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  5. MYO3A Protein, Human (Active, sf9, His, GST, Strep)

MYO3A Protein, Human (Active, sf9, His, GST, Strep)

Cat. No.: HY-P703323
Handling Instructions Technical Support

MYO3A Protein, Human (Active, sf9, His, GST, Strep) is the recombinant human-derived MYO3A, expressed by sf9 insect cells , with Strep, His, GST labeled tag. ,

For research use only. We do not sell to patients.

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Description

MYO3A Protein, Human (Active, sf9, His, GST, Strep) is the recombinant human-derived MYO3A, expressed by sf9 insect cells , with Strep, His, GST labeled tag. ,
Background

MYO3A is an actin-dependent motor protein with protein kinase activity, playing a crucial role in hearing. It likely also contributes to vision and is essential for normal cochlear hair bundle development and auditory function. This protein is involved in the early stages of cochlear hair bundle morphogenesis, influencing the number and length of stereocilia while restricting microvilli growth within developing auditory hair bundles, thereby shaping their staircase-like architecture. Additionally, MYO3A facilitates actin elongation at stereocilia tips by transporting the actin regulatory factor ESPN to the plus ends of actin filaments. by similar: Its functions are closely tied to actin dynamics and the precise structural regulation of auditory hair bundles.
Species

Human
Source

Sf9 insect cells
Tag

Strep;His;GST
Accession

Q8NEV4-1 (M1-G434)
Gene ID

53904
Protein Length

Partial
Synonyms
Myosin-IIIa; MYO3A; Homo sapiens; Human; Actin-binding; Kinase; Motor protein; Myosin; Serine/threonine-protein kinase; Transferase; 2.7.11.1
Predicted Molecular Mass
77.8 kDa
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

MYO3A Protein, Human (Active, sf9, His, GST, Strep) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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