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DL-2-Aminopropionic acid-d<sub>7</sub>

" in MedChemExpress (MCE) Product Catalog:

4239

Inhibitors & Agonists

10

Biochemical Assay Reagents

47

Peptides

1

Inhibitory Antibodies

16

Natural
Products

11

Recombinant Proteins

4120

Isotope-Labeled Compounds

4

Antibodies

17

Click Chemistry

3

Oligonucleotides

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N2362
    DL-Alanine

    DL-2-Aminopropionic acid

    		 Endogenous Metabolite Metabolic Disease
    DL-alanine, an orally active amino acid, is the racemic compound of L- and D-alanine. DL-alanine is employed both as a reducing and a capping agent, used with silver nitrate aqueous solutions for the production of nanoparticles. DL-alanine can be used for the research of transition metals chelation, such as Cu(II), Zn(II), Cd(11). DL-alanine, a sweetener, is classed together with glycine and sodium saccharin. DL-alanine plays a key role in the glucose-alanine cycle between tissues and liver [2] .
    DL-Alanine
  • HY-N2362S2
    DL-Alanine-d3

    DL-2-Aminopropionic acid-d<sub>3sub>

    		 Endogenous Metabolite Metabolic Disease
    DL-Alanine-d3 is the deuterium labeled DL-Alanine. DL-alanine, an amino acid, is the racemic compound of L- and D-alanine. DL-alanine is employed both as a reducing and a capping agent, used with silver nitrate aqueous solutions for the production of nanoparticles. DL-alanine can be used for the research of transition metals chelation, such as Cu(II), Zn(II), Cd(11). DL-alanine, a sweetener, is classed together with glycine, and sodium saccharin. DL-alanine plays a key role in the glucose-alanine cycle between tissues and liver [2] .
    DL-Alanine-d3
  • HY-N2362S
    DL-Alanine-13C-1

    DL-2-Aminopropionic acid-13C-1

    		 Endogenous Metabolite Metabolic Disease
    DL-Alanine- 13C-1 is the 13C-labeled DL-Alanine. DL-alanine, an amino acid, is the racemic compound of L- and D-alanine. DL-alanine is employed both as a reducing and a capping agent, used with silver nitrate aqueous solutions for the production of nanoparticles. DL-alanine can be used for the research of transition metals chelation, such as Cu(II), Zn(II), Cd(11). DL-alanine, a sweetener, is classed together with glycine, and sodium saccharin. DL-alanine plays a key role in the glucose-alanine cycle between tissues and liver [2] .
    DL-Alanine-13C-1
  • HY-N2362S1
    DL-Alanine-13C-3

    DL-2-Aminopropionic acid-13C-3

    		 Isotope-Labeled Compounds Endogenous Metabolite Metabolic Disease
    DL-Alanine- 13C-3 is the 13C-labeled DL-Alanine. DL-alanine, an amino acid, is the racemic compound of L- and D-alanine. DL-alanine is employed both as a reducing and a capping agent, used with silver nitrate aqueous solutions for the production of nanoparticles. DL-alanine can be used for the research of transition metals chelation, such as Cu(II), Zn(II), Cd(11). DL-alanine, a sweetener, is classed together with glycine, and sodium saccharin. DL-alanine plays a key role in the glucose-alanine cycle between tissues and liver [2] .
    DL-Alanine-13C-3
  • HY-N2362S8
    DL-Alanine-d7

    DL-2-Aminopropionic acid-d<sub>7sub>

    		 Isotope-Labeled Compounds Metabolic Disease
    DL-Alanine-d7 (DL-2-Aminopropionic acid-d7) is deuterium labeled DL-Alanine. DL-alanine, an orally active amino acid, is the racemic compound of L- and D-alanine. DL-alanine is employed both as a reducing and a capping agent, used with silver nitrate aqueous solutions for the production of nanoparticles. DL-alanine can be used for the research of transition metals chelation, such as Cu(II), Zn(II), Cd(11). DL-alanine, a sweetener, is classed together with glycine and sodium saccharin. DL-alanine plays a key role in the glucose-alanine cycle between tissues and liver [2] .
    DL-Alanine-d7
  • HY-N2362S9
    DL-Alanine-13C2,15N

    DL-2-Aminopropionic acid-13C<sub>2sub>,15N<sub>2sub>

    		 Isotope-Labeled Compounds Endogenous Metabolite Metabolic Disease
    DL-Alanine- 13C2, 15N (DL-2-Aminopropionic acid- 13C2, 15N) is 13C and 15N labeled DL-Alanine. DL-alanine, an orally active amino acid, is the racemic compound of L- and D-alanine. DL-alanine is employed both as a reducing and a capping agent, used with silver nitrate aqueous solutions for the production of nanoparticles. DL-alanine can be used for the research of transition metals chelation, such as Cu(II), Zn(II), Cd(11). DL-alanine, a sweetener, is classed together with glycine and sodium saccharin. DL-alanine plays a key role in the glucose-alanine cycle between tissues and liver [2] .
    DL-Alanine-13C2,15N
  • HY-N2362S5
    DL-Alanine-15N

    DL-2-Aminopropionic acid-15N

    		 Endogenous Metabolite Metabolic Disease
    DL-Alanine- 15N is the 15N labeled DL-Alanine . DL-alanine, an amino acid, is the racemic compound of L- and D-alanine. DL-alanine is employed both as a reducing and a capping agent, used with silver nitrate aqueous solutions for the production of nanoparticles. DL-alanine can be used for the research of transition metals chelation, such as Cu(II), Zn(II), Cd(11). DL-alanine, a sweetener, is classed together with glycine, and sodium saccharin. DL-alanine plays a key role in the glucose-alanine cycle between tissues and liver [2] [7].
    DL-Alanine-15N
  • HY-RS13999
    SUB1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    SUB1 Human Pre-designed siRNA Set A contains three designed siRNAs for SUB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    SUB1 Human Pre-designed siRNA Set A
    SUB1 Human Pre-designed siRNA Set A
  • HY-RS18793
    Sub1 Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Sub1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Sub1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Sub1 Mouse Pre-designed siRNA Set A
    Sub1 Mouse Pre-designed siRNA Set A
  • HY-RS25282
    Sub1 Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Sub1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Sub1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Sub1 Rat Pre-designed siRNA Set A
    Sub1 Rat Pre-designed siRNA Set A
  • HY-146227
    DNA topoisomerase II inhibitor 1

    		Topoisomerase Apoptosis Cancer
    DNA topoisomerase II inhibitor 1 (compound 8ed) is a potent DNA topoisomerase II inhibitor. DNA topoisomerase II inhibitor 1 shows anti-proliferative activity. DNA topoisomerase II inhibitor 1 induces apoptosis and cell cycle arrest at sub G1 phase .
    DNA topoisomerase II inhibitor 1
  • HY-41463S
    4-(Butylamino)benzoic acid-d7

    4-(Butylamino)benzoic acid-d<sub>7sub>; NSC 44300-d<sub>7sub>; p-Butylaminobenzoic acid-d<sub>7sub>

    		 Isotope-Labeled Compounds Others
    4-(Butylamino)benzoic acid-d7 is the deuterium labeled 4-(Butylamino)benzoic acid[1].
    4-(Butylamino)benzoic acid-d7
  • HY-N2334AS
    Glycochenodeoxycholic acid-d7 sodium

    Chenodeoxycholylglycine-d<sub>7sub> sodium; Sodium glycochenodeoxycholate-d<sub>7sub>

    		 Isotope-Labeled Compounds Endogenous Metabolite Apoptosis Cancer
    Glycochenodeoxycholic acid-d7 (sodium) is the deuterium labeled Glycochenodeoxycholic acid (sodium salt). Glycochenodeoxycholic acid sodium salt (Chenodeoxycholylglycine sodium salt) is a bile acid formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. Glycochenodeoxycholic acid sodium salt (Chenodeoxycholylglycine sodium salt) induces hepatocyte apoptosis [2].
    Glycochenodeoxycholic acid-d7 sodium
  • HY-15027S4
    5-Aminosalicylic acid-d7

    5-ASA-d<sub>7sub>; Mesalamie-d<sub>7sub>; Mesalazie-d<sub>7sub>

    		 Isotope-Labeled Compounds PPAR PAK Endogenous Metabolite NF-κB Inflammation/Immunology Cancer
    5-Aminosalicylic acid-d7 (5-ASA-d7; Mesalamie-d7; Mesalazie-d7) is deuterium labeled 5-Aminosalicylic Acid. 5-Aminosalicylic acid (Mesalamine) acts as a specific PPARγ agonist and also inhibits p21-activated kinase 1 (PAK1) and NF-κB. 5-Aminosalicylic acid can inhibit the activity of osteopontin (OPN) .
    5-Aminosalicylic acid-d7
  • HY-W017387S3
    α-Ketoisocaproic acid-d7

    4-Methyl-2-oxopentanoate-d<sub>7sub>; 2-Ketoisocaproic acid-d<sub>7sub>

    		 Isotope-Labeled Compounds Others
    α-Ketoisocaproic acid-d7 is the deuterium labeled α-Ketoisocaproic acid .
    α-Ketoisocaproic acid-d7
  • HY-18569S3
    3-Indoleacetic acid-d7

    Indole-3-acetic acid-d<sub>7sub>; 3-IAA-d<sub>7sub>

    		 Isotope-Labeled Compounds Endogenous Metabolite Metabolic Disease
    3-Indoleacetic acid-d7 is the deuterium labeled 3-Indoleacetic acid (HY-18569). 3-Indoleacetic acid (Indole-3-acetic acid) is the most common natural plant growth hormone of the auxin class. It can be added to cell culture medium to induce plant cell elongation and division .
    3-Indoleacetic acid-d7
  • HY-10844S1
    Pretomanid-d5

    PA-824-d<sub>5sub>; (S)-PA 824-d<sub>5sub>

    		 Antibiotic Bacterial Isotope-Labeled Compounds Infection Cancer
    Pretomanid-d5 is deuterated labeled Pretomanid (HY-10844). Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 μg/mL.
    Pretomanid-d5
  • HY-P10215
    Ac-{Cpg}-Thr-Ala-{Ala(CO)}-Asp-{Cpg}-NH2

    		Parasite Infection
    Ac-{Cpg}-Thr-Ala-{Ala(CO)}-Asp-{Cpg}-NH2 (compound 40) is a potent Plasmodium subtilisin-like protease 1 (SUB1) inhibitor. SUB1-IN-1 shows IC50 values of 12 nM and 10 nM against P. vivax and P. falciparum SUB1 (Pv- and PfSUB1), respectively .
    Ac-{Cpg}-Thr-Ala-{Ala(CO)}-Asp-{Cpg}-NH2
  • HY-10585AS
    Valproic acid-d7 sodium

    Sodium Valproate-d<sub>7sub>(sodium)

    		 Isotope-Labeled Compounds HDAC Autophagy Mitophagy HIV Notch Endogenous Metabolite Cancer
    Valproic acid-d7 (sodium) is the deuterium labeled Valproic acid (sodium salt). Valproic acid sodium salt (Sodium Valproate) is an HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid sodium salt activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid sodium salt is used in the treatment of epilepsy, bipolar disorder and prevention of migraine headaches [2].
    Valproic acid-d7 sodium
  • HY-41494S
    O-Toluic acid-d7

    2-Methylbenzoic acid-d<sub>7sub>

    		 Isotope-Labeled Compounds Endogenous Metabolite Others
    O-Toluic acid-d7 is the deuterium labeled o-Toluic acid . o-Toluic acid (2-Methylbenzoic acid) is a benzoic acid substituted by a methyl group at position 2. O-Toluic acid plays a role as a xenobiotic metabolite.
    O-Toluic acid-d7
  • HY-76547S1
    p-Toluic acid-d7

    4-Methylbenzoic acid-d<sub>7sub>

    		 Endogenous Metabolite Others
    p-Toluic acid-d7 is the deuterium labeled p-Toluic acid . p-Toluic acid (4-Methylbenzoic acid) is a substituted benzoic acid and can be used as an intermediate for the synthesis of para-aminomethylbenzoic acid (PAMBA), p-tolunitrile, etc.
    p-Toluic acid-d7
  • HY-N0610S1
    trans-Cinnamic acid-d7

    trans-3-Phenylacrylic acid-d<sub>7sub>

    		 Bacterial Endogenous Metabolite Infection
    trans-Cinnamic acid-d7 is the deuterium labeled trans-Cinnamic acid . trans-Cinnamic acid is a natural antimicrobial, with minimal inhibitory concentration (MIC) of 250 μg/mL against fish pathogen A. sobria, SY-AS1 [2].
    trans-Cinnamic acid-d7
  • HY-107327S
    Carazolol-d7

    (±)-Carazolol-d<sub>7sub>; DL-Carazolol-d<sub>7sub>; Suacron-d<sub>7sub>

    		 Isotope-Labeled Compounds Adrenergic Receptor Cardiovascular Disease
    Carazolol-d7 is the deuterium labeled Carazolol (HY-107327). Carazolol is a highly potent antagonist of β1/β2 adrenoceptor. Carazolol is also a potent, selective β3-adrenoceptor agonist. Carazolol can be used in the research of hypertension .
    Carazolol-d7
  • HY-N0006S
    Demethoxycurcumin-d7

    Curcumin II-d<sub>7sub>; Desmethoxycurcumin-d<sub>7sub>; Monodemethoxycurcumin-d<sub>7sub>

    		 Isotope-Labeled Compounds Apoptosis Autophagy Bacterial Inflammation/Immunology Cancer
    Demethoxycurcumin-d7 is the deuterium labeled Demethoxycurcumin. Demethoxycurcumin(Curcumin II), a major active curcuminoid, possess anti-inflammatory properties; also exert cytotoxic effects in human cancer cells via induction of apoptosis.
    Demethoxycurcumin-d7
  • HY-B0584S2
    Travoprost-d7

    Fluprostenol isopropyl ester-<sub>7sub>; AL6221-<sub>7sub>; Flu-Ipr-<sub>7sub>

    		 Isotope-Labeled Compounds Prostaglandin Receptor Cardiovascular Disease Endocrinology
    Travoprost-d7 (Fluprostenol isopropyl ester-d7) is deuterium labeled Travoprost. Travoprost (Fluprostenol isopropyl ester), an isopropyl ester proagent, is a high affinity, selective FP prostaglandin full receptor agonist. Travoprost has the ocular hypotensive efficacy and has the potential for glaucoma and ocular hypertension .
    Travoprost-d7
  • HY-66005S2
    Acetaminophen-d7

    Paracetamol-d<sub>7sub>; 4-Acetamidophenol-d<sub>7sub>; 4'-Hydroxyacetanilide-d<sub>7sub>

    		 COX Endogenous Metabolite Histone Acetyltransferase Inflammation/Immunology
    Acetaminophen-d7 is the deuterium labeled Acetaminophen. Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM; is a widely used antipyretic and analgesic agent. Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor.
    Acetaminophen-d7
  • HY-B0389S6
    D-Glucose-d7

    Glucose-d<sub>7sub>; D-(+)-Glucose-d<sub>7sub>; Dextrose-d<sub>7sub>

    		 Isotope-Labeled Compounds Endogenous Metabolite Metabolic Disease
    D-Glucose-d77 is the deuterium labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response .
    D-Glucose-d7
  • HY-D0711S2
    Indocyanine green-d7

    Foxgreen-d<sub>7sub>; IC Green-d<sub>7sub>; Cardiogreen-d<sub>7sub>

    		 Isotope-Labeled Compounds Fluorescent Dye Others
    Indocyanine green-d7 (Foxgreen-d7) is the deuterium labeled Indocyanine green (HY-D0711). Indocyanine green is a low toxicic fluorescent agent that has been widely used in medical diagnostics, such as determining cardiac output, hepatic function, and liver blood flow, and for ophthalmic angiography .
    Indocyanine green-d7
  • HY-107352S
    Fosfenopril-d7

    Fosinoprilat-d<sub>7sub>; Fosinoprilic acid-d<sub>7sub>; SQ 27519-d<sub>7sub>

    		 Angiotensin-converting Enzyme (ACE) Interleukin Related NF-κB TNF Receptor Toll-like Receptor (TLR) Isotope-Labeled Compounds Others
    Fosfenopril-d7 is deuterium labeled Fosfenopril.
    Fosfenopril-d7
  • HY-W012722BS
    4-Methyl-2-oxopentanoic acid-d7 sodium

    α-Ketoisocaproic acid-d<sub>7sub> sodium

    		 Endogenous Metabolite Isotope-Labeled Compounds Neurological Disease Metabolic Disease
    4-Methyl-2-oxopentanoic acid-d7 (α-Ketoisocaproic acid-d7) sodium is the deuterium labeled 4-Methyl-2-oxopentanoic acid (HY-W012722).4-Methyl-2-oxopentanoic acid is a metabolite of L-leucine and is involved in energy metabolism. 4-Methyl-2-oxopentanoic acid increases endoplasmic reticulum stress, promotes lipid accumulation in preadipocytes and insulin resistance by impairing mTOR and autophagy signaling pathways [2].
    4-Methyl-2-oxopentanoic acid-d7 sodium
  • HY-12057S1
    Vemurafenib-d7

    PLX4032-d<sub>7sub>; RG7204-d<sub>7sub>; RO5185426-d<sub>7sub>

    		 Isotope-Labeled Compounds Raf Autophagy Cancer
    Vemurafenib-d7 is deuterium labeled Vemurafenib. Vemurafenib (PLX4032) is a first-in-class, selective, potent inhibitor of B-RAF kinase, with IC50s of 31 and 48 nM for RAFV600E and c-RAF-1, respectively . Vemurafenib induces cell autophagy .
    Vemurafenib-d7
  • HY-15149S2
    Romidepsin-d7

    FK 228-d<sub>7sub>; FR 901228-d<sub>7sub>; NSC 630176-d<sub>7sub>

    		 Isotope-Labeled Compounds HDAC Apoptosis Cancer
    Romidepsin-d7 (FK 228-d7) is deuterium labeled Romidepsin. Romidepsin (FK 228) is a Histone deacetylase (HDAC) inhibitor with anti-tumor activities. Romidepsin (FK 228) inhibits HDAC1, HDAC2, HDAC4, and HDAC6 with IC50s of 36 nM, 47 nM, 510 nM and 1.4 μM, respectively . Romidepsin (FK 228) is produced by Chromobacterium violaceum, induces cell G2/M phase arrest and apoptosis [2].
    Romidepsin-d7
  • HY-Y0376S
    DMPA-d7

    Bis-MPA-d<sub>7sub>; Dimethylolpropionic acid-d<sub>7sub>; Nikkamer PA-d<sub>7sub>

    		 Isotope-Labeled Compounds Others
    DMPA-d7 is the deuterium labeled DMPA .
    DMPA-d7
  • HY-W653985
    Cortodoxone-d7

    11-Deoxycortisol-d<sub>7sub>; Cortexolone-d<sub>7sub>; Reichstein's substance S-d<sub>7sub>

    		 Isotope-Labeled Compounds Glucocorticoid Receptor Endogenous Metabolite Inflammation/Immunology Endocrinology
    Cortodoxone-d7 (11-Deoxycortisol-d7) is a deuterium labeled Cortodoxone (HY-77839). Cortodoxone (11-Deoxycortisol; cortexolone) is a glucocorticoid steroid hormone and also is a glucocorticoid antagonist. Cortodoxone increases tryptophan oxygenase (TO) activity and induces the secretion of corticosterone. Cortodoxone regulates T cell proliferation and activation [2].
    Cortodoxone-d7
  • HY-N7745S
    Glucosylsphingosine-d7

    Glucopsychosine-d<sub>7sub>; Lyso-Gb1-d<sub>7sub>; Lyso-GL1-d<sub>7sub>

    		 Isotope-Labeled Compounds Others
    Glucosylsphingosine-d7 is deuterium labeled Glucosylsphingosine.
    Glucosylsphingosine-d7
  • HY-Y1309S1
    1-Naphthol-d7

    Furro ER-d<sub>7sub>; NSC 9586-d<sub>7sub>; Nako TRB-d<sub>7sub>

    		 Isotope-Labeled Compounds Others
    1-Naphthol-d7 is the deuterium labeled Naphthol .
    1-Naphthol-d7
  • HY-107370S
    Atomoxetine-d7

    Tomoxetine-d<sub>7sub>; (R)-Tomoxetine-d<sub>7sub>

    		 Isotope-Labeled Compounds Serotonin Transporter Sodium Channel Neurological Disease Cancer
    Atomoxetine-d7 (Tomoxetine-d7) is deuterium labeled Atomoxetine. Atomoxetine (Tomoxetine) is a selective noradrenaline reuptake inhibitor with Ki values of 5, 77 and 1451 nM for norepinephrine (NE), serotonin (5-HT) and dopamine (DA) transporters, respectively. Atomoxetine (Tomoxetine) increases of DAEX and NEEX in the PFC and enhances catecholaminergic neurotransmission. Atomoxetine (Tomoxetine) is a potent Na + channels (VGSCs) blocker. Atomoxetine (Tomoxetine) can be used for attention-deficit hyperactivity disorder (ADHD) research [2] .
    Atomoxetine-d7
  • HY-135328S
    Norverapamil-d7

    (±)-Norverapamil-d<sub>7sub>; D591-d<sub>7sub>

    		 Isotope-Labeled Compounds Calcium Channel P-glycoprotein Drug Metabolite Cardiovascular Disease
    Norverapamil-d7 is a deuterium labeled Norverapamil ((±)-Norverapamil). Norverapamil, an N-demethylated metabolite of Verapamil, is a L-type calcium channel blocker and a P-glycoprotein (P-gp) function inhibitor [2].
    Norverapamil-d7
  • HY-135328AS
    Norverapamil-d7 hydrochloride

    (±)-Norverapamil-d<sub>7sub> hydrochloride; D591-d<sub>7sub> hydrochloride

    		 Isotope-Labeled Compounds Calcium Channel Cardiovascular Disease
    Norverapamil-d7 (hydrochloride) is a deuterium labeled Norverapamil. Norverapamil ((±)-Norverapamil), an N-demethylated metabolite of Verapamil, is a L-type calcium channel blocker and a P-glycoprotein (P-gp) function inhibitor [2].
    Norverapamil-d7 hydrochloride
  • HY-B1438S2
    Canrenone-d7

    Aldadiene-d<sub>7sub> ; SC9376-d<sub>7sub>

    		 Isotope-Labeled Compounds Mineralocorticoid Receptor Endogenous Metabolite Cardiovascular Disease
    Canrenone-d7 (Aldadiene-d7 ) is deuterium labeled Canrenone. Canrenone (Aldadiene) is an aldosterone antagonist extensively used as a diuretic agent.
    Canrenone-d7
  • HY-17025S
    Rifabutin-d7

    Ansamycin-d<sub>7sub>; LM-427-d<sub>7sub>

    		 Isotope-Labeled Compounds Bacterial Antibiotic Infection
    Rifabutin-d7 is the deuterium labeled Rifabutin. Rifabutin (Ansamycin) is a semisynthetic ansamycin antibiotic with potent antimycobacterial properties. Rifabutin inhibits DNA-dependent RNA polymerase.
    Rifabutin-d7
  • HY-107855S
    DL-Mevalonolactone-d7

    (±)-Mevalonolactone-d<sub>7sub>; Mevalolactone-d<sub>7sub>

    		 Endogenous Metabolite Metabolic Disease
    DL-Mevalonolactone-d7 is the deuterium labeled DL-Mevalonolactone. DL-Mevalonolactone ((±)-Mevalonolactone) is the δ-lactone form of mevalonic acid, a precursor in the mevalonate pathway. DL-Mevalonolactone (Mevalonolactone) decreases mitochondrial membrane potential (?Ψm), NAD(P)H content and the capacity to retain Ca2+ in the brain, besides inducing mitochondrial swelling [2].
    DL-Mevalonolactone-d7
  • HY-41700S3
    D-Alanine-d7

    (R)-Alanine-d<sub>7sub>; Ba 2776-d<sub>7sub>; D-α-Alanine-d<sub>7sub>

    		 Endogenous Metabolite Neurological Disease
    D-Alanine-d7 is the deuterium labeled D-Alanine. D-Alanine is a weak GlyR (inhibitory glycine receptor) and PMBA agonist, with an EC50 of 9 mM for GlyR.
    D-Alanine-d7
  • HY-W700392
    IMPDH-IN-2

    		IMPDH Cancer
    IMPDH-IN-2 (compound 2) is an inhibitor of inosine monophosphate dehydrogenase (IMPDH) with IC50 for IMPDH I and IMPDH II >Values are 0.15 and 0.17 μM, respectively. IMPDH-IN-2 has antitumor activity .
    IMPDH-IN-2
  • HY-109037S4
    Mavacamten-d7

    MYK461-d<sub>7sub>; SAR439152-d<sub>7sub>

    		 Isotope-Labeled Compounds Myosin Cardiovascular Disease
    Mavacamten-d7 (MYK461-d7) is deuterium labeled Mavacamten. Mavacamten (MYK461) is an orally active modulator of cardiac myosin, with IC50s of 490, 711 nM for bovine cardiac and human cardiac, respectively.
    Mavacamten-d7
  • HY-B0391S2
    Naftopidil-d7

    KT-611-d<sub>7sub>; BM-15275-d<sub>7sub>

    		 Isotope-Labeled Compounds Adrenergic Receptor Cardiovascular Disease Endocrinology
    Naftopidil-d7 (KT-611-d7 ) is deuterium labeled Naftopidil. Naftopidil (KT-611) is is a selective alpha1-adrenoceptor antagonist, with Kis of 3.7 nM, 20 nM and 1.2 nM for the cloned human α1a-, α1b- and α1d-adrenoceptor subtypes, respectively. Naftopidil has antiproliferative effects. Naftopidil can be used for the research of prostate hyperplasia [2].
    Naftopidil-d7
  • HY-50898S1
    Lapatinib-d7 dihydrochloride

    GW572016-dd<sub>7sub> dihydrochloride; GW2016-dd<sub>7sub> dihydrochloride

    		 Isotope-Labeled Compounds EGFR Autophagy Ferroptosis Cancer
    Lapatinib-d7 dihydrochloride is the deuterium labeled Lapatinib dihydrochloride. Lapatinib (GW572016) dihydrochloride is a potent inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively .
    Lapatinib-d7 dihydrochloride
  • HY-135853S
    Molnupiravir-d7

    EIDD-2801-d<sub>7sub>; MK-4482-d<sub>7sub>

    		 SARS-CoV Influenza Virus Inflammation/Immunology
    Molnupiravir-d7 is the deuterium labeled Molnupiravir. Molnupiravir (EIDD-2801) is an orally bioavailable prodrug of the ribonucleoside analog EIDD-1931. Molnupiravir has broad spectrum antiviral activity against influenza virus and multiple coronaviruses, such as SARS-CoV-2, MERS-CoV, SARS-CoV. Molnupiravir has the potential for the research of COVID-19, and seasonal and pandemic influenza [2].
    Molnupiravir-d7
  • HY-B0202AS
    Irbesartan-d7 hydrochloride

    SR-47436-d<sub>7sub> hydrochloride; BMS-186295-d<sub>7sub> hydrochloride

    		 Apoptosis Angiotensin Receptor Isotope-Labeled Compounds Neurological Disease Metabolic Disease
    Irbesartan-d7 hydrochloride is deuterated labeled Irbesartan hydrochloride (HY-B0202A). Irbesartan (SR-47436) hydrochloride is an orally active Ang II type 1 (AT1) receptor blocker (ARB). Irbesartan hydrochloride can relax the blood vessels, low blood pressure and increase the supply of blood and oxygen to the heart. Irbesartan hydrochloride can be used for the research of high blood pressure, heart failure, and diabetic kidney disease .
    Irbesartan-d7 hydrochloride
  • HY-30237S
    (R)-Roscovitine-d7

    Seliciclib-d<sub>7sub>; CYC202-d<sub>7sub>

    		 CDK Isotope-Labeled Compounds Cancer
    (R)-Roscovitine-d7 (Seliciclib-d7; CYC202-d7) is deuterium-labeled (R)-Roscovitine (HY-30237) .
    (R)-Roscovitine-d7

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