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Results for "

Tumor necrosis factor

" in MedChemExpress (MCE) Product Catalog:

By Targets:	TNF Receptor (38) Adenosine Receptor (1) Adrenergic Receptor (2) Akt (4) AMPK (1) Apoptosis (14) Cathepsin (1) CD3 (1) CDK (1) COX (2) Dipeptidyl Peptidase (1) Drug Derivative (1) Drug-Linker Conjugates for ADC (1) ERK (1) Estrogen Receptor/ERR (2) Flavivirus (4) Glucocorticoid Receptor (2) GLUT (3) Glutathione Peroxidase (1) HSP (1) IFNAR (1) Interleukin Related (3) IRAK (1) Isotope-Labeled Compounds (1) Leukotriene Receptor (2) Lipoxygenase (2) MMP (3) Monoamine Oxidase (1) NF-κB (16) NO Synthase (2) p38 MAPK (3) Parasite (2) PD-1/PD-L1 (1) Phosphodiesterase (PDE) (3) PI3K (2) PKC (1) Platelet-activating Factor Receptor (PAFR) (1) Prostaglandin Receptor (1) Proteasome (1) Reactive Oxygen Species (ROS) (3) Reference Standards (5) RIP kinase (1) SARS-CoV (1) Ser/Thr Protease (4) Sirtuin (1) Tau Protein (1) Tim3 (1) Toll-like Receptor (TLR) (2) TRP Channel (1)
By Research Areas:	Cancer (42) Cardiovascular Disease (5) Endocrinology (3) Infection (7) Inflammation/Immunology (39) Metabolic Disease (3) Neurological Disease (5)
Oligonucleotides:	Antisense Oligonucleotides (2)

Inhibitors & Agonists

Screening Libraries

Peptides

MCE Kits

Inhibitory Antibodies

Natural
Products

283

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

(S)-(+)-Rolipram (+)-Rolipram; (S)-Rolipram	Phosphodiesterase (PDE) Apoptosis	Neurological Disease Inflammation/Immunology Cancer
(S)-(+)-Rolipram ((+)-Rolipram) is a cyclic AMP(cAMP)-specific phosphodiesterase 4 (PDE4) inhibitor, with an IC₅₀ of 1100 nM. (S)-(+)-Rolipram can suppresse tumor necrosis factor-alpha (TNFα) production by human mononuclear cells .

EO 1428	p38 MAPK	Inflammation/Immunology
EO 1428 is a highly specific inhibitor of p38 of the aminobenzophenone class. EO 1428 (1 μM ) markedly attenuates LPS-induced tumor necrosis factor α-converting enzyme (TACE) activity up-regulation .

TNF-α-IN-2 1 Publications Verification	TNF Receptor	Inflammation/Immunology Cancer
TNF-α-IN-2 is a potent and orally active inhibitor of tumor necrosis factor alpha (TNFα), with an IC₅₀ of 25 nM in the HTRF assay. TNF-α-IN-2 distorts the TNFα trimer upon binding, leading to aberrant signaling when the trimer binds to TNFR1. TNF-α-IN-2 can be used for the research of rheumatoid arthritis .

SZM679	RIP kinase	Inflammation/Immunology Cancer
SZM679 is a potent, orally active and selective RIPK1 inhibitor with K_d values of 8.6 nM and >5000 nM for RIPK1 and RIPK3, respectively. SZM679 reverses the tumor necrosis factor-induced systemic inflammatory response. SZM679 decreases the Tau hyperphosphorylation, neuroinflammation, and the RIPK1 phosphorylation level in the hippocampus and cortex. SZM679 can be used in research of Alzheimer's disease (AD) .

SMTIN-T140	HSP AMPK Reactive Oxygen Species (ROS)	Cancer
SMTIN-T140 (compound 6a) is a potent TRAP1 (tumor-necrosis-factor-receptor associated protein 1) inhibitor, with an IC₅₀ of 1.646 μM. SMTIN-T140 shows anticancer activity. SMTIN-T140 leads to mitochondrial dysfunction, increases mitochondrial ROS production and activates AMPK. SMTIN-T140 potently suppressed tumor growth without any noticeable in vivo toxicity in a mouse model xenografted with PC3 prostate cancer cells .

Fasentin 4 Publications Verification	GLUT TNF Receptor Apoptosis	Cardiovascular Disease Cancer
Fasentin, a potent glucose uptake inhibitor, inhibits GLUT-1/GLUT-4 transporters. Fasentin preferentially inhibits GLUT4 (IC₅₀=68 μM) over GLUT1. Fasentin is a death receptor stimuli (FAS) sensitizer and sensitizes cells to FAS-induced cell death. Fasentin is also a tumor necrosis factor (TNF) apoptosis-inducing ligand sensitizer. Fasentin blocks glucose uptake in cancer cell lines and has anti-angiogenic activity .

R-7050 Maximum Cited Publications 25 Publications Verification TNF-α Antagonist III	TNF Receptor	Cancer
R-7050 (TNF-α Antagonist III) is a tumor necrosis factor receptor (TNFR) antagonist with greater selectivity toward TNFα.

ISIS 104838 sodium	TNF Receptor	Inflammation/Immunology Cancer
ISIS 104838 sodium is an antisense oligonucleotide agent that reduces the production of tumor necrosis factor (TNF-alpha), a substance that contributes to joint pain and swelling in rheumatoid arthritis.

Fasentin (Standard)	Reference Standards GLUT TNF Receptor Apoptosis	Cardiovascular Disease Cancer
Fasentin (Standard) is the analytical standard of Fasentin. This product is intended for research and analytical applications. Fasentin, a potent glucose uptake inhibitor, inhibits GLUT-1/GLUT-4 transporters. Fasentin preferentially inhibits GLUT4 (IC50=68 μM) over GLUT1. Fasentin is a death receptor stimuli (FAS) sensitizer and sensitizes cells to FAS-induced cell death. Fasentin is also a tumor necrosis factor (TNF) apoptosis-inducing ligand sensitizer. Fasentin blocks glucose uptake in cancer cell lines and has anti-angiogenic activity .

ISIS 104838	TNF Receptor	Inflammation/Immunology
ISIS 104838 is an antisense oligonucleotide agent that reduces the production of tumor necrosis factor (TNF-alpha), a substance that contributes to joint pain and swelling in rheumatoid arthritis.

Afelimomab MAK 195F	TNF Receptor	Infection Inflammation/Immunology
Afelimomab (MAK 195F) is an anti-tumor necrosis factor F(ab')2 monoclonal antibody fragment. Afelimomab can be used for the research of sepsis .

Desacetylxanthanol	Others	Others
Desacetylxanthanol (Compound 4) is a sesquiterpenoid derived from Xanthium strumarium. Desacetylxanthanol has anti-tumor necrosis factor-associated apoptosis-inducing ligand (TRAIL) activity .

Siegeskaurolic acid	TNF Receptor NF-κB	Inflammation/Immunology
Siegeskaurolic acid is an orally active anti-inflammatory agent. Siegeskaurolic acid inhibits the productions of nitric oxide (NO), prostaglandin E(2) (PGE(2)), tumor necrosis factor-alpha (TNF-alpha) and the activationon of nuclear factor-kappaB .

CDC801	Phosphodiesterase (PDE) TNF Receptor	Cancer
CDC801 is a potent and orally active phosphodiesterase 4 (PDE4) and tumor necrosis factor-α (TNF-α) inhibitor with IC₅₀ of 1.1 μM and 2.5 μM, respectively.

Atizoram CP-80,633	Phosphodiesterase (PDE)	Inflammation/Immunology
Atizoram (CP-80,633), a cyclic nucleotide phosphodiesterase (PDE4) inhibitor, elevates plasma cyclic AMP levels and decreases tumor necrosis factor-α (TNFα) production in mice .

Afimkibart PF-06480605; RVT-3101	TNF Receptor	Inflammation/Immunology
Afimkibart (PF-06480605) is a human IgG1 monoclonal antibody targeting tumor necrosis factor-like ligand 1A (TL1A). Afimkibart can be used in the research of inflammatory bowel disease .

Natsudaidain	p38 MAPK	Others
Natsudaidain is a kind of polymethoxyflavone. Natsudaidain can be isolated from Citrus plants. Natsudaidain inhibits **tumor necrosis factor-α and cyclooxygenase-2 production n by suppressing p38 MAPK** phosphorylation on mast cells .

Cynaropicrin	MMP NF-κB TNF Receptor	Cancer
Cynaropicrin is a sesquiterpene lactone which can inhibit **tumor necrosis factor (TNF-α) release with IC₅₀*s of 8.24 and 3.18 μM for murine and human macrophage cells, respectively. Cynaropicrin also inhibits the increase of cartilage degradation factor* (MMP13) and suppresses NF-κB signaling.

Spirohypertone B	TNF Receptor	Infection Cancer
Spirohypertone B is a potent Tumor necrosis factor-α (TNF-α) inhibitor. Spirohypertone B protects L929 cells from death induced by co-incubation with TNF-α and Actinomycin D (HY-17559) .

Nesfrotamig	TNF Receptor	Cancer
Nesfrotamig is a humanized immunoglobulin (H-γ1-scFv-L-κ) dimer monoclonal antibody targeting human epidermal growth factor receptor 2 (ERBB2) and human tumor necrosis factor receptor superfamily member 9 (TNFRSF9). Nesfrotamig is promising for research of cancers, especially in ERBB2-positive related tumor diseases, such as breast cancer and gastric cancer .

Opinercept	TNF Receptor	Inflammation/Immunology
Opinercept is a recombinant fusion protein comprising an TNFRSF1B fused to a human IgG1 Fc . Opinercept is a tumor necrosis factor-alpha (TNF-alpha) inhibitor. Opinercept can be used for the research of rheumatoid arthritis (RA) .

Triphenyl phosphate	Monoamine Oxidase Reactive Oxygen Species (ROS) NF-κB Interleukin Related TNF Receptor	Neurological Disease Inflammation/Immunology
Triphenyl phosphate is an organic phosphate flame retardant. Triphenyl phosphate can disrupt placental tryptophan metabolism by activating MAOA/ROS/NFκB, leading to abnormal neurological behavior. Triphenyl phosphate promotes oxidative stress by inducing inflammatory factors like nuclear factor kappa B (NFκB), interleukin-6, and tumor necrosis factor α. Triphenyl phosphate can also cause allergic contact dermatitis .

Eftozanermin alfa 1 Publications Verification ABBV-621	Apoptosis	Cancer
Eftozanermin alfa (ABBV-621) is a second-generation tumor necrosis factor-related apoptosis-inducing ligand receptor (TRAIL-R) agonist. Eftozanermin alfa induces apoptosis in tumor cells by activation of death receptors 4/5. Eftozanermin alfa can be used for the research of multiple solid and heme malignancies .

Zigakibart BION-1301	TNF Receptor	Inflammation/Immunology Cancer
Zigakibart (BION-1301) is an IgG4-kappa, anti-TNFSF13 (tumor necrosis factor (TNF) superfamily member 13, APRIL, CD256) humanized monoclonal antibody. Zigakibart shows anti-inflammatory activity .

BMS-566394	TNF Receptor	Others Inflammation/Immunology
BMS-566394 is a potent inhibitor of tumor necrosis factor-α (TNF-α) converting enzyme (TACE) that helps reduce the production of TNF-α, thereby alleviating inflammation and immune-mediated diseases and can be used in the study of inflammatory and autoimmune diseases .

Cenzestotug	TNF Receptor	Inflammation/Immunology Cancer
Cenzestotug is a monoclonal antibody targeting human tumor necrosis factor receptor superfamily member 4 (TNFRSF4). Cenzestotug activates relevant immune cells by binding to TNFRSF4, exerting immunostimulatory and antitumor activities. Cenzestotug is promising for research of cancer immunotherapy .

Ramantamig	CD3 TNF Receptor	Cancer
Ramantamig is a humanized monoclonal antibody targeting human CD3ε, GPRC5D, and TNFRSF17 (tumor necrosis factor receptor superfamily member 17)。Ramantamig is promising for research of cancers, especially hematological malignancies such as multiple myeloma .

8-Epiloganin	Others	Inflammation/Immunology
8-Epiloganin can be isolated from Castilleja rubra and has anti-inflammatory properties. 8-Epiloganin inhibits LPS-induced release of pro-inflammatory cytokines, namely tumor necrosis factor-α and interleukin-1β .

GW-3333	TNF Receptor MMP	Inflammation/Immunology
GW-3333 is a potent and orally active TNF-alpha-converting enzyme (TACE) and matrix metalloproteinases (MMP) inhibitor. GW-3333 inhibits tumor necrosis factor-alpha (TNF-alpha) production. GW-3333 can be used in research of arthritis .

Denopamine (R)-(-)-Denopamine; TA-064	Adrenergic Receptor	Cardiovascular Disease Cancer
Denopamine ((R)-(-)-Denopamine) is an orally active, selective β1-adrenergic agonist. Denopamine prolongs survival in a murine model of congestive heart failure induced by viral myocarditis: suppression of tumor necrosis factor-α production in the heart. Cardiovascular effects .

Opamtistomig	PD-1/PD-L1 TNF Receptor	Cancer
Opamtistomig is a humanized immunoglobulin (H-γ1-scFv-L-κ) dimer monoclonal antibody targeting human programmed death ligand 1 (PD-L1), CD274 and tumor necrosis factor receptor superfamily member 9 (TNFRSF9). Opamtistomig is promising for research of various solid tumors and hematological malignancies .

BMS-986156	TNF Receptor	Cancer
BMS-986156 is a fully humanized IgG1 agonist monoclonal antibody agonist corticosteroid-induced tumor necrosis factor receptor-related protein (GITR). BMS-986156 binds to GITR and promotes activation of T effector cells and inactivates T regulatory cells. BMS-986156 is indicated for use in advanced solid tumor studies .

SH-5	Akt Apoptosis	Cancer
SH-5 is a potent AKT inhibitor. SH-5 potentiates the apoptosis induced by tumor necrosis factor. SH-5 blocks NF-kB activation induced by TNF-a, lipopolysaccharide (HY-D1056), phorbol ester (HY-18739), and cigarette smoke .

Cynaropicrin (Standard)	Reference Standards MMP NF-κB TNF Receptor	Cancer
Cynaropicrin (Standard) is the analytical standard of Cynaropicrin. This product is intended for research and analytical applications. Cynaropicrin is a sesquiterpene lactone which can inhibit tumor necrosis factor (TNF-α) release with IC₅₀s of 8.24 and 3.18 μM for murine and human macrophage cells, respectively. Cynaropicrin also inhibits the increase of cartilage degradation factor (MMP13) and suppresses NF-κB signaling.

Nafamostat	Flavivirus TNF Receptor NF-κB Apoptosis Ser/Thr Protease	Infection Cancer
Nafamostat, an anticoagulant, is a synthetic serine protease inhibitor. Nafamostat has anticancer and antivirus effect. Nafamostat induce apoptosis by up-regulating the expression of tumor necrosis factor receptor-1 (TNFR1). Nafamostat can be used in the development of the pathological thickening of the arterial wall .

Nafamostat hydrochloride	Flavivirus TNF Receptor NF-κB Apoptosis Ser/Thr Protease	Infection Cancer
Nafamostat hydrochloride, an anticoagulant, is a synthetic serine protease inhibitor. Nafamostat hydrochloride has anticancer and antivirus effect. Nafamostat hydrochloride induces apoptosis by up-regulating the expression of tumor necrosis factor receptor-1 (TNFR1). Nafamostat hydrochloride can be used in the development of the pathological thickening of the arterial wall .

NQO2-IN-1	Reactive Oxygen Species (ROS) Apoptosis	Cancer
NQO2-IN-1 (Compound 20b) is the inhibitor for quinone oxidoreductase (NQO) that inhibits NQO2 with an IC₅₀ of 95 nM. NQO2-IN-1 overcomes the resistance of NSCLC cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) by induction of ROS and apoptosis .

Remtolumab ABT-122	TNF Receptor Interleukin Related	Inflammation/Immunology
Remtolumab (ABT-122) is a dual-variable domain immunoglobulin that neutralises both tumor necrosis factor α (TNFα) and IL-17A. Remtolumab shows dual inhibition of TNFα and IL-17A. Remtolumab can be used for rheumatoid arthritis (RA) research .

Nafamostat mesylate 10+ Cited Publications FUT-175	Flavivirus TNF Receptor NF-κB Apoptosis Ser/Thr Protease	Infection Cancer
Nafamostat mesylate (FUT-175), an anticoagulant, is a synthetic serine protease inhibitor. Nafamostat mesylate has anticancer and antivirus effect. Nafamostat mesylate induce apoptosis by up-regulating the expression of tumor necrosis factor receptor-1 (TNFR1). Nafamostat mesylate can be used in the development of the pathological thickening of the arterial wall .

(R)-Ketoprofen	COX	Inflammation/Immunology
(R)-Ketoprofen is an orally active nonsteroidal anti-inflammatory drug (NSAID) with analgesic properties. (R)-Ketoprofen does not significantly amplify the increase of inflammatory cytokines (such as tumor necrosis factor (TNF) and interleukin-1 (IL-1)) induced by LPS, but it can inhibit the anti-inflammatory activity of (S)-Ketoprofen .

TRX-518	TNF Receptor	Cancer
TRX-518 is a humanized agonist antibody targeting glucocorticoid-induced tumor necrosis factor receptor (GITR). TRX-518 specifically targets GITR⁺ Tregs and CD45RA⁻Foxp3⁺ effector Tregs (eTregs) among regulatory T cells (Tregs), reducing the number of Tregs in circulation and within tumors. TRX-518 is promising for research of cancers .

Polygalasaponin F	Toll-like Receptor (TLR) PI3K Akt NF-κB	Inflammation/Immunology Cancer
Polygalasaponin F, an oleanane-type triterpenoid saponin extracted from Polygala japonica, decreases the release of the inflammatory cytokine tumor necrosis factor a (TNFa). Polygalasaponin F reduces neuroinflammatory cytokine secretion through the regulation of the TLR4-PI3K/AKT-NF-kB signaling pathway .

11-Keto-beta-boswellic acid 11-Keto-β-boswellic acid	Lipoxygenase Leukotriene Receptor NF-κB	Metabolic Disease Cancer
11-Keto-beta-boswellic acid (11-Keto-β-boswellic acid) is a pentacyclic triterpenic acid of the oleogum resin from the bark of the Boswellia serrate tree, popularly known as Indian Frankincense. 11-Keto-beta-boswellic acid has the anti-inflammatory activity is primarily due to inhibit 5-lipoxygenase (5-LOX) and subsequent leukotriene and *nuclear factor-kappa B (NF-κB)* activation and tumor necrosis factor alpha generation production .

Denopamine (Standard)	Adrenergic Receptor	Cardiovascular Disease Cancer
Denopamine (Standard) is the analytical standard of Denopamine. This product is intended for research and analytical applications. Denopamine ((R)-(-)-Denopamine) is an orally active, selective β1-adrenergic agonist. Denopamine prolongs survival in a murine model of congestive heart failure induced by viral myocarditis: suppression of tumor necrosis factor-α production in the heart. Cardiovascular effects .

Rilunermin alfa SCB-313	Drug Derivative Apoptosis	Cancer
Rilunermin alfa (SCB-313) is a recombinant fusion protein composed of the human C-propeptide of alpha1(I) collagen (Trimer-Tag) to the C-terminus of the mature human tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL; Apo2L). Rilunermin alfa has potential pro-apoptotic and antineoplastic activities .

Cudraflavone B	NF-κB TNF Receptor COX ERK p38 MAPK Sirtuin	Inflammation/Immunology
Cudraflavone B is a prenylated flavonoid with anti-inflammatory and anti-tumor properties. Cudraflavone B is also a dual inhibitor of COX-1 and COX-2. Cudraflavone B blocks the translocation of *nuclear factor* κB (NF-κB*) from the cytoplasm to the nucleus in macrophages. Thus, Cudraflavone B inhibits tumor* necrosis factor α (TNFα) gene expression and secretion. Cudraflavone B also triggers the mitochondrial apoptotic pathway, activates NF-κB, the MAPK p38, and ERK, and induced the expression of SIRT1. Thus Cudraflavone B inhibits the growth of human oral squamous cell carcinoma cells .

Cat. No.	Product Name

HY-L161

Cytokine Inhibitors Library

1,077 compounds

Cytokines are a kind of low molecular soluble proteins synthesized and secreted by immunogen, mitogen or other factors. They have functions of regulating innate and adaptive immune responses, promoting hematopoiesis, stimulating cell activation, proliferation and differentiation. The process of releasing a large number of cytokines is also called “Cytokine storm”, which can cause damage to many tissues and organs in the body. Cytokine is involved in the pathogenesis of many human diseases, including cancer, diabetes, chronic inflammatory diseases and so on. Cytokine inhibitors are a class of essential compounds that act by directly inhibiting the synthesis and release of cytokine or blocking the binding of cytokine to their receptors. Cytokine inhibitors are important compounds for the study of tumor and autoimmune diseases.

MCE designs a unique collection of 1,077 cytokine inhibitors, mainly targeting the receptor interleukin (IL), colony-stimulating factor (CSF), interferon (IFN), tumor necrosis factor (TNF), growth factor (GF) and chemokine, which is an effective tool for development and research of anti-cancer, anti-chronic inflammatory diseases and anti-autoimmune diseases compounds.

Cat. No.	Product Name	Target	Research Area

HY-P2612

WP9QY	TNF Receptor	Others
WP9QY, TNF-a Antagonist, TNF-a Antagonist is a biological active peptide. (This cyclic peptide is designed to mimic the most critical tumor necrosis factor (TNF) recognition loop on TNF receptor I. It prevents interactions of TNF with its receptor. This TNF antagonist is a useful template for the development of small molecular inhibitors to prevent both inflammatory bone destruction and systemic bone loss in rheumatoid arthritis.)

HY-P2612A

WP9QY TFA	TNF Receptor	Others Cancer
WP9QY, TNF-a Antagonist, TNF-a Antagonist is a biological active peptide. (This cyclic peptide is designed to mimic the most critical tumor necrosis factor (TNF) recognition loop on TNF receptor I. It prevents interactions of TNF with its receptor. This TNF antagonist is a useful template for the development of small molecular inhibitors to prevent both inflammatory bone destruction and systemic bone loss in rheumatoid arthritis.)

HY-P5970

DABCYL-TNF-α-EDANS (-4 to +6) (human) TACE Substrate	Peptides	Cancer
DABCYL-TNF-α-EDANS (-4 to +6) (human) is a FRET peptide substrate of tumor necrosis factor convertase (TACE) .

HY-P3385

Rilunermin alfa SCB-313	Drug Derivative Apoptosis	Cancer
Rilunermin alfa (SCB-313) is a recombinant fusion protein composed of the human C-propeptide of alpha1(I) collagen (Trimer-Tag) to the C-terminus of the mature human tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL; Apo2L). Rilunermin alfa has potential pro-apoptotic and antineoplastic activities .

Cat. No.	Product Name

HY-K2112

*HOLO Human Tumor* Necrosis Factor-α (TNF-α) Detection Kit**
MCE HOLO Human Tumor Necrosis Factor-α (TNF-α) Detection Kit is a homogeneous luminescence-based assay used for the quantitative detection of human TNF-α concentrations in biological samples such as buffer solutions, cell culture supernatants, or serum.

HY-K2114

*HOLO Mouse Tumor* Necrosis Factor-α (TNF-α) Detection Kit**
MCE HOLO Mouse Tumor Necrosis Factor-α (TNF-α) Detection Kit is a homogeneous luminescence-based assay used for the quantitative detection of mouse TNF-α concentrations in biological samples such as buffer solutions, cell culture supernatants, or serum.

HY-K2113

*HOLO Human Tumor* Necrosis Factor-β (TNF-β) Detection Kit**
MCE HOLO Human Tumor Necrosis Factor-β (TNF-β) Detection Kit is a homogeneous luminescence-based assay used for the quantitative detection of human TNF-β concentrations in biological samples such as buffer solutions, cell culture supernatants, or serum.

Cat. No.	Product Name	Target	Research Area

HY-P99425

Afelimomab MAK 195F	TNF Receptor	Infection Inflammation/Immunology
Afelimomab (MAK 195F) is an anti-tumor necrosis factor F(ab')2 monoclonal antibody fragment. Afelimomab can be used for the research of sepsis .

HY-P990876

Afimkibart PF-06480605; RVT-3101	TNF Receptor	Inflammation/Immunology
Afimkibart (PF-06480605) is a human IgG1 monoclonal antibody targeting tumor necrosis factor-like ligand 1A (TL1A). Afimkibart can be used in the research of inflammatory bowel disease .

HY-P99934

Eftozanermin alfa 1 Publications Verification ABBV-621	Apoptosis	Cancer
Eftozanermin alfa (ABBV-621) is a second-generation tumor necrosis factor-related apoptosis-inducing ligand receptor (TRAIL-R) agonist. Eftozanermin alfa induces apoptosis in tumor cells by activation of death receptors 4/5. Eftozanermin alfa can be used for the research of multiple solid and heme malignancies .

HY-P990070

Zigakibart BION-1301	TNF Receptor	Inflammation/Immunology Cancer
Zigakibart (BION-1301) is an IgG4-kappa, anti-TNFSF13 (tumor necrosis factor (TNF) superfamily member 13, APRIL, CD256) humanized monoclonal antibody. Zigakibart shows anti-inflammatory activity .

HY-P99265

Mapatumumab HGS-ETR1; Anti-Human TNFRSF10A Recombinant Antibody	Inhibitory Antibodies	Cancer
Mapatumumab (HGS-ETR1) is a fully human IgG2 agonistic monoclonal antibody that targets tumor necrosis factor-related apoptosis-inducing ligand receptor 1 (TRAIL-R1). Mapatumumab can be used for the research of cancer .

HY-P99771

Onercept	Inhibitory Antibodies	Inflammation/Immunology
Onercept is a recombinant soluble human tumor necrosis factor-alpha p55 receptor for use in Crohn's disease research .

HY-P991149

Nesfrotamig	TNF Receptor	Cancer
Nesfrotamig is a humanized immunoglobulin (H-γ1-scFv-L-κ) dimer monoclonal antibody targeting human epidermal growth factor receptor 2 (ERBB2) and human tumor necrosis factor receptor superfamily member 9 (TNFRSF9). Nesfrotamig is promising for research of cancers, especially in ERBB2-positive related tumor diseases, such as breast cancer and gastric cancer .

HY-P99782

Opinercept	TNF Receptor	Inflammation/Immunology
Opinercept is a recombinant fusion protein comprising an TNFRSF1B fused to a human IgG1 Fc . Opinercept is a tumor necrosis factor-alpha (TNF-alpha) inhibitor. Opinercept can be used for the research of rheumatoid arthritis (RA) .

HY-P991125

Cenzestotug	TNF Receptor	Inflammation/Immunology Cancer
Cenzestotug is a monoclonal antibody targeting human tumor necrosis factor receptor superfamily member 4 (TNFRSF4). Cenzestotug activates relevant immune cells by binding to TNFRSF4, exerting immunostimulatory and antitumor activities. Cenzestotug is promising for research of cancer immunotherapy .

HY-P991155

Ramantamig	CD3 TNF Receptor	Cancer
Ramantamig is a humanized monoclonal antibody targeting human CD3ε, GPRC5D, and TNFRSF17 (tumor necrosis factor receptor superfamily member 17)。Ramantamig is promising for research of cancers, especially hematological malignancies such as multiple myeloma .

HY-P991151

Opamtistomig	PD-1/PD-L1 TNF Receptor	Cancer
Opamtistomig is a humanized immunoglobulin (H-γ1-scFv-L-κ) dimer monoclonal antibody targeting human programmed death ligand 1 (PD-L1), CD274 and tumor necrosis factor receptor superfamily member 9 (TNFRSF9). Opamtistomig is promising for research of various solid tumors and hematological malignancies .

HY-P991178

BMS-986156	TNF Receptor	Cancer
BMS-986156 is a fully humanized IgG1 agonist monoclonal antibody agonist corticosteroid-induced tumor necrosis factor receptor-related protein (GITR). BMS-986156 binds to GITR and promotes activation of T effector cells and inactivates T regulatory cells. BMS-986156 is indicated for use in advanced solid tumor studies .

HY-P99940

Remtolumab ABT-122	TNF Receptor Interleukin Related	Inflammation/Immunology
Remtolumab (ABT-122) is a dual-variable domain immunoglobulin that neutralises both tumor necrosis factor α (TNFα) and IL-17A. Remtolumab shows dual inhibition of TNFα and IL-17A. Remtolumab can be used for rheumatoid arthritis (RA) research .

HY-P991180

TRX-518	TNF Receptor	Cancer
TRX-518 is a humanized agonist antibody targeting glucocorticoid-induced tumor necrosis factor receptor (GITR). TRX-518 specifically targets GITR⁺ Tregs and CD45RA⁻Foxp3⁺ effector Tregs (eTregs) among regulatory T cells (Tregs), reducing the number of Tregs in circulation and within tumors. TRX-518 is promising for research of cancers .

HY-P990680

Anti-Mouse CD40 Antibody (FGK4.5/FGK45)	Inhibitory Antibodies	Inflammation/Immunology
Anti-Mouse CD40 Antibody (FGK4.5/FGK45) is a rat-derived IgG2a monoclonal antibody targeting mouse CD40. CD40 is a type I transmembrane glycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD40 can act as a co-stimulatory molecule to activate B cells, dendritic cells, monocytes, and other APCs, promoting anti-tumor T cell responses.

HY-P3385

Rilunermin alfa SCB-313	Drug Derivative Apoptosis	Cancer
Rilunermin alfa (SCB-313) is a recombinant fusion protein composed of the human C-propeptide of alpha1(I) collagen (Trimer-Tag) to the C-terminus of the mature human tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL; Apo2L). Rilunermin alfa has potential pro-apoptotic and antineoplastic activities .

HY-P99810

Quisovalimab AVTX-002; AEVI 002; SAR 252067; CERC-002; MDGN-002	SARS-CoV	Cardiovascular Disease
Quisovalimab (AVTX-002; AEVI 002; SAR 252067) is a human monoclonal antibody against LIGHT, a tumor necrosis factor (TNF)-related cytokine (TNFSF14) that plays an important role in acute respiratory distress syndrome (ARDS) and cytokine release syndrome (CRS) COVID-19. Quisovalimab can be used in COVID-19 acute respiratory distress syndrome and other studies .

Species:	Human (134) Rhesus Macaque (17) Rat (28) Mouse (61) Bovine (1) Cynomolgus (28) Rabbit (5) Canine (6) Pig (1)
Tag:	His (146) Tag Free (27) Avi (23) Myc (4) GST (1) Fc (112) Flag (8)
Source:	HEK293 (230) CHO (1) Sf9 insect cells (5) P. pastoris (6) E. coli (41)

Cat. No.	Compare	Product Name	Species	Source

HY-P70697

	TNF-alpha/TNFSF2 Protein, Rat Maximum Cited Publications 6 Publications Verification Tumor necrosis factor; Cachectin; TNF-Alpha; Tumor necrosis factor Ligand Superfamily Member 2; TNF-a; Tumor necrosis factor; Membrane Form; Tumor necrosis factor; Soluble Form; Tnf; Tnfa; Tnfsf2	Rat	E. coli
	Tumour Necrosis Factor alpha (TNF alpha) is a potent pro-inflammatory cytokine. TNF alpha binds to its receptors, mainly TNFR1 and TNFR2, and then transmits molecular signals for biological functions such as inflammation and cell death. TNF alpha stimulates NF-κB pathway via TNFR2 promotes cancer growth, invasion, and metastasis. Anti-TNF-α MAb significantly suppresses the tumor development in colitis-associated cancer (CAC) mouse. TNF alpha as a proneurogenic factor activates the SAPK/JNK Pathway and can facilitate neuronal replacement and brain repair in response to brain injury .

HY-P70571

	TNF-alpha/TNFSF2 Protein, Mouse (147a.a) 2 Publications Verification Tumor necrosis factor; Cachectin; TNF-Alpha; Tumor necrosis factor Ligand Superfamily Member 2; TNF-a; Tumor necrosis factor; Membrane Form; Tumor necrosis factor; Soluble Form; Tnf; Tnfa; Tnfsf2	Mouse	E. coli
	Tumour Necrosis Factor alpha (TNF alpha) is a potent pro-inflammatory cytokine. TNF alpha binds to its receptors, mainly TNFR1 and TNFR2, and then transmits molecular signals for biological functions such as inflammation and cell death. TNF alpha stimulates NF-κB pathway via TNFR2 promotes cancer growth, invasion, and metastasis. Anti-TNF-α MAb significantly suppresses the tumor development in colitis-associated cancer (CAC) mouse. TNF alpha as a proneurogenic factor activates the SAPK/JNK Pathway and can facilitate neuronal replacement and brain repair in response to brain injury.TNF-alpha/TNFSF2 Protein, Mouse is a recombinant protein consisting of 147 amino acids (D89-L235) and is produced in E. coli.

HY-P70426G

	GMP TNF-alpha/TNFSF2 Protein, Human 1 Publications Verification Tumor necrosis factor; Cachectin; TNF-Alpha; Tumor necrosis factor Ligand Superfamily Member 2; TNF-a; TNF; TNFA; TNFSF2	Human	E. coli
	Tumour Necrosis Factor alpha (TNF alpha) is a potent pro-inflammatory cytokine. TNF alpha binds to its receptors, mainly TNFR1 and TNFR2, and then transmits molecular signals for biological functions such as inflammation and cell death. TNF alpha stimulates NF-κB pathway via TNFR2 promotes cancer growth, invasion, and metastasis. Anti-TNF-α MAb significantly suppresses the tumor development in colitis-associated cancer (CAC) mouse. TNF alpha as a proneurogenic factor activates the SAPK/JNK Pathway and can facilitate neuronal replacement and brain repair in response to brain injury. GMP TNF-alpha/TNFSF2 Protein, Human is a recombinant protein consisting of 157 amino acids (V77-L233) and is produced in E. coli.

HY-P73443

	TNF-alpha/TNFSF2 Protein, Canine Tumor necrosis factor; Cachectin; TNF-Alpha; Tnf; Tnfa; Tnfsf2; ICD1	Canine	E. coli
	Tumour Necrosis Factor alpha (TNF alpha) is a potent pro-inflammatory cytokine. TNF alpha binds to its receptors, mainly TNFR1 and TNFR2, and then transmits molecular signals for biological functions such as inflammation and cell death. TNF alpha stimulates NF-κB pathway via TNFR2 promotes cancer growth, invasion, and metastasis. Anti-TNF-α MAb significantly suppresses the tumor development in colitis-associated cancer (CAC) mouse. TNF alpha as a proneurogenic factor activates the SAPK/JNK Pathway and can facilitate neuronal replacement and brain repair in response to brain injury. TNF-alpha/TNFSF2 Protein, Canine is a recombinant protein produced in E. coli.

HY-P73444

	TNF-alpha/TNFSF2 Protein, Cynomolgus Tumor necrosis factor; Cachectin; TNF-Alpha; Tnf; Tnfa; Tnfsf2; ICD1	Cynomolgus	E. coli
	Tumour Necrosis Factor alpha (TNF alpha) is a potent pro-inflammatory cytokine. TNF alpha binds to its receptors, mainly TNFR1 and TNFR2, and then transmits molecular signals for biological functions such as inflammation and cell death. TNF alpha stimulates NF-κB pathway via TNFR2 promotes cancer growth, invasion, and metastasis. Anti-TNF-α MAb significantly suppresses the tumor development in colitis-associated cancer (CAC) mouse. TNF alpha as a proneurogenic factor activates the SAPK/JNK Pathway and can facilitate neuronal replacement and brain repair in response to brain injury. TNF-alpha/TNFSF2 Protein, Cynomolgus is a recombinant protein consisting of 157 amino acids (V77-L233) and is produced in E. coli.

HY-P73445

	TNF-alpha/TNFSF2 Protein, Ferret Tumor necrosis factor; Cachectin; TNF-Alpha; Tnf; Tnfa; Tnfsf2; ICD1	Others	E. coli
	Tumour Necrosis Factor alpha (TNF alpha) is a potent pro-inflammatory cytokine. TNF alpha binds to its receptors, mainly TNFR1 and TNFR2, and then transmits molecular signals for biological functions such as inflammation and cell death. TNF alpha stimulates NF-κB pathway via TNFR2 promotes cancer growth, invasion, and metastasis. Anti-TNF-α MAb significantly suppresses the tumor development in colitis-associated cancer (CAC) mouse. TNF alpha as a proneurogenic factor activates the SAPK/JNK Pathway and can facilitate neuronal replacement and brain repair in response to brain injury. TNF-alpha/TNFSF2 Protein, Ferret is a recombinant protein consisting of 157 amino acids (V77-L233) and is produced in E. coli.

HY-P70800

	TNF-alpha/TNFSF2 protein, Rabbit 5 Publications Verification Tumor necrosis factor; Cachectin; TNF-Alpha; Tumor necrosis factor Ligand Superfamily Member 2; TNF-a; TNF; TNFA; TNFSF2	Rabbit	E. coli
	Tumour Necrosis Factor alpha (TNF alpha) is a potent pro-inflammatory cytokine. TNF alpha binds to its receptors, mainly TNFR1 and TNFR2, and then transmits molecular signals for biological functions such as inflammation and cell death. TNF alpha stimulates NF-κB pathway via TNFR2 promotes cancer growth, invasion, and metastasis. Anti-TNF-α MAb significantly suppresses the tumor development in colitis-associated cancer (CAC) mouse. TNF alpha as a proneurogenic factor activates the SAPK/JNK Pathway and can facilitate neuronal replacement and brain repair in response to brain injury. TNF-alpha/TNFSF2 protein, Rabbit is a recombinant protein consisting of 158 amino acids (V78-L235) and is produced in E. coli.

HY-P70426A

	TNF alpha/TNFSF2 protein, Human (His) 2 Publications Verification Tumor necrosis factor; Cachectin; TNF-Alpha; Tumor necrosis factor Ligand Superfamily Member 2; TNF-a; TNF; TNFA; TNFSF2	Human	E. coli
	Tumour Necrosis Factor alpha (TNF alpha) is a potent pro-inflammatory cytokine. TNF alpha binds to its receptors, mainly TNFR1 and TNFR2, and then transmits molecular signals for biological functions such as inflammation and cell death. TNF alpha stimulates NF-κB pathway via TNFR2 promotes cancer growth, invasion, and metastasis. Anti-TNF-α MAb significantly suppresses the tumor development in colitis-associated cancer (CAC) mouse. TNF alpha as a proneurogenic factor activates the SAPK/JNK Pathway and can facilitate neuronal replacement and brain repair in response to brain injury. TNF alpha/TNFSF2 protein, Human (His) is a recombinant protein with a C-Terminal His label, It consists of 157 amino acids (V77-L233) and is produced in CHO cells.

HY-P77543

	TNF-alpha/TNFSF2 Protein, Cynomolgus (Biotinylated) Tumor necrosis factor; Cachectin; TNF-Alpha; Tnf; Tnfa; Tnfsf2; ICD1	Cynomolgus	E. coli
	Tumour Necrosis Factor alpha (TNF alpha) is a potent pro-inflammatory cytokine. TNF alpha binds to its receptors, mainly TNFR1 and TNFR2, and then transmits molecular signals for biological functions such as inflammation and cell death. TNF alpha stimulates NF-κB pathway via TNFR2 promotes cancer growth, invasion, and metastasis. Anti-TNF-α MAb significantly suppresses the tumor development in colitis-associated cancer (CAC) mouse. TNF alpha as a proneurogenic factor activates the SAPK/JNK Pathway and can facilitate neuronal replacement and brain repair in response to brain injury. TNF-alpha/TNFSF2 Protein, Cynomolgus (Biotinylated) is a biotinylated recombinant protein consisting of 157 amino acids (V77-L233) and is produced in E. coli.

HY-P700283

	TNF-alpha/TNFSF2 Protein, Pig (N-His) Tumor necrosis factor; TNF; Cachectin; TNF-alpha; Tumor necrosis factor ligand superfamily member 2; TNF-a; Tumor necrosis factor alpha; TNFA; TNFSF2	Pig	E. coli
	TNF-α/TNFSF2 protein is a cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and has multiple biological functions. It has the ability to induce cell death in specific tumor cell lines, serves as a potent pyrogen, can cause fever through direct action or stimulation of interleukin-1 secretion, and is involved in the induction of cachexia. TNF-alpha/TNFSF2 Protein, Pig (N-His) is the recombinant Pig-derived TNF-alpha/TNFSF2 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P70801

	TNFRSF1A Protein, Human (His) Tumor necrosis factor receptor superfamily member 1A; Tumor necrosis factor receptor 1; TNF-R1; Tumor necrosis factor receptor type I; TNF-RI; TNFR-I; TNFAR; TNFR1	Human	E. coli
	TNFRSF1A (TNF RI) protein has a high ability to bind with tumor necrosis factor-alpha (TNF-α). TNFRSF1A is a STAT3 target gene that regulates the NF-κB pathway. TNFRSF1A activate NF-κB, mediate apoptosis, and function as a regulator of inflammation. TNFRSF1A Protein, Human (His) is expressed by E. coli and has a transmembrane region (I22-T211) with a 6*His tag at the N-terminus.

HY-P70345

	TNFRSF3/LTBR Protein, Human (HEK293, His) rHuTumor necrosis factor receptor superfamily member 3/TNFRSF3, His; Tumor necrosis factor Receptor Superfamily Member 3; Lymphotoxin-Beta Receptor; Tumor necrosis factor C Receptor; Tumor necrosis factor Receptor 2-Related Protein; Tumor necrosis factor Receptor Type III; TNF-RIII; TNFR-III; LTBR; D12S370; TNFCR; TNFR3; TNFRSF3	Human	HEK293
	TNFRSF3/LTBR Protein, Human (HEK293, His) is a cell surface receptor for apoptotic and cytokine-released lymphotoxins involved in activation of gene transcription programs and cell death, and is important in immune development and host defense. TNFRSF3/LTBR Protein, Human (HEK293, His) is expressed by HEK293 cells and is a transmembrane protein (L228-W248) with a His tag at the C-terminus.

HY-P704932

	TNFRSF3/LTBR Protein, Human (HEK293, His-Avi) rHuTumor necrosis factor receptor superfamily member 3/TNFRSF3, His; Tumor necrosis factor Receptor Superfamily Member 3; Lymphotoxin-Beta Receptor; Tumor necrosis factor C Receptor; Tumor necrosis factor Receptor 2-Related Protein; Tumor necrosis factor Receptor Type III; TNF-RIII; TNFR-III; LTBR; D12S370; TNFCR; TNFR3; TNFRSF3	Human	HEK293

HY-P72806

	TNFRSF3/LTBR Protein, Human (HEK293, Fc) Tumor necrosis factor Receptor Superfamily Member 3; Lymphotoxin-Beta Receptor; Tumor necrosis factor C Receptor; Tumor necrosis factor Receptor 2-Related Protein; Tumor necrosis factor Receptor Type III; TNF-RIII; TNFR-III; LTBR; D12S370; TNFCR; TNFR3; TNFRSF3	Human	HEK293
	TNFRSF3/LTBR Protein, Human (HEK293, Fc) is a cell surface receptor for apoptotic and cytokine-released lymphotoxins involved in activation of gene transcription programs and cell death, and is important in immune development and host defense. TNFRSF3/LTBR Protein, Human (HEK293, Fc) is expressed by HEK293 cells and is a transmembrane protein (L228-W248) with a Fc tag at the C-terminus.

HY-P705130

	TNFRSF3/LTBR Protein, Human (Biotinylated, HEK293, His-Avi) rHuTumor necrosis factor receptor superfamily member 3/TNFRSF3, His; Tumor necrosis factor Receptor Superfamily Member 3; Lymphotoxin-Beta Receptor; Tumor necrosis factor C Receptor; Tumor necrosis factor Receptor 2-Related Protein; Tumor necrosis factor Receptor Type III; TNF-RIII; TNFR-III; LTBR; D12S370; TNFCR; TNFR3; TNFRSF3	Human	HEK293

HY-P700291

	TNF-alpha/TNFSF2 Protein, Human (177a.a, His) Tumor necrosis factor; Cachectin; TNF-Alpha; Tumor necrosis factor Ligand Superfamily Member 2; TNF-a; TNF; TNFA; TNFSF2	Human	E. coli
	TNF-α/TNFSF2 protein is a macrophage-secreted cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR, inducing tumor cell death and acting as a pyrogen. It is associated with cachexia and stimulates cell proliferation and differentiation. TNF-alpha/TNFSF2 Protein, Human (177a.a, His) is the recombinant human-derived TNF-alpha/TNFSF2 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P71126

	TNF RII/TNFRSF1B Protein, Human (174a.a, HEK293, His) Tumor necrosis factor receptor superfamily member 1B; Tumor necrosis factor receptor 2; TNF-R2; Tumor necrosis factor receptor type II; TNF-RII; TNFR-II; p75; p80 TNF-alpha receptor; TNFRII; TNF RII	Human	HEK293
	TNFRII (TNFRSF1B) protein has a high ability to bind with tumor necrosis factor-alpha (TNF-α). TNFRII has pro-apoptotic function. TNFRII recruits TRAF2, induces gene expression and intensively crosstalks with TNF-R1. TNFRII selectively enhances the induction of apoptosis by the death receptor TNFRI. TNFRII Protein, Human (174a.a, HEK293, His) is expressed by HEK293 and has a transmembrane region (K288-S461) with 6*His tag at the C-terminus.

HY-P71914

	TNF RII/TNFRSF1B Protein, Human (183a.a) CD120b; p75; p75 TNF receptor; p75TNFR; p80 TNF alpha receptor; p80 TNF-alpha receptor; Soluble TNFR1B variant 1; TBP-2; TBPII; TNF R II; TNF R2; TNF R75; TNF-R2; TNF-RII; TNFBR; TNFR-II; TNFR1B; TNFR2; TNFR80; TNFRII ; Tnfrsf1b; TNR1B_HUMAN; Tumor necrosis factor beta receptor; Tumor necrosis factor binding protein 2; Tumor necrosis factor receptor 2; Tumor necrosis factor receptor superfamily member 1B; Tumor necrosis factor receptor type II; Tumor necrosis factor-binding protein 2	Human	E. coli
	The TNFRII protein is a receptor with high affinity for TNFSF2/TNF-α and low affinity for TNFSF1/lymphotoxin-α, and plays a key role in mediating the metabolic effects of TNF-α. The TRAF1/TRAF2 complex recruits BIRC2 and BIRC3 to TNFRSF1B/TNFR2 to regulate the apoptotic pathway. TNFRII Protein, Human (183a.a) is the recombinant human-derived TNFRII protein, expressed by E. coli , with tag free.

HY-P70536

	TNF RII/TNFRSF1B Protein, Human (183a.a, HEK293, mFc) TNF-RII; TNFRII; TNF RII; Tumor necrosis factor receptor superfamily member 1B; TNFRSF1B; Tumor necrosis factor receptor 2; TNF-R2; Tumor necrosis factor receptor type II; p75; p80 TNF-alpha receptor; CD120b	Human	HEK293
	TNFRII (TNFRSF1B) protein has a high ability to bind with tumor necrosis factor-alpha (TNF-α). TNFRII has pro-apoptotic function. TNFRII recruits TRAF2, induces gene expression and intensively crosstalks with TNF-R1. TNFRII selectively enhances the induction of apoptosis by the death receptor TNFRI. TNF RII/TNFRSF1B Protein, Human (183a.a, HEK293, mFc) is expressed by HEK293 and has a transmembrane region (P24-T206) with mFc tag at the C-terminus.

HY-P78527A

	TNF-alpha/TNFSF2 Protein, Human (HEK293, His) NF-alpha; TNF; TNFA; Tumor necrosis factor	Human	HEK293
	TNF-α/TNFSF2 protein is a macrophage-secreted cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR, inducing tumor cell death and acting as a pyrogen. It is associated with cachexia and stimulates cell proliferation and differentiation. TNF-alpha/TNFSF2 Protein, Human (HEK293, His) is the recombinant human-derived TNF-alpha/TNFSF2 protein, expressed by HEK293 , with C-His labeled tag.

HY-P71648

	C1QTNF3/CTRP3 Protein, Human (His) C1ATNF3; C1q and Tumor necrosis factor related protein 3 Complement C1q Tumor necrosis factor related protein 3 ; Complement C1q Tumor necrosis factor-related protein 3; Corcs; CORS 26; Cors; CORS26; CTRP3; FLJ37576	Human	E. coli
	C1QTNF3/CTRP3 Protein is a secreted protein of the C1q/ TNF-associated protein (CTRPs) family. C1QTNF3/CTRP3 Protein by participating in the TGF-尾1/Smad, Sirtuin 1/NF-魏B, AMPK and Signaling pathways such as LAMP1/JIP2/JNK have extensive effects on tumor, inflammation, metabolism, and insulin sensitization. C1QTNF3/CTRP3 Protein, Human (His) is the recombinant human-derived C1QTNF3/CTRP3 protein, expressed by E. coli , with N-His labeled tag.

HY-P700419

	TNF-beta/TNFSF1 Protein, Human (HEK293, His) LTA; lymphotoxin alpha (TNF superfamily, member 1); LT; TNFB; TNFSF1; lymphotoxin alpha; OTTHUMP00000165897; Tumor necrosis factor beta; Tumor necrosis factor ligand superfamily member 1; TNF-beta; LT-alpha	Human	HEK293
	TNF-β protein acts as a homotrimeric cytokine that binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR, and TNFRSF14/HVEM. TNF-beta/TNFSF1 Protein, Human (HEK293, His) is the recombinant human-derived TNF-beta/TNFSF1 protein, expressed by HEK293 , with N-6*His labeled tag.

HY-P75261

	EDAR Protein, Rat (HEK293, Fc) Tumor necrosis factor receptor superfamily member EDAR; EDA-A1 receptor; EDAR	Rat	HEK293
	EDAR Protein is a typical Tumor Necrosis Factor receptor (TNFR) family member. EDAR is a receptor for EDA isoform A1. Its binding results in recruitment of the intracellular EDAR-associated death domain (EDARADD) adapter protein and simultaneous activation of NF-kappa-B and JNK signaling pathways, potentially leading to various cellular responses. Additionally, EDAR may play a role in promoting caspase-independent cell death. EDAR Protein, Rat (HEK293, Fc) is the recombinant rat-derived EDAR protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P75262

	EDAR Protein, Human (HEK293, His) Tumor necrosis factor receptor superfamily member EDAR; EDA-A1 receptor; EDAR	Human	HEK293
	EDAR Protein, a receptor for EDA isoform A1, activates NF-kappa-B and JNK signaling pathways upon binding, eliciting diverse cellular responses. It may also contribute to caspase-independent cell death. EDAR forms a complex with EDARADD and associates with signaling molecules like TRAF1, TRAF2, TRAF3, and NIK, highlighting its participation in intricate signaling cascades. EDAR Protein, Human (HEK293, His) is the recombinant human-derived EDAR protein, expressed by HEK293 , with C-His labeled tag.

HY-P75263

	EDAR Protein, Human (HEK293, Fc) Tumor necrosis factor receptor superfamily member EDAR; EDA-A1 receptor; EDAR	Human	HEK293
	EDAR Protein, a receptor for EDA isoform A1, activates NF-kappa-B and JNK signaling pathways upon binding, eliciting diverse cellular responses. It may also contribute to caspase-independent cell death. EDAR forms a complex with EDARADD and associates with signaling molecules like TRAF1, TRAF2, TRAF3, and NIK, highlighting its participation in intricate signaling cascades. EDAR Protein, Human (HEK293, Fc) is the recombinant human-derived EDAR protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P76895

	EDAR Protein, Cynomolgus (HEK293, Fc) Tumor necrosis factor receptor superfamily member EDAR; EDA-A1 receptor; EDAR	Cynomolgus	HEK293
	EDAR Protein, a receptor for EDA isoform A1, activates NF-kappa-B and JNK signaling pathways upon binding, eliciting diverse cellular responses. It may also contribute to caspase-independent cell death. EDAR forms a complex with EDARADD and associates with signaling molecules like TRAF1, TRAF2, TRAF3, and NIK, highlighting its participation in intricate signaling cascades. EDAR Protein, Cynomolgus (HEK293, Fc) is the recombinant cynomolgus-derived EDAR protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P76896

	EDAR Protein, Cynomolgus (HEK293, His) Tumor necrosis factor receptor superfamily member EDAR; EDA-A1 receptor; EDAR	Cynomolgus	HEK293
	EDAR Protein, a receptor for EDA isoform A1, activates NF-kappa-B and JNK signaling pathways upon binding, eliciting diverse cellular responses. It may also contribute to caspase-independent cell death. EDAR forms a complex with EDARADD and associates with signaling molecules like TRAF1, TRAF2, TRAF3, and NIK, highlighting its participation in intricate signaling cascades. EDAR Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived EDAR protein, expressed by HEK293 , with C-His labeled tag.

HY-P700612

	TNF-beta/TNFSF1 Protein, Human (Biotinylated, HEK293, His-Avi) LTA; lymphotoxin alpha (TNF superfamily, member 1); LT; TNFB; TNFSF1; lymphotoxin alpha; OTTHUMP00000165897; Tumor necrosis factor beta; Tumor necrosis factor ligand superfamily member 1; TNF-beta; LT-alpha	Human	HEK293
	TNF-β protein acts as a homotrimeric cytokine that binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR, and TNFRSF14/HVEM. TNF-beta/TNFSF1 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived TNF-beta/TNFSF1 protein, expressed by HEK293 , with N-Avi, N-6*His labeled tag.

HY-P703918

	CD30 Ligand/TNFSF8 Protein, Cynomolgus (HEK293, hFc) Tumor necrosis factor (ligand) superfamily; member 8	Cynomolgus	HEK293
	CD30 Ligand/TNFSF8 Protein, Cynomolgus (HEK293, hFc) is the recombinant cynomolgus-derived CD30 Ligand/TNFSF8 protein, expressed by HEK293, with N-hFc tag.

HY-P703919

	CD30 Ligand/TNFSF8 Protein, Cynomolgus (HEK293, His) Tumor necrosis factor (ligand) superfamily; member 8	Cynomolgus	HEK293
	CD30 Ligand/TNFSF8 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived CD30 Ligand/TNFSF8 protein, expressed by HEK293, with N-His tag.

HY-P70363

	TNFRSF3/LTBR Protein, Mouse (HEK293, Fc) rMuTumor necrosis factor receptor superfamily member 3/LTBR, Fc; Tumor necrosis factor receptor superfamily member 3; Lymphotoxin-beta receptor; Ltbr; Tnfcr; Tnfrsf3	Mouse	HEK293
	TNFRSF3/LTBR Protein, Mouse (HEK293, Fc) is a cell surface receptor for apoptotic and cytokine-released lymphotoxins involved in activation of gene transcription programs and cell death, and is important in immune development and host defense. TNFRSF3/LTBR Protein, Mouse (HEK293, Fc) is expressed by HEK293 cells and is a transmembrane protein with a Fc tag at the C-terminus.

HY-P71913

	TL1A/TNFSF15 Protein, Human MGC129934; MGC129935; TL1 A; tl1; tl1a; tnf ligand related molecule 1; TNF ligand-related molecule 1; tnf superfamily ligand tl1a; TNF15_HUMAN; TNFSF15; Tumor necrosis factor ligand; superfamily member 15; Tumor necrosis factor ligand superfamily member 15; Tumor necrosis factor ligand superfamily member 15, secreted form	Human	E. coli
	TL1A/TNFSF15 Protein, the receptor for TNFRSF25 and TNFRSF6B, activates NF-kappa-B and promotes caspase activation, leading to apoptosis. It also inhibits vascular endothelial growth and angiogenesis in vitro. Operating as a homotrimer, it plays a crucial role in diverse cellular processes, including immune response and apoptosis regulation. TL1A/TNFSF15 Protein, Human is the recombinant human-derived TL1A/TNFSF15 protein, expressed by E. coli , with tag free.

HY-P70489

	HVEM/TNFRSF14 Protein, Human (HEK293, His) Tumor necrosis factor Receptor Superfamily Member 14; Herpes Virus Entry Mediator A; Herpesvirus Entry Mediator A; HveA; Tumor necrosis factor Receptor-Like 2; TR2; CD270; TNFRSF14; HVEA; HVEM	Human	HEK293
	HVEM (herpes virus entry mediator, TNFRSF14, CD270) is a member of the tumor necrosis factor receptor superfamily (TNFRSF). HVEM is a bidirectional molecular switch that transduces positive and negative signals. HVEM can deliver proinflammatory and survival signals when engaged by BTLA or LIGHT, stimulating lymphocyte proliferation, activation, and inducing inflammatory reactions. While, HVEM binds to CD160 and BTLA, inhibiting T- and B-lymphocyte activation and proliferation. HVEM/TNFRSF14 Protein, Human (HEK293, His) is a recombinant protein with a C-Terminal His label, It is produced in HEK293 cells.

HY-P70951

	HVEM/TNFRSF14 Protein, Rhesus macaque (HEK293, Fc) Tumor necrosis factor Receptor Superfamily Member 14; Herpes Virus Entry Mediator A; Herpesvirus Entry Mediator A; HveA; Tumor necrosis factor Receptor-Like 2; TR2; CD270; TNFRSF14; HVEA; HVEM	Rhesus Macaque	HEK293
	HVEM (herpes virus entry mediator, TNFRSF14, CD270) is a member of the tumor necrosis factor receptor superfamily (TNFRSF). HVEM is a bidirectional molecular switch that transduces positive and negative signals. HVEM can deliver proinflammatory and survival signals when engaged by BTLA or LIGHT, stimulating lymphocyte proliferation, activation, and inducing inflammatory reactions. While, HVEM binds to CD160 and BTLA, inhibiting T- and B-lymphocyte activation and proliferation. HVEM/TNFRSF14 Protein, Rhesus macaque (HEK293, Fc) is a recombinant protein with a C-Terminal Fc label, It consists of 167 amino acids (P37-V203) and is produced in HEK293 cells.

HY-P71992

	HVEM/TNFRSF14 Protein, Mouse (HEK293, hFc) Tnfrsf14; hvem; Tumor necrosis factor receptor superfamily member 14; Herpes virus entry mediator A; Herpesvirus entry mediator A; HveA; Tumor necrosis factor receptor-like 2; TR2; CD antigen CD270	Mouse	HEK293
	HVEM (herpes virus entry mediator, TNFRSF14, CD270) is a member of the tumor necrosis factor receptor superfamily (TNFRSF). HVEM is a bidirectional molecular switch that transduces positive and negative signals. HVEM can deliver proinflammatory and survival signals when engaged by BTLA or LIGHT, stimulating lymphocyte proliferation, activation, and inducing inflammatory reactions. While, HVEM binds to CD160 and BTLA, inhibiting T- and B-lymphocyte activation and proliferation. HVEM/TNFRSF14 Protein, Mouse (HEK293, Fc) is a recombinant protein with a C-Terminal Fc label, It consists of 169 amino acids (Q39-V207) and is produced in HEK293 cells.

HY-P72025

	TNF RII/TNFRSF1B Protein, Human (HEK293, hFc) Tumor necrosis factor receptor 2; TNF-R2; Tumor necrosis factor receptor type II; TNF-RII; TNFR-II; p75; p80 TNF-alpha receptor; CD120b; Etanercept; TBP-2; TBPII	Human	HEK293
	TNFRII (TNFRSF1B) protein has a high ability to bind with tumor necrosis factor-alpha (TNF-α). TNFRII has pro-apoptotic function. TNFRII recruits TRAF2, induces gene expression and intensively crosstalks with TNF-R1. TNFRII selectively enhances the induction of apoptosis by the death receptor TNFRI. TNFRII Protein, Human (HEK293, hFc) is expressed by HEK293 and has a transmembrane region (L23-D257) with hFc tag at the C-terminus.

HY-P700452

	HVEM/TNFRSF14 Protein, Human (HEK293, hFc) Tumor necrosis factor Receptor Superfamily Member 14; Herpes Virus Entry Mediator A; Herpesvirus Entry Mediator A; HveA; Tumor necrosis factor Receptor-Like 2; TR2; CD270; TNFRSF14; HVEA; HVEM	Human	HEK293
	The HVEM/TNFRSF14 protein acts as a receptor for four ligands, including TNFSF14/LIGHT, LTA/lymphotoxin-α, BTLA, and CD160, forming a complex stimulatory and inhibitory signaling network. Utilizes the TRAF2-TRAF3 E3 ligase pathway to promote the survival and differentiation of immune cells. HVEM/TNFRSF14 Protein, Human (HEK293, hFc) is the recombinant human-derived HVEM/TNFRSF14 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P704665

	HVEM/TNFRSF14 Protein, Human (HEK293, mFc) Tumor necrosis factor Receptor Superfamily Member 14; Herpes Virus Entry Mediator A; Herpesvirus Entry Mediator A; HveA; Tumor necrosis factor Receptor-Like 2; TR2; CD270; TNFRSF14; HVEA; HVEM	Human	HEK293
	The HVEM/TNFRSF14 protein acts as a receptor for four ligands, including TNFSF14/LIGHT, LTA/lymphotoxin-α, BTLA, and CD160, forming a complex stimulatory and inhibitory signaling network. Utilizes the TRAF2-TRAF3 E3 ligase pathway to promote the survival and differentiation of immune cells. HVEM/TNFRSF14 Protein, Human (HEK293, mFc) is the recombinant human-derived HVEM/TNFRSF14 protein, expressed by HEK293, with C-mFc labeled tag.

HY-P75589

	BAFF/TNFSF13B Protein, Canine (HEK293, Fc) Tumor necrosis factor ligand superfamily member 13B; BAFF; TALL-1	Canine	HEK293
	The BAFF/TNFSF13B protein is part of the TNF family and is critical in the regulation of immune responses and cell survival. It is also called B cell activating factor and plays a crucial role in B cell development, activation and survival by binding to receptors such as BAFF-R. BAFF/TNFSF13B Protein, Canine (HEK293, Fc) is the recombinant canine-derived BAFF/TNFSF13B protein, expressed by HEK293 , with N-hFc labeled tag. The total length of BAFF/TNFSF13B Protein, Canine (HEK293, Fc) is 150 a.a., with molecular weight of ~45.5 kDa.

HY-P76562

	RANK/TNFRSF11A Protein, Rat (HEK293, Fc) Tumor necrosis factor receptor superfamily member 11A; ODFR; CD265	Rat	HEK293
	RANK (TNFRSF11A) is a receptor activator of nuclear factor κB (NF-κB), which is involved in bone metabolism and immune system function. RANK is mainly expressed by osteoblasts/stromal cells, and is associated with the formation of giant cell tumor of bone (GCTBs) . RANK combined with RANKL ligand activated the RANKL/RANK/ OPG system to regulate bone resorption . RANKL/RANK is also a regulator of dendritic cell (DC)-T cell interaction, which is associated with mammary epithelial formation and central nervous system thermoregulation in lactating female . RANK/TNFRSF11A Protein, Rat (HEK293, Fc) produced by HEK293 cells with C-terminal hFc-tag.

HY-P76563

	RANK/TNFRSF11A Protein, Rat (HEK293, His) Tumor necrosis factor receptor superfamily member 11A; ODFR; CD265	Rat	HEK293
	RANK (TNFRSF11A) is a receptor activator of nuclear factor κB (NF-κB), which is involved in bone metabolism and immune system function. RANK is mainly expressed by osteoblasts/stromal cells, and is associated with the formation of giant cell tumor of bone (GCTBs) . RANK combined with RANKL ligand activated the RANKL/RANK/ OPG system to regulate bone resorption . RANKL/RANK is also a regulator of dendritic cell (DC)-T cell interaction, which is associated with mammary epithelial formation and central nervous system thermoregulation in lactating female . RANK/TNFRSF11A Protein, Rat (HEK293, His) produced by HEK293 cells with C-terminal His-tag.

HY-P73444A

	TNF-alpha/TNFSF2 Protein, Cynomolgus (N-His) Tumor necrosis factor; Cachectin; TNF-Alpha; Tnf; Tnfa; Tnfsf2; ICD1	Cynomolgus	E. coli
	TNF-alpha/TNFSF2 protein binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It induces tumor cell death, fever, cachexia, cell proliferation, and cell differentiation. It also causes insulin resistance and GKAP42 protein degradation in adipocytes. Additionally, it plays a role in angiogenesis, osteoclastogenesis, and IL12 production in dendritic cells. TNF-alpha/TNFSF2 Protein, Cynomolgus (N-His) is the recombinant cynomolgus-derived TNF-alpha/TNFSF2 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P70115

	EDAR Protein, Mouse (HEK293, Fc) rMuTumor necrosis factor receptor superfamily member EDAR/EDAR, Fc; Tumor necrosis factor receptor superfamily member EDAR; Anhidrotic ectodysplasin receptor 1; Downless; Ectodermal dysplasia receptor; Ectodysplasin-A receptor	Mouse	HEK293
	EDAR protein is a receptor for the EDA isoform TAA, which, unlike TA-2, may activate the NF-kappa-B and JNK pathways, indicating its involvement in immune signaling. In addition, EDAR may cause caspase-independent cell death. EDAR Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived EDAR protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P70805

	TNFRSF11B/OPG Protein, Human (HEK293, His) Tumor necrosis factor Receptor Superfamily Member 11B; Osteoclastogenesis Inhibitory factor; Osteoprotegerin; TNFRSF11B; OCIF; OPG	Human	HEK293
	Osteoprotegerin (OPG), a TNF receptor superfamily, is expressed in many tissues including heart, kidney, liver, spleen, and bone marrow. Osteoprotegerin has osteoprotective effect and is critical in bone remodeling. Osteoprotegerin can bind to RANKL and inhibit the binding between TNFSF11 and RANKL, thereby neutralizing the RANKL function in osteoclastogenesis. OPG is also involved in multiple biological processes of cancers. TNFRSF11B/OPG Protein, Human (HEK293, His) is a recombinant human TNFRSF11B/OPG (E22-L401) with C-terminal 6*His tag, which is produced in HEK293 cell.

HY-P71017

	TNFRSF11B/OPG Protein, Mouse (HEK293, His) 1 Publications Verification Tumor necrosis factor receptor superfamily member 11B; Osteoclastogenesis inhibitory factor; Osteoprotegerin; Tnfrsf11b; Ocif; Opg	Mouse	HEK293
	Osteoprotegerin (OPG), a TNF receptor superfamily, is expressed in many tissues including heart, kidney, liver, spleen, and bone marrow. Osteoprotegerin has osteoprotective effect and is critical in bone remodeling. Osteoprotegerin can bind to RANKL and inhibit the binding between TNFSF11 and RANKL, thereby neutralizing the RANKL function in osteoclastogenesis. OPG is also involved in multiple biological processes of cancers. TNFRSF11B/OPG Protein, Mouse (HEK293, His) is a recombinant mouse TNFRSF11B/OPG (E22-L401) with C-terminal 10*His tag, which is produced in HEK293 cell.

HY-P70808

	CD40L/CD154/TRAP Protein, Mouse (HEK293, His) CD40 Ligand; CD40LG; HIGM1; T-B cell-activating molecule; T-BAM; TNFSF5; Tumor necrosis factor (ligand) superfamily member 5; Tumor necrosis factor ligand superfamily member 5	Mouse	HEK293
	CD40L (CD154; TRAP) is a ligand to CD40/TNFRSF5, acts function by generating a costimulatory signal that up-regulates IL-4 synthesis. CD40L is specifically expressed on activated CD4+ T-lymphocytes and involves in activation of NF-κB/MAPK pathway. CD40L also involves in B cell differentiation, maturation, and apoptosis. CD40L in mouse, cleaved into 2 chains of membrane form (1-260 a.a.) and soluble form (112-260 a.a.) which serves as a ligand for integrins (ITGA5:ITGB1 and ITGAV:ITGB3). CD40L/CD154/TRAP Protein, Mouse (HEK293, His) has a total length of 149 amino acids (M112-L260), is expressed in HEK392 cells with N-terminal 6*His-tag.

HY-P7053

	TNFRSF11B/OPG Protein, Human (CHO, Fc) rHuOPG; Tumor necrosis factor receptor superfamily member 11B; TNFRSF11B; OCIF	Human	CHO
	Osteoprotegerin (OPG), a TNF receptor superfamily, is expressed in many tissues including heart, kidney, liver, spleen, and bone marrow. Osteoprotegerin has osteoprotective effect and is critical in bone remodeling. Osteoprotegerin can bind to RANKL and inhibit the binding between TNFSF11 and RANKL, thereby neutralizing the RANKL function in osteoclastogenesis. OPG is also involved in multiple biological processes of cancers. TNFRSF11B/OPG Protein, Human (CHO, Fc) is a recombinant human TNFRSF11B/OPG (E22-L201) with C-terminal hFc tag, which is produced in CHO cell.

HY-P71687

	RANK/TNFRSF11A Protein, Human (His) CD265; FEO; TRANCER; Tumor necrosis factor receptor superfamily member 11a NFKB activator	Human	E. coli
	RANK (TNFRSF11A) is a receptor activator of nuclear factor κB (NF-κB), which is involved in bone metabolism and immune system function. RANK is mainly expressed by osteoblasts/stromal cells, and is associated with the formation of giant cell tumor of bone (GCTBs) . RANK combined with RANKL ligand activated the RANKL/RANK/ OPG system to regulate bone resorption . RANKL/RANK is also a regulator of dendritic cell (DC)-T cell interaction, which is associated with mammary epithelial formation and central nervous system thermoregulation in lactating female . RANK/TNFRSF11A Protein, Human (His) produced by HEK293 cells with N-terminal His-tag.

HY-P72631

	GITR Protein, Mouse (HEK293, Fc-His) Tumor necrosis factor receptor superfamily member 18; CD357; Tnfrsf18; GITR	Mouse	HEK293
	GITR (TNFRSF18) is a member of the TNFR superfamily. GITR promotes T cell activation and proliferation and increases resistance to tumors and viral infections, and exacerbates autoimmune diseases and inflammation processes. GITR Protein, Mouse (HEK293, Fc-His) is a recombinant protein with a C-terminal Fc label and a C-terminal His label, It consists of 132 amino acids (S22-H153) and is produced in HEK293 cells.

HY-P73076

	GITR Protein, Human (HEK293, His) Tumor necrosis factor receptor superfamily member 18; CD357; TNFRSF18; AITR; GITR	Human	HEK293
	GITR (TNFRSF18) is a member of the TNFR superfamily. GITR promotes T cell activation and proliferation and increases resistance to tumors and viral infections, and exacerbates autoimmune diseases and inflammation processes. GITR Protein, Human (HEK293, His) is a recombinant protein with a C-terminal His label, It consists of 161 amino acids (M1-E161) and is produced in HEK293 cells.

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Cat. No.	Product Name	Chemical Structure

HY-163712S

17-Epiestriol-d5-1

17-Epiestriol-d₅-1 is the deuterium labeled 17-Epiestriol (HY-163712). 17-Epiestriol is an estrogen metabolite and a selective estrogen receptor (ER) β agonist. 17-epiestriol inhibits the mRNA and protein expression of the vascular cell adhesion molecule VCAM-1 induced by tumor necrosis factor α (TNFα). 17-epiestriol also inhibits TNFα-induced VCAM-1 expression and prevents NF-κB migration to the nucleus. 17-Epiestriol also induces the mRNA and protein expression of endothelial nitric oxide synthase .

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P80914

	TNF alpha Antibody 3 Publications Verification TNF; TNFA; TNFSF2; Tumor necrosis factor; Cachectin; TNF-alpha; Tumor necrosis factor ligand superfamily member 2; TNF-a	WB, IHC-F, IHC-P, ICC/IF, ELISA	Human, Mouse, Rat
	TNF alpha Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 26 kDa, targeting to TNF alpha. It can be used for WB,IHC-F,IHC-P,ICC/IF,ELISA assays with tag free, in the background of Human, Mouse, Rat.

HY-P86413

	TNF α Antibody (YA6105) TNF; TNFA; TNFSF2; Tumor necrosis factor; Cachectin; TNF-alpha; Tumor necrosis factor ligand superfamily member 2; TNF-a	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	TNF α Antibody (YA6105) is a rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TNF-α. It can be applicated for WB, IHC-P, ICC/IF, IP, ELISA assays, in the background of human, mouse, rat.

HY-P85305

	OPG Antibody (YA4997) TNFRSF11B; OCIF; OPG; Tumor necrosis factor receptor superfamily member 11B; Osteoclastogenesis inhibitory factor; Osteoprotegerin	WB, ICC/IF, FC, ELISA	Human
	OPG Antibody (YA4997) is a mouse-derived and non-conjugated monoclonal antibody, targeting to OPG. It can be applicated for WB, ICC/IF, FC, ELISA assays, in the background of human.

HY-P85306

	OPG Antibody (YA4998) TNFRSF11B; OCIF; OPG; Tumor necrosis factor receptor superfamily member 11B; Osteoclastogenesis inhibitory factor; Osteoprotegerin	WB, IHC-P, ICC/IF, ELISA	Human
	OPG Antibody (YA4998) is a mouse-derived and non-conjugated monoclonal antibody, targeting to OPG. It can be applicated for WB, IHC-P, ICC/IF, ELISA assays, in the background of human.

HY-P81756

	BCMA Antibody (YA1501) TNFRSF17; BCM; BCMA; Tumor necrosis factor receptor superfamily member 17; B-cell maturation protein; CD269	FC, ELISA	Human
	BCMA Antibody (YA1501) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1501), targeting BCMA. BCMA Antibody (YA1501) can be used for FC, ELISA experiment in human background.

HY-P82428

	Pentraxin 3 Antibody (YA2173) PTX3; TNFAIP5; TSG14; Pentraxin-related protein PTX3; Pentaxin-related protein PTX3; Tumor necrosis factor alpha-induced protein 5; TNF alpha-induced protein 5; Tumor necrosis factor-inducible gene 14 protein; TSG-14	WB, FC	Human, Mouse
	Pentraxin 3 Antibody (YA2173) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2173), targeting Pentraxin 3, with a predicted molecular weight of 42 kDa (observed band size: 42 kDa). Pentraxin 3 Antibody (YA2173) can be used for WB, FC experiment in human, mouse background.

HY-P82571

	4 1BBL Antibody (YA2316) TNFSF9; Tumor necrosis factor ligand superfamily member 9; 4-1BB ligand; 4-1BBL	WB, IP	Human
	4 1BBL Antibody (YA2316) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2316), targeting 4 1BBL, with a predicted molecular weight of 27 kDa (observed band size: 25-32 kDa). 4 1BBL Antibody (YA2316) can be used for WB, IP experiment in human background.

HY-P81584

	4-1BB Ligand Antibody (YA1329) TNFSF9; Tumor necrosis factor ligand superfamily member 9; 4-1BB ligand; 4-1BBL	FC, ELISA	Human
	4-1BB Ligand Antibody (YA1329) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1329), targeting 4-1BB Ligand. 4-1BB Ligand Antibody (YA1329) can be used for FC, ELISA experiment in human background.

HY-P84953

	4-1BBL/CD137L Antibody (YA4645) TNFSF9; Tumor necrosis factor ligand superfamily member 9; 4-1BB ligand; 4-1BBL
	4-1BBL/CD137L Antibody (YA4645) is a non-conjugated antibody, targeting to 4-1BBL/CD137L.

HY-P84980

	CD269/BCMA Antibody (YA4672) TNFRSF17; BCM; BCMA; Tumor necrosis factor receptor superfamily member 17; B-cell maturation protein; CD269; CD269 nanobody; BCMA nanobody	FC, ELISA	Human
	CD269/BCMA Antibody (YA4672) is a mouse-derived and non-conjugated monoclonal antibody, targeting to CD269/BCMA. It can be applicated for FC, ELISA assays, in the background of human.

HY-P81762

	TNFSF12 Antibody (YA1507) TNFSF12; APO3L; DR3LG; Tumor necrosis factor ligand superfamily member 12; APO3 ligand; TNF-related weak inducer of apoptosis; TWEAK	FC, ELISA	Human
	TNFSF12 Antibody (YA1507) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1507), targeting TNFSF12. TNFSF12 Antibody (YA1507) can be used for FC, ELISA experiment in human background.

HY-P85296

	NGFR p75 Antibody (YA4988) NGFR; TNFRSF16; Tumor necrosis factor receptor superfamily member 16; Gp80-LNGFR; Low affinity neurotrophin receptor p75NTR; Low-affinity nerve growth factor receptor; NGF receptor; p75 ICD; CD antigen CD271	WB, ICC/IF, FC, ELISA	Human
	NGFR p75 Antibody (YA4988) is a mouse-derived and non-conjugated monoclonal antibody, targeting to NGFR p75. It can be applicated for WB, ICC/IF, FC, ELISA assays, in the background of human.

HY-P86549

	Fas Antibody (YA6241) FAS; APT1; FAS1; TNFRSF6; Tumor necrosis factor receptor superfamily member 6; Apo-1 antigen; Apoptosis-mediating surface antigen FAS; FASLG receptor; CD antigen CD95	WB, IHC-P, ICC/IF, IP, ELISA	Human
	Fas Antibody (YA6241) is a rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Fas. It can be applicated for WB, IHC-P, ICC/IF, IP, ELISA assays, in the background of human.

HY-P81500

	p75 NGF Receptor Antibody (YA1245) NGFR; TNFRSF16; Tumor necrosis factor receptor superfamily member 16; Gp80-LNGFR; Low affinity neurotrophin receptor p75NTR; Low-affinity nerve growth factor receptor; NGF receptor; p75 ICD; CD antigen CD271	IHC-P	Human
	p75 NGF Receptor Antibody (YA1245) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1245), targeting p75 NGF Receptor. p75 NGF Receptor Antibody (YA1245) can be used for IHC-P experiment in human background.

HY-P81124

	RANKL/CD254 Antibody OPGL; CD254; hRANKL2; ODF; OPGL; Osteoclast differentiation factor; Osteoprotegerin ligand; RANKL; Receptor activator of nuclear factor kappa B ligand; sOdf; SOFA; TNF related activation induced cytokine; TNFSF 11; TNFSF11; TRANCE; Tumor necrosis factor ligand superfamily member 11; Osteoprotegerin Ligand; TNF11_HUMAN.	WB, IHC-P, ELISA	Human, Mouse, Rat
	RANKL/CD254 Antibody is an unconjugated, approximately 35 kDa, rabbit-derived, anti-RANKL/CD254 polyclonal antibody. RANKL/CD254 Antibody can be used for: WB, IHC-P, ELISA expriments in human, mouse, rat background without labeling.

HY-P85090

	CD40 Antibody (YA4782) CD40; TNFRSF5; Tumor necrosis factor receptor superfamily member 5; B-cell surface antigen CD40; Bp50; CD40L receptor; CDw40; CD antigen CD40	ICC/IF, ELISA	Human
	CD40 Antibody (YA4782) is a mouse-derived and non-conjugated monoclonal antibody, targeting to CD40. It can be applicated for ICC/IF, ELISA assays, in the background of human.

HY-P85832

	CD40 Antibody (YA5524) CD40; TNFRSF5; Tumor necrosis factor receptor superfamily member 5; B-cell surface antigen CD40; Bp50; CD40L receptor; CDw40; CD antigen CD40	FC, ELISA	Human
	CD40 Antibody (YA5524) is a mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD40. It can be applicated for FC, ELISA assays, in the background of human.

HY-P81759

	OX40 Antibody (YA1504) TNFRSF4; TXGP1L; Tumor necrosis factor receptor superfamily member 4; ACT35 antigen; OX40L receptor; TAX transcriptionally-activated glycoprotein 1 receptor; CD antigen CD134	FC, ELISA	Human
	OX40 Antibody (YA1504) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1504), targeting OX40. OX40 Antibody (YA1504) can be used for FC, ELISA experiment in human background.

HY-P81730

	OX40L Antibody (YA1475) TNFSF4; TXGP1; Tumor necrosis factor ligand superfamily member 4; Glycoprotein Gp34; OX40 ligand; OX40L; TAX transcriptionally-activated glycoprotein 1; CD antigen CD252	FC, ELISA	Human
	OX40L Antibody (YA1475) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1475), targeting OX40L. OX40L Antibody (YA1475) can be used for FC, ELISA experiment in human background.

HY-P85005

	CD70 Antibody (YA4697) CD70; CD27L; CD27LG; TNFSF7; CD70 antigen; CD27 ligand; CD27-L; Tumor necrosis factor ligand superfamily member 7; CD antigen CD70; CD70 nanobody	ELISA, FC	Human
	CD70 Antibody (YA4697) is a mouse-derived and non-conjugated monoclonal antibody, targeting to CD70. It can be applicated for ELISA, FC assays, in the background of human.

HY-P81765

	BAFF Antibody (YA1510) TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; Tumor necrosis factor ligand superfamily member 13B; B lymphocyte stimulator; BLyS; B-cell-activating factor; BAFF; Dendritic cell-derived TNF-like molecule; TNF- and APOL-related leukocyte expressed ligand 1; TALL-1; CD257	FC, ELISA	Human
	BAFF Antibody (YA1510) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1510), targeting BAFF. BAFF Antibody (YA1510) can be used for FC, ELISA experiment in human background.

HY-P85577

	DR5 Antibody (YA5269) Fas like protein; Apoptosis inducing protein TRICK2A/2B; Apoptosis inducing receptor TRAIL R2; CD 262; CD262; CD262 antigen; Cytotoxic TRAIL receptor 2; Death domain containing receptor for TRAIL/Apo 2L; Death domain containing receptor for TRAIL/Apo2L; Death receptor 5; DR 5; DR5; Fas like protein precursor; KILLER; KILLER/DR5; OTTHUMP00000123492; OTTHUMP00000123493; p53 regulated DNA damage inducible cell death receptor; killer; p53 regulated DNA damage inducible cell death receptor; killer; TNF related apoptosis inducing ligand receptor 2; TNF related apoptosis inducing ligand receptor 2; TNF-related apoptosis-inducing ligand receptor 2; TNFRSF10B; TR10B_HUMAN; TRAIL R2; TRAIL receptor 2; TRAIL-R2; TRAILR2; TRANCER; TRICK2; TRICK2A; TRICK2B; TRICKB; Tumor necrosis factor receptor like protein ZTNFR9; Tumor necrosis factor receptor like protein ZTNFR9; Tumor necrosis factor receptor superfamily member 10b; Tumor necrosis factor receptor superfamily, member 10b; ZTNFR9.	WB, ICC	Human, Mouse
	DR5 Antibody (YA5269) is a mouse-derived and non-conjugated monoclonal antibody, targeting to DR5. It can be applicated for WB, ICC assays, in the background of human, mouse.

HY-P82486

	TNFAIP3 Antibody (YA2231) TNFAIP3; OTUD7C; Tumor necrosis factor alpha-induced protein 3; TNF alpha-induced protein 3; OTU domain-containing protein 7C; Putative DNA-binding protein A20; Zinc finger protein A20	WB, IHC-F, IHC-P, ICC/IF	Human
	TNFAIP3 Antibody (YA2231) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2231), targeting TNFAIP3, with a predicted molecular weight of 90 kDa (observed band size: 90 kDa). TNFAIP3 Antibody (YA2231) can be used for WB, IHC-F, IHC-P, ICC/IF experiment in human background.

HY-P84962

	CD137/4-1BB Antibody (YA4654) TNFRSF9; CD137; ILA; Tumor necrosis factor receptor superfamily member 9; 4-1BB ligand receptor; CDw137; T-cell antigen 4-1BB homolog; T-cell antigen ILA; CD antigen CD137
	CD137/4-1BB Antibody (YA4654) is a non-conjugated antibody, targeting to CD137/4-1BB.

HY-P81123

	OPG Antibody (YA3535) MGC29565 antibody; OCIF antibody; OPG antibody; Osteoclastogenesis inhibitory factor antibody; Osteoprotegerin antibody; PDB5 antibody; TNF receptor superfamily member 11b antibody; TNFRSF 11B antibody; TNFRSF11B antibody; TR 1 antibody; TR1 antibody; TR11B_HUMAN antibody; Tumor necrosis factor receptor superfamily member 11B antibody;	WB, IHC-P, ICC/IF	Human, Mouse, Rat
	OPG Antibody is an unconjugated, approximately 46 kDa,mouse-derived, anti-OPG monoclonal antibody. OPG Antibody can be used for: WB, IF-Cell, IHC-P expriments in human, mouse, rat background without labeling.

HY-P82843

	DcR2 Antibody (YA2588) TNFRSF10D; DCR2; TRAILR4; TRUNDD; Tumor necrosis factor receptor superfamily member 10D; Decoy receptor 2; DcR2; TNF-related apoptosis-inducing ligand receptor 4; TRAIL receptor 4; TRAIL-R4; TRAIL receptor with a truncated death domain; CD	WB, IHC-P, ICC/IF	Human
	DcR2 Antibody (YA2588) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2588), targeting DcR2, with a predicted molecular weight of 42 kDa (observed band size: 36 kDa). DcR2 Antibody (YA2588) can be used for WB, IHC-P, ICC/IF experiment in human background.

HY-P83029

	p75 NGF Receptor Antibody (YA2774) CD271 antibody; CD271 antigen antibody; Gp80 LNGFR antibody; Gp80-LNGFR antibody; Low affinity nerve growth factor receptor antibody; Low affinity neurotrophin receptor p75NTR antibody; Low-affinity nerve growth factor receptor antibody; Nerve growth factor receptor antibody; Nerve growth factor receptor TNFR superfamily member 16 antibody; NGF receptor antibody; Ngfr antibody; p75 ICD antibody; p75 Neurotrophin receptor antibody; p75 NTR antibody; p75(NTR) antibody; p75NTR antibody; TNFR Superfamily Member 16 antibody; TNFRSF16 antibody; TNR16_HUMAN antibody; Tumor necrosis factor receptor superfamily member 16 antibody	WB, IHC-P, ICC/IF, IP	Human, Mouse, Rat
	NGFR Antibody (YA2774) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2774), targeting NGFR, with a predicted molecular weight of 45 kDa (observed band size: 75 kDa). NGFR Antibody (YA2774) can be used for WB, IHC-P, ICC/IF, IP experiment in human, mouse, rat background.

HY-P84961

	CD134 Antibody (YA4653) ACT 35 antibody; ATC35 antigen antibody; CD134 antibody; IMD16 antibody; Lymphoid activation antigene ACT35 antibody; OX40 antibody; OX40L receptor antibody; TAX transcriptionally activated glycoprotein 1 receptor antibody; TNF receptor superfamily member 4 antibody; TNFRSF 4 antibody; TNR4_HUMAN antibody; Tumor necrosis factor receptor superfamily member 4 antibody; Txgp 1l antibody; Txgp1 antibody	WB, ICC/IF, IP, FC	Human
	CD134 Antibody (YA4653) is a non-conjugated antibody, targeting to CD134.

HY-P84981

	CD27 Antibody (YA4673) CD 27 antibody; CD27 antibody; CD27 antigen antibody; CD27 molecule antibody; CD27_HUMAN antibody; CD27L receptor antibody; LPFS2 antibody; MGC20393 antibody; OTTHUMP00000238557 antibody; S152 antibody; T cell activation antigen CD27 antibody; T cell antivation antigen S152 antibody; T-cell activation antigen CD27 antibody; T14 antibody; TNFRSF 7 antibody; TNFRSF7 antibody; TNFSF7 antibody; Tp 55 antibody; Tp55 antibody; Tumor necrosis factor receptor superfamily member 7 antibody; CD27 nanobody	FC, ELISA	Human
	CD27 Antibody (YA4673) is a mouse-derived and non-conjugated monoclonal antibody, targeting to CD27. It can be applicated for FC, ELISA assays, in the background of human.

HY-P85859

	CD27 Antibody (YA5551) CD 27 antibody; CD27 antibody; CD27 antigen antibody; CD27 molecule antibody; CD27_HUMAN antibody; CD27L receptor antibody; LPFS2 antibody; MGC20393 antibody; OTTHUMP00000238557 antibody; S152 antibody; T cell activation antigen CD27 antibody; T cell antivation antigen S152 antibody; T-cell activation antigen CD27 antibody; T14 antibody; TNFRSF 7 antibody; TNFRSF7 antibody; TNFSF7 antibody; Tp 55 antibody; Tp55 antibody; Tumor necrosis factor receptor superfamily member 7 antibody; CD27 nanobody;	FC, ELISA	Human
	CD27 Antibody (YA5551) is a mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD27. It can be applicated for FC, ELISA assays, in the background of human.

HY-P85515

	FAS(C-term) Antibody (YA5207) ALPS 1A; ALPS1A; APO 1; Apo 1 antigen; APO 1 cell surface antigen; Apo-1 antigen; APO1; Apo1 antigen; APO1 cell surface antigen; Apoptosis antigen 1; Apoptosis mediating surface antigen FAS; Apoptosis-mediating surface antigen FAS; APT 1; APT1; CD 95; CD 95 antigen; CD95; CD95 antigen; Delta Fas; Delta Fas/APO 1/CD95; Delta Fas/APO1/CD95; Fas; TNF receptor superfamily, member 6; FAS 1; FAS 827dupA; Fas AMA; FAS; FAS Antigen; Fas cell surface death receptor; FAS1; FASLG receptor; FASTM; sFAS; Surface antigen APO1; TNF receptor superfamily, member 6; TNFRSF 6; TNFRSF6; TNR6_HUMAN; Tumor necrosis factor receptor superfamily member 6.	WB	Human
	FAS(C-term) Antibody (YA5207) is a mouse-derived and non-conjugated monoclonal antibody, targeting to FAS (C-term). It can be applicated for WB assays, in the background of human.