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Ganglioside GM3-d<sub>7</sub>

" in MedChemExpress (MCE) Product Catalog:

4341

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14

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10

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2

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9

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20

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14

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4221

Isotope-Labeled Compounds

12

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17

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3

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Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-114456
    Ganglioside GM3

    		Insulin Receptor Metabolic Disease
    Ganglioside GM3 is a precursor of a-, b-, and c-series gangliosides, interacts with transmembrane receptors such as the epidermal growth factor and insulin receptors, and regulates receptor functions by creating a specialized lipid environment. Ganglioside GM3 is synthesized by GM3 synthase and can be used for the research of hypercholesterolemia .
    Ganglioside GM3
  • HY-152002S
    Ganglioside GM3-d3 ammonium

    		Isotope-Labeled Compounds Others
    Ganglioside GM3-d3 ammonium is a deuterated labeled Ganglioside GM3 ammonium .
    Ganglioside GM3-d3 ammonium
  • HY-114456S
    Ganglioside GM3-d7

    		Isotope-Labeled Compounds Others Metabolic Disease
    Ganglioside GM3-d7 is deuterium labeled Ganglioside GM3. Ganglioside GM3 is a precursor of a-, b-, and c-series gangliosides, interacts with transmembrane receptors such as the epidermal growth factor and insulin receptors, and regulates receptor functions by creating a specialized lipid environment. Ganglioside GM3 is synthesized by GM3 synthase and can be used for the research of hypercholesterolemia [3].
    Ganglioside GM3-d7
  • HY-114456AS
    Ganglioside GM3-d5 Bovine Milk ammonium salt

    		Isotope-Labeled Compounds Others
    Ganglioside GM3-d5 (Bovine Milk ammonium salt) is deuterium labeled Ganglioside GM3 (Bovine Milk ammonium salt).
    Ganglioside GM3-d5 Bovine Milk ammonium salt
  • HY-165665S
    C16 Ganglioside GM3-d9 ammonium salt

    		Isotope-Labeled Compounds Others
    C16 Ganglioside GM3-d9 (ammonium salt) is deuterium labeled C16 Ganglioside GM3 (ammonium salt) .
    C16 Ganglioside GM3-d9 ammonium salt
  • HY-N10511
    GM1a Ganglioside oligosaccharide

    		Others Inflammation/Immunology
    GM1a Ganglioside oligosaccharide is a semisynthetic form of ganglioside GM1. Ganglioside GM1 is the natural receptor for cholera toxin and plays an important role not only in general growth regulation but also in the coupling of hormone-induced responses .
    GM1a Ganglioside oligosaccharide
  • HY-157343A
    GD3 Ganglioside sodium

    		Apoptosis Neurological Disease Cancer
    GD3 Ganglioside sodium is a prominent ganglioside of human melanoma. GD3 Ganglioside sodium is an inducer of mitochondrial permeability. GD3 ganglioside directly targets mitochondria in a bcl-2-controlled fashion. GD3 ganglioside is rapidly synthesized from accumulated ceramide after the clustering of death-inducing receptors and triggers apoptosis .
    GD3 Ganglioside sodium
  • HY-157343
    GD3 Ganglioside

    		Apoptosis Neurological Disease Cancer
    GD3 Ganglioside is a prominent ganglioside of human melanoma. GD3 Ganglioside is an inducer of mitochondrial permeability. GD3 ganglioside directly targets mitochondria in a bcl-2-controlled fashion. GD3 ganglioside is rapidly synthesized from accumulated ceramide after the clustering of death-inducing receptors and triggers apoptosis .
    GD3 Ganglioside
  • HY-157343B
    GD3 Ganglioside ammonium

    		Apoptosis Neurological Disease Cancer
    GD3 Ganglioside ammonium is a prominent ganglioside of human melanoma. GD3 Ganglioside ammonium is an inducer of mitochondrial permeability. GD3 ganglioside ammonium directly targets mitochondria in a bcl-2-controlled fashion. GD3 ganglioside ammonium is rapidly synthesized from accumulated ceramide after the clustering of death-inducing receptors and triggers apoptosis .
    GD3 Ganglioside ammonium
  • HY-P10529
    Ganglioside GM1-binding peptides p3

    		Trk Receptor Infection
    Ganglioside GM1-binding peptides p3 is a synthetic peptide that can specifically bind to the pentasaccharide part of GM1 ganglioside. The dynamic transformation of Ganglioside GM1-binding peptides p3 may play an important role in the function of GM1 as a multiple receptor, such as in the classical pathway of cholera toxin infection. Ganglioside GM1-binding peptides p3 can be used to study the interaction between GM1 and its ligands .
    Ganglioside GM1-binding peptides p3
  • HY-146227
    DNA topoisomerase II inhibitor 1

    		Topoisomerase Apoptosis Cancer
    DNA topoisomerase II inhibitor 1 (compound 8ed) is a potent DNA topoisomerase II inhibitor. DNA topoisomerase II inhibitor 1 shows anti-proliferative activity. DNA topoisomerase II inhibitor 1 induces apoptosis and cell cycle arrest at sub G1 phase .
    DNA topoisomerase II inhibitor 1
  • HY-RS13999
    SUB1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    SUB1 Human Pre-designed siRNA Set A contains three designed siRNAs for SUB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    SUB1 Human Pre-designed siRNA Set A
    SUB1 Human Pre-designed siRNA Set A
  • HY-RS18793
    Sub1 Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Sub1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Sub1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Sub1 Mouse Pre-designed siRNA Set A
    Sub1 Mouse Pre-designed siRNA Set A
  • HY-RS25282
    Sub1 Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Sub1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Sub1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Sub1 Rat Pre-designed siRNA Set A
    Sub1 Rat Pre-designed siRNA Set A
  • HY-N10546
    Ganglioside GM1

    		Others Neurological Disease
    Ganglioside GM1 is a member of the ganglioside family that can be used for neurological disease research. Ganglioside GM1 is a functional tissue receptor for the Cholera Toxin1 .
    Ganglioside GM1
  • HY-10844S1
    Pretomanid-d5

    PA-824-d<sub>5sub>; (S)-PA 824-d<sub>5sub>

    		 Antibiotic Bacterial Isotope-Labeled Compounds Infection Cancer
    Pretomanid-d5 is deuterated labeled Pretomanid (HY-10844). Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 μg/mL.
    Pretomanid-d5
  • HY-P10215
    Ac-{Cpg}-Thr-Ala-{Ala(CO)}-Asp-{Cpg}-NH2

    		Parasite Infection
    Ac-{Cpg}-Thr-Ala-{Ala(CO)}-Asp-{Cpg}-NH2 (compound 40) is a potent Plasmodium subtilisin-like protease 1 (SUB1) inhibitor. SUB1-IN-1 shows IC50 values of 12 nM and 10 nM against P. vivax and P. falciparum SUB1 (Pv- and PfSUB1), respectively .
    Ac-{Cpg}-Thr-Ala-{Ala(CO)}-Asp-{Cpg}-NH2
  • HY-W747597
    Ganglioside GD1b Disodium Salt (Bovine Brain)

    DisialoGanglioside GD1b; Ganglioside C1; Ganglioside G2

    		 Endogenous Metabolite Cancer
    Ganglioside GD1b Disodium Salt (Bovine Brain) (Disialoganglioside GD1b; Ganglioside C1) is an acidic glycosphingolipid containing two sialic acid residues linked to an internal galactose unit. Ganglioside GD1b Disodium Salt tightly packs with cholesterol to form lipid microdomains that modulate intracellular and intercellular signaling events. Concentrations of Ganglioside GD1b Disodium Salt (Bovine Brain) in the human brain increase with age and are positively correlated with pilocytic astrocytoma tumor grade. Ganglioside GD1b Disodium Salt has been detected in various other gliomas, including primitive neuroectodermal tumors, glioblastomas, and anaplastic astrocytomas.
    Ganglioside GD1b Disodium Salt (Bovine Brain)
  • HY-N10546A
    Ganglioside GM1 (bovine) ammonium

    		Endogenous Metabolite Neurological Disease
    Ganglioside GM1 (bovine) ammonium is a member of the ganglioside family that can be used for neurological disease research. Ganglioside GM1 (bovine) ammonium is a functional tissue receptor for the Cholera Toxin1 .
    Ganglioside GM1 (bovine) ammonium
  • HY-166325A
    Ganglioside GD3-d3 ammonium

    		Biochemical Assay Reagents Metabolic Disease
    Ganglioside GD3-d3 ammonium is the deuterium labeled Ganglioside GD3 ammonium. Ganglioside GD3 ammonium is an ester product.
    Ganglioside GD3-d3 ammonium
  • HY-165676AS
    C16 Ganglioside GM2-d9 (d18:1/16:0-d9) ammonium salt

    C16 GM2-dsub>N<sub>; N-CDsub>N<sub>-Palmitoyl-GM2, N-Hexadecaoyl-dsub>N<sub> (13,13,14,14,15,15,16,16,16)-Moosialogaglioside GM2; N-Palmitoyl Moosialogaglioside GM2-d<sub>9sub>

    		 Isotope-Labeled Compounds Others
    C16 Ganglioside GM2-d9 (d18:1/16:0-d9) (C16 GM2-d9) ammonium saltis deuterium labeled C16 Ganglioside GM2 (d18:1/16:0) (ammonium salt) .
    C16 Ganglioside GM2-d9 (d18:1/16:0-d9) ammonium salt
  • HY-165650S
    C16 Ganglioside GM1-d9 (d18:1/16:0) ammonium

    C16-GM1-d<sub>9sub> ammonium; N-Hexadecaoyl-d<sub>9sub> (13,13,14,14,15,15,16,16,16)-moosialogaglioside GM1 ammonium

    		 Isotope-Labeled Compounds Others
    C16 Ganglioside GM1-d9 (d18:1/16:0) (C16 GM1-d9) ammonium salt is deuterium labeled C16 Ganglioside GM1 (d18:1/16:0) (ammonium) .
    C16 Ganglioside GM1-d9 (d18:1/16:0) ammonium
  • HY-148385
    Ganglioside GM2

    		Endogenous Metabolite Integrin FAK Src ERK p38 MAPK Neurological Disease Cancer
    Ganglioside GM2 is a human tumor antigen predominantly found in human tumor cells and fetal brain tissue. As a sialylated glycosphingolipid, Ganglioside GM2 is involved in processes such as cell signaling, adhesion, and motility. Ganglioside GM2 abnormal expression and accumulation are associated with tumors and neurodegenerative disorders. Ganglioside GM2 promotes tumor cell migration and invasion by directly binding to the integrin β1 receptor, activating the FAK/Src/Erk-MAPK signaling pathway, and inducing actin cytoskeleton remodeling [3].
    Ganglioside GM2
  • HY-131139
    Ganglioside GD3 disodium salt

    		Apoptosis Neurological Disease Cancer
    Ganglioside GD3 disodium salt is an acidic glycosphingolipid. Ganglioside GD3 disodium salt inhibits the proliferation of cancer cells, affects the opening of the mitochondrial permeability transition pore (PTPC), induces apoptosis and activates caspase family. Ganglioside GD3 disodium salt can be used in research about cancer and neurodegenerative diseases .
    Ganglioside GD3 disodium salt
  • HY-131139A
    Ganglioside GD3 diammonium

    		Apoptosis Neurological Disease Cancer
    Ganglioside GD3 diammonium is an acidic glycosphingolipid. Ganglioside GD3 diammonium inhibits the proliferation of cancer cells, affects the opening of the mitochondrial permeability transition pore (PTPC), induces apoptosis and activates caspase family. Ganglioside GD3 diammonium can be used in research about cancer and neurodegenerative diseases .
    Ganglioside GD3 diammonium
  • HY-165740
    Ganglioside GD2

    DisialoGanglioside GD2

    		 Biochemical Assay Reagents Cancer
    Ganglioside GD2 (Disialoganglioside GD2), a member of the ganglioside family, is a tumor-associated antigen that is highly expressed in almost all neuroblastomas, as well as in most melanomas and retinoblastomas. Ganglioside GD2 contributes to tumor development by enhancing cell proliferation, motility, migration, adhesion, and invasion. Anti-Ganglioside GD2 strategies hold promise for research in the field of anti-tumor therapy .
    Ganglioside GD2
  • HY-152003S
    Ganglioside GM2-d3 ammonium

    		Isotope-Labeled Compounds Others
    Ganglioside GM2-d3 (ammonium) is the deuterium labeled Ganglioside GM2 (HY-148385). Ganglioside GM2 is a human tumor antigen predominantly found in human tumor cells and fetal brain tissue. As a sialylated glycosphingolipid, Ganglioside GM2 is involved in processes such as cell signaling, adhesion, and motility. Ganglioside GM2 abnormal expression and accumulation are associated with tumors and neurodegenerative disorders. Ganglioside GM2 promotes tumor cell migration and invasion by directly binding to the integrin β1 receptor, activating the FAK/Src/Erk-MAPK signaling pathway, and inducing actin cytoskeleton remodeling [3].
    Ganglioside GM2-d3 ammonium
  • HY-171936
    Ganglioside GM1 ammonium

    GM1 (d18:1/C18:0) ammonium; C18 Ganglioside GM1 (d18:1/18:0) ammonium

    		 Endogenous Metabolite Neurological Disease
    Ganglioside GM1 (ammonium) is a monosialylated ganglioside and the prototypic ganglioside for those containing one sialic acid residue. Ganglioside GM1 (ammonium) is one of the most abundant gangliosides in the brain which provides neuroprotection. Ganglioside GM1 (ammonium) exhibits anti-inflammatory property. Ganglioside GM1 (ammonium) has a well-balanced amphiphilic behavior. Ganglioside GM1 (ammonium) can reduce the fluidity of the plasma membrane that implies a retention and enrichment of the ganglioside in specific membrane domains that are called lipid rafts. Ganglioside GM1 (ammonium) can modify the process of differentiation, amplifies responses to neurotrophic factors, protects against excitatory amino acid-related neurotoxicity. Ganglioside GM1 (ammonium) can alleviate acute nerve cell damage through blocking cytotoxicity and potentiating neurotophic factors. Ganglioside GM1 (ammonium) can be studied in neurodegenerative diseases such as Alzheimer’s disease [1] [2] [3] .
    Ganglioside GM1 ammonium
  • HY-W714151
    Ganglioside ga1

    Gg4cer; AsialoGanglioside GM1; Asialo GM1, Gangliotetraosylceramide; Asialo Ganglioside GM1a [...]; Ganglio-n-tetraosylceramide; Asialo GM1 Ganglioside; AsialoGanglioside gt1b

    		 Biochemical Assay Reagents Metabolic Disease
    Ganglioside ga1 (Gg4cer; Asialoganglioside gm1; Asialo gm1, Gangliotetraosylceramide; Asialo ganglioside gm1a [...]; Ganglio-n-tetraosylceramide; Asialo gm1 ganglioside; Asialoganglioside gt1b) is an ester product.
    Ganglioside ga1
  • HY-146876S
    C18:0 GM1 Ganglioside-d5 ammonium

    		Isotope-Labeled Compounds Others
    C18:0 GM1 Ganglioside-d5 (ammonium) is deuterium labeled C18:0 GM1 Ganglioside (ammonium).
    C18:0 GM1 Ganglioside-d5 ammonium
  • HY-W719338
    Pentane-1,2-diol-d7

    (±)-Pentane-1,2-diol<sub>7sub>; 1,2-Dihydroxypentane<sub>7sub>; 1,2-Pentylene glycol<sub>7sub>; Diol PD<sub>7sub>; Hydrolite 5<sub>7sub>; NSC 513<sub>7sub>; 1,2-Pentanediol<sub>7sub>

    		 Isotope-Labeled Compounds Others
    Pentane-1,2-diol-d7 ((±)-Pentane-1,2-diol-d7; 1,2-Dihydroxypentane-d7; 1,2-Pentylene glycol-d7; Diol PD-d7; Hydrolite 5-d7; NSC 513-d7; 1,2-Pentanediol-d7) is the deuterium labeled Pentane-1,2-diol (HY-Y1249).
    Pentane-1,2-diol-d7
  • HY-141569
    Ganglioside GD1a

    		Toll-like Receptor (TLR) Inflammation/Immunology
    Ganglioside GD1a modulates toxic and inflammatory effects of E. coli lipopolysaccharide by preventing TLR4 translocation into lipid rafts. Ganglioside GD1a significantly reduces the effect of LPS on the decrease of cell survival and on stimulation of reactive oxygen species production .
    Ganglioside GD1a
  • HY-107327S
    Carazolol-d7

    (±)-Carazolol-d<sub>7sub>; DL-Carazolol-d<sub>7sub>; Suacron-d<sub>7sub>

    		 Isotope-Labeled Compounds Adrenergic Receptor Cardiovascular Disease
    Carazolol-d7 is the deuterium labeled Carazolol (HY-107327). Carazolol is a highly potent antagonist of β1/β2 adrenoceptor. Carazolol is also a potent, selective β3-adrenoceptor agonist. Carazolol can be used in the research of hypertension .
    Carazolol-d7
  • HY-N0006S
    Demethoxycurcumin-d7

    Curcumin II-d<sub>7sub>; Desmethoxycurcumin-d<sub>7sub>; Monodemethoxycurcumin-d<sub>7sub>

    		 Isotope-Labeled Compounds Apoptosis Autophagy Bacterial Inflammation/Immunology Cancer
    Demethoxycurcumin-d7 is the deuterium labeled Demethoxycurcumin. Demethoxycurcumin(Curcumin II), a major active curcuminoid, possess anti-inflammatory properties; also exert cytotoxic effects in human cancer cells via induction of apoptosis.
    Demethoxycurcumin-d7
  • HY-B0584S2
    Travoprost-d7

    Fluprostenol isopropyl ester-<sub>7sub>; AL6221-<sub>7sub>; Flu-Ipr-<sub>7sub>

    		 Isotope-Labeled Compounds Prostaglandin Receptor Cardiovascular Disease Endocrinology
    Travoprost-d7 (Fluprostenol isopropyl ester-d7) is deuterium labeled Travoprost. Travoprost (Fluprostenol isopropyl ester), an isopropyl ester proagent, is a high affinity, selective FP prostaglandin full receptor agonist. Travoprost has the ocular hypotensive efficacy and has the potential for glaucoma and ocular hypertension .
    Travoprost-d7
  • HY-B0389S6
    D-Glucose-d7

    Glucose-d<sub>7sub>; D-(+)-Glucose-d<sub>7sub>; Dextrose-d<sub>7sub>

    		 Isotope-Labeled Compounds Endogenous Metabolite Metabolic Disease
    D-Glucose-d77 is the deuterium labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response .
    D-Glucose-d7
  • HY-66005S2
    Acetaminophen-d7

    Paracetamol-d<sub>7sub>; 4-Acetamidophenol-d<sub>7sub>; 4'-Hydroxyacetanilide-d<sub>7sub>

    		 COX Endogenous Metabolite Histone Acetyltransferase Inflammation/Immunology
    Acetaminophen-d7 is the deuterium labeled Acetaminophen. Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM; is a widely used antipyretic and analgesic agent. Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor.
    Acetaminophen-d7
  • HY-D0711S2
    Indocyanine green-d7

    Foxgreen-d<sub>7sub>; IC Green-d<sub>7sub>; Cardiogreen-d<sub>7sub>

    		 Isotope-Labeled Compounds Fluorescent Dye Others
    Indocyanine green-d7 (Foxgreen-d7) is the deuterium labeled Indocyanine green (HY-D0711). Indocyanine green is a low toxicic fluorescent agent that has been widely used in medical diagnostics, such as determining cardiac output, hepatic function, and liver blood flow, and for ophthalmic angiography .
    Indocyanine green-d7
  • HY-107352S
    Fosfenopril-d7

    Fosinoprilat-d<sub>7sub>; Fosinoprilic acid-d<sub>7sub>; SQ 27519-d<sub>7sub>

    		 Angiotensin-converting Enzyme (ACE) Interleukin Related NF-κB TNF Receptor Toll-like Receptor (TLR) Isotope-Labeled Compounds Others
    Fosfenopril-d7 is deuterium labeled Fosfenopril.
    Fosfenopril-d7
  • HY-152000S
    C18 Ganglioside GM1-d3 ammonium

    		Isotope-Labeled Compounds Others
    C18 Ganglioside GM1-d3 (ammonium) is deuterium labeled C18 Ganglioside GM1 (ammonium) .
    C18 Ganglioside GM1-d3 ammonium
  • HY-E70043
    Ganglioside sialidase (AuSialidase S)

    Sialidase isoenzyme S; AuSialidase S

    		 Endogenous Metabolite Metabolic Disease
    Ganglioside sialidase (AuSialidase S) is an endogenous metabolite. Ganglioside sialidases have been implicated in neuronal differentiation processes, including neurite outgrowth .
    Ganglioside sialidase (AuSialidase S)
  • HY-N7101S
    Cefpodoxime proxetil-d7

    U-76-d<sub>7sub>,252-d<sub>7sub>; CS-807-d<sub>7sub>

    		 Isotope-Labeled Compounds Bacterial Antibiotic Penicillin-binding protein (PBP) Infection
    Cefpodoxime proxetil-d7 (U-76-d7,252-d7; CS-807-d7) is the deuterium labeled Cefpodoxime Proxetil (HY-N7101). Cefpodoxime Proxetil is an orally active broad spectrum third-generation cephalosporin with potent antibacterial activity against both Gram-positive and Gram-negative bacteria including staphylococci, streptococci, Haemophilus influenzae, Neisseria gonorrhoeae, Escherichia coli, Klebsiella pnuemoniae, Citrobacter spp, and Proteus spp. Cefpodoxime Proxetil binds to penicillin binding proteins (PBPs), which inhibits peptidoglycan synthesis, finally results in interfering bacterial cell wall biosynthesis. Cefpodoxime Proxetil can be used against skin structure infections, acute otitis media, pharyngitis, tonsillitis, upper respiratory tract infection, urinary tract infections and sexually transmitted diseases [3] .
    Cefpodoxime proxetil-d7
  • HY-12057S1
    Vemurafenib-d7

    PLX4032-d<sub>7sub>; RG7204-d<sub>7sub>; RO5185426-d<sub>7sub>

    		 Isotope-Labeled Compounds Raf Autophagy Cancer
    Vemurafenib-d7 is deuterium labeled Vemurafenib. Vemurafenib (PLX4032) is a first-in-class, selective, potent inhibitor of B-RAF kinase, with IC50s of 31 and 48 nM for RAFV600E and c-RAF-1, respectively . Vemurafenib induces cell autophagy .
    Vemurafenib-d7
  • HY-15149S2
    Romidepsin-d7

    FK 228-d<sub>7sub>; FR 901228-d<sub>7sub>; NSC 630176-d<sub>7sub>

    		 Isotope-Labeled Compounds HDAC Apoptosis Cancer
    Romidepsin-d7 (FK 228-d7) is deuterium labeled Romidepsin. Romidepsin (FK 228) is a Histone deacetylase (HDAC) inhibitor with anti-tumor activities. Romidepsin (FK 228) inhibits HDAC1, HDAC2, HDAC4, and HDAC6 with IC50s of 36 nM, 47 nM, 510 nM and 1.4 μM, respectively . Romidepsin (FK 228) is produced by Chromobacterium violaceum, induces cell G2/M phase arrest and apoptosis .
    Romidepsin-d7
  • HY-B1548S
    Benznidazole-d7

    Benznidazol-d<sub>7sub>; Ro 07-1051-d<sub>7sub>; Ro 71051-d<sub>7sub>

    		 Isotope-Labeled Compounds Parasite Antibiotic Infection
    Benznidazole-d7 (Benznidazol-d7; Ro 07-1051-d7; Ro 71051-d7) is the deuterium labeled Benznidazole (HY-B1548). Benznidazole (Ro 07-1051) is an antiparasitic medication, with an IC50 of 20.35 μM for Colombian T. cruzi strains, and has been used in the treatment of Chagas disease .
    Benznidazole-d7
  • HY-15027S4
    5-Aminosalicylic acid-d7

    5-ASA-d<sub>7sub>; Mesalamie-d<sub>7sub>; Mesalazie-d<sub>7sub>

    		 Isotope-Labeled Compounds PPAR PAK Endogenous Metabolite NF-κB Inflammation/Immunology Cancer
    5-Aminosalicylic acid-d7 (5-ASA-d7; Mesalamie-d7; Mesalazie-d7) is deuterium labeled 5-Aminosalicylic Acid. 5-Aminosalicylic acid (Mesalamine) acts as a specific PPARγ agonist and also inhibits p21-activated kinase 1 (PAK1) and NF-κB. 5-Aminosalicylic acid can inhibit the activity of osteopontin (OPN) .
    5-Aminosalicylic acid-d7
  • HY-W653985
    Cortodoxone-d7

    11-Deoxycortisol-d<sub>7sub>; Cortexolone-d<sub>7sub>; Reichstein's substance S-d<sub>7sub>

    		 Isotope-Labeled Compounds Glucocorticoid Receptor Endogenous Metabolite Inflammation/Immunology Endocrinology
    Cortodoxone-d7 (11-Deoxycortisol-d7) is a deuterium labeled Cortodoxone (HY-77839). Cortodoxone (11-Deoxycortisol; cortexolone) is a glucocorticoid steroid hormone and also is a glucocorticoid antagonist. Cortodoxone increases tryptophan oxygenase (TO) activity and induces the secretion of corticosterone. Cortodoxone regulates T cell proliferation and activation .
    Cortodoxone-d7
  • HY-Y1309S1
    1-Naphthol-d7

    Furro ER-d<sub>7sub>; NSC 9586-d<sub>7sub>; Nako TRB-d<sub>7sub>

    		 Isotope-Labeled Compounds Others
    1-Naphthol-d7 is the deuterium labeled Naphthol .
    1-Naphthol-d7
  • HY-N7745S
    Glucosylsphingosine-d7

    Glucopsychosine-d<sub>7sub>; Lyso-Gb1-d<sub>7sub>; Lyso-GL1-d<sub>7sub>

    		 Isotope-Labeled Compounds Others
    Glucosylsphingosine-d7 is deuterium labeled Glucosylsphingosine.
    Glucosylsphingosine-d7
  • HY-E70073
    Ganglioside sialidase (AuSialidase M2)

    Sialidase isoenzyme M2; AuSialidase M2

    		 Biochemical Assay Reagents Others
    Ganglioside sialidase (AuSialidase M2) from Arthrobacter ureafaciens. Ganglioside sialidase is a highly specific N-acetylneuraminidase. Ganglioside sialidase can hydrolyze the internal sialic acid of GM1 under optimal condition with sodium cholate .
    Ganglioside sialidase (AuSialidase M2)

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