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  5. Atigotatug (FUT8-KO)

Atigotatug (FUT8-KO)  (Synonyms: BMS-986012 (FUT8-KO))

Cat. No.: HY-P990902A
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Atigotatug (FUT8-KO) is an anti-fuc-GM1 monoclonal antibody expressed by CHO cells with the fucosyltransferase 8 gene (FUT8) knocked out, and fucose deficiency enhances the ADCC effect of the antibody. Atigotatug (HY-P990902) is a Fucosyl ganglioside GM1 (fuc-GM1)-targeting IgG1κ type humanized antibody. Atigotatug can induce immune-mediated tumor cell death, such as small cell lung cancer.

For research use only. We do not sell to patients.

Atigotatug (FUT8-KO) Chemical Structure

Atigotatug (FUT8-KO) Chemical Structure

CAS No. : 2733581-82-1

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Description

Atigotatug (FUT8-KO) is an anti-fuc-GM1 monoclonal antibody expressed by CHO cells with the fucosyltransferase 8 gene (FUT8) knocked out, and fucose deficiency enhances the ADCC effect of the antibody. Atigotatug (HY-P990902) is a Fucosyl ganglioside GM1 (fuc-GM1)-targeting IgG1κ type humanized antibody. Atigotatug can induce immune-mediated tumor cell death, such as small cell lung cancer[1].

CAS No.
SMILES

[Atigotatug (FUT8-KO)]
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Atigotatug (FUT8-KO) Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Atigotatug (FUT8-KO)2733581-82-1BMS-986012 (FUT8-KO)OthersFucosyltransferase 8 geneFUT8Fucosyl ganglioside GM1Fuc-GM1Inhibitorinhibitorinhibit

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