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Pathways Recommended:	Antibody-drug Conjugate/ADC Related

Results for "

human monoclonal antibody

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Antibody (16) Antibody-Drug Conjugates (ADCs) (13) Adenylate Cyclase (2) Akt (7) ALCAM/CD166 (1) Amyloid-β (4) Anaplastic lymphoma kinase (ALK) (2) Angiotensin-converting Enzyme (ACE) (2) ANGPTL (1) Antibiotic (1) Antifolate (1) Apoptosis (19) Bacterial (8) Biochemical Assay Reagents (1) c-Fms (5) c-Kit (3) c-Met/HGFR (6) c-Myc (1) C-type Lectin-like Receptors (CTLRs) (5) Cadherin (2) Calcium Channel (1) Caspase (2) CCR (7) CD1 (1) CD19 (4) CD2 (1) CD20 (5) CD22 (3) CD276/B7-H3 (2) CD28 (3) CD3 (9) CD38 (4) CD47 (6) CD6 (1) CD73 (6) CD74 (1) CGRP Receptor (2) Claudin (4) CMV (1) Complement System (13) CTLA-4 (11) CX3CR1 (2) CXCR (5) Dan family (1) DNA/RNA Synthesis (2) EGFR (21) ERK (1) Estrogen Receptor/ERR (1) Factor VIII (1) Factor Xa (4) Factor XI (1) Fc Receptor (FcR) (4) Ferroptosis (1) FGFR (5) Filovirus (4) FLT3 (1) Galectin (1) Gap Junction Protein (1) GCGR (1) GLP Receptor (1) Glycoprotein VI (2) Guanylate Cyclase (1) HBV (3) HCV (1) Histamine Receptor (1) HIV (7) HMG Family (2) HSP (1) HSV (1) IFNAR (13) IGF-1R (10) Influenza Virus (8) Insulin Receptor (5) Integrin (16) Interleukin Related (91) JNK (1) Kallikrein (1) Keap1-Nrf2 (2) LAG-3 (13) LOX-1 (1) LPL Receptor (3) Macrophage migration inhibitory factor (MIF) (1) MDM-2/p53 (2) MHC (4) Microtubule/Tubulin (7) MMP (2) mRNA (1) mTOR (1) Mucin (5) Myosin (1) nAChR (2) NAMPT (1) Neurokinin Receptor (1) Neurotensin Receptor (1) NF-κB (10) NO Synthase (1) NOD-like Receptor (NLR) (3) Notch (3) NTPDase (2) Orexin Receptor (OX Receptor) (7) P-glycoprotein (1) P-selectin (1) p38 MAPK (2) PAI-1 (2) PARP (1) PCSK9 (4) PD-1/PD-L1 (36) PDGFR (1) PERK (2) Phosphatase (1) PI3K (2) PSMA (3) RABV (1) Radionuclide-Drug Conjugates (RDCs) (2) RANKL/RANK (2) Ras (2) Reactive Oxygen Species (ROS) (2) RSV (11) SARS-CoV (31) Ser/Thr Kinase (1) Ser/Thr Protease (3) Sialyltransferase (1) SLC39 (Zinc Transporter) (1) Small Interfering RNA (siRNA) (1) Sodium Phosphate Cotransporter (1) STAT (3) Survivin (1) Syk (1) Tau Protein (7) TGF-beta/Smad (5) TGF-β Receptor (7) Thrombin (1) Thyroid Hormone Receptor (1) Tie (3) Tim3 (4) Tissue Factor Pathway Inhibitor (TFPI) (2) TNF Receptor (57) Toll-like Receptor (TLR) (5) Topoisomerase (2) Transferrin Receptor (2) Transmembrane Glycoprotein (46) Transthyretin (TTR) (3) TREM receptor (4) Trk Receptor (7) TROP2 (2) TSH Receptor (2) Tyrosinase (2) VAP-1 (2) VEGFR (11) VISTA (3) Wnt (4) α-synuclein (1)
By Research Areas:	Cancer (360) Cardiovascular Disease (26) Endocrinology (10) Infection (70) Inflammation/Immunology (270) Metabolic Disease (22) Neurological Disease (36)
Oligonucleotides:	mRNA (1)

649

Inhibitors & Agonists

Fluorescent Dye

Peptides

MCE Kits

682

Inhibitory Antibodies

Recombinant Proteins

Antibodies

Oligonucleotides

Erenumab AMG-334	CGRP Receptor	Others
Erenumab is a fully human monoclonal antibody. Erenumab inhibits the calcitonin gene–related peptide (CGRP) receptor. Erenumab can be used for the prevention of episodic migraine .

Zalifrelimab AGEN1884	CTLA-4	Cancer
Zalifrelimab (AGEN1884) is a fully human IgG1 monoclonal antibody targeting CTLA-4 (CTLA-4). Zalifrelimab antagonizes the inhibitory checkpoints of immune cell activation regulated by CTLA-4 signaling .

Bermekimab MABp1	Interleukin Related	Inflammation/Immunology Cancer
Bermekimab (MABp1) is a human monoclonal antibody targeting interleukin-1α(IL-1α) . Bermekimab can prevent tumor-related inflammation. Bermekimab can be used in the research of atopic dermatitis .

Bertilimumab CAT 213; iCo-008	CCR	Inflammation/Immunology
Bertilimumab (CAT 213; iCo-008) is a human monoclonal antibody targeting eotaxin-1 (CCL11). Bertilimumab has the potential for allergic disorders research .

Garadacimab 1 Publications Verification CSL312	Factor Xa	Cardiovascular Disease
Garadacimab (CSL312) is a first-in-class, fully human IgG4 monoclonal antibody targeting activated factor XII (FXIIa). Garadacimab has the potential for hereditary angioedema research .

Sarilumab Anti-human IL6Rα, human antibody	Interleukin Related	Inflammation/Immunology Cancer
Sarilumab (Anti-Human IL6Rα, Human Antibody) is a human immunoglobulin G1 monoclonal antibody. Sarilumab, a interleukin-6 (IL-6) receptor antagonist, binds to the IL-6 receptor with high affinity and inhibits cis and trans signaling by IL-6, resulting in reduced inflammation. Sarilumab can be used for the research of Rheumatoid arthritis .

Garetosmab 1 Publications Verification REGN 2477	TGF-β Receptor	Inflammation/Immunology
Garetosmab (REGN 2477) is a fully human IgG4 monoclonal antibody that specifically inhibits activin A. Garetosmab can be used for fibrodysplasia ossificans progressiva (FOP) research .

Onvatilimab JNJ-61610588; CI-8993; VSTB112	VISTA	Cancer
Onvatilimab (JNJ-61610588) is a human IgG1κ anti-VISTA (V-domain Ig Suppressor of T-cell Activation) monoclonal antibody. Onvatilimab can be used in colorectal cancer research .

Aducanumab BIIB037	Amyloid-β	Neurological Disease
Aducanumab (BIIB037) is a human monoclonal antibody that selectively targets aggregated amyloid-beta (Aβ). Aducanumab shows brain penetration, and can be used for Alzheimer's disease (AD) research .

Oleclumab 1 Publications Verification MEDI9447	CD73	Cancer
Oleclumab (MEDI9447) is a human IgG1λ monoclonal antibody targeting CD73 and inhibits the exonuclease activity of the extracellular enzyme CD73. Oleclumab can adjust the composition of bone marrow and lymphoid infiltrating leukocyte populations in the tumor microenvironment and has anti-tumor activity .

Afasevikumab RG 7624; RO 5553110; NI-1401	Interleukin Related	Inflammation/Immunology
Afasevikumab (RG 7624; RO 5553110; NI-1401) is a fully human monoclonal IgG1κ antibody neutralizing both IL-17A and IL-17F. Afasevikumab has anti-inflammatory activities .

Canakinumab Ilaris; ACZ 885	Interleukin Related	Inflammation/Immunology Cancer
Canakinumab (ACZ885) is a recombinant human *anti-IL-1β* monoclonal antibody. Canakinumab shows IC₅₀ values of 43.6 and 40.8 pM for human and marmoset IL-1β, respectively. The mode of action of canakinumab is based on the neutralization of IL-1β signaling, resulting in suppression of inflammation related to disorders of autoimmune origin .

Vantictumab 1 Publications Verification OMP-18R5	Wnt	Cancer
Vantictumab (OMP-18R5) is a fully human IgG2 monoclonal antibody. Vantictumab inhibits Wnt pathway signaling by binding to FZD1/2/5/7/8 receptors. Vantictumab can be studied against cancers through direct actions on tumor cells, including CSCs, and effects on the stroma, such as metastatic HER2-negative breast cancer and metastatic pancreatic adenocarcinoma .

Panitumumab 1 Publications Verification ABX-EGF	EGFR	Cancer
Panitumumab (ABX-EGF) is a fully human IgG2 anti-EGFR monoclonal antibody with anti-tumor activity. Panitumumab inhibits tumor cell proliferation, survival and angiogenesis. Panitumumab can be used in the research of cancers, such as colon cancer .

Panitumumab (powder) ABX-EGF (powder)	EGFR	Cancer
Panitumumab (ABX-EGF) (powder) is a fully human IgG2 anti-EGFR monoclonal antibody with anti-tumor activity. Panitumumab (powder) inhibits tumor cell proliferation, survival and angiogenesis. Panitumumab (powder) can be used in the research of cancers, such as colon cancer .

Abrilumab	Integrin	Infection Inflammation/Immunology Cancer
Abrilumab is a fully **human monoclonal antibody directed against α4β7**. Abrilumab selectively binds the α4β7 integrin heterodimer. Abrilumab can be used for the research of inflammatory bowel disease (IBD) .

Panitumumab (anti-EGFR)	EGFR	Cancer
Panitumumab (anti-EGFR) is a fully human IgG2 anti-EGFR monoclonal antibody with anti-tumor activity. Panitumumab (anti-EGFR) inhibits tumor cell proliferation, survival and angiogenesis. Panitumumab (anti-EGFR) can be used in the research of cancers, such as colon cancer .

Raxibacumab ABthrax	Bacterial	Infection
Raxibacumab (ABthrax) is a human IgG1 monoclonal antibody against Bacillus anthracis protective antigen (PA). Raxibacumab blocks the toxin’s deleterious effects by preventing binding of the protective antigen component of the anthrax toxin to its receptors in host cells, thereby blocking the toxin’s deleterious effects. Raxibacumab can be used for anti-anthrax research .

VX5 VX5/5261	CXCR	Inflammation/Immunology Cancer
VX5 is a humanized IgG1κ monoclonal antibody inhibitor targeting BCA-1/CXCL13. VX5 significantly inhibits human CXCL13-mediated internalization of CXCR5, blocks both human and mouse CXCL13-dependent B-cells chemotaxis and migration (EC₅₀s for 105 and 253 nM for human tonsillar and pre-B-697-hCXCR5 cells, respectively). VX5 can be used to study autoimmune diseases like multiple sclerosis and arthritis, and cancers like gastric lymphomas and colon cancer .

TRX585	C-type Lectin-like Receptors (CTLRs)	Infection Inflammation/Immunology Cancer
TRX585 is a humanised anti-immunoglobulin-like transcript 5 (ILT5) monoclonal antibody. TRX585 has a potent immunoregulatory activity. TRX585 significantly activates human T cells and upregulates NKG2D and Fas ligand, followed by enhancing antitumor activity with potent cytotoxicity. TRX585 can be used for viral infections and malignancies research .

LY-2624587	CXCR Apoptosis p38 MAPK Akt	Cancer
LY-2624587 is a humanized IgG4 monoclonal antibody antagonist targeting CXCR4. LY-2624587 blocks SDF-1/CXCR4 interaction and SDF-1-induced GTP binding. LY-2624587 significantly inhibits cell migration and induces apoptosis in human lymphoma and leukemia cells. LY-2624587 also inhibits CXCR4 and SDF-1 mediated cell signaling including activation of MAPK and AKT. LY-2624587 can be used for human hematological malignancies like acute myeloid leukemia (AML) research .

Alsevalimab 1 Publications Verification	CD276/B7-H3	Cancer
Alsevalimab is a humanized, afucosylated IgG1 monoclonal antibody against B7-H4. Alsevalimab blocks the binding of the B7-H4 protein to the receptors on the surface of T cells, reversing the immunosuppressive state in the tumor microenvironment, thereby activating the killing effect of T cells on cancer cells. Alsevalimab can be used in combination with Pembrolizumab (HY-P9902), and shows good safety profiles .

Zelminemab AMG-301	Adenylate Cyclase	Neurological Disease
Zelminemab (AMG-301) is a humanized monoclonal antibody that inhibits PACAP type I (PAC1) receptor .

Anti-ALPP Antibody SGN-ALPV antibody	Phosphatase	Cancer
Anti-ALPP Antibody (SGN-ALPV antibody) is a human monoclonal antibody (mAb) targeting ALPP. Anti-ALPP Antibody can be used in solid tumors research .

Tomuzotuximab Anti-human EGFR Recombinant antibody; CetuxiMab-GEX, GEXMab52201	EGFR Apoptosis	Cancer
Tomuzotuximab (Anti-Human EGFR Recombinant Antibody) is a fully human glycoengineered IgG1 monoclonal antibody against EGFR. Tomuzotuximab has anticancer effects .

Vapaliximab 2D10	VAP-1	Inflammation/Immunology
Vapaliximab (2D10) is a monoclonal antibody against human VAP-1 .

Balertatug	TNF Receptor	Cancer
Balertatug is a human IgG1K antibody targeting CD70. The corresponding isotype control is: Human lgG1 kappa, lsotype Control (HY-P99001) .

Atidortoxumab	Bacterial	Infection
Atidortoxumab is a human IgG1κ monoclonal antibody that targets Staph aureus alpha toxin .

Adalimumab 10+ Cited Publications Anti-human TNF-alpha, human antibody	TNF Receptor Bacterial	Inflammation/Immunology Cancer
Adalimumab is a human monoclonal IgG1 antibody targeting tumour necrosis factor α (TNF-α).

Indusatumab 5F9 monoclonal antibody	Guanylate Cyclase	Cancer
Indusatumab (5F9 Monoclonal antibody) is a monoclonal antibody against human GUCY2C (Guanylate cyclase 2C). Indusatumab can be used to synthesize ADCs, such as Indusatumab vedotin (HY-P99662). Indusatumab can be used in cancer research .

Anti-Tenascin C Antibody Neuradiab antibody	Transmembrane Glycoprotein	Cancer
Anti-Tenascin C Antibody (Neuradiab antibody) is a human monoclonal antibody (mAb) targeting Tenascin C. Anti-Tenascin C Antibody can be used in Glioblastoma research. Recommended isotype control: Human IgG1 kappa, Isotype Control (HY-P99001) .

Alextatug	DNA/RNA Synthesis	Inflammation/Immunology
Alextatug is an anti-PABPC1 human IgG1 λ7 monoclonal antibody .

MG1113A	Tissue Factor Pathway Inhibitor (TFPI)	Others
MG1113A is a human monoclonal antibody (mAb) targeting TFPI. MG1113A can be used in Haemophilia research.

Balstilimab AGEN2034	PD-1/PD-L1	Inflammation/Immunology Cancer
Balstilimab (AGEN2034) is a fully human monoclonal IgG4 antibody against PD-1 .

REGN-5054	Transmembrane Glycoprotein	Cancer
REGN5054 is a fully human monoclonal IgG1 antibody that binds specifically to human and cynomolgus CD8 expressed on T cells .

Vadastuximab Anti-human CD33 Recombinant antibody	Transmembrane Glycoprotein	Cancer
Vadastuximab (Anti-Human CD33 Recombinant Antibody) is a humanized monoclonal antibody targeting CD33. Vadastuximab can be used to synthesize an ADC compound, Vadastuximab talirine .

Azintuxizumab	ADC Antibody	Cancer
Azintuxizumab is an anti-SLAMF7 human IgG4κ monoclonal antibody. Azintuxizumab can be used in the synthesis of antibody-drug conjugate (ADC), Azintuxizumab vedotin .

Ustekinumab 3 Publications Verification CNTO-1275; L04AC05; TT-20	Interleukin Related	Inflammation/Immunology Cancer
Ustekinumab is an anti-IL-12/IL-23 IgG1κ human monoclonal antibody.

ENUM006	LAG-3	Cancer
ENUM006 is a human monoclonal antibody (mAb) targeting CD223/LAG3 .

Anti-Human/Rat/Fish AChR Antibody (Mab35)	nAChR	Neurological Disease
Anti-Human/Rat/Fish AChR Antibody (Mab35) is an anti-human/rat/fish AChR IgG1 monoclonal antibody. Anti-Human/Rat/Fish AChR Antibody (Mab35) can attack the AChR of neuromuscular junctions. Anti-Human/Rat/Fish AChR Antibody (Mab35) can be used for the construction of myasthenia gravis models .

Etesevimab CB 6; JS016	SARS-CoV Angiotensin-converting Enzyme (ACE)	Infection
Etesevimab (JS016) is a recombinant neutralizing human IgG1 anti-SARS-CoV-2 monoclonal antibody .

DNV-3	LAG-3	Cancer
DNV-3 is a human monoclonal antibody (mAb) targeting CD223/LAG3 .

Dusigitumab MEDI 573	IGF-1R	Others
Dusigitumab (MEDI 573) is a human IgG2λ monoclonal antibody that specifically targets IGF2 and IGF1 .

MLN 591 MLN2704 antibody	PSMA	Cancer
MLN 591 is a human monoclonal antibody (mAb) targeting PSMA. MLN 591 can be used in Prostate cancer research .

ALD306 ALD309	PCSK9	Endocrinology
ALD306 is a human monoclonal antibody (mAb) targeting PCSK9. ALD306 can be used in Hypercholesterolaemia research .

Otelixizumab ChAglyCD3; TRX 4	CD3	Metabolic Disease
Otelixizumab (ChAglyCD3) is an anti-human CD3 monoclonal antibody and can be used for the research of type 1 diabetes .

Cat. No.	Product Name	Type

HY-164153

ADC Control Human IgG1-vcMMAE (solution)	Chromogenic Assays
ADC Control Human IgG1-vcMMAE (solution) is a humanized monoclonal antibody that is an isotype control of ADC human IgG1-vcMMAE and can inhibit tubulin polymerization. The antibody portion is Human IgG1 kappa, Isotype Control (HY-P99001), and the drug-linker conjugate for ADC is vcMMAE (HY-15575) .

HY-164152

ADC Control Human IgG1-Deruxtecan (DAR 4)	Chromogenic Assays
ADC Control Human IgG1-Deruxtecan (DAR 4) is a humanized monoclonal antibody that is an isotype control of ADC human IgG1-Deruxtecan and can inhibit DNA topoisomerase I. The antibody portion is Human IgG1 kappa, Isotype Control (HY-P99001), and the drug-linker conjugate for ADC is Deruxtecan (HY-13631E) .

HY-164152A

ADC Control Human IgG1-Deruxtecan (DAR 8)	Chromogenic Assays
ADC Control Human IgG1-Deruxtecan (DAR 8) is a humanized monoclonal antibody that is an isotype control of ADC human IgG1-Deruxtecan and can inhibit DNA topoisomerase I. The antibody portion is Human IgG1 kappa, Isotype Control (HY-P99001), and the drug-linker conjugate for ADC is Deruxtecan (HY-13631E) .

Cat. No.	Product Name	Target	Research Area

HY-P3203A

DSTYSLSSTLTLSK TFA	TNF Receptor	Inflammation/Immunology
DSTYSLSSTLTLSK TFA is a generic human peptide and can be used for infliximab quantitative detection . Infliximab (Avakine) is a chimeric monoclonal IgG1 antibody that specifically binds to TNF-α.

HY-P3203

DSTYSLSSTLTLSK	Biochemical Assay Reagents	Inflammation/Immunology
DSTYSLSSTLTLSK is a generic human peptide and can be used for infliximab quantitative detection . Infliximab (Avakine) is a chimeric monoclonal IgG1 antibody that specifically binds to TNF-α.

HY-P4025

ELDKWA	HIV	Others
ELDKWA is the highly conserved amino acids on the ecto-domain of gp41. ELDKWA acts as the epitope of a neutralizing monoclonal antibody 2F5 (mAb 2F5) directed against human immunodeficiency virus type 1 .

HY-P11084

WT1 126-134 peptide	MHC	Inflammation/Immunology Cancer
WT1 126-134 peptide is a Wilms' tumor oncogene protein (WT1) peptide (RMFPNAPYL). WT1 126-134 peptide is presented by HLA-A0201 and induces cytotoxic CD8 T cells capable of killing WT1+ positive tumor cells. WT1 126-134 can form stable complexes with the H-2Db (mouse) or HLA-A0201 (human) molecules. WT1 126-134 peptide/HLA-A0201 complex has an extremely high affinity (K_d = 0.2 nM) with the humanized monoclonal antibody (IgG1). WT1 126-134 peptide can be used as a vaccine for T cells or as a target for antibodies .

Cat. No.	Product Name

HY-K0213

Protein A Agarose 3 Publications Verification
MCE Protein A Agarose, a 4% highly cross-linked agarose reagent coupled with recombinant Protein A, effectively purifies mammalian monoclonal and polyclonal antibodies, such as human IgG, IgE, IgM.

HY-K0214

Protein G Agarose 5 Publications Verification
MCE Protein G Agarose, a 4% highly cross-linked agarose reagent coupled with recombinant Protein G, effectively purifies mammalian monoclonal and polyclonal antibodies, such as human IgG3 and rat IgG2a.

Cat. No.	Product Name	Target	Research Area

HY-P99278

Adecatumumab MT 201; Anti-human EPCAM Recombinant antibody	Inhibitory Antibodies	Cancer
Adecatumumab (Anti-Human EPCAM Recombinant Antibody; MT201) is a full human monoclonal antibody of the IgG1 isotype, targeting human EpCAM. Adecatumumab is expressed in almost all adenocarcinomas, and its activity is not dependent of K-Ras status .

HY-P9938

Erenumab AMG-334	CGRP Receptor	Others
Erenumab is a fully human monoclonal antibody. Erenumab inhibits the calcitonin gene–related peptide (CGRP) receptor. Erenumab can be used for the prevention of episodic migraine .

HY-P99514

Zalifrelimab AGEN1884	CTLA-4	Cancer
Zalifrelimab (AGEN1884) is a fully human IgG1 monoclonal antibody targeting CTLA-4 (CTLA-4). Zalifrelimab antagonizes the inhibitory checkpoints of immune cell activation regulated by CTLA-4 signaling .

HY-P99246

Bermekimab MABp1	Interleukin Related	Inflammation/Immunology Cancer
Bermekimab (MABp1) is a human monoclonal antibody targeting interleukin-1α(IL-1α) . Bermekimab can prevent tumor-related inflammation. Bermekimab can be used in the research of atopic dermatitis .

HY-P99474

Bertilimumab CAT 213; iCo-008	CCR	Inflammation/Immunology
Bertilimumab (CAT 213; iCo-008) is a human monoclonal antibody targeting eotaxin-1 (CCL11). Bertilimumab has the potential for allergic disorders research .

HY-P99631

Garadacimab 1 Publications Verification CSL312	Factor Xa	Cardiovascular Disease
Garadacimab (CSL312) is a first-in-class, fully human IgG4 monoclonal antibody targeting activated factor XII (FXIIa). Garadacimab has the potential for hereditary angioedema research .

HY-P9916

Sarilumab Anti-human IL6Rα, human antibody	Interleukin Related	Inflammation/Immunology Cancer
Sarilumab (Anti-Human IL6Rα, Human Antibody) is a human immunoglobulin G1 monoclonal antibody. Sarilumab, a interleukin-6 (IL-6) receptor antagonist, binds to the IL-6 receptor with high affinity and inhibits cis and trans signaling by IL-6, resulting in reduced inflammation. Sarilumab can be used for the research of Rheumatoid arthritis .

HY-P99632

Garetosmab 1 Publications Verification REGN 2477	TGF-β Receptor	Inflammation/Immunology
Garetosmab (REGN 2477) is a fully human IgG4 monoclonal antibody that specifically inhibits activin A. Garetosmab can be used for fibrodysplasia ossificans progressiva (FOP) research .

HY-P99040

Onvatilimab JNJ-61610588; CI-8993; VSTB112	VISTA	Cancer
Onvatilimab (JNJ-61610588) is a human IgG1κ anti-VISTA (V-domain Ig Suppressor of T-cell Activation) monoclonal antibody. Onvatilimab can be used in colorectal cancer research .

HY-P9967

Aducanumab BIIB037	Amyloid-β	Neurological Disease
Aducanumab (BIIB037) is a human monoclonal antibody that selectively targets aggregated amyloid-beta (Aβ). Aducanumab shows brain penetration, and can be used for Alzheimer's disease (AD) research .

HY-P99039

Oleclumab 1 Publications Verification MEDI9447	CD73	Cancer
Oleclumab (MEDI9447) is a human IgG1λ monoclonal antibody targeting CD73 and inhibits the exonuclease activity of the extracellular enzyme CD73. Oleclumab can adjust the composition of bone marrow and lymphoid infiltrating leukocyte populations in the tumor microenvironment and has anti-tumor activity .

HY-P99424

Afasevikumab RG 7624; RO 5553110; NI-1401	Interleukin Related	Inflammation/Immunology
Afasevikumab (RG 7624; RO 5553110; NI-1401) is a fully human monoclonal IgG1κ antibody neutralizing both IL-17A and IL-17F. Afasevikumab has anti-inflammatory activities .

HY-108810

Canakinumab Ilaris; ACZ 885	Interleukin Related	Inflammation/Immunology Cancer
Canakinumab (ACZ885) is a recombinant human *anti-IL-1β* monoclonal antibody. Canakinumab shows IC₅₀ values of 43.6 and 40.8 pM for human and marmoset IL-1β, respectively. The mode of action of canakinumab is based on the neutralization of IL-1β signaling, resulting in suppression of inflammation related to disorders of autoimmune origin .

HY-P9974

Vantictumab 1 Publications Verification OMP-18R5	Wnt	Cancer
Vantictumab (OMP-18R5) is a fully human IgG2 monoclonal antibody. Vantictumab inhibits Wnt pathway signaling by binding to FZD1/2/5/7/8 receptors. Vantictumab can be studied against cancers through direct actions on tumor cells, including CSCs, and effects on the stroma, such as metastatic HER2-negative breast cancer and metastatic pancreatic adenocarcinoma .

HY-P99041

Panitumumab 1 Publications Verification ABX-EGF	EGFR	Cancer
Panitumumab (ABX-EGF) is a fully human IgG2 anti-EGFR monoclonal antibody with anti-tumor activity. Panitumumab inhibits tumor cell proliferation, survival and angiogenesis. Panitumumab can be used in the research of cancers, such as colon cancer .

HY-P99041B

Panitumumab (powder) ABX-EGF (powder)	EGFR	Cancer
Panitumumab (ABX-EGF) (powder) is a fully human IgG2 anti-EGFR monoclonal antibody with anti-tumor activity. Panitumumab (powder) inhibits tumor cell proliferation, survival and angiogenesis. Panitumumab (powder) can be used in the research of cancers, such as colon cancer .

HY-P99184

Abrilumab	Integrin	Infection Inflammation/Immunology Cancer
Abrilumab is a fully **human monoclonal antibody directed against α4β7**. Abrilumab selectively binds the α4β7 integrin heterodimer. Abrilumab can be used for the research of inflammatory bowel disease (IBD) .

HY-P99041A

Panitumumab (anti-EGFR)	EGFR	Cancer
Panitumumab (anti-EGFR) is a fully human IgG2 anti-EGFR monoclonal antibody with anti-tumor activity. Panitumumab (anti-EGFR) inhibits tumor cell proliferation, survival and angiogenesis. Panitumumab (anti-EGFR) can be used in the research of cancers, such as colon cancer .

HY-P9957

Raxibacumab ABthrax	Bacterial	Infection
Raxibacumab (ABthrax) is a human IgG1 monoclonal antibody against Bacillus anthracis protective antigen (PA). Raxibacumab blocks the toxin’s deleterious effects by preventing binding of the protective antigen component of the anthrax toxin to its receptors in host cells, thereby blocking the toxin’s deleterious effects. Raxibacumab can be used for anti-anthrax research .

HY-P991567

VX5 VX5/5261	CXCR	Inflammation/Immunology Cancer
VX5 is a humanized IgG1κ monoclonal antibody inhibitor targeting BCA-1/CXCL13. VX5 significantly inhibits human CXCL13-mediated internalization of CXCR5, blocks both human and mouse CXCL13-dependent B-cells chemotaxis and migration (EC₅₀s for 105 and 253 nM for human tonsillar and pre-B-697-hCXCR5 cells, respectively). VX5 can be used to study autoimmune diseases like multiple sclerosis and arthritis, and cancers like gastric lymphomas and colon cancer .

HY-P991636

AK006	Inhibitory Antibodies	Inflammation/Immunology
AK006 is a humanized IgG1 monoclonal antibody agonist targeting Sialic acid-binding immunoglobulin-like lectin6 (Siglec-6). AK006 potently inhibits IgE-mediated human mast cell activation. AK006 can be used for inflammatory diseases like chronic urticaria (CU) and asthma research .

HY-P991606

TRX585	C-type Lectin-like Receptors (CTLRs)	Infection Inflammation/Immunology Cancer
TRX585 is a humanised anti-immunoglobulin-like transcript 5 (ILT5) monoclonal antibody. TRX585 has a potent immunoregulatory activity. TRX585 significantly activates human T cells and upregulates NKG2D and Fas ligand, followed by enhancing antitumor activity with potent cytotoxicity. TRX585 can be used for viral infections and malignancies research .

HY-P991656

LY-2624587	CXCR Apoptosis p38 MAPK Akt	Cancer
LY-2624587 is a humanized IgG4 monoclonal antibody antagonist targeting CXCR4. LY-2624587 blocks SDF-1/CXCR4 interaction and SDF-1-induced GTP binding. LY-2624587 significantly inhibits cell migration and induces apoptosis in human lymphoma and leukemia cells. LY-2624587 also inhibits CXCR4 and SDF-1 mediated cell signaling including activation of MAPK and AKT. LY-2624587 can be used for human hematological malignancies like acute myeloid leukemia (AML) research .

HY-P99242

Alsevalimab 1 Publications Verification	CD276/B7-H3	Cancer
Alsevalimab is a humanized, afucosylated IgG1 monoclonal antibody against B7-H4. Alsevalimab blocks the binding of the B7-H4 protein to the receptors on the surface of T cells, reversing the immunosuppressive state in the tumor microenvironment, thereby activating the killing effect of T cells on cancer cells. Alsevalimab can be used in combination with Pembrolizumab (HY-P9902), and shows good safety profiles .

HY-P99001

Human IgG1 kappa, Isotype Control 5+ Cited Publications	Inhibitory Antibodies	Inflammation/Immunology Cancer
Human IgG1 kappa, Isotype Control is a human monoclonal antibody that is the isotype control of human IgG1 kappa antibody .

HY-P991206

Human IgG2 lambda, Isotype Control	Inhibitory Antibodies	Inflammation/Immunology
Human IgG2 lambda, Isotype Control, a human monoclonal antibody, is an isotype control for human IgG2λ antibody .

HY-P99002

Human IgG2 kappa, Isotype Control	Inhibitory Antibodies	Inflammation/Immunology
Human IgG2 kappa, Isotype Control, a human monoclonal antibody, is an isotype control for human IgG2κ antibody .

HY-P99509

Zelminemab AMG-301	Adenylate Cyclase	Neurological Disease
Zelminemab (AMG-301) is a humanized monoclonal antibody that inhibits PACAP type I (PAC1) receptor .

HY-P99003

Human IgG4 (S228P) kappa, Isotype Control 5 Publications Verification	Inhibitory Antibodies	Inflammation/Immunology
Human IgG4 (S228P) kappa, Isotype Control, a human-derived monoclonal antibody, is an isotype control for human IgG4κ antibody.

HY-P991451

Anti-ALPP Antibody SGN-ALPV antibody	Phosphatase	Cancer
Anti-ALPP Antibody (SGN-ALPV antibody) is a human monoclonal antibody (mAb) targeting ALPP. Anti-ALPP Antibody can be used in solid tumors research .

HY-P99324

Tomuzotuximab Anti-human EGFR Recombinant antibody; CetuxiMab-GEX, GEXMab52201	EGFR Apoptosis	Cancer
Tomuzotuximab (Anti-Human EGFR Recombinant Antibody) is a fully human glycoengineered IgG1 monoclonal antibody against EGFR. Tomuzotuximab has anticancer effects .

HY-P99526

Vapaliximab 2D10	VAP-1	Inflammation/Immunology
Vapaliximab (2D10) is a monoclonal antibody against human VAP-1 .

HY-P991120

Balertatug	TNF Receptor	Cancer
Balertatug is a human IgG1K antibody targeting CD70. The corresponding isotype control is: Human lgG1 kappa, lsotype Control (HY-P99001) .

HY-P99447

Atidortoxumab	Bacterial	Infection
Atidortoxumab is a human IgG1κ monoclonal antibody that targets Staph aureus alpha toxin .

HY-P9908

Adalimumab 10+ Cited Publications Anti-human TNF-alpha, human antibody	TNF Receptor Bacterial	Inflammation/Immunology Cancer
Adalimumab is a human monoclonal IgG1 antibody targeting tumour necrosis factor α (TNF-α).

HY-P991207

Human IgG1 (L234A/L235A) kappa, Isotype Control	Inhibitory Antibodies	Inflammation/Immunology
Human IgG1 (L234AL235A) kappa, Isotype Control, a human monoclonal antibody, is an isotype control for human IgG1κantibody.

HY-P99232

Indusatumab 5F9 monoclonal antibody	Guanylate Cyclase	Cancer
Indusatumab (5F9 Monoclonal antibody) is a monoclonal antibody against human GUCY2C (Guanylate cyclase 2C). Indusatumab can be used to synthesize ADCs, such as Indusatumab vedotin (HY-P99662). Indusatumab can be used in cancer research .

HY-P991470

Anti-Tenascin C Antibody Neuradiab antibody	Transmembrane Glycoprotein	Cancer
Anti-Tenascin C Antibody (Neuradiab antibody) is a human monoclonal antibody (mAb) targeting Tenascin C. Anti-Tenascin C Antibody can be used in Glioblastoma research. Recommended isotype control: Human IgG1 kappa, Isotype Control (HY-P99001) .

HY-P990096

Human IgG1 lambda2, Isotype Control	Inhibitory Antibodies	Inflammation/Immunology
Human IgG1 lambda2, Isotype Control is a human monoclonal antibody that is the isotype control of human IgG1λ antibody. Isotype control antibodies can help remove non-specific signals from experimental results and assess the accuracy and reliability of the experiment .

HY-P990727

Alextatug	DNA/RNA Synthesis	Inflammation/Immunology
Alextatug is an anti-PABPC1 human IgG1 λ7 monoclonal antibody .

HY-P991379

MG1113A	Tissue Factor Pathway Inhibitor (TFPI)	Others
MG1113A is a human monoclonal antibody (mAb) targeting TFPI. MG1113A can be used in Haemophilia research.

HY-P99457

Balstilimab AGEN2034	PD-1/PD-L1	Inflammation/Immunology Cancer
Balstilimab (AGEN2034) is a fully human monoclonal IgG4 antibody against PD-1 .

HY-P991191

REGN-5054	Transmembrane Glycoprotein	Cancer
REGN5054 is a fully human monoclonal IgG1 antibody that binds specifically to human and cynomolgus CD8 expressed on T cells .

HY-P99329

Vadastuximab Anti-human CD33 Recombinant antibody	Transmembrane Glycoprotein	Cancer
Vadastuximab (Anti-Human CD33 Recombinant Antibody) is a humanized monoclonal antibody targeting CD33. Vadastuximab can be used to synthesize an ADC compound, Vadastuximab talirine .

HY-P99453

Azintuxizumab	ADC Antibody	Cancer
Azintuxizumab is an anti-SLAMF7 human IgG4κ monoclonal antibody. Azintuxizumab can be used in the synthesis of antibody-drug conjugate (ADC), Azintuxizumab vedotin .

HY-P9909

Ustekinumab 3 Publications Verification CNTO-1275; L04AC05; TT-20	Interleukin Related	Inflammation/Immunology Cancer
Ustekinumab is an anti-IL-12/IL-23 IgG1κ human monoclonal antibody.

HY-P991299

ENUM006	LAG-3	Cancer
ENUM006 is a human monoclonal antibody (mAb) targeting CD223/LAG3 .

HY-P990302

Anti-Human/Rat/Fish AChR Antibody (Mab35)	nAChR	Neurological Disease
Anti-Human/Rat/Fish AChR Antibody (Mab35) is an anti-human/rat/fish AChR IgG1 monoclonal antibody. Anti-Human/Rat/Fish AChR Antibody (Mab35) can attack the AChR of neuromuscular junctions. Anti-Human/Rat/Fish AChR Antibody (Mab35) can be used for the construction of myasthenia gravis models .

HY-P99347

Etesevimab CB 6; JS016	SARS-CoV Angiotensin-converting Enzyme (ACE)	Infection
Etesevimab (JS016) is a recombinant neutralizing human IgG1 anti-SARS-CoV-2 monoclonal antibody .

HY-P991298

DNV-3	LAG-3	Cancer
DNV-3 is a human monoclonal antibody (mAb) targeting CD223/LAG3 .

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HY-P700257

	Ki67/MKI67 Protein, Human (His) Proliferation marker protein Ki-67; Antigen identified by monoclonal antibody Ki-67 (Antigen KI-67; Antigen Ki67); MKI67	Human	E. coli
	Ki67/MKI67 is localized on mitotic chromosomes and maintains its dispersion during nuclear envelope disassembly. It covers a large portion of the chromosome surface and prevents chromatin from collapsing into clumps. Ki67/MKI67 Protein, Human (His) is the recombinant mouse-derived Ki-67(MKI67) protein, expressed by E. coli , with N-6*His labeled tag.

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HY-P85009

	CD82 Antibody (YA4701) 4F9 antibody; Antigen detected by monoclonal and antibody IA4 antibody; C33 antibody; C33 antigen antibody; CD 82 antibody; CD82 antibody; CD82 antigen antibody; CD82 molecule antibody; CD82_human antibody; GR 15 antibody; GR15 antibody; IA 4 antibody; IA4 antibody; Inducible membrane protein antibody; Inducible membrane protein R2 antibody; KAI 1 antibody; KAI1 antibody; Kangai 1; suppression of tumorigenicity 6; prostate; CD82 antigen; R2 leukocyte antigen; antigen detected by monoclonal and antibody IA4; antibody; Kangai 1 antibody; Kangai1 antibody; Leukocyte surface antigen R2 antibody; Metastasis suppressor Kangai 1 antibody; Metastasis suppressor Kangai-1 antibody; Metastasis suppressor Kangai1 antibody; Prostate cancer antimetastasis gene KAI1 antibody; R2 antibody; R2 leukocyte antigen antibody; SAR 2 antibody; SAR2 antibody; ST 6 antibody; ST6 antibody; Suppression of tumorigenicity 6 antibody; Suppression of tumorigenicity 6 prostate antibody; Suppressor of tumorigenicity 6 antibody; Suppressor of tumorigenicity 6 protein antibody; Tetraspanin 27 antibody; Tetraspanin-27 antibody; Tetraspanin27 antibody; Tspan 27 antibody; Tspan-27 antibody; Tspan27 antibody; CD82 nanobody;	ELISA, FC	Human
	CD82 Antibody (YA4701) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to CD82.

HY-P84998

	CD56 Antibody (YA4690) antigen MSK39 identified by monoclonal 5.1H11; antigen recognized by monoclonal 5.1H11; CD56; cell adhesion molecule; neural; 1; MSK 39; MSK39; N-CAM-1; NCAM 1; NCAM; NCAM C; NCAM-1; NCAM1; NCAM1_human; NCAMC; Neural cell adhesion molecule 1; Neural cell adhesion molecule NCAM; OTTHUMP00000235666; CD56 nanobody;	ELISA, FC	Human
	CD56 Antibody (YA4690) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to CD56.

HY-P85951

	CD56 Antibody (YA5643) antigen MSK39 identified by monoclonal 5.1H11; antigen recognized by monoclonal 5.1H11; CD56; cell adhesion molecule, neural, 1; MSK 39; MSK39; N-CAM-1; NCAM 1; NCAM; NCAM C; NCAM-1; NCAM1; NCAM1_human; NCAMC; Neural cell adhesion molecule 1; Neural cell adhesion molecule NCAM; OTTHUMP00000235666	IHC-P, WB, ICC/IF, ELISA	Human, Mouse, Rat
	CD56 Antibody (YA5643) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD56.

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HY-153084

CD19 CAR mRNA (Mouse)		mRNA
CD19 CAR mRNA (Mouse) is an mRNA designed based on FMC63-28Z. FMC63–28Z had a scFv from a murine antibody (FMC63, a recombinant monoclonal antibody specific for human CD19), hinge, transmembrane, and cytoplasmic domains from CD28, and a CD3ζ domain. CD19 CAR mRNA can trigger transitory expression of CAR, allowing T cells to be targeted without permanent genetic modification. CD19 CAR mRNA targets CD19 which is a transmembrane glycoprotein primarily expressed on B lymphocytes and is important in B cell activation. CD19 CAR mRNA can be studied in cancer research such as lymphoma and leukemia .

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