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Entacapone-d<sub>10</sub>

" in MedChemExpress (MCE) Product Catalog:

3840

Inhibitors & Agonists

10

Biochemical Assay Reagents

7

Peptides

1

Inhibitory Antibodies

13

Natural
Products

11

Recombinant Proteins

3754

Isotope-Labeled Compounds

4

Antibodies

17

Click Chemistry

3

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Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-14280S
    Entacapone-d10

    		COMT Neurological Disease
    Entacapone-d10 is the deuterium labeled Entacapone. Entacapone is a potent, reversible, peripherally acting and orally active catechol-O-methyltransferase (COMT) inhibitor. Entacapone inhibits COMT from rat brain, erythrocytes and liver with IC50 values of 10 nM, 20 nM, and 160 nM, respectively. Entacapone is selective for COMT over other catecholamine metabolizing enzymes, including MAO-A, MAO-B, phenolsulphotransferase M (PST-M) and PST-P (IC50s>50 μM). Entacapone can be used for the research of Parkinson's disease . Entacapone serves as a inhibitor of FTO demethylation with an IC50 of 3.5 μM, can be used for the research of metabolic disorders .
    Entacapone-d10
  • HY-139089
    (Z)-Entacapone

    		COMT Metabolic Disease
    (Z)-Entacapone is a metabolite of the catechol-O-methyltransferase (COMT) inhibitor Entacapone (HY-14280). It is also a potential impurity found in commercial preparations of Entacapone and a degradant of Entacapone formed by UV light exposure.
    (Z)-Entacapone
  • HY-103509
    NNC 05-2090 hydrochloride

    		GABA Receptor Neurological Disease
    NNC 05-2090 hydrochloride is a GABA uptake inhibitor and inhibitor of the β-GABA transporter (BGT-1) (IC50< /sub>: 10.6 μM). NNC 05-2090 hydrochloride also inhibits mGAT2 with a Ki value of 1.4 μM. NNC 05-2090 has anticonvulsant activity and can be used in the study of epilepsy and neurological diseases .
    NNC 05-2090 hydrochloride
  • HY-16562S
    Irinotecan-d10

    (+)-Irinotecan-d<sub>10sub>; CPT-11-d<sub>10sub>; VAL-413-d<sub>10sub>

    		 Topoisomerase Autophagy Cancer
    Irinotecan-d10 is a deuterium labeled Irinotecan ((+)-Irinotecan). Irinotecan ((+)-Irinotecan) is a topoisomerase I inhibitor, preventing religation of the DNA strand by binding to topoisomerase I-DNA complex .
    Irinotecan-d10
  • HY-14280R
    Entacapone (Standard)

    		COMT Neurological Disease Cancer
    Entacapone (Standard) is the analytical standard of Entacapone. This product is intended for research and analytical applications. Entacapone is a potent, reversible, peripherally acting and orally active catechol-O-methyltransferase (COMT) inhibitor. Entacapone inhibits COMT from rat brain, erythrocytes and liver with IC50 values of 10 nM, 20 nM, and 160 nM, respectively. Entacapone is selective for COMT over other catecholamine metabolizing enzymes, including MAO-A, MAO-B, phenolsulphotransferase M (PST-M) and PST-P (IC50s>50 µM). Entacapone can be used for the research of Parkinson's disease . Entacapone serves as a inhibitor of FTO demethylation with an IC50 of 3.5 μM, can be used for the research of metabolic disorders .
    Entacapone (Standard)
  • HY-B0246S
    Carbamazepine-d10

    CBZ-d<sub>10sub>; NSC 169864-d<sub>10sub>

    		 Sodium Channel Autophagy Mitophagy Neurological Disease Cancer
    Carbamazepine-d10 is the deuterium labeled Carbamazepine. Carbamazepine (CBZ), a sodium channel blocker, is an anticonvulsant agent .
    Carbamazepine-d10
  • HY-W654320
    Piperin-d10

    Bioperine-d<sub>10sub>; 1-Piperoylpiperidine-d<sub>10sub>

    		 Isotope-Labeled Compounds Endogenous Metabolite P-glycoprotein Autophagy Cancer
    Piperin-d10 is deuterium labeled Piperine. Piperine is an alkaloid, can be isolated from pepper. Piperine can inhibit the activity of P-glycoprotein and CYP3A4. Piperine inhibits HeLa cells with an IC50 of 61.94±0.054 μg/mL .
    Piperin-d10
  • HY-139089S
    (Z)-Entacapone-d10

    		Isotope-Labeled Compounds Others
    (Z)-Entacapone-d10 is the deuterium labeled (Z)-Entacapone .
    (Z)-Entacapone-d10
  • HY-120146
    NNC 05-2090

    		GABA Receptor Neurological Disease
    NNC 05-2090 is aGABA uptake inhibitor and inhibitor of the β-GABA transporter (BGT-1) (IC50 sub>: 10.6 μM). NNC 05-2090 also inhibits mGAT2 with a Ki value of 1.4 μM. NNC 05-2090 has anticonvulsant activity and can be used in the study of epilepsy and neurological diseases .
    NNC 05-2090
  • HY-Y0504S1
    Trimethylammonium chloride-d10

    Hegzadesil-d<sub>10sub>; Trimethylamine hydrochloric acid-d<sub>10sub>; Trimethylamine monohydrochloride-d<sub>10sub>

    		 Endogenous Metabolite Metabolic Disease
    Trimethylammonium chloride-d10 is the deuterium labeled Trimethylammonium chloride . Trimethylammonium chloride is an endogenous metabolite.
    Trimethylammonium chloride-d10
  • HY-N7434S1
    N-Nitrosodiethylamine-d10

    Diethylnitrosamine-d<sub>10sub>; DEN-d<sub>10sub>

    		 DNA/RNA Synthesis Cancer
    N-Nitrosodiethylamine-d10 is the deuterium labeled N-Nitrosodiethylamine . N-Nitrosodiethylamine (Diethylnitrosamine) is a potent hepatocarcinogenic dialkylnitrosoamine. N-Nitrosodiethylamine is mainly present in tobacco smoke, water, cheddar cheese, cured, fried meals and many alcoholic beverages. N-Nitrosodiethylamine is responsible for the changes in the nuclear enzymes associated with DNA repair/replication. N-Nitrosodiethylamine results in various tumors in all animal species. The main target organs are the nasal cavity, trachea, lung, esophagus and liver.
    N-Nitrosodiethylamine-d10
  • HY-13738S4
    Raloxifene-d10-1

    Keoxifene-d<sub>10sub>; LY156758(free base)-d<sub>10sub>; LY139481-d<sub>10sub>

    		 Estrogen Receptor/ERR Cancer
    Raloxifene-d10-1 is the deuterium labeled Raloxifene . Raloxifene (Keoxifene) is a benzothiophene-derived selective estrogen receptor modulator (SERM). Raloxifene has estrogen-agonistic effects on bone and lipids and estrogen-antagonistic effects on the breast and uterus. Raloxifene is used for breast cancer and osteoporosis research .
    Raloxifene-d10-1
  • HY-B1550S
    Benzoin-d10

    DL-Benzoin-d<sub>10sub>; Desyl alcohol-d<sub>10sub>; (±)-2-Hydroxy-2-phenylacetophenone-d<sub>10sub>

    		 Isotope-Labeled Compounds PI3K Cancer
    Benzoin-d10 (DL-Benzoin-d10) is the deuterium labeled Benzoin (HY-B1550). Benzoin (DL-Benzoin), a natural balsamic resin, is a PI3Kα inhibitor with anticancer effects. Benzoin inihits the growth of colon cancer cell line (HCT-116). Benzoin can be used as a food additive .
    Benzoin-d10
  • HY-125350
    Entacapone acid

    Tyrphostin AG1290

    		 c-Met/HGFR Metabolic Disease
    Entacapone acid (Tyrphostin AG1290) is a tyrosine kinase inhibitor. Entacapone acid reduces hepatic protein synthesis rate (HPS) in vivo .
    Entacapone acid
  • HY-Y0727S1
    1,5-Dibromopentane-d10

    1,5-Pentanedibromide-d<sub>10sub>; Pentamethylene bromide-d<sub>10sub>; Pentamethylene dibromide-d<sub>10sub>

    		 Isotope-Labeled Compounds Others
    1,5-Dibromopentane-d10 is the deuterium labeled 1,5-Dibromopentane .
    1,5-Dibromopentane-d10
  • HY-B1674S
    (±)-Leucine-d10

    DL-Leucine-d<sub>10sub>; (RS)-Leucine-d<sub>10sub>

    		 Endogenous Metabolite Bacterial Metabolic Disease
    (±)-Leucine-d10 is the deuterium labeled (±)-Leucine. (±)-Leucine (DL-Leucine), an isomer of Leucine, chemosterilant and dietary additive. (±)-Leucine inhibits growth of Escherichia coli HfrH by 92.08% .
    (±)-Leucine-d10
  • HY-13272S3
    Dacomitinib-d10

    PF-00299804-d<sub>10sub>; PF-299804-d<sub>10sub>

    		 Isotope-Labeled Compounds EGFR Apoptosis Cancer
    Dacomitinib-d10 is deuterium labeled Dacomitinib. Dacomitinib (PF-00299804) is a specific and irreversible inhibitor of the ERBB family of kinases with IC50s of 6 nM, 45.7 nM and 73.7 nM for EGFR, ERBB2, and ERBB4, respectively .
    Dacomitinib-d10
  • HY-B0801AS
    Fexofenadine-d10 hydrochloride

    MDL-16455-d<sub>10sub> hydrochloride; Terfenadine carboxylate-d<sub>10sub> hydrochloride

    		 Isotope-Labeled Compounds Histamine Receptor Inflammation/Immunology Endocrinology
    Fexofenadine-d10 (hydrochloride) is deuterium labeled Fexofenadine (hydrochloride). Fexofenadine hydrochloride (MDL-16455 hydrochloride), a H1R antagonist, is an anti-allergic agent used in seasonal allergic rhinitis and chronic idiopathic urticarial (person aged ≥16 years) .
    Fexofenadine-d10 hydrochloride
  • HY-13272S2
    Dacomitinib-d10 dihydrochloride

    PF-00299804-d<sub>10sub> dihydrochloride; PF-299804-d<sub>10sub> dihydrochloride

    		 Isotope-Labeled Compounds EGFR Apoptosis Cancer
    Dacomitinib-d10 dihydrochloride is the deuterium labeled Dacomitinib dihydrochloride. Dacomitinib (PF-00299804) dihydrochloride is a specific and irreversible inhibitor of the ERBB family of kinases with IC50s of 6 nM, 45.7 nM and 73.7 nM for EGFR, ERBB2, and ERBB4, respectively .
    Dacomitinib-d10 dihydrochloride
  • HY-13209S
    Ambrisentan-d10

    BSF 208075-d<sub>10sub>; LU 208075-d<sub>10sub>

    		 Isotope-Labeled Compounds Cardiovascular Disease
    Ambrisentan-d10 (BSF 208075-d10; LU 208075-d10) is the deuterium labled Ambrisentan (HY-13209). Ambrisentan is a selective ET type A receptor (ETAR) antagonist.
    Ambrisentan-d10
  • HY-Y1044S
    1,5-Dihydroxypentane-d10

    1,5-Pentamethylene glycol-d<sub>10sub>; Pentamethylene glycol-d<sub>10sub>; Pentylene glycol-d<sub>10sub>

    		 Isotope-Labeled Compounds Others
    1,5-Dihydroxypentane-d10 is the deuterium labeled 1,5-Dihydroxypentane .
    1,5-Dihydroxypentane-d10
  • HY-RS13999
    SUB1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    SUB1 Human Pre-designed siRNA Set A contains three designed siRNAs for SUB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    SUB1 Human Pre-designed siRNA Set A
    SUB1 Human Pre-designed siRNA Set A
  • HY-RS18793
    Sub1 Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Sub1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Sub1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Sub1 Mouse Pre-designed siRNA Set A
    Sub1 Mouse Pre-designed siRNA Set A
  • HY-RS25282
    Sub1 Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Sub1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Sub1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Sub1 Rat Pre-designed siRNA Set A
    Sub1 Rat Pre-designed siRNA Set A
  • HY-146227
    DNA topoisomerase II inhibitor 1

    		Topoisomerase Apoptosis Cancer
    DNA topoisomerase II inhibitor 1 (compound 8ed) is a potent DNA topoisomerase II inhibitor. DNA topoisomerase II inhibitor 1 shows anti-proliferative activity. DNA topoisomerase II inhibitor 1 induces apoptosis and cell cycle arrest at sub G1 phase .
    DNA topoisomerase II inhibitor 1
  • HY-14280A
    Entacapone sodium salt

    		COMT Neurological Disease Cancer
    Entacapone sodium salt is a potent, reversible, peripherally acting and orally active catechol-O-methyltransferase (COMT) inhibitor. Entacapone sodium salt inhibits COMT from rat brain, erythrocytes and liver with IC50 values of 10 nM, 20 nM, and 160 nM, respectively. Entacapone sodium salt is selective for COMT over other catecholamine metabolizing enzymes, including MAO-A, MAO-B, phenolsulphotransferase M (PST-M) and PST-P (IC50s>50 µM). Entacapone sodium salt can be used for the research of Parkinson's disease . Entacapone sodium salt serves as as a inhibit of FTO demethylation with an IC50 of 3.5 μM, can be used for the research of metabolic disorders .
    Entacapone sodium salt
  • HY-14280
    Entacapone
    5+ Cited Publications

    		 COMT Neurological Disease Cancer
    Entacapone is a potent, reversible, peripherally acting and orally active catechol-O-methyltransferase (COMT) inhibitor. Entacapone inhibits COMT from rat brain, erythrocytes and liver with IC50 values of 10 nM, 20 nM, and 160 nM, respectively. Entacapone is selective for COMT over other catecholamine metabolizing enzymes, including MAO-A, MAO-B, phenolsulphotransferase M (PST-M) and PST-P (IC50s>50 μM). Entacapone can be used for the research of Parkinson's disease . Entacapone serves as a inhibitor of FTO demethylation with an IC50 of 3.5 μM, can be used for the research of metabolic disorders .
    Entacapone
  • HY-B0236S1
    6-Aminocaproic acid-d10

    EACA-d<sub>10sub>; Epsilon-Amino-n-caproic Acid-d<sub>10sub>; 6-Aminohexanoic acid-d<sub>10sub>

    		 Isotope-Labeled Compounds Metabolic Disease
    6-Aminocaproic acid-d10 is the deuterium labeled 6-Aminocaproic acid. 6-Aminocaproic acid (EACA), a monoamino carboxylic acid, is a potent and orally active inhibitor of plasmin and plasminogen. 6-Aminocaproic acid is a potent antifibrinolytic agent. 6-Aminocaproic acid prevents clot lysis through the competitive binding of lysine residues on plasminogen, inhibiting plasmin formation and reducing fibrinolysis. 6-Aminocaproic acid can be used for the research of bleeding disorders .
    6-Aminocaproic acid-d10
  • HY-B0978S
    Diethyltoluamide-d10

    DEET-d<sub>10sub>; N,N-Diethyl-m-toluamide-d<sub>10sub>

    		 Parasite Infection
    Diethyltoluamide-d10 is the deuterium labeled Diethyltoluamide . Diethyltoluamide is the most common active ingredient in insect repellents. It is intended to provide protection against mosquitoes, ticks, fleas, chiggers, leeches, and many other biting insects .
    Diethyltoluamide-d10
  • HY-14794AS
    Levomilnacipran-d10 hydrochloride

    (1S,2R)-Milnacipran-d<sub>10sub> hydrochloride; F2695-d<sub>10sub> hydrochloride

    		 Isotope-Labeled Compounds Serotonin Transporter Trk Receptor PI3K mTOR P-glycoprotein Akt Neurological Disease Inflammation/Immunology
    Levomilnacipran-d10 ((1S,2R)-Milnacipran-d10) hydrochloride is deuterium labeled Levomilnacipran hydrochloride (HY-B0168B). Levomilnacipran ((1S,2R)-Milnacipran) hydrochloride is the enantiomer of Milnacipran (HY-B0168) and a strong substrate of P-gp that can cross the blood-brain barrier. Levomilnacipran hydrochloride is a serotonin and norepinephrine reuptake inhibitor, with IC50 values of 10.5 nM and 19.0 nM, and Ki values of 92.2 nM and 1.2 nM for human norepinephrine transporter (NET) and serotonin transporter (SERT), respectively. Levomilnacipran hydrochloride has antidepressant and anxiolytic activities. Levomilnacipran hydrochloride can be used for the research of depression .
    Levomilnacipran-d10 hydrochloride
  • HY-B0134S1
    Bestatin-d10

    Ubenimex-d<sub>10sub>

    		 Isotope-Labeled Compounds Bacterial Antibiotic Aminopeptidase Infection Cancer
    Bestatin-d10 (Ubenimex-d10) is deuterium labeled Bestatin. Bestatin is a natural, broad-spectrum, and competitive CD13 (Aminopeptidase N)/APN and leukotriene A4 hydrolase inhibitor. Bestatin has anticancer effects .
    Bestatin-d10
  • HY-B0535S1
    Ethambutol-d10

    Emb-d<sub>10sub>

    		 Bacterial Antibiotic Infection
    Ethambutol-d10 is the deuterium labeled Ethambutol. Ethambutol is a bacteriostatic antimycobacterial agent, which obstructs the formation of cell wall by inhibiting arabinosyl transferases.
    Ethambutol-d10
  • HY-Y1067S
    Dibenzylamine-d10

    Bisbenzylamine-d<sub>10sub>

    		 Isotope-Labeled Compounds Others
    Dibenzylamine-d10 (Bisbenzylamine-d10) is the deuterium labeled Dibenzylamine .
    Dibenzylamine-d10
  • HY-B1322AS1
    Amodiaquine-d10 hydrochloride

    Amodiaquin-d<sub>10sub>

    		 Nuclear Hormone Receptor 4A/NR4A Parasite Histone Methyltransferase Isotope-Labeled Compounds Infection Neurological Disease Inflammation/Immunology
    Amodiaquine-d10 hydrochloride is deuterated labeled Amodiaquine (HY-B1322A). Amodiaquine (Amodiaquin), a 4-aminoquinoline class of antimalarial agent, is a potent and orally active histamine N-methyltransferase inhibitor. Amodiaquine is also a Nurr1 agonist and specifically binds to Nurr1-LBD (ligand binding domain) with an EC50 of ~20 μM. Anti-inflammatory effect .
    Amodiaquine-d10 hydrochloride
  • HY-12199S
    Pitolisant-d10

    Tiprolisant-d<sub>10sub>

    		 Isotope-Labeled Compounds Histamine Receptor Neurological Disease Endocrinology
    Pitolisant-d10 (Tiprolisant-d10) is deuterium labeled Pitolisant. Pitolisant is a potent and selective nonimidazole inverse agonist at the recombinant human histamine H3 receptor (Ki=0.16 nM) .
    Pitolisant-d10
  • HY-B1637S
    Ditiocarb-d10 sodium

    Sodium diethyldithiocarbamate-d<sub>10sub> sodium

    		 Isotope-Labeled Compounds HIV Biochemical Assay Reagents Infection Inflammation/Immunology Cancer
    Ditiocarb-d10 sodium (Sodium diethyldithiocarbamate-d10) is the deuterium labeled Ditiocarb sodium (HY-B1637). Ditiocarb sodium (Sodium diethyldithiocarbamate) is an orally active copper reagent. Ditiocarb sodium exhibits activities such as antioxidation, chelation, anti-tumor effects, immunomodulation, and anti-HIV properties. Ditiocarb sodium can be used in the research of tumors, inflammatory, and immune-related diseases .
    Ditiocarb-d10 sodium
  • HY-N0411S4
    β-Carotene-13C10

    Provitamin A-<sub>13<sub>C<sub>10<sub>; beta-Carotene-<sub>13<sub>C<sub>10<sub>

    		 Isotope-Labeled Compounds Endogenous Metabolite Apoptosis Reactive Oxygen Species Metabolic Disease Cancer
    β-Carotene- 13C10 (Provitamin A- 13C10) is the 13C-labeled β-Carotene (HY-N0411). β-Carotene (Provitamin A), a carotenoid compound, is a naturally-occurring vitamin A precursor. β-Carotene is a modulator of reactive oxygen species (ROS), with antioxidant and antiinflammatory activities. β-Carotene may serve as an antioxidant or as a prooxidant, depending on its intrinsic properties as well as on the redox potential of the biological environment in which it acts. β-Carotene induces breast cancer cells apoptosis, with anticancer activities .
    β-Carotene-13C10
  • HY-N1150S11
    Thymidine-13C10

    DThyd-13C<sub>10sub>; NSC 21548-13C<sub>10sub>

    		 Isotope-Labeled Compounds DNA/RNA Synthesis Endogenous Metabolite Orthopoxvirus Cancer
    Thymidine- 13C10 (DThyd- 13C10; NSC 21548- 13C10) is 13C-labeled Thymidine (HY-N1150). Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication.
    Thymidine-13C10
  • HY-N0097S4
    Guanosine-13C10

    DL-Guanosine-13C<sub>10sub>; Vernine-13C<sub>10sub>

    		 Isotope-Labeled Compounds Endogenous Metabolite HSV Infection
    Guanosine- 13C10 is the 13C labeled Guanosine (HY-N0097). Guanosine is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. Guanosine possesses anti-HSV activity .
    Guanosine-13C10
  • HY-15453S
    Devimistat-d10

    CPI-613-d<sub>10sub>

    		 Isotope-Labeled Compounds Cancer
    Devimistat-d10 (CPI-613-d10) is the deuterium-labeled Devimistat (HY-15453) .
    Devimistat-d10
  • HY-B0114S3
    Oxcarbazepine-d10

    GP 47680-d<sub>10sub>

    		 Isotope-Labeled Compounds Apoptosis Sodium Channel Neurological Disease Cancer
    Oxcarbazepine-d10 (GP 47680-d10) is deuterium labeled Oxcarbazepine. Oxcarbazepine is a sodium channel blocker . Oxcarbazepine significantly inhibits glioblastoma cell growth and induces apoptosis or G2/M arrest in glioblastoma cell lines . Anti-cancer and anticonvulsant effects .
    Oxcarbazepine-d10
  • HY-19652S1
    (S)-Oxybutynin-d10

    Esoxybutynin-d<sub>10sub>

    		 Isotope-Labeled Compounds Others
    (S)-Oxybutynin-d10 (Esoxybutynin-d10) is deuterium labeled (S)-Oxybutynin (Esoxybutyni) .
    (S)-Oxybutynin-d10
  • HY-W008151S
    Diphenyl Phosphate-d10

    DPhP-d<sub>10sub>

    		 Isotope-Labeled Compounds Metabolic Disease
    Diphenyl Phosphate-d10 (DPhP-d10) is the deuterium labled Diphenyl Phosphate (HY-W008151). Diphenyl Phosphate inhibits growth and energy metabolism of zebrafish in a sex-specific manner.
    Diphenyl Phosphate-d10
  • HY-13673S
    Goserelin-d10

    ICI 118630-d<sub>10sub>

    		 Isotope-Labeled Compounds Endocrinology Cancer
    Goserelin-d10 (ICI 118630-d10) is deuterium labeled Goserelin. Goserelin (ICI 118630), a decapeptide analogue of gonadotropin-releasing hormone (GnRH/LHRH), functions as a GnRH agonist. Goserelin can be used for the research of breast cancer, epithelial ovarian cancer and prostate cancer .
    Goserelin-d10
  • HY-19822S2
    Elacestrant-d10

    RAD1901-d<sub>10sub>

    		 Estrogen Receptor/ERR Isotope-Labeled Compounds Cancer
    Elacestrant-d10 is the deuterium labeled of Elacestrant (HY-19822). Elacestrant is an orally available and selective estrogen receptor degrader (SERD) with IC50s of 48 and 870 nM for ERα and ERβ, respectively. Elacestrant also inhibits growth of ER + breast cancer cell lines in vitro and in vivo .
    Elacestrant-d10
  • HY-14136S
    Rimonabant-d10

    SR141716-d<sub>10sub>

    		 Isotope-Labeled Compounds Cannabinoid Receptor Bacterial Infection Metabolic Disease Cancer
    Rimonabant-d10 is deuterium labeled Rimonabant. Rimonabant (SR141716) is a highly potent, brain penetrated and selective central cannabinoid receptor (CB1) antagonist with a Ki of 1.8 nM. Rimonabant (SR141716) also inhibits Mycobacterial membrane protein Large 3 (MMPL3).
    Rimonabant-d10
  • HY-P0009S1
    Cetrorelix-d10

    SB-75-d<sub>10sub>

    		 Isotope-Labeled Compounds GnRH Receptor Endocrinology
    Cetrorelix-d10 (SB-75-d10) is deuterium labeled Cetrorelix. Cetrorelix is a potent gonadotrophin-releasing hormone (GnRH) antagonist. Cetrorelix inhibits the endogenous luteinizing hormone surge during ovarian stimulation. Cetrorelix reduces cyclophosphamide induced ovarian follicular destruction in mice .
    Cetrorelix-d10
  • HY-126363S
    Ditiocarb-d10

    Diethyldithiocarbamic acid-d<sub>10sub>

    		 Isotope-Labeled Compounds HIV Infection
    Ditiocarb-d10 (Diethyldithiocarbamic acid-d10) is the deuterium labeled Ditiocarb (HY-126363) . Ditiocarb (Diethyldithiocarbamic acid) is an accelerator of the rate of copper cementation. Ditiocarb (Diethyldithiocarbamic acid) reduces the incidence of HIV infection, and also enhances adjuvant immunoresearch of high risk breast cancer .
    Ditiocarb-d10
  • HY-B0196S3
    Venlafaxine-d10

    Wy 45030-d<sub>10sub>

    		 Isotope-Labeled Compounds Serotonin Transporter Neurological Disease Cancer
    Venlafaxine-d10 (Wy 45030-d10) is deuterium labeled Venlafaxine. Venlafaxine (Wy 45030) is an orally active, potent serotonin (5-HT)/norepinephrine (NE) reuptake dual inhibitor. Venlafaxine is an antidepressant .
    Venlafaxine-d10
  • HY-15917S
    DL-dithiothreitol-d10

    DTT-d<sub>10sub>

    		 Isotope-Labeled Compounds Disulfidptosis Cancer
    DL-dithiothreitol-d10 is the deuterated form of DL-dithiothreitol. DL-dithiothreitol (DTT) is a strong reductant with anti-disulfidptosis activity. When DL-dithiothreitol is oxidized, it forms a stable six-membered ring with an internal disulfide bond .
    DL-dithiothreitol-d10

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