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  4. Estradiol 3-methyl ether

Estradiol 3-methyl ether  (Synonyms: 3-O-Methyl estradiol; 17β-Estradiol 3-methyl ether; 3-Methoxyestradiol)

Cat. No.: HY-W008581
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Estradiol 3-methyl ether is a synthetic estrogen. Estradiol 3-methyl ether can disrupt microtubule networks in V79 cells with an EC50 of 9 μM, as well as inhibiting cell proliferation. Estradiol 3-methyl ether decreases the serum cholesterol levels and increases body weight loss, which indicates feminizing activity in HFD murine model.

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Estradiol 3-methyl ether Chemical Structure

Estradiol 3-methyl ether Chemical Structure

CAS No. : 1035-77-4

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Estradiol 3-methyl ether Related Antibodies

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Description

Estradiol 3-methyl ether is a synthetic estrogen. Estradiol 3-methyl ether can disrupt microtubule networks in V79 cells with an EC50 of 9 μM, as well as inhibiting cell proliferation. Estradiol 3-methyl ether decreases the serum cholesterol levels and increases body weight loss, which indicates feminizing activity in HFD murine model[1][2].

Molecular Weight

286.41

Formula

C19H26O2
CAS No.
SMILES

C[C@]12CC[C@]3([H])C4=CC=C(OC)C=C4CC[C@@]3([H])[C@]1([H])CC[C@]2([H])O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (349.15 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.4915 mL 17.4575 mL 34.9150 mL
5 mM 0.6983 mL 3.4915 mL 6.9830 mL
View the Complete Stock Solution Preparation Table

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In Vivo Dissolution Calculator
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Purity & Documentation
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Complete Stock Solution Preparation Table

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.4915 mL 17.4575 mL 34.9150 mL 87.2875 mL
5 mM 0.6983 mL 3.4915 mL 6.9830 mL 17.4575 mL
10 mM 0.3491 mL 1.7457 mL 3.4915 mL 8.7287 mL
15 mM 0.2328 mL 1.1638 mL 2.3277 mL 5.8192 mL
20 mM 0.1746 mL 0.8729 mL 1.7457 mL 4.3644 mL
25 mM 0.1397 mL 0.6983 mL 1.3966 mL 3.4915 mL
30 mM 0.1164 mL 0.5819 mL 1.1638 mL 2.9096 mL
40 mM 0.0873 mL 0.4364 mL 0.8729 mL 2.1822 mL
50 mM 0.0698 mL 0.3491 mL 0.6983 mL 1.7457 mL
60 mM 0.0582 mL 0.2910 mL 0.5819 mL 1.4548 mL
80 mM 0.0436 mL 0.2182 mL 0.4364 mL 1.0911 mL
100 mM 0.0349 mL 0.1746 mL 0.3491 mL 0.8729 mL
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Estradiol 3-methyl ether Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Estradiol 3-methyl ether1035-77-43-O-Methyl estradiol 17β-Estradiol 3-methyl ether 3-MethoxyestradiolBiochemical Assay ReagentsInhibitorinhibitorinhibit

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