1. Epigenetics TGF-beta/Smad Neuronal Signaling GPCR/G Protein
  2. PKC 5-HT Receptor
  3. R 59-022 (Standard)

R 59-022 (Standard) is the analytical standard of R 59-022. This product is intended for research and analytical applications. R 59-022 (DKGI-I) is a DGK inhibitor (IC50: 2.8 µM). R 59-022 inhibits the phosphorylation of OAG to OAPA. R 59-022 is a 5-HT Receptor antagonist, and activates protein kinase C (PKC). R 59-022 potentiates thrombin-induced diacylglycerol production in platelets and inhibits phosphatidic acid production in neutrophils.

For research use only. We do not sell to patients.

R 59-022 (Standard) Chemical Structure

R 59-022 (Standard) Chemical Structure

CAS No. : 93076-89-2

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Description
Molecular Weight

459.58

Formula

C27H26FN3OS

CAS No.
SMILES

O=C1C(CCN(CC/2)CCC2=C(C3=CC=CC=C3)/C4=CC=C(F)C=C4)=C(C)N=C5N1C=CS5

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Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
R 59-022 (Standard)
Cat. No.:
HY-107613R
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