2. Vitamin D Related/Nuclear Receptor Metabolic Enzyme/Protease
  3. VD/VDR Endogenous Metabolite
  4. Tachysterol 3

Tachysterol 3 is a photoproduct of Previtamin D3 (HY-130705).

For research use only. We do not sell to patients.

Tachysterol 3

Tachysterol 3 Chemical Structure

CAS No. : 17592-07-3

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Based on 1 publication(s) in Google Scholar

Other Forms of Tachysterol 3:

Tachysterol 3 Related Antibodies

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  • Purity & Documentation

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Description

Tachysterol 3 is a photoproduct of Previtamin D3 (HY-130705)[1][2].

IC50 & Target

Human Endogenous Metabolite

 

In Vitro

Tachysterol 3 can be hydroxylated by CYP11A1 and CYP27A1[2].
Tachysterol 3 is detected in human serum at a concentration of 7.3 ± 2.5 ng/mL[2].
Tachysterol 3 hydroxyderivatives show high-affinity binding to the ligan-binding domain (LBD) of the liver X receptor (LXR) α and β, and the peroxisome proliferator-activated receptor γ (PPARγ) in LanthaScreen TR-FRET coactivator assays[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Tachysterol 3 Related Antibodies
Molecular Weight

384.64

Formula

C27H44O
CAS No.
Appearance

Oil

Color

Colorless to light yellow

SMILES

O[C@@H]1CC(/C=C/C2=CCC[C@]3(C)[C@@H]([C@H](C)CCCC(C)C)CC[C@@]23[H])=C(C)CC1
Structure Classification
Initial Source
Shipping

Shipping with dry ice.
Storage

-80°C, protect from light, stored under nitrogen

*The compound is unstable in solutions, freshly prepared is recommended.

Solvent & Solubility
In Vitro: 

DMSO : 20 mg/mL (52.00 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5998 mL 12.9992 mL 25.9983 mL
5 mM 0.5200 mL 2.5998 mL 5.1997 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.68%

SDS (480 KB)

COA (246 KB) HNMR (466 KB) RP-HPLC (294 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.5998 mL 12.9992 mL 25.9983 mL 64.9958 mL
5 mM 0.5200 mL 2.5998 mL 5.1997 mL 12.9992 mL
10 mM 0.2600 mL 1.2999 mL 2.5998 mL 6.4996 mL
15 mM 0.1733 mL 0.8666 mL 1.7332 mL 4.3331 mL
20 mM 0.1300 mL 0.6500 mL 1.2999 mL 3.2498 mL
25 mM 0.1040 mL 0.5200 mL 1.0399 mL 2.5998 mL
30 mM 0.0867 mL 0.4333 mL 0.8666 mL 2.1665 mL
40 mM 0.0650 mL 0.3250 mL 0.6500 mL 1.6249 mL
50 mM 0.0520 mL 0.2600 mL 0.5200 mL 1.2999 mL
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Tachysterol 3 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tachysterol 317592-07-3Tachysterol3Tachysterol-3VD/VDREndogenous MetaboliteVitamin DVitamin D receptorvitamin Dprevitamin D3CYP11A1CYP27A1human serumInhibitorinhibitorinhibit

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