2. Metabolic Enzyme/Protease
  3. LDLR
  4. VH4127 TFA

VH4127 TFA is a cyclic peptide targeting the low density lipoprotein receptor (LDLR) with a KD of 18 nM for hLDLR. VH4127 TFA specifically binds to rodent and human epidermal growth factor (EGF) homology domain of LDLR.

For research use only. We do not sell to patients.

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VH4127 TFA Chemical Structure

VH4127 TFA Chemical Structure

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Based on 1 publication(s) in Google Scholar

Other Forms of VH4127 TFA:

VH4127 TFA Related Antibodies

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Description

VH4127 TFA is a cyclic peptide targeting the low density lipoprotein receptor (LDLR) with a KD of 18 nM for hLDLR. VH4127 TFA specifically binds to rodent and human epidermal growth factor (EGF) homology domain of LDLR[1][2].

Molecular Weight

1034.35 (free base)

Formula

C40H71N15O9S4.xC2HF3O2
Appearance

Solid

Sequence

Pr-cyclo[{d-Cys}-Met-Thz-Arg-Leu-Arg-Gly-Pen]-NH2
Sequence Shortening

Pr-cyclo[{d-Cys}-M-Thz-RLRG-Pen]-NH2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Purity & Documentation
References
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VH4127 TFA Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

VH4127VH 4127VH-4127LDLRLow-density lipoprotein receptorcyclic peptidelow density lipoproteinnon-natural amino acidInhibitorinhibitorinhibit

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VH4127 TFA
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HY-P10697A
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