2. Anti-infection Metabolic Enzyme/Protease
  3. SARS-CoV Angiotensin-converting Enzyme (ACE)
  4. Etesevimab

Etesevimab  (Synonyms: CB 6; JS016)

Cat. No.: HY-P99347 Purity: 98.76%
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Etesevimab (JS016) is a recombinant neutralizing human IgG1 anti-SARS-CoV-2 monoclonal antibody.

For research use only. We do not sell to patients.

CAS No. : 2423948-94-9

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Description

Etesevimab (JS016) is a recombinant neutralizing human IgG1 anti-SARS-CoV-2 monoclonal antibody[1].

Isotype

Human IgG1 kappa
Recommend Isotype Controls
IC50 & Target

Severe acute respiratory syndrome coronavirus 2
In Vitro

Etesevimab (JS016) binds the spike protein with a Kd of 6.45 nM and blocks spike protein attachment to the human angiotensin converting enzyme 2 (ACE2) receptor with an IC50 value of 0.32 nM (0.046 μg/mL)[1].
Etesevimab blocks viral cell fusion to prevent SARS-CoV-2 invasion of human cells and inhibits viral replication[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Etesevimab Related Antibodies
Clinical Trial
Accession
Application

ELISA, FACS, Functional assay
Conjugated

Unconjugated
Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.
Molecular Weight

145.18 kDa

CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Etesevimab]
Shipping

Shipping with dry ice.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • Human IgG1 kappa
Purity & Documentation
References
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Etesevimab Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Etesevimab2423948-94-9CB 6 JS016CB6CB-6JS016JS 016JS-016SARS-CoVAngiotensin-converting Enzyme (ACE)SARS coronavirusInhibitorinhibitorinhibit

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