rac 3,4-Dihydroxymandelic Acid-d₃

Cat. No.: HY-W653885: Data Sheet Handling Instructions
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rac 3,4-Dihydroxymandelic Acid-d₃ is deuterium labeled 3,4-Dihydroxymandelic acid. 3,4-Dihydroxymandelic acid is a metabolite of norepinephrine.

For research use only. We do not sell to patients.

rac 3,4-Dihydroxymandelic Acid-</sub>d<sub>3</sub> Chemical Structure

rac 3,4-Dihydroxymandelic Acid-d₃ Chemical Structure

Size	Stock	Quantity
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

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Other Forms of rac 3,4-Dihydroxymandelic Acid-d₃:

3,4-Dihydroxymandelic acid In-stock

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Purity & Documentation
References
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Description

rac 3,4-Dihydroxymandelic Acid-d₃ is deuterium labeled 3,4-Dihydroxymandelic acid. 3,4-Dihydroxymandelic acid is a metabolite of norepinephrine^[1].

Molecular Weight

187.16

Formula

C₈H₅D₃O₅

Unlabeled CAS

775-01-9

SMILES

OC1=C(C([2H])=C(C([2H])=C1O)C(C(O)=O)O)[2H]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility

In Vitro:

DMSO : 83.33 mg/mL (445.23 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.3430 mL	26.7151 mL	53.4302 mL
5 mM	1.0686 mL	5.3430 mL	10.6860 mL
10 mM	0.5343 mL	2.6715 mL	5.3430 mL

View the Complete Stock Solution Preparation Table

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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In Vivo Dissolution Calculator

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Working solution concentration: mg/mL

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]

[2]. Sule N, et al. The Norepinephrine Metabolite 3,4-Dihydroxymandelic Acid Is Produced by the Commensal Microbiota and Promotes Chemotaxis and Virulence Gene Expression in Enterohemorrhagic Escherichia coli. Infect Immun. 2017 Sep 20;85(10). [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	5.3430 mL	26.7151 mL	53.4302 mL	133.5755 mL
	5 mM	1.0686 mL	5.3430 mL	10.6860 mL	26.7151 mL
	10 mM	0.5343 mL	2.6715 mL	5.3430 mL	13.3576 mL
	15 mM	0.3562 mL	1.7810 mL	3.5620 mL	8.9050 mL
	20 mM	0.2672 mL	1.3358 mL	2.6715 mL	6.6788 mL
	25 mM	0.2137 mL	1.0686 mL	2.1372 mL	5.3430 mL
	30 mM	0.1781 mL	0.8905 mL	1.7810 mL	4.4525 mL
	40 mM	0.1336 mL	0.6679 mL	1.3358 mL	3.3394 mL
	50 mM	0.1069 mL	0.5343 mL	1.0686 mL	2.6715 mL
	60 mM	0.0891 mL	0.4453 mL	0.8905 mL	2.2263 mL
	80 mM	0.0668 mL	0.3339 mL	0.6679 mL	1.6697 mL
	100 mM	0.0534 mL	0.2672 mL	0.5343 mL	1.3358 mL