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Prasterone sulfate sodium-d<sub>6</sub>

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-141921S
    Dehydroepiandrosterone sulfate sodium-d6

    DHEA sulfate sodium-d<sub>6sub>; Prasterone sulfate sodium-d<sub>6sub>

    		 Isotope-Labeled Compounds GABA Receptor Sigma Receptor iGluR PPAR NF-κB Neurological Disease Metabolic Disease Inflammation/Immunology
    Dehydroepiandrosterone sulfate sodium salt-d6 (DHEA sulfate sodium salt-d6; Prasterone sulfate sodium salt-d6) is the deuterium labeled Dehydroepiandrosterone sulfate sodium salt (HY-B0765). Dehydroepiandrosterone sulfate (DHEA sulfate; Prasterone sulfate) sodium salt is a neurosteroid and the main secretion product of the adrenal gland. Dehydroepiandrosterone sulfate sodium salt has both non-competitive antagonist activity of GABAA receptor and agonist activity of σ1 receptor. Dehydroepiandrosterone sulfate sodium salt can partially penetrate the blood-brain barrier, inhibit GABAA receptor-mediated chloride influx, enhance NMDA receptor activity through σ1 receptors, exert anti-inflammatory, anti-glucocorticoid and antidepressant effects, and increase convulsive sensitivity. Dehydroepiandrosterone sulfate sodium salt participates in neuroprotection, neurite growth regulation and catecholamine secretion regulation, and can be used in the study of depression, post-traumatic stress disorder (PTSD), Alzheimer's disease, etc. Dehydroepiandrosterone sulfate sodium salt may also be a biomarker for cardiovascular disease mortality, and its concentration is independently and negatively correlated with mortality .
    Dehydroepiandrosterone sulfate sodium-d6
  • HY-113416AS
    Dehydroepiandrosterone sulfate-d6 sodium dihydrate

    DHEA sulfate-d<sub>6sub> sodium dihydrate; Prasterone sulfate-d<sub>6sub> sodium dihydrate

    		 Isotope-Labeled Compounds GABA Receptor Sigma Receptor iGluR PPAR NF-κB Neurological Disease Metabolic Disease Inflammation/Immunology
    Dehydroepiandrosterone sulfate sodium dihydrate-d6 sodium dihydrate is the deuterium labeled Dehydroepiandrosterone sulfate sodium dihydrate. Dehydroepiandrosterone sulfate (DHEA sulfate; Prasterone sulfate) sodium dihydrate is a neurosteroid and the main secretion product of the adrenal gland. Dehydroepiandrosterone sulfate sodium dihydrate has both non-competitive antagonist activity of GABAA receptor and agonist activity of σ1 receptor. Dehydroepiandrosterone sulfate sodium dihydrate can partially penetrate the blood-brain barrier, inhibit GABAA receptor-mediated chloride influx, enhance NMDA receptor activity through σ1 receptors, exert anti-inflammatory, anti-glucocorticoid and antidepressant effects, and increase convulsive sensitivity. Dehydroepiandrosterone sulfate sodium dihydrate participates in neuroprotection, neurite growth regulation and catecholamine secretion regulation, and can be used in the study of depression, post-traumatic stress disorder (PTSD), Alzheimer's disease, etc. Dehydroepiandrosterone sulfate sodium dihydrate may also be a biomarker for cardiovascular disease mortality, and its concentration is independently and negatively correlated with mortality .
    Dehydroepiandrosterone sulfate-d6 sodium dihydrate
  • HY-113416R
    Dehydroepiandrosterone sulfate (Standard)

    DHEA sulfate (Standard); Prasterone sulfate (Standard)

    		 Reference Standards GABA Receptor Sigma Receptor iGluR PPAR NF-κB Neurological Disease Metabolic Disease Inflammation/Immunology
    Dehydroepiandrosterone sulfate (DHEA sulfate; Prasterone sulfate) (Standard) is the analytical standard of Dehydroepiandrosterone sulfate (HY-113416). This product is intended for research and analytical applications. Dehydroepiandrosterone sulfate (DHEA sulfate; Prasterone sulfate) is a neurosteroid and the main secretion product of the adrenal gland. Dehydroepiandrosterone sulfate has both non-competitive antagonist activity of GABAA receptor and agonist activity of σ1 receptor. Dehydroepiandrosterone sulfate can partially penetrate the blood-brain barrier, inhibit GABAA receptor-mediated chloride influx, enhance NMDA receptor activity through σ1 receptors, exert anti-inflammatory, anti-glucocorticoid and antidepressant effects, and increase convulsive sensitivity. Dehydroepiandrosterone sulfate participates in neuroprotection, neurite growth regulation and catecholamine secretion regulation, and can be used in the study of depression, post-traumatic stress disorder (PTSD), Alzheimer's disease, etc. Dehydroepiandrosterone sulfate may also be a biomarker for cardiovascular disease mortality, and its concentration is independently and negatively correlated with mortality .
    Dehydroepiandrosterone sulfate (Standard)
  • HY-B0765
    Dehydroepiandrosterone sulfate sodium
    5 Publications Verification

    DHEA sulfate sodium; Prasterone sulfate sodium

    		 GABA Receptor Sigma Receptor iGluR PPAR NF-κB Neurological Disease Metabolic Disease Inflammation/Immunology
    Dehydroepiandrosterone sulfate (DHEA sulfate; Prasterone sulfate) sodium salt is a neurosteroid and the main secretion product of the adrenal gland. Dehydroepiandrosterone sulfate sodium salt has both non-competitive antagonist activity of GABAA receptor and agonist activity of σ1 receptor. Dehydroepiandrosterone sulfate sodium salt can partially penetrate the blood-brain barrier, inhibit GABAA receptor-mediated chloride influx, enhance NMDA receptor activity through σ1 receptors, exert anti-inflammatory, anti-glucocorticoid and antidepressant effects, and increase convulsive sensitivity. Dehydroepiandrosterone sulfate sodium salt participates in neuroprotection, neurite growth regulation and catecholamine secretion regulation, and can be used in the study of depression, post-traumatic stress disorder (PTSD), Alzheimer's disease, etc. Dehydroepiandrosterone sulfate sodium salt may also be a biomarker for cardiovascular disease mortality, and its concentration is independently and negatively correlated with mortality .
    Dehydroepiandrosterone sulfate sodium
  • HY-113416
    Dehydroepiandrosterone sulfate
    5 Publications Verification

    DHEA sulfate; Prasterone sulfate

    		 GABA Receptor Sigma Receptor iGluR PPAR NF-κB Neurological Disease Metabolic Disease Inflammation/Immunology
    Dehydroepiandrosterone sulfate (DHEA sulfate; Prasterone sulfate) is a neurosteroid and the main secretion product of the adrenal gland. Dehydroepiandrosterone sulfate has both non-competitive antagonist activity of GABAA receptor and agonist activity of σ1 receptor. Dehydroepiandrosterone sulfate can partially penetrate the blood-brain barrier, inhibit GABAA receptor-mediated chloride influx, enhance NMDA receptor activity through σ1 receptors, exert anti-inflammatory, anti-glucocorticoid and antidepressant effects, and increase convulsive sensitivity. Dehydroepiandrosterone sulfate participates in neuroprotection, neurite growth regulation and catecholamine secretion regulation, and can be used in the study of depression, post-traumatic stress disorder (PTSD), Alzheimer's disease, etc. Dehydroepiandrosterone sulfate may also be a biomarker for cardiovascular disease mortality, and its concentration is independently and negatively correlated with mortality .
    Dehydroepiandrosterone sulfate
  • HY-111355S
    Cholesterol sulfate-d7 sodium

    		Isotope-Labeled Compounds Others
    Cholesterol sulfate sodium-d7 is the deuterium labeled Cholesterol sulfate sodium .
    Cholesterol sulfate-d7 sodium
  • HY-N0488S2
    Vincristine-d6 sulfate

    Leurocristine-d<sub>6sub> sulfate; NSC-67574-d<sub>6sub> sulfate; 22-Oxovincaleukoblastine-d<sub>6sub> sulfate

    		 Isotope-Labeled Compounds Microtubule/Tubulin Apoptosis Cancer
    Vincristine-d6 (sulfate) is the deuterium labeled Vincristine sulfate. Vincristine sulfate is an antitumor vinca alkaloid which inhibits microtubule formation in mitotic spindle, resulting in an arrest of dividing cells at the metaphase stage. It binds to microtubule with a Ki of 85 nM.
    Vincristine-d6 sulfate
  • HY-B0765R
    Dehydroepiandrosterone sulfate sodium (Standard)

    DHEA sulfate sodium (Standard); Prasterone sulfate sodium (Standard)

    		 Reference Standards GABA Receptor Sigma Receptor iGluR PPAR NF-κB Neurological Disease Metabolic Disease Inflammation/Immunology
    Dehydroepiandrosterone sulfate (DHEA sulfate; Prasterone sulfate) sodium salt (Standard) is the analytical standard of Dehydroepiandrosterone sulfate sodium salt (HY-B0765). This product is intended for research and analytical applications. Dehydroepiandrosterone sulfate (DHEA sulfate; Prasterone sulfate) is a neurosteroid and the main secretion product of the adrenal gland. Dehydroepiandrosterone sulfate has both non-competitive antagonist activity of GABAA receptor and agonist activity of σ1 receptor. Dehydroepiandrosterone sulfate can partially penetrate the blood-brain barrier, inhibit GABAA receptor-mediated chloride influx, enhance NMDA receptor activity through σ1 receptors, exert anti-inflammatory, anti-glucocorticoid and antidepressant effects, and increase convulsive sensitivity. Dehydroepiandrosterone sulfate participates in neuroprotection, neurite growth regulation and catecholamine secretion regulation, and can be used in the study of depression, post-traumatic stress disorder (PTSD), Alzheimer's disease, etc. Dehydroepiandrosterone sulfate may also be a biomarker for cardiovascular disease mortality, and its concentration is independently and negatively correlated with mortality .
    Dehydroepiandrosterone sulfate sodium (Standard)
  • HY-141901S1
    DHEA-d5

    Prasterone-d<sub>5<sub>; Dehydroisoandrosterone-d<sub>5<sub>; Dehydroepiandrosterone-d<sub>5<sub>

    		 Isotope-Labeled Compounds Endogenous Metabolite Androgen Receptor Cardiovascular Disease Endocrinology Cancer
    DHEA-d5 (Prasterone-d5; Dehydroisoandrosterone-d5; Dehydroepiandrosterone-d5) is the deuterium labeled DHEA (HY-14650). DHEA (Prasterone) is one of the most abundant steroid hormones. DHEA (Prasterone) mediates its action via multiple signaling pathways involving specific membrane receptors and via transformation into androgen and estrogen derivatives (e.g., androgens, estrogens, 7α and 7β DHEA, and 7α and 7β epiandrosterone derivatives) acting through their specific receptors.
    DHEA-d5
  • HY-W743264
    17β-Estradiol sulfate-d3 sodium

    17β-Estradiol 3-sulfate-d<sub>6sub> sodium

    		 Isotope-Labeled Compounds GABA Receptor Neurological Disease
    17β-Estradiol sulfate-d3 sodium (17β-Estradiol 3-sulfate-d3 sodium) is the deuterium labeled 17β-Estradiol sulfate sodium (HY-141672). 17β-Estradiol sulfate sodium, also known as β-Estradiol 3-sulfate sodium salt, is a neuroactive steroid .
    17β-Estradiol sulfate-d3 sodium
  • HY-RS13999
    SUB1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    SUB1 Human Pre-designed siRNA Set A contains three designed siRNAs for SUB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    SUB1 Human Pre-designed siRNA Set A
    SUB1 Human Pre-designed siRNA Set A
  • HY-RS18793
    Sub1 Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Sub1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Sub1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Sub1 Mouse Pre-designed siRNA Set A
    Sub1 Mouse Pre-designed siRNA Set A
  • HY-RS25282
    Sub1 Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Sub1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Sub1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Sub1 Rat Pre-designed siRNA Set A
    Sub1 Rat Pre-designed siRNA Set A
  • HY-146227
    DNA topoisomerase II inhibitor 1

    		Topoisomerase Apoptosis Cancer
    DNA topoisomerase II inhibitor 1 (compound 8ed) is a potent DNA topoisomerase II inhibitor. DNA topoisomerase II inhibitor 1 shows anti-proliferative activity. DNA topoisomerase II inhibitor 1 induces apoptosis and cell cycle arrest at sub G1 phase .
    DNA topoisomerase II inhibitor 1
  • HY-N0488S1
    Vincristine-d3-ester sulfate

    Leurocristine-d<sub>3sub>-ester sulfate; NSC-67574-d<sub>3sub>-ester sulfate; 22-Oxovincaleukoblastine-d<sub>3sub>-ester sulfate

    		 Microtubule/Tubulin Apoptosis Cancer
    Vincristine-d3-ester (sulfate) is the deuterium labeled Vincristine sulfate. Vincristine sulfate is an antitumor vinca alkaloid which inhibits microtubule formation in mitotic spindle, resulting in an arrest of dividing cells at the metaphase stage. It binds to microtubule with a Ki of 85 nM .
    Vincristine-d3-ester sulfate
  • HY-N0488S
    Vincristine-d3 sulfate

    Leurocristine-d<sub>3sub> sulfate; NSC-67574-d<sub>3sub> sulfate; 22-Oxovincaleukoblastine-d<sub>3sub> sulfate

    		 Isotope-Labeled Compounds Microtubule/Tubulin Apoptosis Cancer
    Vincristine-d3 (sulfate)is the deuterium labeled Vincristine sulfate. Vincristine sulfate is an antitumor vinca alkaloid which inhibits microtubule formation in mitotic spindle, resulting in an arrest of dividing cells at the metaphase stage. It binds to microtubule with a Ki of 85 nM .
    Vincristine-d3 sulfate
  • HY-B1370S
    Hydroxychloroquine-d4 sulfate

    HCQ-d<sub>4sub> sulfate

    		 Isotope-Labeled Compounds Parasite Toll-like Receptor (TLR) SARS-CoV Autophagy Infection Cancer
    Hydroxychloroquine-d4 (sulfate) is the deuterium labeled Hydroxychloroquine sulfate. Hydroxychloroquine sulfate (HCQ sulfate) is a synthetic antimalarial agent which can also inhibit Toll-like receptor 7/9 (TLR7/9) signaling. Hydroxychloroquine sulfate is efficiently inhibits SARS-CoV-2 infection in vitro .
    Hydroxychloroquine-d4 sulfate
  • HY-B1134AS
    Imazalil-d5 sulfate

    Enilconazolel-d<sub>5sub> sulfate

    		 Fungal Isotope-Labeled Compounds Others
    Imazalil-d5 (sulfate) is the deuterium labeled Imazalil sulfate .
    Imazalil-d5 sulfate
  • HY-15283AS
    (±)-Clopidogrel-d7 sulfate

    (±)-Clopidogrelum-d<sub>7sub> sulfate

    		 P2Y Receptor Isotope-Labeled Compounds Others
    (±)-Clopidogrel-d7 (sulfate) is the deuterium labeled (±)-Clopidogrel sulfate .
    (±)-Clopidogrel-d7 sulfate
  • HY-W743292
    Phenethicillin sodium-d5

    Pheneticillin sodium-d<sub>5sub>; α-Phenoxyethylpenicillin sodium-d<sub>5sub>

    		 Isotope-Labeled Compounds Bacterial Infection
    Phenethicillin sodium-d5 (Pheneticillin sodium-d5; α-Phenoxyethylpenicillin sodium-d5) is the deuterium labeled Phenethicillin sodium (HY-137945). Phenethicillin (α-Phenoxyethylpenicillin) sodium is a Penicillin, and has antimicrobial activity .
    Phenethicillin sodium-d5
  • HY-W654121
    p-Cresol sulfate-d4 potassium

    p-Tolyl sulfate-d<sub>4sub> potassium

    		 Isotope-Labeled Compounds Endogenous Metabolite p38 MAPK JNK Inflammation/Immunology
    p-Cresol sulfate-d4 (potassium) is deuterium labeled p-Cresyl sulfate (potassium). p-Cresyl sulfate potassium is a uremic toxin that binds to a prototype protein. p-Cresyl sulfate potassium activates the JNK and p38 MAPK signaling pathways. p-Cresyl sulfate potassium has pro-inflammatory activity .
    p-Cresol sulfate-d4 potassium
  • HY-111431AS
    p-Cresol sulfate-d7 potassium

    p-Tolyl sulfate-d<sub>7sub> (potassium)

    		 Endogenous Metabolite Metabolic Disease
    p-Cresol sulfate-d7 (potassium) is the deuterium labeled p-Cresyl sulfate potassium. p-Methylphenyl potassium sulfate is a prototype protein-bound uremic toxin[1][2].
    p-Cresol sulfate-d7 potassium
  • HY-141672S1
    17β-Estradiol sulfate-d4 sodium

    17β-Estradiol 3-sulfate-d<sub>4sub> sodium

    		 GABA Receptor Neurological Disease
    17β-Estradiol sulfate-d4 (sodium) is the deuterium labeled 17β-Estradiol sulfate 17β-Estradiol sulfate (sodium), also known as β-Estradiol 3-sulfate sodium salt, is a neuroactive steroid .
    17β-Estradiol sulfate-d4 sodium
  • HY-113441S
    3-Methoxy-4-Hydroxyphenylglycol sulfate-d3 potassium

    MHPG sulfate-d<sub>3sub> potassium

    		 Isotope-Labeled Compounds Others
    3-Methoxy-4-Hydroxyphenylglycol sulfate-d3 potassium is the deuterium labeled 3-Methoxy-4-Hydroxyphenylglycol sulfate potassium .
    3-Methoxy-4-Hydroxyphenylglycol sulfate-d3 potassium
  • HY-17459S
    Clopidogrel-d3 hydrogen sulfate

    (S)-(+)-Clopidogrel bisulfate-d<sub>3sub>; (S)-(+)-Clopidogrel-d<sub>3sub> hydrogen sulfate

    		 P2Y Receptor Cytochrome P450 Cardiovascular Disease
    Clopidogrel-d3 (hydrogen sulfate) is the deuterium labeled Clopidogrel hydrogen sulfate . Clopidogrel hydrogen sulfate is an antiplatelet agent to prevent blood clots. Clopidogrel hydrogen sulfate inhibits CYP2B6 and CYP2C19 with IC50s of 18.2 nM and 524 nM, respectively. Clopidogrel hydrogen sulfate is a potent antithrombotic agent that inhibits ADP-induced platelet aggregation．Clopidogrel hydrogen sulfate also is an orally active P2Y(12) inhibitor [6].
    Clopidogrel-d3 hydrogen sulfate
  • HY-W284558S
    Sodium hexadecyl sulfate-d33

    sodium hexadecyl sulphate-d<sub>33sub>

    		 Isotope-Labeled Compounds Others
    Sodium hexadecyl sulfate-d33 is the deuterium labeled Sodium hexadecyl sulfate .
    Sodium hexadecyl sulfate-d33
  • HY-129480
    Vertilmicin sulfate

    		Drug Intermediate Others
    Vertilmicin sulfate combines with FMOC-Cl to form the Vertilmicin-FMOC-Cl adduct, and can be used for the determination of glucosamine sulfate in plasma .
    Vertilmicin sulfate
  • HY-113238AS
    Lithocholic acid 3-sulfate-d4 disodium

    Sulfolithocholic acid-d<sub>4sub> disodium

    		 Isotope-Labeled Compounds Others
    Lithocholic acid 3-sulfate-d4 (disodium) is the deuterium labeled Lithocholic acid 3-sulfate disodium .
    Lithocholic acid 3-sulfate-d4 disodium
  • HY-14650
    DHEA
    30+ Cited Publications

    Prasterone; Dehydroisoandrosterone; Dehydroepiandrosterone

    		 Androgen Receptor Endogenous Metabolite Cardiovascular Disease Endocrinology Cancer
    DHEA (Prasterone) is one of the most abundant steroid hormones. DHEA (Prasterone) mediates its action via multiple signaling pathways involving specific membrane receptors and via transformation into androgen and estrogen derivatives (e.g., androgens, estrogens, 7α and 7β DHEA, and 7α and 7β epiandrosterone derivatives) acting through their specific receptors.
    DHEA
  • HY-126855S
    Cholic acid 7-sulfate-d4

    7-Sulfocholic acid-d<sub>4sub>

    		 Isotope-Labeled Compounds G protein-coupled Bile Acid Receptor 1 MHC Metabolic Disease
    Cholic acid 7-sulfate-d4 (7-Sulfocholic acid-d4) is the deuterium labeled Cholic acid 7-sulfate (HY-126855). Cholic acid 7-sulfate is a selective agonist targeting TGR5 (EC50=0.17 μM) and a ligand for MHC class I-related protein (MR1). As a gut-restricted TGR5 agonist, cholic acid 7-sulfate binds to TGR5 on enteroendocrine L cells, induces GLP-1 secretion, and improves glucose tolerance in a TGR5-dependent manner. Cholic acid 7-sulfate also acts as an endogenous ligand for MR1, promoting the survival of mucosal-associated invariant T cells MAIT and the expression of homeostatic gene signatures, affecting MAIT cell development and function. Cholic acid 7-sulfate is mainly used in the research of diabetes and MAIT cell-related immune regulation .
    Cholic acid 7-sulfate-d4
  • HY-W744217
    7-Hydroxy coumarin sulfate-d5 potassium

    7-HCS-d<sub>5sub>(potassium)

    		 Isotope-Labeled Compounds Endogenous Metabolite Metabolic Disease
    7-Hydroxy coumarin sulfate-d5 potassium (7-HCS-d5 potassium) is the deuterium labeled 7-Hydroxy coumarin sulfate potassium (HY-129977). 7-Hydroxy coumarin sulfate (7-HCS) potassium is a metabolite of 7-Ethoxycoumarin (HY-133091) .
    7-Hydroxy coumarin sulfate-d5 potassium
  • HY-10844S1
    Pretomanid-d5

    PA-824-d<sub>5sub>; (S)-PA 824-d<sub>5sub>

    		 Antibiotic Bacterial Isotope-Labeled Compounds Infection Cancer
    Pretomanid-d5 is deuterated labeled Pretomanid (HY-10844). Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 μg/mL.
    Pretomanid-d5
  • HY-148682S2
    18β-Glycyrrhetyl-3-O-sulfate-d3

    Glycyrrhetic acid 3-O-(hydrogen sulfate)-d<sub>3sub>

    		 Isotope-Labeled Compounds Others
    18β-Glycyrrhetyl-3-O-sulfate-d3 is the deuterium labeled 18β-Glycyrrhetyl-3-O-sulfate (HY-148682) .
    18β-Glycyrrhetyl-3-O-sulfate-d3
  • HY-148682S1
    18β-Glycyrrhetyl-3-O-sulfate-d2

    Glycyrrhetic acid 3-O-(hydrogen sulfate)-d<sub>2sub>

    		 Isotope-Labeled Compounds Others
    18β-Glycyrrhetyl-3-O-sulfate-d2 is the deuterium labeled 18β-Glycyrrhetyl-3-O-sulfate (HY-148682) .
    18β-Glycyrrhetyl-3-O-sulfate-d2
  • HY-P10215
    Ac-{Cpg}-Thr-Ala-{Ala(CO)}-Asp-{Cpg}-NH2

    		Parasite Infection
    Ac-{Cpg}-Thr-Ala-{Ala(CO)}-Asp-{Cpg}-NH2 (compound 40) is a potent Plasmodium subtilisin-like protease 1 (SUB1) inhibitor. SUB1-IN-1 shows IC50 values of 12 nM and 10 nM against P. vivax and P. falciparum SUB1 (Pv- and PfSUB1), respectively .
    Ac-{Cpg}-Thr-Ala-{Ala(CO)}-Asp-{Cpg}-NH2
  • HY-14650R
    DHEA (Standard)

    Prasterone (Standard); Dehydroisoandrosterone (Standard); Dehydroepiandrosterone (Standard)

    		 Androgen Receptor Endogenous Metabolite Metabolic Disease
    DHEA (Prasterone) (Standard) is the analytical standard of DHEA. This product is intended for research and analytical applications. DHEA is a steroid hormone .
    DHEA (Standard)
  • HY-W094477D
    Magnesium sulfate heptahydrate, for molecular biology

    Epsom salts, for molecular biology

    		 Biochemical Assay Reagents Others Cancer
    Magnesium sulfate heptahydrate, for molecular biology is a biochemical assay reagent and is suitable fo molecular biology.
    Magnesium sulfate heptahydrate, for molecular biology
  • HY-W094475C
    Magnesium sulfate heptahydrate, for cell culture

    Epsom salts, for cell culture

    		 Biochemical Assay Reagents Others Cancer
    Magnesium sulfate heptahydrate, for cell culture is a biochemical assay reagent and is suitable fo cell culture .
    Magnesium sulfate heptahydrate, for cell culture
  • HY-119695S
    Simvastatin acid-d6

    Tenivastatin-d<sub>6sub>

    		 Isotope-Labeled Compounds HMG-CoA Reductase (HMGCR) Reactive Oxygen Species (ROS) Cardiovascular Disease Cancer
    Simvastatin acid-d6 (Tenivastatin-d6) is deuterium labeled Simvastatin acid. Simvastatin acid (Tenivastatin), a hydrolysate of Simvastatin (HY-17502), is a HMG-CoA reductase (HMGCR) inhibitor. Simvastatin acid reduces Indoxyl sulfate-mediated reactive oxygen species (ROS) production in human cardiomyocytes. Simvastatin acid can also modulates OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with the OATP3A1 gene .
    Simvastatin acid-d6
  • HY-119695AS
    Simvastatin acid-d6 ammonium

    Tenivastatin-d<sub>6sub> ammonium

    		 Isotope-Labeled Compounds Endogenous Metabolite Cardiovascular Disease
    Simvastatin acid-d6 (ammonium)mis the deuterium labeled Simvastatin acid ammonium. Simvastatin ammonium is an active metabolite of simvastatin lactone mediated by CYP3A4/5 in the intestinal wall and liver (pKa=5.5). Simvastatin ammonium reduces indoxyl sulfate-mediated reactive oxygen species and modulates OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with the OATP3A1 gene .
    Simvastatin acid-d6 ammonium
  • HY-B0715S
    Pentoxifylline-d6

    BL-191-d<sub>6sub>; PTX-d<sub>6sub>; Oxpentifylline-d<sub>6sub>

    		 Phosphodiesterase (PDE) Autophagy HIV Cardiovascular Disease Cancer
    Pentoxifylline-d6 is the deuterium labeled Pentoxifylline. Pentoxifylline (BL-191), a haemorheological agent, is an orally active non-selective phosphodiesterase (PDE) inhibitor, with immune modulation, anti-inflammatory, hemorheological, anti-fibrinolytic and anti-proliferation effects. Pentoxifylline can be used for the research of peripheral vascular disease, cerebrovascular disease and a number of other conditions involving a defective regional microcirculation .
    Pentoxifylline-d6
  • HY-15494S1
    Picropodophyllin-d6

    AXL1717-d<sub>6sub>; Picropodophyllotoxin-d<sub>6sub>; PPP-d<sub>6sub>

    		 Isotope-Labeled Compounds IGF-1R Apoptosis Endocrinology Cancer
    Picropodophyllin-d6 (AXL1717-d6) is deuterium labeled Picropodophyllin. Picropodophyllin (AXL1717) is a selective insulin-like growth factor-1 receptor (IGF-1R) inhibitor with an IC50 of 1 nM.
    Picropodophyllin-d6
  • HY-B1873S
    Methoxychlor-d6

    DMDT-d<sub>6sub>; Methoxcide-d<sub>6sub>; Methoxy-DDT-d<sub>6sub>

    		 Isotope-Labeled Compounds Others
    Methoxychlor-d6 is the deuterium labeled Methoxychlor .
    Methoxychlor-d6
  • HY-E70171
    Heparan Sulfate 3-O-Sulfotransferase 1

    EC:2.8.2.23; HS3ST1

    		 Biochemical Assay Reagents Endocrinology
    Heparan Sulfate 3-O-Sulfotransferase 1 is a sulfotransferase. Heparan Sulfate 3-O-Sulfotransferase controls cellular production of the anticoagulant heparan sulfate related structure .
    Heparan Sulfate 3-O-Sulfotransferase 1
  • HY-B0236S
    6-Aminocaproic acid-d6

    EACA-d<sub>6sub>; Epsilon-Amino-n-caproic acid-d<sub>6sub>; 6-Aminohexanoic acid-d<sub>6sub>

    		 Isotope-Labeled Compounds Metabolic Disease
    6-Aminocaproic acid-d6 is deuterium labeled 6-Aminocaproic acid. 6-Aminocaproic acid (EACA), a monoamino carboxylic acid, is a potent and orally active inhibitor of plasmin and plasminogen. 6-Aminocaproic acid is a potent antifibrinolytic agent. 6-Aminocaproic acid prevents clot lysis through the competitive binding of lysine residues on plasminogen, inhibiting plasmin formation and reducing fibrinolysis. 6-Aminocaproic acid can be used for the research of bleeding disorders .
    6-Aminocaproic acid-d6
  • HY-B1850S
    Halosulfuron-methyl-d6

    Inpool-d<sub>6sub>; MON 12000-d<sub>6sub>; Manage-d<sub>6sub>

    		 Isotope-Labeled Compounds Herbicide Others
    Halosulfuron-methyl-d6 (Inpool-d6) is deuterium labeled Halosulfuron-methyl. Halosulfuron-methyl is a pyrazole sulfonylurea herbicide .
    Halosulfuron-methyl-d6
  • HY-N1214S
    Squalene-d6

    Super Squalene-d<sub>6sub>; trans-Squalene-d<sub>6sub>; AddaVax-d<sub>6sub>

    		 Isotope-Labeled Compounds Others
    Squalene-d6 is a deuterium labeled Squalene. Squalene (Super Squalene) is an intermediate product in the synthesis of cholesterol, and shows several pharmacological properties such as hypolipidemic, hepatoprotective, antiatherosclerotic, cardioprotective, antioxidant, and antitumour activity .
    Squalene-d6
  • HY-N0537S9
    Xylose-d6

    D-(+)-Xylose-d<sub>6sub>; (+)-Xylose-d<sub>6sub>; Wood sugar-d<sub>6sub>

    		 Isotope-Labeled Compounds Endogenous Metabolite Others
    Xylose-d6 is the deuterium labeled Xylose.
    Xylose-d6
  • HY-B0696S
    Tiagabine-d6

    NO050328-d<sub>6sub>; NO328-d<sub>6sub>; TGB-d<sub>6sub>

    		 Isotope-Labeled Compounds GABA Receptor Neurological Disease
    Tiagabine-d6 (NO050328-d6) is deuterium labeled Tiagabine. Tiagabine (NO050328) is a potent and selective GABA reuptake inhibitor, used as an anticonvulsant agent, with IC50s of 67, 446 and 182 nM for [ 3H]GABA uptake in Synaptosomes, Neurons and Glia, respectively .
    Tiagabine-d6
  • HY-B0457S1
    Clomipramine-d6 hydrochloride

    Chlorimipramine-d<sub>6sub> hydrochloride; G-34586-d<sub>6sub> hydrochloride; NSC-169865-d<sub>6sub> hydrochloride

    		 Isotope-Labeled Compounds Serotonin Transporter Neurological Disease
    Clomipramine-d6 (hydrochloride) is the deuterium labeled Clomipramine hydrochloride. Clomipramine (Chlorimipramine) hydrochloride is a potent 5-HT reuptake blocker with the IC50 value of 1.5 nM. Clomipramine hydrochloride is a tricyclic antidepressant that can be used for the research of depression and obsessive compulsive disorder (OCD) .
    Clomipramine-d6 hydrochloride

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