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Serine Racemase (SR)

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ASCT (5) MASTL (4) Scavenger Receptor Class B type I (SR-BI） (2) Ser/Thr Kinase (7) Ser/Thr Protease (85) Serine Racemase (SR) (1) SHMT (7) SRPK (3) STK33 (1) 5 alpha Reductase (2) 5-HT Receptor (8) Acyltransferase (2) Adrenergic Receptor (9) Akt (4) Amino Acid Derivatives (88) Amino Acid Oxidase (1) AMPK (1) Anaplastic lymphoma kinase (ALK) (3) Androgen Receptor (1) Angiotensin Receptor (8) Angiotensin-converting Enzyme (ACE) (1) Antibiotic (8) Antifolate (3) AP-1 (2) APC (3) Apoptosis (51) Aryl Hydrocarbon Receptor (3) ATM/ATR (2) Aurora Kinase (2) Autophagy (17) Bacterial (29) Bcl-2 Family (4) Beta-lactamase (5) Biochemical Assay Reagents (27) c-Fms (2) c-Kit (3) c-Met/HGFR (2) Calcineurin (1) Calcium Channel (14) CaMK (1) Cannabinoid Receptor (8) Carboxylesterase (CES) (3) Casein Kinase (4) Caspase (6) Cathepsin (8) CD38 (1) CDK (16) Ceramidase (1) Cholecystokinin Receptor (2) Cholinesterase (ChE) (4) Complement System (1) COX (6) Cyclophilin (1) Cytochrome P450 (4) Dengue Virus (1) Dipeptidyl Peptidase (5) Discoidin Domain Receptor (1) DNA/RNA Synthesis (5) Dopamine Receptor (3) Dopamine Transporter (1) Drug Derivative (3) Drug Isomer (1) Drug Metabolite (5) EAAT (3) EGFR (3) Elastase (4) Endogenous Metabolite (52) Epigenetic Reader Domain (3) Estrogen Receptor/ERR (1) Eukaryotic Initiation Factor (eIF) (1) FAAH (6) Factor Xa (11) FAK (4) Flavivirus (5) FLT3 (2) Fluorescent Dye (6) Free Fatty Acid Receptor (1) Fungal (7) Furin (2) GABA Receptor (4) GCGR (2) Glucosylceramide Synthase (GCS) (1) GSK-3 (2) HCV (6) HCV Protease (3) HDAC (2) HMG-CoA Reductase (HMGCR) (2) HPV (1) HSP (3) IGF-1R (1) iGluR (4) IKK (5) Influenza Virus (3) Insulin Receptor (2) Integrin (1) Interleukin Related (3) Isotope-Labeled Compounds (44) JAK (2) JNK (3) Kinesin (1) KLF (2) Leukotriene Receptor (2) LIM Kinase (LIMK) (2) Liposome (6) Lipoxygenase (2) LXR (5) mAChR (3) MAGL (8) MAP4K (10) MAPKAPK2 (MK2) (2) MARCKS (1) mGluR (4) MHC (1) Microtubule/Tubulin (1) Mixed Lineage Kinase (2) MNK (3) Molecular Glues (1) Monoamine Oxidase (1) Mucin (1) nAChR (1) NADPH Oxidase (2) NEKs (1) Neurokinin Receptor (6) Neuropeptide Y Receptor (1) Neurotensin Receptor (5) NF-κB (6) NO Synthase (1) Opioid Receptor (5) Orphan Receptor (1) p38 MAPK (6) PAI-1 (6) Parasite (6) PD-1/PD-L1 (4) PDGFR (2) PDK-1 (1) Penicillin-binding protein (PBP) (1) PGC-1α (2) Phosphatase (6) Phosphoglycerate Dehydrogenase (PHGDH) (8) Phospholipase (4) PI3K (3) Pim (1) PKA (4) PKC (8) Platelet-activating Factor Receptor (PAFR) (1) Polo-like Kinase (PLK) (1) Potassium Channel (2) PPAR (11) Prolyl Endopeptidase (PREP) (3) PROTACs (5) Protease Activated Receptor (PAR) (4) Proteasome (5) RAR/RXR (1) Ras (3) Reference Standards (29) Renin (2) RET (1) REV-ERB (9) RIP kinase (8) ROCK (2) ROR (9) SARS-CoV (12) Serotonin Transporter (1) SGK (1) Sigma Receptor (2) Sirtuin (2) Small Interfering RNA (siRNA) (2) Sodium Channel (3) STING (5) Tau Protein (1) TGF-β Receptor (2) Thrombin (12) Thyroid Hormone Receptor (3) TMV (4) TNF Receptor (6) Toll-like Receptor (TLR) (1) Tyrosinase (1) ULK (1) Vasopressin Receptor (2) VEGFR (4) Virus Protease (7) Wnt (5) Xanthine Oxidase (2) β-catenin (1)
By Research Areas:	Cancer (222) Cardiovascular Disease (72) Endocrinology (14) Infection (79) Inflammation/Immunology (90) Metabolic Disease (89) Neurological Disease (87)
Click Chemistry:	Azide (1) Alkynes (1)
Oligonucleotides:	Phospholipids (8) siRNA drugs (2) Polymers (6) siRNAs (2)

730

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

142

Peptides

MCE Kits

Inhibitory Antibodies

Natural
Products

268

Recombinant Proteins

Isotope-Labeled Compounds

163

Antibodies

Click Chemistry

Oligonucleotides

Targets Recommended: Serine Racemase (SR) Microtubule‐associated serine/threonine kinase (MAST) Scavenger Receptor Class B type I (SR-BI） SRPK SHMT Ser/Thr Protease STK33 ASCT Ser/Thr Kinase Serpin MASTL Enteropeptidase

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W005308

*N-BOC-DL-serine* methyl ester**	Amino Acid Derivatives	Cancer
N-BOC-DL-serine methyl ester is a Serine derivative. N-BOC-DL-serine methyl ester is used for the synthesis of α,β-dehydro-α-amino acid. N-BOC-DL-serine methyl ester is also used for the synthesis of anti-cancer agent, such as quinazolinone derivative that inhibits PI3K activity, and tricyclic pyrolopyranopyridines that inhibits protein kinase activity .

HY-153433

Serine Hydrolase inhibitor-21	Cholinesterase (ChE)	Neurological Disease
Serine Hydrolase inhibitor-21 (compound 8), a pyridine, is a serine hydrolase inhibitor with a K_i of 429 nM for BuChE. Serine Hydrolase inhibitor-21 has the potential for Alzheimer's disease research .

HY-W048674

Fmoc-Ser(Ac)-OH Fmoc-O-acetyl-L-Serine	Amino Acid Derivatives	Infection
Fmoc-Ser(Ac)-OH (Fmoc-O-acetyl-L-serine) is a Serine derivative. Fmoc-Ser(Ac)-OH can be used for the preparation of broad-spectrum coronavirus membrane fusion inhibitor .

HY-18345

SR 49059 2 Publications Verification	Vasopressin Receptor	Cardiovascular Disease Endocrinology
SR 49059 (SR-49059) is a potent, orally active, selective vasopressin V1a antagonist with a K_i vaule of 1.4 nM .

HY-W039102

N-Fmoc-N,O-dimethyl-L-serine	Amino Acid Derivatives	Cancer
N-Fmoc-N,O-dimethyl-L-serine is a serine derivative that can be used for coibamide A synthesis. Coibamide A is a marine natural product with potent antiproliferative activity against human cancer cells .

HY-115881

SR-1114	PROTACs Epigenetic Reader Domain	Cancer
SR-1114 is a PROTAC degrader targeting ENL. SR-1114 degrades ENL in a CRBN-dependent manner and selectively downregulates ENL target genes. SR-1114 can promote the differentiation of acute myeloid leukemia cells. SR-1114 can be used in tumor research. (Pink: ENL ligand (HY-145409); Black: Linker; Blue: E3 Ligand (HY-14658)) .

HY-13751

SR-31747	Sigma Receptor	Inflammation/Immunology
SR-31747 is a sigma ligand with immunosuppressive and anti-inflammatory properties. SR-31747 blocks cell proliferation by inhibiting sterol isomerase .

HY-145409

SR-0813	Epigenetic Reader Domain	Cancer
SR-0813 is a potent and selective ENL/AF9 YEATS domain inhibitor. SR-0813 has IC₅₀ and EC₅₀ values of 25 nM and 205 nM for ENL YEATS domain, respectively. SR-0813 has IC₅₀ and EC₅₀ values of 311 nM and 76 nM (CETSA) for AF9 YEATS domain, respectively. SR-0813 binds MAP3K19 with over 100-fold lower affinity (K_d=3.5 μM) than ENL YEATS (K_d=30 nM). SR-0813 can be used for the research of acute leukemia .

HY-111487

*α-Methylacyl-CoA racemase* 1**	Endogenous Metabolite	Metabolic Disease Cancer
α-methylacyl-CoA racemase 1 is an enzyme that catalyzes a key chiral inversion step in the metabolism of branched-chain fatty acids, and used as a maker in prostate and other cancer.

HY-105259

SR 43845	Renin	Cardiovascular Disease
SR 43845 is a renin inhibitor. SR 43845 decreases blood pressure and inhibits plasma renin activity. SR 43845 can be used for hypertension research .

HY-106716

SR 41378	Drug Derivative	Neurological Disease
SR 41378 is an orally active aminopyrazine derivative. SR 41378 has anticonvulsant, antianxiety and hypnotic activities .

HY-149292

SR-4133	Casein Kinase	Cancer
SR-4133 is a potent and highly CK1ε selective inhibitor with an IC₅₀ of 58 nM. SR-4133 binds to the ATP-binding site of CK1ε. SR-4133 displays nanomolar growth inhibition of bladder cancer cells, and inhibits the phosphorylation of 4E-BP1 .

HY-120853

SR-4326	Drug Derivative	Others
SR-4326 is an active compound.

HY-120144

SR-8993	Opioid Receptor	Neurological Disease
SR-8993 is a highly selective nociceptin receptor agonist that can penetrate the blood-brain barrier and has the activity of reducing alcohol intake and relieving withdrawal anxiety. SR-8993 has shown mild anxiolytic effects in animal models and can effectively reverse anxiety caused by acute alcohol withdrawal. SR-8993 further reduces restricted drinking, operant responses for alcohol, and increased drinking induced by long-term intermittent exposure to alcohol. SR-8993 also reduces stress- and cue-related alcohol-seeking relapse .

HY-P2130

SR 42128	Renin	Cardiovascular Disease
SR 42128 is a potent renin inhibitor. SR 42128 potently inhibits primate renins whereas other animal renins are much less inhibited .

HY-100277

Mifobate 1 Publications Verification SR-202	PPAR	Metabolic Disease
Mifobate (SR-202) is a potent and specific PPARγ antagonist. Mifobate (SR-202) selectively inhibits Thiazolidinedione (TZD)-induced PPARγ transcriptional activity (IC₅₀=140 μM). Mifobate (SR-202) does not affect basal or ligand-stimulated transcriptional activity of PPARα, PPARβ, or the farnesoid X receptor (FXR). Mifobate (SR-202) shows antiobesity and antidiabetic effects .

HY-135674

SR-318	p38 MAPK TNF Receptor	Inflammation/Immunology Cancer
SR-318 is a potent and highly selective p38 MAPK inhibitor with IC₅₀s of 5 nM, 32 nM and 6.11 μM for p38α, p38β and p38α/β, respectively. SR-318 potently inhibits the TNF-α release in whole blood with an IC₅₀ of 283 nM. SR-318 has anti-cancer and anti-inflammatory activity .

HY-120542

SR 1824	PPAR	Metabolic Disease
SR 1824 is a non-agonist PPARγ ligand that blocks Cdk5-mediated phosphorylation. SR 1824 has anti-diabetic effects .

HY-13300

SR-3677 1 Publications Verification	ROCK Autophagy	Cancer
SR-3677 is a potent and selective ROCK-II inhibitor with an IC₅₀ of ~3 nM.

HY-12829

SR-3306	JNK	Neurological Disease
SR-3306 is a selective, potent, highly brain penetrant JNK inhibitor.

HY-101454

SR0987 2 Publications Verification	ROR	Inflammation/Immunology Cancer
SR0987, a SR1078 analog, is a RORγt agonist, with an EC₅₀ of 800 nM. SR0987 increases IL17 expression while repressing the expression of PD-1 .

HY-108907

SR-1277	Casein Kinase	Cancer
SR-1277 is a potent, selective and ATP competitive CK1δ/ε inhibitor, with IC₅₀s of 49 nM and 260 nM, respectively. SR-1277 also inhibits FLT3, CDK4/cyclin D1, CDK6/cyclin D3 and CDK9/cyclin K, with IC₅₀s of 305 nM, 1340 nM, 311 nM and 109 nM, respectively. SR-1277 can be used for the research of cancer .

HY-122681

SR-16435	Opioid Receptor	Neurological Disease
SR-16435 is a nociceptin/orphanin FQ (NOP)/μ-opioid receptor partial agonist, with high binding affinity (NOP receptor K_i=7.49; μ-Opioid receptor K_i=2.70). SR-16435 can relieve pain .

HY-138007

SR-1903	ROR PPAR LXR	Metabolic Disease Inflammation/Immunology
SR-1903 is an inverse agonist of RORγ and PPARγ (IC₅₀ of ∼100 nM and 209 nM for RORγ and PPARγ, respectively) and a LXR agonist. SR-1903 exhibits anti-inflammatory and anti-diabetic efficacy in collagen-induced arthritis and diet-induced obesity mouse models .

HY-120785A

SR1555 hydrochloride	ROR	Inflammation/Immunology
SR1555 hydrochloride is the hydrochloride salt form of SR1555 (HY-120785). SR1555 hydrochloride is an inverse agonist for retinoic acid receptor-related orphan nuclear receptor γ (RORγ) with an IC₅₀ of 1 μM. SR1555 hydrochloride inhibits the development and function of pro-inflammatory TH17 cell, increases the frequency of anti-inflammatory T regulatory (Treg) cells. SR1555 hydrochloride can be used for research about autoimmune diseases .

HY-15870A

(6E)-SR 11302	AP-1	Inflammation/Immunology Cancer
(6E)-SR 11302 is a E-isomer of SR 11302. SR 11302 is an activator protein-1 (AP-1) transcription factor inhibitor. SR 11302 is a retinoid that specifically inhibits AP-1 activity without activating the transcription of retinoic acid response element (RARE) .

HY-107596

SR-3576	JNK	Others
SR-3576 is a highly potent and selective JNK3 inhibitor with an IC₅₀ of 7 nM .

HY-117248

SR-3737	JNK p38 MAPK	Neurological Disease
SR-3737 is a JNK3 and p38 inhibitor (IC₅₀: 12 and 3 nM) .

HY-13751A

SR-31747 free base	Sigma Receptor	Inflammation/Immunology
SR-31747 free base is a sigma ligand with immunosuppressive and anti-inflammatory properties. SR-31747 blocks cell proliferation by inhibiting sterol isomerase .

HY-156458

SR-29065	REV-ERB	Inflammation/Immunology
SR-29065 is a selective REV-ERBα agonist, can be used for autoimmune disorders research .

HY-W841840

SR94	Sirtuin	Neurological Disease Cancer
SR94, a SR17 derivative, is a SIRT2 inhibitor that contains an arbitrary 6-member ring and different R2 groups. SR94 is promising for research of cancer, ischemia-reperfusion and neurodegenerative diseases .

HY-167208

SR-302	Discoidin Domain Receptor p38 MAPK	Inflammation/Immunology Cancer
SR-302 is a potent and selectivity DDR/p38 inhibitor, with IC₅₀ values of 0.125, 0.023 and 0.018 μM for p38α, DDR1 and DDR2, respectively. SR-302 can be used for the research of fibrotic disorders, such as renal and pulmonary fibrosis, atherosclerosis, and various forms of cancer .

HY-15870

SR 11302 15+ Cited Publications	AP-1	Inflammation/Immunology Cancer
SR 11302 is an activator protein-1 (AP-1) transcription factor inhibitor. SR 11302 is a retinoid that specifically inhibits AP-1 activity without activating the transcription of retinoic acid response element (RARE) .

HY-107664A

SR 142948 dihydrochloride	Neurotensin Receptor	Neurological Disease
SR 142948 dihydrochloride is an orally active and selective non-peptide neurotensin receptor (NT) antagonist with IC₅₀s of 1.19 nM, 0.32 nM, 3.96 nM in h-NTR1-CHO cells, HT-29 cells, and adult rat brain, respectively. SR 142948 dihydrochloride antagonizes NT-induced inositol monophosphate formation in HT-29 cells with an IC₅₀ of 3.9 nM. SR 142948 dihydrochloride blocks hypothermia, analgesia and steering behavior induced by NT in vivo. SR 142948 dihydrochloride shows blood-brain permeability and can be used in study of psychiatric disorders .

HY-107664

SR 142948	Neurotensin Receptor	Neurological Disease
SR 142948 is an orally active and selective non-peptide neurotensin receptor (NT) antagonist with IC₅₀s of 1.19 nM, 0.32 nM, 3.96 nM in h-NTR1-CHO cells, HT-29 cells, and adult rat brain, respectively. SR 142948 antagonizes NT-induced inositol monophosphate formation in HT-29 cells with an IC50 of 3.9 nM. SR 142948 blocks hypothermia, analgesia and steering behavior induced by NT in vivo. SR 142948 shows blood-brain permeability and can be used in study of psychiatric disorders .

HY-131454

SR-717 10+ Cited Publications	STING	Inflammation/Immunology Cancer
SR-717 is a non-nucleotide STING agonist with EC₅₀s of 2.1 μM and 2.2 μM in ISG-THP1 (WT) and ISG-THP1 cGAS KO (cGAS KO) cell lines, respectively. SR-717 is a stable cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) mimetic. Antitumor activity .

HY-101491S

SR-18292-d9	Isotope-Labeled Compounds PGC-1α Autophagy	Metabolic Disease
SR-18292-d₉ is the deuterium labeled SR-18292 (HY-101491). SR-18292 is a PPAR gamma coactivator-1α (PGC-1α) inhibitor, which increases PGC-1α acetylation, suppresses gluconeogenic gene expression and reduces glucose production in hepatocytes .

HY-13300A

SR-3677 dihydrochloride	ROCK Autophagy	Cancer
SR-3677 dihydrochloride (compound 5) is a potent and selective ROCK-I and ROCK-II inhibitor with an IC₅₀ values of 56 nM and 3 nM .

HY-13421R

SR1001 (Standard)	REV-ERB ROR	Inflammation/Immunology
SR1001 (Standard) is the analytical standard of SR1001. This product is intended for research and analytical applications. SR1001 is a selective RORα and RORγt inverse agonist with Kis 172 and 111 nM, respectively.

HY-161362

SR-3-65	PI3K	Cancer
SR-3-65 (compound 6) is a Indisulam (HY-13650) derivative,and inhibits the migration of gastric cancer cells. SR-3-65 attenuates PI3K/AKT/GSK-3β/β-catenin signaling pathway .

HY-117413

SR-17398	ULK	Cancer
SR-17398 is an inhibitor for Unc-51-Like Kinase 1 (ULK1) with an IC₅₀ of 22.4 μM .

HY-130250

SR-4835 10+ Cited Publications	CDK Apoptosis	Cancer
SR-4835 is a potent, highly selective and ATP competitive dual inhibitor of CDK12/CDK13 (CDK12: IC₅₀=99 nM, K_d=98 nM; CDK13: K_d=4.9 nM). SR-4835 acts in synergy with DNA-damaging chemotherapy and PARP inhibitors and provokes triple-negative breast cancer (TNBC) cell death .

HY-118961

SR31527 chloride	Kinesin	Cancer
SR31527 chloride is a potent KIFC1 inhibitor with an IC₅₀ value of 6.6 µM. SR31527 chloride decreases cell viability and colony formation .

HY-100277R

Mifobate (Standard) SR-202 (Standard)	Reference Standards PPAR	Metabolic Disease
Mifobate (Standard) is the analytical standard of Mifobate. This product is intended for research and analytical applications. Mifobate (SR-202) is a potent and specific PPARγ antagonist. Mifobate (SR-202) selectively inhibits Thiazolidinedione (TZD)-induced PPARγ transcriptional activity (IC₅₀=140 μM). Mifobate (SR-202) does not affect basal or ligand-stimulated transcriptional activity of PPARα, PPARβ, or the farnesoid X receptor (FXR). Mifobate (SR-202) shows antiobesity and antidiabetic effects .

HY-117516

SR10067	REV-ERB	Neurological Disease Metabolic Disease
SR10067 is a potent, selective and brain penetrant REV-ERB agonist. SR10067 has high affinity for Rev-Erbβ and Rev-Erbα with IC₅₀ values of 160 nM and 170 nM, respectively. SR10067 can be used for the research of metabolic diseases and neuropsychiatric disorders .

HY-124822

COH-SR4 2 Publications Verification	AMPK	Metabolic Disease Cancer
COH-SR4 is an AMPK activator. COH-SR4 shows potent anti-proliferative activities against leukemia, melanoma, breast and lung cancers. COH-SR4 inhibits adipocyte differentiation via AMPK activation. COH-SR4 can be used for the research of obesity and related metabolic disorders .

HY-11077

SR 146131	Cholecystokinin Receptor	Metabolic Disease Endocrinology
SR 146131 is a potent, orally available, and selective nonpeptide (cholecystokinin 1) receptor agonist.

HY-107664B

SR 142948 TFA	Neurotensin Receptor	Neurological Disease
SR 142948 TFA is an orally active and selective non-peptide neurotensin receptor (NT) antagonist with IC₅₀s of 1.19 nM, 0.32 nM, 3.96 nM in h-NTR1-CHO cells, HT-29 cells, and adult rat brain, respectively. SR 142948 TFA antagonizes NT-induced inositol monophosphate formation in HT-29 cells with an IC₅₀ of 3.9 nM. SR 142948 TFA blocks hypothermia, analgesia and steering behavior induced by NT in vivo. SR 142948 TFA shows blood-brain permeability and can be used in study of psychiatric disorders .

HY-136909

SR33805	Calcium Channel	Cardiovascular Disease
SR33805 is a potent Ca ²⁺ channel antagonist, with EC₅₀s of 4.1 nM and 33 nM in depolarized and polarized conditions, respectively. SR33805 blocks L-type but not T-type Ca ²⁺ channels. SR33805 can be used for the research of acute or chronic failing hearts .

HY-169898S

SR 144528-d3	Isotope-Labeled Compounds	Others
SR 144528-d₃ is deuterium labeled SR 144528 .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0650

L-Serine 5+ Cited Publications Serine	Structural Classification Classification of Application Fields Anti-aging Source classification Endocrine diseases Amino acids Endogenous metabolite Microorganisms Disease markers Nervous System Disorder Disease Research Fields Cardiovascular System Disorder Cancer	Endogenous Metabolite Bacterial
L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-15130

DL-O-Phosphoserine	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
DL-O-Phosphoserine is a normal metabolite in human biofluids and is a mixture of phosphoserine with two stereochemical structures (D-type and L-type O-phospho-serine). O-phospho-L-serine is a competitive inhibitor of **serine racemase and phagocytosis*. O-phospho-L-serine* inhibits the enzymatic reaction by competing with the active site of serine racemase, thereby affecting the production of D-serine. O-phospho-L-serine also mimics the phosphatidylserine head group, binds to the phosphatidylserine receptor, interferes with phagocytic signal transduction, and partially blocks the phagocytosis of apoptotic cells by cells. O-phospho-L-serin can be used in the research of retinal regeneration, bone repair, and insect growth and development .

HY-N0650R

*L-Serine* (Standard)** Serine (Standard)	Structural Classification Microorganisms Source classification Disease markers Endocrine diseases Amino acids Nervous System Disorder Endogenous metabolite Cardiovascular System Disorder	Reference Standards Endogenous Metabolite Bacterial
L-Serine (Standard) is the analytical standard of L-Serine. This product is intended for research and analytical applications. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-Y0507

DL-Serine 1 Publications Verification	Infection Structural Classification other families Classification of Application Fields Ketones, Aldehydes, Acids Source classification Plants Disease Research Fields	TMV
DL-Serine, a fundamental metabolite, is a mixture of D-Serine and L-Serine. DL-Serine has antiviral activity against the multiplication of tobacco mosaic virus (TMV) .

HY-15129

O-Phospho-L-serine 2 Publications Verification L-Serine O-phosphate; L-SOP	Structural Classification Human Gut Microbiota Metabolites Immune System Disorder Microorganisms Ketones, Aldehydes, Acids Source classification Disease markers Endogenous metabolite	mGluR Endogenous Metabolite
O-Phospho-L-serine is the immediate precursor to L-cystein in the serine synthesis pathway, and an agonist at the group III mGluR receptors (mGluR4, mGluR6, mGluR7, and mGluR8); O-Phospho-L-serine also acts as a weak antagonist for mGluR1 and a potent antagonist for mGluR2 .

HY-100808

D-Serine 1 Publications Verification (R)-Serine	Structural Classification Human Gut Microbiota Metabolites Microorganisms Source classification Amino acids Endogenous metabolite	iGluR Endogenous Metabolite
D-Serine ((R)-Serine), an endogenous amino acid involved in glia-synapse interactions that has unique neurotransmitter characteristics, is a potent co-agonist at the NMDA glutamate receptor. D-Serinee has a cardinal modulatory role in major NMDAR-dependent processes including NMDAR-mediated neurotransmission, neurotoxicity, synaptic plasticity, and cell migration .

HY-101409A

*O-Acetyl-L-serine* hydrochloride**	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
O-Acetyl-L-serine hydrochloride is an endogenous metabolite.

HY-Y0507R

*DL-Serine* (Standard)**	Structural Classification other families Ketones, Aldehydes, Acids Source classification Plants	Reference Standards TMV
DL-Serine (Standard) is the analytical standard of DL-Serine. This product is intended for research and analytical applications. DL-Serine, a fundamental metabolite, is a mixture of D-Serine and L-Serine. DL-Serine has antiviral activity against the multiplication of tobacco mosaic virus (TMV)[1].

HY-100808R

*D-Serine* (Standard)** (R)-Serine (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms Source classification Amino acids Endogenous metabolite	Reference Standards iGluR Endogenous Metabolite
D-Serine (Standard) is the analytical standard of D-Serine. This product is intended for research and analytical applications. D-Serine ((R)-Serine), an endogenous amino acid involved in glia-synapse interactions that has unique neurotransmitter characteristics, is a potent co-agonist at the NMDA glutamate receptor. D-Serinee has a cardinal modulatory role in major NMDAR-dependent processes including NMDAR-mediated neurotransmission, neurotoxicity, synaptic plasticity, and cell migration[1][2].

HY-101409AR

*O-Acetyl-L-serine* hydrochloride (Standard)**	Structural Classification Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Reference Standards Endogenous Metabolite
O-Acetyl-L-serine (hydrochloride) (Standard) is the analytical standard of O-Acetyl-L-serine (hydrochloride). This product is intended for research and analytical applications. O-Acetyl-L-serine hydrochloride is an endogenous metabolite.

HY-101409

O-Acetylserine O-Acetyl-L-Serine	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Source classification Other Diseases Amino acids Endogenous metabolite Disease Research Fields	Endogenous Metabolite
O-Acetylserine (O-Acetyl-L-serine) is an intermediate in the biosynthesis of the amino acid cysteine in bacteria and plants.

HY-119759

Lipoxamycin	Infection Structural Classification Microorganisms Antifungal Classification of Application Fields Antibiotics Source classification Disease Research Disease Research Fields Other Antibiotics	Fungal
Lipoxamycin is an antifungal antibiotic and a potent serine palmitoyltransferase inhibitor with an IC₅₀ of 21 nM .

HY-134222A

N-Acetylserine N-Acetyl-L-Serine	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
N-Acetylserine (N-Acetyl-L-serine) can bind to CysB apoprotein. N-acetylserine is the physiological inducer of cysteine biosynthesis. N-Acetylserine can stimulate in vitro cysJIH transcription .

HY-101409R

O-Acetylserine (Standard) O-Acetyl-L-Serine (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms Source classification Amino acids Endogenous metabolite	Reference Standards Endogenous Metabolite
O-Acetylserine (Standard) is the analytical standard of O-Acetylserine. This product is intended for research and analytical applications. O-Acetylserine (O-Acetyl-L-serine) is an intermediate in the biosynthesis of the amino acid cysteine in bacteria and plants.

HY-N4332

Rivulariapeptolides 1121	Natural Products Microorganisms Source classification	Ser/Thr Protease
Rivulariapeptolides 1121 is a high potent and selective serine protease inhibitor with IC₅₀ values of 35.52 nM, 13.24 nM and 48.05 nM for chymotrypsin, elastase and proteinase K, respectively .

HY-113013

Hydroxypyruvic acid β-Hydroxypyruvic acid; 3-Hydroxypyruvic acid	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Hydroxypyruvic acid (β-Hydroxypyruvic acid) is an intermediate in the metabolism of glycine, serine and threonine. Hydroxypyruvic acid is a substrate for serine-pyruvate aminotransferase and glyoxylate reductase/hydroxypyruvate reductase. Hydroxypyruvic acid is involved in the metabolic disorder which is the dimethylglycine dehydrogenase deficiency pathway.

HY-113013A

Hydroxypyruvic acid lithium hydrate β-Hydroxypyruvic acid lithium hydrate; 3-Hydroxypyruvic acid lithium hydrate	Structural Classification Human Gut Microbiota Metabolites Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Hydroxypyruvic acid lithium hydrate (β-Hydroxypyruvic acid lithium hydrate) is an intermediate in the metabolism of glycine, serine and threonine. Hydroxypyruvic acid lithium hydrate is a substrate for serine-pyruvate aminotransferase and glyoxylate reductase/hydroxypyruvate reductase. Hydroxypyruvic acid lithium hydrate is involved in the metabolic disorder which is the dimethylglycine dehydrogenase deficiency pathway.

HY-N4331

Rivulariapeptolides 1185	Natural Products Microorganisms Source classification	Ser/Thr Protease
Rivulariapeptolides 1185 is a high potent and selective serine protease inhibitor with IC₅₀ values of 13.17 nM, 23.59 nM and 55.26 nM for chymotrypsin, elastase and proteinase K, respectively .

HY-N4333

Rivulariapeptolides 988	Natural Products Microorganisms Source classification	Ser/Thr Protease
Rivulariapeptolides 988 is a high potent and selective serine protease inhibitor with IC₅₀ values of 95.46 nM, 15.29 nM and 85.50 nM for chymotrypsin, elastase and proteinase K, respectively .

HY-113024

Pristanic acid	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Pristanic acid is an endogenous metabolite present in Blood that can be used for the research of Alpha Methylacyl CoA Racemase Deficiency and Zellweger Syndrome .

HY-113067

Phytanic acid	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Phytanic acid is an endogenous metabolite present in Blood that can be used for the research of Zellweger Syndrome, Alpha Methylacyl CoA Racemase Deficiency, Rhizomelic Chondrodysplasia Punctata and Infantile Refsum Disease .

HY-18234A

Leupeptin hemisulfate 40+ Cited Publications	Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Inflammation/Immunology Disease Research Fields	Cathepsin Ser/Thr Protease Virus Protease
Leupeptin hemisulfate is a broad-spectrum, membrane-permeable protease inhibitor. Leupeptin hemisulfate potently inhibits *serine, cysteine* and threonine proteases. Leupeptin hemisulfate inhibits M ^pro (the main protease of SARS-CoV-2) and also has anti-inflammatory activity .

HY-18234AR

Leupeptin hemisulfate (Standard)	Structural Classification Natural Products Microorganisms Source classification	Reference Standards Cathepsin Ser/Thr Protease Virus Protease
Leupeptin (hemisulfate) (Standard) is the analytical standard of Leupeptin (hemisulfate). This product is intended for research and analytical applications. Leupeptin hemisulfate is a broad-spectrum, membrane-permeable protease inhibitor. Leupeptin hemisulfate potently inhibits serine, cysteine and threonine proteases. Leupeptin hemisulfate inhibits Mpro (the main protease of SARS-CoV-2) and also has anti-inflammatory activity[1][2][3].

HY-A0183

Phosphatidylserine Phospholipids, phosphatidylSerines; Serine glycerophosphatides	Animals Source classification	Akt TGF-β Receptor
Phosphatidylserine (Phospholipids) is a well-conserved anti-inflammatory and immunosuppressive signal. Phosphatidylserine is involved in membrane translocation and the activation of protein kinase C, participating in Akt signaling through its interaction with PIP3. The local exposure of Phosphatidylserine can interact with complement and other proteins, promoting microglial phagocytosis during critical periods of synaptic refinement. Phosphatidylserine can promote blood coagulation in the extracellular environment and acts as a "eat me" signal to clear out apoptotic cells. Phosphatidylserine can suppress inflammation in tissues by inducing TGF-β secretion and inhibiting immune responses .

HY-139568

Deutarserine CTP-692	Structural Classification Neurological Disease Classification of Application Fields Source classification Amino acids Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Deutarserine is a deuterium modified analog of endogenous D-serine (CTP 692), which is used in the research of adults with schizophrenia .

HY-N5182

Chymostatin B	Structural Classification Natural Products Microorganisms Source classification	Others
Chymostatin B is a subtype of chymostatin characterized by a valine residue. Chymostatin inhibits chymotrypsin, papain, and other serine/cysteine endopeptidases .

HY-N5180

Chymostatin A	Structural Classification Natural Products Microorganisms Source classification	Others
Chymostatin A is a subtype of chymostatin characterized by a leucine residue. Chymostatin inhibits chymotrypsin, papain, and other serine/cysteine endopeptidases .

HY-N5183

Chymostatin C	Structural Classification Natural Products Microorganisms Source classification	Others
Chymostatin C is a subtype of chymostatin characterized by a leucine residue. Chymostatin inhibits chymotrypsin, papain, and other serine/cysteine endopeptidases .

HY-N5185

Cyclothiazomycin	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Fungal
Cyclothiazomycin selectively inhibits renin activity and does not inhibit pepsin, aspartic acid, serine, mercaptan protease and metalloproteinases. Cyclothiazomycin has weak antifungal activity .

HY-N4330

Rivulariapeptolides 1155	Natural Products Microorganisms Source classification	Ser/Thr Protease
Rivulariapeptolides 1155 is a potent serine protease inhibitor with IC₅₀s of 41.84, 4.94, 56.54 nM for chymotrypsin, elastase, prpteinase K, respectively .

HY-126034

3,4-Dichloroisocoumarin	Structural Classification Animals Source classification Coumarins Phenylpropanoids	Ser/Thr Protease Apoptosis
3,4-Dichloroisocoumarin is a potent *serine-protease* and SrLip inhibitor (K_i for SrLip: 26.6 μM). 3,4-Dichloroisocoumarin is opened by serine proteases and then undergoes acylation with the enzyme, thereby inhibiting protease activity. 3,4-Dichloroisocoumarin can induce DNA fragmentation and Apoptosis. 3,4-Dichloroisocoumarin can be used in the research of multiple fields such as tumors, cardiovascular disease and enzyme catalytic mechanisms .

HY-13434

Ionomycin Maximum Cited Publications 85 Publications Verification SQ23377	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Disease Research Anticancer Disease Research Fields Other Antibiotics	Calcium Channel PKC Bacterial Apoptosis Antibiotic
Ionomycin (SQ23377) is a potent, selective calcium ionophore and an antibiotic produced by Streptomyces conglobatus. Ionomycin (SQ23377) is highly specific for divalent cations (Ca>Mg>Sr=Ba). Ionomycin (SQ23377) promotes apoptosis. Ionomycin also induces the activation of protein kinase C (PKC) .

HY-N15009

Kynapcin-13	Structural Classification Natural Products Microorganisms Source classification	Prolyl Endopeptidase (PREP)
Kynapcin-13 can non-competitively inhibit the activity of prolyl endopeptidase (PEP) with an IC₅₀ of 76.80 μM. Kynapcin-13 has a little inhibitory effect on other serine proteases .

HY-N15010

Kynapcin-28	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Prolyl Endopeptidase (PREP)
Kynapcin-28 can non-competitively inhibit the activity of prolyl endopeptidase (PEP) with an IC₅₀ of 76.80 μM. Kynapcin-28 has a little inhibitory effect on other serine proteases .

HY-W010128

6-(Dimethylamino)purine 6-Dimethylaminopurine; 6-DMAP	Classification of Application Fields Other Diseases Disease Research Fields	CDK DNA/RNA Synthesis Apoptosis
6-(Dimethylamino) purine (6-Dimethylaminopurine) is a serine threonine protein kinase inhibitor. 6-(Dimethylamino) purine can inhibit prolactin induced expression of lactoprotein genes in rabbit mammary gland cells. 6-(Dimethylamino) purine can affect the maturation of mammalian oocytes. 6-(Dimethylamino) purine can lead to downregulation of genes related to cell proliferation and cell cycle progression, such as proliferating cell nuclear antigen, insulin-like gene 1, and serine protease inhibitor 2 genes, and induce apoptosis in lymphoma cells (apoptosis) .

HY-13434A

Ionomycin calcium Maximum Cited Publications 85 Publications Verification SQ23377 calcium	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Disease Research Anticancer Disease Research Fields Other Antibiotics	Calcium Channel PKC Bacterial Apoptosis Antibiotic
Ionomycin calcium (SQ23377 calcium) is a potent, selective calcium ionophore and an antibiotic produced by Streptomyces conglobatus. Ionomycin calcium (SQ23377 calcium) is highly specific for divalent cations (Ca>Mg>Sr=Ba). Ionomycin (SQ23377) promotes apoptosis. Ionomycin calcium (SQ23377 calcium) also induces the activation of protein kinase C (PKC) .

HY-13512

Camostat mesylate 35+ Cited Publications Camostat mesilate; FOY305; FOY-S980	Human Gut Microbiota Metabolites Source classification Endogenous metabolite	Ser/Thr Protease SARS-CoV
Camostat mesylate (Camostat mesilate) is an orally active, synthetic serine protease inhibitor for chronic pancreatitis. Camostat mesylate, an inhibitor of TMPRSS2, shows antiviral activity against SARS-CoV-2. Camostat mesylate also inhibits the activity of prostasin, trypsin, and matriptase .

HY-134222AR

N-Acetylserine (Standard)	Structural Classification Natural Products Source classification Endogenous metabolite	Endogenous Metabolite
N-Acetylserine (Standard) is the analytical standard of N-Acetylserine. This product is intended for research and analytical applications. N-Acetylserine (N-Acetyl-L-serine) can bind to CysB apoprotein. N-acetylserine is the physiological inducer of cysteine biosynthesis. N-Acetylserine can stimulate in vitro cysJIH transcription .

HY-N1996

Chebulagic acid 4 Publications Verification	Structural Classification Classification of Application Fields Combretaceae Source classification Phenols Polyphenols Terminalia chebula Retz. Plants Inflammation/Immunology Disease Research Fields	COX Lipoxygenase SARS-CoV Influenza Virus
Chebulagic acid is a COX-LOX dual inhibitor isolated from the fruits of Terminalia chebula Retz, on angiogenesis. Chebulagic acid is a *M2 serine* to asparagine 31 mutation (S31N) inhibitor and influenza antiviral. Chebulagic acid also against SARS-CoV-2 viral replication with an EC₅₀** of 9.76 μM.

HY-13512R

Camostat mesylate (Standard) Camostat mesilate (Standard); FOY305 (Standard); FOY-S980 (Standard)	Human Gut Microbiota Metabolites Microorganisms Source classification Endogenous metabolite	Reference Standards Ser/Thr Protease SARS-CoV
Camostat (mesylate) (Standard) is the analytical standard of Camostat (mesylate). This product is intended for research and analytical applications. Camostat mesylate (Camostat mesilate) is an orally active, synthetic serine protease inhibitor for chronic pancreatitis. Camostat mesylate, an inhibitor of TMPRSS2, shows antiviral activity against SARS-CoV-2. Camostat mesylate also inhibits the activity of prostasin, trypsin, and matriptase .

HY-N1996R

Chebulagic acid (Standard)	Structural Classification Combretaceae Source classification Phenols Polyphenols Terminalia chebula Retz. Plants	Reference Standards COX Lipoxygenase SARS-CoV Influenza Virus
Chebulagic acid (Standard) is the analytical standard of Chebulagic acid. This product is intended for research and analytical applications. Chebulagic acid is a COX-LOX dual inhibitor isolated from the fruits of Terminalia chebula Retz, on angiogenesis. Chebulagic acid is a M2 serine to asparagine 31 mutation (S31N) inhibitor and influenza antiviral. Chebulagic acid also against SARS-CoV-2 viral replication with an EC₅₀ of 9.76 μM.

HY-N6798

Myriocin 5+ Cited Publications Thermozymocidin; ISP-I	Infection Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields	HCV Antibiotic
Myriocin (Thermozymocidin), a fungal metabolite could be isolated from Myriococcum albomyces, Isaria sinclairi and Mycelia sterilia, is a potent inhibitor of serine-palmitoyl-transferase (SPT) and a key enzyme in de novo synthesis of sphingolipids. Myriocin suppresses replication of both the subgenomic HCV-1b replicon and the JFH-1 strain of genotype 2a infectious HCV, with an IC₅₀ of 3.5 μg/mL for inhibiting HCV infection .

HY-N6798R

Myriocin (Standard) Thermozymocidin (Standard); ISP-I (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Reference Standards HCV Antibiotic
Myriocin (Standard) is the analytical standard of Myriocin. This product is intended for research and analytical applications. Myriocin (Thermozymocidin), a fungal metabolite could be isolated from Myriococcum albomyces, Isaria sinclairi and Mycelia sterilia, is a potent inhibitor of serine-palmitoyl-transferase (SPT) and a key enzyme in de novo synthesis of sphingolipids. Myriocin suppresses replication of both the subgenomic HCV-1b replicon and the JFH-1 strain of genotype 2a infectious HCV, with an IC50 of 3.5 μg/mL for inhibiting HCV infection[1][2][3].

HY-I1070

D-Isoleucine (R)-Isoleucine	Microorganisms Source classification	ASCT
D-Isoleucine is a selective competitive activator of the Asc-1 antiporter (Ki=0.98 mM). D-Isoleucine promotes the release of D-serine and glycine by binding to the Asc-1 protein on the neuronal cell membrane, and enhances NMDA receptor-dependent synaptic plasticity. D-Isoleucine can be used in the study of neurodegenerative diseases (such as Alzheimer's disease and schizophrenia). D-Isoleucine also acts as a non-classical D-amino acid, interferes with bacterial peptidoglycan synthesis, and inhibits the formation of Staphylococcus aureus biofilm, and has potential antibacterial application value[1][2].

HY-111355B

Cholesteryl sulfate sodium	Structural Classification Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite
Cholesteryl sulfate sodium is an orally available, NPC2-targeted cholesterol biosynthesis agonist. Cholesteryl sulfate sodium activates SREBP2 by competitively binding to NPC2, promoting cholesterol synthesis (EC₅₀=50 μM). Cholesteryl sulfate sodium enhances the self-assembly ability of Mitoxantrone hydrochloride (HY-13502A), while repairing the intestinal mucosal barrier and inhibiting inflammation by regulating serine protease activity and PKCη signaling pathway. Cholesteryl sulfate sodium is a component of the platelet cell membrane and supports platelet adhesion. Cholesteryl sulfate sodium also regulates the activity of selective protein kinase C isoforms and modulates the specificity of PI3K, playing a role in keratinocyte differentiation .

Cat. No.	Product Name	Chemical Structure

HY-N0650S11

*L-Serine-d7*
L-Serine-d₇ is the deuterium labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-N0650S8

*L-Serine-d3* 2 Publications Verification
L-Serine-d₃ is the deuterium labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-N0650S1

*L-Serine-13C*
L-Serine- ¹³C is the ¹³C-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-N0650S10

*L-Serine-15N*
L-Serine- ¹⁵N is the ¹⁵N-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-N0650S2

*L-Serine-1-13C*
L-Serine-1- ¹³C is the ¹³C-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-101491S

SR-18292-d9
SR-18292-d₉ is the deuterium labeled SR-18292 (HY-101491). SR-18292 is a PPAR gamma coactivator-1α (PGC-1α) inhibitor, which increases PGC-1α acetylation, suppresses gluconeogenic gene expression and reduces glucose production in hepatocytes .

HY-169898S

SR 144528-d3
SR 144528-d₃ is deuterium labeled SR 144528 .

HY-N0650S7

*L-Serine-d2*
L-Serine-d₂ is the deuterium labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-N0650S4

*L-Serine-2-13C*
L-Serine-2- ¹³C is the ¹³C-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-W718796

*DL-Serine-15N*
DL-Serine- ¹⁵N is ¹⁵N-labeled DL-Serine (HY-Y0507) DL-Serine, a fundamental metabolite, is a mixture of D-Serine and L-Serine. DL-Serine has antiviral activity against the multiplication of tobacco mosaic virus (TMV).

HY-N0650S

*L-Serine-13C3*
L-Serine- ¹³C₃ is the ¹³C-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-100808S

D-Serine-d3

D-Serine-d₃ ((R)-Serine-d₃) is a deuterium labeled D-Serine (HY-100808). D-Serine ((R)-Serine), an endogenous amino acid involved in glia-synapse interactions that has unique neurotransmitter characteristics, is a potent co-agonist at the NMDA glutamate receptor. D-Serinee has a cardinal modulatory role in major NMDAR-dependent processes including NMDAR-mediated neurotransmission, neurotoxicity, synaptic plasticity, and cell migration .

HY-B0209S

Metolazone-d7
Metolazone-d₇ is deuterium labeled Metolazone. Metolazone (SR-720-22) is primarily used to treat congestive heart failure and high blood pressure.

HY-N0650S9

*L-Serine-15N,d3*
L-Serine- ¹⁵N,d₃ is the deuterium and ¹⁵N-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-N0650S6

*L-Serine1-13C,15N*
L-Serine1- ¹³C, ¹⁵N is the ¹³C- and ¹⁵N-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-Y0507S

*DL-Serine-2,3,3-d3*
DL-Serine-2,3,3-d₃ is the deuterium labeled DL-Serine. DL-Serine, a fundamental metabolite, is a mixture of D-Serine and L-Serine. DL-Serine has antiviral activity against the multiplication of tobacco mosaic virus (TMV) .

HY-N0650S12

*L-Serine-d3,15n*
L-Serine- ¹⁵N,d₃ is the deuterium and ¹⁵N labeled L-Serine[1]. L-Serine ((-)-Serine;(S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation[2].

HY-N0650S5

*L-Serine-13C3,15N*
L-Serine- ¹³C₃, ¹⁵N is the ¹³C- and ¹⁵N-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-W754474

*N-Palmitoyl-O-phosphocholine Serine-d9*
N-Palmitoyl-O-phosphocholine Serine-d₉ is the deuterium labeled N-Palmitoyl-O-phosphocholine Serine (HY-W754473).

HY-W747757

*N-Arachidonoyl-L-serine-d8*
N-Arachidonoyl-L-serine-d₈ is deuterium labeled N-Arachidonoyl-L-serine .

HY-14136S

Rimonabant-d10
Rimonabant-d₁₀ is deuterium labeled Rimonabant. Rimonabant (SR141716) is a highly potent, brain penetrated and selective central cannabinoid receptor (CB1) antagonist with a Ki of 1.8 nM. Rimonabant (SR141716) also inhibits Mycobacterial membrane protein Large 3 (MMPL3).

HY-N0650S3

*L-Serine-13C3,15N,d3*
L-Serine- ¹³C₃, ¹⁵N,d₃ is the deuterium, ¹³C-, and 15-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-W751156

O-Phospho-L-serine-13C3

O-Phospho-L-serine- ¹³C₃ (L-Serine O-phosphate- ¹³C₃) is the ¹³C-labeled O-Phospho-L-serine (HY-15129). O-Phospho-L-serine is the immediate precursor to L-cystein in the serine synthesis pathway, and an agonist at the group III mGluR receptors (mGluR4, mGluR6, mGluR7, and mGluR8); O-Phospho-L-serine also acts as a weak antagonist for mGluR1 and a potent antagonist for mGluR2 .

HY-W750898

*N-(4-Nitrobenzoyl)-D-serine-d3 Quinine Salt*
N-(4-Nitrobenzoyl)-D-serine-d₃ Quinine Salt is the deuterium labeled N-(4-Nitrobenzoyl)-D-serine Quinine Salt.

HY-A0016S3

Dronedarone-d6

Dronedarone-d₆ (SR 33589-d₆) is deuterium labeled Dronedarone. Dronedarone (SR 33589), a derivative of amiodarone (HY-14187), is a class III antiarrhythmic agent for the study of atrial fibrillation (AF) and atrial flutter. Dronedarone is a potent blocker of multiple ion currents, including potassium current, sodium current, and L-type calcium current, and exhibits antiadrenergic effects by noncompetitive binding to β-adrenergic receptors. Dronedarone is a substrate for and a moderate inhibitor of CYP3A4 .

HY-15129S

*O-Phospho-L-serine-13C3,15N*
O-Phospho-L-serine- ¹³C₃, ¹⁵N is the ¹³C- and ¹⁵N-labeled O-Phospho-L-serine. O-Phospho-L-serine is the immediate precursor to L-serine in the serine synthesis pathway, and an agonist at the group III mGluR receptors (mGluR4, mGluR6, mGluR7, and mGluR8); O-Phospho-L-serine also acts as a weak antagonist for mGluR1 and a potent antagonist for mGluR2 .

HY-32207S

Serine Hydrolase inhibitor-1-pip-2-nitropyridine-d4
Serine Hydrolase inhibitor-1-pip-2-nitropyridine-d₄ is the deuterium labeled Serine Hydrolase inhibitor-1-pip-2-nitropyridine .

HY-B0202S3

Irbesartan-d7
Irbesartan-d₇ is deuterated labeled Irbesartan (HY-B0202). Irbesartan (SR-47436) is an orally active Ang II type 1 (AT1) receptor blocker (ARB). Irbesartan can relax the blood vessels, low blood pressure and increase the supply of blood and oxygen to the heart. Irbesartan can be used for the research of high blood pressure, heart failure, and diabetic kidney disease .

HY-B0202AS

Irbesartan-d7 hydrochloride

Irbesartan-d₇ hydrochloride is deuterated labeled Irbesartan hydrochloride (HY-B0202A). Irbesartan (SR-47436) hydrochloride is an orally active Ang II type 1 (AT1) receptor blocker (ARB). Irbesartan hydrochloride can relax the blood vessels, low blood pressure and increase the supply of blood and oxygen to the heart. Irbesartan hydrochloride can be used for the research of high blood pressure, heart failure, and diabetic kidney disease .

HY-B0202S4

Irbesartan-13C,d4
Irbesartan- ¹³C,d₄ (SR-47436- ¹³C,d₄; BMS-186295- ¹³C,d₄) is ¹³C-labeled Irbesartan (HY-B0202) .

HY-146865S

*1-Heptadecanoyl-2-hydroxy-sn-glycero-3-phospho-L-serine-d5 sodium*
1-Heptadecanoyl-2-hydroxy-sn-glycero-3-phospho-L-serine-d₅ (sodium) is deuterium labeled 1-Heptadecanoyl-2-hydroxy-sn-glycero-3-phospho-L-serine (sodium).

HY-146861S

*1-Pentadecanoyl-2-hydroxy-sn-glycero-3-phospho-L-serine-d5 sodium*
1-Pentadecanoyl-2-hydroxy-sn-glycero-3-phospho-L-serine-d₅ (sodium) is deuterium labeled 1-Pentadecanoyl-2-hydroxy-sn-glycero-3-phospho-L-serine (sodium).

HY-146820S

*1-Pentadecanoyl-2-oleoyl-sn-glycero-3-phospho-L-serine-d7 sodium*
1-Pentadecanoyl-2-oleoyl-sn-glycero-3-phospho-L-serine-d₇ (sodium) is deuterium labeled 1-Pentadecanoyl-2-oleoyl-sn-glycero-3-phospho-L-serine (sodium).

HY-146864S

*1-Nonadecanoyl-2-hydroxy-sn-glycero-3-phospho-L-serine-d5 sodium*
1-Nonadecanoyl-2-hydroxy-sn-glycero-3-phospho-L-serine-d₅ (sodium) is deuterium labeled 1-Nonadecanoyl-2-hydroxy-sn-glycero-3-phospho-L-serine (sodium).

HY-146866S

*1-Heptadecanoyl-2-docosatetraenoyl-sn-glycero-3-phospho- L-serine-d5 sodium*
1-Heptadecanoyl-2-docosatetraenoyl-sn-glycero-3-phospho- L-serine-d₅ (sodium) is deuterium labeled 1-Heptadecanoyl-2-docosatetraenoyl-sn-glycero-3-phospho- L-serine (sodium).

HY-146869S

*1-Heptadecanoyl-2-palmitoleoyl-sn-glycero-3-phospho- L-serine-d5 sodium*
1-Heptadecanoyl-2-palmitoleoyl-sn-glycero-3-phospho- L-serine-d₅ (sodium) is deuterium labeled 1-Heptadecanoyl-2-palmitoleoyl-sn-glycero-3-phospho- L-serine (sodium).

HY-146870S

*1-Heptadecanoyl-2-myristoleoyl-sn-glycero-3-phospho- L-serine-d5 sodium*
1-Heptadecanoyl-2-myristoleoyl-sn-glycero-3-phospho- L-serine-d₅ (sodium) is deuterium labeled 1-Heptadecanoyl-2-myristoleoyl-sn-glycero-3-phospho- L-serine (sodium).

HY-146867S

*1-Heptadecanoyl-2-eicosatrienoyl-sn-glycero-3-phospho- L-serine-d5 sodium*
1-Heptadecanoyl-2-eicosatrienoyl-sn-glycero-3-phospho- L-serine-d₅ (sodium) is deuterium labeled 1-Heptadecanoyl-2-eicosatrienoyl-sn-glycero-3-phospho- L-serine (sodium).

HY-146868S

*1-Heptadecanoyl-2-oleoyl-sn-glycero-3-phospho- L-serine-d5 sodium*
1-Heptadecanoyl-2-oleoyl-sn-glycero-3-phospho- L-serine-d₅ (sodium) is deuterium labeled 1-Heptadecanoyl-2-oleoyl-sn-glycero-3-phospho- L-serine (sodium).

HY-12753AS

Debutyldronedarone-d7 hydrochloride

Debutyldronedarone-d₇ hydrochloride is deuterated labeled Debutyldronedarone hydrochloride (HY-12753A). Debutyldronedarone (SR35021) hydrochloride, the main metabolite of Dronedarone, is a selective thyroid hormone receptor α₁ (TRα₁) inhibitor. Debutyldronedarone hydrochloride inhibits T3 binding to TRα₁ and TRβ₁ by 77% and 25%, respectively. Debutyldronedarone hydrochloride can be used for the research of arrhythmic .

HY-115435S

*1,2-Dimyristoyl-sn-glycero-3-phospho-L-serine-d54 sodium*
1,2-Dimyristoyl-sn-glycero-3-phospho-L-serine-d₅₄ (sodium) is deuterium labeled 1,2-Dimyristoyl-sn-glycero-3-phospho-L-serine.

HY-W727757

Pristanic acid-d6 (>90%)
Pristanic acid-d₆ (>90%) is the deuterium labeled Pristanic acid (HY-113024). Pristanic acid is an endogenous metabolite present in Blood that can be used for the research of Alpha Methylacyl CoA Racemase Deficiency and Zellweger Syndrome .

HY-113024S

Pristanic acid-d3
Pristanic acid-d₃ is deuterium labeled Pristanic acid. Pristanic acid is an endogenous metabolite present in Blood that can be used for the research of Alpha Methylacyl CoA Racemase Deficiency and Zellweger Syndrome .

HY-167592S

17:0-20:3 PS-d5
17:0-20:3 PS-d₅ (1-Heptadecanoyl-2-eicosatrienoyl-sn-glycero(d₅)-3-phospho- L-serine (sodium)) is deuterium labeled 17:0-20:3 PS .

HY-113067S

Phytanic acid-d3
Phytanic acid-d₃ is the deuterium labeled Phytanic acid . Phytanic acid is an endogenous metabolite present in Blood that can be used for the research of Zellweger Syndrome, Alpha Methylacyl CoA Racemase Deficiency, Rhizomelic Chondrodysplasia Punctata and Infantile Refsum Disease .

HY-14137S

Rimonabant-d10 hydrochloride
Rimonabant-d₁₀ (hydrochloride) is the deuterium labeled Rimonabant hydrochloride. Rimonabant hydrochloride (SR 141716A hydrochloride) is a highly potent and selective central cannabinoid receptor (CB1) antagonist with an K_i of 1.8 nM. Rimonabant hHydrochloride (SR 141716A Hydrochloride) also inhibits Mycobacterial membrane protein Large 3 (MMPL3) .

HY-B0202S2

Irbesartan-d6-1
Irbesartan-d₆-1 is the deuterium labeled Irbesartan . Irbesartan (SR-47436) is an orally active Ang II type 1 (AT1) receptor blocker (ARB). Irbesartan can relax the blood vessels, low blood pressure and increase the supply of blood and oxygen to the heart. Irbesartan can be used for the research of high blood pressure, heart failure, and diabetic kidney disease .

HY-12753S

Debutyldronedarone-d7
Debutyldronedarone-d₇ is deuterium labeled Debutyldronedarone. Debutyldronedarone is a major circulating active metabolite of dronedarone (HY-A0016) in humans.Debutyldronedarone exhibits a potency that is 1/10 to 1/3 of that of the parent agent .

HY-12753S1

Debutyldronedarone-d6 hydrochloride
Debutyldronedarone-d₆ (hydrochloride) is deuterium labeled Debutyldronedarone. Debutyldronedarone is a major circulating active metabolite of dronedarone (HY-A0016) in humans. Debutyldronedarone exhibits a potency that is 1/10 to 1/3 of that of the parent agent .

HY-W007941S1

Fmoc-Ser(tBu)-OH-15N
Fmoc-Ser(tBu)-OH- ¹⁵N is the ¹⁵N labeled Fmoc-Ser(tBu)-OH . Fmoc-Ser(tBu)-OH is a serine derivative .

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