2. Immunology/Inflammation
  3. C-type Lectin-like Receptors (CTLRs)
  4. TRX585

TRX585 is a humanised anti-immunoglobulin-like transcript 5 (ILT5) monoclonal antibody. TRX585 has a potent immunoregulatory activity. TRX585 significantly activates human T cells and upregulates NKG2D and Fas ligand, followed by enhancing antitumor activity with potent cytotoxicity. TRX585 can be used for viral infections and malignancies research.

For research use only. We do not sell to patients.

TRX585 Chemical Structure

TRX585 Chemical Structure

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Description

TRX585 is a humanised anti-immunoglobulin-like transcript 5 (ILT5) monoclonal antibody. TRX585 has a potent immunoregulatory activity. TRX585 significantly activates human T cells and upregulates NKG2D and Fas ligand, followed by enhancing antitumor activity with potent cytotoxicity. TRX585 can be used for viral infections and malignancies research[1].

IC50 & Target

LILRB3/CD85a
Gene ID

102725035  [NCBI]

Accession

AAI04994.1
Target

LILRB3/CD85a
Application

ELISA, FACS, Functional assay
Conjugated

Unconjugated
Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.
SMILES

N/A
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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TRX585 Related Classifications

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

TRX585TRX 585TRX-585C-type Lectin-like Receptors (CTLRs)Immunoglobulin-like transcript 5ILT5antitumorImmunoregulatoryMonoclonal antibodyHuman T cellsViral infectionsMalignanciesInhibitorinhibitorinhibit

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