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EC330 is a leukemia inhibitory factor (LIF) inhibitor. EC330 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
EC359 is a potent, selective, high affinity and orally active leukemia inhibitory factor receptor (LIFR) inhibitor with a Kd of 10.2 nM, which directly interacts with LIFR to effectively block LIF/LIFR interactions . EC359 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
EC0489, a conjugate of folic acid and desacetyl vinblastine hydrazide, is a high-affinity ligand for the folate receptor (FR). Refractory or metastatic Tumor . Small molecule-agent conjugate (SMDC) .
EC1167 is the linker for EC1169. EC1169 is prostate-specific membrane antigen targeting-tubulysin conjugate. EC1169 has the potential to treat recurrent metastatic, castration-resistant prostate cancer (MCRPC) .
EC33 is a selective aminopeptidase A (APA) inhibitor. EC33 blocks the pressor response of exogenous Ang II. EC33 does not cross the blood-brain barrier. EC33 has the potential for salt-dependent model of hypertension research .
EC1454 is a peptide compound with anticancer activity that targets folate receptor-expressing cancers. EC1454 is a folate-tubulysin conjugate that can be used to prepare drug delivery conjugates for targeted therapy .
EC144 is a potent and selective inhibitor of heat shock protein 90 (Hsp90) with an IC50 of 1.1 nM. EC144 inhibits tumor growth and causes partial tumor regressions. EC144 has the potential for the research of cancer diseases . EC144 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
EC1167 hydrochloride is the linker for EC1169. EC1169 is prostate-specific membrane antigen targeting-tubulysin conjugate. EC1169 hydrochloride has the potential to treat recurrent metastatic, castration-resistant prostate cancer (MCRPC) .
EC-17 disodium salt is a folate receptor alpha (FRα) targeting contrast agent with fluorescent properties in the visible light spectrum. The EC-17 maximum excitation and emission wavelengths are 490 nm and 520 nm, respectively .
Mosedipimod is a monoacetyldiaglyceride that can be isolated from Cervus nippon Temminck. Mosedipimod is an orally active Toll-Like Receptor signaling inhibitor. Mosedipimod attenuates airway infammation by reducing myeloperoxidase expression in lung tissue. Mosedipimod is used in chronic obstructive pulmonary disease research .
EC5026 (BPN-19186) is a first-in-class, non-opioid and orally active soluble Epoxide Hydrolase (sEH) inhibitor. EC5026 shows efficacy for inflammatory and neuropathic pain .
Folate-FITC (EC-17) is a folate receptor alpha (FRα) targeting contrast agent with fluorescent properties in the visible light spectrum. The Folate-FITC maximum excitation and emission wavelengths are 490 nm and 520 nm, respectively .
Rennin, also known as Chymosin, is a pepsin-related proteolytic enzyme synthesized by cells in the stomach of certain animals that efficiently converts liquid milk into a semi-solid, allowing it to remain in the stomach for longer. The natural substrate of Rennin is K-casein, which is specifically cleaved at the peptide bond between amino acid residues 105 and 106, phenylalanine and methionine, and is widely used in cheese production .
Subtilisin (EC 3.4.21.14) is a bacterial serine protease. Subtilisin induces Apoptosis. Subtilisin stimulates the expression of pro-allergic cytokines (IL-1α, IL-33). Subtilisin induces prototypic allergic lung inflammation. Subtilisin exhibits anticancer activity against breast and colon cancer. Subtilisin shows antifouling activity. Subtilisin can be used as a detergent additive .
Pepsin is the major pig and human gastric proteases, it is a pepsin-like minor gastric proteolytic enzymes. Pepsin contributes to proteolysis of food proteins in the vertebrate stomach .
Maltose phosphorylase is a dimerase which catalyzes the transformation of maltose and inorganic phosphate into β-D-glucose-1-phosphate and glucose. Maltose phosphorylases have been classified in family 65 of the glycoside hydrolases .
Pectinase (EC 3.2.1.15) is a mixed enzymes that hydrolyze pectic substances, it mostly presents in microorganisms and higher plants. Pectinase is involved in the metabolism of the cell wall as well as in the growth of the cell, senescence, ripening of fruits, pathogenesis and abscission process .
Collagenase, Type I is a microbially derived matrix metalloproteinases (MMPs) and zinc peptidase. Collagenase, Type I breaks down collagens 1, 3, 7, 8, 10, gelatin, proteoglycans, aggrecan .
Chymotrypsin (Chymotrypsin A) is a serine protease produced by the pancreas. Chymotrypsin cleaves protein chains at the carboxyl side of aromatic amino acids .
Alcohol dehydrogenase, Saccharomyces cerevisiae is a dimeric protein in the cytosol of cells. Alcohol dehydrogenase, the key enzyme for alcohol consumption in the body, is the highest expressed in the liver and participates in the detoxification mechanism of environmental alcohol .
Carboxypeptidase B, Porcine pancreas (EC 3.4.2.2) is a peptide exonuclease that can specifically degrade peptide chains. Carboxypeptidase B is progressively degraded from the C-terminal to release free amino acids. Carboxypeptidase B hydrolyzes only peptide bonds with basic amino acids (such as arginine and lysine) as C-terminal residues .
Carboxypeptidase C is a carboxypeptidase, is often used in biochemical studies. Carboxypeptidase C removes COOH-terminal lysine, arginine, and proline, as well as all other neutral, aliphatic, aromatic, and the acidic protein amino acids of a peptide chain .
Carbonic anhydrase, Bovine erythrocytes (EC 4.2.1.1) is ubiquitous zinc-containing metalloenzyme present in prokaryotes and eukaryotes. Carbonic anhydrase can catalyze reversible conversion of carbon dioxide to bicarbonate and protons. Carbonic anhydrase can be used for the research of cancer, glaucoma, obesity and epilepsy .
(R)-Alcohol dehydrogenase (E.C. 1.1.1.2) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Carboxypeptidase A, Bovine pancreas (EC 3.4.2.1) is a zinc-containing metalloprotease, is often used in biochemical studies. Carboxypeptidase A catalyzes the hydrolysis of the peptide bonds that are adjacent to the C-terminal end of a polypeptide chain. Carboxypeptidase A is a prototypical enzyme for metalloproteases that plays important roles in biological systems .
Malate dehydrogenase (EC 1.1.1.37) (MDH) catalyzes the mutual conversion of oxaloacetate and malate, and is associated with the oxidation/reduction of dinucleotide coenzymes .
Glutathione Peroxidase (GSH-Px; EC 1.11.1.9) belongs to the peroxidase family and is commonly used in biochemical research. Glutathione Peroxidase can catalyze reduced glutathione (GSH) to form a disulfide bridge with another glutathione molecule, convert it into oxidized glutathione (GSSG), and react with hydrogen peroxide or lipid peroxide reaction, reducing it to H2O. Glutathione Peroxidase is an effective antioxidant against oxidative stress .
Acetylcholinesterase, Fly head (ACHE; EC 3.1.1.7) is a cholinergic enzyme mainly found in neuromuscular junctions and cholinergic type chemical synapses used in biochemical research. Acetylcholinesterase, Fly head catalyzes the breakdown or hydrolysis of acetylcholine and some other choline esters that act as neurotransmitters into acetate and choline. Acetylcholinesterase, Fly head's main role is to terminate neuronal transmission and signaling between synapses to prevent ACh spread and activation of nearby receptors .
Pepsin (MS Grade) is the major pig and human gastric proteases, it is a pepsin-like minor gastric proteolytic enzymes. Pepsin (MS Grade) contributes to proteolysis of food proteins in the vertebrate stomach .
Glutathione reductase, baker's yeast (EC 1.6.4.2) is a reductase. Glutathione reductase, baker's yeast eliminates intracellular ROS. Glutathione reductase, baker's yeast reduces oxidized glutathione (GSSG) to reduced glutathione (GSH) using NADPH as an electron donor. Glutathione reductase, baker's yeast exerts antioxidant activity. Glutathione reductase is mainly used to study diseases associated with oxidative stress, such as Parkinson's disease and sickle cell anemia .
Elastase, Porcine pancreas (EC 3.4.21.36) is a single polypeptide chain of 240 amino acid residues, derived from pig pancreas. Elastase, Porcine pancreas is a serine protease that can hydrolyze proteins and polypeptide. Elastase from porcine pancreas can induce emphysema in hamsters .
α-Galactosidase, Aspergillus niger (EC 3.2.1.22), that is, α-galactosidase, is a glycoside hydrolase that widely exists in animals, plants and microorganisms, and is often used in biochemical research. α-Galactosidase catalyzes the hydrolysis of α-1,6-linked terminal galactose residues, including galactooligosaccharides, galactomannans, and galactolipids. Catalyzes many catabolic processes including cleavage of glycoproteins, glycolipids and polysaccharides .
N-Acetylgalactosamine-6-Sulfatase (GALNS) is a potential general biomarker for multiple malignancies (such as lung cancer, breast cancer, head and neck cancer, etc.). N-Acetylgalactosamine-6-Sulfatase deficiency causes mucopolysaccharidosis type IVA (MPS IVA), also known as Morquio A syndrome. N-Acetylgalactosamine-6-Sulfatase can be used in MPS IVA as well as cancer research .
Fucosyltransferase 7 (FUT7) is a golgi stack membrane protein. Fucosyltransferase 7catalyzes the final fucosylation step in the synthesis of Lewis antigens and generates a unique glycosylated product sialyl Lewis X (sLeX). Fucosyltransferase 7 catalyzes alpha-1,3 glycosidic linkages involved in the expression of sialyl Lewis X antigens .
Fucosyltransferase 11 (EC:2.4.1.-, FUT11) links alpha-l-fucose onto conalbumin glycopeptides and biantennary N-glycan acceptors. Fucosyltransferase 11 plays an important role in cancer .
Cholinesterase, Horse serum infers to acetylcholinesterase (AChE) and butyryl cholinesterase (BChE). AChE and BChE catalyze the hydrolysis of 6-MAM to morphine .
β-Galactosidase (EC 3.2.1.23) is a glycoside hydrolase that hydrolyzes the β-glycosidic bonds formed between galactose and its organic moieties. In E.coli, the lacZ gene is the structural gene of β-galactosidase, which can be used as part of the induction system lac operon. β-Galactosidase can hydrolyze lactose to form glucose and galactose, and enter glycolysis; it can also catalyze the transgalactosylation of lactose into allolactose; allolactose can be cracked into monosaccharides .
Fucosyltransferase 9 (EC:2.4.1.152, FUT9) catalyzes the last step in the biosynthesis of Lewis antigen, the addition of a fucose to precursor polysaccharides. Fucosyltransferase 9 synthesizes the LeX oligosaccharide (CD15) .
Carboxypeptidase B (MS grade) is a peptide exonuclease that can specifically degrade peptide chains. Carboxypeptidase B (MS grade) is progressively degraded from the C-terminal to release free amino acids. Carboxypeptidase B (MS grade) hydrolyzes only peptide bonds with basic amino acids (such as arginine and lysine) as C-terminal residues .
α-L-Fucosidase, Microorganism (EC 3.2.1.51) is an enzyme that catalyzes the chemical reaction. Serum activity of α-L-Fucosidase, Microorganism, a lysosomal enzyme present in all mammalian cells, has been proposed as a marker of hepatocellular carcinoma (HCC) .
Aspartate aminotransferase, Genetically engineered bacteria (EC 2.6.1.1) (AST) is a transaminase enzyme, is often used in biochemical studies. Aspartate aminotransferase catalyzes aspartate and alpha-ketoglutarate converts to oxaloacetate and glutamate. Aspartate aminotransferase can be found in cerebrospinal fluid, exudates, and transudates .
Tyrosylprotein Sulfotransferase 2 (TPST-2) is a subtype of TPST. Tyrosylprotein Sulfotransferase is a 54- to 50-kDa integral membrane glycoprotein of the trans-Golgi network found in essentially all tissues investigated, catalyzing the tyrosine O-sulfation of soluble and membrane proteins passing through this compartment .
RNase A, Bovine pancreas (Ribonuclease A) cleaves the 3' end of RNA to pyrimidine and actively cleaves RNA at each pyrimidine residue. RNase A, bovine pancreas catalyzes the hydrolysis of single-stranded RNA in the absence of metal ions or cofactors .
N-Acetylglucosaminyltransferase1 (EC:2.4.1.101, MGAT1) shows typical features of a type II transmembrane protein. N-Acetylglucosaminyltransferase1 is believed to be essential for normal embryogenesis .
Endo-1,4-β-xylanase (Xylanase) is an arabinoxylan (AX) degrading enzyme and a glycoside hydrolase, is often used in biochemical studies. Endo-1,4-β-xylanase cleaves the β-xylosidic bond between two d-xylopyranosyl residues linked in β-(1,4) .
Chymotrypsin (Chymotrypsin A) (MS grade) is a serine protease produced by the pancreas. Chymotrypsin (MS grade) cleaves protein chains at the carboxyl side of aromatic amino acids .
Glucosaminyl (N-acetyl) Transferase 2 (EC:2.4.1.150, GCNT2, GCNT5, NACGT1, N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase, N-acetylglucosaminyltransferase, IGNT) is responsible for formation of the blood group I antigen and plays an important role in cancer .
Protein O-Fucosyltransferase 1 (EC:2.4.1.221; POFUT1) is a Glycosyltransferase containing the cysteine-rich motifs as the acceptor sugar and GDP-fucose as the donor .
Protein O-Glucosyltransferase 1 is a glucosyltransferase. Protein O-Glucosyltransferase 1 modifies Notch signaling by adding glucose to serine residues in Notch .
Fucosyltransferase 5 (EC:2.4.1.65, Fucosyltransferase 5, Fucosyltransferase V) is responsible for the terminal step in the synthesis of Lex, sialy-Lex, and Lea antigens .
alpha-1,3-N-Acetylgalactosaminyltransferase (Pm1138) (EC 2.4.1.40(Pm1138)), also namely the ABO system transferase with glycosyl transferase activity .
Carbohydrate Sulfotransferase 4 (EC:2.8.2.-) can catalyze sulphate transfer to the hydroxyl group at C-6 position of the non-reducing GlcNAc residue within O-linked mucin-type glycans .
Fucosyltransferase 8 (EC:2.4.1.68; FUT8; α1-6FucT) is a glycosyl transferase and catalyzes the transfer of a fucose residue from GDP-fucose to the innermost N-acetylglucosamine residue of N-glycans .
Heparan Sulfate 3-O-Sulfotransferase 1 is a sulfotransferase. Heparan Sulfate 3-O-Sulfotransferase controls cellular production of the anticoagulant heparan sulfate related structure .
α-1,4-N-Acetylglucosaminyltransferase 4 (EC 2.4.1, A4GNT) catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans and suppresses H. pylori growth .
β-1,4-Galactosyltransferase 7 has exclusive specificity for the donor substrate UDP-galactose and all transfer galactose in a β-1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. .
β-1,3-N-Acetylglucosaminyltransferase 4 (EC:2.4.1.149, B3GNT4) is involved in the synthesis of poly-N-acetyllactosamine and has activity for type 2 oligosaccharides .
beta-1,4-Glucuronyltransferase 1 is a glucosyltransferase. beta-1,4-Glucuronyltransferase 1 transfers glucuronic acid towards both α and β anomers of xylose .
ST6 Sialyltransferase 1 (EC:2.4.3.3, ST6GALNAC1, SIAT7A, Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1)? transfers a sialic acid, N-acetylneuraminic acid (NeuAc), in an alpha-2,6 linkage to O-linked GalNAc residues. ST6 Sialyltransferase 1 plays an important role in cancer .
I3MT-3 (HMPSNE) is a potent, selective, and cell-membrane permeable inhibitor of 3-Mercaptopyruvate sulfurtransferase (3MST) (IC50=2.7 μM). I3MT-3 is inactive for other H2S/sulfane sulfur-producing enzymes.?I3MT-3 targets a persulfurated cysteine residue located in the active site of 3MST .
Salicylate hydroxylase, Microorganism (EC 1.14.13.1) is a flavin-dependent monooxygenase. Salicylate hydroxylase, Microorganism catalyzes the decarboxylative hydroxylation of salicylate into catechol in the naphthalene degradation pathway in Pseudomonas putida G7. Salicylate hydroxylase, Microorganism has potential biocatalytic applications .
(Rac)-EC5026 ((Rac)-BPN-19186) is a potent piperidine inhibitor of soluble epoxide hydrolase (sEH) extracted from patent WO2019156991A1, page 39, has a Ki of 0.06 nM. (Rac)-EC5026 can be used for the research of Parkinson's disease and dementia with Lewy Bodies (DLB) .
Haloxyfop is an aryloxyphenoxypropionic acid herbicide and is widely used in grass weeds in broad-leaf crops . Haloxyfop inhibits the acetyl coenzyme A carboxylase (EC 6.4.1.2) from corn seedling chloroplasts with an IC50 of 0.5 μM, but has no effect on this enzyme in pea .
Haloxyfop (Standard) is the analytical standard of Haloxyfop. This product is intended for research and analytical applications. Haloxyfop is an aryloxyphenoxypropionic acid herbicide and is widely used in grass weeds in broad-leaf crops . Haloxyfop inhibits the acetyl coenzyme A carboxylase (EC 6.4.1.2) from corn seedling chloroplasts with an IC50 of 0.5 μM, but has no effect on this enzyme in pea .
Leucine dehydrogenase, Microorganism (EC 1.4.1.9) can be purified from Bacillus spheroides. Leucine dehydrogenase catalyzed the oxidative deamination of L-leucine, L-valine, L-isoleucine, L-norvaline, L-alpha-aminobutyrate, and L-norleucine, and the reductive amination of their keto analogues .
Hydroxysafflor yellow A (Standard) is the analytical standard of Hydroxysafflor yellow A. This product is intended for research and analytical applications. Hydroxysafflor yellow A (Safflomin A) is a natural product of flavonoids isolated from safflower. Hydroxysafflor yellow A can inhibit cell proliferation and promote apoptosis through the autophagy pathway. Hydroxysafflor yellow A has anti-inflammatory, antioxidant and antitumor effects. Hydroxysafflor yellow A can be used in the study of cardiovascular disease .
Hydroxysafflor yellow A (Safflomin A) is a natural product of flavonoids isolated from safflower. Hydroxysafflor yellow A can inhibit cell proliferation and promote apoptosis through the autophagy pathway. Hydroxysafflor yellow A has anti-inflammatory, antioxidant and antitumor effects. Hydroxysafflor yellow A can be used in the study of cardiovascular disease .
Retinoic acid (Vitamin A acid) (GMP) is Retinoic acid (HY-14649) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Retinoic acid is an agonist of RAR nuclear receptors .
Tranylcypromine hydrochloride (SKF 385 hydrochloride) is an irreversible inhibitor of lysine-specific demethylase 1 (LSD1/BHC110) and monoamine oxidase (MAO). Tranylcypromine hydrochloride inhibits LSD1, MAO A and MAO B with IC50s of 20.7, 2.3 and 0.95 μM, respectively. Tranylcypromine hydrochloride can be used for the research of depression .
Retinoic acid (Vitamin A acid) (GMP) is Retinoic acid (HY-14649) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Retinoic acid is an agonist of RAR nuclear receptors .
Chymotrypsin (Chymotrypsin A) is a serine protease produced by the pancreas. Chymotrypsin cleaves protein chains at the carboxyl side of aromatic amino acids .
N-Acetylglucosaminyltransferase III (EC:2.4.1.144 MGAT3) transfers a GlcNAc residue to the beta-linked mannose of the trimannosyl core of N-linked oligosaccharides and produces a bisecting GlcNAc .
Arylsulfatase G is a lysosomal sulfatase. Arylsulfatase G has a high degree of sequence similarity with all sulphatases and in particular with arylsulphatases. Arylsulfatase G can be used for the research of metabolic .
N-Acetylgalactosamine-6-Sulfatase (GALNS) is a potential general biomarker for multiple malignancies (such as lung cancer, breast cancer, head and neck cancer, etc.). N-Acetylgalactosamine-6-Sulfatase deficiency causes mucopolysaccharidosis type IVA (MPS IVA), also known as Morquio A syndrome. N-Acetylgalactosamine-6-Sulfatase can be used in MPS IVA as well as cancer research .
Fucosyltransferase 7 (FUT7) is a golgi stack membrane protein. Fucosyltransferase 7catalyzes the final fucosylation step in the synthesis of Lewis antigens and generates a unique glycosylated product sialyl Lewis X (sLeX). Fucosyltransferase 7 catalyzes alpha-1,3 glycosidic linkages involved in the expression of sialyl Lewis X antigens .
Fucosyltransferase 11 (EC:2.4.1.-, FUT11) links alpha-l-fucose onto conalbumin glycopeptides and biantennary N-glycan acceptors. Fucosyltransferase 11 plays an important role in cancer .
Fucosyltransferase 9 (EC:2.4.1.152, FUT9) catalyzes the last step in the biosynthesis of Lewis antigen, the addition of a fucose to precursor polysaccharides. Fucosyltransferase 9 synthesizes the LeX oligosaccharide (CD15) .
Tyrosylprotein Sulfotransferase 2 (TPST-2) is a subtype of TPST. Tyrosylprotein Sulfotransferase is a 54- to 50-kDa integral membrane glycoprotein of the trans-Golgi network found in essentially all tissues investigated, catalyzing the tyrosine O-sulfation of soluble and membrane proteins passing through this compartment .
N-Acetylglucosaminyltransferase1 (EC:2.4.1.101, MGAT1) shows typical features of a type II transmembrane protein. N-Acetylglucosaminyltransferase1 is believed to be essential for normal embryogenesis .
Glucosaminyl (N-acetyl) Transferase 2 (EC:2.4.1.150, GCNT2, GCNT5, NACGT1, N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase, N-acetylglucosaminyltransferase, IGNT) is responsible for formation of the blood group I antigen and plays an important role in cancer .
Protein O-Fucosyltransferase 1 (EC:2.4.1.221; POFUT1) is a Glycosyltransferase containing the cysteine-rich motifs as the acceptor sugar and GDP-fucose as the donor .
Carbohydrate Sulfotransferase 5 (EC:2.8.2.-) can catalyze sulphate transfer to position 6 of non- GlcNAc residues and O-linked sugars of mucin-type acceptors .
Lysosomal α-mannosidase (EC:3.2.1.24; MAN2B1; LAMAN) is an exoglycosidase that hydrolyzes α-mannosidic linkages of mannoglycans. Lysosomal α-mannosidase can be used in the study of α-mannosidosis .
Carbohydrate Sulfotransferase 2 (EC:2.8.2.-) can catalyze sulphate transfer to position 6 of non-reducing GlcNAc residues within keratan-like structures on N-linked glycans and within mucin-associated glycans .
Protein O-Glucosyltransferase 1 is a glucosyltransferase. Protein O-Glucosyltransferase 1 modifies Notch signaling by adding glucose to serine residues in Notch .
Carbohydrate Sulfotransferase 10 (EC:2.8.2.-) can catalyze sulphate transfer to position 3 of terminal glucuronic acid of both protein- and lipid-linked oligosaccharides .
Glucosaminyl (N-acetyl) Transferase 1 ( EC:2.4.1.102, GCNT1) is essential to the formation of Gal beta 1-3(GlcNAc beta 1-6)GalNAc structures and the core 2 O-glycan branch and play an important role in cancer .
Fucosyltransferase 5 (EC:2.4.1.65, Fucosyltransferase 5, Fucosyltransferase V) is responsible for the terminal step in the synthesis of Lex, sialy-Lex, and Lea antigens .
Carbohydrate Sulfotransferase 4 (EC:2.8.2.-) can catalyze sulphate transfer to the hydroxyl group at C-6 position of the non-reducing GlcNAc residue within O-linked mucin-type glycans .
Carbohydrate Sulfotransferase 7 (EC:2.8.2.17) can catalyze sulphate transfer to position 6 of non- GlcNAc residues and to position 6 of the GalNAc residue of chondroitin .
ST6 Gal Sialyltransferase 2 (EC:2.4.3.1, ST6GAL2) catalyzes the transfer of sialic acid from CMP to an oligosaccharide substrate. ST6 Gal Sialyltransferase 2 plays an important role in schizophrenic research .
Fucosyltransferase 8 (EC:2.4.1.68; FUT8; α1-6FucT) is a glycosyl transferase and catalyzes the transfer of a fucose residue from GDP-fucose to the innermost N-acetylglucosamine residue of N-glycans .
Heparan Sulfate 3-O-Sulfotransferase 1 is a sulfotransferase. Heparan Sulfate 3-O-Sulfotransferase controls cellular production of the anticoagulant heparan sulfate related structure .
α-1,4-N-Acetylglucosaminyltransferase 4 (EC 2.4.1, A4GNT) catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans and suppresses H. pylori growth .
β-1,4-Galactosyltransferase 7 has exclusive specificity for the donor substrate UDP-galactose and all transfer galactose in a β-1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. .
β-1,3-N-Acetylglucosaminyltransferase 4 (EC:2.4.1.149, B3GNT4) is involved in the synthesis of poly-N-acetyllactosamine and has activity for type 2 oligosaccharides .
N-Deacetylase/N-Sulfotransferase 2 is a sulfotransferase. N-Deacetylase/N-Sulfotransferase 2 synthesizes serglycin-bound heparin chains in mast cells .
beta-1,4-Glucuronyltransferase 1 is a glucosyltransferase. beta-1,4-Glucuronyltransferase 1 transfers glucuronic acid towards both α and β anomers of xylose .
ST3 beta-Gal alpha-2,3-Sialyltransferase 2 (EC:2.4.3.4, ST3GAL2) catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates .
Heparan Sulfate Glucosamine 3-O-Sulfotransferase 3 is a sulfotransferase. Heparan Sulfate Glucosamine 3-O-Sulfotransferase 3 is important in heparan sulfate biosynthesis .
ST6 Sialyltransferase 1 (EC:2.4.3.3, ST6GALNAC1, SIAT7A, Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1)? transfers a sialic acid, N-acetylneuraminic acid (NeuAc), in an alpha-2,6 linkage to O-linked GalNAc residues. ST6 Sialyltransferase 1 plays an important role in cancer .
ST3 beta-Gal alpha-2,3-Sialyltransferase 6 (EC:2.4.99., ST3GAL6; SIAT10, Type 2 lactosamine alpha-2,3-sialyltransferase) transfer sialic acid from the activated cytidine 5'-monophospho-N-acetylneuraminic acid to terminal positions on sialylated glycolipids (gangliosides) or to the N- or O-linked sugar chains of glycoproteins. ST3 beta-Gal alpha-2,3-Sialyltransferase 6 play an important role in cancer .
Retinoic acid (Vitamin A acid) (GMP) is Retinoic acid (HY-14649) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Retinoic acid is an agonist of RAR nuclear receptors .
Anti-SLAMF6 Antibody (h20F3ec) (SGN-CD352A antibody) is a human-derived antibody expressed in CHO targeting SLAMF6/CD352. Anti-SLAMF6 Antibody (h20F3ec) has a muIgG1 type heavy chain and a huκ type light chain, with a predicted molecular weight (MW) of 145.9 kDa. The isotype control for Anti-SLAMF6 Antibody (h20F3ec) can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).
Hydroxysafflor yellow A (Safflomin A) is a natural product of flavonoids isolated from safflower. Hydroxysafflor yellow A can inhibit cell proliferation and promote apoptosis through the autophagy pathway. Hydroxysafflor yellow A has anti-inflammatory, antioxidant and antitumor effects. Hydroxysafflor yellow A can be used in the study of cardiovascular disease .
Hydroxysafflor yellow A (Standard) is the analytical standard of Hydroxysafflor yellow A. This product is intended for research and analytical applications. Hydroxysafflor yellow A (Safflomin A) is a natural product of flavonoids isolated from safflower. Hydroxysafflor yellow A can inhibit cell proliferation and promote apoptosis through the autophagy pathway. Hydroxysafflor yellow A has anti-inflammatory, antioxidant and antitumor effects. Hydroxysafflor yellow A can be used in the study of cardiovascular disease .
The MMP-13 protein plays a role in the degradation of extracellular matrix proteins, especially fibrillar collagen, fibronectin, TNC, and ACAN. It cleaves triple-helical collagen, preferentially cleaves type II collagen, and can also target other collagen types. MMP-13 Protein, Human (HEK293) is the recombinant human-derived MMP-13 protein, expressed by HEK293 , with tag free.
The SPEB protein plays a central role in cellular processes as it catalyzes the formation of putrescine from agmatine. This enzyme activity is essential for the biosynthesis of putrescine, a polyamine with important functions in cell growth, proliferation, and various physiological processes. SPEB Protein, E.coli (His-SUMO) is the recombinant E. coli-derived SPEB protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
Thyroid Peroxidase (TPO) orchestrates iodination and coupling within thyroglobulin, leading to the synthesis of thyroid hormones T(3) and T(4).TPO/Thyroid Peroxidase Protein, Mouse (HEK293, His) is the recombinant mouse-derived TPO/Thyroid Peroxidase protein, expressed by HEK293 , with C-His labeled tag.
The MIF protein is a pro-inflammatory cytokine that is critical for the innate immune response against bacterial pathogens. Its presence at sites of inflammation suggests a role in modulating macrophage function to promote host defense. MIF Protein, Human (HEK293, His) is the recombinant human-derived MIF protein, expressed by HEK293 , with C-His labeled tag.
AXL Protein, a receptor tyrosine kinase, mediates signals by binding GAS6, regulating cell survival, proliferation, migration, and differentiation. Upon ligand binding, AXL undergoes dimerization and autophosphorylation, activating downstream molecules like PI3-kinase subunits, GRB2, PLCG1, and more. This triggers AKT kinase activation, influencing processes such as endothelial cell survival, cytokine signaling in NK cell development, hepatic regeneration, gonadotropin-releasing hormone neuron function, platelet activation, thrombotic responses, and immune modulation. AXL also serves as a receptor for lassa virus and lymphocytic choriomeningitis virus during microbial infection. AXL Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived AXL protein, expressed by HEK293 , with C-His labeled tag.
AXL protein is a receptor tyrosine kinase that mediates signals by binding to GAS6 and regulates cell survival, proliferation, migration and differentiation. After ligand binding, AXL dimerizes and autophosphorylates, activating downstream molecules, such as PI3 kinase subunits, GRB2, PLCG1, etc. AXL Protein, Human (HEK293, Fc) is the recombinant human-derived AXL protein, expressed by HEK293 , with C-hFc labeled tag.
GhrA is an enzyme involved in cellular metabolism and plays a crucial role in catalyzing the NADPH-dependent reduction of glyoxylate to glycolate and hydroxypyruvate to glycerate. This enzymatic activity contributes to the conversion of important metabolites and contributes to metabolic pathways related to glyoxylate detoxification and maintenance of cellular homeostasis. GhrA Protein, E.coli (His-SUMO) is the recombinant E. coli-derived GhrA protein, expressed by E. coli , with N-His, N-SUMO labeled tag.
GLXR is a multifunctional enzyme with hydroxypyruvate reductase, glyoxylate reductase, and D-glycerate dehydrogenase activities. It promotes the conversion of hydroxypyruvic acid into D-glyceric acid, glyoxylic acid into glycolic acid, and oxidation of D-glyceric acid into hydroxypyruvic acid. GLXR Protein, Mouse (His-SUMO) is the recombinant mouse-derived GLXR protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
CSAD proteins play a crucial role in the metabolism of sulfur-containing amino acids, catalyzing L-aspartate, 3-sulfinyl-L-alanine (cysteine sulfenic acid) and L-cysteine The acid is decarboxylated to produce β-alanine, hypotaurine and taurine respectively. Among these substrates, 3-sulfinyl-L-alanine is the preferred substrate for CSAD. CSAD Protein, Mouse (His-SUMO) is the recombinant mouse-derived CSAD protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
Trypsin is a digestive endopeptidase that catalyzes the hydrolysis of peptide bonds on the carboxyl side of lysine or arginine residues. Trypsin is synthesized in the acinar cells of the pancreas. Trypsin is converted to the active enzyme in the gut. Trypsin Protein, Pig (P.pastoris, His) is the recombinant pig-derived Trypsin protein, expressed by P. pastoris , with N-6*His labeled tag.
AXL protein is a receptor tyrosine kinase that mediates signals by binding to GAS6 and regulates cell survival, proliferation, migration and differentiation. After ligand binding, AXL dimerizes and autophosphorylates, activating downstream molecules, such as PI3 kinase subunits, GRB2, PLCG1, etc. AXL Protein, Human (Biotinylated, HEK293, Fc) is the recombinant human-derived AXL protein, expressed by HEK293 , with C-hFc labeled tag.
AXL protein is a receptor tyrosine kinase that mediates signals by binding to GAS6 and regulates cell survival, proliferation, migration and differentiation. After ligand binding, AXL dimerizes and autophosphorylates, activating downstream molecules, such as PI3 kinase subunits, GRB2, PLCG1, etc. AXL Protein, Human (HEK293, His-Avi) is the recombinant human-derived AXL protein, expressed by HEK293 , with C-Avi, C-His labeled tag.
AXL protein is a receptor tyrosine kinase that mediates signals by binding to GAS6 and regulates cell survival, proliferation, migration and differentiation. After ligand binding, AXL dimerizes and autophosphorylates, activating downstream molecules, such as PI3 kinase subunits, GRB2, PLCG1, etc. AXL Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived AXL protein, expressed by HEK293 , with C-Avi, C-His labeled tag.
The EGFR protein is a receptor tyrosine kinase that can bind to a variety of ligands, such as EGF, TGFA, AREG, epigen, BTC, epiregulin, and HBEGF, to initiate signaling cascades that mediate cellular responses. This involves receptor dimerization, autophosphorylation and recruitment of adapter proteins such as GRB2, activating downstream pathways such as RAS-RAF-MEK-ERK, PI3-kinase-AKT, PLCgamma-PKC and STAT. EGFR Protein, Human (HEK293, His-Avi) is the recombinant human-derived EGFR protein, expressed by HEK293 , with C-Avi, C-His labeled tag.
Anionic trypsin (serine protease 2, PRSS2) is a member of trypsin family of serine proteases which is found at high levels in pancreatic juice and its upregulation is a characteristic feature of pancreatitis. PRSS2 has also been found to activate pro-urokinase in ovarian tumors, suggesting a function in tumor invasion. PRSS2 potentially participating in the degradation of type II collagen-rich cartilage matrix. Anionic trypsin protein, Dog (His-SUMO) is the recombinant dog-derived Anionic trypsin protein, expressed by E. coli , with N-His, N-SUMO labeled tag.
Cationic trypsin Protein, Dog (His-SUMO) is the recombinant dog-derived Cationic trypsin protein, expressed by E. coli , with N-His, N-SUMO labeled tag.
Cathepsin K protein is a thiol protease that is critical in osteoclastic bone resorption and exhibits potent endoprotease activity against fibrinogen under acidic conditions. Its potential role in extracellular matrix degradation is noteworthy. Cathepsin K Protein, Mouse (His) is the recombinant mouse-derived Cathepsin K protein, expressed by E. coli , with N-6*His labeled tag.
Cathepsin K protein is a thiol protease that is essential for osteoclastic bone resorption and regulation of bone remodeling. It exhibits potent endoprotease activity against fibrinogen under acidic conditions, suggesting its role in extracellular matrix degradation. Cathepsin K Protein, Rat (His) is the recombinant rat-derived Cathepsin K protein, expressed by E. coli , with N-6*His labeled tag.
QPCT Protein synthesizes pyroglutamyl peptides, favoring N-terminal glutaminyl residue over adjacent acidic and tryptophan residues. It catalyzes N-terminal pyroglutamate formation, particularly [Glu-3]-amyloid-beta in APP peptides. In lab settings, it aids pyroglutamate formation in truncated amyloid-beta peptides. QPCT Protein may contribute to N-terminal pyroglutamate formation in peptides linked to amyloid-related plaque development. QPCT Protein, Human (sf9, His) is the recombinant human-derived QPCT protein, expressed by Sf9 insect cells , with N-His labeled tag.
The nicotinamide N-methyltransferase (NNMT) protein catalyzes the methylation of nicotinamide using S-adenosyl-L-methionine to form N1-methylnicotinamide. NNMT affects pluripotent embryonic stem cell development and acts as a metabolic regulator, affecting adipose tissue energy expenditure, gluconeogenesis, and cholesterol biosynthesis. NNMT Protein, Human (GST) is the recombinant human-derived NNMT protein, expressed by E. coli , with N-GST labeled tag.
The EGFR protein is a receptor tyrosine kinase that can bind to a variety of ligands, such as EGF, TGFA, AREG, epigen, BTC, epiregulin, and HBEGF, to initiate signaling cascades that mediate cellular responses. This involves receptor dimerization, autophosphorylation and recruitment of adapter proteins such as GRB2, activating downstream pathways such as RAS-RAF-MEK-ERK, PI3-kinase-AKT, PLCgamma-PKC and STAT. EGFR Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived EGFR protein, expressed by HEK293 , with C-Avi, C-His labeled tag.
The EGFR protein is a receptor tyrosine kinase that can bind to a variety of ligands, such as EGF, TGFA, AREG, epigen, BTC, epiregulin, and HBEGF, to initiate signaling cascades that mediate cellular responses. This involves receptor dimerization, autophosphorylation and recruitment of adapter proteins such as GRB2, activating downstream pathways such as RAS-RAF-MEK-ERK, PI3-kinase-AKT, PLCgamma-PKC and STAT. EGFR vIII Protein, Human (HEK293, His-Avi) is the recombinant human-derived EGFR vIII protein, expressed by HEK293 , with N-Avi, N-His labeled tag.
The EGFR protein is a receptor tyrosine kinase that can bind to a variety of ligands, such as EGF, TGFA, AREG, epigen, BTC, epiregulin, and HBEGF, to initiate signaling cascades that mediate cellular responses. This involves receptor dimerization, autophosphorylation and recruitment of adapter proteins such as GRB2, activating downstream pathways such as RAS-RAF-MEK-ERK, PI3-kinase-AKT, PLCgamma-PKC and STAT. EGFR Protein, Human (FITC, HEK293, His-Avi) is the recombinant human-derived EGFR protein, expressed by HEK293 , with C-Avi, C-His labeled tag.
Cytosine deaminase (CodA) protein plays a key role in the pyrimidine salvage pathway by catalyzing the hydrolytic deamination of cytosine to uracil. This enzyme activity enables cells to efficiently utilize cytosine for pyrimidine nucleotide synthesis. Cytosine deaminase/CodA Protein, E.coli (His-SUMO) is the recombinant E. coli-derived Cytosine deaminase/CodA protein, expressed by E. coli , with N-His, N-SUMO labeled tag.
The EGFRvIII protein is a transmembrane glycoprotein in the protein kinase superfamily that acts as a receptor for epidermal growth factor. It acts on the cell surface, binds to epidermal growth factor, triggers receptor dimerization and tyrosine autophosphorylation, and promotes cell proliferation. EGFR vIII Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived EGFR vIII protein, expressed by HEK293 , with C-Avi, C-His labeled tag.
The EGFR protein is a receptor tyrosine kinase that can bind to a variety of ligands, such as EGF, TGFA, AREG, epigen, BTC, epiregulin, and HBEGF, to initiate signaling cascades that mediate cellular responses. This involves receptor dimerization, autophosphorylation and recruitment of adapter proteins such as GRB2, activating downstream pathways such as RAS-RAF-MEK-ERK, PI3-kinase-AKT, PLCgamma-PKC and STAT. EGFR vIII Protein, Human (FITC, HEK293, His-Avi) is the recombinant human-derived EGFR vIII protein, expressed by HEK293 , with C-Avi, C-His labeled tag.
Acetylcholinesterase (ACHE) protein is pivotal in neurotransmission, rapidly hydrolyzing acetylcholine in the synaptic cleft to terminate signal transduction at the neuromuscular junction. Beyond neurotransmitter regulation, ACHE is implicated in neuronal apoptosis, indicating a broader role in cellular processes associated with programmed cell death. Acetylcholinesterase/ACHE Protein, Human (CHO, His) is the recombinant human-derived Acetylcholinesterase/ACHE protein, expressed by CHO , with C-6*His labeled tag.
IDUA Protein, with catalytic activity, hydrolyzes unsulfated alpha-L-iduronosidic linkages in dermatan sulfate. Its enzymatic function is crucial in breaking down these specific bonds, contributing to the degradation of dermatan sulfate and maintaining cellular homeostasis. IDUA Protein, Human (His) is the recombinant human-derived IDUA protein, expressed by E. coli , with N-6*His labeled tag.
The EGFR protein is a receptor tyrosine kinase that can bind to a variety of ligands, such as EGF, TGFA, AREG, epigen, BTC, epiregulin, and HBEGF, to initiate signaling cascades that mediate cellular responses. This involves receptor dimerization, autophosphorylation and recruitment of adapter proteins such as GRB2, activating downstream pathways such as RAS-RAF-MEK-ERK, PI3-kinase-AKT, PLCgamma-PKC and STAT. PE-Labeled EGFR vIII Protein, Human (HEK293, His-Avi) is the recombinant human-derived EGFR vIII protein, expressed by HEK293 , with C-Avi, C-His labeled tag.
The EphB3 protein is a receptor tyrosine kinase that performs bidirectional signaling with the transmembrane ephrin B ligand. It participates in forward signaling and reverse signaling, sharing functionality with EPHB2. EphB3 Protein, Human (HEK293, His) is the recombinant human-derived EphB3 protein, expressed by HEK293 , with C-His labeled tag.
Complement Factor D/Adipsin Protein cleaves factor B in complex with factor C3b, activating the C3bbb complex to form the C3 convertase in the alternate pathway, analogous to C1s in the classical pathway. Complement Factor D/Adipsin Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived Complement Factor D/Adipsin protein, expressed by HEK293 , with C-hFc labeled tag.
The EphB3 protein is a receptor tyrosine kinase that binds to the transmembrane ephrin B ligand to initiate bidirectional signaling. The forward signal originates from the receptor, while the reverse signal originates from the ephrin ligand. EphB3 Protein, Mouse (HEK293, His) is the recombinant mouse-derived EphB3 protein, expressed by HEK293 , with C-His labeled tag.
Complement factor D, also known as Adipsin, plays a crucial role in the alternative pathway of the complement system and when complexed with factor C3b, it cleaves factor B. This cleavage activates the C3bbb complex, converting it to the C3 convertase of the alternative pathway. Complement Factor D/Adipsin Protein, Human (HEK293, Fc) is the recombinant human-derived Complement Factor D/Adipsin protein, expressed by HEK293 , with C-hFc labeled tag.
Complement Factor D/Adipsin Protein is a member of the S1, or chymotrypsin, family of serine peptidases. Complement Factor D is expressed by adipose cells, plays an important role in both physiology and pathophysiology, where it plays a regulatory role in the complement system. Complement Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Complement Factor D/Adipsin Protein, Rhesus macaque (HEK293, His) is the recombinant Rhesus Macaque-derived Complement Factor D/Adipsin protein, expressed by HEK293 , with C-His labeled tag.
Exopolyphosphatase/PPX protein, a key enzyme, degrades inorganic polyphosphates (polyP) by catalyzing the processive release of orthophosphate. This activity is crucial for regulating cellular polyP levels and is implicated in various biological processes. The protein's role in polyP degradation contributes to maintaining phosphate homeostasis and is integral to the intricate network of cellular processes involving polyP. Exopolyphosphatase/PPX Protein, E.coli (His) is the recombinant E. coli-derived Exopolyphosphatase/PPX protein, expressed by E. coli , with N-6*His labeled tag.
The angiopoietin-4 protein has specific bactericidal activity against Enterococcus faecalis and Listeria monocytogenes, distinct from its lack of efficacy against Lactobacillus innocua and Escherichia coli. Furthermore, Angiogenin-4 exerts pro-angiogenic effects in vitro, suggesting its involvement in supporting the formation of new blood vessels. Angiogenin-4 Protein, Mouse (P.pastoris) is the recombinant mouse-derived Angiogenin-4 protein, expressed by P. pastoris , with N-6*His, N-SUMO labeled tag.
The KYAT1 protein catalyzes the irreversible ammonia action of L-kynurenine to produce kynurenic acid (KA), which is an intermediate in the tryptophan catabolic pathway and a broad-spectrum antagonist of excitatory amino acid receptors. KYAT1 Protein, Human (His) is the recombinant human-derived KYAT1 protein, expressed by E. coli , with C-6*His labeled tag.
Exfoliative toxin A protein, with serine protease-like properties, binds to skin protein profilaggrin, demonstrating cleavage activity after acidic residues. Its involvement is associated with impetigous diseases, particularly staphylococcal scalded skin syndrome (SSSS). Exfoliative toxin A Protein, S. aureus (His) is the recombinant Staphylococcus aureus-derived Exfoliative toxin A protein, expressed by E. coli , with N-6*His labeled tag.
TMK proteins play a central role by catalyzing the phosphorylation of deoxythymidine monophosphate (dTMP), a key step in the synthesis of deoxythymidine triphosphate (dTTP). This process converts dTMP into deoxythymidine diphosphate (dTDP), an important intermediate in dTTP biosynthesis. TMK Protein, Bacillus anthracis (His) is the recombinant TMK protein, expressed by E. coli , with N-6*His labeled tag.
FXN protein activates persulfide transfer in the ISC assembly complex, promoting sulfur transfer and leading to persulfide and sulfide release. It binds ferrous ions, initiates [2Fe-2S] cluster synthesis, and transfers it to chaperone proteins. FXN Protein, Rat is the recombinant rat-derived FXN protein, expressed by E. coli , with tag free.
KYNU, a multifaceted enzyme, plays a pivotal role in the catabolism of tryptophan by catalyzing the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively. Demonstrating a preference for the L-3-hydroxy form, KYNU exhibits cysteine-conjugate-beta-lyase activity, showcasing its versatility in various metabolic pathways. KYNU/Kynureninase Protein, Human (sf9, His) is the recombinant human-derived KYNU/Kynureninase protein, expressed by Sf9 insect cells , with C-His labeled tag.
Propionate kinase, also known as TdcD protein, plays a key role in cellular metabolism by catalyzing the conversion of propionyl phosphate and ADP into propionate and ATP. This enzymatic process is an integral part of the metabolic pathways associated with propionate utilization, facilitating the conversion of propionyl phosphate into propionate, a compound essential for various cellular functions. Propionate kinase/TdcD Protein, E.coli (Myc, His) is the recombinant E. coli-derived Propionate kinase/TdcD protein, expressed by E. coli , with N-His, C-Myc labeled tag.
Trigger protein is essential for protein export, acting as chaperone and peptidyl prolyl cis-trans isomerase. In its chaperone role, it keeps nascent polypeptides in an open conformation, facilitating correct protein folding. Trigger factor Protein, E.coli (P.pastoris, His) is the recombinant E. coli-derived Trigger factor protein, expressed by P. pastoris , with N-His labeled tag.
BLM is an ATP-dependent DNA helicase that can unwind single- and double-stranded DNA in the 3'-5' direction and actively participates in the DNA replication and repair process. Notably, BLM plays a critical role in 5' end resection during double-strand break repair, recruiting DNA2 to cleave 5'-ssDNA. BLM Protein, Mouse (His-Myc) is the recombinant mouse-derived BLM protein, expressed by E. coli , with N-10*His, C-Myc labeled tag.
Catechol-O-methyltransferase (COMT) plays a crucial role by catalyzing and inactivating the O-methylation of catecholamine neurotransmitters and catechol hormones. This enzyme activity is critical for regulating the biological half-life of key neuroactive compounds, including catecholamines. COMT Protein, Human (His) is the recombinant human-derived COMT protein, expressed by E. coli , with N-6*His labeled tag.
FXN protein is a key activator in the core iron-sulfur cluster (ISC) assembly complex, accelerating persulfide transfer to ISCU and [2Fe-2S] cluster assembly. It promotes sulfur transfer, leading to oversulfidation and sulfide release. FXN Protein, Mouse (His) is the recombinant mouse-derived FXN protein, expressed by E. coli , with N-6*His labeled tag.
The thymidine kinase 1/TK1 protein acts as a cell surface receptor in the FCGRT protein. This receptor promotes the transfer of passive humoral immunity from mother to newborn by selectively binding to monomeric immunoglobulin gamma in milk. Thymidine kinase 1/TK1 Protein, Canine (His) is the recombinant canine-derived Thymidine kinase 1/TK1 protein, expressed by E. coli , with C-His labeled tag.
TalB protein, or transaldolase, is pivotal in balancing metabolites in the pentose-phosphate pathway. This enzymatic role is crucial for cellular metabolism, facilitating the interconversion of key sugar phosphates and maintaining metabolite equilibrium. TalB's activity is integral to diverse cellular processes, highlighting its role in supporting dynamic metabolic pathway interplay and cellular homeostasis. TalB Protein, E.coli (Myc, His) is the recombinant E. coli-derived TalB protein, expressed by E. coli , with N-His, C-Myc labeled tag.
The Rnls protein catalyzes the oxidation of the less abundant 1,2-dihydro-β-NAD(P) and 1,6-dihydro-β-NAD(P) to form β-NAD(P)(+). Mainly secreted by the kidneys, this enzyme circulates in the blood and plays a vital role in regulating heart function and systemic blood pressure. Rnls Protein, Mouse (His-SUMO) is the recombinant mouse-derived Rnls protein, expressed by E. coli , with N-His, N-SUMO labeled tag.
Pancreatic lipase (PNLIP) plays a crucial role in fat metabolism by enzymatically breaking down dietary lipids and preferentially selecting long-chain fatty acid esters at positions 1 and 3. This results in the production of mainly 2-monoacylglycerol and free fatty acids. PNLIP/Pancreatic lipase Protein, Mouse (His-SUMO) is the recombinant mouse-derived PNLIP/Pancreatic lipase protein, expressed by E. coli , with N-His, N-SUMO labeled tag.
SPEA is a key enzyme in cellular metabolism responsible for the biosynthesis of agmatine from arginine. This catalytic process involves the conversion of arginine to agmatine, thereby forming a complex network of biochemical pathways within the cell. SPEA Protein, E.coli (His) is the recombinant E. coli-derived SPEA protein, expressed by E. coli , with N-His labeled tag.
The QPCT protein plays a key role in pyroglutamyl peptide biosynthesis and exhibits substrate preference for N-terminal glutamine residues while showing specificity for residues near the N-terminus. Notably, its catalytic activity is independent of chain length beyond the second residue, emphasizing the importance of QPCT in the precise biosynthesis of pyroglutamyl peptides with diverse N-termini, contributing to various biological background. QPCT Protein, Mouse (His) is the recombinant mouse-derived QPCT protein, expressed by E. coli , with N-6*His tag.
BACE1 protein is crucial in proteolytic processing of amyloid precursor protein (APP), initiating cleavage at the N-terminus of the A-beta peptide sequence.This process results in the extracellular release of beta-cleaved soluble APP and a cell-associated C-terminal fragment.BACE1's cleavage activity extends to CHL1, demonstrating its versatility in substrate processing.BACE1 Protein, Human (HEK293, Fc) is the recombinant human-derived BACE1 protein, expressed by HEK293 , with C-hFc labeled tag.
MDP1 Protein, a magnesium-dependent phosphatase, potentially functions as a tyrosine phosphatase. MDP1 Protein, Human (HEK293, His) is the recombinant human-derived MDP1 protein, expressed by HEK293 , with C-6*His labeled tag.
SVMP protein, while lacking significant hemorrhagic activity, functions by inactivating serpins through limited proteolysis of their reactive-site loops. SVMP Protein, Crotalus adamanteus (His) is the recombinant SVMP protein, expressed by E. coli , with N-6*His labeled tag.
Exopolyphosphatase/PPX proteins are dedicated to inorganic polyphosphate (polyP) degradation, expertly releasing orthophosphate from polyphosphate termini in a sustained manner. It shows a strong preference for long-chain polyphosphates, with moderate affinity for shorter sizes (approximately 15 residues). Exopolyphosphatase/PPX Protein, E.coli (His-SUMO) is the recombinant E. coli-derived Exopolyphosphatase/PPX protein, expressed by E. coli , with N-His, N-SUMO labeled tag.
The GFER protein is a FAD-dependent sulfhydryl oxidase that restores redox-active disulfide bonds in CHCHD4/MIA40, an important partner for protein folding in the mitochondrial intermembrane space.GFER Protein, Rat (His-SUMO) is the recombinant rat-derived GFER protein, expressed by E.coli , with N-His, N-SUMO labeled tag.
Beta-ketoacyl-ACP reductase Protein, E.coli (His, Myc) is the recombinant E.coli-derived Beta-ketoacyl-ACP reductase, expressed by E. coli , with N-10*His, C-Myc labeled tag.
Staphopain B is a cysteine protease that severely disrupts host immunity by degrading elastin, fibrin, fibronectin, and kininogen. It blocks phagocytosis of opsonized Staphylococcus aureus and induces neutrophil and monocyte death through proteolytic activity. Staphopain B Protein, S. aureus (GST) is the recombinant Staphylococcus aureus-derived Staphopain B protein, expressed by E. coli , with N-GST labeled tag.
The QPCT protein plays a key role in pyroglutamyl peptide biosynthesis and exhibits substrate preference for N-terminal glutamine residues while showing specificity for residues near the N-terminus. Notably, its catalytic activity is independent of chain length beyond the second residue, emphasizing the importance of QPCT in the precise biosynthesis of pyroglutamyl peptides with diverse N-termini, contributing to various biological background. QPCT Protein, Mouse (HEK293, His) is the recombinant mouse-derived QPCT protein, expressed by HEK293 , with N-His, N-Myc labeled tag.
GSTP1, a key protein, aids in cellular detoxification by conjugating reduced glutathione to hydrophobic electrophiles. It also forms glutathione conjugates for PGA2 and PGJ2 and contributes to hepoxilin synthesis. Additionally, GSTP1 regulates CDK5 activity, preventing neurodegeneration. This versatile enzyme safeguards cellular homeostasis and plays a crucial role in various biochemical pathways. GSTP1 Protein, Cricetulus longicaudatus (His-Myc) is the recombinant GSTP1 protein, expressed by E. coli , with N-10*His, C-Myc labeled tag.
EphA2 protein is a receptor tyrosine kinase that participates in bidirectional signaling with ephrin A ligands, affecting migration, adhesion, proliferation and differentiation. EphA2 interacts with DSG1, inhibits ERK1/ERK2 signaling, and affects cell adhesion and UV radiation-induced apoptosis. EphA2 Protein, Cynomolgus (HEK293, hFc) is the recombinant cynomolgus-derived EphA2 protein, expressed by HEK293 , with C-hFc labeled tag.
The DDR1 protein is a fibrillar collagen receptor that coordinates key cellular processes including matrix remodeling, migration, differentiation, survival, and proliferation. Upon collagen binding, DDR1 activates signaling cascades involving SRC and MAP kinases, promoting matrix remodeling through MMP upregulation, promoting cell migration, wound healing, and tumor invasion. DDR1 Protein, Mouse (HEK293, C-His) is the recombinant mouse-derived DDR1, expressed by HEK293 , with C-6*His labeled tag.
AMCase/CHIA Protein, an enzyme, is a member of the chitinase family that hydrolyzes chitin, a component of the fungal cell wall. It plays a crucial role in the immune response against fungal infections. AMCase/CHIA Protein's potential as a therapeutic target lies in its ability to modulate the immune system and its involvement in allergic diseases and asthma. AMCase/CHIA Protein, Mouse (HEK293, His) is the recombinant mouse-derived AMCase/CHIA protein, expressed by HEK293 , with C-His labeled tag.
AMCase/CHIA protein is an enzyme that degrades chitin and chitotriose and is involved in defense against nematodes, fungi, and pathogens.It plays a role in Th2 immune responses, in response to IL-13, and in the induction of inflammation.AMCase/CHIA Protein, Human (HEK293, His) is the recombinant human-derived AMCase/CHIA protein, expressed by HEK293 , with C-His labeled tag.
EphA2 protein is a receptor tyrosine kinase that participates in bidirectional signaling with ephrin A ligands, affecting migration, adhesion, proliferation and differentiation. EphA2 interacts with DSG1, inhibits ERK1/ERK2 signaling, and affects cell adhesion and UV radiation-induced apoptosis. EphA2 Protein, Cynomolgus (HEK293, His-Avi) is the recombinant cynomolgus-derived EphA2 protein, expressed by HEK293 , with C-Avi, C-His labeled tag.
RuvA protein is a core component of the RuvA-RuvB-RuvC complex and plays a key role in gene recombination and DNA repair, especially in the processing of Holliday junction (HJ) DNA. RuvA cooperates with RuvB to promote HJ branch migration, binds to HJ cruciform DNA and imparts an open structure. RuvA Protein, E.coli (His-SUMO) is the recombinant E. coli-derived RuvA protein, expressed by E. coli , with N-SUMO, N-6*His labeled tag.
RuvB protein is an important component of the RuvABC complex and plays a key role in recombinant DNA repair, especially for UV-induced damage. It helps rescue stalled DNA replication forks through replication fork reversal (RFR). RuvB Protein, E.coli (His-SUMO) is the recombinant E. coli-derived RuvB protein, expressed by E. coli , with N-SUMO, N-6*His labeled tag.
Plasma kallikrein/KLKB1 enzymatically cleaves Lys-Arg and Arg-Ser bonds, triggering factor XII activation upon binding to a negatively charged surface.It liberates bradykinin from HMW kininogen and is implicated in the renin-angiotensin system, potentially converting prorenin into renin.This highlights the protein's multifaceted role in various physiological processes.Plasma kallikrein/KLKB1 Protein, Rat (P.pastoris, His) is the recombinant rat-derived Plasma kallikrein/KLKB1 protein, expressed by P.pastoris , with N-6*His labeled tag.
Hemagglutinin esterase is a structural protein with a short spike that is critical for viral attachment and initiation of infection. It exhibits receptor binding and destructive activities, de-O-acetylating possible viral receptor determinants. HE/Hemagglutinin-esterase Protein, Bovine (P.pastoris, His) is the recombinant bovine-derived HE/Hemagglutinin-esterase, expressed by P. pastoris , with N-His labeled tag.
GSTP1, a key protein, aids in cellular detoxification by conjugating reduced glutathione to hydrophobic electrophiles. It also forms glutathione conjugates for PGA2 and PGJ2 and contributes to hepoxilin synthesis. Additionally, GSTP1 regulates CDK5 activity, preventing neurodegeneration. This versatile enzyme safeguards cellular homeostasis and plays a crucial role in various biochemical pathways. GSTP1 Protein, Cricetulus longicaudatus (sf9, His-Myc) is the recombinant GSTP1 protein, expressed by Sf9 insect cells , with N-10*His, C-Myc labeled tag.
CES3/CES1D Protein, a major lipase in white adipose tissue, plays a crucial role in xenobiotic and natural substrate metabolism. It hydrolyzes triacylglycerols and monoacylglycerols, showing a preference for the latter, with susceptibility increasing as the acyl chain length decreases. Additionally, CES3/CES1D catalyzes the synthesis of fatty acid ethyl esters and hydrolyzes retinyl esters. CES3/CES1D Protein, Mouse (HEK293, His) is the recombinant mouse-derived CES3/CES1D protein, expressed by HEK293 , with C-6*His labeled tag.
Enterokinase Protein initiates the activation of pancreatic proteolytic proenzymes, including trypsin, chymotrypsin, and carboxypeptidase A. It catalyzes the conversion of trypsinogen to trypsin, triggering the activation of other proenzymes like chymotrypsinogen, procarboxypeptidases, and proelastases. Enterokinase Protein, Human (HEK293, His) is the recombinant human-derived Enterokinase protein, expressed by HEK293 , with C-10*His labeled tag.
The PpsA protein plays a crucial role in cellular metabolism by catalyzing the conversion of pyruvate to phosphoenolpyruvate, a key step in glycolysis and gluconeogenesis. This enzyme activity is the basis for the interconversion of metabolic intermediates and contributes to the regulation of intracellular energy production and utilization. PpsA Protein, E.coli (His-SUMO) is the recombinant E. coli-derived PpsA protein, expressed by E. coli , with N-His, N-SUMO labeled tag.
The FkpA protein plays a central role in cellular processes, acting as a key catalyst in the complex dance of protein folding. Its catalytic efficiency is excellent in promoting the cis-trans isomerization of proline-imine peptide bonds, thus accelerating the overall folding of proteins. FkpA Protein, E.coli (His-SUMO) ) is the recombinant E. coli-derived FkpA protein, expressed by E. coli , with N-His, N-SUMO labeled tag.
GLO2, or Glyoxalase II Protein, serves as a thiolesterase, playing a crucial role in catalyzing the hydrolysis of S-D-lactoyl-glutathione. This activity generates glutathione and D-lactic acid, emphasizing GLO2's significance in cellular metabolism. The enzyme contributes to regulating glutathione levels and the conversion of substrates within cellular pathways. GLO2/Glyoxalase II Protein, Human (GST) is the recombinant human-derived GLO2/Glyoxalase II protein, expressed by E. coli , with N-GST labeled tag.
MCT/SACOL1244 Protein intricately participates in lipid metabolism, specifically playing a vital role in fatty acid biosynthesis. MCT/SACOL1244 Protein, S. aureus (P.pastoris, His) is the recombinant Staphylococcus aureus-derived MCT/SACOL1244 protein, expressed by P. pastoris , with N-6*His labeled tag.
Arginase-1 (ARG1) plays a key role in the urea cycle, converting L-arginine into urea and L-ornithine. This cycle maintains L-arginine homeostasis, which is critical for nitric oxide synthase to compete for arginine. Arginase-1/ARG1 Protein, Mouse (P.pastoris, His) is the recombinant mouse-derived Arginase-1/ARG1 protein, expressed by P. pastoris , with N-6*His labeled tag.
AICDA Protein, Mouse (His-Myc) is an enzyme that mediates affinity maturation and facilitates DNA demethylation in germinal center (GC) B cells. AICDA Protein overexpression causes more aggressive disease in BCL2-driven murine lymphomas.
Lipoic acid protein ligase A (LplA) is a key enzyme involved in the activation and transfer of lipoic acid, an important cofactor, to the lipoyl domain of lipoic acid-dependent enzymes. LplA catalyzes the ATP-dependent activation of exogenous lipoic acid, converting it to lipoyl-AMP as an intermediate. Lipoate-protein ligase A/LplA Protein, E.coli (His-SUMO) is the recombinant E. coli-derived Lipoate-protein ligase A/LplA protein, expressed by E. coli , with N-SUMO, N-6*His labeled tag.
PAG-1, a protein of interest, exhibits apparent proteolytic inactivity. PAG-1 Protein, Bovine (His) is the recombinant bovine-derived PAG-1 protein, expressed by E. coli , with N-His labeled tag.
PKM2 protein catalyzes the final step of glycolysis, transferring a phosphoryl group from PEP to ADP to generate ATP.In the nucleus, transcriptional activation of PKM2 contributes to cancer progression, promoting cell proliferation and tumorigenesis.PKM2 is also involved in caspase-independent cell death in tumors.PKM2 Protein, Mouse (Baculovirus, His) is the recombinant mouse-derived PKM2 protein, expressed by Sf9 insect cells , with N-10*His labeled tag.
Frataxin (FXN) protein activates persulfide transfer, which is critical for [2Fe-2S] cluster assembly. It accelerates sulfur transfer from NFS1 persulfide to ISCU and small thiols, resulting in oversulfide and sulfide release. Frataxin/FXN Protein, Cynomolgus (His) is the recombinant cynomolgus-derived Frataxin/FXN protein, expressed by E. coli , with N-6*His labeled tag.
APT, also known as adenine phosphoribosyltransferase, plays a crucial role in the rescue reaction that forms AMP (adenosine monophosphate). This salvage pathway provides a more energy-efficient route for AMP synthesis than de novo synthesis. APT Protein, Streptococcus pyogenes serotype M1 (Sf9, His-Myc) is the recombinant APT protein, expressed by Sf9 insect cells , with N-10*His, C-Myc labeled tag.
GSTP1 protein conjugates reduced glutathione to hydrophobic electrophiles, forms glutathione conjugates of PGA2 and PGJ2, and contributes to hepoxilin production.It also regulates CDK5 activity by facilitating p25/p35 translocation, preventing neurodegeneration.GSTP1 Protein, Rat (His) is the recombinant rat-derived GSTP1 protein, expressed by E.coli , with N-6*His labeled tag.
HPSE proteins cleave HSPG into heparan sulfate side chains and decorin, involved in ECM degradation and remodeling. HPSE promotes cell migration associated with metastasis, wound healing, and inflammation and acts as a procoagulant. HPSE also induces AKT1/PKB phosphorylation, enhancing angiogenesis, hair follicle differentiation and homeostasis. HPSE Protein, Rat (His-Myc) is the recombinant rat-derived HPSE protein, expressed by E. coli , with N-10*His, C-Myc labeled tag.
PGA5 protein, with broad substrate specificity, prefers cleaving phenylalanine and leucine bonds but also shows the ability to cleave various other bonds to some extent. Animal-Free PGA5 Protein, Human (His) is the recombinant human-derived animal-FreePGA5 protein, expressed by E. coli , with C-His labeled tag. This product is for cell culture use only.
MMP-10 protein is a member of the matrix metalloproteinase family and plays a crucial role in extracellular matrix remodeling by promoting the degradation of various substrates. As a protease, MMP-10 is involved in tissue homeostasis, wound healing, and inflammatory responses. MMP-10 Protein, Human (P. pastoris, His) is the recombinant human-derived MMP-10 protein, expressed by P. pastoris , with N-6*His labeled tag.
Hygromycin-B kinase/HPH Proteinas, an aminoglycoside phosphotransferase, phosphorylates and inactivates antibiotic substrates, including hygromycin and related compounds. This selective enzymatic activity highlights its specificity within the aminoglycoside class, regulating antibiotic function and potentially influencing microbial resistance mechanisms. Hygromycin-B kinase/HPH Protein, E.coli (His-SUMO) is the recombinant E. coli-derived Hygromycin-B kinase/HPH protein, expressed by E. coli , with N-His, N-SUMO labeled tag.
The function of the CELA2A protein as elastase goes beyond its traditional role as it not only enhances insulin signaling but also appears to play a potential physiological role in cellular glucose metabolism. This multifaceted protein circulates in the plasma and exerts regulatory effects by reducing platelet overactivation. CELA2A Protein, Human (His) is the recombinant human-derived CELA2A protein, expressed by E. coli , with N-6*His labeled tag.
TPP2 protein, a cytosolic tripeptidyl-peptidase, is a vital component of the ubiquitin-proteasome pathway, operating downstream of the 26S proteasome. It plays a crucial role in maintaining intracellular amino acid homeostasis by releasing N-terminal tripeptides from polypeptides. Furthermore, TPP2 protein is implicated in stimulating adipogenesis, contributing to processes involved in adipose tissue formation. TPP2 Protein, Human (Myc, His) is the recombinant human-derived TPP2 protein, expressed by E. coli , with N-His, C-Myc labeled tag.
RuvC protein is an important component of the RuvA-RuvB-RuvC complex and is essential for the processing of Holliday junctions in gene recombination and DNA repair. As an endonuclease, RuvC resolves Holliday junctions by generating symmetric single-stranded nicks that rely on a central homology core. RuvC Protein, E.coli (His-SUMO) is the recombinant E. coli-derived RuvC protein, expressed by E. coli , with N-SUMO, N-6*His labeled tag.
LUXS proteins are critical for the synthesis of bacterially secreted autoinducer 2 (AI-2), which promotes communication between cell density and environmental metabolism. LUXS is critical for quorum sensing and catalyzes S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentanedione (DPD) , revealing its enzymatic role in AI-2 production. LUXS Protein, E.coli (His) is the recombinant E. coli-derived LUXS protein, expressed by E. coli , with N-6*His labeled tag.
Kallikrein-14 protein is a serine-type endopeptidase with multiple substrate specificities and has trypsin-like and chymotrypsin-like activities. It activates/inactivates protease-activated receptors (F2R, F2RL1, F2RL3) and other kallikreins (KLK1, KLK3, KLK5, KLK11). Kallikrein-14 Protein, Mouse (His) is the recombinant mouse-derived Kallikrein-14 protein, expressed by E. coli , with N-His labeled tag.
Kallikrein-8 is a serine protease that degrades proteins such as casein and fibrinogen. It cleaves L1CAM, inducing neurite outgrowth and fasciculations. Kallikrein-8 Protein, Mouse (P.pastoris, His) is the recombinant mouse-derived Kallikrein-8 protein, expressed by P. pastoris , with N-6*His labeled tag.
Hygromycin-B kinase/HPH Proteinas, an aminoglycoside phosphotransferase, phosphorylates and inactivates antibiotic substrates, including hygromycin and related compounds. This selective enzymatic activity highlights its specificity within the aminoglycoside class, regulating antibiotic function and potentially influencing microbial resistance mechanisms. Hygromycin-B kinase/HPH Protein, E.coli (P. pastoris, His) is the recombinant E. coli-derived Hygromycin-B kinase/HPH protein, expressed by P. pastoris , with N-6*His labeled tag.
The CDK6ic complex is an important serine/threonine protein kinase that regulates cell cycle progression and differentiation, promoting the G1/S transition by phosphorylating substrates such as pRB/RB1 and NPM1. It interacts with D-type G1 cyclins during interphase to form active pRB/RB1 kinase, which controls cell cycle entry. CDK6 Protein, Human (Sf9, His-Avi) is the recombinant human-derived CDK6, expressed by Sf9 insect cells , with N-His, N-Avi labeled tag.
The PPIase A protein plays a central role in complex protein folding, utilizing its peptidyl-prolyl cis-trans isomerase (PPIase) activity to accelerate dynamic conformational changes that are critical for proper protein maturation. PPIase A specifically catalyzes the cis-trans isomerization of proline imide peptide bonds, effectively promoting protein folding. PPIase A Protein, E.coli (His-SUMO) is the recombinant E. coli-derived PPIase A protein, expressed by E. coli , with N-His, N-SUMO labeled tag.
cGB-PDE protein regulates signal transduction by specifically hydrolyzing cto 5'-GMP, thereby controlling the intracellular concentration of cyclic nucleotides, particularly nitric-oxide-generated cGMP. cGB-PDE Protein, Mouse (Myc, His) is the recombinant mouse-derived cGB-PDE protein, expressed by E. coli , with N-His, C-Myc labeled tag.
Hydroxy acid oxidase 1 (HAO1) is a multifunctional (S)-2-hydroxyacid oxidase with a strong preference for glycolate oxidation. This enzymatic process produces glyoxylic acid, an important precursor for the synthesis of glycine by alanine glyoxylate aminotransferase, which prevents glyoxylic acid accumulation and kidney stone formation. Hydroxyacid oxidase 1 Protein, Mouse (His) is the recombinant mouse-derived Hydroxyacid oxidase 1 protein, expressed by E. coli , with N-His labeled tag.
ADAM12 Protein, Mouse (Sf9, His-Myc) is a disintegrin and a metalloprotease. ADAM12 is upregulated in epithelial cancers and contributes to increased tumor proliferation, metastasis, and endocrine resistance.
Arginase-2 (ARG2) is a multifunctional regulator central to the regulation of arginine metabolism and nitric oxide synthesis outside the urea cycle. In addition to its hepatic effects, ARG2 affects innate and adaptive immune responses, negatively affecting the survival of activated CD4(+) and CD8(+) T cells. Arginase-2/ARG2 Protein, Mouse (His-SUMO) is the recombinant mouse-derived Arginase-2/ARG2 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
ASPH protein phosphorylates SPRTN, facilitating its chromatin recruitment and decreasing replication stress. ASPH activates the G2/M checkpoint by phosphorylating and inhibiting PABIR1/FAM122A, leading to serine/threonine-protein phosphatase 2A-mediated dephosphorylation and stabilization of WEE1 levels and activity. ASPH Protein, Human (His-SUMO) is the recombinant human-derived ASPH protein, expressed by E. coli, with N-6*His, N-SUMO labeled tag.
The MIF protein is a pro-inflammatory cytokine that is critical for the innate immune response against bacterial pathogens. Its presence at sites of inflammation suggests a role in modulating macrophage function to promote host defense. MIF Protein, Human (HEK293, hFc) is the recombinant human-derived MIF protein, expressed by HEK293 , with C-hFc labeled tag.
The MIF protein is a pro-inflammatory cytokine that plays a crucial role in the innate immune response against bacterial pathogens.Its presence at sites of inflammation suggests its role as a mediator in the regulation of macrophage function during host defense.MIF Protein, Mouse (P.pastoris, His) is the recombinant mouse-derived MIF protein, expressed by P.pastoris , with N-6*His labeled tag.
The MCR-1 protein may catalyze the addition of a phosphoethanolamine moiety to lipid A, which is associated with polymyxin resistance. This modification observed in E. coli expressing MCR-1 increased the minimum inhibitory concentration (MIC) of colistin and polymyxin B. MCR-1 Protein, E.coli (Cell-Free, His-SUMO) is the recombinant E. coli-derived MCR-1 protein, expressed by E. coli Cell-free , with labeled tag.
The MCR-1 protein may catalyze the addition of a phosphoethanolamine moiety to lipid A, which is associated with polymyxin resistance. This modification observed in E. coli expressing MCR-1 increased the minimum inhibitory concentration (MIC) of colistin and polymyxin B. MCR-1 protein, E.coli (364a.a, His-SUMO) is the recombinant E. coli-derived MCR-1 protein, expressed by E. coli , with N-His, N-SUMO labeled tag.
The TFIIF-related CTD phosphatase protein plays a key role in promoting RNA polymerase II activity by dephosphorylating "Ser-2" and "Ser-5" residues. This enhances the function of RNA polymerase II, allowing the protein to participate in the transcription process. TFIIF-associating CTD phosphatase Protein, Mouse (Myc, His) is the recombinant mouse-derived TFIIF-associating CTD phosphatase protein, expressed by E. coli , with N-His, C-Myc labeled tag.
Anionic trypsin-2 belongs to the trypsin family of serine proteases and encodes anionic trypsinogen.Anionic trypsin-2 is part of a cluster of trypsinogen genes that are located within the T cell receptor beta locus.Anionic trypsin-2 Protein, Rat (P.pastoris, His) is the recombinant rat-derived Anionic trypsin-2 protein, expressed by P.pastoris , with N-His labeled tag.
The NEU2 protein plays a key role in cellular processes by catalyzing the removal of sialic acid (N-acetylneuraminic acid) moieties from glycoproteins, oligosaccharides, and gangliosides. Through its enzymatic activity, NEU2 contributes to the controlled modification of cell surface glycoconjugates, affecting various cellular functions including cell adhesion, signaling, and immune responses. NEU2 Protein, Cricetulus griseus (Sf9, His-Myc) is the recombinant NEU2 protein, expressed by Sf9 insect cells , with N-10*His, C-Myc labeled tag.
DLL1 protein is a transmembrane ligand for NOTCH1, NOTCH2 and NOTCH3 receptors and participates in cis- and trans-interactions. Trans interactions trigger mechanical forces through clathrin-mediated endocytosis, involving ligand ubiquitination, EPN1 interactions, and actin polymerization. Delta-like protein 1/DLL1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Delta-like protein 1/DLL1 protein, expressed by HEK293 , with C-His labeled tag.
Delta-like protein 1 (DLL1) is a transmembrane ligand for NOTCH1, NOTCH2, and NOTCH3 receptors and participates in cis- and trans-interactions with their extracellular domains. Upon interaction, DLL1 induces mechanical forces that promote Notch signaling by triggering NICD nuclear accumulation. Delta-like protein 1/DLL1 Protein, Rat (HEK293, Fc) is the recombinant rat-derived Delta-like protein 1/DLL1 protein, expressed by HEK293 , with C-hFc labeled tag.
Delta-like protein 1 (DLL1) is a transmembrane ligand for NOTCH1, NOTCH2, and NOTCH3 receptors and participates in cis- and trans-interactions with their extracellular domains. Upon interaction, DLL1 induces mechanical forces that promote Notch signaling by triggering NICD nuclear accumulation. Delta-like protein 1/DLL1 Protein, Rat (HEK293, His) is the recombinant rat-derived Delta-like protein 1/DLL1 protein, expressed by HEK293 , with C-His labeled tag.
The Carbonic Anhydrase 9 protein is responsible for catalyzing the interconversion between carbon dioxide and water, as well as facilitating the conversion of carbonic acid into its dissociated ions, namely bicarbonate and hydrogen ions. Carbonic Anhydrase 9 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Carbonic Anhydrase 9 protein, expressed by HEK293 , with C-His labeled tag.
The FGFR-3 protein is a tyrosine-protein kinase receptor for fibroblast growth factor that is critical for cellular processes, particularly in chondrocytes, osteoblasts, and inner ear development. Its effects span normal skeletal development and postnatal bone mineralization. FGFR-3 alpha (IIIb) Protein, Human (HEK293, His-Avi) is the recombinant human-derived FGFR-3 alpha, expressed by HEK293 , with C-Avi, C-His labeled tag.
The FGFR-3 protein is a tyrosine-protein kinase receptor for fibroblast growth factor that is critical for cellular processes, particularly in chondrocytes, osteoblasts, and inner ear development. Its effects span normal skeletal development and postnatal bone mineralization. FGFR-3 beta (IIIb) Protein, Human (HEK293, His-Avi) is the recombinant human-derived FGFR-3 beta, expressed by HEK293 , with C-Avi, C-His labeled tag.
ACPS, an essential enzyme in cellular processes, transfers the 4'-phosphopantetheine moiety from coenzyme A to a serine residue of acyl-carrier-protein. ACPS Protein, Streptococcus pyogenes serotype M28 (His) is the recombinant ACPS protein, expressed by E. coli , with N-6*His labeled tag.
The FGFR-3 protein is a tyrosine-protein kinase receptor for fibroblast growth factor that is critical for cellular processes, particularly in chondrocytes, osteoblasts, and inner ear development. Its effects span normal skeletal development and postnatal bone mineralization. FGFR-3 alpha (IIIc) Protein, Human (HEK293, His-Avi) is the recombinant human-derived FGFR-3 alpha, expressed by HEK293 , with C-Avi, C-His labeled tag.
The FGFR-3 protein is a tyrosine-protein kinase receptor for fibroblast growth factor that is critical for cellular processes, particularly in chondrocytes, osteoblasts, and inner ear development. Its effects span normal skeletal development and postnatal bone mineralization. FGFR-3 beta (IIIc) Protein, Human (HEK293, His-Avi) is the recombinant human-derived FGFR-3 beta, expressed by HEK293 , with C-Avi, C-His labeled tag.
The MIF protein is a pro-inflammatory cytokine that is critical for the innate immune response against bacterial pathogens. Its presence at sites of inflammation suggests a role in modulating macrophage function to promote host defense. MIF Protein, Human (N-His, C-Myc) is the recombinant human-derived MIF protein, expressed by E. coli , with C-Myc, N-10*His labeled tag.
Carbonic Anhydrase 9 Protein catalyzes the reversible hydration of carbon dioxide, essential for converting it to bicarbonate ions and protons, and vice versa. This enzymatic activity is crucial in physiological processes like acid-base balance regulation, respiration, and cellular pH homeostasis. Carbonic Anhydrase 9 Protein is vital for carbon dioxide transport and metabolism, contributing to overall regulation of its levels in the body. Carbonic Anhydrase 9 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived Carbonic Anhydrase 9 protein, expressed by HEK293 , with C-His labeled tag.
Receptor-type tyrosine-protein phosphatase C (PTPRC) is a receptor type PTP and an essential positive regulator of T- and B-cell antigen receptor signaling. PTPRC functions through direct interaction with antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. PTPRC also suppresses JAK kinases as a regulator of cytokine receptor signaling. CD45 Protein, Human (HEK293, His-Avi) is the recombinant human-derived CD45 protein, expressed by HEK293 , with C-Avi, C-His labeled tag.
Protease 7/OmpT protein is a multifunctional enzyme that can cleave a variety of substrates, such as T7 RNA polymerase, ferric enterobactin receptor protein (FEP), and the antimicrobial peptide protamine. Its unique specificity for paired basic residues suggests a preference for specific amino acid configurations. Protease 7/OmpT Protein, E.coli (His) is the recombinant E. coli-derived Protease 7/OmpT protein, expressed by E. coli , with N-6*His labeled tag.
Gamma-GCS protein is a key enzyme in sulfur metabolism and initiates glutathione synthesis by catalyzing the incorporation of L-cysteine and L-glutamic acid. This important molecule critical for cellular antioxidant defense is synthesized through a critical 1/2 step facilitated by γ-GCS. Gamma-GCS Protein, E.coli (His-SUMO) is the recombinant E. coli-derived Gamma-GCS protein, expressed by E. coli , with N-His, N-SUMO labeled tag.
MUSK protein is a receptor tyrosine kinase that plays a critical role in the formation of the neuromuscular junction (NMJ).MUSK is activated by the AGRIN-LRP4 complex and regulates the NMJ through gene expression, actin cytoskeleton reorganization, and acetylcholine receptor (AChR) clustering.MUSK Protein, Mouse (Myc, His-SUMO) is the recombinant mouse-derived MUSK protein, expressed by E.coli , with C-Myc, N-SUMO, N-10*His labeled tag.
Complement Factor D/Adipsin Protein is pivotal, cleaving factor B within the factor C3b complex to activate the C3bbb complex, serving as the C3 convertase in the alternate pathway—analogous to C1s in the classical pathway. Complement Factor D/Adipsin Protein, Rat (P.pastoris, His) is the recombinant rat-derived Complement Factor D/Adipsin protein, expressed by P. pastoris , with N-6*His labeled tag.
Coagulation factor XII (F12) is a serum glycoprotein that plays multiple roles in initiating blood coagulation, fibrinolysis, and the production of bradykinin and angiotensin. It is involved in these complex processes, including cleavage of prekallikrein to form kallikrein, which subsequently cleaves factor XII initially to α-factor XIIa and then, after trypsin cleavage, to β-factor XIIa. Coagulation Factor XII/F12 Protein, Pig (His) is the recombinant pig-derived Coagulation Factor XII/F12 protein, expressed by E. coli , with N-6*His labeled tag.
The FGFR-3 protein is a tyrosine-protein kinase receptor for fibroblast growth factor that is critical for cellular processes, particularly in chondrocytes, osteoblasts, and inner ear development. Its effects span normal skeletal development and postnatal bone mineralization. FGFR-3 alpha (IIIb) Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived FGFR-3 alpha, expressed by HEK293 , with C-Avi, C-His labeled tag.
The FGFR-3 protein is a tyrosine-protein kinase receptor for fibroblast growth factor that is critical for cellular processes, particularly in chondrocytes, osteoblasts, and inner ear development. Its effects span normal skeletal development and postnatal bone mineralization. FGFR-3 beta (IIIb) Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived FGFR-3 beta, expressed by HEK293 , with C-Avi, C-His labeled tag.
Receptor-type tyrosine-protein phosphatase C (PTPRC) is a receptor type PTP and an essential positive regulator of T- and B-cell antigen receptor signaling. PTPRC functions through direct interaction with antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. PTPRC also suppresses JAK kinases as a regulator of cytokine receptor signaling. PTPRC/CD45RABC Protein, Human (HEK293, His) is the recombinant human-derived PTPRC/CD45RABC protein, expressed by HEK293 , with C-His labeled tag.
The FGFR-3 protein is a tyrosine-protein kinase receptor for fibroblast growth factor that is critical for cellular processes, particularly in chondrocytes, osteoblasts, and inner ear development. Its effects span normal skeletal development and postnatal bone mineralization. FGFR-3 alpha (IIIc) Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived FGFR-3 alpha IIIc protein, expressed by HEK293 , with C-Avi, C-His labeled tag.
The FGFR-3 protein is a tyrosine-protein kinase receptor for fibroblast growth factor that is critical for cellular processes, particularly in chondrocytes, osteoblasts, and inner ear development. Its effects span normal skeletal development and postnatal bone mineralization. FGFR-3 beta (IIIc) Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived FGFR-3 beta IIIc protein, expressed by HEK293 , with C-Avi, C-His labeled tag.
Receptor-type tyrosine-protein phosphatase C (PTPRC) is a receptor type PTP and an essential positive regulator of T- and B-cell antigen receptor signaling. PTPRC functions through direct interaction with antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. PTPRC also suppresses JAK kinases as a regulator of cytokine receptor signaling. CD45 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived CD45 protein, expressed by HEK293 , with C-His, C-Avi labeled tag.
The carbonic anhydrase 9 (CA9) protein plays a crucial role as a catalyst in the conversion of carbon dioxide and water. It promotes the formation of bicarbonate and hydrogen ions (dissociated ions of carbonic acid). Carbonic Anhydrase 9 Protein, Human (HEK293, His-Avi) is the recombinant human-derived Carbonic Anhydrase 9 protein, expressed by HEK293 , with C-Avi, C-His labeled tag.
Receptor-type tyrosine-protein phosphatase C (PTPRC) is a receptor type PTP and an essential positive regulator of T- and B-cell antigen receptor signaling. PTPRC functions through direct interaction with antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. PTPRC also suppresses JAK kinases as a regulator of cytokine receptor signaling. PTPRC/CD45RABC Protein, Human (HEK293, hFc) is the recombinant human-derived PTPRC/CD45RABC protein, expressed by HEK293 , with C-hFc labeled tag.
DLL1 protein is a transmembrane ligand for NOTCH1, NOTCH2 and NOTCH3 receptors and participates in cis- and trans-interactions. Trans interactions trigger mechanical forces through clathrin-mediated endocytosis, involving ligand ubiquitination, EPN1 interactions, and actin polymerization. Delta-like protein 1/DLL1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Delta-like protein 1/DLL1 protein, expressed by HEK293 , with C-His labeled tag.
Protease 7, or OmpT, displays unique proteolytic capabilities, cleaving diverse substrates like T7 RNA polymerase, ferric enterobactin receptor protein (FEP), and protamine. With specificity for paired basic residues, it selectively targets substrates with such motifs, highlighting its pivotal role in diverse biological processes and protein regulation. Protease 7/OmpT Protein, E.coli (His-SUMO) is the recombinant E. coli-derived Protease 7/OmpT protein, expressed by E. coli , with N-His, N-SUMO labeled tag.
The OGDC-E Protein, a vital component of the 2-oxoglutarate dehydrogenase complex, drives the conversion of 2-oxoglutarate to succinyl-CoA in the mitochondrion, a pivotal step in the Krebs cycle.It employs thiamine diphosphate for decarboxylation, connecting to the E2 enzyme and participating in nuclear histone succinylation with KAT2A.OGDC-E Protein, Mouse (His-SUMO) is the recombinant mouse-derived OGDC-E protein, expressed by E.coli , with N-SUMO, N-6*His labeled tag.
The transmembrane protease serine 4 (TMPRSS4) protein is a plasma membrane-anchored serine protease that is critical for activating molecular pathways. Its proteolytic activity directly processes pro-uPA/PLAU into its active form. Transmembrane protease serine 4 Protein, Mouse (His-SUMO) is the recombinant mouse-derived Transmembrane protease serine 4 protein, expressed by E. coli , with N-His, N-SUMO labeled tag.
CELA2A Protein, a serine protease, is involved in the digestion of dietary proteins in the small intestine. It cleaves peptide bonds, breaking down proteins into smaller peptides and amino acids for absorption. CELA2A Protein, Mouse (His) is the recombinant mouse-derived CELA2A protein, expressed by E. coli , with N-6*His labeled tag.
The HAS2 protein adds GlcNAc or GlcUA monosaccharides to hyaluronic acid, playing a crucial role in its synthesis. HAS2 Protein, Mouse (His) is the recombinant mouse-derived HAS2 protein, expressed by E. coli , with N-6*His labeled tag.
PDK4 protein is a key kinase that regulates glucose and fatty acid metabolism by phosphorylating pyruvate dehydrogenase subunits PDHA1 and PDHA2.This inhibits pyruvate dehydrogenase activity, modulates metabolite flux and inhibits aerobic respiration.PDK4 Protein, Mouse (221a.a, His )is the recombinant mouse-derived PDK4 protein, expressed by E. coli
, with N-6*His tag.
Beta-lactamase CTX-M-1/Bla protein is a broad-spectrum beta-lactamase that greatly contributes to antibiotic resistance by hydrolyzing penicillins and cephalosporins (including third-generation drugs). Beta-lactamase CTX-M-1/Bla Protein, E.coli (His) is the recombinant E. coli-derived Beta-lactamase CTX-M-1/Bla protein, expressed by E. coli , with N-His labeled tag.
MetC protein is a multifunctional enzyme that catalyzes the cleavage of cystathionine to homocysteine, pyruvate, and ammonia, which is essential for methionine biosynthesis. It also acts as a cysteine desulfurase, converting cysteine into sulfide. MetC Protein, E.coli (His) is the recombinant E. coli-derived MetC protein, expressed by E. coli , with N-His labeled tag.
ACPS Protein, Streptococcus pyogenes serotype M28 (Sf9, His-Myc), a 4-phosphopantetheinyl transferase, activates two distinct acyl carrier proteins (ACPs) that are present in fatty acid synthase (FAS) systems FAS-I and FAS-II, the ACP-I domain and the mycobacterial ACP-II protein (ACPM), respectively.
Enolase 1/ENO1 Proteins, as a glycolytic enzyme, convert 2-phosphoglycerate to phosphoenolpyruvate and have diverse roles in cellular processes like growth control, hypoxia tolerance, and allergic responses. They also function in the fibrinolytic system and stimulate immunoglobulin production, showing their involvement in immune responses. Enolase 1/ENO1 Protein, Mouse (His) is the recombinant mouse-derived Enolase 1/ENO1 protein, expressed by E. coli , with N-10*His labeled tag.
Glucose-6-phosphate isomerase protein exists in the cytoplasm and has dual functions. It converts glucose-6-phosphate into fructose-6-phosphate, playing a vital role in glycolysis and gluconeogenesis. Glucose-6-phosphate isomerase Protein, Mouse (His-B2M) is the recombinant mouse-derived Glucose-6-phosphate isomerase protein, expressed by E. coli , with N-6*His, B2M labeled tag.
GUCY2C, a guanylyl cyclase, crucially catalyzes cGMP synthesis from GTP. As a receptor for E. coli heat-stable enterotoxin, GUCY2C significantly stimulates cGMP accumulation in mammalian cells, emphasizing its role in mediating responses to specific external stimuli and showcasing intricate regulatory mechanisms in cellular signaling. GUCY2C/Guanylyl cyclase C Protein, Canine (HEK293, His) is the recombinant canine-derived GUCY2C/Guanylyl cyclase C protein, expressed by HEK293 , with C-His labeled tag.
Coagulation factor XII (F12) is a serum glycoprotein that plays multiple roles in initiating blood coagulation, fibrinolysis, and the production of bradykinin and angiotensin. It is involved in these complex processes, including cleavage of prekallikrein to form kallikrein, which subsequently cleaves factor XII initially to α-factor XIIa and then, after trypsin cleavage, to β-factor XIIa. Coagulation Factor XII/F12 Protein, Pig (P. pastoris, His) is the recombinant pig-derived F12/Coagulation Factor XII, Pig, expressed by P. pastoris , with N-6*His labeled tag.
The MutT protein maintains the genome by hydrolyzing 8-oxo-deoxyguanosine triphosphate (8-oxo-dGTP) and 8-oxo-guanosine triphosphate (8-oxo-GTP) to their corresponding monophosphates. Integrity plays a key role. This prevents misincorporation of 8-oxoGua into DNA and RNA, ensuring the fidelity of the nucleotide library. MutT Protein, E.coli (His-SUMO) is the recombinant E. coli-derived MutT protein, expressed by E. coli , with N-His, N-SUMO labeled tag.
LOXL4 Protein potentially modulates collagenous extracellular matrix formation, suggesting a role in regulating assembly or stability of collagen fibers. Its involvement indicates a contribution to the structural integrity of tissues. The specific mechanisms and contexts of LOXL4 in collagen matrix modulation are areas of interest, emphasizing its potential significance in tissue development and maintenance. Lysyl oxidase homolog 4 Protein, Mouse (His) is the recombinant mouse-derived Lysyl oxidase homolog 4 protein, expressed by E. coli , with N-His labeled tag.
CFB is an important component of the alternative pathway of the complement system and is cleaved by factor D, producing two fragments: Ba and Bb. The Bb fragment is characterized as a serine protease and subsequently forms a complex with complement factor 3b, ultimately producing a C3 or C5 convertase. Complement Factor B/CFB Protein, Mouse (His) is the recombinant mouse-derived CFB protein, expressed by E. coli , with N-6*His labeled tag.
EGLP/GPX5 may constitute a protective system similar to glutathione peroxidase, protecting sperm membrane lipids from peroxidative damage. Despite the limited enzyme activity, the protective effect suggests an effect beyond enzyme function. EGLP/GPX5 Protein, Pig (His-Myc) is the recombinant pig-derived EGLP/GPX5 protein, expressed by E. coli , with N-10*His, C-Myc labeled tag.
Hadh; Hadhsc; Mschad; Schad; Hydroxyacyl-coenzyme A dehydrogenase; mitochondrial; HCDH; EC 1.1.1.35; Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase; Short-chain 3-hydroxyacyl-CoA dehydrogenase
HCDH Protein, pivotal in mitochondrial fatty acid beta-oxidation, manages the third step for medium and short-chain 3-hydroxy fatty acyl-CoAs (C4 to C10). Beyond lipid metabolism, HCDH regulates insulin secretion by inhibiting glutamate dehydrogenase 1 (GLUD1) activation, a key enzyme in amino acid-induced insulin secretion. HCDH emerges as a pivotal factor in regulating cellular processes related to energy metabolism and glucose homeostasis. HCDH Protein, Mouse (His-SUMO) is the recombinant mouse-derived HCDH protein, expressed by E. coli , with N-His, N-SUMO labeled tag.
The elastase IIIB/CELA3B protein exhibits remarkable efficiency as a protease, showing a clear preference for alanine specificity while exhibiting limited elastolytic activity. This unique zymogram makes this protein a promising candidate for precise substrate cleavage, especially when processing alanine-rich substrates. Elastase IIIB/CELA3B Protein, Mouse (Myc, His) is the recombinant mouse-derived Elastase IIIB/CELA3B protein, expressed by E. coli , with N-His, C-Myc labeled tag.
The HSPA5/GRP-78 protein is an endoplasmic reticulum chaperone involved in protein folding and quality control. It interacts with DNAJC10/ERdj5 to fold and degrade misfolded proteins. HSPA5/GRP-78 Protein, Mouse (P.pastoris, His) is the recombinant mouse-derived HSPA5/GRP-78 protein, expressed by P. pastoris , with N-6*His, N-His labeled tag.
GUCY2C, a guanylyl cyclase, crucially catalyzes cGMP synthesis from GTP.As a receptor for E.coli heat-stable enterotoxin, GUCY2C significantly stimulates cGMP accumulation in mammalian cells, emphasizing its role in mediating responses to specific external stimuli and showcasing intricate regulatory mechanisms in cellular signaling.GUCY2C/Guanylyl cyclase C Protein, Rat (HEK293, Myc, His) is the recombinant rat-derived GUCY2C/Guanylyl cyclase C protein, expressed by HEK293 , with N-His, C-Myc labeled tag.
The HSPA5/GRP-78 protein is an endoplasmic reticulum chaperone involved in protein folding and quality control. It interacts with DNAJC10/ERdj5 to fold and degrade misfolded proteins. HSPA5/GRP-78 Protein, Mouse (P.pastoris, His, solution) is the recombinant mouse-derived HSPA5/GRP-78 protein, expressed by P. pastoris , with N-His labeled tag.
Dxr/DXP Reductoisomerase is pivotal in isoprenoid biosynthesis, catalyzing the rearrangement and reduction of DXP to yield MEP. This step is critical in forming isoprenoid precursors, essential for cellular processes and metabolite synthesis. The enzyme's activity emphasizes its significance in regulating isoprenoid biosynthesis and cellular functions. Dxr/DXP reductoisomerase Protein, E.coli (Myc, His) is the recombinant E. coli-derived Dxr/DXP reductoisomerase protein, expressed by E. coli , with C-Myc, N-10*His labeled tag.
Glucose-6-phosphate isomerase protein is a key player in glycolysis, catalyzing the conversion of glucose-6-phosphate into fructose-6-phosphate in the cytoplasm. It carries out this reaction reversibly during gluconeogenesis. Glucose-6-phosphate isomerase Protein, Human (His) is the recombinant human-derived Glucose-6-phosphate isomerase protein, expressed by E. coli , with N-6*His labeled tag.
The ACAT1 protein is a key enzyme in mitochondrial beta-oxidation and plays a crucial role in breaking down fatty acids into acetyl-CoA. In the final step, ACAT1 catalyzes the thiolytic cleavage of 3-oxoacyl-CoA to generate acetyl-CoA and shortened fatty acyl-CoA. ACAT1 Protein Protein, Human (His) is the recombinant human-derived ACAT1 protein, expressed by E. coli , with N-His labeled tag.
The ACAT1 protein is a key enzyme in mitochondrial beta-oxidation and plays a crucial role in breaking down fatty acids into acetyl-CoA. In the final step, ACAT1 catalyzes the thiolytic cleavage of 3-oxoacyl-CoA to generate acetyl-CoA and shortened fatty acyl-CoA. ACAT1 Protein Protein, Human is the recombinant human-derived ACAT1, expressed by E. coli , with tag Free labeled tag.
The Matriptase/ST14 catalytic domain protein exhibits serine-type endopeptidase activity and is critical in processes as diverse as placental branching and neural tube closure. It is an extrinsic component of the plasma membrane and is expressed in structures such as the digestive system, early concepts, genitourinary system, pituitary gland, and sense organs. Matriptase/ST14 Catalytic Domain Protein, Mouse (His) is the recombinant mouse-derived Matriptase/ST14 Catalytic Domain protein, expressed by E. coli , with N-6*His labeled tag.
The Matriptase/ST14 catalytic domain protein originates from epithelial cells, forms a complex with HAI-1, and is activated by sphingosine-1-phosphate. It cleaves and activates hepatocyte growth factor/scatter factor and urokinase plasminogen activator, suggesting its role as an activator of other proteases and potential growth factors. Matriptase/ST14 Catalytic Domain Protein, Human (His) is the recombinant human-derived Matriptase/ST14 Catalytic Domain protein, expressed by E. coli , with N-6*His labeled tag.
LpxC protein serves as a key enzyme in lipid A biosynthesis by catalyzing the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine, marking a key and crucial step in this important pathway. Through this enzymatic process, LpxC promotes the conversion of its substrate into UDP-3-O-myristoylglucosamine and acetate, making a significant contribution to lipid A biosynthesis. LpxC Protein, E.coli (His) is the recombinant E. coli-derived LpxC protein, expressed by E. coli , with N-His labeled tag.
PLBD2 Protein, a putative phospholipase, interacts with insulin-like growth factor 2 receptor (IGF2R), suggesting involvement in growth and signaling pathways. Despite unknown details about its phospholipase activity, PLBD2's exploration may unveil insights into its role in cellular homeostasis and regulatory mechanisms. PLBD2 Protein, Mouse (His) is the recombinant mouse-derived PLBD2 protein, expressed by E. coli , with N-His labeled tag.
Acetyl-CoA synthetase 1/AceCS Protein, Mouse (His) is an enzyme that converts acetate to acetyl-CoA, which supplies acetyl-CoA for tumor cells by capturing acetate as a carbon source under stressed conditions.
PLA2G2D protein is a secreted calcium-dependent phospholipase A2 that targets extracellular lipids and has anti-inflammatory and immunosuppressive functions.It hydrolyzes the fatty acyl group at the sn-2 position, preferentially hydrolyzing phosphatidylethanolamine and phosphatidylglycerol.PLA2G2D Protein, Human (His-SUMO) is the recombinant human-derived PLA2G2D protein, expressed by E.coli , with N-His, N-SUMO labeled tag.
The azoreductase/NQO1 protein reduces quinones to hydroquinone using NADH or NADPH as an electron donor.Azoreductase/NQO1 Protein, Mouse (P.pastoris, His) is the recombinant mouse-derived Azoreductase/NQO1 protein, expressed by P.pastoris , with N-6*His labeled tag.
GUCY2C, a guanylyl cyclase, catalyzes cGMP synthesis from GTP and acts as a receptor for E. coli heat-stable enterotoxin, stimulating cGMP accumulation in expressing mammalian cells. Additionally, endogenous peptides guanylin and uroguanylin activate GUCY2C. This multifaceted role underscores intricate regulatory mechanisms in cellular signaling and GUCY2C's responsiveness to various stimuli, as confirmed by studies. GUCY2C/Guanylyl cyclase C Protein, Human (HEK293, Fc) is the recombinant human-derived GUCY2C/Guanylyl cyclase C protein, expressed by HEK293 , with C-hFc labeled tag.
GUCY2C, a guanylyl cyclase, catalyzes cGMP synthesis from GTP and acts as a receptor for E. coli heat-stable enterotoxin, stimulating cGMP accumulation in expressing mammalian cells. Additionally, endogenous peptides guanylin and uroguanylin activate GUCY2C. This multifaceted role underscores intricate regulatory mechanisms in cellular signaling and GUCY2C's responsiveness to various stimuli, as confirmed by studies. GUCY2C/Guanylyl cyclase C Protein, Human (HEK293, His-Avi) is the recombinant human-derived GUCY2C/Guanylyl cyclase C protein, expressed by HEK293 , with C-Avi, C-His labeled tag.
GUCY2C, a guanylyl cyclase, catalyzes cGMP synthesis from GTP and acts as a receptor for E. coli heat-stable enterotoxin, stimulating cGMP accumulation in expressing mammalian cells. Additionally, endogenous peptides guanylin and uroguanylin activate GUCY2C. This multifaceted role underscores intricate regulatory mechanisms in cellular signaling and GUCY2C's responsiveness to various stimuli, as confirmed by studies. GUCY2C/Guanylyl cyclase C Protein, Human (HEK293, N-His) is the recombinant human-derived GUCY2C/Guanylyl cyclase C protein, expressed by HEK293 , with N-10*His labeled tag.
GUCY2C, a vital guanylyl cyclase, catalyzes the synthesis of cyclic cGMP from GTP. GUCY2C/Guanylyl cyclase C Protein, Mouse (HEK293, His-Avi) is the recombinant mouse-derived GUCY2C/Guanylyl cyclase C protein, expressed by HEK293 , with C-Avi, C-His labeled tag.
GZMA/granzyme A is enriched in cytotoxic T cells and natural killer cells and can induce caspase-independent pyroptosis after delivery to target cells. With substrate specificity for lysine or arginine residues, GZMA cleaves APEX1 and the nucleosome assembly protein SET, thereby disrupting their activity. GZMA/Granzyme A Protein, Mouse (His) is the recombinant mouse-derived GZMA/Granzyme A protein, expressed by E. coli , with C-6*His labeled tag.
The PLBD2 protein is a putative phospholipase that may participate in cellular processes by interacting with IGF2R. Although the function and mechanism of the enzyme are unclear, its association with IGF2R suggests involvement in the insulin-like growth factor 2 receptor-related signaling pathway. PLBD2 Protein, Rat (His-SUMO) is the recombinant rat-derived PLBD2 protein, expressed by E. coli , with N-His, N-SUMO labeled tag.
RIPK3 Protein, participates in programmed necrosis (necroptosis) and apoptosis, contributing to diverse cellular processes. RIPK3 Protein, Mouse (P.pastoris, His) is the recombinant mouse-derived RIPK3 protein, expressed by P. pastoris , with N-6*His labeled tag.
CYP51 Proteinas is a sterol 14α-demethylase that acts with an unknown physiological substrate and accepts electrons from the iron-sulfur ferredoxin Fdx. In vitro, it catalyzes the C14-demethylation of lanosterol, 24,25-dihydrolanosterol, and obtanyol, showing stereoselectivity in producing 8,14-diene. CYP51 Protein, Mycobacterium tuberculosis (sf9, His) is the recombinant CYP51 protein, expressed by Sf9 insect cells , with N-10*His labeled tag.
CAPN1 protein, a calcium-regulated non-lysosomal thiol-protease, facilitates cytoskeletal remodeling and signal transduction. It selectively cleaves substrates involved in these processes, including CTBP1 at 'Asn-375', 'Gly-388', and 'His-410'. CAPN1 also activates caspase-7 (CASP7), highlighting its role in regulating cellular functions. CAPN1 Protein, Mouse (His) is the recombinant mouse-derived CAPN1 protein, expressed by E. coli , with N-6*His labeled tag.
ERG11 Proteinas is a sterol 14α-demethylase, a key enzyme in the ergosterol biosynthetic pathway, particularly in the late pathway that occurs in the endoplasmic reticulum membrane. ERG11 catalyzes the three-step removal of the 14α-methyl group from lanosterol, releasing it as a formate, resulting in the conversion of the sterol into a key intermediate in ergosterol biosynthesis. ERG11 Protein, Saccharomyces cerevisiae (GST) is the recombinant ERG11 protein, expressed by E. coli , with N-GST labeled tag.
GUCY2C, a guanylyl cyclase, catalyzes cGMP synthesis from GTP and acts as a receptor for E. coli heat-stable enterotoxin, stimulating cGMP accumulation in expressing mammalian cells. Additionally, endogenous peptides guanylin and uroguanylin activate GUCY2C. This multifaceted role underscores intricate regulatory mechanisms in cellular signaling and GUCY2C's responsiveness to various stimuli, as confirmed by studies. GUCY2C/Guanylyl cyclase C Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived GUCY2C/Guanylyl cyclase C protein, expressed by HEK293 , with C-Avi, C-His labeled tag.
GUCY2C, a vital guanylyl cyclase, catalyzes the synthesis of cyclic cGMP from GTP. GUCY2C/Guanylyl cyclase C Protein, Mouse (HEK293, N-His, C-Myc) is the recombinant mouse-derived GUCY2C/Guanylyl cyclase C protein, expressed by HEK293 , with C-Myc, N-10*His labeled tag.
GUCY2C, a vital guanylyl cyclase, catalyzes the synthesis of cyclic cGMP from GTP. GUCY2C/Guanylyl cyclase C Protein, Mouse (Biotinylated, HEK293, His-Avi) is the recombinant mouse-derived GUCY2C/Guanylyl cyclase C protein, expressed by HEK293 , with C-Avi, C-His labeled tag.
DCT (Dopachrome tautomerase) is pivotal in melanin biosynthesis, catalyzing the conversion of L-dopachrome to 5,6-dihydroxyindole-2-carboxylic acid (DHICA), a critical step in melanin synthesis. DCT's enzymatic activity is integral to the complex processes governing melanin production, emphasizing its role in skin pigmentation and the regulation of melanin-related functions. DCT Protein, Mouse (His-SUMO) is the recombinant mouse-derived DCT protein, expressed by E. coli , with N-10*His, N-SUMO labeled tag.
GZMA/granzyme A is enriched in cytotoxic T cells and natural killer cells and can induce caspase-independent pyroptosis after delivery to target cells. With substrate specificity for lysine or arginine residues, GZMA cleaves APEX1 and the nucleosome assembly protein SET, thereby disrupting their activity. GZMA/Granzyme A Protein, Mouse (His-B2M) is the recombinant mouse-derived GZMA/Granzyme A protein, expressed by E. coli , with N-6*His, N-B2M labeled tag.
DNase1L3 protein has DNA hydrolytic activity and can effectively cleave single-stranded and double-stranded DNA to generate 3'-OH terminal fragments. It cleaves chromatin into nucleosomal units and participates in internucleosomal DNA fragmentation during apoptosis and necrosis. DNase1L3 Protein, Mouse (His) is the recombinant mouse-derived DNase1L3 protein, expressed by E. coli , with C-6*His labeled tag.
RET protein is an important receptor tyrosine protein kinase that drives a variety of cellular processes such as proliferation, migration, and differentiation when bound to GDNF ligand. It coordinates organogenesis, shapes the enteric nervous system and promotes kidney development. RET Protein, Mouse (HEK293, His) is the recombinant mouse-derived RET protein, expressed by HEK293 , with C-6*His labeled tag and F174S mutation.
PHKG1 is the catalytic subunit of phosphorylase b kinase (PHK), which plays a key role in the neural and hormonal regulation of glycogenolysis (glycogen breakdown) by phosphorylating and activating glycogen phosphorylase. PHKG1 Protein, Human (Active, sf9, GST) is the recombinant human-derived PHKG1, expressed by Sf9 insect cells , with GST labeled tag. ,
The EphA3 protein is a receptor tyrosine kinase that promiscuously binds to membrane-bound ephrin ligands to initiate bidirectional signaling. Activation of EphA3 is known to preferentially bind to EFNA5 and regulates cell-cell adhesion, cytoskeletal organization, and migration. EphA3 Protein, Human (HEK293, His) is the recombinant human-derived EphA3 protein, expressed by HEK293 , with C-6*His labeled tag.
CBS, a hydro-lyase, initiates the transsulfuration pathway by catalyzing the beta-replacement reaction, converting L-serine to L-cystathionine using L-homocysteine. This process eliminates L-methionine and the potentially harmful metabolite L-homocysteine. CBS, beyond its catabolic role, contributes to hydrogen sulfide production, serving as a gasotransmitter with signaling and cytoprotective effects, particularly on neurons. CBS Protein, Human (His) is the recombinant human-derived CBS protein, expressed by E. coli , with N-6*His labeled tag.
The ENPP-2 protein catalyzes the hydrolysis of lysophospholipids (especially lysophosphatidylcholine) to produce the signaling molecule lysophosphatidic acid (LPA). It also acts on sphingosine phosphocholine to produce sphingosine 1-phosphate, which affects cell movement. ENPP-2 Protein, Human (HEK293, His) is the recombinant human-derived ENPP-2 protein, expressed by HEK293 , with C-6*His labeled tag.
TRIM21 is an E3 ubiquitin protein ligase that forms complexes with E2 enzymes including UBE2D1 and UBE2E2.It cooperates with UBE2D2 to ubiquitinate USP4, IKBKB and itself, and binds to SCF E3 ligase to mediate ubiquitination of CDKN1B.TRIM21 Protein, Mouse (His-SUMO) is the recombinant mouse-derived TRIM21 protein, expressed by E.coli , with N-His, N-SUMO labeled tag.
The UBE2R1/CDC34 protein is an important ubiquitin-proteasome system component that functions as an E2 ubiquitin-conjugating enzyme, capable of proficiently accepting ubiquitin from the E1 complex and catalyzing its covalent attachment to a variety of protein substrates. . In vitro, UBE2R1 efficiently mediates “Lys-48”-linked polyubiquitination. UBE2R1/CDC34 Protein, Human (Sf9, His, Strep) is the recombinant human-derived UBE2R1/CDC34 protein, expressed by Sf9 insect cells , with N-Strep, N-His labeled tag.
The PKLR protein is a pyruvate kinase that plays a critical role in glycolysis, converting phosphoenolpyruvate to pyruvate and producing ATP.As a key enzyme, PKLR mediates the final steps of glycolysis, contributing to energy production.PKLR Protein, Rat (P.pastoris, His) is the recombinant rat-derived PKLR protein, expressed by P.pastoris , with N-6*His labeled tag.
The AKT2 protein is a serine/threonine protein kinase in the AKT family that is critical for metabolism, proliferation, survival, growth, and angiogenesis. It phosphorylates more than 100 substrates, coordinates insulin-induced SLC2A4/GLUT4 translocation, affects glucose uptake, and controls glycogen storage. AKT2 Protein, Human (Active, sf9, GST) is the recombinant human-derived AKT2, expressed by Sf9 insect cells , with GST labeled tag.
CSNK1E protein is a casein kinase that preferentially phosphorylates acidic proteins such as casein. CSNK1E Protein, Human (His) is the recombinant human-derived CSNK1E protein, expressed by E. coli , with N-6*His labeled tag.
The UbcH5b/UBE2D2 protein is an important cellular mediator that accepts ubiquitin from the E1 complex and catalyzes multifunctional “Lys-48”-linked polyubiquitination on target proteins. In addition to its catalytic role, it also concentrates and selectively degrades short-lived proteins and contributes to E6/E6-AP-induced ubiquitination of p53/TP53. UbcH5b/UBE2D2 Protein, Human is the recombinant human-derived UbcH5b/UBE2D2 protein, expressed by E. coli , with tag free.
The AKT3 protein, like AKT1 and AKT2, is an important member of the AKT kinase family and plays a central role in a variety of cellular processes, including metabolism, proliferation, survival, growth, and angiogenesis. AKT3 has more than 100 reported targets and coordinates complex signaling pathways that control glucose uptake, regulate glycogen storage, and influence neurogenesis. AKT3 Protein, Human (Active, sf9, GST) is the recombinant human-derived AKT3, expressed by Sf9 insect cells , with GST labeled tag.
CDC42BPB protein is a key serine/threonine protein kinase downstream of CDC42 that controls cytoskeletal dynamics and cell migration. CDC42BPB phosphorylates PPP1R12C and MYL9/MLC2, regulates actin reorganization and shapes cell dynamics. MRCKβ Protein, Human (sf9, GST) is the recombinant human-derived MRCKβ, expressed by Sf9 insect cells , with GST labeled tag. ,
VEGFR-2 protein is a tyrosine protein kinase receptor for VEGFA, VEGFC and VEGFD and is critical in angiogenesis, blood vessel development and embryonic hematopoiesis. It promotes endothelial cell function and actin cytoskeletal reorganization. VEGFR-2 Protein, Human (1355a.a, sf9, GST) is the recombinant human-derived VEGFR-2, expressed by Sf9 insect cells , with GST labeled tag. ,
DCT Protein is essential in melanin biosynthesis, catalyzing the conversion of L-dopachrome to 5,6-dihydroxyindole-2-carboxylic acid (DHICA), a pivotal step in melanin synthesis. DCT Protein, Human (His-SUMO) is the recombinant human-derived DCT protein, expressed by E. coli , with N-SUMO, N-10*His labeled tag.
The P4HB protein is a multifunctional entity that catalyzes disulfide bonding processes at the cell surface and within cells. As a reductase, it modifies outer surface proteins and participates in the formation of disulfide bonds in nascent proteins. P4HB Protein, Human (His) is the recombinant human-derived P4HB protein, expressed by E. coli , with N-6*His labeled tag.
The MKK6 protein is a dual-specificity kinase involved in the MAP kinase pathway. MAP2K6 Protein, Human (Sf9, His) is the recombinant human-derived MAP2K6 protein, expressed by Sf9 insect cells , with N-6*His labeled tag.
PAK3 is a serine/threonine kinase that plays a key role in multiple signaling pathways, affecting cytoskeletal dynamics, cell migration, and cell cycle. Its involvement in dendritic spine morphogenesis and synapse formation emphasizes its importance in neuronal processes. PAK3 Protein, Human (sf9) is the recombinant human-derived PAK3, expressed by Sf9 insect cells , with tag Free labeled tag. ,
a disintegrin and metalloprotease domain 10; a disintegrin and metalloproteinase domain 10; AD10; ADAM 10; ADAM metallopeptidase domain 10; ADAM10; CD156c antigen; CD156c; CDw156; disintegrin and metalloproteinase domain-containing protein 10; EC 3.4.24; HsT18717; kuz; Kuzbanian protein homolog; Kuzbanian; MADM; MADMEC 3.4.24.81; Mammalian disintegrin-metalloprotease
The ADAM10 protein cleaves TNF-α precursor, releasing a soluble form, and mediates the proteolytic release of JAM3 and various cell surface proteins. ADAM10 Protein, Human (HEK293, His) is the recombinant human-derived ADAM10 protein, expressed by HEK293 , with C-10*His labeled tag.
The PNPLA2 protein catalyzes the hydrolysis of triglycerides, preferably long-chain fatty acid esters, in lipid droplets. PNPLA2 Protein, Human (His-SUMO) is the recombinant human-derived PNPLA2 protein, expressed by E. coli , with N-SUMO, N-6*His labeled tag.
RAF1 is a kinase that links Ras GTPases to the MAPK/ERK cascade, influencing cell fate decisions. Activated RAF1 initiates the MAPK cascade and phosphorylates MEK1/2 and ERK1/2. RAF1 Protein, Human (Y340D,Y341D, sf9, His, GST) is the recombinant human-derived RAF1, expressed by Sf9 insect cells , with His, GST labeled tag. ,
CDK19 plays a key role in cellular homeostasis and developmental programming. CDK19 can interact with p53 to inhibit p53-mediated transcription of p21, and regulates the proliferation of hematopoietic stem cells and acute myeloid leukemia cells. Besides, CDK19 is the paralog of CDK8. CDK8 and CDK19 can cooperate with each other in stimulating NFκB-induced transcription and Dengue virus replication. CDK19-CCNC-MED12 Protein, Human (sf9, GST, Flag, His) is the recombinant human-derived CDK19-CCNC-MED12, expressed by Sf9 insect cells , with N-6*His, N-GST, N-Flag labeled tag. ,
The DDX39B protein intricately coordinates nuclear mRNA export and is specifically associated with spliced mRNA as a key component of the TREX complex. This coupling of mRNA transcription, processing, and export involves rounds of ATP-dependent hydrolysis, recruiting components such as ALYREF/THOC and CHTOP. DDX39B Protein, Human (GST) is the recombinant human-derived DDX39B protein, expressed by E. coli , with N-GST labeled tag.
ST3GAL3 protein plays a central role in cellular processes by catalyzing the formation of NeuAc-alpha-2,3-Gal-beta-1,4-GlcNAc-, NeuAc-alpha-2,3-Gal-beta-1,3-GlcNAc- and NeuAc-α-2,3-Gal-beta-1,3-GalNAc- sequences are present in the terminal carbohydrate groups of glycoproteins and glycolipids. ST3GAL3 Protein, Human (His-SUMO) is the recombinant human-derived ST3GAL3 protein, expressed by E. coli , with N-His, N-SUMO labeled tag.
NOS3; Nitric oxide synthase; endothelial; Constitutive NOS; cNOS; EC-NOS; Endothelial NOS; eNOS; NOS type III; NOSIII
WB, IHC-F, IHC-P, ICC/IF, ELISA
Human, Mouse, Rat
eNOS Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 133 kDa, targeting to eNOS. It can be used for WB,IHC-F,IHC-P,ICC/IF,ELISA assays with tag free, in the background of Human, Mouse, Rat.
MPO Antibody is an unconjugated, approximately 84 kDa, rabbit-derived, anti-MPO polyclonal antibody. MPO Antibody can be used for: ELISA, IHC-P, IHC-F, ICC, IF expriments in human, mouse, and predicted: rat, dog, horse, rabbit, guinea pig background without labeling.
Thymidine Kinase Antibody (YA2195) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2195), targeting Thymidine Kinase, with a predicted molecular weight of 25 kDa (observed band size: 25 kDa). Thymidine Kinase Antibody (YA2195) can be used for WB, IP experiment in human background.
MPO Antibody is an unconjugated, approximately 84 kDa, mouse-derived, anti-MPO monoclonal antibody. MPO Antibody can be used for: WB, IHC-P, IF-Cell, IF-Tissue expriments in human, mouse, rat background without labeling.
MPO Antibody is an unconjugated, approximately 84 kDa, mouse-derived, anti-MPO monoclonal antibody. MPO Antibody can be used for: WB, IHC-P, FC, IF-Cell, IF-Tissue expriments in human, mouse, rat background without labeling.
HSD3B1 Antibody is an unconjugated, approximately 42 kDa, rabbit-derived, anti-HSD3B1 monoclonal antibody. HSD3B1 Antibody can be used for: WB,ICC/IF expriments in human background without labeling.
Glutathione Peroxidase 4 Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 22 kDa, targeting to Glutathione Peroxidase 4. It can be used for WB,IHC-F,IHC-P,ICC/IF assays with tag free, in the background of Human, Mouse, Rat.
PCPTP1 Antibody (YA1549) is a non-conjugated IgG antibody, targeting PCPTP1, with a predicted molecular weight of 74 kDa (observed band size: 74 kDa). PCPTP1 Antibody (YA1549) can be used for WB experiment in rat background.
Superoxide Dismutase 3 Antibody (YA2420) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2420), targeting Superoxide Dismutase 3, with a predicted molecular weight of 26 kDa (observed band size: 26 kDa). Superoxide Dismutase 3 Antibody (YA2420) can be used for WB, IHC-P experiment in human background.
Cdk7 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 39 kDa, targeting to Cdk7. It can be used for WB assays with tag free, in the background of Human.
HDAC4 Antibody (YA741) is a non-conjugated and Mouse origined monoclonal antibody about 119 kDa, targeting to HDAC4 (4A3). It can be used for WB,IP assays with tag free, in the background of Human, Mouse, Rat, Monkey.
Choline O acetyltransferase; Choline O acetyltransferase; Acetyl CoA choline O acetyltransferase; Acetyl CoA:choline O acetyltransferase; ChAT; CHOACTase; Choline acetylase; choline acetyltransferase; CMS1A; CMS1A2; EC 2.3.1.6; OTTHUMP00000019583; OTTHUMP00000019584; CLAT_HUMAN.
WB, IHC-P, ICC/IF, IP, FC
Human, Mouse, Rat
ChAT Antibody is an unconjugated, approximately 82 kDa, rabbit-derived, anti-ChAT monoclonal antibody. ChAT Antibody can be used for: WB,IHC-P,ICC/IF,FC,IPexpriments in human, mouse, rat background without labeling.
Adhesion related kinase; AI323647; Ark; Axl; AXL oncogene; AXL rECeptor tyrosine kinase; AXL transforming gene; AXL transforming sequence/gene; EC 2.7.10.1; JTK11; Oncogene AXL; Tyro7; Tyrosine protein kinase rECeptor UFO; Tyrosine-protein kinase rECeptor UFO; UFO; UFO_HUMAN.
WB, ELISA, IHC-P, IHC-F, ICC/IF
Human, Mouse
AXL Antibody is an unconjugated, approximately 95 kDa, rabbit-derived, anti-AXL polyclonal antibody. AXL Antibody can be used for: WB, ELISA, IHC-P, IHC-F, IF expriments in human, mouse, and predicted: rat, dog, horse, rabbit background without labeling.
UCHL1 / PGP9.5; UCHL1; B220; CD 45; CD45; cd45 antigen; EC3.1.3.48; GP 180; GP180; Human homolog of severe combined immunodeficiency due to PTPRC deficiency; L CA; L-CA; lca; Leukocyte common antigen; LY 5; LY5; Protein tyrosine phosphatase rECeptor type
WB, IHC-P, IHC-F, ICC/IF, IP
Human, Mouse, Rat
PGP9.5 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 25 kDa, targeting to PGP9.5. It can be used for WB,IHC-F,IHC-P,ICC/IF,IP assays with tag free, in the background of Human, Mouse, Rat.
Phosphatidylinositol 3-kinase catalytic subunit type 3 (EC:2.7.1.137); PI3-kinase type 3; PI3K type 3; PtdIns-3-kinase type 3; Phosphatidylinositol 3-kinase p100 subunit; Phosphoinositide-3-kinase class 3; hVps34; VPS34 antibodyPIK3C3;
WB, IHC-P
Human, Mouse, Rat
PIK3C3 Antibody (YA2789) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2789), targeting PIK3C3, with a predicted molecular weight of 102 kDa (observed band size: 102 kDa). PIK3C3 Antibody (YA2789) can be used for WB, IHC-P experiment in human, mouse, rat background.
Advanced glycosylation end product spECific rECeptor; Advanced glycosylation end product-spECific rECeptor; AGER; EC 2.7.11.22; LE 9211 A antigen; LE-9211-A antigen; MGC22357; MOK; RAGE 1; RAGE1; MOK protein kinase; RECeptor for advanced glycation endproducts; Renal tumor antigen 1; Renal tumor antigen; Renal cell carcinoma antigen (MOK protein kinase); Renal tumor antigen 1; RAGE_HUMAN.
WB, IHC-P, FC
Human, Mouse, Rat,
RAGE Antibody is an unconjugated, approximately 42 kDa, rabbit-derived, anti-RAGE polyclonal antibody. RAGE Antibody can be used for: WB, ELISA, IHC-P, IHC-F, Flow-Cyt, IF expriments in human, mouse, rat, background without labeling.
Phospho-PERK (Thr980) Antibody is an unconjugated, approximately 119 kDa, rabbit-derived, anti-PERK (Thr980) polyclonal antibody. Phospho-PERK (Thr980) Antibody can be used for: WB, ELISA, IHC-P, IHC-F, Flow-Cyt, IF expriments in human, mouse, rat, and predicted: dog, pig, cow, rabbit background without labeling.
Advanced glycosylation end product spECific rECeptor; Advanced glycosylation end product-spECific rECeptor; AGER; EC 2.7.11.22; LE 9211 A antigen; LE-9211-A antigen; MGC22357; MOK; RAGE 1; RAGE1; MOK protein kinase; RECeptor for advanced glycation endproducts; Renal tumor antigen 1; Renal tumor antigen; Renal cell carcinoma antigen (MOK protein kinase); Renal tumor antigen 1; RAGE_HUMAN.
WB, IHC-P, ICC/IF
Human, Mouse, Rat
RAGE Antibody is an unconjugated, approximately 42 kDa, rabbit-derived, anti-RAGE monoclonal antibody. RAGE Antibody can be used for: WB, IHC-P, IF-Tissue, mIHC expriments in human, mouse, rat, background without labeling.
DGAT1 Antibody is a rabbit-derived non-conjugated IgG antibody, targeting DGAT1, with a predicted molecular weight of 55 kDa (observed band size: 55 kDa). DGAT1 Antibody can be used for WB,IHC-P,IP experiments in human backgrounds.
ACE2 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 92 kDa, targeting to ACE2. It can be used for WB,ICC,IHC-P,IP assays with tag free, in the background of Human, Mouse, Hamster.
Phospho-eNOS (Ser1177) Antibody is an unconjugated, approximately 133 kDa, rabbit-derived, anti-eNOS (Ser1177) polyclonal antibody. Phospho-eNOS (Ser1177) Antibody can be used for: WB, ELISA, IHC-P, IHC-F, Flow-Cyt, IF expriments in human, mouse, and predicted: rat, dog, pig, cow, rabbit, sheep, guinea pig background without labeling.
FBP1 Antibody (YA1264) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1264), targeting FBP1. FBP1 Antibody (YA1264) can be used for WB, IF-Cell, IHC-P experiment in human,mouse,rat background.
CASP4 Antibody is a non-conjugated IgG antibody, targeting CASP4, with a predicted molecular weight of 43 kDa. CASP4 Antibody can be used for WB, ELISA experiment in human and rat background.
PSMB5/MB1 Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 26 kDa, targeting to PSMB5/MB1. It can be used for WB, IHC-P, IF-Cell, FC assays with tag free, in the background of Human,Mouse, Rat.
JNK Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 48 kDa, targeting to JNK. It can be used for WB,IP assays with tag free, in the background of Human, Mouse, Rat, Hamster.
JNK1 (1A4) Antibody is a non-conjugated and Mouse origined monoclonal antibody about 48 kDa, targeting to JNK1 (1A4). It can be used for WB,ICC/IF assays with tag free, in the background of Human, Mouse, Rat.
Alpha CaMKII; Calcium calmodulin dependent protein kinase II; Calcium/calmodulin dependent protein kinase II alpha B subunit; Calcium/calmodulin dependent protein kinase type II alpha chain; Calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha; Calcium/calmodulin-dependent protein kinase II alpha; Calcium/calmodulin-dependent protein kinase II-alpha; Calcium/calmodulin-dependent protein kinase type II subunit alpha; Calcium/calmodulin-dependent protein kinase type IIA; CaM kinase II alpha chain; CaM kinase II alpha subunit; CaM kinase II subunit alpha; CaMK II alpha subunit; CaMK-II subunit alpha; Camk2a; CAMKA; CaMKII; CaMKIINalpha; EC2.7.11.17; KCC2A_HUMAN; KIAA0968; MGC123320; MGC139375; MGC155201; mKIAA0968; PK2CDD; PKCCD; R74975; zgc:112538; zgc:123320;
WB, IP, FC, IHC-P
Human, Mouse, Rat
CaMKII alpha Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 54 kDa, targeting to CaMKII alpha. It can be used for WB,IP,FC,IHC-P assays with tag free, in the background of Human, Mouse, Rat.
Phospho-JNK1 (Thr183/Tyr185) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 48 kDa, targeting to Phospho-JNK1 (Thr183/Tyr185). It can be used for WB,IP assays with tag free, in the background of Human, Rat.
SRD5A2 Antibody is an unconjugated, approximately 28 kDa, rabbit-derived, anti-SRD5A2 monoclonal antibody. SRD5A2 Antibody can be used for: WB, IP expriments in human, rat background without labeling.
EC330 is a leukemia inhibitory factor (LIF) inhibitor. EC330 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
EC359 is a potent, selective, high affinity and orally active leukemia inhibitory factor receptor (LIFR) inhibitor with a Kd of 10.2 nM, which directly interacts with LIFR to effectively block LIF/LIFR interactions . EC359 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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