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  3. Lipid A-11

Lipid A-11 (A-11) can be used to synthesize lipid-like nanoparticles (LNPs) for delivery of nucleic acids.

For research use only. We do not sell to patients.

Lipid A-11

Lipid A-11 Chemical Structure

CAS No. : 2996998-09-3

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Description

Lipid A-11 (A-11) can be used to synthesize lipid-like nanoparticles (LNPs) for delivery of nucleic acids[1].

Molecular Weight

1013.39

Formula

C55H100N2O14

CAS No.
Appearance

Liquid (Density: 1.038±0.06 g/cm3)

Color

Colorless to light yellow

SMILES

O=C(N(CCOC(CC(COC(CCCCCCCC)=O)COC(CCCCCCCC)=O)=O)CCOC(CC(COC(CCCCCCCC)=O)COC(CCCCCCCC)=O)=O)OCCN(C)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

Ethanol : ≥ 50 mg/mL (49.34 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.9868 mL 4.9339 mL 9.8679 mL
5 mM 0.1974 mL 0.9868 mL 1.9736 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.84%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
Ethanol 1 mM 0.9868 mL 4.9339 mL 9.8679 mL 24.6697 mL
5 mM 0.1974 mL 0.9868 mL 1.9736 mL 4.9339 mL
10 mM 0.0987 mL 0.4934 mL 0.9868 mL 2.4670 mL
15 mM 0.0658 mL 0.3289 mL 0.6579 mL 1.6446 mL
20 mM 0.0493 mL 0.2467 mL 0.4934 mL 1.2335 mL
25 mM 0.0395 mL 0.1974 mL 0.3947 mL 0.9868 mL
30 mM 0.0329 mL 0.1645 mL 0.3289 mL 0.8223 mL
40 mM 0.0247 mL 0.1233 mL 0.2467 mL 0.6167 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Lipid A-11
Cat. No.:
HY-170333
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