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  5. MPO Antibody (YA3466)

MPO Antibody is an unconjugated, approximately 84 kDa, mouse-derived, anti-MPO monoclonal antibody. MPO Antibody can be used for: WB, IHC-P, FC, IF-Cell, IF-Tissue expriments in human, mouse, rat background without labeling.

For research use only. We do not sell to patients.

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Top Publications Citing Use of Products

【WB: Western Blot; IHC-P: Immunohistochemistry-Paraffin; IHC-F: Immunohistochemistry-Frozen; ICC/IF: Immunocytochemistry/Immunofluorescence; IF-Tissue: Immunofluorescence-Tissue; mIHC: Multiplex Immunohistochemical; IP: Immunoprecipitation; ChIP: Chromatin Immunoprecipitation; FC: Flow Cytometry; ELISA: Enzyme Linked Immunosorbent Assay】

  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

MPO Antibody is an unconjugated, approximately 84 kDa, mouse-derived, anti-MPO monoclonal antibody. MPO Antibody can be used for: WB, IHC-P, FC, IF-Cell, IF-Tissue expriments in human, mouse, rat background without labeling.
Background

MPO is part of the host defense system of polymorphonuclear leukocytes, responsible for microbicidal activity against a wide range of organisms. In stimulated PMNs, MPO catalyzes the production of hypohalous acids (primarily hypochlorous acid under physiological conditions) and other toxic intermediates, greatly enhancing PMN microbicidal activity. Additionally, MPO mediates the proteolytic cleavage of alpha-1-microglobulin to form t-alpha-1-microglobulin, which potently inhibits oxidation of low-density lipoprotein particles and limits vascular damage.
Gene ID
SwissProt ID
Synonyms
Myeloperoxidase; MPO; 89 kDa myeloperoxidase; 84 kDa yeloperoxidase; Myeloperoxidase heavy chain; EC 1.11.1.7; PERM_HUMAN.
Molecular Weight

Predicted band size: 84 kDa; Observed band size: 84/55/37 kDa
Purity

affinity purified
Subcellular Location

Lysosome.
Conjugation

Non-conjugated
Modification

Unmodified
RRID
Product Categories

Primary Antibody; Mouse Monoclonal Antibody
Clonality

Monoclonal
Host

Mouse
Reactivity

Human, Mouse, Rat
Dilution Ratio

WB: 1:2,000-1:5,000;IHC-P: 1:5,000-1:10,000;FC: 1:50-1:100;IF-Cell: 1:100;IF-Tissue: 1:1,000-1:2,000
Application

WB, IHC-P, ICC/IF, FC
Positive Control

HL-60 cell lysates, human colon tissue, human colon cancer tissue, human tonsil tissue, mouse colon tissue, rat colon tissue, HL-60.
Appearance

Liquid
Formulation

Supplied in 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Isotype

IgG1
Immunogen

Recombinant protein within human Myeloperoxidase aa 550-745.
Database

Entrez Gene: 4353 Human ; 17523 Mouse ; 303413 Rat

SwissProt: P05164 Human ; P11247 Mouse ;

OMIM: 254600 Human

Documentation
SDS (251 KB)

COA (206 KB)

User Guide for Antibodies (1077 KB)

MPO Antibody (YA3466) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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MPO Antibody (YA3466)
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HY-P83736
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