroxy-3'-methylacetophenone also can be used to synthesize heterocyclic compounds which have antimycobacterial activity .

HY-N8797

*Methyl 1-hydroxy-4-oxocyclohexaneacetate*	Structural Classification Erinacea anthyllis Link Ketones, Aldehydes, Acids Source classification Plants Compositae	Others
Methyl 1-hydroxy-4-oxocyclohexaneacetate (Compound 7) is a lactone. Methyl 1-hydroxy-4-oxocyclohexaneacetate is isolated from the natural Senecio scandens. Methyl 1-hydroxy-4-oxocyclohexaneacetate has anti-inflammatory andantibacterialactivity .

HY-W005327R

*1-Hydroxy-2-butanone (Standard)*	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Bacterial Drug Intermediate
1-Hydroxy-2-butanone (Standard) is the analytical standard of 1-Hydroxy-2-butanone. This product is intended for research and analytical applications. 1-Hydroxy-2-butanone is a natural compound isolated from Bomboo Juice. 1-Hydroxy-2-butanone acts as a key intermediate for ethambutol. Ethambutol has anti-tuberculosis effects[1][2].

HY-126121

*2-Hydroxy* Ibuprofen** (±)-2-hydroxy Ibuprofen	Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields Inflammation/Immunology	COX
2-Hydroxy Ibuprofen is a metabolite of Ibuprofen. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC₅₀s of 13 μM and 370 μM, respectively.

HY-N7971

*2-Hydroxy-1-Methoxyaporphine*	Cardiovascular Disease Alkaloids Structural Classification Monophenols Classification of Application Fields Source classification Phenols Nelumbo nucifera Gaertn. Plants Isoquinoline Alkaloids Disease Research Fields Nymphaeaceae	Endogenous Metabolite
2-Hydroxy-1-Methoxyaporphine is an alkaloid that can be isolated from Nelumbo nucifera. 2-Hydroxy-1-Methoxyaporphine is the major active ingredient of the Chinese traditional medicine Jiang-Zhi-Ning .

HY-135212

Hydroxy ipronidazole	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Hydroxy ipronidazole (Ipronidazole-OH) is a metabolite of nitroimidazole antibiotics, such as ipronidazole (IPZ). Hydroxy ipronidazole may has similar mutagenic potential as the parent compound .

HY-W015874R

*2-Hydroxy-2-methylbutanoic acid (Standard)*	Structural Classification Other disease Ketones, Aldehydes, Acids Source classification Disease markers Endogenous metabolite	Endogenous Metabolite
2-Hydroxy-2-methylbutanoic acid (Standard) is the analytical standard of 2-Hydroxy-2-methylbutanoic acid. This product is intended for research and analytical applications. 2-Hydroxy-2-methylbutanoic acid, an unusual metabolite, is associated with 2-hydroxyglutaric aciduria and maple syrup urine disease.

HY-W005327

*1-Hydroxy-2-butanone*	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Bacterial Drug Intermediate
1-Hydroxy-2-butanone is a natural compound isolated from Bomboo Juice. 1-Hydroxy-2-butanone acts as a key intermediate for ethambutol. Ethambutol has anti-tuberculosis effects .

HY-N7608

Beiwutine 10-hydroxy mesaconitine	Alkaloids Terpenoids Source classification Ranunculaceae Diterpenoids Aconitum carmichaeli Debx. Plants	Others
Beiwutine (10-Hydroxy mesaconitine) is a diester diterpenoid alkaloid .

HY-W007888

*2-Hydroxy-4-methylbenzaldehyde*	Structural Classification Monophenols Classification of Application Fields Ketones, Aldehydes, Acids Source classification Phenols Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
2-Hydroxy-4-methylbenzaldehyde is an endogenous metabolite.

HY-W008188

*3-Hydroxy-4-aminopyridine*	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
3-Hydroxy-4-aminopyridine is an endogenous metabolite.

HY-W016103

*1-Hydroxy-2-naphthoic acid*	Structural Classification Monophenols Classification of Application Fields Ketones, Aldehydes, Acids Source classification Phenols Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
1-Hydroxy-2-naphthoic acid is an endogenous metabolite.

HY-23195

*Potassium 2-hydroxy-2-methylsuccinate*	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Potassium 2-hydroxy-2-methylsuccinate is an endogenous metabolite.

HY-N13543

*5-Hydroxy-7-(4-hydroxy-3-methoxyphenyl)-1-phenylhept-4-en-3-one*	Zingiber officinale Roscoe Structural Classification Source classification Phenols Polyphenols Plants Zingiberaceae	Others
5-Hydroxy-7-(4-hydroxy-3-methoxyphenyl)-1-phenylhept-4-en-3-one is a natural product .

HY-N13416

*6-Hydroxy-7-methoxydihydroligustilide*	Structural Classification Natural Products Source classification Umbelliferae Plants Echinacea angustifolia DC.	Others
6-Hydroxy-7-methoxydihydroligustilide is a natural product .

HY-138545

*4-Hydroxy-6-methylcoumarin*	Structural Classification Ekebergia senegalensis Source classification Coumarins Phenylpropanoids Plants Meliaceae	Others
4-Hydroxy-6-methylcoumarin is a Coumarin product .

HY-N3505

*14-Hydroxy* sprengerinin C**	Classification of Application Fields Dipsacaceae Source classification Other Diseases Plants Dipsacus asper Disease Research Fields Steroids	Others
14-Hydroxy sprengerinin C is a steroidal compound found in Ophiopogon japonicus.

HY-W011474R

Geranylgeraniol (Standard)	Structural Classification Natural Products Microorganisms	NF-κB
Geranylgeraniol (Standard) is the analytical standard of Geranylgeraniol. This product is intended for research and analytical applications. Geranylgeraniol is an orally acitve vitamin K2 sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model ^[3][4].

HY-N10192

Aculene D	Infection Microorganisms Classification of Application Fields Terpenoids Sesquiterpenes Source classification Disease Research Fields	Endogenous Metabolite Bacterial
Aculene D, a fungal metabolite, shows quorum sensing (QS) inhibitory activity against Chromobacterium violaceum CV026, and could significantly reduce violacein production in N-hexanoyl-l-homoserine lactone (C6-HSL) induced C. violaceum CV026 cultures at sub-inhibitory concentrations .

HY-N8142

*6-Hydroxy-2-phenethylchromone*	Monophenols other families Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Phenols Plants Disease Research Fields	Others
6-Hydroxy-2-phenethylchromone possesses antioxidant activity .

HY-W002484R

*3-Hydroxy-4-methoxyacetophenone (Standard)*	Structural Classification other families Source classification Phenols Plants	Others
3-Hydroxy-4-methoxyacetophenone (Standard) is the analytical standard of 3-Hydroxy-4-methoxyacetophenone. This product is intended for research and analytical applications. 3-Hydroxy-4-methoxyacetophenone(Acetoisovanillone; Isoacetovanillone) is an active compound isolated from P. spinosa. Isoacetovanillone possesses anti-inflammatory activity and prevented injuries due to administration of acetic acid in the colon .

HY-22167R

*Methyl 2-hydroxy-4-methylvalerate (Standard)*	Structural Classification Natural Products Animals Source classification	Biochemical Assay Reagents
Methyl 2-hydroxy-4-methylvalerate (Standard) is the analytical standard of Methyl 2-hydroxy-4-methylvalerate. This product is intended for research and analytical applications. Methyl 2-hydroxy-4-methylvalerate is one of dominant volatile compounds in Zhenjiang aromatic vinegar. Methyl 2-hydroxy-4-methylvalerate is used for charting flavour biosynthesis networks of vinegar microbiota[1].

HY-N0662

Amentoflavone 5+ Cited Publications Didemethyl-ginkgetin	Structural Classification Flavonoids Classification of Application Fields Source classification Phenols Polyphenols Selaginellaceae Plants Biflavones Selaginella tamariscina (P. Beauv.) Spring Disease Research Fields Cancer	Reactive Oxygen Species (ROS) Apoptosis Bacterial Fungal RSV GABA Receptor
Amentoflavone (Didemethyl-ginkgetin) is a potent and orally active GABA(A) negative modulator. Amentoflavone also shows anti-inflammatory, antioxidative, anti-viral, anti-tumor, anti-radiation, anti-fungal, antibacterial activity. Amentoflavone induces apoptosis and cell cycle arrest at sub-G1 phase ^[3] .

Cat. No.	Product Name	Chemical Structure

HY-W008216S

HMMNI-d3
HMMNI-d₃ (Hydroxy Dimetridazole-d₃) is deuterium labeled HMMNI (HY-W008216). HMMNI (Hydroxy dimetridazole) is a hydroxy metabolite of Dimetridazol (HY-B1244). Dimetridazole is a nitroimidazole class agent that combats protozoan infections .

HY-N0504S2

Lovastatin-d3
Lovastatin-d₃ is deuterium labeled Lovastatin. Lovastatin is a cell-permeable HMG-CoA reductase inhibitor used to lower cholesterol.

HY-123672S

Lovastatin-d3 hydroxy acid sodium
Lovastatin-d₃ hydroxy acid (sodium) is the deuterium labeled Lovastatin hydroxy acid sodium. Lovastatin hydroxy acid sodium (Mevinolinic acid sodium) is a highly potent inhibitor of HMG-CoA reductase with a K_i of 0.6 nM .

HY-N0504S1

Lovastatin-d9
Lovastatin-d₉ is the deuterium labeled Lovastatin. Lovastatin is a cell-permeable HMG-CoA reductase inhibitor used to lower cholesterol.

HY-G0003S1

*Iloperidone metabolite Hydroxy* Iloperidone-d3**
Iloperidone metabolite Hydroxy Iloperidone-d₃ is the deuterium labeled Iloperidone metabolite Hydroxy Iloperidone .

HY-108263S

*3-Hydroxy* Midostaurin-d5**
3-Hydroxy Midostaurin-d₅ is a deuterium labeled 3-Hydroxy Midostaurin. 3-Hydroxy Midostaurin is a metabolite of PKC412, which effectively inhibits FMS-like tyrosine kinase-3 (FLT3) autophosphorylation with IC₅₀s of approximately 132 nM and 9.8 μM in culture medium and plasma, respectively .

HY-169892S

*4-Hydroxy* Nonenal Glutathione-d3**
4-Hydroxy Nonenal Glutathione-d₃ (4-HNE-GSH-d₃) is deuterium labeled 4-Hydroxy Nonenal Glutathione .

HY-W354610S

*N-(4-Hydroxy-3-methoxybenzyl)stearamide-d3*
N-(4-Hydroxy-3-methoxybenzyl)stearamide-d₃ is the deuterium labeled N-(4-hydroxy-3-methoxybenzyl)stearamide .

HY-139429S

*(−)-11-Hydroxy-Δ8-THC-d3*
(?)-11-Hydroxy-Δ8-THC-d₃ ((?)-11-Hydoxy-Δ8-Tetahydocaabiol-d₃) is deuterium labeled (?)-11-hydroxy-Δ8-THC .

HY-W012927S

*4-Hydroxy-5-methylfuran-3(2H)-one-d3*
4-Hydroxy-5-methylfuran-3(2H)-one-d₃ is deuterated labeled 4-Hydroxy-5-methylfuran-3(2H)-one (HY-W012927). 4-Hydroxy-5-methylfuran-3(2H)-one (Chicory furaneol) can be used to assay oxidoreductase activity. 4-Hydroxy-5-methylfuran-3(2H)-one is a kind of biological materials or organic compounds that are widely used in life science research .

HY-W021008S

*3-Hydroxy-4,5-dimethylfuran-2(5H)-one-d2*
3-Hydroxy-4,5-dimethylfuran-2(5H)-one-d₂ is deuterated labeled 3-Hydroxy-4,5-dimethylfuran-2(5H)-one.

HY-126121S

*2-Hydroxy* Ibuprofen-d6**
2-Hydroxy Ibuprofen-d₆ is the deuterium labeled 2-Hydroxy Ibuprofen. 2-Hydroxy Ibuprofen is a metabolite of Ibuprofen. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC₅₀s of 13 μM and 370 μM, respectively .

HY-10844S1

Pretomanid-d5
Pretomanid-d₅ is deuterated labeled Pretomanid (HY-10844). Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 μg/mL.

HY-12773AS2

*5-Hydroxy* Propafenone-d6 hydrochloride**
5-Hydroxy Propafenone-d₆ hydrochloride is deuterated labeled 5-Hydroxy Propafenone.

HY-12772S

Hydroxy Itraconazole-d8
Hydroxy Itraconazole-d₈ is the deuterium labeled Hydroxy Itraconazole. Hydroxy Itraconazole is an active metabolite of Itraconazole (ITZ), which is a triazole antifungal agent.

HY-12772S3

Hydroxy Itraconazole-d6
Hydroxy Itraconazole-d₆ (R-63373-d₆) is deuterium labeled Hydroxy Itraconazole. Hydroxy Itraconazole (Itraconazole metabolite Hydroxy Itraconazole; R-63373) is an active metabolite of Itraconazole (ITZ), which is a triazole antifungal agent.

HY-131543S

22-Hydroxy Mifepristone-d6

22-Hydroxy Mifepristone-d₆ is the deuterium labeled 22-Hydroxy Mifepristone (HY-131543). 22-Hydroxy Mifepristone (RU 42698) is an orally active hydroxylated alcoholic metabolite with antiprogestational and antiglucocorticoidal activities, which contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. The relative binding affinity of 22-Hydroxy Mifepristone to the human glucocorticoid receptor is 48% .

HY-W025101S

*Ethyl 3-hydroxy-3-methylbutanoate-d6*
Ethyl 3-hydroxy-3-methylbutanoate-d₆ is the deuterium labeled Ethyl 3-hydroxy-3-methylbutanoate .

HY-151930S1

*8′-Hydroxy* ABA-d2**
8′-Hydroxy ABA-d₂ is the deuterium labeled 8’-Hydroxy ABA .

HY-111975S5

*7'-Hydroxy* ABA-d7**
7'-Hydroxy ABA-d₇ is the deuterium labeled 7'-Hydroxy ABA .

HY-151930S

*8′-Hydroxy* ABA-d8**
8′-Hydroxy ABA-d₈ is the deuterium labeled 8’-Hydroxy ABA .

HY-111975S1

*7'-Hydroxy* ABA-d2**
7'-Hydroxy ABA-d₂2 is the deuterium labeled 7'-Hydroxy ABA .

HY-115354S

*4-Hydroxy* Alprazolam-d5**
4-Hydroxy Alprazolam-d5 (4-Hydroxyalprazolam-d5; RS-4-Hydroxyalprazolam-d5) is the deuterium labeled 4-hydroxy Alprazolam (HY-115354) .

HY-U00050S

(E)-10-Hydroxynortriptyline-d3
(E)-10-Hydroxynortriptyline-d₃ is a deuterium labeled (E)-10-Hydroxy Nortriptyline. (E)-10-Hydroxy Nortriptyline is a metabolite of Nortriptyline. Nortriptyline is a tricyclic antidepressant and the main active metabolite of Amitriptyline, and is used to relieve the symptoms of depression .

HY-B1189S

Meglutol-d3
Meglutol-d₃ is the deuterium labeled Meglutol . Meglutol is an antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids, and inhibits the activity of hydroxymethylglutarryl CoA reductases, which is the rate limiting enzyme in the biosynthesis of cholesterol.

HY-121385S1

Hydroxy Bosentan-d4
Hydroxy Bosentan-d₄ is deuterium labeled Hydroxy bosentan. Hydroxy bosentan (Ro 48-5033) is a primary metabolite of Bosentan (BOS) metabolized by the cytochrome P450 system in the liver. Ro 48-5033 assists BOS pharmacologically, retaining 10%-20% activities .

HY-121385S

Hydroxy Bosentan-d6
Hydroxy Bosentan-d₆ is deuterium labeled Hydroxy bosentan. Hydroxy bosentan (Ro 48-5033) is a primary metabolite of Bosentan (BOS) metabolized by the cytochrome P450 system in the liver. Ro 48-5033 assists BOS pharmacologically, retaining 10%-20% activities .

HY-B1159S1

Nitroxoline-d5
Nitroxoline-d₅ (8-Hydroxy-5-nitroquinoline-d₅) is deuterium labeled Nitroxoline. Nitroxoline (8-Hydroxy-5-nitroquinoline), an antibiotic, is an orally active antibiofilm agent. Nitroxoline reduces the formation and induces the dispersal of Pseudomonas aeruginosa biofilms by chelation of iron and zinc. Nitroxoline can be used for the urinary tract infections and cancer research ^[3].

HY-12773AS

*5-Hydroxy* Propafenone-d5 hydrochloride**
5-Hydroxy Propafenone-d₅ (hydrochloride) is the deuterium labeled 5-Hydroxy Propafenone.

HY-118714S

*α-Hydroxy* alprazolam-d5**
α-Hydroxy alprazolam-d₅ (U 40125-d₅; alpha-Hydroxyalprazolam-d₅) is the deuterium labled α-hydroxy alprazolam (HY-118714).

HY-17461S3

Cortisone-d2
Cortisone-d₂ is the deuterium labeled Cortisone. Cortisone (17-Hydroxy-11-dehydrocorticosterone), an oxidized metabolite of Cortisol (a Glucocorticoid). Cortisone acts as an immunosuppressant and anti-inflammatory agent. Cortisone can partially intervene in binding of Glucocorticoid to Glucocorticoid-receptor at high concentrations ^[3] .

HY-124352S

2-Nonyl-3-hydroxy-4-quinolone-d4

2-Nonyl-3-hydroxy-4-quinolone-d₄ (C9-PQS-d₄) is deuterium labeled 2-Nonyl-3-hydroxy-4-quinolone. 2-nonyl-3-hydroxy-4-Quinolone (C9-PQS) is a quinolone compound produced by P. aeruginosa and other related bacterias. 2-nonyl-3-hydroxy-4-Quinolone is a quorum sensing (QS) signal molecule that controls the expression of many virulence genes as a function of cell population density .

HY-B0648S

Medroxyprogesterone-d3
Medroxyprogesterone-d₃ is the deuterium labeled Medroxyprogesterone. Medroxyprogesterone is a progestin, a synthetic variant of the human hormone progesterone and a potent progesterone receptor agonist.

HY-32351AS

Calcifediol-d6 monohydrate
Calcifediol-d₆ monohydrate is the deuterium labeled Calcifediol monohydrate. Calcifediol monohydrate (25-hydroxy Vitamin D3 monohydrate), is an effective VDR ligand and VD supplement. Calcifediol is a prohormone of the vitamin D endocrine system (VDES) and is hydroxylated in the liver to produce the active form, calcitriol. Calcifediol can rapidly increase serum VD levels ^[3].

HY-B1689AS

Methantheline-d3 bromide
Methantheline-d₃ (bromide) is the deuterium labeled Methantheline bromide .

HY-I0637S

Isovanillin-d3
Isovanillin-d₃ is the deuterium labeled Isovanillin . Isovanillin is an aldehyde oxidase inhibitor . Antispasmodic activities ^[3]. Antidiarrheal activities .

HY-165678S

*(±)-10-Hydroxy-12(Z)-Octadecenoic acid-d5*
(±)-10-Hydroxy-12(Z)-Octadecenoic acid-d₅ (10-Hydoxy-cis-12-Octadeceoic Acid-d₅) is deuterium labeled (±)-10-Hydroxy-12(Z)-Octadecenoic acid .

HY-113323S

3-Methoxy-4-hydroxyphenylglycol-d3
3-Methoxy-4-hydroxyphenylglycol-d₃ is the deuterium labeled 3-Methoxy-4-hydroxyphenylglycol.

HY-B1773AS5

Sodium Propionate-d3
Sodium Propionate-d₃ is the deuterium labeled Sodium Propionate .

HY-17413S

Zidovudine-d3
Zidovudine-d₃ is the deuterium labeled Zidovudine. Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection.

HY-W010305S

*5-Ethyl-3-hydroxy-4-methylfuran-2(5H)-one-d4*
5-Ethyl-3-hydroxy-4-methylfuran-2(5H)-one-d₄ is deuterated labeled 5-Ethyl-3-hydroxy-4-methylfuran-2(5H)-one.

HY-113031S

16α-Hydroxydehydroepiandrosterone-d6
16α-Hydroxydehydroepiandrosterone-d₆ (16α-Hydroxy-DHEA-d₆) is the deuterium labeled 16α-Hydroxydehydroepiandrosterone .

HY-136883S

Benzophenone-9-d6
Benzophenone-9-d₆ (Disodium 3,3'-carbonylbis[4-hydroxy-6-methoxybenzenesulphonate]-d₆) is deuterium labeled Benzophenone-9 .

HY-32351S

Calcifediol-d3
Calcifediol-d₃ is a deuterium labeled Calcifediol. Calcifediol, is an effective VDR ligand and VD supplement. Calcifediol is a prohormone of the vitamin D endocrine system (VDES) and is hydroxylated in the liver to produce the active form, calcitriol. Calcifediol can rapidly increase serum VD levels ^[3].

HY-32349S

Ercalcidiol-d3
Ercalcidiol-d₃ is the deuterium labeled Ercalcidiol. Ercalcidiol is a metabolite of Vitamins D2. Ercalcidiol can be used as an indicator of vitamins D status .

HY-B0715S3

Pentoxifylline-d3

Pentoxifylline-d₃ (BL-191-d₃) is deuterium labeled Pentoxifylline. Pentoxifylline (BL-191), a haemorheological agent, is an orally active non-selective phosphodiesterase (PDE) inhibitor, with immune modulation, anti-inflammatory, hemorheological, anti-fibrinolytic and anti-proliferation effects. Pentoxifylline can be used for the research of peripheral vascular disease, cerebrovascular disease and a number of other conditions involving a defective regional microcirculation ^[3].

HY-B0607S

Nitisinone-d3

Nitisinone-d₃ (NTBC-d₃) is deuterium labeled Nitisinone. Nitisinone is an orally active, competitive and reversible 4-hydroxyphenylpyruvate dioxygenase (4-HPPD) inhibitor with an IC₅₀ of 173 nM. Nitisinone promotes tyrosine accumulation in a dose-dependent manner. nitisinone can be used in studies of hereditary tyrosinemia type 1 (HT-1) (a rare genetic disorder) and albinism ^[3] .

HY-113031S1

16α-Hydroxydehydroepiandrosterone-d5
16α-Hydroxydehydroepiandrosterone-d₅ (16α-Hydroxy-DHEA-d₅) is the deuterium labeled 16α-Hydroxydehydroepiandrosterone (HY-113031) .

HY-70002S

Deutenzalutamide
Deutenzalutamide (Enzalutamide-d₃) is a developed deuterium labeled Enzalutamide (MDV3100). Enzalutamide is an androgen receptor (AR) antagonist with an IC50 of 36 nM in LNCaP prostate cells .

HY-B0457AS

Clomipramine-d3
Clomipramine-d₃ is the deuterium labeled Clomipramine. Clomipramine is a serotonin transporter (SERT), norepinephrine transporter (NET) dopamine transporter (DAT) blocker with K_i of 0.14, 54 and 3 nM, respectively .

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Species:	Human (13) Bovine (1)
Tag:	GFP (1) His (13) Strep (3) Myc (1) Trx (1) Flag (7)
Source:	HEK293 (8) E. coli Cell-free (1) E. coli (5)


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Lovastatin-d<sub>3</sub> hydroxy acid

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