2. MAPK/ERK Pathway Apoptosis
  3. MEK Apoptosis
  4. Selumetinib sulfate (Standard)

Selumetinib sulfate (Standard) 

Cat. No.: HY-50706AR Purity: ≥98%
Handling Instructions Technical Support

Selumetinib (sulfate) (Standard) is the analytical standard of Selumetinib (sulfate). This product is intended for research and analytical applications. Selumetinib (AZD6244) is selective, non-ATP-competitive oral MEK1/2 inhibitor, with an IC50 of 14 nM for MEK1. Selumetinib (AZD6244) inhibits ERK1/2 phosphorylation.

For research use only. We do not sell to patients.

Selumetinib sulfate (Standard) Chemical Structure

Selumetinib sulfate (Standard) Chemical Structure

CAS No. : 943332-08-9

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Description

Selumetinib (sulfate) (Standard) is the analytical standard of Selumetinib (sulfate). This product is intended for research and analytical applications. Selumetinib (AZD6244) is selective, non-ATP-competitive oral MEK1/2 inhibitor, with an IC50 of 14 nM for MEK1. Selumetinib (AZD6244) inhibits ERK1/2 phosphorylation.

Molecular Weight

555.76

Formula

C17H17BrClFN4O7S
CAS No.
SMILES

OCCONC(C(C=C1C(N=CN1C)=C2F)=C2NC3=C(C=C(Br)C=C3)Cl)=O.O=S(O)(O)=O
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Selumetinib sulfate (Standard) Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Selumetinib sulfate (Standard)943332-08-9MEKApoptosisMitogen-activated protein kinase kinaseMAPKKMAP2KInhibitorinhibitorinhibit

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