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  3. Enzymes & Regulators
  4. Lyases (EC 4)
  5. GUCY2C/Guanylyl cyclase C Protein, Mouse (CHO, His)

GUCY2C/Guanylyl cyclase C Protein, Mouse (CHO, His)

Cat. No.: HY-P704653
Handling Instructions Technical Support

GUCY2C, a vital guanylyl cyclase, catalyzes the synthesis of cyclic cGMP from GTP. GUCY2C/Guanylyl cyclase C Protein, Mouse (CHO, His) is the recombinant mouse-derived GUCY2C/Guanylyl cyclase C protein, expressed by CHO, with C-His labeled tag.

For research use only. We do not sell to patients.

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Description

GUCY2C, a vital guanylyl cyclase, catalyzes the synthesis of cyclic cGMP from GTP. GUCY2C/Guanylyl cyclase C Protein, Mouse (CHO, His) is the recombinant mouse-derived GUCY2C/Guanylyl cyclase C protein, expressed by CHO, with C-His labeled tag.
Background

GUCY2C, a guanylyl cyclase, plays a crucial role in catalyzing the synthesis of cyclic (cGMP) from GTP.
Species

Mouse
Source

CHO
Tag

C-His
Accession

Q3UWA6-1 (V20-M433)
Gene ID

14917
Molecular Construction
N-term
GUCY2C (V20-M433)
Accession # Q3UWA6-1
His
C-term
Synonyms
Guanylyl cyclase C; GC-C; STAR; GUCY2C; GUC2C; STA receptor; DIAR6; EC 4.6.1; GCC; GUC2CEC 4.6.1.2; MUCIL
Predicted Molecular Mass
49.0 kDa.
Molecular Weight

Approximately 80-100 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
Glycosylation
Yes
Purity

Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

GUCY2C/Guanylyl cyclase C Protein, Mouse (CHO, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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