3-Iodothyronamine hydrochloride

Cat. No.: HY-135065 Purity: 99.5%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

3-Iodothyronamine (hydrochloride) is an endogenous and rapid-acting derivative of thyroid hormone. 3-Iodothyronamine potently activates an orphan G protein-coupled receptor in vitro (TAAR1) and induced hypothermia in vivo on a rapid time scale. 3-Iodothyronamine can be used for the research of congestive heart failure.

For research use only. We do not sell to patients.

3-Iodothyronamine hydrochloride Chemical Structure

CAS No. : 788824-64-6

Size	Stock	Quantity
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

or Bulk Inquiry

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of 3-Iodothyronamine hydrochloride:

3-Iodothyronamine-d₄ hydrochloride In-stock

Featured Recommendations

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

Biological Activity
Purity & Documentation
References
Customer Review

Description

Molecular Weight

391.63

Formula

C₁₄H₁₅ClINO₂

CAS No.

788824-64-6

Appearance

Solid

Color

White to off-white

SMILES

OC1=CC=C(OC2=CC=C(CCN)C=C2I)C=C1.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility

In Vitro:

DMSO : 25 mg/mL (63.84 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.5534 mL	12.7672 mL	25.5343 mL
5 mM	0.5107 mL	2.5534 mL	5.1069 mL
10 mM	0.2553 mL	1.2767 mL	2.5534 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.5%

Select Batch:

Data Sheet (266 KB) SDS (538 KB)

COA (244 KB)

Handling Instructions (2659 KB)

References

[1]. Hart ME, et al. Trace amine-associated receptor agonists: synthesis and evaluation of thyronamines and related analogues. J Med Chem. 2006 Feb 9;49(3):1101-12. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.5534 mL	12.7672 mL	25.5343 mL	63.8358 mL
	5 mM	0.5107 mL	2.5534 mL	5.1069 mL	12.7672 mL
	10 mM	0.2553 mL	1.2767 mL	2.5534 mL	6.3836 mL
	15 mM	0.1702 mL	0.8511 mL	1.7023 mL	4.2557 mL
	20 mM	0.1277 mL	0.6384 mL	1.2767 mL	3.1918 mL
	25 mM	0.1021 mL	0.5107 mL	1.0214 mL	2.5534 mL
	30 mM	0.0851 mL	0.4256 mL	0.8511 mL	2.1279 mL
	40 mM	0.0638 mL	0.3192 mL	0.6384 mL	1.5959 mL
	50 mM	0.0511 mL	0.2553 mL	0.5107 mL	1.2767 mL
	60 mM	0.0426 mL	0.2128 mL	0.4256 mL	1.0639 mL