2. Search Result
Search Result
Results for "

Roxatidine-d<sub>10</sub> hemioxalate

" in MedChemExpress (MCE) Product Catalog:

4382

Inhibitors & Agonists

2

Fluorescent Dye

10

Biochemical Assay Reagents

9

Peptides

2

MCE Kits

2

Inhibitory Antibodies

14

Natural
Products

11

Recombinant Proteins

4281

Isotope-Labeled Compounds

11

Antibodies

17

Click Chemistry

3

Oligonucleotides

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-13225B
    Rivanicline hemioxalate
    1 Publications Verification

    RJR-2403 hemioxalate; (E)-Metanicotine hemioxalate

    		 nAChR Neurological Disease
    Rivanicline (RJR-2403) hemioxalate is a neuronal nicotinic receptor agonist. Rivanicline hemioxalate is highly selective for the rat brain cortex nAChRs (Ki = 26 nM, EC50 of 732 nM) and α4β2 subtype (Ki = 26 nM, EC50 = 16 μM). Rivanicline hemioxalate can significantly restore the learning impairment and cognitive dysfunction. Rivanicline hemioxalate can be used for the study of neurodegenerative diseases (such as schizophrenia or Alzheimer's disease) .
    Rivanicline hemioxalate
  • HY-D0162
    Malachite green hemioxalate
    1 Publications Verification

    MCCK1

    		 Fungal IKK NF-κB Apoptosis Infection Cancer
    Malachite green hemioxalate (MCCK1) is a triphenylmethane dye which can be used to detect the release of phosphate in enzymatic reactions. Malachite green hemioxalate has antibacterial activity, which is attributed to inhibition of intracellular enzymes, insertion into DNA and/or interaction with cell membranes. Malachite green hemioxalate is also a potent and selective inhibitor of IKBKE, and inhibits its downstream targets such as IκBα, p65 and IRF3. Malachite green hemioxalate exhibits antitumor activity in vitro and in vivo .
    Malachite green hemioxalate
  • HY-110037
    MRS-3777 hemioxalate

    		Adenosine Receptor Neurological Disease
    MRS-3777 hemioxalate is a selective adenosine A3 receptor antagonist .
    MRS-3777 hemioxalate
  • HY-137941S
    Roxatidine-d10 hemioxalate

    		Histamine Receptor Isotope-Labeled Compounds Others
    Roxatidine-d10 (hemioxalate) is the deuterium labeled Roxatidine hemioxalate .
    Roxatidine-d10 hemioxalate
  • HY-14811A
    Beloranib hemioxalate

    ZGN-440 hemioxalate; ZGN-433 hemioxalate; CDK732 hemioxalate

    		 MetAP Metabolic Disease
    Beloranib (ZGN-440; ZGN-433) hemioxalate is a fumagillin-class methionine aminopetidase-2 (MetAP2) inhibitor. Beloranib hemioxalate decreases food intake, body weight, fat mass, and the size of adipocytes. Beloranib hemioxalate plays an important role in anti-obesity activity or obesity research .
    Beloranib hemioxalate
  • HY-172346
    N-Hydroxy MDMA hemioxalate

    N-OH MDMA hemioxalate; FLEA hemioxalate

    		 Drug Derivative Neurological Disease Metabolic Disease
    N-Hydroxy MDMA (N-OH MDMA) hemioxalate is an N-hydroxy analogue of 3,4-methylenedioxymethamphetamine (MDMA). N-Hydroxy MDMA hemioxalate can be rapidly metabolized to MDMA and MDA in rats, which are mainly excreted in urine, and can also be detected in hair .
    N-Hydroxy MDMA hemioxalate
  • HY-143918S
    4'-Hydroxy Atomoxetine-d3 hemioxalate

    		Isotope-Labeled Compounds Others
    4'-Hydroxy Atomoxetine-d3 (hemioxalate) is the deuterium labeled 4'-Hydroxy Atomoxetine hemioxalate .
    4'-Hydroxy Atomoxetine-d3 hemioxalate
  • HY-D0162R
    Malachite green hemioxalate (Standard)

    MCCK1 (Standard)

    		 Reference Standards Fungal IKK NF-κB Apoptosis Infection Cancer
    Malachite green hemioxalate (Standard) is the analytical standard of Malachite green hemioxalate (HY-D0162). This product is intended for research and analytical applications. Malachite green hemioxalate is a triphenylmethane dye which can be used to detect the release of phosphate in enzymatic reactions. Malachite green hemioxalate has antimicrobial activity, which is attributed to inhibition of intracellular enzymes, intercalation into DNA, and/or interaction with cellular membranes. Malachite green hemioxalate is also a potent and selective inhibitor of IKBKE, and inhibits its downstream targets such as IκBα, p65 and IRF3. Malachite green hemioxalate exhibits antitumor activity in vitro and in vivo.
    Malachite green hemioxalate (Standard)
  • HY-108514
    (±)-PPCC hemioxalate

    		Sigma Receptor Neurological Disease Cancer
    (±)-PPCC hemioxalate is a compound that has the ability to regulate the activity of the sigma-1 receptor. (±)-PPCC hemioxalate can selectively bind sigma-1 protein (s1), and then activate s1 receptor leading to dissociation of s1-BIP complex to regulate ER-mitochondrial calcium signaling, which plays an important role in cell bioenergy and cell survival. (±)-PPCC hemioxalate can be used to study sigma-1 receptors in cocaine addiction, forgetting, pain, depression, Alzheimer's disease, stroke, and cancer .
    (±)-PPCC hemioxalate
  • HY-B0305AR
    Roxatidine Acetate Hydrochloride (Standard)

    		Histamine Receptor Metabolic Disease Inflammation/Immunology Cancer
    Roxatidine (Acetate Hydrochloride) (Standard) is the analytical standard of Roxatidine (Acetate Hydrochloride). This product is intended for research and analytical applications. Roxatidine Acetate Hydrochloride is a potent, selective, competitive and orally active histamine H2-receptor antagonist. Roxatidine Acetate Hydrochloride has antisecretory potency against gastric acid secretion. Roxatidine Acetate Hydrochloride can also suppress inflammatory responses and can be used for gastric and duodenal ulcers research. Roxatidine Acetate Hydrochloride has antitumor activity .
    Roxatidine Acetate Hydrochloride (Standard)
  • HY-103509
    NNC 05-2090 hydrochloride

    		GABA Receptor Neurological Disease
    NNC 05-2090 hydrochloride is a GABA uptake inhibitor and inhibitor of the β-GABA transporter (BGT-1) (IC50< /sub>: 10.6 μM). NNC 05-2090 hydrochloride also inhibits mGAT2 with a Ki value of 1.4 μM. NNC 05-2090 has anticonvulsant activity and can be used in the study of epilepsy and neurological diseases .
    NNC 05-2090 hydrochloride
  • HY-120146
    NNC 05-2090

    		GABA Receptor Neurological Disease
    NNC 05-2090 is aGABA uptake inhibitor and inhibitor of the β-GABA transporter (BGT-1) (IC50 sub>: 10.6 μM). NNC 05-2090 also inhibits mGAT2 with a Ki value of 1.4 μM. NNC 05-2090 has anticonvulsant activity and can be used in the study of epilepsy and neurological diseases .
    NNC 05-2090
  • HY-W744750
    TDHL-d10

    Tergurid-d<sub>10sub>; Terguride-d<sub>10sub>; trans-Dihydrolisuride-d<sub>10sub>

    		 Isotope-Labeled Compounds Dopamine Receptor 5-HT Receptor Neurological Disease
    TDHL-d10 (Tergurid-d10; Terguride-d10; trans-Dihydrolisuride-d10) is the deuterium labeled TDHL (HY-12714). TDHL (Tergurid) is a dopamine receptor agonist with a Kd of 0.39 nM for D2 receptor and an orally available 5-HT-2 receptor antagonist.
    TDHL-d10
  • HY-N7434S1
    N-Nitrosodiethylamine-d10

    Diethylnitrosamine-d<sub>10sub>; DEN-d<sub>10sub>; DENA-d<sub>10sub>

    		 DNA/RNA Synthesis Cancer
    N-Nitrosodiethylamine-d10 is the deuterium labeled N-Nitrosodiethylamine . N-Nitrosodiethylamine (Diethylnitrosamine) is a potent hepatocarcinogenic dialkylnitrosoamine. N-Nitrosodiethylamine is mainly present in tobacco smoke, water, cheddar cheese, cured, fried meals and many alcoholic beverages. N-Nitrosodiethylamine is responsible for the changes in the nuclear enzymes associated with DNA repair/replication. N-Nitrosodiethylamine results in various tumors in all animal species. The main target organs are the nasal cavity, trachea, lung, esophagus and liver.
    N-Nitrosodiethylamine-d10
  • HY-16562S
    Irinotecan-d10

    (+)-Irinotecan-d<sub>10sub>; CPT-11-d<sub>10sub>; VAL-413-d<sub>10sub>

    		 Topoisomerase Autophagy Cancer
    Irinotecan-d10 is a deuterium labeled Irinotecan ((+)-Irinotecan). Irinotecan ((+)-Irinotecan) is a topoisomerase I inhibitor, preventing religation of the DNA strand by binding to topoisomerase I-DNA complex .
    Irinotecan-d10
  • HY-137941R
    Roxatidine (Standard)

    		Reference Standards Histamine Receptor Inflammation/Immunology
    Roxatidine (Standard) is the analytical standard of Roxatidine. This product is intended for research and analytical applications. Roxatidine is an active metabolite of Roxatidine acetate hydrochloride, is a histamine H2-receptor antagonist. Roxatidine, an anti-ulcer agent, suppresses histamine release (thus inhibiting proton secretion) and inhibits the production of VEGF-1, an important marker of inflammation and angiogenesis. Anti-allergic inflammatory effect .
    Roxatidine (Standard)
  • HY-100703S
    Pipamperone-d10 dihydrochloride

    Floropipamide-d<sub>10sub> dihydrochloride; McN-JR 3345-d<sub>10sub> dihydrochloride; R 3345-d<sub>10sub> dihydrochloride

    		 Isotope-Labeled Compounds Dopamine Receptor 5-HT Receptor Neurological Disease
    Pipamperone-d10 (Floropipamide-d10) dihydrochloride is a deuterated Pipamperone dihydrochloride (HY-100703A). Pipamperone dihydrochloride (Floropipamide dihydrochloride) is a butyrophenone derivative and high-affinity antagonist of 5-HT2A receptor (pKi=8.2) and D4 receptor (pKi=8.0). Pipamperone dihydrochloride is also a low-affinity antagonist of D2 receptor (pKi=6.7). Pipamperone dihydrochloride affects neurotransmitter functions and exerts antipsychotic activity. Pipamperone dihydrochloride is used in the research of mental disorders such as autism-related behavioral disorders and Alzheimer's disease .
    Pipamperone-d10 dihydrochloride
  • HY-B0305A
    Roxatidine Acetate Hydrochloride

    HOE 760

    		 Histamine Receptor Metabolic Disease Inflammation/Immunology Cancer
    Roxatidine Acetate Hydrochloride is a potent, selective, competitive and orally active histamine H2-receptor antagonist. Roxatidine Acetate Hydrochloride has antisecretory potency against gastric acid secretion. Roxatidine Acetate Hydrochloride can also suppress inflammatory responses and can be used for gastric and duodenal ulcers research. Roxatidine Acetate Hydrochloride has antitumor activity .
    Roxatidine Acetate Hydrochloride
  • HY-B0305
    Roxatidine acetate

    		Histamine Receptor Metabolic Disease Inflammation/Immunology Cancer
    Roxatidine acetate is a potent, selective, competitive and orally active histamine H2-receptor antagonist. Roxatidine acetate has antisecretory potency against gastric acid secretion. Roxatidine acetate can also suppress inflammatory responses and can be used for gastric and duodenal ulcers research. Roxatidine acetate has antitumor activity .
    Roxatidine acetate
  • HY-Y0504S1
    Trimethylammonium chloride-d10

    Hegzadesil-d<sub>10sub>; Trimethylamine hydrochloric acid-d<sub>10sub>; Trimethylamine monohydrochloride-d<sub>10sub>

    		 Endogenous Metabolite Metabolic Disease
    Trimethylammonium chloride-d10 is the deuterium labeled Trimethylammonium chloride . Trimethylammonium chloride is an endogenous metabolite.
    Trimethylammonium chloride-d10
  • HY-13738S4
    Raloxifene-d10-1

    Keoxifene-d<sub>10sub>; LY156758(free base)-d<sub>10sub>; LY139481-d<sub>10sub>

    		 Estrogen Receptor/ERR Cancer
    Raloxifene-d10-1 is the deuterium labeled Raloxifene . Raloxifene (Keoxifene) is a benzothiophene-derived selective estrogen receptor modulator (SERM). Raloxifene has estrogen-agonistic effects on bone and lipids and estrogen-antagonistic effects on the breast and uterus. Raloxifene is used for breast cancer and osteoporosis research .
    Raloxifene-d10-1
  • HY-B1550S
    Benzoin-d10

    DL-Benzoin-d<sub>10sub>; Desyl alcohol-d<sub>10sub>; (±)-2-Hydroxy-2-phenylacetophenone-d<sub>10sub>

    		 Isotope-Labeled Compounds PI3K Cancer
    Benzoin-d10 (DL-Benzoin-d10) is the deuterium labeled Benzoin (HY-B1550). Benzoin (DL-Benzoin), a natural balsamic resin, is a PI3Kα inhibitor with anticancer effects. Benzoin inihits the growth of colon cancer cell line (HCT-116). Benzoin can be used as a food additive .
    Benzoin-d10
  • HY-B0246S
    Carbamazepine-d10

    CBZ-d<sub>10sub>; NSC 169864-d<sub>10sub>

    		 Sodium Channel Autophagy Mitophagy Neurological Disease Cancer
    Carbamazepine-d10 is the deuterium labeled Carbamazepine. Carbamazepine (CBZ), a sodium channel blocker, is an anticonvulsant agent .
    Carbamazepine-d10
  • HY-W654320
    Piperin-d10

    Bioperine-d<sub>10sub>; 1-Piperoylpiperidine-d<sub>10sub>

    		 Isotope-Labeled Compounds Endogenous Metabolite P-glycoprotein Autophagy Cancer
    Piperin-d10 is deuterium labeled Piperine. Piperine is an alkaloid, can be isolated from pepper. Piperine can inhibit the activity of P-glycoprotein and CYP3A4. Piperine inhibits HeLa cells with an IC50 of 61.94±0.054 μg/mL .
    Piperin-d10
  • HY-W709448
    Oxaprozin-d10

    Oxaprozinum-d<sub>10sub>; Wy21743-d<sub>10sub>

    		 Isotope-Labeled Compounds Apoptosis COX Akt IKK NF-κB Inflammation/Immunology
    Oxaprozin-d10 (Oxaprozinum-d10; Wy21743-d10) is the deuterium labeled Oxaprozin (HY-B0808). Oxaprozin is an orally active and potent COX inhibitor, with IC50 values of 2.2 μM for human platelet COX-1 and and 36 μM for IL-1-stimulated human synovial cell COX-2, respectively. Oxaprozin also inhibits the activation of NF-κB. Oxaprozin induces cell apoptosis. Oxaprozin shows anti-inflammatory activity. Oxaprozin-mediated inhibition of the Akt/IKK/NF-κB pathway contributes to its anti-inflammatory properties .
    Oxaprozin-d10
  • HY-137941
    Roxatidine

    		Histamine Receptor Caspase NF-κB p38 MAPK Inflammation/Immunology
    Roxatidine is an active metabolite of Roxatidine acetate hydrochloride, is an orally active histamine H2-receptor antagonist. Roxatidine, an anti-ulcer agent, suppresses histamine release (thus inhibiting proton secretion) and inhibits the production of VEGF-1, an important marker of inflammation and angiogenesis. Anti-allergic inflammatory effect. Roxatidine is promising for research of gastric and duodenal ulcers .
    Roxatidine
  • HY-Y0727S1
    1,5-Dibromopentane-d10

    1,5-Pentanedibromide-d<sub>10sub>; Pentamethylene bromide-d<sub>10sub>; Pentamethylene dibromide-d<sub>10sub>

    		 Isotope-Labeled Compounds Others
    1,5-Dibromopentane-d10 is the deuterium labeled 1,5-Dibromopentane .
    1,5-Dibromopentane-d10
  • HY-B1674S
    (±)-Leucine-d10

    DL-Leucine-d<sub>10sub>; (RS)-Leucine-d<sub>10sub>

    		 Endogenous Metabolite Bacterial Metabolic Disease
    (±)-Leucine-d10 is the deuterium labeled (±)-Leucine. (±)-Leucine (DL-Leucine), an isomer of Leucine, chemosterilant and dietary additive. (±)-Leucine inhibits growth of Escherichia coli HfrH by 92.08% .
    (±)-Leucine-d10
  • HY-13272S3
    Dacomitinib-d10

    PF-00299804-d<sub>10sub>; PF-299804-d<sub>10sub>

    		 Isotope-Labeled Compounds EGFR Apoptosis Cancer
    Dacomitinib-d10 is deuterium labeled Dacomitinib. Dacomitinib (PF-00299804) is a specific and irreversible inhibitor of the ERBB family of kinases with IC50s of 6 nM, 45.7 nM and 73.7 nM for EGFR, ERBB2, and ERBB4, respectively .
    Dacomitinib-d10
  • HY-B0801AS
    Fexofenadine-d10 hydrochloride

    MDL-16455-d<sub>10sub> hydrochloride; Terfenadine carboxylate-d<sub>10sub> hydrochloride

    		 Isotope-Labeled Compounds Histamine Receptor Inflammation/Immunology Endocrinology
    Fexofenadine-d10 (hydrochloride) is deuterium labeled Fexofenadine (hydrochloride). Fexofenadine hydrochloride (MDL-16455 hydrochloride), a H1R antagonist, is an anti-allergic agent used in seasonal allergic rhinitis and chronic idiopathic urticarial (person aged ≥16 years) .
    Fexofenadine-d10 hydrochloride
  • HY-13272S2
    Dacomitinib-d10 dihydrochloride

    PF-00299804-d<sub>10sub> dihydrochloride; PF-299804-d<sub>10sub> dihydrochloride

    		 Isotope-Labeled Compounds EGFR Apoptosis Cancer
    Dacomitinib-d10 dihydrochloride is the deuterium labeled Dacomitinib dihydrochloride. Dacomitinib (PF-00299804) dihydrochloride is a specific and irreversible inhibitor of the ERBB family of kinases with IC50s of 6 nM, 45.7 nM and 73.7 nM for EGFR, ERBB2, and ERBB4, respectively .
    Dacomitinib-d10 dihydrochloride
  • HY-13209S
    Ambrisentan-d10

    BSF 208075-d<sub>10sub>; LU 208075-d<sub>10sub>

    		 Isotope-Labeled Compounds Cardiovascular Disease
    Ambrisentan-d10 (BSF 208075-d10; LU 208075-d10) is the deuterium labled Ambrisentan (HY-13209). Ambrisentan is a selective ET type A receptor (ETAR) antagonist.
    Ambrisentan-d10
  • HY-169223
    Roxatidine hydrochloride

    		Endogenous Metabolite Endocrinology
    Roxatidine hydrochloride is an anti-ulcer compound with the activity of inhibiting gastric acid secretion. Roxatidine hydrochloride effectively inhibits duodenal and gastric ulcers and reduces ulcer pain. Roxatidine hydrochloride has a better safety profile than other similar compounds due to the lower dose required for effective inhibition .
    Roxatidine hydrochloride
  • HY-Y1044S
    1,5-Dihydroxypentane-d10

    1,5-Pentamethylene glycol-d<sub>10sub>; Pentamethylene glycol-d<sub>10sub>; Pentylene glycol-d<sub>10sub>

    		 Isotope-Labeled Compounds Others
    1,5-Dihydroxypentane-d10 is the deuterium labeled 1,5-Dihydroxypentane .
    1,5-Dihydroxypentane-d10
  • HY-146227
    DNA topoisomerase II inhibitor 1

    		Topoisomerase Apoptosis Cancer
    DNA topoisomerase II inhibitor 1 (compound 8ed) is a potent DNA topoisomerase II inhibitor. DNA topoisomerase II inhibitor 1 shows anti-proliferative activity. DNA topoisomerase II inhibitor 1 induces apoptosis and cell cycle arrest at sub G1 phase .
    DNA topoisomerase II inhibitor 1
  • HY-RS13999
    SUB1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    SUB1 Human Pre-designed siRNA Set A contains three designed siRNAs for SUB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    SUB1 Human Pre-designed siRNA Set A
    SUB1 Human Pre-designed siRNA Set A
  • HY-RS18793
    Sub1 Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Sub1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Sub1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Sub1 Mouse Pre-designed siRNA Set A
    Sub1 Mouse Pre-designed siRNA Set A
  • HY-RS25282
    Sub1 Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Sub1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Sub1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Sub1 Rat Pre-designed siRNA Set A
    Sub1 Rat Pre-designed siRNA Set A
  • HY-W701541
    6-Aminocaproic acid-d10 hydrochloride

    EACA-d<sub>10sub> hydrochloride; Epsilon-Amino-n-caproic Acid-d<sub>10sub> hydrochloride; 6-Aminohexanoic acid-d<sub>10sub> hydrochloride

    		 Isotope-Labeled Compounds PAI-1 Drug Derivative Cancer
    6-Aminocaproic acid-d10 hydrochloride (EACA-d10 hydrochloride; Epsilon-Amino-n-caproic Acid-d10 hydrochloride; 6-Aminohexanoic acid-d10 hydrochloride) is the deuterium labeled 6-Aminocaproic acid hydrochloride (HY-B0236A). 6-Aminocaproic acid hydrochloride, a monoamino carboxylic acid, is a potent and orally active inhibitor of plasmin and plasminogen. 6-Aminocaproic acid is a potent antifibrinolytic agent. 6-Aminocaproic acid prevents clot lysis through the competitive binding of lysine residues on plasminogen, inhibiting plasmin formation and reducing fibrinolysis. 6-Aminocaproic acid can be used for the research of bleeding disorders .
    6-Aminocaproic acid-d10 hydrochloride
  • HY-B0236S1
    6-Aminocaproic acid-d10

    EACA-d<sub>10sub>; Epsilon-Amino-n-caproic Acid-d<sub>10sub>; 6-Aminohexanoic acid-d<sub>10sub>

    		 Isotope-Labeled Compounds Metabolic Disease
    6-Aminocaproic acid-d10 is the deuterium labeled 6-Aminocaproic acid. 6-Aminocaproic acid (EACA), a monoamino carboxylic acid, is a potent and orally active inhibitor of plasmin and plasminogen. 6-Aminocaproic acid is a potent antifibrinolytic agent. 6-Aminocaproic acid prevents clot lysis through the competitive binding of lysine residues on plasminogen, inhibiting plasmin formation and reducing fibrinolysis. 6-Aminocaproic acid can be used for the research of bleeding disorders .
    6-Aminocaproic acid-d10
  • HY-B0978S
    Diethyltoluamide-d10

    DEET-d<sub>10sub>; N,N-Diethyl-m-toluamide-d<sub>10sub>

    		 Parasite Infection
    Diethyltoluamide-d10 is the deuterium labeled Diethyltoluamide . Diethyltoluamide is the most common active ingredient in insect repellents. It is intended to provide protection against mosquitoes, ticks, fleas, chiggers, leeches, and many other biting insects .
    Diethyltoluamide-d10
  • HY-14794AS
    Levomilnacipran-d10 hydrochloride

    (1S,2R)-Milnacipran-d<sub>10sub> hydrochloride; F2695-d<sub>10sub> hydrochloride

    		 Isotope-Labeled Compounds Serotonin Transporter Trk Receptor PI3K mTOR P-glycoprotein Akt Neurological Disease Inflammation/Immunology
    Levomilnacipran-d10 ((1S,2R)-Milnacipran-d10) hydrochloride is deuterium labeled Levomilnacipran hydrochloride (HY-B0168B). Levomilnacipran ((1S,2R)-Milnacipran) hydrochloride is the enantiomer of Milnacipran (HY-B0168) and a strong substrate of P-gp that can cross the blood-brain barrier. Levomilnacipran hydrochloride is a serotonin and norepinephrine reuptake inhibitor, with IC50 values of 10.5 nM and 19.0 nM, and Ki values of 92.2 nM and 1.2 nM for human norepinephrine transporter (NET) and serotonin transporter (SERT), respectively. Levomilnacipran hydrochloride has antidepressant and anxiolytic activities. Levomilnacipran hydrochloride can be used for the research of depression .
    Levomilnacipran-d10 hydrochloride
  • HY-W770206
    IDO-IN-7-d10

    NLG-919 analogue-d<sub>10sub>; GDC-0919 analogue-d<sub>10sub>

    		 Isotope-Labeled Compounds Indoleamine 2,3-Dioxygenase (IDO) Cancer
    IDO-IN-7-d10 (NLG-919 analogue-d10; GDC-0919 analogue-d10) is the deuterium labeled IDO-IN-7 (HY-13983). IDO-IN-7 (NLG-919 analogue) is a a potent IDO1 inhibitor with an IC50 of 38 nM.
    IDO-IN-7-d10
  • HY-B1322AS1
    Amodiaquine-d10 hydrochloride

    Amodiaquin-d<sub>10sub>

    		 Nuclear Hormone Receptor 4A/NR4A Parasite Histone Methyltransferase Isotope-Labeled Compounds Infection Neurological Disease Inflammation/Immunology
    Amodiaquine-d10 hydrochloride is deuterated labeled Amodiaquine (HY-B1322A). Amodiaquine (Amodiaquin), a 4-aminoquinoline class of antimalarial agent, is a potent and orally active histamine N-methyltransferase inhibitor. Amodiaquine is also a Nurr1 agonist and specifically binds to Nurr1-LBD (ligand binding domain) with an EC50 of ~20 μM. Anti-inflammatory effect .
    Amodiaquine-d10 hydrochloride
  • HY-B0535S1
    Ethambutol-d10

    Emb-d<sub>10sub>

    		 Bacterial Antibiotic Infection
    Ethambutol-d10 is the deuterium labeled Ethambutol. Ethambutol is a bacteriostatic antimycobacterial agent, which obstructs the formation of cell wall by inhibiting arabinosyl transferases.
    Ethambutol-d10
  • HY-Y1067S
    Dibenzylamine-d10

    Bisbenzylamine-d<sub>10sub>

    		 Isotope-Labeled Compounds Others
    Dibenzylamine-d10 (Bisbenzylamine-d10) is the deuterium labeled Dibenzylamine .
    Dibenzylamine-d10
  • HY-B0134S1
    Bestatin-d10

    Ubenimex-d<sub>10sub>

    		 Isotope-Labeled Compounds Bacterial Antibiotic Aminopeptidase Infection Cancer
    Bestatin-d10 (Ubenimex-d10) is deuterium labeled Bestatin. Bestatin is a natural, broad-spectrum, and competitive CD13 (Aminopeptidase N)/APN and leukotriene A4 hydrolase inhibitor. Bestatin has anticancer effects .
    Bestatin-d10
  • HY-W004059S1
    Diphenylmethanol-d10

    Benzhydrol-d<sub>10sub>

    		 Isotope-Labeled Compounds Biochemical Assay Reagents Others
    Diphenylmethanol-d10 (Benzhydrol-d10) is the deuterium labeled Benzhydrol (HY-W004059). Diphenylmethanol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Diphenylmethanol-d10
  • HY-W721874
    Adrenosterone-d10

    (+)-Adrenosterone-d<sub>10sub>

    		 Isotope-Labeled Compounds Endogenous Metabolite Androgen Receptor Cancer
    Adrenosterone-d10 ((+)-Adrenosterone-d10) is the deuterium labeled Adrenosterone (HY-17462). Adrenosterone ((+)-Adrenosterone) is a competitive hydroxysteroid (11-beta) dehydrogenase 1 (HSD11β1) inhibitor. Adrenosterone is a steroid hormone with weak androgenic effect. Adrenosterone is a dietary supplement that can decrease fat and increase muscle mass. Adrenosterone acts as a suppressor of metastatic progression of human cancer cells .
    Adrenosterone-d10
  • HY-12199S
    Pitolisant-d10

    Tiprolisant-d<sub>10sub>

    		 Isotope-Labeled Compounds Histamine Receptor Neurological Disease Endocrinology
    Pitolisant-d10 (Tiprolisant-d10) is deuterium labeled Pitolisant. Pitolisant is a potent and selective nonimidazole inverse agonist at the recombinant human histamine H3 receptor (Ki=0.16 nM) .
    Pitolisant-d10

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: