1. Immunology/Inflammation
  2. PSMA
  3. Anti-PSMA Antibody

Anti-PSMA Antibody  (Synonyms: ARX517 antibody)

Cat. No.: HY-P991204 Purity: 96.31%
Technical Support

Anti-PSMA Antibody (ARX517 antibody) is a humanized IgG1 monoclonal antibody that targets PSMA. Anti-PSMA Antibody is the antibody part of the ADC molecule ARX517. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001).

For research use only. We do not sell to patients.

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This product is a controlled substance and not for sale in your territory.

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Description

Anti-PSMA Antibody (ARX517 antibody) is a humanized IgG1 monoclonal antibody that targets PSMA. Anti-PSMA Antibody is the antibody part of the ADC molecule ARX517. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001)[1].

Isotype

Human IgG1 kappa (without para-acetyl phenylalanine (pAF))

Recommend Isotype Controls
Species Reactivity

Human

IC50 & Target

PSMA

In Vitro

ADC antibodies act as the navigation system of ADC drugs and are primarily responsible for delivering payloads to target cells.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Gene ID

2346  [NCBI]

Accession

Q04609-1

Application

ELISA, FACS, Functional assay

Conjugated

Unconjugated

Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.

Molecular Weight

144.82 kDa

Appearance

Liquid

Color

Colorless to light yellow

SMILES

N/A

Shipping

Shipping with dry ice.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Biological Activity
  • Immobilized PSMA-His can bind Anti-PSMA Antibody. The EC50 for this effect is 59.48 ng/mL.
Purity & Documentation
References
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Anti-PSMA Antibody
Cat. No.:
HY-P991204
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