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Analog

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Nucleoside Antimetabolite/Analog (1389) 5-HT Receptor (9) ADC Linker (2) ADC Payload (18) Adenosine Deaminase (5) Adenosine Receptor (8) Adenylate Cyclase (6) Adrenergic Receptor (7) Akt (10) Aldehyde Dehydrogenase (ALDH) (1) Amine N-methyltransferase (2) Amino Acid Derivatives (11) Aminopeptidase (2) AMPK (14) Amylin Receptor (5) Amyloid-β (6) Anaplastic lymphoma kinase (ALK) (3) Androgen Receptor (4) Angiotensin Receptor (9) Angiotensin-converting Enzyme (ACE) (2) Antibiotic (35) Antibody-Drug Conjugates (ADCs) (1) Antifolate (6) Apelin Receptor (APJ) (1) Apoptosis (128) Arrestin (3) ATF6 (2) Atg8/LC3 (2) ATGL (1) ATM/ATR (2) ATP Synthase (1) Autophagy (40) AUTOTACs (2) Bacterial (71) Bcl-2 Family (10) Bcr-Abl (3) BCRP (1) Beta-lactamase (1) Biochemical Assay Reagents (98) Bombesin Receptor (1) Bradykinin Receptor (1) Btk (5) c-Kit (1) c-Met/HGFR (4) c-Myc (1) Calcineurin (1) Calcium Channel (27) CaMK (6) Cannabinoid Receptor (23) Carbonic Anhydrase (1) Casein Kinase (1) 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PACAP Receptor (1) PAK (1) PANK (1) Parasite (33) PARP (1) PDGFR (1) PDHK (2) Peptide-Drug Conjugates (PDCs) (2) PERK (2) PGE synthase (1) Phosphatase (4) Phosphodiesterase (PDE) (16) Phospholipase (7) Phytohormone (2) PI3K (6) PINK1/Parkin (1) PKA (26) PKC (8) PKD (3) PKG (3) Platelet-activating Factor Receptor (PAFR) (3) Polo-like Kinase (PLK) (3) Poly(ADP-ribose) Glycohydrolase (PARG) (1) Potassium Channel (9) PPAR (7) Progesterone Receptor (7) Prostaglandin Receptor (97) PROTAC Linkers (6) PROTACs (4) Protease Activated Receptor (PAR) (2) Proteasome (2) Protein Arginine Deiminase (1) Proton Pump (1) PSMA (1) PTHR (2) Pyruvate Kinase (1) Radionuclide-Drug Conjugates (RDCs) (6) Raf (1) RAR/RXR (6) Ras (9) Reactive Oxygen Species (ROS) (21) Reference Standards (75) RET (3) Reverse Transcriptase (11) RIP kinase (4) ROCK (2) ROR (1) RSV (2) SARS-CoV (17) SGLT (1) Sialyltransferase (2) Sirtuin (5) Small Interfering RNA (siRNA) (1) SOD (3) Sodium Channel (6) Somatostatin Receptor (12) 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By Research Areas:	Cancer (1456) Cardiovascular Disease (120) Endocrinology (107) Infection (244) Inflammation/Immunology (186) Metabolic Disease (209) Neurological Disease (237)
Click Chemistry:	Labeling and Fluorescence Imaging (1) DBCO (4) PROTAC Synthesis (2) Azide (75) Alkynes (54)
Oligonucleotides:	Adenosine (257) Nucleoside Phosphoramidites (36) Inosine Nucleoside (1) Guanosine (129) Nucleotide Analogs (15) Thymine (3) Adenine (11) Thymidine (33) Phospholipids (2) Cap Analogs (17) Cytidine (146) Adenine Nucleotide (4) Guanine (4) Cholesterol (1) Cytidine Nucleotide (1) Guanine Nucleotide (2) Nucleoside Analogs (1200) Aptamers (2) Uridine (413) Inosine (41) Hypoxanthine (3) Cytosine (8) Uracil (7)

3049

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

179

Peptides

Inhibitory Antibodies

148

Natural
Products

Isotope-Labeled Compounds

134

Click Chemistry

1272

Oligonucleotides

Targets Recommended: Nucleoside Antimetabolite/Analog

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-10531

ARRY-380 analog	Caspase	Infection Cancer
ARRY-380 analog (Compound PCM-0095494) is an ARRY-380 (HY-16069) analog. ARRY-380 analog activates caspases 3 and caspases 8. ARRY-380 analog inhibits Salmonella replication in cells .

HY-136203

*Resveratrol analog* 1**	IKK Autophagy Mitophagy Sirtuin	Inflammation/Immunology Cancer
Resveratrol analog 1 is an analog of Resveratrol (HY-16561), compound 48. Resveratrol is a natural polyphenolic phytoalexin that possesses anti-oxidant, anti-inflammatory, cardioprotective, and anti-cancer properties.

HY-19346

*AR-13324 analog* mesylate**	ROCK	Others
AR-13324 analog mesylate is an analog of AR-13324. AR-13324 is an ROCK and norepinephrine transporter (NET) inhibitor .

HY-136204

*Resveratrol analog* 2**	IKK Autophagy Mitophagy Sirtuin	Inflammation/Immunology Cancer
Resveratrol analog 2 is an *analog* of Resveratrol (HY-16561). Resveratrol is a natural polyphenolic phytoalexin that possesses anti-oxidant, anti-inflammatory, cardioprotective, and anti-cancer properties .

HY-124417

SBI-477 analog	GLUT	Metabolic Disease
SBI-477 (compound 41) analog inhibits intracellular lipid accumulation, increase celluar glucose uptake .

HY-29090

ML228 analog	HIF/HIF Prolyl-Hydroxylase	Cancer
ML228 analog is an analog of ML228 (HY-12754). ML228 is a potent activator of HIF .

HY-127178

*ML120 analog* 1**	Phosphatase	Cancer
ML120 analog 1 (compound 1) is a competitive inhibitor with a K_i of 0.69 μM for Hematopoietic protein tyrosine phosphatase (HePTP) .

HY-W814315

Alectinib analog CH5424802 Analog; RO5424802 Analog; RG7853 Analog	Anaplastic lymphoma kinase (ALK)	Cancer
Alectinib analog (CH5424802 analog) is a selective ALK inhibitor with activity in blocking resistance gating mutations. The synthetic optimization of alectinib analog allows it to be combined with specific peptides to improve the ability to target cancer cells. Alectinib analog exhibits low micromolar IC50 values in antiproliferation and shows good cytotoxic effects. The inhibitory activity of alectinib analog is closely related to its stability and release of active ingredients. Alectinib analog demonstrated the ability to inhibit vascular septal length or width in an in vivo zebrafish model .

HY-169158

*Bortezomib analog* 1**	Ligands for Target Protein for PROTAC	Cancer
Bortezomib analog 1 is an analog of Bortezomib (HY-10227). Bortezomib analog 1 and can be used to synthesize PROTAC 20S proteasome subunit β5 degrader 1 (HY-169134) .

HY-107502

*Cryptophycin analog* 1**	Antibody-Drug Conjugates (ADCs)	Cancer
Cryptophycin analog 1 is an ADC payload. Cryptophycin analog 1 shows anticancer activity. Cryptophycin analog 1 displays cell activity an order of magnitude more potent than approved ADC payloads MMAE and DM1 .

HY-163836

*HMBPP analog* 1**	Drug Derivative	Others
HMBPP analog 1 (6e), a Trifluoromethyl analog, is the weakest agonist but the strongest inhibitor HMBPP ELISA response .

HY-N10492

*Spongionellol A analog* 1**	P-glycoprotein	Cancer
Spongionellol A analog 1, an analog of Spongionellol A (HY-10491), is a MDR1 (p-glycoprotein) inhibitor. Spongionellol A analog 1 has high cytotoxic activity and selectivity in prostate cancer cells by inducing caspase?dependent apoptosis. Spongionellol A analog 1 can be used in the research of cancers, such as prostate cancer .

HY-128979

*Deruxtecan analog* 2**	Drug-Linker Conjugates for ADC	Cancer
Deruxtecan analog 2 (example 9 P3) is a Deruxtecan (HY-13631E) analog. Deruxtecan analog 2 is a agent-linker conjugate composed of Camptothecin (HY-16560) and a linker. Camptothecin (CPT) is a Topo I inhibitor with antineoplastic activity against colorectal, breast, lung and ovarian cancers. Deruxtecan analog 2 can be used for the preparation anti-FGFR2 ADC .

HY-148091

*Duocarmycin analog-2*	DNA Alkylator/Crosslinker	Cancer
Duocarmycin analog-2 is a potent DNA alkylating agent. Duocarmycin analog-2 can be used of synthetic immunoconjugate. Duocarmycin analog-2 has antitumor activity .

HY-115666

*COH34 analog* 1**	Poly(ADP-ribose) Glycohydrolase (PARG)	Cancer
COH34 analog 1, a metabolite, is an oxidized analog of COH34. COH34 is a potent poly(ADP-ribose) glycohydrolase (PARG) inhibitor .

HY-153511

*Rapamycin analog-2*	Others	Cancer
Rapamycin analog-2 (compound A) is a Rapamycin analog .

HY-171164

*Nirmatrelvir analog-1*	Drug Intermediate	Infection
Nirmatrelvir analog-1 (Compound 234) is an analog of Nirmatrelvir (HY-138687). Nirmatrelvir analog-1 can be used as drug intermediate for synthesis of cysteine protease .

HY-156670

*Camptothecin analog-1*	Topoisomerase	Others
Camptothecin analog-1 (Comp 166) is a camptothecin analog .

HY-129355

Duocarmycin Analog	ADC Payload DNA Alkylator/Crosslinker	Cancer
Duocarmycin Analog is an analog of Duocarmycin, and used as an DNA alkylator and ADC cytotoxin .

HY-18298

*PD 173955 analog* 1**	EGFR	Cancer
PD 173955 analog 1 (Compound 26) is an analog of PD 173955 (HY-10395). PD 173955 analog 1 is an inhibitor for EGFR kinase, which exhibits antitumor and toxicological properties. PD 173955 analog 1 exhibits an in silico IC₅₀ of 0.19 μM .

HY-149441

*Indisulam analog-1*	Molecular Glues	Cancer
Indisulam analog-1 (Compound 4) is an analog of Indisulam (HY-13650). Indisulam analog-1 recruits DCAF15-DDB1-DDA1-RBM39 with an EC₅₀ of 1.21 µM. Indisulam analog-1 can be used in the research of colon cancer .

HY-48878

*Exatecan analog* 36**	ADC Payload Topoisomerase	Cancer
Exatecan analog 36 is a analog of Exatecan (HY-13631). Exatecan (DX-8951) is a common toxin component in ADC preparation (ADC Cytotoxin) and an inhibitor of DNA topoisomerase I (IC50=2.2 μM) .

HY-164861

*Camptothecin analog-2*	Drug Derivative	Cancer
Camptothecin analog-2 (Compound 7b-2) is a camptothecin derivative. Camptothecin analog-2 can be used in the study of cancer .

HY-128004

*ML171 analog* 1**	NADPH Oxidase	Cancer
ML171 analog 1 (Crop ID: SR-03000000698-1 SID: 57287906) is a NOX1 inhibitor. ML171 analog 1 can be used in cancer research .

HY-128606

*Thiamine diphosphate analog* 1**	Drug Derivative	Metabolic Disease
Thiamine diphosphate analog 1 is an analog of Thiamine diphosphate . Thiamine diphosphate is the active form of vitamin B₁. Thiamine diphosphate a universal cofactor involved in pivotal cellular pathways .

HY-172027

Remdesivir methylpropyl ester analog GS-5734 methylpropyl ester Analog	SARS-CoV	Infection
Remdesivir methylpropyl ester analog (GS-5734 methylpropyl ester analog) is a derivative of Remdesivir (HY-104077). Remdesivir is a nucleoside analogue with effective antiviral activity.

HY-156883

*Dasatinib analog-1*	Cytochrome P450	Others
Dasatinib analog-1 (compound 5826) inhibits CYP3A4 viability with a K_i value of 5.4 μM. Dasatinib analog-1 blocks the formation of glutathione adducts .

HY-P1577

Dermorphin Analog	Opioid Receptor	Inflammation/Immunology
Dermorphin Analog is an analog of Dermorphin. Dermorphin is a natural heptapeptide μ-opioid receptor agonist found in amphibian skin.

HY-135593

*LY88074 analog* 1**	Others	Endocrinology
LY88074 analog 1 is a benzothiophene compound with nitrogen-containing non-basic side chains, Compound 26, extracted from patent EP0747380A1. LY88074 analog 1 is an agent for alleviating the symptoms of post-menopausal symptoms, such as osteoporosis, cardiovascular related pathological conditions, and estrogen-dependent cancer. LY88074 analog 1 can be used alone or in combination with estrogen or progestin .

HY-135237

*DB04760 analog* 1**	Drug Derivative	Neurological Disease Cancer
DB04760 analog 1 is an analogue of DB04760.

HY-19430

Pimelic Diphenylamide 106 analog 2 Publications Verification RGFA-8 Analog; TC-H 106 Analog	HDAC	Cancer
Pimelic Diphenylamide 106 analog is the analog of Pimelic Diphenylamide 106, with unknown activity.

HY-15966A

*GSK2110183 analog* 1 hydrochloride**	Akt	Cancer
GSK2110183 analog 1 hydrochloride is the structural analogue of GSK2110183.

HY-15966

*GSK2110183 analog* 1**	Akt	Cancer
GSK2110183 analog 1 is the structural analogue of GSK2110183.

HY-159902

*KRN7000 analog* 3**	Interleukin Related	Inflammation/Immunology Cancer
KRN7000 analog 3 (Compound 14),α-GalCer (HY-102022) analogue, is a iNKT agonist. KRN7000 analog 3 induces higher levels of IL-2 cytokine secretion (49.2-62.6 ng/mL) than a-GalCer (44.1 ng/mL) in mNK1.2 cells. KRN7000 analog 3 is promising for research of antitumor agents and vaccine adjuvants .

HY-W098008

*Fenbendazole analog-1*	Parasite Microtubule/Tubulin	Infection
Fenbendazole analog-1 (compound 9) is a 2-methoxycarbonylamino-derived antiparasitic compound and inhibits rat brain tubulin polymerization. Fenbendazole analog-1 inhibits the growth of the protozoa Giardia lamblia, Entamoeba histolytica, and the worm Trichinella spiralis .

HY-172089

*TG101209 analog* 1**	Apoptosis	Cancer
TG101209 analog 1 (Compound 8h) is an inhibitor for BUB1B with an IC₅₀ of 10.36 μM. TG101209 analog 1 exhibits cytotoxicity (IC₅₀ for Caki-1 is 1.347 μM), induce necrosis and apoptosis .

HY-169144

Bortezomib analog	Proteasome	Cancer
Bortezomib analog (Compound 13), an analog of Bortezomib (HY-10227), is an active control of 20S proteasome subunit β5 ligand.

HY-10976

Luminespib analog	Drug Derivative	Others
Luminespib analog is an active compound.

HY-163704

*KRN7000 analog* 1**	IFNAR Interleukin Related	Inflammation/Immunology Cancer
KRN7000 analog 1 exhibits good Th1-biased immune response through induction of interferon-γ (IFN-γ) and reduction of interleukin-4 (IL-4). KRN7000 analog 1 is potential as an antitumor agent and vaccine adjuvant .

HY-163772

*Fraxinellone analog* 1**	Keap1-Nrf2	Neurological Disease
Fraxinellone analog 1 (compound 2) is a potent and rapid activator of the Nrf2 mediated antioxidant defense system, which protects against glutamate-mediated excitotoxicity and induces the expression of antioxidant genes Gpx4, Sod1, and Nqo1. Fraxinellone analog 1 has neuroprotective effects and regulatory effects against oxidative stress and inflammation, and can be used in the study of neurodegenerative diseases .

HY-159874

*KRN7000 analog* 2**	Interleukin Related	Cancer
KRN7000 analog 2 is a iNKT agonist, which is promising for research of antitumor agents and vaccine adjuvants.

HY-146146

Kolavenic acid analog KAA	Kinesin	Cancer
Kolavenic acid analog (KAA) is an anticancer agent. Kolavenic acid analog shows strong activity against HSET-overproducing yeast cells. Kolavenic acid analog inhibits centrosome clustering in human cancer cells containing high HSET levels and supernumerary centrosomes .

HY-P2178

*Dihydrochlamydocin analog-1*	HDAC	Cancer
Dihydrochlamydocin analog-1 (compound 2) is a Chlamydocin (HY-115761) analogue that inhibits histone H4 peptide deacetylation with IC₅₀ of 30 nM .

HY-121701

SR33805 analog	Calcium Channel	Cardiovascular Disease
SR 33805 (analog) is an orally active Ca ²⁺ channel blocker that selectively inhibits the proliferation of smooth muscle cells. SR 33805 (analog) reduces calcium uptake by blocking calcium channels, thereby inhibiting smooth muscle cell proliferation induced by serum, platelet-derived growth factor, and basic fibroblast growth factor. SR 33805 (analog) significantly reduces intimal thickening following endothelial injury in rabbits. SR 33805 (analog) shows promise for cardiovascular disease research, such as in early atherosclerosis .

HY-10467

HCV-796 analog	Virus Protease	Infection
HCV-796 analog is a potent NS5B inhibitor that binds to the palm II site. HCV-796 analog is promising for research of hepatitis C (HCV) infections .

HY-133875

*CE3F4 analog* 1** 1 Publications Verification	Ras	Metabolic Disease
CE3F4 analog 1 is an analogue of CE3F4 .

HY-114184

MK-8245 analog	Stearoyl-CoA Desaturase (SCD)	Metabolic Disease
MK-8245 analog (compound 6) is a potent stearoyl-CoA desaturase (SCD) inhibitor with an IC₅₀ of 7 nM for rat SCD. MK-8245 analog has antidiabetic and antidyslipidemic effects .

HY-128979B

*Deruxtecan analog* 2 monoTFA**	Drug-Linker Conjugates for ADC	Cancer
Deruxtecan analog 2 (monoTFA) is a homolog of Deruxtecan (HY-13631E), a conjugate of the ADC toxin DX-8951 derivative (Dxd) with an ADC Linker .

HY-P10219

*Brevicidine analog* 22**	Bacterial	Infection Inflammation/Immunology
Brevicidine analog 22 (22) exerts broad spectrum antimicrobial activity and excellent stability (t_1/2 = 40.98 h), with MICs of 2-16 μM for gram-negative and gram-positive bacteria .

HY-17658

*Apiol analog-1*	Apoptosis	Cancer
Apiol analog-1 (Compound 2b) is an analog of Apiol (HY-135217). Apiole is an anti-tumor agent that induces apoptosis and inhibits human colon cancer cells by inducing G0/G1 cell cycle arrest. Apiole also significantly inhibited colon tumor development in an in vivo mouse xenograft model .

Cat. No.	Product Name

HY-L0116V

Asinex Macrocycles for RNA Library

1,065 compounds

Macrocycles are promising scaffolds for the design of novel RNA targeting molecules. This collection of macrocycles for RNA consists of very diverse, drug-like molecules which incorporate certain known RNA-recognition elements (e.g. nucleobase ring systems and analogs) distributed within macrocyclic rings or peripheral fragments. As macrocyclic molecules tend to be larger than traditional screening molecules, it is vital to carefully assess and control their physicochemical properties. All macrocycles have been tested for aqueous and DMSO solubility with cutoffs applied at 10 mM in DMSO and 50 µM in PBS (pH 7.4); PAMPA permeability has also been tested for representative set of macrocycles.

HY-L027

Antiviral Compound Library

1,462 compounds

Viruses are much simpler organisms than bacteria, and they are made from protein substances and nucleic acid. Despite the fact that the exact mechanism of infection is extremely specific to each type of virus, the general scheme of infection can be represented in the following manner: A virus is absorbed at the surface of a host cell and then permeates through the membrane, where it releases nucleic acid from its protein protection. Then the viral nucleic acid begins to replicate, and transcription of the viral genome takes place either in the cytoplasm, or in the nucleus of the host cell. As a result of these events, a large amount of viral nucleic acid and protein are made to make new generations of virions. Therefore, one mechanism of action of antiviral drugs is to interfere with the ability of a virus to get into a target cell. A second mechanism of action is to target the processes that synthesize virus components after a virus invades a cell, such as nucleotide or nucleoside analogs.

MCE designs a unique collection of 1,462 anti-virus compounds that target several viruses, including SARS-CoV, HBV, HCV, HIV, HSV and Influenza Virus. It’s an effective tool for anti-virus drug discovery.

HY-L220

Biotoxin Library

84 compounds

Biotoxins, also referred to as natural toxins, are chemical substances produced by plants, animals, or microorganisms that exert toxic effects on other living organisms. Due to unique biological activities, biotoxins have been widely applied in molecular biology, physiology, pharmacology, and the clinical diagnosis and treatment of various human diseases, becoming an important source of natural drug development. Biotoxins can specifically bind to and interfere with intracellular signaling molecules or receptors, thereby altering cellular signaling processes. Leveraging this characteristic, biotoxins can be used to study the regulatory mechanisms of cellular signaling pathways. For example, neurotoxins such as snake venom peptides can be used to investigate the functional regulation of neurotransmitter receptors and ion channels. Additionally, biotoxins have demonstrated significant potential in drug development across various fields, including neurological diseases, cardiovascular diseases, anticoagulation, and anti-cancer therapies. With advancements in high throughput screening, structural optimization, and antibody-toxin conjugation technologies, numerous biotoxins or their structural analogs have been successfully brought to market, such as Ziconotide, Captopril, Bivalirudin, and Eptifibatide.

MCE offers 84 types of biotoxins, including neurotoxins, cardiotoxins, mycotoxins, and more.

HY-L918

Molecular Glue-like Compound Library

318 compounds

Targeted Protein Degradation (TPD) is a novel and promising approach to drug development. It shows great potential for targeting proteins traditionally considered "undruggable" due to the lack of enzymatic function and absence of binding sites by tagging them for degradation or recruiting natural degradation mechanisms.

Molecular glues are a type of small-molecule degraders that primarily induce novel interactions between E3 ubiquitin ligases and target proteins, forming ternary complexes that lead to protein ubiquitination and subsequent proteasomal degradation. Compared with PROTACs, molecular glues generally have lower molecular weights, higher cell permeability, and better drug-like properties. Additionally, the design of molecular glues is relatively simple, without the requirements for complex linkers and ligand optimization. As a result, molecular glues have gradually emerged as a promising therapeutic approach for various diseases.

Multiple types of molecular glues have been reported previously. Analysis of co-crystal complex structures reveals that CRBN-related molecular glues are more versatile. Therefore, MCE researchers select active molecules related to these targets as probes for artificial intelligence (AI) screening.Subsequently, molecular docking technology was used to verify whether the screened molecules retained the key pharmacophore features. Ultimately, we obtained 320 molecular glue analogs, and these compounds serve as powerful tools for the research of molecular glues.

Cat. No.	Product Name	Type

HY-15625

Hoechst 33258 analog 3

DNA Stain

Hoechst 33258 analog 3 is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution .

HY-15630A

Hoechst 33342 analog 2 trihydrochloride

DNA Stain

Hoechst 33342 analog 2 trihydrochloride is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution .

HY-15628

Hoechst 33258 analog 5

DNA Stain

Hoechst 33258 analog 5 is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution .

HY-15624

Hoechst 33258 analog 2

DNA Stain

Hoechst 33258 analog 2 is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution .

HY-15631

Hoechst 33258 analog 6

5+ Cited Publications

DNA Stain

Hoechst 33258 analog 6 is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution (Ex/Em = 356/451 nm) .

HY-15627

Hoechst 33342 analog

3 Publications Verification

DNA Stain

Hoechst 33342 analog is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution .

HY-15623

Hoechst 33258 analog

1 Publications Verification

DNA Stain

Hoechst 33258 analog is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution .

HY-107502

*Cryptophycin analog* 1**	Chromogenic Assays
Cryptophycin analog 1 is an ADC payload. Cryptophycin analog 1 shows anticancer activity. Cryptophycin analog 1 displays cell activity an order of magnitude more potent than approved ADC payloads MMAE and DM1 .

HY-15630

Hoechst 33342 analog 2

DNA Stain

Hoechst 33342 analog 2 is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution .

HY-115749A

(Rac)-Luciferin 6′-methyl ether sodium (Rac)-6′-Methoxyluciferin sodium	Fluorescent Dyes/Probes
D-Luciferin 6′-methyl ether (6′-Methoxyluciferin; compound 19a) sodium is a potent luciferase from the North American firefly Photinus pyralis (PpyLuc) inhibitor with an IC₅₀ of 0.1 μM. D-Luciferin 6′-methyl ether, a D-luciferin analog, shows non-specific interactions at ATP- and luciferin-binding sites of the PpyLuc active site .

HY-W012642A

2-Aminopurine dihydrochloride	Fluorescent Dyes/Probes
2-Aminopurine dihydrochloride is a fluorescent analog of guanosine. 2-Aminopurine dihydrochloride can be used as a fluorescence probe for nucleic acid structure and dynamics. Incorporating 2-Aminopurine dihydrochloride into DNA quenches its fluorescence .

HY-D1578

C12FDGlcU	Fluorescent Dyes/Probes
C12FDGlcU is a lipophilic analog of fluorescein di-β-D-glucuronic acid. C12FDGlcU can be useful for the detection of β-glucuronidase (GUS) gene expression. C12FDGlcU can enter the cells and then be cleaved by β-glucuronidase, generating the yellow-colored, green-fluorescent fluorescein (Abs/Em of the reaction product: 495/518 nm) .

HY-D1603

BODIPY FL-EDA

Fluorescent Dyes/Probes

BODIPY FL-EDA is a widely used fluorescent dye for quantitative analysis of nucleotides. BODIPY FL-EDA is an aliphatic amine analog that can react with aldehydes and ketones. BODIPY FL-EDA can be used to detect both modified and unmodified deoxynucleotides and to determine DNA damage and genomic DNA methylation through capillary electrophoresis with laser-induced fluorescence (CE-LIF). Additionally, it can be used for quantifying intracellular ATP levels. The excitation wavelength is 500 nm, and the emission wavelength is 510 nm .

HY-120993

1,N6-Ethenoadenosine 5'-monophosphate sodium

1,N6-Etheno-AMP sodium; 1,N6-ε-AMP sodium

Fluorescent Dyes/Probes

1,N6-Ethenoadenosine 5'-monophosphate (1,N6-Etheno-AMP) sodium is a highly fluorescent analog of adenosine 5'-monophosphate (AMP). 1,N6-Ethenoadenosine 5'-monophosphate sodium is a powerful probe for systems involving adenosine 5'-monophosphate and can be detected at low concentration. 1,N6-Ethenoadenosine 5'-monophosphate sodium has long wavelength of excitation (250-300 nm), and emission at 415 nm .

HY-D1028Y

DiD perchlorate (solution)	Fluorescent Dyes/Probes
DiD perchlorate (solution) is a long-chain carbocyanine dye. Carbocyanine dyes are widely used as Di to label cells, organelles, liposomes, viruses and lipoproteins .

HY-D1028

DiD perchlorate 20+ Cited Publications	Fluorescent Dyes/Probes
DiD is a long-chain carbocyanine dye. Carbocyanine dyes are widely used as Di to label cells, organelles, liposomes, viruses and lipoproteins .

HY-101937A

(±)-ANAP	Fluorescent Dyes/Probes
(±)-ANAP is the unnatural amino acid analog of prodan, acts as a fluorescent probes, and enhances environmental sensitivity.

HY-101937C

(±)-ANAP hydrochloride 1 Publications Verification	Fluorescent Dyes/Probes
(±)-ANAP hydrochloride is the unnatural amino acid analog of prodan, acts as a fluorescent probes, and enhances environmental sensitivity.

HY-110393

CLR1501	Fluorescent Dyes/Probes
CLR1501, a fluorescently labeled CLR1404 analog, is a cancer cell-selective fluorescence compound .

HY-129096

IDT307	Chromogenic Substrates
IDT307, an analog of the organic cation MPP+, is a specific fluorescent substrate for DAT (fluorescent substrate APP+) .

HY-141576

C6-NBD Sphinganine dhCerC6NBD	Fluorescent Dyes/Probes
C6-NBD Sphinganine is a sphinganine analog and can be used as fluorescent dye for labeling fatty acid .

HY-D1573

C6 NBD Phytoceramide	Fluorescent Dyes/Probes
C6 NBD Phytoceramide is a fluorescently labeled short-chain ceramide analog that can be recognized by mammalian GlcCer synthase (GCS) .

HY-138111

4-Nitrophenyl β-D-cellotetraoside

p-Nitopheyl β-D-cellotetaoside

Fluorescent Dyes/Probes

4-Nitrophenyl β-D-cellotetraoside (p-Nitopheyl β-D-cellotetaoside) is a small molecule cellulose mimetic consisting of a tetramer of D-glucose units linked by β-1-4 glycosidic bonds. The fragmentation pattern of 4-Nitrophenyl β-D-cellotetraoside after enzymatic hydrolysis can be analyzed by TLC or by the release of 4-nitrophenol, which has a strong absorbance at 395 nm in alkaline solutions. 4-Nitrophenyl β-D-cellotetraoside can be used in cellulose degradation studies to determine the specificity of cellulases .

HY-D1617

BODIPY 500/510 C1, C12

1 Publications Verification

Fluorescent Dyes/Probes

BODIPY 500/510 C1, C12 is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells . Maximum excitation/emission wavelength: 500/510 nm . Protect from light, stored at -20℃.

HY-133885

S-(-)-7-Desmethyl-8-nitro blebbistatin	Dyes
S-(-)-7-Desmethyl-8-nitro blebbistatin (compound 12) is an analog of (-)-Blebbistatin (HY-13441). (-)-Blebbistatin is a selective non-muscle myosin II inhibitor .

HY-120649

SKM 4-45-1	Fluorescent Dyes/Probes
SKM 4-45-1 is an analog of Anandamide (AEA)(HY-10863). SKM 4-45-1 is a fluorescent substrate, that can be used to study the transmembrane carrier-mediated transport of AEA across cell membranes .

HY-125746

BODIPY-Cholesterol 10+ Cited Publications	Fluorescent Dyes/Probes
BODIPY-cholesterol is an intrinsically lipophilic, and cell-permeable analog of cholesterol with a fluorescent BODIPY group. BODIPY-cholesterol can be used to monitor sterol uptake and inter-organelle sterol flux in cells. (Excitation/Emission: 505/515 nm) .

HY-135367

pyCTZ Pyridyl CTZ	Fluorescent Dyes/Probes
pyCTZ (Pyridyl CTZ), a pyridyl Coelenterazine (CTZ) analog, and is an ATP-independent pyridyl substrate of LumiLuc luciferase. pyCTZ generates strong blue bioluminescence in the presence of luciferases. pyCTZ can be used for aequorin-based calcium sensing .

HY-108537

L 012 sodium salt 1 Publications Verification	Dyes
L 012 sodium salt is a luminal-based chemiluminescent probe. L 012 sodium salt can detect NADPH oxidase (Nox)-derived superoxide and nitrogen species (reactive oxygen species (ROS) and reactive nitrogen species (RNS)) .

HY-D1768

Fluo-4FF AM	Fluorescent Dyes/Probes
Fluo-4FF AM is a cell-permeant fluorescent calcium indicator. Fluo-4FF is an analog of Fluo-4 with a lower affinity for calcium, which is suitable for investigation of relatively high level of intracellular calcium.

HY-D1119

AF647-NHS ester	Fluorescent Dyes/Probes
AF647-NHS ester is an analog of Alexa Fluor 647 (AF647). AF647 is a far-red fluorescent dye with an excitation wavelength (λ_ex) of 635 nm (conventional fluorescence detection)/620 nm (instantaneous detection). Storage: Protect from light .

HY-121608

Lumiflavin Lumiflavine	Fluorescent Dyes/Probes
Lumiflavin (Lumiflavine), a riboflavine analog, causes significant inhibition of riboflavine uptake. Lumiflavin can effectively reduce the riboflavin enrichment in cancer stem-like cells (CSCs) and sensitize the effect of cisplatin Diamminedichloroplatinum (DDP) on CSCs. Lumiflavin is promising for research of ovarian cancer .

HY-D1749

C6 NBD L-threo-ceramide	Fluorescent Dyes/Probes
C6 NBD L-threo-ceramide is a cell-permeable analog of ceramides that is tagged with a fluorescent group C6 nitrobenzoxadiazole (C6 NBD). It is rapidly transferred between liposomes, labels the Golgi apparatus, and is metabolized to C6 NBD sphingomyelin in BHK cells and V79 fibroblasts.

HY-D1372

Cyanine3 amine hydrochloride	Fluorescent Dyes/Probes
Cyanine3 amine hydrochloride, an analog of Cyanine3 amine, is a potent green fluorescent dye. Cyanine3 amine hydrochloride has the primary amine group and is covalently coupled with reactive groups such as NHS esters, carboxy groups (after carbodiimide activation), and epoxides. (λ_ex=555 nm, λ_em=570 nm) .

HY-D1324

Cyanine5.5 hydrazide dichloride	Fluorescent Dyes/Probes
Cyanine5.5 hydrazide, an analog of Cyanine5.5 fluorophore, is a near-infrared (NIR) fluorescent dye. Cyanine5.5 hydrazide is used for labeling of biomolecules through the condensation between the hydrazide groups and the carbonyl groups. (λ_ex=684 nm, λ_em=710 nm) .

HY-D1596

Cyanine 3.5 chloride Cy3.5 NHS ester chloride; Cy 3.5 chloride	Fluorescent Dyes/Probes
Cyanine 3.5 (Cy3.5 NHS ester) chloride is an analog of Cy3.5 fluorophore. Cyanine 3.5 chloride is a reactive, red fluorescent dye. Cyanine 3.5 chloride is used for labeling of amino-groups in peptides, proteins, and oligonucleotides. (λ_ex=591 nm, λ_em=604 nm) .

HY-D1372A

Cyanine3 amine TFA	Fluorescent Dyes/Probes
Cyanine3 amine (TFA), an analog of Cyanine3 amine, is a potent green fluorescent dye. Cyanine3 amine (TFA) has the primary amine group and is covalently coupled with reactive groups such as NHS esters, carboxy groups (after carbodiimide activation), and epoxides. (λ_ex=555 nm, λ_em=570 nm) .

HY-W012642

2-Aminopurine	Fluorescent Dyes/Probes
2-Aminopurine, a fluorescent analog of guanosine and adenosine, is a widely used fluorescence-decay-based probe of DNA structure. When 2-Aminopurine is inserted in anoligonucleotide, its fluorescence is highly quenched by stacking with the natural bases. 2-Aminopurine has been used to probe nucleic acid structure and dynamics .

HY-D2757

5(6)-Carboxyrhodamine 110 NHS ester	Fluorescent Dyes/Probes
5(6)-Carboxyrhodamine 110 NHS Ester is the nonsulfonated analog of the BP Fluor 488 dye. The amine-reactive 5(6)-Carboxyrhodamine 110 NHS ester can be used to create bright and photostable green-fluorescent bioconjugates with excitation/emission maxima ~502/527 nm. The conjugates of this dye often used for Fluorescence Correlation Spectroscopy (FCS).

HY-D0967

Cy5-bifunctional dye	Dyes
Cy5-bifunctional dye is a Cy5 (HY-D0821) analog with two NHS esters. Cy5-bifunctional dye can be used to label the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules .

HY-D1596A

Cyanine 3.5 bromide Cy3.5 NHS ester bromide; Cy 3.5 bromide	Fluorescent Dyes/Probes
Cyanine 3.5 bromide (Cy3.5 NHS ester bromide) is an analog of the Cy3.5 fluorophore. Cyanine 3.5 bromide is a red reactive fluorescent dye. Cyanine 3.5 bromide is used to label amino groups in peptides, proteins, and oligonucleotides. (λ_ex=591 nm, λ_em=604 nm) .

HY-172721

Cy3B maleimide

Fluorescent Dyes/Probes

Cy3B maleimide is a mono-reactive dye containing maleimide group, which can selectively and efficiently attach Cyanine3 fluorophore (an analog of Cy3) to proteins and peptides containing cysteine residues, as well as to other thiolated molecules (such as thiol-containing oligonucleotides). Cy3B is an improved version of Cy3 dyes with significantly increased fluorescence quantum yield and photostability.

HY-D2869

Ac-H-FluNox	Fluorescent Dyes/Probes
Ac-H-FluNox LH is a cell-compatible H-FluNox (Labile heme-selective fluorescent probe) analog. Ac-H-FluNox LH removes the acetyl group through intracellular esterase hydrolysis to generate H-FluNox, which triggers fluorescence under the action of Labile heme by biomimetic N-oxide deoxygenation reaction, thereby achieving the detection of Labile heme .

HY-120317

CPTH2-Alkyne	Fluorescent Dyes/Probes
CPTH2-Alkyne is a cell active analog of CPTH2 (HY-W013274). CPTH2-Alkyne specifically accumulates in nucleoli and locates in nuclear periphery and in cytoplasma. CPTH2-Alkyne inhibits N-acetyltransferase 10 (NAT10). CPTH2-Alkyne is used in study of nuclear architecture and application in laminopathy .

HY-116215

2-NBDG

Maximum Cited Publications

61 Publications Verification

Fluorescent Dyes/Probes

2-NBDG is a fluorescently-labeled deoxyglucose analog that is used primarily to directly monitor glucose uptake by living cells and tissues. It is also used as a topical contrast reagent for the detection of neoplasia. 2-NBDG can be used in real-time confocal, high-resolution, or wide-field fluorescence microscopy as well as in flow cytometry. The probe can be excited by the Argon laser at 488 nm to give the environment-sensitive fluorescence. It has lower photostability than the rhodamine-based fluorescent probes.

HY-D1755

Fluo-3FF AM	Fluorescent Dyes/Probes
Fluo-3FF AM is a low affinity (Kd = 42 μM) fluorescent Ca ²⁺ sensitive indicator (Abs/Em = 462 nm/526 nm). Fluo-3FF AM is Mg ²⁺ insensitive and relatively photostable. Fluo-3FF AM is an analog of Fluo-3FF AM. Fluo-3FF AM is essentially non-fluorescent, but exhibits a strong fluorescence enhancement upon entry into cells and binding to calcium.

HY-D1447

Fluo-3FF pentapotassium

Fluorescent Dyes/Probes

Fluo-3FF pentapotassium is a cell-permeable acetoxy-methyl ester of Fluo-3FF, a fluorescent calcium indicator. Fluo-3FF is a di-fluorinated analog of Fluo-3 with a 100-fold lower affinity than Fluo-3 for calcium (Kds=42 and 0.4 μM, respectively). For its low affinity, Fluo-3FF is used for studying compartments with high concentrations of calcium, such as endoplasmic reticulum, where high affinity dyes will be insensitive to luminal fluctuations.

HY-107202GL

Polyinosinic-polycytidylic acid (GMP Like)

Poly(I:C) (GMP Like)

Fluorescent Dye

Polyinosinic-polycytidylic acid (Poly(I:C)) (GMP Like) is the GMP Like class Polyinosinic-polycytidylic acid (HY-107202), and can be used as pharmaceutical excipients. Polyinosinic-polycytidylic acid (Poly(I:C)) is a synthetic analog of double-stranded RNA and an agonist of toll-like receptor 3 (TLR3) and retinoic acid inducible gene I (RIG-I)-like receptors (RIG-I and MDA5). Polyinosinic-polycytidylic acid can be used as a vaccine adjuvant to enhance innate and adaptive immune responses, and to alter the tumor microenvironment. Polyinosinic-polycytidylic acid can directly trigger cancer cells to undergo apoptosis .

HY-D1327

Cyanine3 azide chloride

1 Publications Verification

Fluorescent Dyes/Probes

Cyanine3 azide chloride, an analog of Cy3 azide, is a potent green fluorescent dye. Cyanine3 azide chloride uses click chemistry coupled with Alkyne-labeled proteins. Cyanine3 azide chloride can be detected by fluorometers, imagers, and microscopes. (λ_ex=684 nm, λ_em=710 nm) ^[1]. Cyanine3 azide (chloride) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-43520

BODIPY-FL

Fluorescent Dyes/Probes

BODIPY-FL is a green fluorescent dye that can be used to label probes or primers. BODIPY-FL fluorescence can be quenched after interacting with uniquely positioned guanine, making it useful for quantifying specific DNA or RNA molecules. BODIPY-FL-labeled sphingolipid analogs can be used to investigate sphingolipid internalization, transport, and endocytosis in mouse embryonic stem cells. BODIPY-FL-labeled monoterpenes can quickly penetrate bacteria, mammalian, and fungal cells, allowing for the detection of characteristics of a broad spectrum of Gram-positive and Gram-negative bacteria, as well as pathogenic fungi. The maximum absorption wavelength of BODIPY-FL is 505 nm, and the maximum emission wavelength is 513 nm .

Cat. No.	Product Name	Type

HY-21586B

7-Methyl-guanosine-5'-triphosphate sodium m7GTP sodium	Gene Sequencing and Synthesis
7-Methyl-guanosine-5'-triphosphate (m7GTP) sodium is a guanosine 5'-phosphate. 7-Methyl-guanosine-5'-triphosphate sodium phosphorothioate analog is a potent cap-dependent translation inhibitor .

HY-W104379

Arprinocid	Cell Assay Reagents
Arprinocid is a purine analog with activity against murine Toxoplasma gondii .

HY-W110888

Brilliant Yellow	Biochemical Assay Reagents
Brilliant Yellow, a diazo-containing sulfonic aci, is also a potent VGLUT-specific inhibitor. Brilliant Yellow is membrane-impermeable. However, there are some Brilliant Yellow analogs with low cytotoxicity and cell penetration. Brilliant Yellow analogs work on glutamatergic transmission in hippocampal neurons .

HY-W127851

CLA

Cypridina luciferin Analog

Biochemical Assay Reagents

CLA, or conjugated linoleic acid, is a polyunsaturated fatty acid that occurs naturally in a variety of animal products, such as meat and dairy. It has several potential benefits for human health, including the ability to reduce body fat mass, improve insulin sensitivity, and reduce inflammation. CLA has been extensively studied for its effects on weight loss and muscle growth, as well as its potential role in preventing chronic diseases such as heart disease and cancer. Additionally, it can be taken as a dietary supplement in capsule form.

HY-139101

Guanosine 5'-triphosphate-5'-adenosine GpppA	Gene Sequencing and Synthesis
Guanosine 5'-triphosphate-5'-adenosine (GpppA), a 5′ cap analog, can be used for RNA synthesis in vitro. Guanosine 5'-triphosphate-5'-adenosine is a fluorescent substrate analog .

HY-150144

Uracil-m7GpppAmpG ammonium	Gene Sequencing and Synthesis
Uracil-m7GpppAmpG ammonium is a cap analog that can be used for mRNA synthesis.

HY-145977A

m7GpppGmpG ammonium	Gene Sequencing and Synthesis
m7GpppGmpG ammonium is a trinucleotide 5′ cap analog with the capping efficiencies for the obtained RNAs of 86% .

HY-W854345

3-Deoxy-D-glucose	Carbohydrates
3-Deoxy-D-glucose, a carbohydrate, is an analog of D-Glucose (HY-B0389) .

HY-W357106

3-O-Benzyl-1,2:5,6-di-O-isopropylidene-a-D-allofuranose 1,2:5,6-di-O-Isopropylidene-3-O-benzyl-α-D-allofuranose	Carbohydrates
3-O-Benzyl-1,2:5,6-di-O-isopropylidene-a-D-allofuranose is a nucleoside analog.

HY-132143

7-Deaza-7-propargylamino-dATP	Gene Sequencing and Synthesis
7-Deaza-7-propargylamino-dATP is an analog of deoxyadenosine triphosphate (dATP) that can be used for gene sequencing .

HY-132147

7-Deaza-7-propargylamino-ddATP	Gene Sequencing and Synthesis
7-Deaza-7-propargylamino-ddATP is an analog of dideoxyadenosine triphosphate (ddATP) that can be used for gene sequencing .

HY-132148

7-Deaza-7-propargylamino-ddGTP	Gene Sequencing and Synthesis
7-Deaza-7-propargylamino-ddGTP is an analog of dideoxyguanosine triphosphate (ddGTP) that can be used for gene sequencing .

HY-132144

7-Deaza-7-propargylamino-dGTP	Gene Sequencing and Synthesis
7-Deaza-7-propargylamino-dGTP is an analog of deoxyguanosine triphosphate (dGTP) that can be used for gene sequencing .

HY-W337897

Tetradecyl-β-D-maltoside	Biochemical Assay Reagents
Tetradecyl-β-D-maltoside is an absorption enhancer which can increase the nasal absorption of regular human insulin or the fast acting insulin analog lyspro-insulin .

HY-W394106

5-Hydroxymethyl uridine	Biochemical Assay Reagents
5-Hydroxymethyl uridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .

HY-132140

7-Deaza-7-propargylamino-3'-azidomethyl-dGTP	Gene Sequencing and Synthesis
7-Deaza-7-propargylamino-3'-azidomethyl-dGTP is an analog of deoxyguanosine triphosphate (dGTP) that widely used in the next generation sequencing (NGS) .

HY-132139

7-Deaza-7-propargylamino-3'-azidomethyl-dATP	Gene Sequencing and Synthesis
7-Deaza-7-propargylamino-3'-azidomethyl-dATP is an analog of deoxy adenosine triphosphate (dATP) that widely used in the next generation sequencing (NGS) .

HY-131485

3-Acetylpyridine adenine dinucleotide, 90% 3-APAD, 90%; 3-Acetylpyridine NAD, 90%	Gene Sequencing and Synthesis
3-Acetylpyridine adenine dinucleotide, 90% is an analog of nicotinamide adenine dinucleotide (NAD). 33-Acetylpyridine adenine dinucleotide, 90% collaboratively inhibits Lactate Dehydrogenase (LDH) with bisulfite .

HY-148851

Bacteriochlorophyll a, from Rhodopseudomonas sphaeroides (under argon) BChl a, from Rhodopseudomonas sphaeroides (under argon)	Indicators
Bacteriochlorophyll a, from Rhodopseudomonas sphaeroides (under argon) (BChl a, from Rhodopseudomonas sphaeroides (under argon)) is a chlorophyll analog found in some bacteria that participates in the light absorption and energy transfer processes of photosynthesis .

HY-118563

Farnesylthioacetic acid	Biochemical Assay Reagents
S-Farnesyl thioacetic acid is an analog of S-farnesyl cysteine, which is a prenylated protein methyltransferase (also known as S-adenosylmethionine-dependent methyltransferase) competitive inhibitors. It also inhibits the methylation of farnesylated and geranylgeranylated substrates.

HY-145975A

m7Gpppm6AmpG (ammonium) solution (100mM)	Gene Sequencing and Synthesis
m7Gpppm6AmpG ammonium solution (100mM) is a trinucleotide mRNA 5’ cap analogs. m7Gpppm6AmpG ammonium can be used for RNA synthesis in vitro .

HY-139100

N7-Methyl-guanosine-5'-triphosphate-5'-adenosine m7GpppA	Gene Sequencing and Synthesis
N7-Methyl-guanosine-5'-triphosphate-5'-adenosine (m7GpppA) is a dinucleotide cap analog that can be used for in vitro RNA transcription .

HY-139098

7-Methyl-diguanosine triphosphate m7Gp3G	Gene Sequencing and Synthesis
7-Methyl-diguanosine triphosphate (m7Gp3G) is a cap analog that can incorporated into mRNA. 7-Methyl-diguanosine triphosphate is involved in translation and mRNA degradation in mammalian cells .

HY-131485A

3-Acetylpyridine adenine dinucleotide, 95% 3-APAD, 95%; 3-Acetylpyridine NAD, 95%	Gene Sequencing and Synthesis
3-Acetylpyridine adenine dinucleotide, 95% (3-APAD, 95%)is an analog of nicotinamide adenine dinucleotide (NAD). 33-Acetylpyridine adenine dinucleotide, 95% collaboratively inhibits Lactate Dehydrogenase (LDH) with bisulfite .

HY-W039920

1-Amino-1-deoxy-β-D-galactose, 98% β-D-Galactosylamine, 98%	Carbohydrates
1-Amino-1-deoxy-β-D-galactose, 98% is a galactose analog used as a competitive inhibitor to aid in the separation, purification, identification, differentiation, and characterization of β-D-galactosidase and galactose oxidase.

HY-59273

5-Nitroindole	Biochemical Assay Reagents
5-Nitroindole is a mutagenic nitroarene and universal base analog. 5-Nitroindole significantly reduces the cellular adenylate energy charge by decreasing ATP levels and increasing AMP levels. 5-Nitroindole inhibits lipid peroxidation .

HY-137697

ddCTP	Gene Sequencing and Synthesis
ddCTP is one of 2',3'-dideoxyribonucleoside 5'-triphosphates (ddNTPs) that acts as chain-elongating inhibitor of DNA polymerase for DNA sequencing. ddCTP is a nucleoside analog that targets the reverse transcriptase of HIV. ddCTP can be used for AIDS research .

HY-155743A

ddUTP (lithium), 100mM in H2O 2',3'-Dideoxyuridine-5'-triphosphate lithium	Gene Sequencing and Synthesis
ddUTP (lithium), 100mM in H₂O is a nucleotide analog that can be incorporated into DNA, RNA, or other nucleic acids. ddUTP (lithium), 100mM in H₂O can be used to prepare DNA/RNA hybridization experiments, such as Southern blots and Northern blots.

HY-W010488

Dithiooxamide	Biochemical Assay Reagents
Dithiooxamide (Rubeanic Acid) is a selective chelating agent and sulfur-containing analog of Oxamide. Dithiooxamide forms stable chelates with various metal ions (such as lead, iron, cadmium, manganese, and aluminum), which can be separated, enriched, and detected by adsorption on solid adsorbents or electrode surfaces .

HY-W791727

7-Methyladenosine perchlorate	Gene Sequencing and Synthesis
7-Methyladenosine perchlorate is a synthetic analog of adenosine with agonist activity at adenosine receptors. 7-Methyladenosine perchlorate is able to modulate cell signaling and is useful for studying adenosine-related biological processes. 7-Methyladenosine perchlorate can be used as a potential inhibitor in compound development.

HY-142028A

Acyclovir triphosphate sodium AcycloGTP sodium	Gene Sequencing and Synthesis
Acyclovir triphosphate (Synonyms: AcycloGTP) sodium is a Acyclovir (HY-17422) derivative that competitively inhibits viral DNA polymerase by acting as an analog to deoxyguanosine triphosphate (dGTP). Acyclovir triphosphate sodium is an inhibitor of HIV-1 reverse transcriptase. Acyclovir triphosphate sodium causes termination of viral DNA synthesis .

HY-19997

Mannose triflate TATM	Carbohydrates
Mannose triflate is a glucose analog. Mannose triflate is a precursor for 18F-FDG synthesis for PET applications. Mannose triflate binds to 18F via SN2 nucleophilic substitution reaction. Mannose triflate can be used for an imaging technique in detection of cancer .

HY-W008888

N-Xantphos 4,6-Bis(diphenylphosphino)phenoxazine	Biochemical Assay Reagents
N-Xantphos (4,6-Bis(diphenylphosphino)phenoxazine) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. N-Xantphos is a functionalized analog of the Xantphos ligand. N-Xantphos can be used as supporting ligand for Pd-mediated carbonylation .

HY-W001974

7-Nitroindole	Biochemical Assay Reagents
7-Nitroindole is a cleavable base analog. 7-nitroindole nucleoside is a photochemical precursor, which is used to specifically generate 2'-deoxyribonolactone oxidative damage sites in DNA strands. 7-Nitroindole can be used for the study of photo-controlled DNA breakage tools .

HY-W001992

2,6-Dichloro-3-nitropyridine 3-Nitro-2,6-dichloropyridine	Biochemical Assay Reagents
2,6-Dichloro-3-nitropyridine is a starting compound for the synthesis of a sulfide analog of Flupirtine (HY-17001A) with KV7.2/3 channel opening activity. 2,6-Dichloro-3-nitropyridine can be used in pain research .

HY-117115

1,2-Dihexanoyl-sn-glycerol	Drug Delivery
1,2-Dihexanoyl-sn-glycerol is an analog of protein kinase C (PKC) that activates the second messenger diacylglycerol (DAG). Although the biological activity of 1,2-dicaproyl-sn-glycerol has not been well characterized, it is expected to behave similarly to 1,2-dioctanoyl-sn-glycerol.

HY-W700460

9-β-D-Arabinofuranosyl-2-fluorohypoxanthine	Gene Sequencing and Synthesis
9-β-D-Arabinofuranosyl-2-fluorohypoxanthine is a nucleoside analog with activity as an inhibitor of certain enzymes. 9-β-D-Arabinofuranosyl-2-fluorohypoxanthine is useful in synthesis and, due to its structural changes, is able to cause base mispairing, thereby stopping chain polymerization reactions.

HY-W127502

1-Hexadecyl lysophosphatidic acid 1-Hexadecyl LPA; 1-Palmityl LPA; LPA O-16:0	Cell Assay Reagents
1-Hexadecyl lysophosphatidic acid is an ether analog of lysophosphatidic acid (LPA) containing a hexadecyl group in the sn-1 position. LPA binds to five different G protein-coupled receptors and mediates a variety of biological responses, including cell proliferation, smooth muscle contraction, platelet aggregation, neurite contraction, and cell motility.

HY-118667

Dehydroergosterol	Native Proteins
Dehydroergosterolis a naturally occurring fluorescent sterol analog (Ex/Em=325/375 nm), which mimics the properties of cholesterol in cell membranes. DehydroergosterolEasily conjugated by cholesterol-binding proteins for real-time imaging in live cells. DehydroergosterolThe sterol environment and intracellular sterol transport in vivo can be probed/elucidated in real time .

HY-174916

Amine-PEG1-Desthiobiotin	Drug Delivery
Amine-PEG1-Desthiobiotin is a PEG derivative consisting of desthiobiotin, 1 PEG unit, and an amino group (Amine). Desthiobiotin is a biotin analog that has a weak but reversible binding ability to streptavidin or avidin. The amino group is able to react with other chemical groups (such as carboxyl, aldehyde, etc.) to form stable chemical bonds.

HY-132144A

7-Deaza-7-propargylamino-dGTP sodium	Gene Sequencing and Synthesis
7-Deaza-7-propargylamino-dGTP sodium is the sodium salt form of 7-Deaza-7-propargylamino-dGTP (HY-132144). 7-Deaza-7-propargylamino-dGTP sodium is an analog of deoxyguanosine triphosphate dGTP (HY-W008661) and can be used for gene sequencing .

HY-W008213

2-Chloro-5-methylbenzoic acid	Biochemical Assay Reagents
2-Chloro-5-methylbenzoic acid can be used to synthesize amide when coupled with 1-Adamantylmethanamine. 2-Chloro-5-methylbenzoic acid can also give analog when coupled with an amine using EDC hydrochlorie and Et₃N in anhydrous CH₂Cl₂ .

HY-129038

GR24 Strigolactone GR24	Cell Assay Reagents
(Rac)-GR24 (Strigolactone GR24) is a plant hormone analog. (Rac)-GR24 can mimic the natural germination stimulus of parasitic plant seeds, promoting seed germination in the absence of host plants, thereby reducing the number of parasitic seeds in the soil. (Rac)-GR24 can be used in agricultural research .

HY-W152363

1,2,3,4-Tetra-O-acetyl-alpha-L-fucopyranose

1,2,3,4-Tetra-O-acetyl-α-L-fucopyranose

Carbohydrates

1,2,3,4-Tetra-O-acetyl-alpha-L-fucopyranoseIt is an organic compound commonly used as a substrate or reference standard in enzymology and sugar chemistry research. It can be used in the synthesis of polysaccharide analogs, drug development and biotechnology, and is widely used in the research of glycosyl chemistry and sugar metabolism pathways. In addition, this compound is used as a catalyst or buffer in certain biochemical reactions.

HY-153108

3'-O-Me-m7G(5')ppp(5')A solution (100mM) ARCA cap solution (100mM)	Biochemical Assay Reagents
3'-O-Me-m7G(5')ppp(5')A (ARCA cap) solution (100mM), anti-reverse cap analog, has a special RNA cap structure. Is a common feature of the mRNA of some RNA viruses and eukaryotes. RNA cap structures serve as signals for translation initiation .

HY-167820

3-Ketosphingosine

Drug Delivery

3-Ketosphingosine trifluoroacetate is a chemically modified sphingomyelin analog with specific enzymatic pathway research activity. It is mainly used to explore the functions of sphingomyelin kinases and lyases in sphingomyelin metabolism. 3-Ketosphingosine trifluoroacetate has important application value in the study of cell signal transduction and related diseases. The study of 3-Ketosphingosine trifluoroacetate helps to deepen the understanding of sphingomyelin-related biological processes.

HY-W015467

Pyridine-3-sulfonic acid Pyridine-3-sulphonic acid	Biochemical Assay Reagents
Pyridine-3-sulfonic acid (Pyridine-3-sulphonic acid) is an orally active structural analog of Nicotine acid (HY-B0143). Pyridine-3-sulfonic acid significantly reduces hepatic cholesterol synthesis in rats but lacks cholesterol-lowering activity. Pyridine-3-sulfonic acid does not interfere with the metabolism of Nicotine acid .

HY-D0177

(Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate

Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate

Biochemical Assay Reagents

(Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate (Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate) is a peptide coupling reagent and BOP analog. (Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate promotes the reaction of amino and carboxyl groups to form peptide bonds. (Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate can be used in the synthesis of peptide compounds

HY-130777A

AMP-PNP lithium hydrate

3 Publications Verification

Adenylyl imidodiphosphate lithium hydrate

Gene Sequencing and Synthesis

AMP-PNP (Adenylyl imidodiphosphate) lithium hydrate is a non-hydrolyzable ATP analog. AMP-PNP lithium hydrate binds to ATP binding sites competely but is not hydrolyzed by enzymes, providing stable experimental conditions for studying ATP-dependent processes. AMP-PNP lithium hydrate can also be used to study enzyme activity, kinase regulation, DNA/RNA metabolism, ion channel function, and protein complex assembly .

HY-32813

2-Amino-3-iodopyridine 1 Publications Verification 3-Iodopyridin-2-amine	Biochemical Assay Reagents
2-Amino-3-iodopyridine (3-Iodopyridin-2-amine) can be coupled with formyl derivatives under a copper-catalyzed indole synthesis method, and then constructed azide analogs through copper-mediated conjugated adducts things. The nucleophilicity of 2-Amino-3-iodopyridine is lower than that of the corresponding aniline used in the synthesis of indole, a potential obstacle for future synthesis .

Cat. No.	Product Name	Target	Research Area

HY-P99428

Aldafermin NGM282	Inhibitory Antibodies	Metabolic Disease
Aldafermin (NGM282) is an analog of fibroblast growth factor 19. Aldafermin can be used for the research of nonalcoholic steatohepatitis (NASH) .

HY-118860

Corifollitropin alfa Org 36286; MK-8962	Estrogen Receptor/ERR	Endocrinology
Corifollitropin alfa (Org 36286) is a long-acting recombinant follicle-stimulating hormone (FSH) analog. Corifollitropin alfa is a FSH Receptor agonist with an EC₅₀ of 5.0 pM. Corifollitropin alfa stimulates ovulation and can be used in the research of infertility .

HY-P990967

Sonefpeglutide	GLP Receptor	Inflammation/Immunology
Sonefpeglutide is a long-acting glucagon-like peptide 2 (GLP-2) analog .

HY-119810A

Seletracetam lithium Ucb 44212 lithium	HIV	Neurological Disease
Seletracetam (Ucb 44212) lithium, as an analog of the antiepileptic agent Levetiracetam, is a SV2A modulator for the research of epilepsy .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-P1902

*Cardiotoxin Analog* (CTX) IV (6-12)** 5+ Cited Publications	Cardiovascular Disease Natural Products Animals Source classification Disease Research Fields	Apoptosis
Cardiotoxin Analog (CTX) IV (6-12) is a membrane active peptide that specifically targets negatively charged phospholipid membranes (such as phosphatidylserine and phosphatidylinositol) and can be isolated from the venom of the Taiwan cobra. Cardiotoxin Analog (CTX) IV (6-12) is a snake venom cardiotoxin that binds to cell membranes and embeds into lipid bilayers through hydrophobic interactions and electrostatic attraction, thereby destroying the stability of membrane structure. Cardiotoxin Analog (CTX) IV (6-12) can induce membrane lipid disorder and cell lysis, exhibiting hemolysis and cytotoxicity .

HY-P1902A

*Cardiotoxin Analog* (CTX) IV (6-12) TFA** 5+ Cited Publications	Pyrrole Alkaloids Animals Source classification Other Diseases Disease Research Fields	Apoptosis
Cardiotoxin Analog (CTX) IV (6-12) TFA is a membrane active peptide that specifically targets negatively charged phospholipid membranes (such as phosphatidylserine and phosphatidylinositol) and can be isolated from the venom of the Taiwan cobra. Cardiotoxin Analog (CTX) IV (6-12) TFA is a snake venom cardiotoxin that binds to cell membranes and embeds into lipid bilayers through hydrophobic interactions and electrostatic attraction, thereby destroying the stability of membrane structure. Cardiotoxin Analog (CTX) IV (6-12) TFA can induce membrane lipid disorder and cell lysis, exhibiting hemolysis and cytotoxicity .

HY-W012313

2,2'-Anhydrouridine 2,2'-Cyclouridine; O2,2'-Cyclouridine	Infection Classification of Application Fields Disease Research Fields	Drug Intermediate Nucleoside Antimetabolite/Analog
2,2'-Anhydrouridine (2,2'-Cyclouridine) is a nucleoside analog. 2,2'-Anhydrouridine is an important intermediate in the synthesis of other nucleoside-related compounds .

HY-59132

2-Amino-1-phenylethanol	Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite Drug Intermediate
2-Amino-1-phenylethanol is a Norepinephrine (HY-13715) analog. 2-Amino-1-phenylethanol derivatives exhibit antimalarial activity against Plasmodium falciparum .

HY-118384

Sangivamycin 3 Publications Verification NSC 65346; BA-90912	Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields Cancer	PKC Nucleoside Antimetabolite/Analog
Sangivamycin (NSC 65346), a nucleoside analog, is a potent inhibitor of protein kinase C (PKC) with an K_i of 10 μM. Sangivamycin has potent antiproliferative activity against a variety of human cancers .

HY-N10492

*Spongionellol A analog* 1**	Microorganisms Source classification Diterpenoids	P-glycoprotein
Spongionellol A analog 1, an analog of Spongionellol A (HY-10491), is a MDR1 (p-glycoprotein) inhibitor. Spongionellol A analog 1 has high cytotoxic activity and selectivity in prostate cancer cells by inducing caspase?dependent apoptosis. Spongionellol A analog 1 can be used in the research of cancers, such as prostate cancer .

HY-N15785

18:0-Azo PC	Lipid	Biochemical Assay Reagents
18:0-azo PC is an analog of phosphatidylcholine (PC). Under light, 18:0-azo PC can be switched on and off by light, forcing the azobenzene portion of the molecule to undergo cis/trans isomerization, leading to the initiation or termination of cell signaling.

HY-N8488

Anhydro-6-epiophiobolin A	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Disease Research Fields	Others
Anhydro-6-epiophiobolin A, an analog of Ophiobolin A, is a potent inhibitor of photosynthesis (I₅₀s of 6.1 and 1 mM for photosynthesis in Chlorella and Spinach, respectively) .

HY-N0449R

Nordihydrocapsaicin (Standard)	Alkaloids Monophenols Capsicum annuum L. Other Alkaloids Source classification Phenols Solanaceae Plants	Reference Standards Others
Nordihydrocapsaicin (Standard) is the analytical standard of Nordihydrocapsaicin. This product is intended for research and analytical applications. Nordihydrocapsaicin is a capsaicinoid analog and congener of capsaicin in chili peppers .

HY-N15873

XY-69 triethylamine	Lipid	Biochemical Assay Reagents
XY-69 triethylamine is a fluorescent analog of PIP2. XY-69 liposomal assay can be utilized in monitoring PLC enzymatic activity .

HY-W016509

epi-Inositol	Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Drug Derivative
epi-Inositol, a inositol analog, is an antidepressant agent. epi-Inositol shows regulatory effects on expression of the most highly regulated gene in the inositol biosynthetic pathway. epi-Inositol shows antiepileptic effect .

HY-W091784

3'-O-Methylguanosine	Infection Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite Orthopoxvirus Nucleoside Antimetabolite/Analog DNA/RNA Synthesis
3'-O-Methylguanosine is a methylated nucleoside analog and RNA chain terminator. 3'-O-Methylguanosine can inhibit the synthesis of early vaccinia virus-specific RNA .

HY-N0449

Nordihydrocapsaicin	Alkaloids Monophenols Capsicum annuum L. Classification of Application Fields Other Alkaloids Source classification Other Diseases Phenols Solanaceae Plants Disease Research Fields	NADPH Oxidase Keap1-Nrf2
Nordihydrocapsaicin, an analog of Capsaicin (HY-10448), is an orally active compound with pungent properties and anti-cancer activities, which is found in fresh and processed peppers. Nordihydrocapsaicin can cause a burning sensation when consumed .

HY-118384R

Sangivamycin (Standard) NSC 65346 (Standard); BA-90912 (Standard)	Natural Products Microorganisms Source classification	Reference Standards PKC Nucleoside Antimetabolite/Analog
Sangivamycin (Standard) is the analytical standard of Sangivamycin. This product is intended for research and analytical applications. Sangivamycin (NSC 65346), a nucleoside analog, is a potent inhibitor of protein kinase C (PKC) with an Ki of 10 μM. Sangivamycin has potent antiproliferative activity against a variety of human cancers[1][2].

HY-77554

Cephalomannine	Classification of Application Fields Terpenoids Taxaceae Source classification Diterpenoids Plants Disease Research Fields Taxus chinensis (Pilger) Rehd. Cancer	Microtubule/Tubulin HIF/HIF Prolyl-Hydroxylase
Cephalomannine is a Paclitaxel (HY-B0015) alkaloidal analog that can be isolated from most Cephalotaxus species. Cephalomannine is an orally active anti-tumor agent and can be used as a chemotherapy agent for cancer research .

HY-W006371

(2-Aminoethyl)phosphonic acid	Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite Drug Intermediate
(2-Aminoethyl)phosphonic acid is an endogenous metabolite and amino acid analog. (2-Aminoethyl)phosphonic acid can be used for the synthesis of biological macromolecules and the preparation of hydrogels .

HY-125396

11-Deoxyprostaglandin F2β 11-Deoxy-PGF2β	Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
11-Deoxyprostaglandin F2β (11-deoxy PGF2β) is an analog of PGF2β (HY-12956B). PGF2β is a metabolite produced by cyclooxygenase metabolism of arachidonic acid. PGF2β induces dose-dependent release of hexose containing mucin .

HY-77554R

Cephalomannine (Standard)	Terpenoids Taxaceae Source classification Diterpenoids Plants Taxus chinensis (Pilger) Rehd.	Microtubule/Tubulin HIF/HIF Prolyl-Hydroxylase Reference Standards
Cephalomannine (Standard) is the analytical standard of Cephalomannine. This product is intended for research and analytical applications. Cephalomannine is a Paclitaxel (HY-B0015) alkaloidal analog that can be isolated from most Cephalotaxus species. Cephalomannine is an orally active anti-tumor agent and can be used as a chemotherapy agent for cancer research .

HY-W091784R

3'-O-Methylguanosine (Standard)	Natural Products Source classification Endogenous metabolite	Reference Standards Endogenous Metabolite Orthopoxvirus Nucleoside Antimetabolite/Analog DNA/RNA Synthesis
3'-O-Methylguanosine (Standard) is an analytical standard of 3'-O-Methylguanosine (HY-W091784). This product is intended for research and analytical applications. 3'-O-Methylguanosine is a methylated nucleoside analog and RNA chain terminator. 3'-O-Methylguanosine can inhibit the synthesis of early vaccinia virus-specific RNA .

HY-N16377

1-Butyl-3,5,8-trihydroxy-9,10-anthracenedione	Quinones Microorganisms Anthraquinones Source classification	Others
1-Butyl-3,5,8-trihydroxy-9,10-anthracenedione (Compound 2) is an anthraquinone analog. 1-Butyl-3,5,8-trihydroxy-9,10-anthracenedione can be isolated from soil Actinomycete Streptomyces. 1-Butyl-3,5,8-trihydroxy-9,10-anthracenedione has potent cytotoxicity against HepG2, A875, BGC-823 and MCF-7 cells with IC₅₀s of 2.29, 4.90, 0.99 and 1.66 μg/mL, respectively. 1-Butyl-3,5,8-trihydroxy-9,10-anthracenedione has an antitumor activity .

HY-N2375

L-Quebrachitol	Natural Products other families Classification of Application Fields Source classification Metabolic Disease Plants Disease Research Fields	Wnt β-catenin p38 MAPK
L-Quebrachitol is a methoxy analog of inositol that can be isolated from plants. L-Quebrachitol has free-radical scavenging, gastroprotection, anti-platelet aggregation and anti-diabetic activity. L-Quebrachitol promotes osteoblastogenesis by uppregulation of BMP-2, runt-related transcription factor-2 (Runx2), MAPK (ERK, JNK, p38α), and Wnt/β-catenin signaling pathway .

HY-N2375R

L-Quebrachitol (Standard)	Natural Products other families Source classification Plants	Wnt β-catenin p38 MAPK
L-Quebrachitol is a methoxy analog of inositol that can be isolated from plants. L-Quebrachitol has free-radical scavenging, gastroprotection, anti-platelet aggregation and anti-diabetic activity. L-Quebrachitol promotes osteoblastogenesis by uppregulation of BMP-2, runt-related transcription factor-2 (Runx2), MAPK (ERK, JNK, p38α), and Wnt/β-catenin signaling pathway .

HY-123724

Ravidomycin	Monophenols Microorganisms Source classification Phenols	Others
Ravidomycin is a compound with antibacterial and cytotoxic activities. New analogs have been isolated from microorganisms. These analogs differ in antibacterial selectivity compared with known compounds.

HY-103191

1,9-Dideoxyforskolin	Terpenoids Labiatae Source classification Diterpenoids Plants Pueraria montana (Lour.) Merr.	Adenylate Cyclase
1,9-Dideoxyforskolin is an inactive analog of forskolin .

HY-122324

Tylophorine (+)-(S)-Tylophorine; DCB-3500; NSC-717335	Apocynaceae Source classification Plants Tylophora	Others
Tylophorine and its analogs are benzoindole alkaloids, most of which are derived from Garcinia plants. Tylophorine analogs all show potent growth inhibition against human hepatocellular carcinoma HepG2 and human nasopharyngeal carcinoma KB cell lines. Tylophorine analogs can also induce increased albumin expression and inhibit α-fetoprotein expression in HepG2 cells, and have the potential to induce HepG2 cell differentiation .

HY-N14164

Echinoserine	Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial
Echinoserine is an analog of Echinomycin (HY-106101) with antibacterial activity .

HY-103273

Muristerone A	Ipomoea nil (Linnaeus) Roth Classification of Application Fields Source classification Other Diseases Plants Convolvulaceae Disease Research Fields Steroids	Endogenous Metabolite
Muristerone A is a phytoecdysteroid analog of ecdysone and a potent agonist of ecdysteroid receptor with a K_d of 1 nM .

HY-59132R

2-Amino-1-phenylethanol (Standard)	Natural Products Source classification Endogenous metabolite	Endogenous Metabolite Drug Intermediate
2-Amino-1-phenylethanol (Standard) is the analytical standard of 2-Amino-1-phenylethanol. This product is intended for research and analytical applications. 2-Amino-1-phenylethanol is an analogue of noradrenaline.

HY-103248

Toyocamycin 5+ Cited Publications Vengicide	Infection Microorganisms Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Disease Research Fields Other Antibiotics	IRE1 Fungal Antibiotic Apoptosis CDK
Toyocamycin (Vengicide) is an adenosine analog produced by Streptomyces diastatochromogenes, acts as an XBP1 inhibitor. Toyocamycin blocks RNA synthesis and ribosome function, and induces apoptosis. Toyocamycin affects IRE1α-XBP1 pathway, and inhibits XBP1 mRNA cleavage with an IC₅₀ value of 80 nM with affecting IRE1α auto-phosphorylation. Toyocamycin specifically inhibits CDK9 with an IC₅₀ value of 79 nM .

HY-W005627

Linoleyl alcohol	Natural Products other families Classification of Application Fields Source classification Metabolic Disease Plants Disease Research Fields	Drug Derivative
Linoleyl alcohol, a structural analog of Linoleic acid with no a-carboxyl group, is a fatty alcohol .

HY-116007

Gaxilose	Microorganisms Source classification Saccharides Monosaccharides	Drug Derivative
Gaxilose is a synthetic lactose analog that can used as a diagnostic tool to detect hypolactasia .

HY-112639

Aristeromycin	Infection Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields	Antibiotic Bacterial
Aristeromycin, an adenosine analog, is an antibiotic and a potent S-adenosylhomocysteine hydrolase (AHCY) inhibitor .

HY-125070

Saframycin C	Microorganisms Antibiotics Source classification Disease Research	Antibiotic
Racemomycin C is an analog of the antibiotic soramycin and is probably the 0-methyl derivative of racemomycin B.

HY-N3882

Eurycarpin A	Flavonoids Source classification Plants Crotalaria ferruginea Grah. ex Benth. Isoflavones Fabaceae	Others
Eurycarpin A is isoflavonoid analog isolated from the ethanol extract of the Chinese folk medicine Crotalaria ferruginea .

HY-114673

Benzomalvin B	Alkaloids Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Source classification Other Diseases Quinoline Alkaloids Endogenous metabolite Disease Research Fields	Neurokinin Receptor
Benzomalvin B is the less active analogs of Benzomalvin A. Benzomalvin B is weakly active against substance P .

HY-W015424

N-Methyl-DL-glutamic acid 1 Publications Verification	Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
N-Methyl-DL-glutamic acid is a L-Glutamic acid (HY-14608) analog with cytotoxic effects .

HY-W015424R

N-Methyl-DL-glutamic acid (Standard)	Natural Products Source classification Endogenous metabolite	Endogenous Metabolite
N-Methyl-DL-glutamic acid is a L-Glutamic acid (HY-14608) analog with cytotoxic effects .

HY-N13984

Arylomycin B5	Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial
Arylomycin B5, a microbial metabolite, is a structural analog of Arylomycin B2 (HY-N13981) .

HY-125699

Ochratoxin C	Infection Natural Products Monophenols Microorganisms Classification of Application Fields Source classification Phenols Disease Research Fields	Fungal
Ochratoxin C is the ethyl ester analog of ochratoxin A, a mycotoxin produced by A. ochraceus, A. carbonarius, and P. verrucosum that is commonly found as a food contaminant.

HY-126708

Luisol A	Infection Natural Products Monophenols Microorganisms Classification of Application Fields Source classification Marine natural products Phenols Disease Research Fields Marine microorganism	ADC Payload Antibiotic
Luisol A, an aromatic tetraol, is a major metabolite of an estuarine marine actinomycete of the genus Streptomyces. Luisol A, is an anthraquinone antibiotic analog ^.

HY-N13982

Arylomycin B3	Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial
Arylomycin B3, a microbial metabolite, is a structural analog of Arylomycin B2 (HY-N13981) .

HY-139568

Deutarserine CTP-692	Neurological Disease Classification of Application Fields Source classification Amino acids Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Deutarserine is a deuterium modified analog of endogenous D-serine (CTP 692), which is used in the research of adults with schizophrenia .

HY-130072

Bivittoside B	Polysaccharides Animals Source classification Saccharides	Fungal
Bivittoside B is a non-sulfated hexoside analog derived from Bovine sea cucumber, exhibiting antifungal and potential antitumor activities.

HY-130047

Bivittoside A	Polysaccharides Animals Source classification Saccharides	Fungal
Bivittoside A is a non-sulfated hexoside analog derived from Bovine sea cucumber, exhibiting antifungal properties and potential for antitumor applications.

HY-77434

9-Dihydro-13-acetylbaccatin III 9-DHAB III; 13-Acetyl-9-dihydrobaccatin III	Classification of Application Fields Terpenoids Taxaceae Source classification Diterpenoids Plants Disease Research Fields Taxus chinensis (Pilger) Rehd. Cancer	Drug Intermediate
9-Dihydro-13-acetylbaccatin III (9-DHAB III) is an intermediate for the preparation of paclitaxel analogs.

HY-N8488A

Anhydroophiobolin A	Classification of Application Fields Other Diseases Disease Research Fields	Others
Anhydroophiobolin A is a potent inhibitor of photosynthesis with IC₅₀s of 77 and 14 mM in the photosynthesis of chlorella and spinach, respectively. Anhydroophiobolin A is an analog of Ophiobolin A .

HY-123706

Salinosporamide C	Microorganisms Ketones, Aldehydes, Acids Source classification	Endogenous Metabolite
Salinosporamide C (compound 4) is a decarboxylated pyrrole analog. Salinosporamide C is the secondary metabolite of the obligate marine actinomycete Salinispora tropical .

HY-N15368

Pradimicinone I	Quinones Microorganisms Anthraquinones Source classification	Antibiotic Bacterial
Pradimicinone I (Compound 10), a Pradimicin A (HY-132191) analog, is an antibiotic. Pradimicinone I is promising for research of antibacterial agents .

HY-N13925

Arisugacin E	Natural Products Microorganisms Source classification	Cholinesterase (ChE)
Arisugacin E, a microbial metabolite, is a structural analog of Arisugacin A (HY-N13901). Arisugacin E shows no activity against AChE .

HY-N13927

Arisugacin G	Natural Products Microorganisms Ketones, Aldehydes, Acids Source classification	Cholinesterase (ChE)
Arisugacin G, a microbial metabolite, is a structural analog of Arisugacin A (HY-N13901). Arisugacin G shows no activity against AChE .

Cat. No.	Product Name	Chemical Structure

HY-13311S

Infigratinib-d3
Infigratinib-d3 is a deuterated analog of infigratinib. Infigratinib is an effective inhibitor of the FGFR family, with IC₅₀ values of 0.9 nM, 1.4 nM, 1 nM, and 60 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively .

HY-W654077

Bisphenol AF-d4
Bisphenol AF-d₄ is the isotope labelled analog of Bisphenol AF (HY-W013782). Bisphenol AF is a full agonist for the estrogen receptor. Bisphenol AF acts as an endocrine-disrupting chemical (EDC), activating estrogen through the estrogen receptor Era. Bisphenol AF-d₄ can be used for the research of endocrinology and cancer .

HY-156756S

7-Hydroxymethyl-10,11-MDCPT-d5
7-Hydroxymethyl-10,11-MDCPT-d₅ is deuterium labeled 7-Hydroxymethyl-10,11-MDCPT, which is a is a payload that can be used for ADC synthesis .

HY-128995AS

Glycyl-Exatecan-d5 hydrochloride
Glycyl-Exatecan-d₅ (Glycyl-DX-8951-d₅) hydrochloride is deuterium labeled Glycyl-Exatecan (HY-128995A). Glycyl-Exatecan (Glycyl-DX-8951), a derivative of Exatecan (HY-13631), is an anticancer agent. Glycyl-Exatecan has significantly antitumor activity. Glycyl-Exatecan can be used for cancers like solid tumors research.

HY-132316S

(rac)-2,4-O-Dimethylzearalenone-d6
(rac)-2,4-O-Dimethylzearalenone-d₆ is deuterium labeled (rac)-2,4-O-Dimethylzearalenone. (rac)-2,4-O-Dimethylzearalenone is a Zearalenone analog with blocked resorcinol OH groups

HY-112582S

N1-Methylpseudouridine-d3
N1-Methylpseudouridine-d3 is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-112581S

5-Methoxyuridine-d3
5-Methoxyuridine-d₃ is the deuterium labeled 5-Methoxyuridine (HY-112581). 5-Methoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-B0111S

Drospirenone-d4
Drospirenone-d₄ is the deuterium labeled Drospirenone. Drospirenone (Dihydrospirorenone) is a synthetic progestin that is an analog to spironolactone .

HY-B0111RS

Drospirenone-13C3
Drospirenone- ¹³C₃ is ¹³C labeled Drospirenone. Drospirenone (Dihydrospirorenone) is a synthetic progesterone that is an analog of Spironolactone .

HY-N8525S

3'-O-Acetylthymidine-13C
3'-O-Acetylthymidine- ¹³C is the ¹³C-labeled 3'-O-Acetylthymidine (HY-N8525). 3'-O-Acetylthymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-131100S

Homo Sildenafil-d5
Homo Sildenafil-d₅ is the deuterium labeled Homo Sildenafil. Homo Sildenafil, an analog of Sildenafil, acts as a phosphodiesterase inhibitor .

HY-15285

Doxercalciferol-d3
Doxercalciferol-d₃3 is the deuterated form of Doxercalciferol, which is a Vitamin D2 analog that acts as a vitamin D receptor activator (VDRA).

HY-17423S

Abacavir-d4
Abacavir-d₄ is the deuterium labeled Abacavir. Abacavir is a potent nucleoside analog reverse-transcriptase inhibitor (NRTI)[1][2].

HY-B0191S1

Bimatoprost-d4
Bimatoprost-d₄ is the deuterium labeled Bimatoprost. Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension.

HY-15329

Maxacalcitol-d6
Maxacalcitol-d₆6 is the deuterated form of Maxacalcitol (22-Oxacalcitriol), which is a non-calcemic vitamin D3 analog and VDR ligand of VDR-like receptors.

HY-B0017S

Telbivudine-d4
Telbivudine-d₄ is deuterium labeled Telbivudine. Telbivudine (Epavudine), an orally active thymidine nucleoside analog, is a potent antiviral inhibitor of hepatitis B virus (HBV) replication .

HY-W759404

Clascoterone-d5
Clascoterone-d5 (Cortexolone 17 alpha-propionate-d5) is the deuterated analog of Clascoterone. Clascoterone is a topical and peripheral androgen antagonist .

HY-W012732S

Isoquinoline-d7
Isoquinoline-d₇ is the deuterium labeled Isoquinoline . Isoquinoline is an analog of pyridine. Isoquinoline structural-based alkaloids, such as tropoloisoquinoline, phthalideisoquinoline, and naphthylisoquinoline has anti-cancer activities .

HY-W767399

8-Bromo-2'-deoxyguanosine-13C,15N2
8-Bromo-2'-deoxyguanosine- ¹³C, ¹⁵N₂ is the ¹³C- and ¹⁵N-labeled 8-Bromo-2'-deoxyguanosine (HY-W011168). 8-Bromo-2'-deoxyguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-A0057S

Gabapentin-d4
Gabapentin-d₄ is the deuterium labeled Gabapentin. Gabapentin (Neurontin) is a pharmaceutical agent, specifically a GABA analog. It was originally developed to treat epilepsy, and currently is also used to relieve neuropathic pain.

HY-W008048S

2',3'-O-Isopropylideneadenosine-13C5

2',3'-O-Isopropylideneadenosine- ¹³C₅ is the ¹³C-labeled 2',3'-O-Isopropylideneadenosine (HY-W008048). 2',3'-O-Isopropylideneadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) .

HY-152303S

N6-(4-Methoxybenzyl)adenosine-d3

N6-(4-Methoxybenzyl)adenosine-d₃ is deuterium labeled N6-(4-Methoxybenzyl)adenosine. N6-(4-Methoxybenzyl)adenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) .

HY-101541S

Docosahexaenoic acid-d5 methyl ester
Docosahexaenoic acid-d₅ methyl ester is the deuterium labeled Docosahexaenoic Acid methyl ester. Docosahexaenoic Acid methyl ester is a methylated docosahexaenoic acid analog which can be intercalated into membrane phospholipids without being oxidized or hydrolyzed .

HY-B0191S

Bimatoprost-d5
Bimatoprost-d₅ is a deuterium labeled Bimatoprost. Bimatoprost is a prostaglandin analog and is a topical hypotensive agent frequently used for treating ocular hypertension and glaucoma. Bimatoprost also has an antiadipogenic effect .

HY-101411S

4-Acetamidobutanoic acid-d3
4-Acetamidobutanoic acid-d3 is the deuterated analog of 4-Acetamidobutanoic acid (HY-101411). 4-Acetamidobutanoic acid (N-acetyl GABA), the main metabolite of GABA, exhibits antioxidant and antibacterial activities .

HY-W104379S

Arprinocid-15N3
Arprinocid-15N3 is ¹⁵N₃-labeled Arprinocid (HY-W104379). Arprinocid is a purine analog with activity against murine Toxoplasma gondii .

HY-W705873

Edoxudine-d5
Edoxudine-d₅ (EUDR-d₅) is the deuterium labeled Edoxudine (HY-B1011). Edoxudine is an antiviral active molecule and thymidine analog. Edoxudine is effective against herpes simplex virus .

HY-W739775

2,3’-Anhydrothymidine-d3

2,3’-Anhydrothymidine-d₃ (2’-Deoxy-3’,2-anhydro-5-methyluridine-d₃) is the deuterium labeled 2,3’-Anhydrothymidine (HY-154340). 2,3’-Anhydrothymidine; 2’-Deoxy-3’,2-anhydro-5-methyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-32348S1

Doxercalciferol-d6
Doxercalciferol-d₆ (1.alpha.-Hydroxyvitamin D2-d₆) is deuterium labeled Doxercalciferol. Doxercalciferol is a Vitamin D2 analog, acts as an activator of Vitamin D receptor, and prevent renal disease.

HY-B0937S

Amprolium-d7 bromide hydrobromide
Amprolium-d7 (bromide hydrobromide) is a deuterium-labeled of Amprolium (HY-B0937). Amprolium-d7 (bromide hydrobromide) is a coccidiostat used in poultry, is a thiamine analog, and blocks the thiamine transporter of Eimeria species .

HY-132277S

15-Keto Bimatoprost-d5
15-Keto Bimatoprost-d₅ is the deuterium labeled 15-Keto Bimatoprost. 15-Keto Bimatoprost is a prostaglandin F2α (PGF2α) analog that can be used for the research of ocular hypotensive .

HY-B0003S

Gemcitabine-13C,15N2 hydrochloride
Gemcitabine- ¹³C, ¹⁵N₂ (hydrochloride) is the ¹³C and ¹⁵N labeled Gemcitabine hydrochloride . Gemcitabine Hydrochloride (LY 188011 Hydrochloride) is a pyrimidine nucleoside analog antimetabolite and an antineoplastic agent. Gemcitabine Hydrochloride inhibits DNA synthesis and repair, resulting in autophagyand apoptosis .

HY-125407S

Palmitoyl serinol-d5
Palmitoyl serinol-d₅ is the deuterium labeled Palmitoyl serinol . Palmitoyl serinol (N-Palmitoyl serinol) is an analog of the endocannabinoid N-palmitoyl ethanolamine (PEA). Palmitoyl serinol improves the epidermal permeability barrier in both normal and inflamed skin .

HY-13966S

2-Deoxy-D-glucose-d1
2-Deoxy-D-glucose-d is the deuterium labeled 2-Deoxy-D-glucose. 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase .

HY-13605S

Cytarabine-d2
Cytarabine-d₂ is the deuterium labeled Cytarabine. Cytarabine, a nucleoside analog, causes S phase cell cycle arrest and inhibits DNA polymerase. Cytarabine inhibits DNA synthesis with an IC₅₀ of 16 nM. Cytarabine has antiviral effects against HSV .

HY-U00449S

AGN 193109-d7
AGN 193109-d₇ is the deuterium labeled AGN 193109. AGN 193109 is a retinoid analog, and acts as a specific and highly effective antagonist of retinoic acid receptors (RARs), with Kds of 2 nM, 2 nM, and 3 nM for RARα, RARβ, and RARγ, respectively.

HY-17536S

Selinexor-d5
Selinexor-d₅ (KPT-330-d₅) isthe deuterium labeled Selinexor (HY-17536). Selinexor (KPT-330), an analog of KPT-185, is an orally active and selective CRM1 inhibitor .

HY-13966S2

2-Deoxy-D-glucose-13C
2-Deoxy-D-glucose- ¹³C is the ¹³C labeled 2-Deoxy-D-glucose. 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase .

HY-118139S

Celecoxib-d4
Celecoxib-d₄ is the deuterium labeled Desmethyl Celecoxib. Desmethyl Celecoxib (compound 3b) is a selective cyclooxygenase-2 (COX-2) inhibitor (IC₅₀=32 nM) with anti-inflammatory activities. Desmethyl Celecoxib is an?analog?of Celecoxib and with the optimal yield of 75% .

HY-N7501S

Isoformononetin-d3
Isoformononetin-d3 is the deuterium labeled Isoformononetin (HY-N7501). Isoformononetin is an analog of Daidzein (HY-N0019) and has immunoprotective effects. Isoformononetin inhibits the differentiation of Th17 and B-cells lymphopoesis to promote osteogenesis in estrogen-deficient bone loss conditions .

HY-13966S4

2-Deoxy-D-glucose-13C-1
2-Deoxy-D-glucose- ¹³C-1 is the ¹³C labeled 2-Deoxy-D-glucose. 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase .

HY-10234S

Saracatinib-d3
Saracatinib-d3 (AZD0530-d3) (ZG5129) is the deuterium-labeled analog of Saracatinib (HY-10234). Saracatinib-d3 is an inhibitor of the Src kinase, which can inhibit severe sepsis caused by bacterial or various microbial infections .

HY-B1449S12

Uridine-d12
Uridine-d12 (β-Uridine-d12) is the deuterium labeled Uridine (HY-B1449). Uridine is a glycosylated pyrimidine-analog containing uracil attached to a ribose ring (or more specifically, aribofuranose) via a β-N1-glycosidic bond .

HY-W653975

Bisphenol B-d8
Bisphenol B-d₈ is the deuterium labeled Bisphenol B (HY-W013935). Bisphenol B is a very close structural analog of Bisphenol A (HY-18260), an endocrine disrupting chemical (EDC). Bisphenol B shows endocrine disruptive properties or other adverse effects on animal models .

HY-13017S

Ivacaftor-d9
Ivacaftor-d₉ is a potent CFTR modulator and exhibits an EC₅₀ value of 255 nM for CFTR potentiation in G551D/F508del HBE Cells. Ivacaftor-D9 acts as an orally active and improved deuterated Ivacaftor analog for cystic fibrosis research .

HY-W006371S

(2-Aminoethyl)phosphonic acid-d4
(2-Aminoethyl)phosphonic acid-d₄ is the deuterium labeled (2-Aminoethyl)phosphonic acid (HY-W006371). (2-Aminoethyl)phosphonic acid is an endogenous metabolite and amino acid analog. (2-Aminoethyl)phosphonic acid can be used for the synthesis of biological macromolecules and the preparation of hydrogels .

HY-13017S1

Ivacaftor-d19
Ivacaftor-d₉ is a potent CFTR modulator and exhibits an EC₅₀ value of 255 nM for CFTR potentiation in G551D/F508del HBE Cells. Ivacaftor-D9 acts as an orally active and improved deuterated Ivacaftor analog for cystic fibrosis research .

HY-101055S

Kinetin riboside-d5
Kinetin riboside-d₅ (N6-Furfuryladenosine-d₅) is the deuterium labeled Kinetin riboside (HY-101055). Kinetin riboside, a cytokinin analog, can induce apoptosis in cancer cells. It inhibits the proliferation of HCT-15 cells with an IC₅₀ of 2.5 μM .

HY-B0149S2

Tranexamic acid-13C6
Tranexamic acid- ¹³C₆ (Cyclocapron- ¹³C₆) is ¹³C labeled Tranexamic acid. Tranexamic acid (cyclocapron), a cyclic analog of lysine, is an orally active antifibrinolytic agent. Tranexamic acid attenuates the effects of severe trauma, inhibits urokinase plasminogen activator and ameliorates dry wrinkles. Tranexamic acid can used for the research of hemostasis .

HY-A0057AS2

Gabapentin-d4 hydrochloride
Gabapentin-d4 hydrochloride is the deuterium labeled Gabapentin hydrochloride (HY-A0057A). Gabapentin hydrochloride is a potent, orally active P/Q type Ca ²⁺ channel blocker. Gabapentin hydrochloride inhibits neuronal Ca ²⁺ influx and reduction of neurotransmitter release. Gabapentin hydrochloride is a GABA analog that can be used to relieve neuropathic pain .

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