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1927

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35

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59

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137

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11

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27

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Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B1004
    Dinitolmide
    1 Publications Verification

    Zoalene

    		 Parasite Infection
    Dinitolmide (Zoalene) is an orally active anticoccidial agent used as a fodder additive. Dinitolmide has a wide anticoccidial spectrum with no effect on host immunity. Dinitolmide mainly acts on the first generation merozoite stage of coccidia and also has an inhibitory effect on the sporulation process of oocysts. Dinitolmide has anti-Toxoplasma gondii effect in vitro with an EC50 of 3.625 μg/mL. Dinitolmide can be used to inhibits infections caused by Eimeria tenella .
    Dinitolmide
  • HY-121573
    α-Acetyldigoxin

    		Biochemical Assay Reagents Cardiovascular Disease
    α-Acetyldigoxin can be used in heart failure related research and is orally available. The bioavailability of α-Acetyldigoxin is lower than that of β-Acetyldigoxin when administered orally and intravenously .
    α-Acetyldigoxin
  • HY-E70090
    T7 RNA polymerase

    		DNA/RNA Synthesis Others
    T7 RNA polymerase is a polymerase expressed by Escherichia coli from the RNA polymerase gene of T7 bacteriophage. T7 RNA polymerase is highly specific and involved in in vitro transcription (IVT) of mRNA. In the presence of Mg 2+, T7 RNA polymerase only uses the single-stranded or double-stranded DNA containing the T7 promoter sequence as a template, and uses NTP as a substrate to synthesize RNA complementary to the single-stranded DNA downstream of the promoter .
    T7 RNA polymerase
  • HY-157316
    TZ-NBD

    		Fluorescent Dye Others
    TZ-NBD is a dual-channel sensitive fluorescence probe that exhibits fast response, and excellent selectivity to detect biothiols in vitro and in vivo .
    TZ-NBD
  • HY-N13139
    Dexylosyltubeimoside Ⅲ

    		Others Cancer
    Dexylosyltubeimoside Ⅲ (compound 3) is a cyclic disoside that can be isolated from Actinostemma lobatum MAXIM. Dexylosyltubeimoside Ⅲ has in vitro anticancer activity and inhibits the growth of human esophageal cancer cell line ECA109 (IC50=22.37 μM), lung cancer cell line A549 (IC50=27.27 μM) and gastric cancer cell line MGC-803 (IC50=36.85 μM) .
    Dexylosyltubeimoside Ⅲ
  • HY-134375
    cAIMP

    Cyclic Adenosine-inosine Monophosphate

    		 NF-κB IFNAR Inflammation/Immunology
    cAIMP (Cyclic Adenosine-Inosine Monophosphate) is an effective synthetic cyclic dinucleotide. cAIMP activates IRF and NF-κB in the THP1 human monocyte reporter cell line (THP1-Dual). cAIMP induces the secretion of IFNs and pro-inflammatory cytokines in vitro in human blood, with an EC50 of 6.4 μmol/L .
    cAIMP
  • HY-P3516
    Barusiban

    FE-200440

    		 Oxytocin Receptor Endocrinology
    Barusiban (FE-200440) is an oxytocin receptor (OT-R) antagonist (Ki=0.8 nM), inhibits OT-induced contraction. Barusiban can be used in preterm labor (PTL), in vitro fertilisation (IVF) and infertility research .
    Barusiban
  • HY-150145
    Cy5-UTP

    		Biochemical Assay Reagents Others
    Cy5-UTP is a substrate for terminal deoxynucleotidyl transferase (TdT). Cy5-UTP can be used to lable RNA probes through in vitro transcription (Excitation/Emission: 650/665 nm). Cy5-labeled mRNA emits orange fluorescence .
    Cy5-UTP
  • HY-157390
    DPP-4-IN-9

    		Dipeptidyl Peptidase Metabolic Disease
    DPP-4-IN-9 (compound 6l) is a potent inhibitor of dipeptidyl peptidase DPP-4 (IC50: 8.22 nM). DPP-4-IN-9 has antihyperglycemic activity .
    DPP-4-IN-9
  • HY-162856
    TRPV1-IN-2

    		TRP Channel Neurological Disease
    TRPV1-IN-2 ((R)-32) is a TRPV1 inhibitor. TRPV1-IN-2 has protective effects on ED epilepsy models .
    TRPV1-IN-2
  • HY-155241
    α-Amylase/α-Glucosidase-IN-4

    		Glycosidase Amylases Metabolic Disease
    α-Amylase/α-Glucosidase-IN-4 (compound 5) is a dual inhibitor of α-glucosidase (Glucosidase) and α-amylase (Amylases) with IC50s of 0.15 μM and 1.10 μM, respectively. α-Amylase/α-Glucosidase-IN-4 has potential antidiabetic activity .
    α-Amylase/α-Glucosidase-IN-4
  • HY-E70400
    Thermostable T7 RNA Polymerase

    		DNA/RNA Synthesis Others
    Thermostable T7 RNA Polymerase is a thermostable version of T7 RNA Polymerase (HY-E70090). Compared with T7 RNA Polymerase, it has high temperature resistance and stable activity. T7 RNA polymerase is a polymerase expressed by Escherichia coli from the RNA polymerase gene of T7 bacteriophage. T7 RNA polymerase is highly specific and involved in in vitro transcription (IVT) of mRNA. In the presence of Mg 2+, T7 RNA polymerase only uses the single-stranded or double-stranded DNA containing the T7 promoter sequence as a template, and uses NTP as a substrate to synthesize RNA complementary to the single-stranded DNA downstream of the promoter .
    Thermostable T7 RNA Polymerase
  • HY-W419570
    (Rac)-BX 048

    		P2Y Receptor Cardiovascular Disease
    (Rac)-BX 048 is a BX 048 racemate. BX 048 is a P2Y12 receptor antagonist. BX 048 inhibits ADP-induced platelet aggregation in human, dog and rat whole blood. BX 048 also inhibits Arachidonic acid (HY-109590) induced platelet aggregation (IC50 of 15 μM) .
    (Rac)-BX 048
  • HY-15197
    ABT-046

    		Acyltransferase Metabolic Disease
    ABT-046 is a potent, selective, and orally active acyl CoA:diacylglycerol acyltransferase 1 (DGAT-1) inhibitor with IC50s of both 8 nM against human and mouse DGAT-1 .
    ABT-046
  • HY-P1139
    Cortistatin-8

    PCFWKTCK

    		 GHSR Metabolic Disease
    Cortistatin-8 (CST-8; PCFWKTCK), a neuropeptide, is a GHS-R1a antagonist by counteracting the response of ghrelin on gastric acid secretion. Cortistatin-8 can modulate GH release from somatotroph cells. Cortistatin-8 is a synthetic CST-analogue devoid of any binding affinity to SST-R but capable to bind the GHS-R1a. Cortistatin-8 can exert antagonistic effects on ghrelin actions either in vitro or in vivo in animals .
    Cortistatin-8
  • HY-A0096R
    Iloprost (Standard)

    Ciloprost (Standard); ZK 36374 (Standard)

    		 Reference Standards Prostaglandin Receptor Endogenous Metabolite Endocrinology Cancer
    Iloprost (Standard) is the analytical standard of Iloprost. This product is intended for research and analytical applications. Iloprost (ZK 36374; Ciloprost) is a prostacyclin (PGI2) analogue, involves in embryo development and inflammation improvement, and inhibits tumor metastasis. Iloprost can be used for peripheral vascular research .
    Iloprost (Standard)
  • HY-A0096
    Iloprost
    5 Publications Verification

    Ciloprost; ZK 36374

    		 Prostaglandin Receptor Endogenous Metabolite Cardiovascular Disease Endocrinology Cancer
    Iloprost (ZK 36374; Ciloprost) is a prostacyclin (PGI2) analogue, involves in embryo development and inflammation improvement, and inhibits tumor metastasis. Iloprost can be used for peripheral vascular research .
    Iloprost
  • HY-W015627
    3,5-Dichloropyridine

    		Drug Intermediate Inflammation/Immunology Cancer
    3,5-dichloropyridine is a drug intermediate that can be used to synthesize metal-organic framework (MOF) materials and P2X7 receptor antagonists .
    3,5-Dichloropyridine
  • HY-N10373
    Caffeoyl alcohol

    		Others Others
    Caffeoyl alcohol is a monomer constituting Catechyl lignin. Catechyl lignin is a linear homopolymer of caffeyl alcohol, a natural source of carbon fiber and high-value chemicals .
    Caffeoyl alcohol
  • HY-162812
    H3R antagonist 4

    		Apoptosis Cholinesterase (ChE) Tau Protein Ferroptosis Histamine Receptor Neurological Disease
    H3R antagonist 4 (compound 11L) was a dual inhibitor of cholinesterase and histamine receptor (H3R), with corresponding IC50 of 7.04 μM (eeAChE), 9.73 μM (hAChE)(reversible) and 1.09 nM (H3R) , respectively. H3R antagonist 4 inhibited the aggregation of Aβ1-42 induced by itself and Cu 2+ (95.48% and 88.63%) , and degraded the Aβ1-42 fibrils induced by itself and Cu 2+ (80.16% and 89.30%) . H3R antagonist 4 chelate biometals such as Cu 2+, Zn 2+, Al 3+, and Fe 2+. H3R antagonist 4 significantly reduced tau protein hyperphosphorylation induced by Aβ1-42 and inhibited RSL-3-induced apoptosis and ferroptosis in PC12 cells. H3R antagonist 4 had the best blood-brain barrier permeability and intestinal absorption in hCMEC/D3 and hPepT1-MDCK cells.H3R antagonist 4 ameliorates learning and memory impairment in a mouse model of Alzheimer's disease induced by scopolamine (HY-N0296) .
    H3R antagonist 4
  • HY-155239
    VEGFR-2-IN-35

    		VEGFR Cancer
    VEGFR-2-IN-35 (compound 7) is a potent VEGFR-2 inhibitor with IC50=37 nM. VEGFR-2-IN-35 inhibits MCF-7 and HCT 116 cancer cells with IC50 values of 10.56 and 7.07 μM, respectively .
    VEGFR-2-IN-35
  • HY-N0500
    Mogroside III

    		Glycosidase Autophagy Metabolic Disease Endocrinology
    Mogroside III is a triterpenoid glycoside. Mogroside III exhibits maltase inhibitory effect with an IC50 value of 1.6 mM. Mogroside III enhances oocyte developmental potential by promoting autophagy in cumulus cells. Mogroside III, as the active ingredient of the low-polarity glycoside component (L-SGgly), L-SGgly can increase serum GLP-1 levels, improve insulin resistance, and reduce IL-6 levels, and has hypoglycemic, lipid-regulating and anti-inflammatory effects. Mogroside III can be used for the studies of type 2 diabetes mellitus (T2DM) and assisted reproductive technology .
    Mogroside III
  • HY-156261
    Beef extract

    		Biochemical Assay Reagents Others
    Beef extract is a common ingredient in the preparation of biological culture media .
    Beef extract
  • HY-16750
    Radalbuvir

    GS-9669

    		 HCV Infection
    Radalbuvir (GS-9669) is a non-nucleoside inhibitor of nonstructural protein 5B (NS5B) RNA-dependent RNA polymerase (RdRp). Radalbuvir shows strong anti-HCV potency (GT1a intrinsic EC50 = 2.9 nM, GT1b EC50 = 6 nM) .
    Radalbuvir
  • HY-P5232
    Tetrapeptide-21

    		Collagen Metabolic Disease
    Tetrapeptide-21 is a bioactive peptide composed of four amino acids. Tetrapeptide-21 effectively enhances the vitality of human dermal fibroblasts. Tetrapeptide-21 upregulates the expression of key extracellular matrix (ECM) genes and promotes the synthesis of ECM proteins (such as type I collagen, hyaluronic acid synthase 1, and fibronectin). Tetrapeptide-21 has the efficacy of anti-wrinkle and improving skin elasticity, and has been reported to be used as a cosmetic ingredient .
    Tetrapeptide-21
  • HY-119893
    Diamfenetide

    		Parasite Infection
    Diamfenetide is used for the study of Fasciola hepatica infections in vitro. Diamfenetide leads to irreversible paralysis in vitro of immature and adult Fasciola hepatica .
    Diamfenetide
  • HY-P99590A
    Sotatercept (mIgG2a)

    RAP-011

    		 TGF-β Receptor TGF-beta/Smad Cardiovascular Disease Metabolic Disease
    Sotatercept (mIgG2a) (RAP-011), the murine homolog of Sotatercept (ACE-011) (HY-P99590), is a soluble activin receptor type IIA (ActRIIA) ligand trap. Sotatercept (mIgG2a) inhibits the binding of activin A and other members of the TGF-β superfamily (such as Activin A/B, GDF11 and BMP9/10) to their receptors by combining and neutralizing them, thereby regulating cell proliferation and differentiation. Sotatercept (mIgG2a) mainly inhibits the SMAD2/3 signaling pathway, and can be used in various diseases such as chronic kidney disease. Sotatercept (mIgG2a) reduces the expression of erythropoietic hepcidin (ERFE), regulates iron metabolism, and promotes red blood cell production. Sotatercept (mIgG2a) has a dual effect of promoting bone formation (anabolic) and inhibiting bone resorption (catabolic) .
    Sotatercept (mIgG2a)
  • HY-D1451
    PKH 26
    25+ Cited Publications

    		 Fluorescent Dye Others
    PKH 26 is a red fluorescent dye, PKH 26 can stably bind to the lipid region of cell membrane and emit red fluorescence (Ex/Em=551/567 nm), which is mainly used for in vitro cell labeling, in vitro cell proliferation studies and in vivo and in vitro cell tracing studies .
    PKH 26
  • HY-G0003R
    Iloperidone metabolite Hydroxy Iloperidone (Standard)

    P88 (Standard); Hydroxy Iloperidone (Standard)

    		 Reference Standards Drug Metabolite Others
    Diamfenetide (Standard) is the analytical standard of Diamfenetide. This product is intended for research and analytical applications. Diamfenetide is used for the study of Fasciola hepatica infections in vitro.?Diamfenetide?leads to irreversible paralysis in vitro of immature and adult Fasciola hepatica .
    Iloperidone metabolite Hydroxy Iloperidone (Standard)
  • HY-119893R
    Diamfenetide (Standard)

    		Reference Standards Parasite Infection
    Diamfenetide (Standard) is the analytical standard of Diamfenetide. This product is intended for research and analytical applications. Diamfenetide is used for the study of Fasciola hepatica infections in vitro.?Diamfenetide?leads to irreversible paralysis in vitro of immature and adult Fasciola hepatica .
    Diamfenetide (Standard)
  • HY-101631
    Levophacetoperane hydrochloride

    		Dopamine Transporter Neurological Disease
    Levophacetoperane inhibits in vitro in a competitive manner, norepinephrin uptake and dopamine uptake.
    Levophacetoperane hydrochloride
  • HY-19735
    KJ Pyr 9
    5+ Cited Publications

    		 c-Myc Autophagy Cancer
    KJ Pyr 9 is an inhibitor of MYC with a Kd of 6.5 nM in in vitro assay.
    KJ Pyr 9
  • HY-W796158
    Z-DEVD-CMK

    		Cathepsin Inflammation/Immunology
    Z-DEVD-CMK is an irreversible inhibitor of most of the cathepsins in vitro .
    Z-DEVD-CMK
  • HY-121374
    Cardanol diene

    		Tyrosinase Infection
    Cardanol diene is a phenol found in cashew nut shell liquid that inhibits tyrosinase with an IC50 value of 52.5 μM in vitro.1 Cardanol diene is also used to synthesize cardanol-metal complexes that inhibit uropathogenic E. coli biofilm formation.
    Cardanol diene
  • HY-N6635
    trans-Nerolidol

    		Fungal Infection Cancer
    trans-Nerolidol improves the anti-proliferative effect of Doxorubicin (DOX) (HY-15142A) against intestinal cancer and breast cancer cells in vitro. trans-Nerolidol increases accumulation of DOX inside cells in vitro. trans-Nerolidol activates apoptosis in vivo .
    trans-Nerolidol
  • HY-142052
    Anhydrotetracycline

    5a(6)-Anhydrotetracycline

    		 Antibiotic Infection
    Anhydrotetracycline shows dose-dependent and potent inhibition of tetracycline destructases in vitro .
    Anhydrotetracycline
  • HY-156615
    Igermetostat

    		Histone Methyltransferase Cancer
    Igermetostat is EZH2 inhibitor, used in cancer research in vivo and in vitro .
    Igermetostat
  • HY-A0163CR
    trans-Clopenthixol dihydrochloride (Standard)

    (E)-Clopenthixol dihydrochloride (Standard)

    		 Antibiotic Bacterial Parasite Reference Standards Infection
    trans-Clopenthixol (dihydrochloride) (Standard) is the analytical standard of trans-Clopenthixol (dihydrochloride). This product is intended for research and analytical applications. trans-Clopenthixol ((E)-Clopenthixol) dihydrochloride is an antibiotic agent, without neuroleptic effect. trans-Clopenthixol can be used to inhibit Pseudomonas aeruginosa and Plasmodium falciparum in vitro[1][2].
    trans-Clopenthixol dihydrochloride (Standard)
  • HY-100236
    Madrasin
    5+ Cited Publications

    DDD00107587

    		 DNA/RNA Synthesis Cancer
    Madrasin (DDD00107587) is a splicing inhibitor that prevents formation of both splicing intermediates and products in vitro and interferes with one or more early steps in the pathway of spliceosome assembly. Madrasin also can inhibit pre-mRNA splicing in vitro and modify splicing of endogenous pre-mRNA in cells .
    Madrasin
  • HY-B0108
    Daptomycin
    20+ Cited Publications

    LY146032

    		 Bacterial Antibiotic Infection Cancer
    Daptomycin is a lipopeptide antibiotic with rapid in vitro bactericidal activity against gram-positive organisms.
    Daptomycin
  • HY-N0077
    Ginkgolic Acid
    10+ Cited Publications

    Ginkgolic acid (15:1); Ginkgolic acid I; Romanicardic acid

    		 E1/E2/E3 Enzyme Cancer
    Ginkgolic Acid is a natural compound that inhibits SUMOylation with an IC50 of 3.0 μM in in vitro assay.
    Ginkgolic Acid
  • HY-N1213
    Sprengerinin C

    		Others Cancer
    Sprengerinin is a potential angiogenesis inhibitor. Sprengerinin exerts anti-tumorigenic effects in vitro .
    Sprengerinin C
  • HY-N13890
    Arginomycin

    		Antibiotic Bacterial Fungal Infection
    Arginomycin is a nucleoside antibiotic that inhibits the growth of Gram-positive bacteria and fungi in vitro .
    Arginomycin
  • HY-148294
    Monogalactosyl diglyceride

    		Bacterial Fungal Infection
    Monogalactosyl diglyceride is a antimicrobial. Monogalactosyl diglyceride has antibacterial activity and antifungal activity in vitro .
    Monogalactosyl diglyceride
  • HY-N13883
    Aerocavin

    		Antibiotic Bacterial Infection
    Aerocavin is an antibiotic that is active against both Gram-positive and Gram-negative bacteria in vitro .
    Aerocavin
  • HY-156998
    Troxacitabine triphosphate

    TRX-TP

    		 Nucleoside Antimetabolite/Analog Cancer
    Troxacitabine triphosphate (TRX-TP) is a good substrate for replicative and repair DNA polymerases in vitro .
    Troxacitabine triphosphate
  • HY-135214
    GA11

    		Aldehyde Dehydrogenase (ALDH) Cancer
    GA11 is an ALDH inhibitor that shows activity against glioblastoma both in vitro and in vivo .
    GA11
  • HY-125979
    TSPC

    		Phytohormone Others
    TSPC is a phytohormone gibberellin (GA) perception inhibitor with an IC50 value of 10 μM in vitro .
    TSPC
  • HY-N14599
    Resorthiomycin

    		Antibiotic Bacterial Infection Cancer
    Resorthiomycin is a an antitumor antibiotic that can inhibit L5178Y of leukemia cells in vitro .
    Resorthiomycin
  • HY-N12294
    Ciwujianoside D2

    		Lipase Metabolic Disease
    Ciwujianoside D2, a saponin compound, can enhance pancreatic lipase activity in vitro .
    Ciwujianoside D2

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