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  3. Glycodeoxycholic acid-d5

Glycodeoxycholic acid-d5 is deuterium labeled Glycodeoxycholic Acid. Glycodeoxycholic Acid is a natural product found in Streptomyces nigricans, Trypanosoma brucei and C. elegans. Glycodeoxycholic Acid induces hepatocyte necrosis and autophagy in patients with obstructive cholestasis.

For research use only. We do not sell to patients.

Glycodeoxycholic acid-d<sub>5</sub> Chemical Structure

Glycodeoxycholic acid-d5 Chemical Structure

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Description

Glycodeoxycholic acid-d5 is deuterium labeled Glycodeoxycholic Acid. Glycodeoxycholic Acid is a natural product found in Streptomyces nigricans, Trypanosoma brucei and C. elegans. Glycodeoxycholic Acid induces hepatocyte necrosis and autophagy in patients with obstructive cholestasis[1][2][3][4].

Molecular Weight

454.65

Formula

C26H38D5NO5

Unlabeled CAS
SMILES

[H][C@@]12C([2H])([C@@]([2H])(C([2H])(C[C@@]1([C@H](C3CC2)C[C@H]([C@]4([C@]3(CC[C@@H]4[C@@H](CCC(NCC(O)=O)=O)C)[H])C)O)C)[2H])O)[2H]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (274.94 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1995 mL 10.9975 mL 21.9949 mL
5 mM 0.4399 mL 2.1995 mL 4.3990 mL
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This equation is commonly abbreviated as: C1V1 = C2V2

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Purity & Documentation
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Complete Stock Solution Preparation Table

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.1995 mL 10.9975 mL 21.9949 mL 54.9874 mL
5 mM 0.4399 mL 2.1995 mL 4.3990 mL 10.9975 mL
10 mM 0.2199 mL 1.0997 mL 2.1995 mL 5.4987 mL
15 mM 0.1466 mL 0.7332 mL 1.4663 mL 3.6658 mL
20 mM 0.1100 mL 0.5499 mL 1.0997 mL 2.7494 mL
25 mM 0.0880 mL 0.4399 mL 0.8798 mL 2.1995 mL
30 mM 0.0733 mL 0.3666 mL 0.7332 mL 1.8329 mL
40 mM 0.0550 mL 0.2749 mL 0.5499 mL 1.3747 mL
50 mM 0.0440 mL 0.2199 mL 0.4399 mL 1.0997 mL
60 mM 0.0367 mL 0.1833 mL 0.3666 mL 0.9165 mL
80 mM 0.0275 mL 0.1375 mL 0.2749 mL 0.6873 mL
100 mM 0.0220 mL 0.1100 mL 0.2199 mL 0.5499 mL
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Glycodeoxycholic acid-d5
Cat. No.:
HY-W653999
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