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serum

" in MedChemExpress (MCE) Product Catalog:

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119

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Oligonucleotides

Targets Recommended: SGK

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P3206A

Serum thymic factor acetate Thymulin acetate; Thymic factor acetate	ERK	Neurological Disease Inflammation/Immunology Endocrinology
Serum thymic factor acetate (Thymulin acetate) is the acetate salt form of Serum thymic factor (HY-P3206). Serum thymic factor acetate is a zinc-dependent immunomodulatory peptide hormone, which can be produced by the thymic epithelial cells. Serum thymic factor acetate stimulates the release of hormones from the pituitary gland, exhibits hypophysiotropic activity. Serum thymic factor acetate protects rats from Cephaloridine (HY-B2072)-induced nephrotoxicity by inhibiting ERK activation. Serum thymic factor acetate exhibits anti-diabetic, anti-inflammatory and analgesic effects. Serum thymic factor acetate can be used in research about endocrine, reproductive, neurodegenerative and inflammatory diseases .

HY-P3206

Serum thymic factor Thymulin; Thymic factor	ERK	Neurological Disease Inflammation/Immunology Endocrinology
Serum thymic factor (Thymulin) is a zinc-dependent immunomodulatory peptide hormone, which can be produced by the thymic epithelial cells. Serum thymic factor stimulates the release of hormones from the pituitary gland, exhibits hypophysiotropic activity. Serum thymic factor protects rats from Cephaloridine (HY-B2072)-induced nephrotoxicity by inhibiting ERK activation. Serum thymic factor exhibits anti-diabetic, anti-inflammatory and analgesic effects. Serum thymic factor can be used in research about endocrine, reproductive, neurodegenerative and inflammatory diseases .

HY-NP0204

*Mouse Serum* Albumin**	ELOVL Apoptosis NOD-like Receptor (NLR) Caspase Tau Protein	Neurological Disease Inflammation/Immunology
Mouse Serum Albumin is most abundant protein in plasma, which leaks into the brain parenchyma when the blood-brain barrier (BBB) is impaired. Mouse Serum Albumin induces astrocytes to A1 phenotype to remarkably increase levels of Elovl1. Mouse Serum Albumin promotes VLSFAs secretion and causes neuronal lippoapoptosis through endoplasmic reticulum stress response pathway. MSA-activated microglia triggeres remarkable tau phosphorylation at multiple sites (Ser202/Thr205) through NLRP3 inflammasome pathway. Mouse Serum Albumin decreases the spatial learning and memory abilities in mice. Mouse Serum Albumin can be used for the study of neurodegenerative diseases like Alzheimer’s disease (AD) and frontotemporal dementia (FTD) .

HY-NP001

*Cationic Bovine Serum* Albumin** 1 Publications Verification CBSA	Biochemical Assay Reagents	Neurological Disease
Cationic Bovine Serum Albumin is a bovine serum albumin (BSA) modified with excess ethylenediamine, which has enhanced immunogenicity compared to native BSA. Positively charged primary amines block all negatively charged carboxyl groups, making Cationic Bovine Serum Albumin a cationic protein. Cationic Bovine Serum Albumin has remarkable neuroprotective effects on ischemic stroke when in combination with Tanshinone IIA (HY-N0135) .

HY-NP002E

*Porcine Serum* Albumin**	Biochemical Assay Reagents	Others
Porcine Serum Albumin is a serum albumin protein that contains a flexible C-terminal region.

HY-P2352

Fetuin, Fetal Bovine Serum 4 Publications Verification	Biochemical Assay Reagents	Metabolic Disease
Fetuin, Fetal Bovine Serum is a liver-secreted 64 kDa plasma glycoprotein isolated from fetal bovine serum. Fetuin, Fetal Bovine Serum inhibits trypsin activity and promote cellular attachment, growth, and differentiation .

HY-NP002D

*Bovine Serum* Albumin (Biotinylated)**	Biochemical Assay Reagents	Others
Bovine Serum Albumin (Biotinylated) is a biotinylated bovine serum albumin that selectively binds to different vascular subsets in lymphoid tissue. Serum albumin is a multifunctional protein with extraordinary ligand binding capacity, making it a transporter molecule for a diverse range of metabolites, drugs, nutrients, metals and other molecules .

HY-D1287

Serum CG probe 2	Fluorescent Dye	Inflammation/Immunology
Serum CG probe 2 (formula (15)) is a compound for determining serum cholyglycine .

HY-D1286

Serum CG probe 1	Fluorescent Dye	Inflammation/Immunology
Serum CG probe 1 (formula (9)) is a compound for determining serum cholyglycine .

HY-NP0208

*Chicken Serum* Transferrin**	Transferrin Receptor	Inflammation/Immunology
Chicken Serum Transferrin is a major serum protein in chicken serum. Chicken Serum Transferrin is primarily responsible for transporting iron .

HY-NP002H

*Porcine Serum* Albumin (globulin free)**	Biochemical Assay Reagents	Others
Porcine Serum Albumin (globulin free) is a serum albumin protein that contains a flexible C-terminal region.

HY-NP002B

*Rabbit Serum* Albumin**	Biochemical Assay Reagents	Others
Rabbit Serum Albumin is a plasma protein derived from rabbits. Serum albumin is a multifunctional protein with extraordinary ligand binding capacity, making it a transporter molecule for a diverse range of metabolites, drugs, nutrients, metals and other molecules .

HY-NP002A

*Goat Serum* Albumin**	Biochemical Assay Reagents	Others
Goat Serum Albumin is a plasma protein derived from goats. Serum albumin is a multifunctional protein with extraordinary ligand binding capacity, making it a transporter molecule for a diverse range of metabolites, drugs, nutrients, metals and other molecules .

HY-NP002L

*Canine Serum* Albumin**	Biochemical Assay Reagents	Others
Canine Serum Albumin is a plasma protein derived from canine. Serum albumin is a multifunctional protein with extraordinary ligand binding capacity, making it a transporter molecule for a diverse range of metabolites, drugs, nutrients, metals and other molecules .

HY-NP002K

*Rat Serum* Albumin**	Biochemical Assay Reagents	Others
Rat Serum Albumin is a plasma protein derived from rat. Serum albumin is a multifunctional protein with extraordinary ligand binding capacity, making it a transporter molecule for a diverse range of metabolites, drugs, nutrients, metals and other molecules .

HY-NP0215

*Chicken Serum* Albumin**	Biochemical Assay Reagents	Others
Chicken Serum Albumin is a plasma protein derived from chicken. Serum albumin is a multifunctional protein with extraordinary ligand binding capacity, making it a transporter molecule for a diverse range of metabolites, drugs, nutrients, metals and other molecules .

HY-NP002N

*Pigeon Serum* Albumin**	Biochemical Assay Reagents	Others
Pigeon Serum Albumin is a plasma protein derived from pigeon. Serum albumin is a multifunctional protein with extraordinary ligand binding capacity, making it a transporter molecule for a diverse range of metabolites, drugs, nutrients, metals and other molecules .

HY-NP002I

*Sheep Serum* Albumin**	Biochemical Assay Reagents	Others
Sheep Serum Albumin is a plasma protein derived from sheep. Serum albumin is a multifunctional protein with extraordinary ligand binding capacity, making it a transporter molecule for a diverse range of metabolites, drugs, nutrients, metals and other molecules .

HY-NP002J

*Horse Serum* Albumin**	Biochemical Assay Reagents	Others
Horse Serum Albumin is a plasma protein derived from horse. Serum albumin is a multifunctional protein with extraordinary ligand binding capacity, making it a transporter molecule for a diverse range of metabolites, drugs, nutrients, metals and other molecules .

HY-150097

*Recombinant Human Serum* Albumin(rHSA)**	Biochemical Assay Reagents	Others
Recombinant Human Serum Albumin (rHSA) is an active compound and possesses an identical conformation to plasma derived HSA. Recombinant Human Serum Albumin (rHSA) has no difference between rHSA and plasma derived HSA. The main physiological function of Recombinant Human Serum Albumin (rHSA) is to regulate plasma pH and maintain plasma osmotic pressure .

HY-NP002M

*Guinea Pig serum* albumin**	Biochemical Assay Reagents	Others
Guinea Pig Serum Albumin is a plasma protein derived from guinea pig. Serum albumin is a multifunctional protein with extraordinary ligand binding capacity, making it a transporter molecule for a diverse range of metabolites, drugs, nutrients, metals and other molecules .

HY-P1956

*Human serum* albumin** 2 Publications Verification HSA	NF-κB NO Synthase	Cardiovascular Disease Inflammation/Immunology Cancer
Human serum albumin (HSA) is the most abundant protein in plasma and is a major determinant of plasma oncotic pressure. Human serum albumin exhibits antioxidant, anticoagulant, anti-inflammatory, anti-platelet aggregation activities as well as colloid osmotic action. Human serum albumin can block the inhibitory effect of GML on human T cells, providing protective function for T cells. Human serum albumin is also associated with cardiovascular diseases and can partially prevent the LPS (HY-D1056) induced oxidative stress, as well as the upregulation of NF-κB, NF-κB, and peroxynitrite (ONOO ⁻) in the vascular wall, contributing to the reduction of blood pressure .

HY-D0842

*Bovine Serum* Albumin** Maximum Cited Publications 44 Publications Verification Albumin bovine serum; BSA	Biochemical Assay Reagents	Inflammation/Immunology
Bovine Serum Albumin (BSA) is a 583-residue protein consisting of three homologous all-α domains, organized in a heart-shaped structure. BSA is a globular protein that is used in numerous biochemical applications.

HY-NP002C

*Rabbit Serum* Albumin (globulin free)**	Biochemical Assay Reagents	Others
Rabbit Serum Albumin (globulin free) is a plasma protein derived from rabbits. Serum albumin is a multifunctional protein with extraordinary ligand binding capacity, making it a transporter molecule for a diverse range of metabolites, drugs, nutrients, metals and other molecules .

HY-154818

*Bovine Serum* Albumin, Acetylated** Ac-BSA	Biochemical Assay Reagents	Others
Bovine Serum Albumin, Acetylated (Ac-BSA) is a polypeptide of known structure with strong antigenicity. Bovine Serum Albumin, Acetylated produced a significant immune response, validating the accuracy and reliability of the experimental method. Bovine Serum Albumin, Acetylated can be used as a positive control substance in ELISA or WB experiments, and can be used in experiments with acetylated lysine monoclonal or polyclonal antibodies. Bovine Serum Albumin, Acetylated also improves encapsulation efficiency at low concentrations of PLGA, a polymer for biopharmaceutical delivery with biocompatibility, degradability, and controlled release properties .

HY-NP204

*Human Serum* Albumin-AF750**	Biochemical Assay Reagents Fluorescent Dye	Cardiovascular Disease Inflammation/Immunology
Human Serum Albumin-AF750 is a biochemical reagent conjugated to fluorescein AF750 (Ex=752 nM; Em=780 nm). Human Serum Albumin-AF750 can be used to label or detect specific antigens, molecules or cellular structures .

HY-P2798

Cholinesterase, Horse serum EC 3.1.1.8; BCHE, Horse serum	Cholinesterase (ChE)	Neurological Disease
Cholinesterase, Horse serum infers to acetylcholinesterase (AChE) and butyryl cholinesterase (BChE). AChE and BChE catalyze the hydrolysis of 6-MAM to morphine .

HY-D0842A

*Bovine Serum* Albumin (Low Endotoxin,Fatty acid free)** Albumin bovine serum (Low Endotoxin,Fatty acid free); BSA (Low Endotoxin,Fatty acid free)	Biochemical Assay Reagents Nucleoside Antimetabolite/Analog	Inflammation/Immunology
Bovine Serum Albumin (Low Endotoxin,Fatty acid free) (BSA) is a 583 amino acid globular protein and oligonucleotide binding protein composed of three homologous full α domains. Bovine Serum Albumin (Low Endotoxin,Fatty acid free) (BSA) blocks the overall binding of oligonucleotides to cells. Bovine Serum Albumin (Low Endotoxin,Fatty acid free) (BSA) regulates the development of hamster embryos and induces arthritis .

HY-NP051

*Bovine Serum* Albumin-FITC**	Biochemical Assay Reagents	Others
Bovine Sermu Albumin-FITC is a bovine serum albumin conjugated to FITC (Ex=495 nm; Em=525 nm). Bovine Sermu Albumin-FITC can be used as a fluorescent marker to label or detect specific antigens, molecules or cellular structures .

HY-N10627

NA2 Glycan	Endogenous Metabolite	Others
NA2 Glycan is NA2 N-linked oligosaccharide. NA2 is the asialo-substructure of A2 glycan. NA2 glycan can be isolated from mammalian serum glycoproteins, such as serum IgG .

HY-N12634

*Pregnant mare serum* gonadotropin** PMSG	Endogenous Metabolite	Endocrinology
Pregnant mare serum gonadotropin (PMSG) is a gonadotropin used to promote follicular development and ovulation in animals. PMSG exerts its regulatory effects by stimulating changes in blood hormones, gonadotropins, and cytoplasmic estradiol receptors in the anterior pituitary and hypothalamus. PMSG is commonly used in livestock to improve reproductive efficiency and can also be utilized for research on estrous cycle regulation .

HY-NP141

NP-BSA 4-Hydroxy-3-nitrophenylacetyl-bovine serum albumin	Biochemical Assay Reagents	Inflammation/Immunology
NP-BSA (4-Hydroxy-3-nitrophenylacetyl-bovine serum albumin) is an antigen-adjuvant conjugate of 4-Hydroxy-3-nitrophenylacetyl (NP) conjugated to bovine serum albumin (BSA), which is an immune complex. By conjugating antigens to protein adjuvants, the production of antigen-specific antibodies in vaccine models can be enhanced. The conjugate does not affect protein folding or disrupt major epitopes, and can enhance cross-presentation and the generation of antigen-specific T cells .

HY-CP002

*Bovine Serum* Albumin, Carrier Protein**	Biochemical Assay Reagents	Others
Bovine Serum Albumin (BSA) is a 583 amino acid protein consisting of three homologous full alpha structural domains. BSA is a spherical protein essential for the transport of molecules such as fatty acids, drugs and hormones from the blood. It is used in many biochemical applications as a drug carrier for biologically active compounds. For long-term storage, recombinant protein solution should be diluted further with 0.1% BSA .

HY-141749A

Clopidogrel carboxylic acid CLPM; SR 26334	Endogenous Metabolite	Metabolic Disease
Clopidogrel carboxylic acid (CLPM) is the inactive liver metabolite of anti platelet agent, Clopidogrel (HY-15283), in human serum .

HY-P0103

Myristoyl pentapeptide-17	LPL Receptor	Metabolic Disease
Myristoyl pentapeptide-17 can stimulate eyelash growth by stimulating keratin production. Myristoyl pentapeptide-17 promotes the delivery of key ingredients in the serum, such as the growth factors and lysophosphatidic acid .

HY-P99478

Bifarcept	IFNAR	Inflammation/Immunology
Bifarcept is an interferon receptor type I (IFN-RI) fusion protein. Bifarcept can bind interferon receptors and prolong its serum half-life .

HY-D0112

7-Hydroxycoumarin-4-acetic acid	Fluorescent Dye	Others
7-Hydroxycoumarin-4-acetic acid, a pH-indicator dye, is covalently bound to bovine serum albumin (BSA) at the positions of reactive amino groups (λ_max=326 nm) .

HY-119320

Ethimidine Aethimidinum	Biochemical Assay Reagents	Cancer
Ethimidine (Aethimidinum) can reduce the blood serum free SH (sulfhydryl) in in rats previously transplanted with sarcoma or carcinoma cells .

HY-147094

vc-PABC-DM1	ADC Linker	Cancer
vc-PABC-DM1 used to synthesize an ADC molecule based on utilize disulfide linker. vc-PABC-DM1 can be used to explore serum stability .

HY-P99796

Ozoralizumab ATN-103; PF-5230896	TNF Receptor	Inflammation/Immunology
Ozoralizumab (ATN-103) is an anti-TNFα humanized antibody. Ozoralizumab is a humanized trivalent nanobody compound that consists of two anti-human TNFα nanobodies and an anti-human serum albumin (HSA) nanobody. Ozoralizumab can be used in research of arthritis .

HY-143712

Allolithocholic acid 1 Publications Verification	Endogenous Metabolite	Metabolic Disease
Allolithocholic acid is a steroid acid could found in normal serum and feces. Allolithocholic acid facilitates excretion, absorption, and transport of fats and sterols in the intestine and liver .

HY-N8773

3,5,7-Trihydroxychromone	Others	Others
3,5,7-Trihydroxychromone is the analogue of galangin. 3,5,7-Trihydroxychromone is also the binder of bovine serum albumin. 3,5,7-Trihydroxychromone undergoes multiple antioxidant pathways .

HY-P1956A

*Human serum* albumin (Cell culture grade, Endotoxin<0.125 EU/mg)** HSA (Cell culture grade, Endotoxin<0.125 EU/mg)	NF-κB NO Synthase	Cardiovascular Disease Inflammation/Immunology
Human serum albumin (Cell culture grade, Endotoxin<0.125 EU/mg) (HSA) is the most abundant protein in plasma and is a major determinant of plasma oncotic pressure. Human serum albumin (Cell culture grade, Endotoxin<0.125 EU/mg) exhibits antioxidant, anticoagulant, anti-inflammatory, anti-platelet aggregation activities as well as colloid osmotic action. Human serum albumin (Cell culture grade, Endotoxin<0.125 EU/mg) can block the inhibitory effect of GML on human T cells, providing protective function for T cells. Human serum albumin (Cell culture grade, Endotoxin<0.125 EU/mg) is also associated with cardiovascular diseases and can partially prevent the LPS (HY-D1056) induced oxidative stress, as well as the upregulation of NF-κB, iNOS, and peroxynitrite (ONOO ⁻) in the vascular wall, contributing to the reduction of blood pressure .

HY-P99397

Sonelokimab ALX 0761; M 1095	Interleukin Related MMP	Inflammation/Immunology
Sonelokimab (ALX 0761) is a trivalent bispecific nanobody composed of camel derived humanized IL-17F antibodies, IL-17A/F antibodies, and serum albumin VHH antibodies. Sonelokimab can prolong the plasma half-life by binding to human serum albumin. Sonelokimab can be used for research on rheumatoid arthritis and psoriasis .

HY-E70362

Butyrylcholinesterase (BCHE), Horse Serum BCHE, BuChE, PCHE, pseudocholinesterase, plasma cholinesterase, Acylcholine acyl-hydrolase, Choline esterase, butyryl	Others	Others
Butyrylcholinesterase (BCHE), Horse Serum (BCHE, BuChE, PCHE, pseudocholinesterase, plasma cholinesterase, Acylcholine acyl-hydrolase, Choline esterase, butyryl) is a biological material or organic compound that can be used in life science research .

HY-176560

Raloxifene alkene	Others	Metabolic Disease Cancer
Raloxifene alkene (Compound 101) is a serum cholesterol clearance agent. Raloxifene alkene has significant anti-proliferation activity against breast adenocarcinoma cells. Raloxifene alkene effectively reduces serum cholesterol level without significant uterine weight and increase of number oieosinoohils in the stromallaver of ovarleclomized rat models. Raloxifene alkene can be used for post-menopausasyndrome, particularly osteoporosis, estrogen-dependent breast and uterine carcinoma research .

HY-P99696

Lerodalcibep LIB003	PCSK9	Cardiovascular Disease Metabolic Disease
Lerodalcibep (LIB003) is a recombinant fusion protein of a PCSK9-binding domain (adnectin) and human serum albumin. Lerodalcibep is a Lipid-lowering agent. Lerodalcibep can be used for the research of hypercholesterolemia and cardiovascular diseases .

HY-120855

CCG-100602 2 Publications Verification	Ras	Cardiovascular Disease
CCG-100602 is a specific inhibitor of myocardin-related transcription factor A/serum response factor (MRTF-A/SRF) signaling. CCG-100602 specifically block MRTF-A nuclear localization and thus inhibit the fibrogenic transcription factor SRF .

HY-132177

α-L-Fucosidase, Microorganism 1 Publications Verification EC 3.2.1.51; FUC	Endogenous Metabolite	Cancer
α-L-Fucosidase, Microorganism (EC 3.2.1.51) is an enzyme that catalyzes the chemical reaction. Serum activity of α-L-Fucosidase, Microorganism, a lysosomal enzyme present in all mammalian cells, has been proposed as a marker of hepatocellular carcinoma (HCC) .

HY-W110790

Bromocresol purple sodium	Biochemical Assay Reagents	Others
Bromocresol purple sodium is a pH indicator, whose color changes from yellow to purple when the pH increases from 5.2 to 6.8. Bromocresol purple sodium can be used for detecting yeast cells with plasma membrane damage and measuring serum albumin concentrations .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-P2352

Fetuin, Fetal Bovine Serum 4 Publications Verification	Natural Products Animals Source classification Metabolic Disease Disease Research Fields	Biochemical Assay Reagents
Fetuin, Fetal Bovine Serum is a liver-secreted 64 kDa plasma glycoprotein isolated from fetal bovine serum. Fetuin, Fetal Bovine Serum inhibits trypsin activity and promote cellular attachment, growth, and differentiation .

HY-N12634

*Pregnant mare serum* gonadotropin** PMSG	Natural Products Animals Source classification	Endogenous Metabolite
Pregnant mare serum gonadotropin (PMSG) is a gonadotropin used to promote follicular development and ovulation in animals. PMSG exerts its regulatory effects by stimulating changes in blood hormones, gonadotropins, and cytoplasmic estradiol receptors in the anterior pituitary and hypothalamus. PMSG is commonly used in livestock to improve reproductive efficiency and can also be utilized for research on estrous cycle regulation .

HY-143712

Allolithocholic acid 1 Publications Verification	Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite
Allolithocholic acid is a steroid acid could found in normal serum and feces. Allolithocholic acid facilitates excretion, absorption, and transport of fats and sterols in the intestine and liver .

HY-N8773

3,5,7-Trihydroxychromone	other families Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Phenols Polyphenols Plants Disease Research Fields	Others
3,5,7-Trihydroxychromone is the analogue of galangin. 3,5,7-Trihydroxychromone is also the binder of bovine serum albumin. 3,5,7-Trihydroxychromone undergoes multiple antioxidant pathways .

HY-W012946

2-Furoic acid Pyromucic acid	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	ATP Citrate Lyase Acyltransferase Endogenous Metabolite
2-Furoic acid (Furan-2-carboxylic acid) is an organic compound produced through furfural oxidation . 2-Furoic acid exhibits hypolipidemic effet, lowers both serum cholesterol and serum triglyceride levels in rats .

HY-113283

Homogentisic acid	Other disease Classification of Application Fields Ketones, Aldehydes, Acids Disease markers Phenols Polyphenols Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Homogentisic acid is a specific metabolite that accumulates in the urine and serum. Homogentisic acid can be used for diagnosis of alkaptonuria. Homogentisic acid is a phenolic acid .

HY-W007894

Dimethylmalonic acid 1 Publications Verification	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Dimethylmalonic acid is a short-chain dicarboxylic acid in human serum. Dimethylmalonic acid is also a volatile organic compound detected in alveolar breath .

HY-N14785

Deflectin 1a	Microorganisms Antibiotics Source classification Other Antibiotics	Antibiotic Bacterial
Deflectin 1a is an antibiotic with the activity of lysing bacteria, lysing red blood cells and inhibiting Ehrlich ascites cancer cells, and its activity can be offset by adding serum or serum albumin .

HY-W012946R

2-Furoic acid (Standard) Pyromucic acid (Standard)	Microorganisms Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Reference Standards ATP Citrate Lyase Acyltransferase Endogenous Metabolite
2-Furoic acid (Standard) is the analytical standard of 2-Furoic acid. This product is intended for research and analytical applications. 2-Furoic acid (Furan-2-carboxylic acid) is an organic compound produced through furfural oxidation . 2-Furoic acid exhibits hypolipidemic effet, lowers both serum cholesterol and serum triglyceride levels in rats .

HY-B0399A

DL-Carnitine (±)-Carnitin	Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Mitochondrial Metabolism
DL-Carnitine is a racemic mixture of L-Carnitine and D-Carnitine, regulates fatty acid transport in mitochondria, elevates serum carnitine fractions.

HY-N2341

Palmitelaidic acid 3 Publications Verification 9-trans-Hexadecenoic acid; trans-Palmitoleic acid	Animals Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Disease Research Fields	AMPK PPAR Glucokinase
Palmitelaidic acid (9-trans-Hexadecenoic acid) is the trans isomer of palmitoleic acid. Palmitoleic acid is one of the most abundant fatty acids in serum and tissue.

HY-N12811

Tenuifoliose B	Polysaccharides Source classification Polygalaceae Plants Polygala tenuifolia Willd. Saccharides	Others
Tenuifoliose B is an oligosaccharide and can be isolated from Polygala tenuifolia. Tenuifoliose B exhibits neuroprotective activity against glutamate and serum deficiency .

HY-113283R

Homogentisic acid (Standard)	Microorganisms Other disease Ketones, Aldehydes, Acids Disease markers Phenols Polyphenols Endogenous metabolite	Reference Standards Endogenous Metabolite
Homogentisic acid (Standard) is the analytical standard of Homogentisic acid. This product is intended for research and analytical applications. Homogentisic acid is a specific metabolite that accumulates in the urine and serum. Homogentisic acid can be used for diagnosis of alkaptonuria. Homogentisic acid is a phenolic acid .

HY-N5092

7-Methylcoumarin	Microorganisms Source classification Coumarins Metabolic Disease Phenylpropanoids Disease Research Fields	Reactive Oxygen Species (ROS) Cytochrome P450
7-Methylcoumarin is a coumarin derivative with potent hepatoprotective and antioxidant properties. 7-Methylcoumarin is a mechanism-based inhibitor for CYP2A6. 7-Methylcoumarin significantly decreases alanine aminotransferase (ALT), aspartate aminotransferase (AST), and serum bilirubin (TB) in rats with CCl₄-induced liver damage, whilst restoring total protein (TP) and albumin (TA) levels in serum as well as preventing oxidative stress. 7-Methylcoumarin can decline mitotic activity of A. sativum promeristem .

HY-N13079

3-Epicinobufagin	Animals Source classification Steroids	Others
3-Epicinobufagin (compound IX) can be used as an internal standard for the metabolism of Bufalin (HY-N0877), by detecting its content in serum and urine to provide feedback on the corresponding metabolic status .

HY-W007894R

Dimethylmalonic acid (Standard) Dimethylpropanedioic acid (Standard)	Microorganisms Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Reference Standards Endogenous Metabolite
Dimethylmalonic acid (Standard) is the analytical standard of Dimethylmalonic acid. This product is intended for research and analytical applications. Dimethylmalonic acid is a short-chain dicarboxylic acid in human serum. Dimethylmalonic acid is also a volatile organic compound detected in alveolar breath[1].

HY-149048

Adenosylhomocysteinase SAHH; AHCY	Infection Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite HBV
Adenosylhomocysteinase (SAHH; AHCY) is a highly conserved enzyme. Adenosylhomocysteinase reversible catalyzes S-adenosylhomocysteine (SAH) to adenosine and L-homocysteine. The serum exosomal Adenosylhomocysteinase level can be used as a prognostic biomarker in HBV-LC patients .

HY-N11551

Salvifaricin	Artemisia frigida Willd. Terpenoids Labiatae Source classification Diterpenoids Plants	Others
Salvifaricin is an orally active diterpenoid compound that can be isolated from Salvia leucantha Cav. and Salvia hispanica L.. Salvifaricin significantly reduces fasting blood glucose and serum triglyceride (TG) levels, and has anti-diabetic effect .

HY-N5092R

7-Methylcoumarin (Standard)	Microorganisms Source classification Coumarins Phenylpropanoids	Reference Standards Reactive Oxygen Species (ROS) Cytochrome P450
7-Methylcoumarin (Standard) is the analytical standard of 7-Methylcoumarin. This product is intended for research and analytical applications. 7-Methylcoumarin is a coumarin derivative with potent hepatoprotective and antioxidant properties. 7-Methylcoumarin is a mechanism-based inhibitor for CYP2A6. 7-Methylcoumarin significantly decreases alanine aminotransferase (ALT), aspartate aminotransferase (AST), and serum bilirubin (TB) in rats with CCl₄-induced liver damage, whilst restoring total protein (TP) and albumin (TA) levels in serum as well as preventing oxidative stress. 7-Methylcoumarin can decline mitotic activity of A. sativum promeristem .

HY-N14518

Pacidamycin 6	Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial
Pacidamycin 6 has inhibitory effect on Pseudomonas aeruginosa. Pacidamycin 6 also has effect on a few strains of bacteria such as suppurative staphylococcus and Escherichia coli. Serum can reduce its antibacterial activity, pH also affects its antibacterial activity .

HY-N14517

Pacidamycin 4	Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial
Pacidamycin 4 has inhibitory effect on Pseudomonas aeruginosa. Pacidamycin 4 also has effect on a few strains of bacteria such as suppurative staphylococcus and Escherichia coli. Serum can reduce its antibacterial activity, pH also affects its antibacterial activity .

HY-N14291

4-Methoxy-p-toluquinone	Quinones Microorganisms Anthraquinones Source classification	Antibiotic Bacterial Fungal
4-Methoxy-p-toluquinone is a quinone antibiotic found in the fungus Coprinus siniilis, Lentinus degener. 4-Methoxy-p-toluquinone has anti-bacterial, mycobacterial and fungal effects, but is weak against Gram-negative bacteria. The serum will inactivate it .

HY-N14519

Pacidamycin 7	Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial
Pacidamycin 7 has inhibitory effect on Pseudomonas aeruginosa. Pacidamycin 7 also has effect on a few strains of bacteria such as suppurative staphylococcus and Escherichia coli. Serum can reduce its antibacterial activity, pH also affects its antibacterial activity .

HY-N8375

Sieboldin	Source classification Balanophora involucrata Hook. f. Plants Balanophoraceae Saccharides Monosaccharides	Others
Sieboldin is a dihydrochalcone, which inhibits the production of advanced glycation end products (AGE) produced by bovine serum albumins (BSA), has free radical scavenging activity and cytotoxicity in cancer cell lines, and is also used to capture of methylglyoxal (MGO) from Malus baccata .

HY-130705A

Tachysterol 3	Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	VD/VDR Endogenous Metabolite
Tachysterol 3 is a photoproduct of Previtamin D₃ (HY-130705) .

HY-143712R

Allolithocholic acid (Standard)	Source classification Endogenous metabolite Steroids	Reference Standards Endogenous Metabolite
Dexamethasone metasulfobenzoate (sodium) (Standard) is the analytical standard of Dexamethasone metasulfobenzoate (sodium). This product is intended for research and analytical applications. Dexamethasone metasulfobenzoate sodium is a SARS-CoV-2 exonuclease (ExoN) inhibitor that binds to the catalytic site of ExoN .

HY-32351A

Calcifediol monohydrate 5+ Cited Publications 25-hydroxy Vitamin D3 monohydrate	Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	VD/VDR Endogenous Metabolite
Calcifediol monohydrate (25-hydroxy Vitamin D3 monohydrate), is an effective VDR ligand and VD supplement. Calcifediol is a prohormone of the vitamin D endocrine system (VDES) and is hydroxylated in the liver to produce the active form, calcitriol. Calcifediol can rapidly increase serum VD levels .

HY-32351

Calcifediol 5+ Cited Publications 25-Hydroxy Vitamin D3	Structural Classification Natural Products Other disease Classification of Application Fields Source classification Disease markers Metabolic Disease Endogenous metabolite Disease Research Fields	VD/VDR Endogenous Metabolite
Calcifediol (25-hydroxy Vitamin D3) is an effective VDR ligand and VD supplement. Calcifediol is a prohormone of the vitamin D endocrine system (VDES) and is hydroxylated in the liver to produce the active form, calcitriol. Calcifediol can rapidly increase serum VD levels .

HY-N12016

Fulvotomentoside B	Triterpenes Caprifoliaceae Terpenoids Source classification Plants Lonicera macrantha (D. Don) Spreng. Saccharides Monosaccharides	Others
Fulvotomentoside B is a saponin isolated from Lactobacillus flavus. Fulvotomentoside compounds can significantly reduce serum glutamate pyruvate transaminase (SGPT) and triacylglycerol (GT) levels in mice poisoned by CCl₄, d-galactosamine (d-gal) and acetaminophen, and significantly alleviate liver pathology. damage .

HY-W595136

(rac)-α-Carotene	Natural Products Leguminosae Ulex europaeus L. Source classification Plants	Endogenous Metabolite
(rac)-α-Carotene is the racemate of α-Carotene. α-Carotene is a carotenoid and potent antioxidant. Serum α-Carotene concentrations are inversely associated with the risk of all-cause mortality, cardiovascular disease, cancer, and mortality from all causes other than cardiovascular disease and cancer .

HY-113354

Anserine 4 Publications Verification	Immune System Disorder Microorganisms Ketones, Aldehydes, Acids Source classification Disease markers Nervous System Disorder Endogenous metabolite	Endogenous Metabolite
Anserine, a methylated form of Carnosine, is an orally active, natural Histidine-containing dipeptide found in skeletal muscle of vertebrates. Anserine is not cleaved by serum carnosinase and act as biochemical buffers, chelators, antioxidants, and anti-glycation agents. Anserine improves memory functions in Alzheimer's disease (AD)-model mice .

HY-W017445

Homogentisic acid lactone	Monophenols Microorganisms Source classification Phenols	Fungal
Homogentisic acid lactone (Compound 1) is a fungal metabolite with fungicidal activity, which is found in the fungus WF5. Homogentisic acid lactone is active against the plant pathogenic fungus F. graminearum. Homogentisic acid lactone can be used as a substrate in the determination of serum paraoxonase/arylesterase 1 (PON1) activity .

HY-N2638

Ilexsaponin A	Cardiovascular Disease Aquifoliaceae Triterpenes Classification of Application Fields Terpenoids Source classification Plants Disease Research Fields Tabernaemontana elegans Stapf	Apoptosis
Ilexsaponin A, isolated from the root of Ilex pubescens, attenuates ischemia-reperfusion-induced myocardial injury through anti-apoptotic pathway. Ilexsaponin A can reduce myocardial infarct size, lower the serum levels of LDH, AST and CK-MB, increase cellular viability and inhibit apoptosis in hypoxia/reoxygenation cardiomyocytes .

HY-N12329

Fumonisin B4	Microorganisms Ketones, Aldehydes, Acids Source classification	Others
Fumonisin B4 is a derivative of fumonisin. Fumonisin B4 has low albumin binding capacity .

HY-B1189

Meglutol Dicrotalic acid; 3-Hydroxy-3-methylglutaric acid	Cardiovascular Disease Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields	HMG-CoA Reductase (HMGCR) Autophagy Endogenous Metabolite
Meglutol is a lipid-lowering agent. Meglutol can reduces cholesterol, triglycerides, serum β-lipoprotein, and phospholipids, and inhibits the activity of HMG-CoA reductase (a rate-limiting enzyme in cholesterol biosynthesis). Meglutol can induce significant lipid oxidative damage in brain tissue. It is promising for research in the field of cardiovascular diseases and metabolic diseases .

HY-B0998

Dehydrocholic acid sodium Dehydrocholate sodium	Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields Steroids	Amylases Lipase Autophagy
Dehydrocholic acid (Dehydrocholate) sodium is an orally active hydrocholeretic agent. Dehydrocholic acid sodium modulates Autophagy, reduces serum amylase and lipase levels. Dehydrocholic acid sodium has the effects of promoting choleretic function, protecting the liver, reducing pancreatic damage, and regulating cholesterol metabolism. Dehydrocholic acid sodium can be used in the study of acute biliary pancreatitis and obstructive jaundice .

HY-B1393

Dehydrocholic acid Dehydrocholate	Source classification	Autophagy Amylases Lipase
Dehydrocholic acid (Dehydrocholate) is an orally active hydrocholeretic agent. Dehydrocholic acid modulates Autophagy, reduces serum amylase and lipase levels. Dehydrocholic acid has the effects of promoting choleretic function, protecting the liver, reducing pancreatic damage, and regulating cholesterol metabolism. Dehydrocholic acid can be used in the study of acute biliary pancreatitis and obstructive jaundice .

HY-W587784

Norbixin	Bixaceae Bixa orellana Linn. Ketones, Aldehydes, Acids Source classification Plants	PPAR
Norbixin is a carotenoid that has been found in B. orellana.It binds to PPARγ in a cell-free assay (Ki = 1.15 μM) . Norbixin attenuates hyperglycemia, hyperinsulinemia, and insulin resistance, as well as decreases serum lipid levels and cardiac levels of thiobarbituric acid reactive substances (TBARS) and glutathione (GSH) in a rat model of cardio-metabolic syndrome .

HY-32351AR

Calcifediol monohydrate (Standard) 25-hydroxy Vitamin D3 monohydrate (Standard)	Natural Products Source classification Endogenous metabolite	Reference Standards VD/VDR Endogenous Metabolite
Calcifediol monohydrate (Standard) is the analytical standard of Calcifediol (monohydrate). This product is intended for research and analytical applications. Calcifediol monohydrate (25-hydroxy Vitamin D3 monohydrate), is an effective VDR ligand and VD supplement. Calcifediol is a prohormone of the vitamin D endocrine system (VDES) and is hydroxylated in the liver to produce the active form, calcitriol. Calcifediol can rapidly increase serum VD levels .

HY-32351R

Calcifediol (Standard) 25-hydroxy Vitamin D3 (Standard)	Natural Products Microorganisms Other disease Source classification Disease markers Endogenous metabolite	Reference Standards VD/VDR Endogenous Metabolite
Calcifediol (Standard) is the analytical standard of Calcifediol. This product is intended for research and analytical applications. Calcifediol (25-hydroxy Vitamin D3) is an effective VDR ligand and VD supplement. Calcifediol is a prohormone of the vitamin D endocrine system (VDES) and is hydroxylated in the liver to produce the active form, calcitriol. Calcifediol can rapidly increase serum VD levels .

HY-N8487

7-Methoxyflavone	Flavonoids Neurological Disease Classification of Application Fields Flavones Leguminosae Zornia brasiliensis Source classification Plants Inflammation/Immunology Disease Research Fields	Cytochrome P450
7-Methoxyflavone is a flavonoid compound that can be isolated from Zornia brasiliensis. 7-Methoxyflavone can bind to human serum albumin and is an aromatase inhibitor. 7-Methoxyflavone has peripheral analgesic and certain antitumor activities. 7-Methoxyflavone is effective against chemical pain but has no significant effect on thermal pain .

HY-N7912

Pterosin A (2S)-Pterosin A	Pteridium aquilinum (L.) Kuhn Natural Products Source classification Plants Pteridiaceae	AMPK PEPCK GSK-3 GLUT Akt p38 MAPK Reactive Oxygen Species (ROS)
Pterosin A ((2S)-Pterosin A) is a sesquiterpene compound. Pterosin A is an orally active AMPK activator with anti-diabetic effect. Pterosin A can promote glucose uptake, increase serum insulin, and improve hyperglycemia and glucose intolerance. Pterosin A can prevent insulin-secreting cells death and reduce ROS production. Pterosin A can be used for the research of metabolic disease, such as diabetes .

HY-N2252

Licarin A (+)-Licarin A	Monophenols Saururaceae Neurological Disease Classification of Application Fields Simple Phenylpropanols Saururus chinensis (Lour.) Baill. Source classification Phenols Phenylpropanoids Plants Inflammation/Immunology Disease Research Fields	TNF Receptor Prostaglandin Receptor COX
Licarin A ((+)-Licarin A), a neolignan, significantly and dose-dependently reduces TNF-α production (IC₅₀=12.6 μM) in dinitrophenyl-human serum albumin (DNP-HSA)-stimulated RBL-2H3 cells. Anti-allergic effects. Licarin A reduces TNF-α and PGD2 production, and COX-2 expression .

HY-N13614

Centaurein	Flavonoids Flavones Source classification Amburana cearensis (Allemão) A.C.Sm. Plants Compositae	Bacterial IFNAR Nuclear Factor of activated T Cells (NFAT) NF-κB
Centaurein, a flavonoid, is an IFN-γ promoter enhancer. Centaurein up-regulates the activity of NFAT and NF-κB enhancers. Centaurein increases the IFN-γ expression in T and NK cells and the serum IFN-γ level in mice. Centaureidin completely relaxes the contractions in intact rat aortic rings. Centaurein effectively protects mice against Listeria infection ^[1][2][3][4].

HY-N2638R

Ilexsaponin A (Standard)	Aquifoliaceae Triterpenes Terpenoids Source classification Plants Tabernaemontana elegans Stapf	Reference Standards Apoptosis
Ilexsaponin A (Standard) is the analytical standard of Ilexsaponin A. This product is intended for research and analytical applications. Ilexsaponin A, isolated from the root of Ilex pubescens, attenuates ischemia-reperfusion-induced myocardial injury through anti-apoptotic pathway. Ilexsaponin A can reduce myocardial infarct size, lower the serum levels of LDH, AST and CK-MB, increase cellular viability and inhibit apoptosis in hypoxia/reoxygenation cardiomyocytes .

HY-113354R

Anserine (Standard)	Immune System Disorder Microorganisms Ketones, Aldehydes, Acids Source classification Disease markers Nervous System Disorder Endogenous metabolite	Reference Standards Endogenous Metabolite
Anserine (Standard) is the analytical standard of Anserine. This product is intended for research and analytical applications. Anserine, a methylated form of Carnosine, is an orally active, natural Histidine-containing dipeptide found in skeletal muscle of vertebrates. Anserine is not cleaved by serum carnosinase and act as biochemical buffers, chelators, antioxidants, and anti-glycation agents. Anserine improves memory functions in Alzheimer's disease (AD)-model mice[1][2].

HY-B1189R

Meglutol (Standard)	Ketones, Aldehydes, Acids Source classification Endogenous metabolite	HMG-CoA Reductase (HMGCR) Autophagy Endogenous Metabolite
Meglutol (Standard) is the analytical standard of Meglutol. This product is intended for research and analytical applications. Meglutol is a lipid-lowering agent. Meglutol can reduces cholesterol, triglycerides, serum β-lipoprotein, and phospholipids, and inhibits the activity of HMG-CoA reductase (a rate-limiting enzyme in cholesterol biosynthesis). Meglutol can induce significant lipid oxidative damage in brain tissue. It is promising for research in the field of cardiovascular diseases and metabolic diseases .

HY-141508

Flazin	Simaroubaceae Source classification Plants Indole Alkaloids Brucea javanica (L.) Merr.	Xanthine Oxidase NO Synthase
Flazin is a non-enzymatic protein glycation inhibitor, also inhibits peroxynitrite (ONOO ^-), with an IC₅₀ value of 85.31 μM for bovine serum albumin (BSA) glycation and an EC₅₀ value of 71.99 μM for ONOO ^-. Flazin can be used for researching diabetes and neuronal disorders. Flazin also can used as a lipid droplet (LD) regulator against lipid disorders, and a xanthine oxidase (XOD) inhibitor .

HY-N0407

Picroside I 6'-Cinnamoylcatalpol	Iridoids Classification of Application Fields Terpenoids Source classification Scrophulariaceae Plants Picrorhiza scrophulariiflora Pennell Inflammation/Immunology Disease Research Fields	STAT
Picroside I is the major ingredient of Picrorhiza scrophulariiflora. Picrorhiza scrophulariiflora is a high value medicinal herb due to rich source of hepatoprotective metabolites, Picroside-I and Picroside-II . Picroside I is a promising agent for the management of asthma. Picroside I reduces the inflammation significantly at its higher dose. Picroside I also downregulates pSTAT6 and GATA3 expressions. Picroside I dose-dependently increases the serum levels of IFN-γ .

HY-W014130

N-Acetyl-L-arginine 1 Publications Verification Ac-Arg-OH	Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease markers Other Diseases Endocrine diseases Nervous System Disorder Endogenous metabolite Disease Research Fields	Endogenous Metabolite
N-Acetyl-L-arginine (Ac-Arg-OH) is one of the guanidino compounds found elevated in the serum of a hemodialyzed renal insufficient (uremic) pediatric population. N-Acetyl-L-arginine shows synergistic activity with glycine buffer. N-Acetyl-L-arginine suppresses the aggregation of intravenous immunoglobulins with a minimum decrease in transition temperature. N-Acetyl-L-arginine dramatically reduces IL-1 expression in the presence of silicone oil. N-Acetyl-L-arginine also demonstrates colloidal stability .

Cat. No.	Product Name	Chemical Structure

HY-W012946S

2-Furoic acid-d3
2-Furoic acid-d₃ is the deuterium labeled 2-Furoic acid . 2-Furoic acid (Furan-2-carboxylic acid) is an organic compound produced through furfural oxidation . 2-Furoic acid exhibits hypolipidemic effet, lowers both serum cholesterol and serum triglyceride levels in rats .

HY-W654091

(R)-Butyryl carnitine-d5 chloride
(R)-Butyryl carnitine-d₅ chloride is deuterium labeled Butyryl-L-carnitine (chloride). Butyryl-L-carnitine chloride is an acylcarnitine that can be isolated from Plasma/Serum .

HY-113486S

(S)-Lathosterol-d4
(S)-Lathosterol-d₄ is the deuterium labeled (S)-Lathosterol. Lathosterol is a cholesterol-like molecule. Serum Lathosterol concentration is an indicator of whole-body cholesterol synthesis .

HY-N2341S

Palmitelaidic acid-d13
Palmitelaidic acid-d₁₃ is the deuterium labeled Palmitelaidic Acid. Palmitelaidic Acid (9-trans-Hexadecenoic acid) is the trans isomer of palmitoleic acid. Palmitoleic acid is one of the most abundant fatty acids in serum and tissue.

HY-B1189S

Meglutol-d3
Meglutol-d₃ is the deuterium labeled Meglutol . Meglutol is an antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids, and inhibits the activity of hydroxymethylglutarryl CoA reductases, which is the rate limiting enzyme in the biosynthesis of cholesterol.

HY-32351S

Calcifediol-d3
Calcifediol-d₃ is a deuterium labeled Calcifediol. Calcifediol, is an effective VDR ligand and VD supplement. Calcifediol is a prohormone of the vitamin D endocrine system (VDES) and is hydroxylated in the liver to produce the active form, calcitriol. Calcifediol can rapidly increase serum VD levels .

HY-113283S

Homogentisic acid-13C6
Homogentisic acid- ¹³C₆ is the ¹³C-labeled Homogentisic acid (HY-113283). Homogentisic acid is a specific metabolite that accumulates in the urine and serum. Homogentisic acid can be used for diagnosis of alkaptonuria. Homogentisic acid is a phenolic acid .

HY-118827S

Vedaprofen-d3
Vedaprofen-d₃ is the deuterium labeled Vedaprofen. Vedaprofen (Quadrisol) is a COX-1 selective nonsteroidal anti-inflammatory agent (NSAID) for serum TxB2 and exudate PGE2 inhibition . Vedaprofen is a Escherichia coli (E. coli) sliding clamp (SC) inhibitor with the IC₅₀ of 222 μM .

HY-W011297S3

Methyl arachidonate-13C5
Methyl arachidonate- ¹³C₅ (Arachidonic acid methyl ester- ¹³C₅) is ¹³C labeled Methyl arachidonate. Methyl arachidonate (Arachidonic acid methyl ester) is a fatty acid methyl ester resulting from the formal condensation of the carboxy group of arachidonic acid with methanol. Methyl arachidonate has activity of human blood serum metabolite .

HY-W011297S2

Methyl arachidonate-13C4
Methyl arachidonate- ¹³C₄ (Arachidonic acid methyl ester- ¹³C₄) is ¹³C labeled Methyl arachidonate. Methyl arachidonate (Arachidonic acid methyl ester) is a fatty acid methyl ester resulting from the formal condensation of the carboxy group of arachidonic acid with methanol. Methyl arachidonate has activity of human blood serum metabolite .

HY-D0932S

Sudan IV-d6

Sudan IV-d₆ (Solvent Red 24-d₆) is the deuterium labeled Sudan IV(HY-D0932). Sudan IV is an agonist of the aryl hydrocarbon receptor (AhR) that activates downstream signaling pathways and induces CYP1A1 expression. Sudan IV promotes CYP1A1 gene transcription by activating AhR-ARNT heterodimers and binding to exogenous response elements (XREs) on DNA, thereby enhancing drug metabolizing enzyme activity. Sudan IV can be used to study the toxicity mechanisms of industrial dyes and the effects of interactions with serum proteins (such as bovine serum albumin (BSA)) on their distribution in vivo. Sudan IV is a fat-soluble diazo dye that can be used to stain lipids, triglycerides, and lipoproteins on frozen sections .

HY-32351AS

Calcifediol-d6 monohydrate
Calcifediol-d₆ monohydrate is the deuterium labeled Calcifediol monohydrate. Calcifediol monohydrate (25-hydroxy Vitamin D3 monohydrate), is an effective VDR ligand and VD supplement. Calcifediol is a prohormone of the vitamin D endocrine system (VDES) and is hydroxylated in the liver to produce the active form, calcitriol. Calcifediol can rapidly increase serum VD levels .

HY-32351AS1

Calcifediol-13C5 monohydrate
Calcifediol- ¹³C₅ monohydrate is the ¹³C-labeled Calcifediol monohydrate. Calcifediol monohydrate (25-hydroxy Vitamin D3 monohydrate), is an effective VDR ligand and VD supplement. Calcifediol is a prohormone of the vitamin D endocrine system (VDES) and is hydroxylated in the liver to produce the active form, calcitriol. Calcifediol can rapidly increase serum VD levels .

HY-113354S

Anserine-d4
Anserine-d₄ is the deuterium labeled Anserine. Anserine, a methylated form of Carnosine, is an orally active, natural Histidine-containing dipeptide found in skeletal muscle of vertebrates. Anserine is not cleaved by serum carnosinase and act as biochemical buffers, chelators, antioxidants, and anti-glycation agents. Anserine improves memory functions in Alzheimer's disease (AD)-model mice .

HY-143712S1

Allolithocholic Acid-d4
Allolithocholic Acid-d₄ (3α-hydoxy-5α-Cholaoic Acid-d₄, allo-LCA-d₄) is deuterium labeled Allolithocholic acid. Allolithocholic acid is a steroid acid could found in normal serum and feces. Allolithocholic acid facilitates excretion, absorption, and transport of fats and sterols in the intestine and liver .

HY-113354S1

Anserine-d4 hydrochloride

Anserine-d₄ hydrochloride is the deuterium labeled Anserine (HY-113354). Anserine, a methylated form of Carnosine, is an orally active, natural Histidine-containing dipeptide found in skeletal muscle of vertebrates. Anserine is not cleaved by serum carnosinase and act as biochemical buffers, chelators, antioxidants, and anti-glycation agents. Anserine improves memory functions in Alzheimer's disease (AD)-model mice .

HY-B1858S

Isoprothiolane-d4

Isoprothiolane-d₄ is the deuterium labeled Isoprothiolane (HY-B1858). Isoprothiolane is a blast fungicide with antifungal, anti-inflammatory and insecticidal activities. Isoprothiolane primarily acts on fungi during the penetration and growth stages of infecting hyphae. Isoprothiolane can be used as an insecticide, pesticide, etc. In addition, Isoprothiolane can reduce serum phospholipid and total lipid concentrations, regulating lipid metabolism. Isoprothiolane is also used in the research of fatty liver .

HY-13402S

Varespladib-d7

Varespladib-d₇ (LY315920-d₇) is a deuterated labeled Varespladib (HY-13402). Varespladib is a potent and selective group IIA, secretory phospholipase A2 (sPLA2) inhibitor with an IC₅₀ of 9 nM. Varespladib exhibits the significant inhibitory effect on sPLA2 activity in serum from various species including rat, rabbit, guinea pig and human with IC₅₀s of 8.1 nM, 5.0 nM, 3.2 nM and 6.2 nM, respectively .

HY-W268542S1

4-Acetylaminoantipyrine-d3

4-Acetylaminoantipyrine-d₃ is the deuterium labeled 4-Acetylaminoantipyrine (HY-W268542). 4-Acetylaminoantipyrine (4-AA) is a derivative of antipyrine (HY-B0171). 4-Acetylaminoantipyrine acts as a PGE2-dependent blocker and inhibitor of cyclooxygenase (COX) . 4-Acetylaminoantipyrine can inhibit Cu/ZnSOD . 4-Acetylaminoantipyrine can spontaneously bind with bovine serum albumin (BSA) and alter its conformation .

HY-146925S

15:0 Lyso PC-d5

15:0 Lyso PC-d₅ is deuterium labeled 15:0 Lyso PC (HY-W329357). 15:0 Lyso PC is a lysophosphatidylcholine (Lyso PC), a product of phospholipase A2 (PLA2) hydrolysis of phosphatidylcholine (PC) and is involved in cell membrane remodeling and inflammatory signaling. 15:0 Lyso PC demonstrates significant lipid metabolism disturbances in the serum of patients with ischemic heart disease (IHD) and ischemic cardiomyopathy (ICM). 15:0 Lyso PC can be used as a lipid biomarker for cardiovascular disease.

HY-113509S

Lipoxin A4-d5

Lipoxin A4-d₅ is the deuterium labeled Lipoxin A4. Lipoxin A4 (LXA4), an endogenous lipoxygenase-derived eicosanoid mediator, has potent dual pro-resolving and anti-inflammatory properties . Lipoxin A4 inhibits proliferation and inflammatory cytokine/chemokine production of human epidermal keratinocytes (NHEKs) associated with the ERK1/2 and NF-kB pathways . Lipoxin A4 inhibits serum amyloid A (SAA)-mediated IL-8 release with an IC₅₀ value of 25.74 nM .

HY-15790S

Elobixibat-d5

Elobixibat-d₅ is the deuterium labeled Elobixibat (HY-15790). Elobixibat (A 3309; AZD 7806) is orally active, bile acid transporter (IBAT) inhibitor with IC₅₀ values ??of 0.53 nM (human IBAT), 0.13 nM (mouse IBAT), and 5.8 nM (canine IBAT). Elobixibat can lower LDL cholesterol, increase serum GLP-1, promote colonic motility, and has the potential to treat metabolic syndrome. Elobixibat can be used in the study of chronic functional constipation (CIC), dyslipidemia, non-alcoholic hepatitis, and liver tumors in the elderly .

HY-W700491

AalphaC-15N3

AalphaC- ¹⁵N₃ (2-Amino-α-carboline- ¹⁵N₃) is ¹⁵N labeled AalphaC. AalphaC (AαC) is a potential carcinogen with carcinogenic activity. AalphaC is an important biomarker in tobacco smoke and is associated with tobacco smoke exposure. Urinary concentrations of AalphaC are significantly higher in dedicated smokers than in non-smokers, indicating its importance in monitoring tobacco exposure. AalphaC levels increase significantly with increasing serum nicotine levels, indicating its close relationship with tobacco use. In addition, consuming high-temperature cooked beef significantly increases the amount of AalphaC in urine, while consuming vegetables is associated with a decrease in AalphaC concentrations. Smoking half a pack of cigarettes is associated with a significant increase in the amount of AalphaC, which further confirms the biological activity of AalphaC and its association with dietary habits .

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