1. Protein Tyrosine Kinase/RTK
  2. c-Fms
  3. GW2580 (Standard)

GW2580 (Standard) is the analytical standard of GW2580. This product is intended for research and analytical applications. GW2580 is an orally bioavailable and selective inhibitor of c-Fms kinase which completely inhibits human cFMS kinase in vitro at 0.06 μM. GW2580 acts as a competitive inhibitor of ATP binding to the cFMS kinase and inhibits colony-stimulating-factor-1 signaling.

For research use only. We do not sell to patients.

GW2580 (Standard) Chemical Structure

GW2580 (Standard) Chemical Structure

CAS No. : 870483-87-7

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Description
Molecular Weight

366.41

Formula

C20H22N4O3

CAS No.
SMILES

NC1=NC(N)=C(CC2=CC(OC)=C(OCC3=CC=C(OC)C=C3)C=C2)C=N1

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
GW2580 (Standard)
Cat. No.:
HY-10917R
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