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20:3 Cholesteryl ester-d<sub>7</sub>

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Click Chemistry:	Labeling and Fluorescence Imaging (1) Azide (3) Alkynes (16)
Oligonucleotides:	miRNA mimics (8) miRNA agomirs (8) miRNA antagomirs (8) Nucleoside Phosphoramidites (1) MicroRNAs (32) Rat Pre-designed siRNA Sets (1) Mouse Pre-designed siRNA Sets (1) miRNA inhibitors (8) Cationic Lipids (2) Human Pre-designed siRNA Sets (1) Cholesterol (4) siRNAs (3)

4586

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

MCE Kits

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

4290

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Oligonucleotides

Targets Recommended: CETP Carboxylesterase (CES) P-glycoprotein

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-113448

*CE(20:3(8Z,11Z,14Z))* 20:3 (8Z,11Z,14Z) CE; 20:3 n-6 CE; 20:3 (8Z,11Z,14Z) Cholesterol ester	Endogenous Metabolite	Cardiovascular Disease
Cholesteryl homo-γ-linolenate is a cholesterol ester. It accumulates in the adrenal gland of rabbits fed a diet high in linolenic acid.1 Levels of cholesteryl homo-γ-linolenate are decreased and positively correlate with cognitive decline in HIV-infected humans.

HY-146781S

20:3 Cholesteryl ester-d7	Isotope-Labeled Compounds	Others
20:3 Cholesteryl ester-d₇ is deuterium labeled 20:3 Cholesteryl ester.

HY-146779S

*16:1 Cholesteryl* ester-d7**	Isotope-Labeled Compounds	Others
16:1 Cholesteryl ester-d₇ is deuterium labeled 16:1 Cholesteryl ester.

HY-146796S

*15:0 Cholesteryl* ester-d7**	Isotope-Labeled Compounds	Others
15:0 Cholesteryl ester-d₇ is deuterium labeled 15:0 Cholesteryl ester.

HY-146774S

*14:1 cholesteryl* ester-d7**	Isotope-Labeled Compounds	Others
14:1 cholesteryl ester-d₇ is deuterium labeled 14:1 cholesteryl ester.

HY-146227

DNA topoisomerase II inhibitor 1	Topoisomerase Apoptosis	Cancer
DNA topoisomerase II inhibitor 1 (compound 8ed) is a potent DNA topoisomerase II inhibitor. DNA topoisomerase II inhibitor 1 shows anti-proliferative activity. DNA topoisomerase II inhibitor 1 induces apoptosis and cell cycle arrest at sub G1 phase .

HY-RS13999

SUB1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SUB1 Human Pre-designed siRNA Set A contains three designed siRNAs for SUB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SUB1 Human Pre-designed siRNA Set A SUB1 Human Pre-designed siRNA Set A

HY-RS18793

Sub1 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Sub1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Sub1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Sub1 Mouse Pre-designed siRNA Set A Sub1 Mouse Pre-designed siRNA Set A

HY-RS25282

Sub1 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Sub1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Sub1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Sub1 Rat Pre-designed siRNA Set A Sub1 Rat Pre-designed siRNA Set A

HY-B0584S2

Travoprost-d7 Fluprostenol isopropyl ester-<sub>7sub>; AL6221-<sub>7sub>; Flu-Ipr-<sub>7sub>	Isotope-Labeled Compounds Prostaglandin Receptor	Cardiovascular Disease Endocrinology
Travoprost-d₇ (Fluprostenol isopropyl ester-d₇) is deuterium labeled Travoprost. Travoprost (Fluprostenol isopropyl ester), an isopropyl ester proagent, is a high affinity, selective FP prostaglandin full receptor agonist. Travoprost has the ocular hypotensive efficacy and has the potential for glaucoma and ocular hypertension .

HY-Y0054S

Isocyanic acid, p-tolyl ester-d7 1-Isocyanato-4-methylbenzene-d<sub>7sub>; 4-Isocyanatotoluene-d<sub>7sub>	Isotope-Labeled Compounds	Others
Isocyanic acid, p-tolyl ester-d₇ is the deuterium labeled Isocyanic acid, p-tolyl ester .

HY-W754640

Isopropyl 2-hydroxybenzoate-d7 Salicylic acid isopropyl ester-d<sub>7sub>	Isotope-Labeled Compounds	Others
Isopropyl 2-hydroxybenzoate-d₇ (Salicylic acid isopropyl ester-d₇) is deuterium labeled Isopropyl 2-hydroxybenzoate .

HY-162392

Anticancer agent 203	Others	Cancer
Anticancer agent 203 (compound 27) is an anticancer agent. Anticancer agent 203 shows cytotoxicity. Anticancer agent 203 has the potential for the research of hepatoma .

HY-P991249

NI-203	Amylin Receptor	Metabolic Disease
NI-203 is a monoclonal antibody inhibitor that targets amylin. NI-203 is promising for research of type 2 diabetes .

HY-10844S1

Pretomanid-d5 PA-824-d<sub>5sub>; (S)-PA 824-d<sub>5sub>	Antibiotic Bacterial Isotope-Labeled Compounds	Infection Cancer
Pretomanid-d₅ is deuterated labeled Pretomanid (HY-10844). Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 μg/mL.

HY-165869

Cholesteryl 11(E)-vaccenate Vaccenic acid Cholesteryl ester	Biochemical Assay Reagents	Metabolic Disease
Cholesteryl 11(E)-vaccenate (Vaccenic acid cholesteryl ester) is an ester product.

HY-P991498

CAL-203	Influenza Virus	Infection
CAL-203 is a human monoclonal antibody (mAb) targeting F, Fusion glycoprotein F0. CAL-203 can be used in respiratory tract infections research.

HY-15846A

(Rac)-CPI-203	Epigenetic Reader Domain	Cancer
(Rac)-CPI-203 is a racemate of CPI-203 (HY-15846) (BET bromodomain inhibitor)

HY-166276

Cholesteryl petroselinate Cholesteryl cis-6-octadecenoate	Biochemical Assay Reagents	Metabolic Disease
Cholesteryl petroselinate (Cholesteryl cis-6-octadecenoate) is an ester product.

HY-P2269

MAIT-203	Drug Derivative	Cancer
MAIT-203, a cyclopentyalanin-derived peptidomimetic, potently inhibits the interaction of adenomatous polyposis coli (APC) and Asef (RhoGEF4), but not APC-Sam68 or APC-striatin interactions. MAIT-203 binds APC-ARM with a K_i of 0.015 μM and a K_d of 0.036 μM. MAIT-203 significantly represses the migration and invasion of colorectal cancer cells.

HY-P10215

Ac-{Cpg}-Thr-Ala-{Ala(CO)}-Asp-{Cpg}-NH2	Parasite	Infection
Ac-{Cpg}-Thr-Ala-{Ala(CO)}-Asp-{Cpg}-NH2 (compound 40) is a potent **Plasmodium subtilisin-like protease 1 (SUB1)** inhibitor. SUB1-IN-1 shows IC₅₀ values of 12 nM and 10 nM against P. vivax and P. falciparum SUB1 (Pv- and PfSUB1), respectively .

HY-P2269A

*MAIT-203* acetate**	Drug Derivative	Cancer
MAIT-203 acetate is a cyclopentyalanin-derived peptidomimetic, potently inhibits the interaction of adenomatous polyposis coli (APC) and Asef (RhoGEF4), but not APC-Sam68 or APC-striatin interactions. MAIT-203 acetate binds APC-ARM with a K_i value of 0.015 μM and aK_d value of 0.036 μM. MAIT-203 acetate significantly represses the migration and invasion of colorectal cancer cells .

HY-107823R

Cholesteryl acetate (Standard)	Endogenous Metabolite	Others
Cholesteryl acetate (Standard) is the analytical standard of Cholesteryl acetate. This product is intended for research and analytical applications. Cholesteryl acetate (Cholesterol 3-acetate) is a cholesterol ester .

HY-131389

Cholesteryl heptadecanoate	Biochemical Assay Reagents	Others
Cholesteryl heptadecanoate is a cholesteryl ester internal standard that accurately determines the concentration of free cholesterol in cells without hydrolyzing triglycerides. Cholesteryl heptadecanoate can be used for the quantitative determination of cholesteryl esters by GC or LC mass spectrometry .

HY-W740449

Eicosapentaenoic acid ethyl ester-d5-1 EPA ethyl ester-d<sub>5sub>; Ethyl eicosapentaenoate-d<sub>5sub>; AMR101-d<sub>5sub>	Isotope-Labeled Compounds	Others
Eicosapentaenoic acid ethyl ester-d₅-1 (EPA ethyl ester-d₅) is deuterium labeled Eicosapentaenoic acid ethyl ester .

HY-W010697

Cholesteryl linoleate	Endogenous Metabolite	Metabolic Disease
Cholesteryl linoleate is shown to be the major cholesteryl ester contained in LDL and atherosclerotic lesions.

HY-124421R

*5F-203* (Standard)**	Aryl Hydrocarbon Receptor	Others
5F-203 (Standard) is the analytical standard of 5F-203. This product is intended for research and analytical applications. 5F-203 (NSC-703786) is a cytotoxic molecule that forms DNA adducts and cell cycle arrest. 5F-203 induces aryl hydrocarbon receptor (AhR) signaling and elevates expression of CYP1A1. 5F-203 also increases the levels of reactive oxygen species as well as activates JNK, ERK, and p38 .

HY-162418

Antibacterial agent 203	Bacterial Fungal	Infection
Antibacterial agent 203 (Compound 5h) has antibacterial and antifungal activity. Antibacterial agent 203 has potent antifungal activity against C. albicans, with a MIC of 3.90 μg/mL. Antibacterial agent 203 has antimicrobial activity on healthy mouse fibroblast cells (L929), with an IC₅₀ of 75.96 μM .

HY-19897

4SC-203	FLT3 VEGFR	Cancer
4SC-203 is a potent multikinase inhibitor with potential antineoplastic activity. 4SC-203 selectively FLT3/STK1, FLT3 mutated forms, and VEGFRs .

HY-W010697S

Cholesteryl linoleate-d11	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
Cholesteryl linoleate-d₁₁ is deuterium labeled Cholesteryl linoleate. Cholesteryl linoleate is shown to be the major cholesteryl ester contained in LDL and atherosclerotic lesions .

HY-P1925A

*GO-203* TFA** 2 Publications Verification	PI3K Reactive Oxygen Species (ROS) Apoptosis	Cancer
GO-203 TFA is a potent MUC1-C oncoprotein inhibitor. GO-203 TFA is an all D-amino acid peptide that consists of a poly-R transduction domain linked to a CQCRRKN motif that binds to the MUC1-C cytoplasmic tail and blocks MUC1-C homodimerization. GO-203 TFA downregulates TIGAR (TP53-induced glycolysis and apoptosis regulator) protein synthesis by inhibiting the PI3K-AKT-S6K1 pathway. GO-203 TFA induces the production of ROS and loss of mitochondrial transmembrane potential. GO-203 TFA inhibits the growth of colon cancer cells in vitro and as xenografts in nude mice .

HY-W714570

o-Tolylglyoxylic Acid Methyl Ester-d7 Methyl 2-oxo-2-(o-tolyl)acetate-d<sub>7sub>	Isotope-Labeled Compounds	Others
o-Tolylglyoxylic Acid Methyl Ester-d₇ (Methyl 2-oxo-2-(o-tolyl)acetate-d₇) is the deuterium labeled Methyl 2-oxo-2-(o-tolyl)acetate (HY-W278295).

HY-W013122

Cholesteryl n-butyrate Cholesteryl butyrate	Biochemical Assay Reagents	Cancer
Cholesteryl n-butyrate is a cholesterol ester composed of cholesterol and butyrate, two naturally occurring substances. Cholesteryl n-butyrate can be used to synthesize solid lipid nanoparticles (SLNs) with inhibitory activity on the adhesion and migration of colon cancer cells, providing a delivery system for the anticancer drug butyrate .

HY-W010800

Cholesteryl hemisuccinate	Topoisomerase DNA/RNA Synthesis Apoptosis Necroptosis	Cancer
Cholesteryl hemisuccinate is a with hepatoprotective an anticancer activity. Cholesteryl hemisuccinate inhibits Acetaminophen (AAP, HY-66005) hepatotoxicity, and prevents AAP-induced hepatic apoptosis and necrosis. Cholesteryl hemisuccinate inhibits DNA polymerase and DNA topoisomerase to inhibit DNA replication and repair and cell division. Thus, Cholesteryl hemisuccinate inhibits tumor growth .

HY-146959

K203	Cholinesterase (ChE)	Neurological Disease
K203 is a potent reactivator of tabun-inhibited AChE. K203 is a crucial antidote used for the organophosphate intoxication .

HY-119367

ODM-203	FGFR VEGFR	Cancer
ODM-203 is an orally active and selective FGFR/VEGFR inhibitor with IC₅₀ values of 6, 11, 16, 5, 9, 26 and 35 nM for FGFR3/1/2 and VEGFR3/2/1/4, respectively. ODM-203 has strong anti-tumour activity and activates immune responses in the tumour microenvironment .

HY-P1925B

*L-GO-203* TFA**	Mucin	Cancer
L-GO-203 TFA is a potent MUC1-C oncoprotein inhibitor. L-GO-203 TFA is an anti-cancer peptide for targeting intracellular proteins .

HY-133962

Cholesteryl erucate	Biochemical Assay Reagents	Others
Cholesteryl erucate is a cholesterol ester. It has been used as a standard for the quantification of cholesteryl esters in human meibomian gland secretions.

HY-W010800R

Cholesteryl hemisuccinate (Standard)	Reference Standards Topoisomerase DNA/RNA Synthesis Apoptosis Necroptosis	Cancer
Cholesteryl hemisuccinate (Standard) is the analytical standard of Cholesteryl hemisuccinate. This product is intended for research and analytical applications. Cholesteryl hemisuccinate is a with hepatoprotective an anticancer activity. Cholesteryl hemisuccinate inhibits Acetaminophen (AAP, HY-66005) hepatotoxicity, and prevents AAP-induced hepatic apoptosis and necrosis. Cholesteryl hemisuccinate inhibits DNA polymerase and DNA topoisomerase to inhibit DNA replication and repair and cell division. Thus, Cholesteryl hemisuccinate inhibits tumor growth[1][2].

HY-W010697R

Cholesteryl linoleate (Standard)	Endogenous Metabolite	Metabolic Disease
Cholesteryl linoleate is shown to be the major cholesteryl ester contained in LDL and atherosclerotic lesions.

HY-113369S

Cholesteryl arachidonate-d8	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
Cholesteryl arachidonate-d₈ is deuterium labeled Cholesteryl arachidonate. Cholesteryl arachidonate is an endogenous metabolite .

HY-W010708R

Cholesteryl palmitate (Standard)	Reference Standards Endogenous Metabolite	Inflammation/Immunology
Cholesteryl palmitate (Standard) is the analytical standard of Cholesteryl palmitate. This product is intended for research and analytical applications. Cholesteryl palmitate is a useful prognostic biomarker for chronic interstitial pneumonia (CIP).

HY-W009001

Cholesteryl chloride	Biochemical Assay Reagents Drug Derivative	Others
Cholesteryl chloride is an organochloride derivative of Cholesterol (HY-N0322). Cholesteryl chloride can be used in some hair colors, make-ups, and some other cosmetic preparations .

HY-W010708S

Cholesteryl palmitate-d9	Endogenous Metabolite	Inflammation/Immunology
Cholesteryl palmitate-d₉ is the deuterium labeled Cholesteryl palmitate. Cholesteryl palmitate is a useful prognostic biomarker for chronic interstitial pneumonia (CIP).

HY-W010708S1

Cholesteryl palmitate-d7	Isotope-Labeled Compounds Endogenous Metabolite	Inflammation/Immunology
Cholesteryl palmitate-d₇ is deuterium labeled Cholesteryl palmitate. Cholesteryl palmitate is a useful prognostic biomarker for chronic interstitial pneumonia (CIP) .

HY-W719338

Pentane-1,2-diol-d7 (±)-Pentane-1,2-diol<sub>7sub>; 1,2-Dihydroxypentane<sub>7sub>; 1,2-Pentylene glycol<sub>7sub>; Diol PD<sub>7sub>; Hydrolite 5<sub>7sub>; NSC 513<sub>7sub>; 1,2-Pentanediol<sub>7sub>	Isotope-Labeled Compounds	Others
Pentane-1,2-diol-d₇ ((±)-Pentane-1,2-diol-d₇; 1,2-Dihydroxypentane-d₇; 1,2-Pentylene glycol-d₇; Diol PD-d₇; Hydrolite 5-d₇; NSC 513-d₇; 1,2-Pentanediol-d₇) is the deuterium labeled Pentane-1,2-diol (HY-Y1249).

HY-W010708S2

Cholesteryl palmitate-d31	Isotope-Labeled Compounds Endogenous Metabolite	Inflammation/Immunology
Cholesteryl palmitate-d₃1 is deuterium labeled Cholesteryl palmitate. Cholesteryl palmitate is a useful prognostic biomarker for chronic interstitial pneumonia (CIP) .

HY-113217F

*BODIPY 480/508-cholesteryl* oleate**	Fluorescent Dye Liposome	Metabolic Disease
BODIPY 480/508-cholesteryl oleate is a fluorescently tagged derivative of Cholesteryl oleate (HY-113217). BODIPY 480/508-cholesteryl oleate can be used to monitor lipid transport mechanisms in mammalian cells (Ex/Em = 480/508 nm) .

HY-15846

CPI-203 4 Publications Verification	Epigenetic Reader Domain Apoptosis	Cancer
CPI-203 is a novel potent, selective and cell permeable inhibitor of BET bromodomain, with an IC₅₀ value of appr 37 nM (BRD4 α-screen assay).

HY-166289

Cholesteryl myristoleate	Biochemical Assay Reagents	Metabolic Disease
Cholesteryl myristoleate is an ester product.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W010697

Cholesteryl linoleate	Structural Classification Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite
Cholesteryl linoleate is shown to be the major cholesteryl ester contained in LDL and atherosclerotic lesions.

HY-125910

Cholesteryl Linolenate	Structural Classification Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite
Cholesteryl Linolenate is an endogenous metabolite.

HY-113369

Cholesteryl arachidonate	Structural Classification Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite
Cholesteryl arachidonate is an endogenous metabolite.

HY-111355B

Cholesteryl sulfate sodium	Structural Classification Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite
Cholesteryl sulfate sodium is an orally available, NPC2-targeted cholesterol biosynthesis agonist. Cholesteryl sulfate sodium activates SREBP2 by competitively binding to NPC2, promoting cholesterol synthesis (EC₅₀=50 μM). Cholesteryl sulfate sodium enhances the self-assembly ability of Mitoxantrone hydrochloride (HY-13502A), while repairing the intestinal mucosal barrier and inhibiting inflammation by regulating serine protease activity and PKCη signaling pathway. Cholesteryl sulfate sodium is a component of the platelet cell membrane and supports platelet adhesion. Cholesteryl sulfate sodium also regulates the activity of selective protein kinase C isoforms and modulates the specificity of PI3K, playing a role in keratinocyte differentiation .

HY-113217

Cholesteryl oleate	Structural Classification Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields Steroids	Liposome Endogenous Metabolite
Cholesteryl oleate is an ester compound formed from Cholesterol (HY-N0322) and Oleic acid (HY-N1446), which is involved in lipid transport, storage and cell membrane formation in living organisms. Cholesteryl oleate may serve as a potential biomarker for prostate cancer. Cholesteryl oleate can also prepare cationic solid lipid nanoparticles (SLNs) for efficient gene silencing .

HY-W010708

Cholesteryl palmitate	Structural Classification Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields Steroids	Endogenous Metabolite
Cholesteryl palmitate is a useful prognostic biomarker for chronic interstitial pneumonia (CIP).

HY-107823R

Cholesteryl acetate (Standard)	Structural Classification Source classification Endogenous metabolite Steroids	Endogenous Metabolite
Cholesteryl acetate (Standard) is the analytical standard of Cholesteryl acetate. This product is intended for research and analytical applications. Cholesteryl acetate (Cholesterol 3-acetate) is a cholesterol ester .

HY-W010697R

Cholesteryl linoleate (Standard)	Structural Classification Source classification Endogenous metabolite Steroids	Endogenous Metabolite
Cholesteryl linoleate is shown to be the major cholesteryl ester contained in LDL and atherosclerotic lesions.

HY-W010708R

Cholesteryl palmitate (Standard)	Structural Classification Source classification Endogenous metabolite Steroids	Reference Standards Endogenous Metabolite
Cholesteryl palmitate (Standard) is the analytical standard of Cholesteryl palmitate. This product is intended for research and analytical applications. Cholesteryl palmitate is a useful prognostic biomarker for chronic interstitial pneumonia (CIP).

HY-N15981

*15(S)-HETE Cholesteryl* ester**	Structural Classification Lipid	Biochemical Assay Reagents
15(S)-HETE Cholesteryl ester is an eicosanoid.

HY-N2339

Cholesteryl behenate 1 Publications Verification Cholesteryl docosanoate; Cholesterol behenate	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Cholesteryl behenate is a cholesterol ester associated with the neutral core of low density lipoprotein Receptor-LDL complexes are taken up by lysosomes and hydrolyzed to release cholesterol from the esters.

HY-125833

Alpha-Naphthoflavone 5+ Cited Publications	Flavonoids Flavones Source classification Indigofera heterantha Wall. ex Brand. Plants Compositae Disease Research Fields Cancer	Cytochrome P450 Aryl Hydrocarbon Receptor Apoptosis
Alpha-Naphthoflavone is an orally active flavonoid that is a potent, competitive inhibitor of aromatase< b>aromatase. < b > IC < sub > 50 < / sub > < / b > and < b > K < sub > I < / sub > < / b > value were 0.5 and 0.2 microns. Alpha-Naphthoflavone can inhibit cell proliferation and induce apoptosis .

HY-107823

Cholesteryl acetate Cholesterol 3-acetate; Cholesterin acetate; Cholesterol 3β-acetate	Structural Classification Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite
Cholesteryl acetate (Cholesterol 3-acetate) is a cholesterol ester .

HY-125833R

Alpha-Naphthoflavone (Standard)	Flavonoids Flavones Source classification Indigofera heterantha Wall. ex Brand. Plants Compositae	Cytochrome P450 Aryl Hydrocarbon Receptor Apoptosis
Alpha-Naphthoflavone (Standard) is the analytical standard of Alpha-Naphthoflavone. This product is intended for research and analytical applications. Alpha-Naphthoflavone is an orally active flavonoid that is a potent, competitive inhibitor of aromatase< b>aromatase. < b > IC < sub > 50 < / sub > < / b > and < b > K < sub > I < / sub > < / b > value were 0.5 and 0.2 microns. Alpha-Naphthoflavone can inhibit cell proliferation and induce apoptosis .

HY-N11799

Neochilenin 3-O-Methylquercetin 4′-O-glucoside	Structural Classification Flavonoids Source classification Plants Compositae Other Flavonoids	Others
Neochilenin (3-O-Methylquercetin 4 '-O-glucoside) is a glycoside of 3-O-methylquercetin, which can be isolated from the sub-family Cereoideae (Cactaceae). .

HY-W011474

Geranylgeraniol	Structural Classification Natural Products Microorganisms	NF-κB
Geranylgeraniol is an orally acitve vitamin K₂ sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model .

HY-N15356

9-Oxooctadecanedioic acid	Structural Classification Ketones, Aldehydes, Acids Source classification Plants Quercus suber L. Fagaceae	Bacterial
9-Oxooctadecanedioic acid is an α,ω-dicarboxylic fatty acid monomer found in the cork suberin of Quercus suber. It contributes to the formation of the hydrophobic barrier structure in plant cell walls and may play an important role in functions such as water resistance and protection against microbial penetration .

HY-P2274

Argifin	Infection Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields	Parasite
Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms, with IC₅₀s of 0.025 μM, 6.4 μM , 1.1 μM and 4.5 μM for SmChiA (Serratia marcescens chitinaese A), SmChiB, Aspergillus fumigatus chitinase B1 and human chitotriosidase, respectively .

HY-W011474R

Geranylgeraniol (Standard)	Structural Classification Natural Products Microorganisms	Reference Standards NF-κB
Geranylgeraniol (Standard) is the analytical standard of Geranylgeraniol. This product is intended for research and analytical applications. Geranylgeraniol is an orally acitve vitamin K2 sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model [4].

HY-N10192

Aculene D	Infection Microorganisms Classification of Application Fields Terpenoids Sesquiterpenes Source classification Disease Research Fields	Endogenous Metabolite Bacterial
Aculene D, a fungal metabolite, shows quorum sensing (QS) inhibitory activity against Chromobacterium violaceum CV026, and could significantly reduce violacein production in N-hexanoyl-l-homoserine lactone (C6-HSL) induced C. violaceum CV026 cultures at sub-inhibitory concentrations .

HY-N0662

Amentoflavone Maximum Cited Publications 12 Publications Verification Didemethyl-ginkgetin	Structural Classification Flavonoids Classification of Application Fields Source classification Phenols Polyphenols Selaginellaceae Plants Biflavones Selaginella tamariscina (P. Beauv.) Spring Disease Research Fields Cancer	Reactive Oxygen Species (ROS) Apoptosis Bacterial Fungal RSV GABA Receptor
Amentoflavone (Didemethyl-ginkgetin) is a potent and orally active GABA(A) negative modulator. Amentoflavone also shows anti-inflammatory, antioxidative, anti-viral, anti-tumor, anti-radiation, anti-fungal, antibacterial activity. Amentoflavone induces apoptosis and cell cycle arrest at sub-G1 phase .

HY-W011370

Pelargonidin chloride 1 Publications Verification	Structural Classification Anthocyans Flavonoids Classification of Application Fields Leguminosae Source classification Other Diseases Phenols Polyphenols Plants Phaseolus vulgaris Linn. Disease Research Fields	Quinone Reductase Reactive Oxygen Species (ROS)
Pelargonidin chloride is an anthocyanidin and also is a scavenger of nitric oxide radical and has antioxidant activities. Pelargonidin inhibits cell viability and induces cell cycle arrest at sub-G1 phase. Pelargonidin chloride increases the mRNA and protein expression of HO-1, NQO1, Nrf2. Pelargonidin chloride improves Aβ-induced memory and learning impairment .

HY-P2274R

Argifin (Standard)	Structural Classification Natural Products Microorganisms Source classification	Reference Standards Parasite
Argifin (Standard) is the analytical standard of Argifin. This product is intended for research and analytical applications. Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms, with IC50s of 0.025 μM, 6.4 μM , 1.1 μM and 4.5 μM for SmChiA (Serratia marcescens chitinaese A), SmChiB, Aspergillus fumigatus chitinase B1 and human chitotriosidase, respectively[1].

HY-N0662R

Amentoflavone (Standard) Didemethyl-ginkgetin (Standard)	Structural Classification Flavonoids Source classification Phenols Polyphenols Selaginellaceae Plants Biflavones Selaginella tamariscina (P. Beauv.) Spring	Reference Standards Reactive Oxygen Species (ROS) Apoptosis Bacterial Fungal RSV GABA Receptor
Amentoflavone (Standard) is the analytical standard of Amentoflavone. This product is intended for research and analytical applications. Amentoflavone (Didemethyl-ginkgetin) is a potent and orally active GABA(A) negative modulator. Amentoflavone also shows anti-inflammatory, antioxidative, anti-viral, anti-tumor, anti-radiation, anti-fungal, antibacterial activity. Amentoflavone induces apoptosis and cell cycle arrest at sub-G1 phase .

HY-N2338

Cholesterol myristate Cholesteryl myristate; Cholesteryl tetradecanoate	Structural Classification Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Steroids Cancer	nAChR GABA Receptor Potassium Channel Endogenous Metabolite
Cholesterol myristate is a natural steroid present in traditional Chinese medicine. Cholesterol myristate binds to several ion channels such as the nicotinic acetylcholine receptor, GABAA receptor, and the inward-rectifier potassium ion channel.

HY-B0504S

Creatinine-d3 5 Publications Verification NSC13123-d<sub>3sub>	Classification of Application Fields Metabolic Disease Disease Research Fields	Isotope-Labeled Compounds Endogenous Metabolite
Creatinine-d₃ is a deuterium labeled Creatinine. Creatinine is a break-down product of creatine phosphate in muscle .

HY-N8353

Stachybotramide	Structural Classification Natural Products Microorganisms Source classification	Others
Stachybotramide is a natural fungal metabolite with the property of modulating the activity of cholesteryl ester transfer protein (CETP). Stachybotramide stimulates the transfer of cholesteryl esters (CE) from high-density lipoprotein (HDL) to very-low-density lipoprotein (VLDL) and low-density lipoprotein (LDL), increasing the transfer efficiency by 1.3- to 1.5-fold. Stachybotramide slightly reduced the transfer of cholesteryl esters from LDL and VLDL to HDL at 0.5 mM. The effect of Stachybotramide on the transfer of triglycerides (TG) from HDL was not significant. By these results, Stachybotramide was shown to preferentially stimulate the CETP-mediated transfer of cholesteryl esters from HDL to VLDL and LDL .

HY-N14721

Erabulenol A	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	CETP
Erabulenol A is the inhibitor for cholesteryl ester transfer protein that can be isolated from Penicillum sp. .

HY-N9524

Ilexoside XLVIII	Aquifoliaceae Triterpenes Structural Classification Classification of Application Fields Ochrosia balansae (Guillaumin) Baill. ex Guillaumin Terpenoids Source classification Metabolic Disease Plants Disease Research Fields	Acyltransferase
Ilexoside XLVIII is an acyl CoA cholesteryl acyl transferase (ACAT) inhibitor. Ilexoside XLVIII is a triterpene saponin isolated from an aqueous extract of the leaves of Ilex kudincha .

HY-126787

17-Hydroxyventuricidin A YP-02259L-C	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields Inflammation/Immunology	Bacterial
17-Hydroxyventuricidin A (YP-02259L-C) is an antimicrobial compound.17-Hydroxyventuricidin A inhibits the growth of the two tested filamentous fungi (Verticillium dahlia and Fusarium sp.) and of Candida tropicalis R2 CIP203 .

HY-N6639

3-O-Acetyl-20-Hydroxyecdysone	Commelinaceae Classification of Application Fields Source classification Other Diseases Cyanotis arachnoidea C. B. Clarke Plants Disease Research Fields Steroids	Others
3-O-Acetyl-20-Hydroxyecdysone is an steroid isolated from the roots of Cyanotis arachnoidea C.B.Clark.

HY-B0151

Pregnenolone 5 Publications Verification 3β-Hydroxy-5-pregnen-20-one	Structural Classification Microorganisms Neurological Disease Classification of Application Fields Anti-aging Source classification Endogenous metabolite Disease Research Fields Steroids	Cannabinoid Receptor TRP Channel Endogenous Metabolite Autophagy
Pregnenolone (3β-Hydroxy-5-pregnen-20-one) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone can protect the brain from cannabis intoxication . Pregnenolone is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels .

HY-B1739

Pregnenolone monosulfate 5 Publications Verification 3β-Hydroxy-5-pregnen-20-one monosulfate	Structural Classification Source classification Endogenous metabolite Steroids	Cannabinoid Receptor TRP Channel Endogenous Metabolite Autophagy
Pregnenolone monosulfate (3β-Hydroxy-5-pregnen-20-one monosulfate) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone monosulfate acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone monosulfate can protect the brain from cannabis intoxication . Pregnenolone monosulfate is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels .

HY-110189

Pregnenolone monosulfate sodium 5 Publications Verification 3β-Hydroxy-5-pregnen-20-one monosulfate sodium	Structural Classification Source classification Endogenous metabolite Steroids	Cannabinoid Receptor TRP Channel Endogenous Metabolite Autophagy
Pregnenolone monosulfate sodium (3β-Hydroxy-5-pregnen-20-one monosulfate sodium) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone monosulfate sodium acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone monosulfate sodium can protect the brain from cannabis intoxication . Pregnenolone monosulfate sodium is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels .

HY-B0151R

Pregnenolone (Standard) 4 Publications Verification 3β-Hydroxy-5-pregnen-20-one (Standard)	Structural Classification Neurological Disease Classification of Application Fields Anti-aging Source classification Endogenous metabolite Disease Research Fields Steroids	Reference Standards Cannabinoid Receptor TRP Channel Endogenous Metabolite Autophagy
Pregnenolone (Standard) is the analytical standard of Pregnenolone. This product is intended for research and analytical applications. Pregnenolone (3β-Hydroxy-5-pregnen-20-one) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone can protect the brain from cannabis intoxication . Pregnenolone is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels .

HY-110189R

Pregnenolone monosulfate sodium (Standard)	Structural Classification Source classification Endogenous metabolite Steroids	Cannabinoid Receptor TRP Channel Endogenous Metabolite Autophagy
Pregnenolone monosulfate (sodium) (Standard) is the analytical standard of Pregnenolone monosulfate (sodium). This product is intended for research and analytical applications. Pregnenolone monosulfate sodium (3β-Hydroxy-5-pregnen-20-one monosulfate sodium) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone monosulfate sodium acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone monosulfate sodium can protect the brain from cannabis intoxication . Pregnenolone monosulfate sodium is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels .

Cat. No.	Product Name	Chemical Structure

HY-146781S

20:3 Cholesteryl ester-d7
20:3 Cholesteryl ester-d₇ is deuterium labeled 20:3 Cholesteryl ester.

HY-146779S

*16:1 Cholesteryl* ester-d7**
16:1 Cholesteryl ester-d₇ is deuterium labeled 16:1 Cholesteryl ester.

HY-146796S

*15:0 Cholesteryl* ester-d7**
15:0 Cholesteryl ester-d₇ is deuterium labeled 15:0 Cholesteryl ester.

HY-146774S

*14:1 cholesteryl* ester-d7**
14:1 cholesteryl ester-d₇ is deuterium labeled 14:1 cholesteryl ester.

HY-B0584S2

Travoprost-d7
Travoprost-d₇ (Fluprostenol isopropyl ester-d₇) is deuterium labeled Travoprost. Travoprost (Fluprostenol isopropyl ester), an isopropyl ester proagent, is a high affinity, selective FP prostaglandin full receptor agonist. Travoprost has the ocular hypotensive efficacy and has the potential for glaucoma and ocular hypertension .

HY-Y0054S

Isocyanic acid, p-tolyl ester-d7
Isocyanic acid, p-tolyl ester-d₇ is the deuterium labeled Isocyanic acid, p-tolyl ester .

HY-W754640

Isopropyl 2-hydroxybenzoate-d7
Isopropyl 2-hydroxybenzoate-d₇ (Salicylic acid isopropyl ester-d₇) is deuterium labeled Isopropyl 2-hydroxybenzoate .

HY-10844S1

Pretomanid-d5
Pretomanid-d₅ is deuterated labeled Pretomanid (HY-10844). Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 μg/mL.

HY-W740449

Eicosapentaenoic acid ethyl ester-d5-1
Eicosapentaenoic acid ethyl ester-d₅-1 (EPA ethyl ester-d₅) is deuterium labeled Eicosapentaenoic acid ethyl ester .

HY-W010697S

Cholesteryl linoleate-d11
Cholesteryl linoleate-d₁₁ is deuterium labeled Cholesteryl linoleate. Cholesteryl linoleate is shown to be the major cholesteryl ester contained in LDL and atherosclerotic lesions .

HY-W714570

o-Tolylglyoxylic Acid Methyl Ester-d7
o-Tolylglyoxylic Acid Methyl Ester-d₇ (Methyl 2-oxo-2-(o-tolyl)acetate-d₇) is the deuterium labeled Methyl 2-oxo-2-(o-tolyl)acetate (HY-W278295).

HY-113369S

Cholesteryl arachidonate-d8
Cholesteryl arachidonate-d₈ is deuterium labeled Cholesteryl arachidonate. Cholesteryl arachidonate is an endogenous metabolite .

HY-W010708S

Cholesteryl palmitate-d9
Cholesteryl palmitate-d₉ is the deuterium labeled Cholesteryl palmitate. Cholesteryl palmitate is a useful prognostic biomarker for chronic interstitial pneumonia (CIP).

HY-W010708S1

Cholesteryl palmitate-d7
Cholesteryl palmitate-d₇ is deuterium labeled Cholesteryl palmitate. Cholesteryl palmitate is a useful prognostic biomarker for chronic interstitial pneumonia (CIP) .

HY-W719338

Pentane-1,2-diol-d7
Pentane-1,2-diol-d₇ ((±)-Pentane-1,2-diol-d₇; 1,2-Dihydroxypentane-d₇; 1,2-Pentylene glycol-d₇; Diol PD-d₇; Hydrolite 5-d₇; NSC 513-d₇; 1,2-Pentanediol-d₇) is the deuterium labeled Pentane-1,2-diol (HY-Y1249).

HY-W010708S2

Cholesteryl palmitate-d31
Cholesteryl palmitate-d₃1 is deuterium labeled Cholesteryl palmitate. Cholesteryl palmitate is a useful prognostic biomarker for chronic interstitial pneumonia (CIP) .

HY-134127S2

Hexacosanoic acid methyl ester-d3
Hexacosanoic acid methyl ester-d₃ (C26:0 methyl ester-d₃) is deuterium labeled Methyl hexacosanoate. Methyl hexacosanoate is a biochemical reagent that can be used as a biological material or organic compound for life science related research .

HY-107327S

Carazolol-d7
Carazolol-d₇ is the deuterium labeled Carazolol (HY-107327). Carazolol is a highly potent antagonist of β₁/β₂ adrenoceptor. Carazolol is also a potent, selective β₃-adrenoceptor agonist. Carazolol can be used in the research of hypertension .

HY-N0006S

Demethoxycurcumin-d7
Demethoxycurcumin-d₇ is the deuterium labeled Demethoxycurcumin. Demethoxycurcumin(Curcumin II), a major active curcuminoid, possess anti-inflammatory properties; also exert cytotoxic effects in human cancer cells via induction of apoptosis.

HY-113217S

Cholesteryl oleate-d7

Cholesteryl oleate-d₇ is deuterium labeled Cholesteryl oleate. Cholesteryl oleate is an ester compound formed from Cholesterol (HY-N0322) and Oleic acid (HY-N1446), which is involved in lipid transport, storage and cell membrane formation in living organisms. Cholesteryl oleate may serve as a potential biomarker for prostate cancer. Cholesteryl oleate can also prepare cationic solid lipid nanoparticles (SLNs) for efficient gene silencing .

HY-66005S2

Acetaminophen-d7
Acetaminophen-d₇ is the deuterium labeled Acetaminophen. Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM; is a widely used antipyretic and analgesic agent. Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor.

HY-B0389S6

D-Glucose-d7
D-Glucose-d₇7 is the deuterium labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response .

HY-D0711S2

Indocyanine green-d7
Indocyanine green-d7 (Foxgreen-d7) is the deuterium labeled Indocyanine green (HY-D0711). Indocyanine green is a low toxicic fluorescent agent that has been widely used in medical diagnostics, such as determining cardiac output, hepatic function, and liver blood flow, and for ophthalmic angiography .

HY-107352S

Fosfenopril-d7
Fosfenopril-d₇ is deuterium labeled Fosfenopril.

HY-10585AS

Valproic acid-d7 sodium

Valproic acid-d₇ (sodium) is the deuterium labeled Valproic acid (sodium salt). Valproic acid sodium salt (Sodium Valproate) is an HDAC inhibitor, with IC₅₀ in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC₅₀, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid sodium salt activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid sodium salt is used in the treatment of epilepsy, bipolar disorder and prevention of migraine headaches .

HY-N7101S

Cefpodoxime proxetil-d7

Cefpodoxime proxetil-d₇ (U-76-d₇,252-d₇; CS-807-d₇) is the deuterium labeled Cefpodoxime Proxetil (HY-N7101). Cefpodoxime Proxetil is an orally active broad spectrum third-generation cephalosporin with potent antibacterial activity against both Gram-positive and Gram-negative bacteria including staphylococci, streptococci, Haemophilus influenzae, Neisseria gonorrhoeae, Escherichia coli, Klebsiella pnuemoniae, Citrobacter spp, and Proteus spp. Cefpodoxime Proxetil binds to penicillin binding proteins (PBPs), which inhibits peptidoglycan synthesis, finally results in interfering bacterial cell wall biosynthesis. Cefpodoxime Proxetil can be used against skin structure infections, acute otitis media, pharyngitis, tonsillitis, upper respiratory tract infection, urinary tract infections and sexually transmitted diseases .

HY-12057S1

Vemurafenib-d7
Vemurafenib-d₇ is deuterium labeled Vemurafenib. Vemurafenib (PLX4032) is a first-in-class, selective, potent inhibitor of B-RAF kinase, with IC₅₀s of 31 and 48 nM for RAFV600E and c-RAF-1, respectively . Vemurafenib induces cell autophagy .

HY-15149S2

Romidepsin-d7

Romidepsin-d₇ (FK 228-d₇) is deuterium labeled Romidepsin. Romidepsin (FK 228) is a Histone deacetylase (HDAC) inhibitor with anti-tumor activities. Romidepsin (FK 228) inhibits HDAC1, HDAC2, HDAC4, and HDAC6 with IC₅₀s of 36 nM, 47 nM, 510 nM and 1.4 μM, respectively . Romidepsin (FK 228) is produced by Chromobacterium violaceum, induces cell G2/M phase arrest and apoptosis .

HY-B1548S

Benznidazole-d7
Benznidazole-d₇ (Benznidazol-d₇; Ro 07-1051-d₇; Ro 71051-d₇) is the deuterium labeled Benznidazole (HY-B1548). Benznidazole (Ro 07-1051) is an antiparasitic medication, with an IC₅₀ of 20.35 μM for Colombian T. cruzi strains, and has been used in the treatment of Chagas disease .

HY-15027S4

5-Aminosalicylic acid-d7
5-Aminosalicylic acid-d₇ (5-ASA-d₇; Mesalamie-d₇; Mesalazie-d₇) is deuterium labeled 5-Aminosalicylic Acid. 5-Aminosalicylic acid (Mesalamine) acts as a specific PPARγ agonist and also inhibits p21-activated kinase 1 (PAK1) and NF-κB. 5-Aminosalicylic acid can inhibit the activity of osteopontin (OPN) .

HY-W653985

Cortodoxone-d7
Cortodoxone-d₇ (11-Deoxycortisol-d₇) is a deuterium labeled Cortodoxone (HY-77839). Cortodoxone (11-Deoxycortisol; cortexolone) is a glucocorticoid steroid hormone and also is a glucocorticoid antagonist. Cortodoxone increases tryptophan oxygenase (TO) activity and induces the secretion of corticosterone. Cortodoxone regulates T cell proliferation and activation .

HY-B0148S

Risedronic acid-d4

Risedronic acid-d₄ (Risedronate-d₄) is the deuterium labeled Risedronic acid (HY-B0148). Risedronic acid (Risedronate) is a bisphosphonate and potent antiresorptive agent. Risedronic acid induces Apoptosis. Risedronic acid inhibits the transfer of farnesyl pyrophosphate groups to parasite proteins. Risedronic acid inhibits osteoclast-mediated bone resorption and alters bone metabolism. Risedronic acid inhibits blood-stage Plasmodium falciparum (IC₅₀ of 20.3 μM) .

HY-Y1309S1

1-Naphthol-d7
1-Naphthol-d7 is the deuterium labeled Naphthol .

HY-N7745S

Glucosylsphingosine-d7
Glucosylsphingosine-d₇ is deuterium labeled Glucosylsphingosine.

HY-113217S1

Cholesteryl oleate-d7-1

Cholesteryl oleate-d₇-1 is deuterium labeled Cholesteryl oleate. Cholesteryl oleate is an ester compound formed from Cholesterol (HY-N0322) and Oleic acid (HY-N1446), which is involved in lipid transport, storage and cell membrane formation in living organisms. Cholesteryl oleate may serve as a potential biomarker for prostate cancer. Cholesteryl oleate can also prepare cationic solid lipid nanoparticles (SLNs) for efficient gene silencing .

HY-167592S

*17:0-20:3* PS-d5**
17:0-20:3 PS-d₅ (1-Heptadecanoyl-2-eicosatrienoyl-sn-glycero(d₅)-3-phospho- L-serine (sodium)) is deuterium labeled 17:0-20:3 PS .

HY-167583S

*17:0-20:3* PI-d5**
17:0-20:3 PI-d₅ (1-heptadecanoyl-2-eicosatrienoyl-sn-glycero(d₅)-3-phosphoinositol (ammonium)) is deuterium labeled 17:0-20:3 PI .

HY-41700S3

D-Alanine-d7
D-Alanine-d₇ is the deuterium labeled D-Alanine. D-Alanine is a weak GlyR (inhibitory glycine receptor) and PMBA agonist, with an EC50 of 9 mM for GlyR.

HY-W778920

5α-Cholestan-3β-ol-d7
5α-Cholestan-3β-ol-d₇ (Dihydrocholesterol-d₇; 5α-Cholestanol-d₇; NSC 18188-d₇) is the deuterium labeled 5α-Cholestan-3β-ol (HY-107819). 5α-Cholestan-3β-ol is a derivitized steroid compound.

HY-135328S

Norverapamil-d7
Norverapamil-d₇ is a deuterium labeled Norverapamil ((±)-Norverapamil). Norverapamil, an N-demethylated metabolite of Verapamil, is a L-type calcium channel blocker and a P-glycoprotein (P-gp) function inhibitor .

HY-135328AS

Norverapamil-d7 hydrochloride
Norverapamil-d₇ (hydrochloride) is a deuterium labeled Norverapamil. Norverapamil ((±)-Norverapamil), an N-demethylated metabolite of Verapamil, is a L-type calcium channel blocker and a P-glycoprotein (P-gp) function inhibitor .

HY-N2334AS

Glycochenodeoxycholic acid-d7 sodium

Glycochenodeoxycholic acid-d₇ (sodium) is the deuterium labeled Glycochenodeoxycholic acid (sodium salt). Glycochenodeoxycholic acid sodium salt (Chenodeoxycholylglycine sodium salt) is a bile acid formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. Glycochenodeoxycholic acid sodium salt (Chenodeoxycholylglycine sodium salt) induces hepatocyte apoptosis .

HY-107370S

Atomoxetine-d7

Atomoxetine-d₇ (Tomoxetine-d₇) is deuterium labeled Atomoxetine. Atomoxetine (Tomoxetine) is a selective noradrenaline reuptake inhibitor with K_i values of 5, 77 and 1451 nM for norepinephrine (NE), serotonin (5-HT) and dopamine (DA) transporters, respectively. Atomoxetine (Tomoxetine) increases of DA_EX and NE_EX in the PFC and enhances catecholaminergic neurotransmission. Atomoxetine (Tomoxetine) is a potent Na ⁺ channels (VGSCs) blocker. Atomoxetine (Tomoxetine) can be used for attention-deficit hyperactivity disorder (ADHD) research .

HY-B1438S2

Canrenone-d7
Canrenone-d₇ (Aldadiene-d₇ ) is deuterium labeled Canrenone. Canrenone (Aldadiene) is an aldosterone antagonist extensively used as a diuretic agent.

HY-17025S

Rifabutin-d7
Rifabutin-d₇ is the deuterium labeled Rifabutin. Rifabutin (Ansamycin) is a semisynthetic ansamycin antibiotic with potent antimycobacterial properties. Rifabutin inhibits DNA-dependent RNA polymerase.

HY-107855S

DL-Mevalonolactone-d7
DL-Mevalonolactone-d₇ is the deuterium labeled DL-Mevalonolactone. DL-Mevalonolactone ((±)-Mevalonolactone) is the δ-lactone form of mevalonic acid, a precursor in the mevalonate pathway. DL-Mevalonolactone (Mevalonolactone) decreases mitochondrial membrane potential (?Ψm), NAD(P)H content and the capacity to retain Ca2+ in the brain, besides inducing mitochondrial swelling .

HY-30237S

(R)-Roscovitine-d7
(R)-Roscovitine-d₇ (Seliciclib-d₇; CYC202-d₇) is deuterium-labeled (R)-Roscovitine (HY-30237) .

HY-15662S

Tulathromycin A-d7
Tulathromycin A-d₇ (Tulathromycin-d₇) is deuterium labeled Tulathromycin A. Tulathromycin A (Tulathromycin), a macrolide antibiotic, inhibits protein synthesis (IC₅₀=0.26 μM) by targeting bacterial ribosome. Tulathromycin A is used for the research of respiratory disease in cattle and swine. Immunomodulatory effects .

HY-B1674S4

(±)-Leucine-d7
(±)-Leucine-d₇ is the deuterium labeled (±)-Leucine. (±)-Leucine (DL-Leucine), an isomer of Leucine, chemosterilant and dietary additive. (±)-Leucine inhibits growth of Escherichia coli HfrH by 92.08% .

HY-B0202S3

Irbesartan-d7
Irbesartan-d₇ is deuterated labeled Irbesartan (HY-B0202). Irbesartan (SR-47436) is an orally active Ang II type 1 (AT1) receptor blocker (ARB). Irbesartan can relax the blood vessels, low blood pressure and increase the supply of blood and oxygen to the heart. Irbesartan can be used for the research of high blood pressure, heart failure, and diabetic kidney disease .

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