2. Recombinant Proteins
  3. Cytokines and Growth Factors
  4. TNF Superfamily
  5. TNF Receptor Superfamily
  6. Decoy Receptor 3
  7. DcR3/TNFRSF6B Protein, Human (HEK293, hFc)

DcR3/TNFRSF6B Protein, Human (HEK293, hFc) is the recombinant human-derived DcR3/TNFRSF6B protein, expressed by HEK293, with C-hFc tag.

For research use only. We do not sell to patients.

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Description

DcR3/TNFRSF6B Protein, Human (HEK293, hFc) is the recombinant human-derived DcR3/TNFRSF6B protein, expressed by HEK293, with C-hFc tag.
Background

DcR3/TNFRSF6B is a decoy receptor capable of neutralizing cytotoxic ligands TNFS14/LIGHT, TNFSF15, and TNFSF6/FASL, thereby providing anti-apoptotic protection.
Species

Human
Source

HEK293
Tag

C-hFc
Accession

O95407 (V30-H300)
Gene ID

8771
Molecular Construction
N-term
TNF6B (V30-H300)
Accession # O95407
hFc
C-term
Synonyms
Tumor necrosis factor receptor superfamily member 6B; Decoy receptor 3; TNFRSF6B; DCR3; TR6
Predicted Molecular Mass
56.2 kDa
Molecular Weight

Approximately 60-65 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.
Glycosylation
Yes
Purity

Greater than 90% as determined by reducing SDS-PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

DcR3/TNFRSF6B Protein, Human (HEK293, hFc) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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