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tert-Butyl 4-methylpiperazine-1-carboxylate-d<sub>8</sub>

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Oligonucleotides:	Rat Pre-designed siRNA Sets (1) Cationic Lipids (1) Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (1) siRNAs (3)

4707

Inhibitors & Agonists

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4364

Isotope-Labeled Compounds

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Oligonucleotides

Targets Recommended: P-glycoprotein

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-76548

tert-Butyl p-Toluate tert-Butyl p-methylbenzoate	Drug Intermediate	Others
tert-Butyl p-Toluate (tert-Butyl p-methylbenzoate) is a synthetic intermediate useful for pharmaceutical synthesis.

HY-W014540

*L-Proline tert-butyl* ester hydrochloride** tert-Butyl L-prolinate hydrochloride	Biochemical Assay Reagents
L-Proline tert-butyl ester hydrochloride (tert-Butyl L-prolinate hydrochloride) is a biologically active compound that has the activity of inhibiting cysteine and cathepsins, and is therefore widely used in the research and development of protease inhibitors. The characteristics of L-Proline tert-butyl ester hydrochloride make it of great significance in the field of biochemistry.

HY-21999

tert-Butyl 6-aminocaproate tert-Butyl 6-aminohexanoate	PROTAC Linkers	Cancer
tert-Butyl 6-aminocaproate (Tert-butyl 6-aminohexanoate) is a PROTAC linker. tert-Butyl 6-aminocaproate can be used in synthesis PROTAC CARM1/IKZF3 degrader-1 (HY-172368) .

HY-22391

tert-Butyl (7-aminoheptyl)carbamate tert-Butyl 2,8-diaminooctanoate	PROTAC Linkers	Cancer
tert-Butyl (7-aminoheptyl)carbamate (tert-Butyl 2,8-diaminooctanoate) is a PROTAC linker. tert-Butyl (7-aminoheptyl)carbamate can be used to synthesis CPD-10 (HY-168660) .

HY-W074953

tert-Butyl hydrogen tetradecanedioate	Biochemical Assay Reagents	Others
tert-Butyl Hydrogen Tetradecanedioate is a short linker featuring a carboxylic acid and a tert-butyl ester. Carboxylic acids can be reacted with alcohols or amines, while the tert-butyl ester can be selectively deprotected to allow for reactivity as a carboxylic acid to form esters or amides.

HY-Y0373

tert-Butyl carbazate	Biochemical Assay Reagents	Others
tert-Butyl hydrazinoformate is a biological molecule.

HY-W007722A

tert-Butyl alaninate hydrochloride	Amino Acid Derivatives	Others
tert-Butyl alaninate hydrochloride is an alanine derivative .

HY-42904

*Potassium tert-butyl* malonate**	Drug Intermediate	Cancer
Potassium tert-butyl malonate is an intermediate in the synthesis of malonate monoester potassium salt .

HY-Y1030

tert-Butyl L-valinate hydrochloride tert-Butyl (S)-2-amino-3-methylbutanoate hydrochloride	Amino Acid Derivatives	Others
tert-Butyl L-valinate hydrochloride is a valine derivative .

HY-W700253

tert-Butyl 4-methylpiperazine-1-carboxylate-d8	Isotope-Labeled Compounds	Others
tert-Butyl 4-methylpiperazine-1-carboxylate-d₈ is the deuterium labeled tert-Butyl 4-methylpiperazine-1-carboxylate (HY-W050208).

HY-170057

*Pseudoephedrine tert-butyl* carbamate**	Drug Derivative	Neurological Disease
Pseudoephedrine tert-butyl carbamate is an amphetamine.

HY-W248248

tert-Butyl 9-aminononanoate	PROTAC Linkers	Cancer
tert-Butyl 9-aminononanoate is a PROTAC linker. tert-Butyl 9-aminononanoate can be used in synthesis PROTAC sEH-degrader-1 (HY-159494) .

HY-W053801

tert-Butyl benzylglycinate	Amino Acid Derivatives	Others
tert-Butyl benzylglycinate is a Glycine (HY-Y0966) derivative .

HY-75331

*Glycine tert-butyl* ester hydrochloride**	Amino Acid Derivatives	Others
Glycine tert-butyl ester hydrochloride is a Glycine (HY-Y0966) derivative .

HY-43191

tert-Butyl 6-bromohexanoate	PROTAC Linkers	Cancer
tert-Butyl 6-bromohexanoate is a PROTAC linker. tert-Butyl 6-bromohexanoate can be used to design PROTAC, such as PROTAC ERK5 degrader-1 (HY-176528) .

HY-W013686

tert-Butyl D-leucinate hydrochloride	Amino Acid Derivatives	Others
tert-Butyl D-leucinate hydrochloride is a leucine derivative .

HY-135380R

*Atorvastatin acetonide tert-butyl* ester (Standard)**	Drug Intermediate Reference Standards	Cardiovascular Disease
Atorvastatin acetonide tert-butyl ester (Standard) is the analytical standard of Atorvastatin acetonide tert-butyl ester. This product is intended for research and analytical applications. Atorvastatin acetonide tert-butyl ester is a useful pharmaceutical intermediate in the preparation of Atorvastatin salts. Atorvastatin is an orally active HMG-CoA reductase inhibitor and has the ability to effectively decrease blood lipids .

HY-Z0809R

tert-Butyl (2-hydroxypropyl)carbamate (Standard)	Reference Standards
tert-Butyl (2-hydroxypropyl)carbamate (Standard) is the analytical standard of tert-Butyl (2-hydroxypropyl)carbamate. This product is intended for research and analytical applications.

HY-32865

tert-Butyl 2,2,2-trichloroacetimidate	Bacterial Drug Intermediate	Infection
tert-Butyl 2,2,2-trichloroacetimidate is a tert-butylation reagent. tert-Butyl 2,2,2-trichloroacetimidate achieves mild, nonreversible tert-butylation of alcohols and phenols. tert-Butyl 2,2,2-trichloroacetimidate is used in the synthesis of antimicrobial agents .

HY-W722986

tert-Butyl ethyl(isopropyl)carbamate-d5	Isotope-Labeled Compounds	Others
tert-Butyl ethyl(isopropyl)carbamate-d₅ is the deuterium labeled tert-Butyl ethyl(isopropyl)carbamate.

HY-W042009A

*(R)-Phenylglycine tert-butyl* ester hydrochloride**	Amino Acid Derivatives	Others
(R)-Phenylglycine tert-butyl ester hydrochloride is a Glycine (HY-Y0966) derivative .

HY-W002322

tert-Butyl Diethylphosphonoacetate	Biochemical Assay Reagents	Others
tert-Butyl 2-(diethoxyphosphoryl)acetate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W007408

tert-Butyl 2-aminoacetate	Amino Acid Derivatives	Others
tert-Butyl 2-aminoacetate is a Glycine (HY-Y0966) derivative .

HY-W013638

tert-Butyl 2-(methylamino)acetate	Amino Acid Derivatives	Others
tert-Butyl 2-(methylamino)acetate is a Glycine (HY-Y0966) derivative .

HY-76929S

tert-Butyl 4-aminobenzoate-13C6	Isotope-Labeled Compounds	Others
tert-Butyl 4-aminobenzoate- ¹³C₆ is the ¹³C labeled tert-Butyl 4-aminobenzoate .

HY-Z0809

tert-Butyl (2-hydroxypropyl)carbamate	Drug Intermediate	Others
tert-Butyl (2-hydroxypropyl)carbamate is a drug impurity.

HY-W019095

tert-Butyl 4-hydroxybutanoate	Biochemical Assay Reagents	Others
tert-Butyl 4-hydroxybutanoate is a short aliphatic linker featuring a primary alcohol and a t-butyl ester.

HY-12692

*DO3A tert-Butyl* ester** DO3A tert-Butyl; DO3A-t-Bu-ester	Drug Derivative	Cancer
DOTA tert-Butyl ester is a cyclic tosamide benzyl derivative.

HY-34519

*(S)-2-Amino-3-(4-hydroxyphenyl)propionic acid tert-butyl* ester** L-Tyrosine tert-Butyl ester; tert-Butyl (S)-2-amino-3-(4-hydroxyphenyl)propanoate; tert-Butyl L-tyrosinate	Amino Acid Derivatives	Others
(S)-2-Amino-3-(4-hydroxyphenyl)propionic acid tert-butyl ester is a tyrosine derivative .

HY-W738480

*L-Phenylalanine tert-butyl* ester-d5** (R)-tert-Butyl 2-amino-3-phenylpropanoate-d<sub>5sub>	Isotope-Labeled Compounds	Others
L-Phenylalanine tert-butyl ester-d₅ ((R)-Tert-Butyl 2-amino-3-phenylpropanoate-d₅) is the deuterium labeled (S)-tert-Butyl 2-amino-3-phenylpropanoate (HY-W108426).

HY-172643

tert-Butyl 2-((5-bromopentyl)oxy)acetate	PROTAC Linkers	Cancer
tert-Butyl 2-((5-bromopentyl)oxy)acetate is a PROTAC linker. tert-Butyl 2-((5-bromopentyl)oxy)acetate can be used in synthesis ERD-308 (HY-128600) .

HY-W454945S

tert-Butyl piperazine-1-carboxylate-2,2,3,3,5,5,6,6-d8 N-Boc-piperazine-d<sub>8sub>	Isotope-Labeled Compounds	Others
tert-Butyl piperazine-1-carboxylate-2,2,3,3,5,5,6,6-d₈ is the deuterium labeled tert-Butyl piperazine-1-carboxylate .

HY-W740068

tert-Butyl 4-Nitrophenyl Carbonate-d9	Isotope-Labeled Compounds	Others
tert-Butyl 4-Nitrophenyl Carbonate-d₉ is the deuterium labeled Tert-Butyl (4-nitrophenyl) carbonate (HY-W683522).

HY-34346

tert-Butyl (2-hydrazinyl-2-oxoethyl)carbamate [[[Hydrazino]carbonyl]methyl]carbamic acid tert-Butyl ester; tert-Butyl (2-hydrazinyl-2-oxoethyl)carbamate; tert-Butyl (2-hydrazinyl-2-oxoethyl)carbamate	Amino Acid Derivatives	Others
tert-Butyl (2-hydrazinyl-2-oxoethyl)carbamate is a Glycine (HY-Y0966) derivative .

HY-139265

*3,4-Mdma tert-butyl* carbamate**	Drug Derivative	Neurological Disease
3,4-Mdma tert-butyl carbamate is an amphetamine.

HY-W011657

tert-Butyl 4-(bromomethyl)benzoate	Others	Others
tert-Butyl 4-(bromomethyl)benzoate is a synthetic intermediate useful for compound synthesis .

HY-44141

tert-Butyl 3-(2-iodoethoxy)propanoate	PROTAC Linkers	Cancer
tert-Butyl 3-(2-iodoethoxy)propanoate is a PROTAC linker, which refers to the PEG composition. tert-Butyl 3-(2-iodoethoxy)propanoate can be used in the synthesis of PROTAC FAK degrader 1 (HY-119932) .

HY-W091879

tert-Butyl 7-bromoheptanoate	PROTAC Linkers	Cancer
tert-Butyl 7-bromoheptanoate is a PROTAC linker can be used in the synthesis of PROTACs, such as MCB-36 (HY-176786) .

HY-132775S

*2-Benzyloxy atorvastatin-d5 acetonide tert-butyl* ester**	Isotope-Labeled Compounds	Others
2-Benzyloxy Atorvastatin-d₅ Acetonide tert-Butyl Ester is the deuterium labeled 2-Benzyloxy Atorvastatin Acetonide tert-Butyl Ester .

HY-130715

tert-Butyl 11-aminoundecanoate	PROTAC Linkers	Cancer
tert-Butyl 11-aminoundecanoate (compound 6b) is a PROTAC linker, which refers to the PEG composition. tert-Butyl 11-aminoundecanoate can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins .

HY-Y1778

*N-(Diphenylmethylene)glycine tert-butyl* ester**	Fluorescent Dye	Others
N-(Diphenylmethylene)glycine tert-butyl ester is a dye, also as the raw material and intermediate for organic syntheses .

HY-W003696

**tert-Butyl 5-bromoisoindoline-2-carboxylate** tert-Butyl 5-bromo-1,3-dihydro-2H-isoindole-2- carboxylate	PROTAC Linkers	Cancer
tert-Butyl 5-bromoisoindoline-2-carboxylate (Tert-butyl 5-bromo-1,3-dihydro-2H-isoindole-2- carboxylate) is a PROTAC Linker. tert-Butyl 5-bromoisoindoline-2-carboxylate can be used in synthesis PTOTAC HSD17B13 degrader 1 (HY-159651) .

HY-W009359S

tert-Butyl 4-benzylpiperazine-1-carboxylate-d8	Isotope-Labeled Compounds	Others
tert-Butyl 4-benzylpiperazine-1-carboxylate-d₈ is the deuterium labeled tert-Butyl 4-benzylpiperazine-1-carboxylate .

HY-Z0669R

tert-butyl (6-(4-hydroxyphenoxy)hexyl) carbonate (Standard)	Reference Standards
tert-butyl (6-(4-hydroxyphenoxy)hexyl) carbonate (Standard) is the analytical standard of tert-butyl (6-(4-hydroxyphenoxy)hexyl) carbonate. This product is intended for research and analytical applications.

HY-W325356

tert-Butyl 3,5-dinitrobenzoate	Fluorescent Dye	Cancer
Tert-butyl 3,5-dinitrobenzoate is an intermediate or reactant in organic synthesis and can also play a role in drug synthesis, dye preparation and other chemical fields.The nitro functional group of Tert-butyl 3,5-dinitrobenzoate has certain reactivity in organic chemistry and can participate in various reactions, such as electrophilic substitution, aromatic amine reaction, etc .

HY-135380

*Atorvastatin acetonide tert-butyl* ester**	Drug Intermediate	Cardiovascular Disease
Atorvastatin acetonide tert-butyl ester is a useful pharmaceutical intermediate in the preparation of Atorvastatin salts. Atorvastatin is an orally active HMG-CoA reductase inhibitor and has the ability to effectively decrease blood lipids .

HY-40172

tert-Butyl (3-aminopropyl)carbamate	Biochemical Assay Reagents	Others
tert-Butyl (3-aminopropyl)carbamate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-Z0669

tert-Butyl (6-(4-hydroxyphenoxy)hexyl) carbonate	Drug Intermediate	Others
tert-butyl (6-(4-hydroxyphenoxy)hexyl) carbonate is a drug impurity.

HY-W000830

tert-Butyl 2-((tert-butoxycarbonyl)amino)acetate	Amino Acid Derivatives	Others
tert-Butyl 2-((tert-butoxycarbonyl)amino)acetate is a Glycine (HY-Y0966) derivative .

HY-W457953

tert-Butyl N-(4-azidobutyl)carbamate	Biochemical Assay Reagents	Others
tert-Butyl N-(4-azidobutyl)carbamate is N-Boc protected crosslinker. tert-Butyl N-(4-azidobutyl)carbamate can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W010037

*2-(tert-Butyl)-4-methoxyphenol*	Monophenols Classification of Application Fields Source classification Phenols Endogenous metabolite Inflammation/Immunology Disease Research Fields	COX
2-tert-Butyl-4-methoxyphenol is a major component of Butylhydroxyanisole (BHA) (HY-B1066). 2-tert-Butyl-4-methoxyphenol is an antioxidant agent, that inhibits expression of Cox2 and Tnfa genes upon stimulation with Lipopolysaccharides (HY-D1056). 2-tert-Butyl-4-methoxyphenol exhibits anti-inflammatory activity, combined with 2,6-di-tert-butyl-4-methylphenol (BHT) .

HY-W024365

*3-tert-Butyl-4-methoxyphenol*	Monophenols Source classification Jatropha curcas Linn. Phenols Euphorbiaceae Plants	PROTAC Linkers
3-tert-Butyl-4-methoxyphenol is a PROTAC linker, belongs to alkyl/ether class, with insecticidal activity. 3-tert-Butyl-4-methoxyphenol also induced increased activities of glutathione (GSH) S-transferase and epoxide hydrolase in the liver and forestomach tissues of A/HeJ mice, regulating the carcinogen metabolism system .

HY-125833

Alpha-Naphthoflavone 5+ Cited Publications	Flavonoids Flavones Source classification Indigofera heterantha Wall. ex Brand. Plants Compositae Disease Research Fields Cancer	Cytochrome P450 Aryl Hydrocarbon Receptor Apoptosis
Alpha-Naphthoflavone is an orally active flavonoid that is a potent, competitive inhibitor of aromatase< b>aromatase. < b > IC < sub > 50 < / sub > < / b > and < b > K < sub > I < / sub > < / b > value were 0.5 and 0.2 microns. Alpha-Naphthoflavone can inhibit cell proliferation and induce apoptosis .

HY-N1506

Ganodermanontriol	Other Terpenoids Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Terpenoids Polyporaceae Source classification Ganoderma lucidum (Leyss. Ex Fr.) Karst. Plants Endogenous metabolite Disease Research Fields Cancer	Epigenetic Reader Domain p38 MAPK
Ganodermanontriol, a sterol isolated from Ganoderma lucidum, induces anti-inflammatory activity in tert-butyl hydroperoxide (t-BHP)-damaged hepatic cells through the expression of HO-1. Ganodermanontriol exhibits hepatoprotective activity .

HY-N2996

Ganodermanondiol	Infection Triterpenes Microorganisms Classification of Application Fields Terpenoids Polyporaceae Source classification Ganoderma lucidum (Leyss. Ex Fr.) Karst. Plants Disease Research Fields	HIV Protease
Ganodermanondiol is a melanogenesis inhibitor isolated from the Ganoderma lucidum .Ganodermanondiol exhibits potent cytoprotective effects on tert-butyl hydroperoxide-induced hepatotoxicity . Ganodermanondiol shows significant anti-HIV-1 protease activity with an IC₅₀ of 90 μM . Ganodermanondiol exhibits a strong anticomplement activity against the classical pathway of the complement system with an IC₅₀ of 41.7μM .

HY-W011474

Geranylgeraniol	Natural Products Microorganisms	NF-κB
Geranylgeraniol is an orally acitve vitamin K₂ sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model .

HY-W024365R

*3-tert-Butyl-4-methoxyphenol (Standard)*	Monophenols Source classification Jatropha curcas Linn. Phenols Euphorbiaceae Plants	PROTAC Linkers Reference Standards
3-tert-Butyl-4-methoxyphenol (Standard) is the analytical standard of 3-tert-Butyl-4-methoxyphenol. This product is intended for research and analytical applications. 3-tert-Butyl-4-methoxyphenol is a PROTAC linker, belongs to alkyl/ether class, with insecticidal activity. 3-tert-Butyl-4-methoxyphenol also induced increased activities of glutathione (GSH) S-transferase and epoxide hydrolase in the liver and forestomach tissues of A/HeJ mice, regulating the carcinogen metabolism system .

HY-W010549R

2-Methylcyclohexanone (Standard)	Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Reference Standards Endogenous Metabolite Biochemical Assay Reagents Fungal
3-tert-Butyl-4-methoxyphenol (Standard) is the analytical standard of 3-tert-Butyl-4-methoxyphenol. This product is intended for research and analytical applications. 3-tert-Butyl-4-methoxyphenol is a PROTAC linker, belongs to alkyl/ether class, with insecticidal activity. 3-tert-Butyl-4-methoxyphenol also induced increased activities of glutathione (GSH) S-transferase and epoxide hydrolase in the liver and forestomach tissues of A/HeJ mice, regulating the carcinogen metabolism system .

HY-125833R

Alpha-Naphthoflavone (Standard)	Flavonoids Flavones Source classification Indigofera heterantha Wall. ex Brand. Plants Compositae	Cytochrome P450 Aryl Hydrocarbon Receptor Apoptosis
Alpha-Naphthoflavone (Standard) is the analytical standard of Alpha-Naphthoflavone. This product is intended for research and analytical applications. Alpha-Naphthoflavone is an orally active flavonoid that is a potent, competitive inhibitor of aromatase< b>aromatase. < b > IC < sub > 50 < / sub > < / b > and < b > K < sub > I < / sub > < / b > value were 0.5 and 0.2 microns. Alpha-Naphthoflavone can inhibit cell proliferation and induce apoptosis .

HY-N11799

Neochilenin 3-O-Methylquercetin 4′-O-glucoside	Flavonoids Source classification Plants Compositae Other Flavonoids	Others
Neochilenin (3-O-Methylquercetin 4 '-O-glucoside) is a glycoside of 3-O-methylquercetin, which can be isolated from the sub-family Cereoideae (Cactaceae). .

HY-N15356

9-Oxooctadecanedioic acid	Ketones, Aldehydes, Acids Source classification Plants Quercus suber L. Fagaceae	Bacterial
9-Oxooctadecanedioic acid is an α,ω-dicarboxylic fatty acid monomer found in the cork suberin of Quercus suber. It contributes to the formation of the hydrophobic barrier structure in plant cell walls and may play an important role in functions such as water resistance and protection against microbial penetration .

HY-P2274

Argifin	Infection Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields	Parasite
Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms, with IC₅₀s of 0.025 μM, 6.4 μM , 1.1 μM and 4.5 μM for SmChiA (Serratia marcescens chitinaese A), SmChiB, Aspergillus fumigatus chitinase B1 and human chitotriosidase, respectively .

HY-W011474R

Geranylgeraniol (Standard)	Natural Products Microorganisms	Reference Standards NF-κB
Geranylgeraniol (Standard) is the analytical standard of Geranylgeraniol. This product is intended for research and analytical applications. Geranylgeraniol is an orally acitve vitamin K2 sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model [4].

HY-N10192

Aculene D	Infection Microorganisms Classification of Application Fields Terpenoids Sesquiterpenes Source classification Disease Research Fields	Endogenous Metabolite Bacterial
Aculene D, a fungal metabolite, shows quorum sensing (QS) inhibitory activity against Chromobacterium violaceum CV026, and could significantly reduce violacein production in N-hexanoyl-l-homoserine lactone (C6-HSL) induced C. violaceum CV026 cultures at sub-inhibitory concentrations .

HY-N0662

Amentoflavone Maximum Cited Publications 12 Publications Verification Didemethyl-ginkgetin	Flavonoids Classification of Application Fields Source classification Phenols Polyphenols Selaginellaceae Plants Biflavones Selaginella tamariscina (P. Beauv.) Spring Disease Research Fields Cancer	Reactive Oxygen Species (ROS) Apoptosis Bacterial Fungal RSV GABA Receptor
Amentoflavone (Didemethyl-ginkgetin) is a potent and orally active GABA(A) negative modulator. Amentoflavone also shows anti-inflammatory, antioxidative, anti-viral, anti-tumor, anti-radiation, anti-fungal, antibacterial activity. Amentoflavone induces apoptosis and cell cycle arrest at sub-G1 phase .

HY-W011370

Pelargonidin chloride 1 Publications Verification	Anthocyans Flavonoids Classification of Application Fields Leguminosae Source classification Other Diseases Phenols Polyphenols Plants Phaseolus vulgaris Linn. Disease Research Fields	Quinone Reductase Reactive Oxygen Species (ROS)
Pelargonidin chloride is an anthocyanidin and also is a scavenger of nitric oxide radical and has antioxidant activities. Pelargonidin inhibits cell viability and induces cell cycle arrest at sub-G1 phase. Pelargonidin chloride increases the mRNA and protein expression of HO-1, NQO1, Nrf2. Pelargonidin chloride improves Aβ-induced memory and learning impairment .

HY-P2274R

Argifin (Standard)	Natural Products Microorganisms Source classification	Reference Standards Parasite
Argifin (Standard) is the analytical standard of Argifin. This product is intended for research and analytical applications. Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms, with IC50s of 0.025 μM, 6.4 μM , 1.1 μM and 4.5 μM for SmChiA (Serratia marcescens chitinaese A), SmChiB, Aspergillus fumigatus chitinase B1 and human chitotriosidase, respectively[1].

HY-N0662R

Amentoflavone (Standard) Didemethyl-ginkgetin (Standard)	Flavonoids Source classification Phenols Polyphenols Selaginellaceae Plants Biflavones Selaginella tamariscina (P. Beauv.) Spring	Reference Standards Reactive Oxygen Species (ROS) Apoptosis Bacterial Fungal RSV GABA Receptor
Amentoflavone (Standard) is the analytical standard of Amentoflavone. This product is intended for research and analytical applications. Amentoflavone (Didemethyl-ginkgetin) is a potent and orally active GABA(A) negative modulator. Amentoflavone also shows anti-inflammatory, antioxidative, anti-viral, anti-tumor, anti-radiation, anti-fungal, antibacterial activity. Amentoflavone induces apoptosis and cell cycle arrest at sub-G1 phase .

HY-N4145

Procyanidin A3 Cinnamtannin A3; Cinnamtannin II	Structural Classification Cinnamomum cassia (L.) D. Don Source classification Phenols Polyphenols Plants Lauraceae	Drug Derivative Bacterial Fungal
Procyanidin A3 (Cinnamtannin A3; Cinnamtannin II) is a sub class of Proanthocyanidins (HY-N0794). Proanthocyanidin are a class of polyphenolic that are widely distributed in higher plants, consisted of an electrophilic flavanyl unit. Proanthocyanidin can be used as antioxidant and anti-cancer agent. Proanthocyanidin also exhibit anti-inflammatory, cardioprotective, antibacterial and antifungal properties, which can be used in the treatment of chronic venous insufficiency, capillary fragility, sunburn and retinopathy .

HY-B0504S

Creatinine-d3 5 Publications Verification NSC13123-d<sub>3sub>	Classification of Application Fields Metabolic Disease Disease Research Fields	Isotope-Labeled Compounds Endogenous Metabolite
Creatinine-d₃ is a deuterium labeled Creatinine. Creatinine is a break-down product of creatine phosphate in muscle .

HY-A0248A

Polymyxin B1 1 Publications Verification	Infection Microorganisms Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Disease Research Fields Other Antibiotics	Bacterial
Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment .

Cat. No.	Product Name	Chemical Structure

HY-W454945S

tert-Butyl piperazine-1-carboxylate-2,2,3,3,5,5,6,6-d8
tert-Butyl piperazine-1-carboxylate-2,2,3,3,5,5,6,6-d₈ is the deuterium labeled tert-Butyl piperazine-1-carboxylate .

HY-W700253

tert-Butyl 4-methylpiperazine-1-carboxylate-d8
tert-Butyl 4-methylpiperazine-1-carboxylate-d₈ is the deuterium labeled tert-Butyl 4-methylpiperazine-1-carboxylate (HY-W050208).

HY-W722986

tert-Butyl ethyl(isopropyl)carbamate-d5
tert-Butyl ethyl(isopropyl)carbamate-d₅ is the deuterium labeled tert-Butyl ethyl(isopropyl)carbamate.

HY-76929S

tert-Butyl 4-aminobenzoate-13C6
tert-Butyl 4-aminobenzoate- ¹³C₆ is the ¹³C labeled tert-Butyl 4-aminobenzoate .

HY-W738480

*L-Phenylalanine tert-butyl* ester-d5**
L-Phenylalanine tert-butyl ester-d₅ ((R)-Tert-Butyl 2-amino-3-phenylpropanoate-d₅) is the deuterium labeled (S)-tert-Butyl 2-amino-3-phenylpropanoate (HY-W108426).

HY-W740068

tert-Butyl 4-Nitrophenyl Carbonate-d9
tert-Butyl 4-Nitrophenyl Carbonate-d₉ is the deuterium labeled Tert-Butyl (4-nitrophenyl) carbonate (HY-W683522).

HY-132775S

*2-Benzyloxy atorvastatin-d5 acetonide tert-butyl* ester**
2-Benzyloxy Atorvastatin-d₅ Acetonide tert-Butyl Ester is the deuterium labeled 2-Benzyloxy Atorvastatin Acetonide tert-Butyl Ester .

HY-W009359S

tert-Butyl 4-benzylpiperazine-1-carboxylate-d8
tert-Butyl 4-benzylpiperazine-1-carboxylate-d₈ is the deuterium labeled tert-Butyl 4-benzylpiperazine-1-carboxylate .

HY-W016730S

tert-Butyl (1-hydroxypropan-2-yl)carbamate-d6
tert-Butyl (1-hydroxypropan-2-yl)carbamate-d₆ is the deuterium labeled tert-Butyl (1-hydroxypropan-2-yl)carbamate .

HY-W705198

Tert-butyl [1,4'-bipiperidine]-1'-carboxylate-d10
Tert-butyl [1,4'-bipiperidine]-1'-carboxylate-d₁₀ is the deuterium labeled Tert-butyl [1,4'-bipiperidine]-1'-carboxylate (HY-W293345).

HY-W704049

**tert-Butyl 4-(methyl-d3)piperazine-1-carboxylate**
tert-Butyl 4-(methyl-d₃)piperazine-1-carboxylate is the deuterium labeled tert-Butyl 4-methylpiperazine-1-carboxylate (HY-W050208).

HY-21376S

tert-Butyl 4-amino-1H-pyrazole-1-carboxylate-d2
tert-Butyl 4-amino-1H-pyrazole-1-carboxylate-d₂ is the deuterium labeled tert-Butyl 4-amino-1H-pyrazole-1-carboxylate.

HY-32208S

tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate-d4
tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate-d₄ is the deuterium labeled tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate[1].

HY-W454729S

tert-Butyl 4-hydroxypiperidine-1-carboxylate-3,3,4,5,5-d5
tert-Butyl 4-hydroxypiperidine-1-carboxylate-3,3,4,5,5-d₅ is the deuterium labeled tert-Butyl 4-hydroxypiperidine-1-carboxylate .

HY-W747123

*4-Acetyl-6-tert-butyl-1,1-dimethylindan-d6*
4-Acetyl-6-tert-butyl-1,1-dimethylindan-d₆ (Celestolide-d₆) is the deuterium labeled 4-Acetyl-6-tert-butyl-1,1-dimethylindan (HY-W102485).

HY-132350S

*iso-Nadolol (tert-Butyl-d9)*
iso-Nadolol (tert-Butyl-d₉) is the deuterium labeled iso-Nadolol (tert-Butyl) .

HY-W010037S

*2-(tert-Butyl)-4-methoxyphenol-d3*
2-(tert-Butyl)-4-methoxyphenol-d₃ is deuterium labeled 2-(tert-Butyl)-4-methoxyphenol.

HY-W024365S

*2-tert-Butyl-4-hydroxyanisole-d3*
2-tert-Butyl-4-hydroxyanisole-d₃ is deuterium labeled 3-tert-Butyl-4-methoxyphenol.

HY-W745885

*2-(5-tert-Butyl-2-hydroxyphenyl)benzotriazole-d9*
2-(5-tert-Butyl-2-hydroxyphenyl)benzotriazole-d₉ (2-(2H-Benzo[d][1,2,3]triazol-2-yl)-4-(tert-butyl)phenol-d₉) is the deuterium labeled 2-(2H-Benzo[d][1,2,3]triazol-2-yl)-4-(tert-butyl)phenol (HY-W440436).

HY-W010216S

*4-(tert-Butyl)cyclohexanone-d9*
4-(tert-Butyl)cyclohexanone-d₉ is the deuterium labeled 4-(tert-Butyl)cyclohexanone .

HY-Y1169S2

Fmoc-Asp(OtBu)-OH-d3
Fmoc-Asp(OtBu)-OH-d₃ (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate-d₃) is deuterium labeled Fmoc-Asp(OtBu)-OH. Fmoc-Asp(OtBu)-OH (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate) is a aspartate derivative containing amine protecting group Fmoc. Fmoc-Asp(OtBu)-OH can be used for peptide synthesis .

HY-W585914S

*2-(3-Sec-butyl-5-tert-butyl-2-hydroxyphenyl)benzotriazole-d4*
2-(3-Sec-butyl-5-tert-butyl-2-hydroxyphenyl)benzotriazole-d₄ is deuterium labeled 2-(3-Sec-butyl-5-tert-butyl-2-hydroxyphenyl)benzotriazole .

HY-W719247

*Di-tert-butyl* Butylphosphonate-d7**
Di-tert-butyl Butylphosphonate-d₇ is the deuterium labeled Di-tert-butyl Butylphosphonate.

HY-W017456S

*4-(tert-Butyl)aniline-d15*
4-(tert-Butyl)aniline-d₁₅ is the deuterium labeled 4-(tert-Butyl)aniline .

HY-W749302

*O-tert-Butyl-dimethylsilyl curcumin-d6*
O-tert-Butyl-dimethylsilyl curcumin-d₆ is the deuterium labeled O-tert-Butyl-dimethylsilyl curcumin.

HY-128463S

N-tert-Butyl-α-phenylnitrone-d14

N-tert-Butyl-α-phenylnitrone-d₁₄ is the deuterium labeled N-tert-Butyl-α-phenylnitrone . N-tert-Butyl-α-phenylnitrone is a nitrone-based free radical scavenger that forms nitroxide spin adducts. N-tert-Butyl-α-phenylnitrone inhibits COX2 catalytic activity. N-tert-Butyl-α-phenylnitrone has potent ROS scavenging, anti-inflammatory, neuroprotective, anti-aging and anti-diabetic activities, and can penetrate the blood-brain barrier .

HY-W707595

*O-tert-Butyl-2-hydroxy efavirenz-d5*
O-tert-Butyl-2-hydroxy efavirenz-d₅ is the deuterium labeled O-tert-Butyl-2-hydroxy Efavirenz (HY-W744274).

HY-W102278S

Tinuvin-327-d3
Tinuvin-327-d₃ (2,4-Di-tert-Butyl-6-(5-chloro-2H-benzotriazol-2-yl)phenol-d₃ (UV-327-d₃)) is deuterium labeled 2,4-Di-tert-butyl-6-(5-chloro-2H-benzo[d][1,2,3]triazol-2-yl)phenol .

HY-W087240S

*1,3-Di-tert-butyl-5-iodobenzene-d3*
1,3-Di-tert-butyl-5-iodobenzene-d₃ is a deuterium labeled 1,3-Di-tert-butyl-5-iodobenzene.

HY-W017145S

*4-(tert-Butyl)benzene-1,2-diol-d12*
4-(tert-Butyl)benzene-1,2-diol-d₁₂ is the deuterium labeled 4-(tert-Butyl)benzene-1,2-diol .

HY-W701625

*N,N'-Diacetyl-L-cystine bis(tert-butyl) diester-d6*
N,N'-Diacetyl-L-cystine bis(tert-butyl) diester-d₆ is the deuterium labeled N,N'-Diacetyl-L-cystine bis(tert-butyl) diester.

HY-W011565S1

*3,6-Di-tert-butyl-9H-carbazole-d25*
3,6-Di-tert-butyl-9H-carbazole-d₂₅ is a deuterium labeled 3,6-Di-tert-butyl-9H-carbazole.

HY-W011565S

*3,6-Di-tert-butyl-9H-carbazole-d6*
3,6-Di-tert-butyl-9H-carbazole-d₆ is the deuterium labeled 3,6-Di-tert-butyl-9H-carbazole.

HY-W713989

Methyl 2-(4-(tert-butyl)benzyl)propanoate-3,3,3-d3
Methyl 2-(4-(tert-butyl)benzyl)propanoate-3,3,3-d₃ is the deuterium labeled Methyl 2-(4-(tert-butyl)benzyl)propanoate.

HY-W283336S

*2,5-Di-(tert-butyl)-4-methoxyphenol-3,6-d20*
2,5-Di-(tert-butyl)-4-methoxyphenol-3,6-d₂₀ is the deuterium labeled 2,5-Di-tert-butyl-4-methoxyphenol .

HY-W077436S

*2,6-Di-(tert-butyl)-4-methoxyphenol-3,5-d20*
2,6-Di-(tert-butyl)-4-methoxyphenol-3,5-d₂₀ is the deuterium labeled 2,6-Di-tert-butyl-4-methoxyphenol .

HY-Y1166S

*N-(9-Fluorenylmethoxycarbonyl)glutamic acid α-tert-butyl* ester-13C5,15N**
N-(9-Fluorenylmethoxycarbonyl)glutamic acid α-tert-butyl ester- ¹³C₅, ¹⁵N is the ¹³C-labeled and ¹⁵N-labeled N-(9-Fluorenylmethoxycarbonyl)glutamic acid α-tert-butyl ester (HY-Y1166). N-(9-Fluorenylmethoxycarbonyl)glutamic acid α-tert-butyl ester is a glutamic acid derivative .

HY-10844S1

Pretomanid-d5
Pretomanid-d₅ is deuterated labeled Pretomanid (HY-10844). Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 μg/mL.

HY-W440436S

*2-(2H-Benzo[d][1,2,3]triazol-2-yl)-4-(tert-butyl)phenol-d4*
2-(2H-Benzo[d][1,2,3]triazol-2-yl)-4-(tert-butyl)phenol-d₄ is deuterium labeled 2-(2H-Benzo[d][1,2,3]triazol-2-yl)-4-(tert-butyl)phenol .

HY-W717038

*Di-(tert-butyl-dimethylsilyl) curcumin-d6*
Di-(tert-butyl-dimethylsilyl) curcumin-d₆ is the deuterium labeled (1E,4Z,6E)-1,7-Bis(4-((tert-butyldimethylsilyl)oxy)-3-methoxyphenyl)-5-hydroxyhepta-1,4,6-trien-3-one (HY-W703940).

HY-W011886S

*N2-(tert-Butyl)-N4-cyclopropyl-6-(methylthio)-1,3,5-triazine-2,4-diamine-d9*
N2-(tert-Butyl)-N4-cyclopropyl-6-(methylthio)-1,3,5-triazine-2,4-diamine-d₉ is the deuterium labeled N2-(tert-Butyl)-N4-cyclopropyl-6-(methylthio)-1,3,5-triazine-2,4-diamine .

HY-W778065

*N-(tert-Butoxycarbonyl)aniline-13C6*
N-(tert-Butoxycarbonyl)aniline- ¹³C₆ is the ¹³C-labeled tert-Butyl phenylcarbamate (HY-W009968).

HY-B0615AS

Moricizine-d8(Hydrochloride)
Moricizine-d₈ Hydrochloride is the deuterium labeled Moricizine Hydrochloride (HY-B0615A). Moricizine Hydrochloride is an orally active Class I antiarrhythmic agent. Moricizine Hydrochloride decreases the maximum rate of phase 0 depolarization; increases rates of phase 2 and 3 repolarization, decreases action potential duration, and decreases effective refractory period .

HY-17037S1

Pirenzepine-d8 dihydrochloride

Pirenzepine-d₈ (LS 519-d₈; Pirenzepin-d₈) dihydrochloride is a deuterium labeled Pirenzepine (dihydrochloride) (HY-17037). Pirenzepine (LS 519) dihydrochloride is a selective M1 mAChR (muscarinic acetylcholine receptor) antagonist. Pirenzepine dihydrochloride reduces gastric acid secretion and reduces muscle spasm, can be used in peptic ulcers research. Pirenzepine dihydrochloride shows anti-proliferative activity to cancer cells .

HY-G0021S

N-Desmethylclozapine-d8

N-Desmethylclozapine-d₈ is the deuterium labeled N-Desmethylclozapine. N-Desmethylclozapine is a major active metabolite of the atypical antipsychotic agent Clozapine. N-Desmethylclozapine is a potent, allosteric and partial M1 receptors agonist (EC₅₀=115 nM) and is able to potentiate hippocampal N-methyl-d-aspartate (NMDA) receptor currents through M1 receptor activation. N-Desmethylclozapine is also a δ-opioid agonist .

HY-G0021S1

N-Desmethylclozapine-d8 hydrochloride

N-Desmethylclozapine-d₈ (hydrochloride) is the deuterium labeled N-Desmethylclozapine hydrochloride. N-Desmethylclozapine hydrochloride is a major active metabolite of the atypical antipsychotic agent Clozapine. N-Desmethylclozapine hydrochloride is a potent, allosteric and partial M1 receptors agonist (EC₅₀=115 nM) and is able to potentiate hippocampal N-methyl-d-aspartate (NMDA) receptor currents through M1 receptor activation. N-Desmethylclozapine hydrochloride is also a δ-opioid agonist .

HY-W748758

(Z)-Thiothixene-d8

(Z)-Thiothixene-d₈ (NSC 108165-d₈; Navan-d₈; Navane-d₈) is the deuterium labeled Thiothixene (HY-A0139). Thiothixene is a typical antipsychotic. It selectively binds to dopamine D2 over D1, D3, and D4 receptors (Kis=0.417, 338, 186.2, and 363.1 nM, respectively). Thiothixene also binds to various serotonin (5-HT), histamine H1, α1- and α2-adrenergic, muscarinic acetylcholine, and sigma receptors (Kis=15-5,754 nM) as well as the dopamine, norepinephrine, and serotonin transporters (Kis=3.16-30 μM). In vivo, thiothixene reduces spontaneous and amphetamine-induced locomotor activity in rats. It enhances latent inhibition, as measured by a decreased lick latency in response to light and foot shock stimuli, which is a measure of selective attention in rats.3 Thiothixene also increases competitive behavior in submissive mice, indicating antidepressant-like behavior.

HY-14740S

Elvitegravir-d8
Elvitegravir-d₈ is deuterium labeled Elvitegravir. Elvitegravir (GS-9137; JTK-303; D06677) is an HIV integrase inhibitor for HIV-1IIIB, HIV-2EHO and HIV-2ROD with IC50 of 0.7 nM, 2.8 nM and 1.4 nM, respectively.

HY-17037S

Pirenzepine-d8
Pirenzepine-d₈ is the deuterium labeled Pirenzepine dihydrochloride. Pirenzepine dihydrochloride (LS519) is a selective M1 muscarinic receptor antagonist.

HY-50896S3

Erlotinib-d8

Erlotinib-d₈ (CP-358774-d₈) is deuterium labeled Erlotinib. Erlotinib (CP-358774) is a directly acting EGFR tyrosine kinase inhibitor, with an IC₅₀ of 2 nM for human EGFR. Erlotinib reduces EGFR autophosphorylation in intact tumor cells with an IC₅₀ of 20 nM. Erlotinib is used for the treatment of non-small cell lung cancer . Erlotinib is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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